Class / Patent application number | Description | Number of patent applications / Date published |
514377000 | Nitrogen bonded directly to ring carbon of the oxazole ring | 8 |
20090209602 | CHEMICAL COMPOUNDS - Compounds of formula (I), or salts thereof, which inhibit acetyl CoA(acetyl coenzyme A):diacylglycerol acyltransferase (DGAT1) activity are provided, | 08-20-2009 |
20090275627 | ALPHA2B AND ALPHA2C AGONISTS - Described herein are compounds that can be useful as bioactive agents. More specifically, the compounds described herein can be useful as both α | 11-05-2009 |
20100010060 | Isoindolin-1-One-, Isoindolin-3-One- and Isoindolin-1,3-Dione-Derivatives and Use Thereof - The invention relates to novel isoindolin-1-one, isoindolin-3-one and isoindoline-1,3-dione derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of thromboembolic disorders. | 01-14-2010 |
20100280085 | CHEMICAL COMPOUNDS - The use of a compound of formula (I) wherein X is (i), (ii) or (iii), where the substituents have the meanings assigned to them in claim | 11-04-2010 |
20110015241 | SUBSTITUTED HETEROCYCLES AND USE THEREOF - The invention relates to substituted heterocycles, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of thromboembolic disorders. | 01-20-2011 |
20140329871 | SMALL MOLECULE ANTI-FIBROTIC COMPOUNDS AND USES THEREOF - The present invention provides compounds having the general structural Formula (I): | 11-06-2014 |
20160158204 | PHARMACOLOGICAL STIMULATION TO FACILITATE AND RESTORE STANDING AND WALKING FUNCTIONS IN SPINAL CORD MOTOR DISORDERS - The invention relates to the selective targeting of specific α2 adrenergic receptor subtypes for facilitating and also restoring standing and walking in a subject affected by spinal cord disorders, in particular spinal cord injury. In particular, the improvement of locomotion by targeting specific receptor subtypes can be achieved by stimulation of the α2c receptor subtype using an α2c specific agonist or by blocking the α2a receptor subtype using α2a antagonists. A combination of an α2c agonist and an α2a antagonist is also provided for a synergistic effect. Alternatively, a large α2 agonist can be used in combination with an α2a antagonist to achieve specific stimulation of the α2c receptor. Pharmaceutical compositions, kit-of-parts and therapeutic systems comprising said agonists/antagonists as active agents are objects of the present invention. A robotic interface and epidural electric stimulation can also be used in combination with the compositions of the invention for restoring voluntary control of locomotion. | 06-09-2016 |
20190144400 | OXAZOLINE PSEUDODIMERS, PHARMACEUTICAL COMPOSITIONS AND THE USE THEREOF | 05-16-2019 |