Entries |
Document | Title | Date |
20080207702 | Use of Quaternary Pyridinium Salts as Vasoprotective Agents - The invention relates to the use of quaternary pyridium salts of formula (1) wherein R is NH | 08-28-2008 |
20080227831 | FOOD EXTRACTS FOR TREATMENT OF LIPOPROTEIN ABNORMALITIES AND SKIN DISEASES AND SKIN DISORDERS - The present invention is directed to N-methylnicotinamide containing food extracts, and their use in treating lipoprotein abnormalities and skin diseases and disorders. | 09-18-2008 |
20080234336 | Synergistic Imazalil Combinations - The present invention relates to synergistic combinations of the antifungal agent imazalil and another antifungal agent selected from the group consisting of boscalid, cyproconazole, pyraclostrobin, triflumizole, acibenzolar-S-methyl, carpropamid, fosetyl-Al, spiroxamine, tetraconazole and zoxamide for protecting plants, fruit or seeds against phytopathogenic fungi. | 09-25-2008 |
20080249140 | Quaternary 3 -Amido, N-Methylpyridinium Salts as Anti-Inflammatory Agents - A novel group of anti-inflammatory compounds are salts composed of the anion of a nonsteroidal anti-inflammatory acid drug (NSAID) and the cation N(1)-methylnicotinamide, which both anion and cation moieties alone exhibit anti-inflammatory activity, and which in this combination have advantages over the individual compounds and in comparison to commercial anti-inflammatory products. The compounds are produced in analogy to processes known in the art. They are used for the preparation of new pharmaceutical formulations with anti-inflammatory and analgesic activity. The new pharmaceutical formulations exhibit several advantageous properties over preparations of prior art. | 10-09-2008 |
20080312295 | Pesticidal Mixtures - Pesticidal mixtures comprising, as active components,
| 12-18-2008 |
20090012130 | Strategies for Designing Drugs that Target the Sir2 Family of Enzymes - The instant invention describes methods of identifying compounds that modulate the activity of Sir2 enzymes. Sir2 enzymes form a unique class Of NAD | 01-08-2009 |
20090054496 | MICROBIOCIDES - The invention relates to a fungicidally active compound of the general Formula (I): where Het is a 5- or 6-membered heterocyclic ring containing one to three heteroatoms, each independently selected from oxygen, nitrogen and sulphur, the ring being substituted by the groups R | 02-26-2009 |
20090076095 | DEUTERIUM-ENRICHED NICORANDIL - The present application describes deuterium-enriched nicorandil, pharmaceutically acceptable salt forms thereof, and methods of treating using the same. | 03-19-2009 |
20090093525 | Cyclopropyl aryl amide derivatives and uses thereof - Compounds of the formula: | 04-09-2009 |
20090105311 | Carboxamides - Use of carboxamides of the formula (I) | 04-23-2009 |
20090118340 | Method for inhibiting and/or preventing formation of cancer metastases and seconddary malignant cancers - The invention relates to a method for inhibiting and/or preventing formation of cancer metastases and secondary malignant cancers by administration to a subject of an effective amount of a quaternary pyridinium salt of formula I | 05-07-2009 |
20090143445 | HDAC Inhibitors - This invention provides the compound having the structure | 06-04-2009 |
20090163558 | Substituted Methyl Aryl or Heteroaryl Amide Compounds - This invention provides a compound of the formula (I): | 06-25-2009 |
20090197924 | 2-AMINO-2-PHENYL-ALKANOL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - 2-amino-2-phenyl-alkanol ester derivatives of general formula (I) in which: R | 08-06-2009 |
