| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 514368000 | Ring nitrogen is shared by the cyclos of the bicyclo ring system (e.g., tetramisole, etc.) | 12 |
| 20080249146 | Imidazole and Thioazole Derivatives as Antiviral Agents - The present invention relates to compounds of the formula (I), wherein R | 10-09-2008 |
| 20080287511 | Anthelmintic Imidazol-Thiazole Derivates - The present invention relates to the novel anthelmintic compound tetrahydro-furan-2-carboxylic acid-[3-(2,3,5,6-tetrahydro-imidazo[2,1-b]thiazol-6-yl)-phenyl]-amide and the pharmaceutically acceptable acid addition salts and the stereochemically isomeric forms thereof, as well as pharmaceutical compositions comprising said novel compound, processes for preparing said compound and compositions, and the use thereof as a medicine, in particular in treatment, control and prevention of endo- and ectoparasite infections in warm-blooded animals. | 11-20-2008 |
| 20100004299 | Imidazo[2,1-b]thiazoles and their use as pharmaceuticals - The present invention relates to derivatives of imidazo[2,1-b]thiazoles of formula I, | 01-07-2010 |
| 20100076036 | HETEROCYCLYL-SUBSTITUTED SULFONAMIDES FOR THE TREATMENT OF COGNITIVE OR FOOD INGESTION RELATED DISORDERS - The present invention relates to heterocyclyl-substituted sulfonamides with 5-HT | 03-25-2010 |
| 20100137384 | Anthelmintic Composition - The invention relates to a novel formulation having the advantage of including triclabendazole in solution. In addition a further anthelmintic may be included. The formulation is made by mixing the abamectin and benzyl alcohol and mixing this with triclabendazole and butyl dioxitol. The mix is then heated to dissolve the active, and allowed to cool at which stage the solution is diluted to volume with PEG 4000. The present invention overcomes the solubility difficulties of triclabendazole and presents the triclabendazole in a solution. | 06-03-2010 |
| 20110009461 | 2-AZA-BICYCLO[3.3.0]OCTANE DERIVATIVES - The invention relates to 2-aza-bicyclo[3.3.0]octane derivatives of Formula (I) wherein A, B, and R | 01-13-2011 |
| 20110053994 | POTENT IMMUNOSUPPRESSIVE AGENTS, DERIVATIVES AND USES - Provided herein include compositions, all related stereoisomers as well as pharmaceutically acceptable salts provided as simplified analogs of pateamine A, in which the analogs generally are devoid of the C3-amino and C5-methyl groups, also referred to as desmethyl, desamino-pateamine A. Suitable analogs provide anticancer and antiproliferative effects in vivo and in vitro by a novel drugs mechanism of action described herein for pateamine A, including inhibition of eIF4A-dependent translation initiation. As with pateamine A, as described herein, suitable analogs cause cell cycle arrest or induce apoptosis in transformed cells. However, toxicity of such compounds to slow growing normal cells is low. In addition, such analogs, like pateamine A, target translation initiation factors and are useful as anticancer and antiproliferative agents in subjects in need thereof. Moreover, the analogs, like pateamine A, are valuable molecular probes for evalutaion of eukaryotic translation initiation and as lead compounds for development of improved anticancer agents. | 03-03-2011 |
| 20110281920 | INJECTABLE PARASITICIDAL FORMULATIONS OF LEVAMISOLE AND MACROCYCLIC LACTONES - The present invention provides levamisole/macrocyclic lactone-containing injectable formulations that are effective against animal pests, including endoparasites. The formulations may be used for combating parasites in or on birds and mammals. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation of birds and mammals. | 11-17-2011 |
| 20120295941 | Method For Producing Intermediates For The Production Of Macrocycles That Are Inhibitors Of The Proteasomic Degradation of P27, Such As Argyrin And Derivatives Thereof - The present invention relates to an improved method for the synthesis of particular macrocycles that are inhibitors of the proteasomic degradation of p27, in particular argyrin and derivatives thereof. | 11-22-2012 |
| 20150313233 | ANTIMICROBIAL COMPOUNDS - The present invention relates to certain tetramic acid derivatives and, in particular, bicyclic tetramic acid derivatives that are suitable for use in the preparation and development of antimicrobial (e.g. antibacterial or antifungal) compositions. The present invention also relates to the use of such compounds as antimicrobial (e.g. antibacterial or antifungal agents) and, in particular, as topical antibacterial or antifungal agents. | 11-05-2015 |
| 20160113909 | METHODS AND COMPOSITIONS TO TREAT CANCER - Embodiments provided herein relate to methods and compositions for treating cancer. Some embodiments include treating lung cancers and renal cancers. | 04-28-2016 |
| 20160376290 | Imidazothiazole Derivatives as Modulators of TNF Activity - A series of substituted imidazo[2,1-b]thiazole derivatives, and analogues thereof, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders. | 12-29-2016 |