20090215838 | ORGANIC NITRIC OXIDE ENHANCING SALTS OF ANGIOTENSIN II ANTAGONISTS, COMPOSITIONS AND METHODS OF USE - The invention describes compositions and kits comprising at least one organic nitric oxide enhancing salt of an angiotensin π antagonist, and, optionally, at least one nitric oxide enhancing compound and/or at least one therapeutic agent. The invention also provides methods for (a) treating cardiovascular diseases; (b) treating renovascular diseases; (c) treating diabetes; (d) treating diseases resulting from oxidative stress; (e) treating endothelial dysfunctions; (f) treating diseases caused by endothelial dysfunctions; (g) treating cirrhosis; (h) treating pre-eclampsia; (j) treating osteoporosis; (k) treating nephropathy; (l) treating peripheral vascular diseases; (m) treating portal hypertension; (n) treating ophthalmic disorders; (o) treating metabolic syndrome; and (p) treating hyperlipidemia. The organic nitric oxide enhancing compounds that form salts with the angiotensin II antagonists are organic nitrates, organic nitrites, nitrosothiols, thionitrites, thionitrates, NONOates, heterocyclic nitric oxide donors and/or nitroxides. The heterocyclic nitric oxide donors are furoxans, sydnonimines, oxatriazole-5-ones and/or oxatriazole-5-imines. | 08-27-2009 |
20090221651 | CHEMICAL PRECONDITIONING AS A PREVENTATIVE OR TREATMENT FOR EXCITOTOXIC SYNAPTIC DAMAGE - A method of preventing HIV-1 associated dendritic pathology in a brain cell, comprising contacting the cell with a therapeutically effective dose of a mitochondrial ATP-sensitive potassium channel agonist. A method of preventing HIV-1 associated dendritic pathology in a brain cell, comprising contacting the cell with a therapeutically effective dose of an inhibitor of succinate dehydrogenase. A method of preventing HIV-1 associated dendritic pathology in a brain cell, comprising contacting the cell with a therapeutically effective dose of a stimulator of production of reactive oxygen species. A model for the study of HIV-1 associated dendritic pathology, comprising a) contacting a hippocampal slice with platelet-activating factor; and b) stimulating the hippocampal slice of a) with high frequency stimulation. | 09-03-2009 |
20090258912 | N-(1-Alkyl-2-Phenylethyl)-Carboxamide Derivatives and Use Thereof as Fungicides - A compound of general formula (I): | 10-15-2009 |
20100004296 | WATERBORNE TOPICAL COMPOSITIONS FOR THE DELIVERY OF AZELAIC ACID - A waterborne topical composition is designed specifically to address the treatment of acne vulgaris, rosacea, seborrheic dermatitis and other skin conditions. The composition contains effective amounts of essential components azelaic acid, niacinamide, and glycerin to create a rapidly penetrating and non-irritating compound. | 01-07-2010 |
20100016377 | Use of a p38 Kinase Inhibitor for Treating Psychiatric Disorders - The use of 6-(S-Cyclopropylcarbamoyl-S-fluoro-2-methyl-phenyl)-N-(2,2-dimethylproyl)-nicotinamide, which is known in the art as a p38 kinase inhibitor in the treatment or prophlaxis of one or more psychiatric disorders. | 01-21-2010 |
20100041715 | SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR ANTAGONISTS AND METHODS FOR USE THEREOF - The invention provides certain well-defined benzamides that are useful as sphingosine-1-phosphate antagonists. As such, the compounds described herein are useful in treating a wide variety of disorders associated with modulation of sphingosine-1-phosphate receptors. | 02-18-2010 |
20100087494 | FUNGICIDE N-(3-PHENYLPROPYL) CARBOXAMIDE DERIVATIVES - A compound of general formula (I): | 04-08-2010 |
20100105742 | PEARLESCENT LIQUID COSMETIC COMPOSITION - A pearlescent liquid cosmetic composition and process for preparation is provided herein. The composition includes 14-25% of a C | 04-29-2010 |
20100120870 | Dispersible pesticidal compositions - Soluble granule pesticidal compositions comprise Flonicamid, a dispersant, and a wetting agent are disclosed. | 05-13-2010 |
20100120871 | HAIR CARE COMPOSITIONS, METHODS, AND ARTICLES OF COMMERCE THAT CAN INCREASE THE APPEARANCE OF THICKER AND FULLER HAIR - Hair care compositions, methods, and articles of commerce that can increase the appearance of thicker and fuller hair. Such compositions can be applied to any areas where a thicker and fuller hair appearance is desired, such as the scalp or face. The present invention also relates to methods of marketing such compositions. | 05-13-2010 |
20100173955 | 4-SUBSTITUTED PHENOXYPHENYLACETIC ACID DERIVATIVES - Compounds of Formula (I): in which R | 07-08-2010 |
20100173956 | Use of Quaternary Pyridinium Salts as Vasoprotective Agents - The invention relates to the use of quaternary pyridinium salts of formula (I), | 07-08-2010 |
20100179198 | Use of homo- and copolymers for stabilizing active ingredient formulations - The present invention relates to the use of specific homo- and copolymers P for the stabilizing of organic active compounds in aqueous compositions or formulations comprising surface-active substances. | 07-15-2010 |
20100197741 | Ternary Fungicidal Compositions Comprising Boscalid and Chlorothalonil - Ternary fungicidal compositions comprising as active components | 08-05-2010 |
20100210695 | COMPOSITIONS AND METHODS FOR TREATING SKIN DISORDERS - The present invention is directed to pharmaceutical compositions formulated for topical administration comprising an inhibitor of carnitine palmitoyl transferase (CPT1) and methods for treating skin disorders, such as psoriasis, by administration of a CPT1 inhibitor. In particular embodiments, the invention provides a pharmaceutical composition formulated for topical administration comprising the CPT1 inhibitor ST1326. In other embodiments, the invention provides a method of treating a skin disorder, such as psoriasis by administration of the CPT1 inhibitor ST1326. | 08-19-2010 |
20100216849 | BIPHENYLCARBOXAMIDES - This invention relates to novel biphenylcarboxamides of the formula (I) | 08-26-2010 |
20100286215 | BIS-AROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION - There is provided compounds of formula (I): wherein Y, ring A, D | 11-11-2010 |
20100324101 | Use of Succinate Dehydrogenase Inhibitors for Increasing the Resistance of Plants or Parts of Plants to Abiotic Stress - The invention relates to the use of succinate dehydrogenase inhibitors, in particular bixafen, for increasing the resistance of plants to abiotic stress factors, to a method for treating plants or parts of plants for increasing the resistance to abiotic stress factors and to a method for increasing the resistance of seed and germinating plants to abiotic stress factors by treating the seed with a succinate dehydrogenase inhibitor. | 12-23-2010 |
20100331377 | COMPOSITIONS AND METHODS FOR WOUND CARE - The present disclosure relates to compositions for and methods of repairing the stratum corneum, compositions and methods for inhibiting excessive transepidermal water loss, compositions for and methods of treating skin that is distressed or wounded as a result of a disease or other biological condition or process (as distinguished from wounds resulting from trauma), compositions for and methods of treating chronic wounds, and compositions for the inhibition and treatment of necrosis and extended quiescence that result in cellular necrosis instead of normal proliferation | 12-30-2010 |
20110009457 | Aminobenzamide Derivatives as Useful Agents for Controlling Animal Parasistes - The invention relates to a composition comprising at least one aminobenzamide compound or a salt thereof for controlling animal parasites, veterinary pharmaceutical compositions comprising at least one aminobenzamide of formula (I) for preventing infection with diseases transmitted through parasites, its use for the preparation of a veterinary pharmaceutical for controlling animal parasites, and a method for preventing infection with diseases transmitted through parasites. | 01-13-2011 |
20110028521 | PESTICIDAL COMPOSITION, AND METHOD FOR CONTROLLING PESTS - To provide a pesticidal composition having a stable and high pesticidal effect. The pesticidal composition comprises a pyridine compound represented by the formula (I): | 02-03-2011 |
20110039898 | METHOD FOR SCAVENGING FREE RADICALS AND INHIBITING TYROSINASE AND MELANIN - A method for scavenging free radicals and inhibiting tyrosinase and melanin is provided. The method includes administering to a subject of effective amounts in a pharmaceutical composition comprising a compound of Formula (I) or (II) and a pharmaceutical acceptable salt, metal salt or solvent. | 02-17-2011 |
20110053990 | FATTY ACID NIACIN CONJUGATES AND THEIR USES - The invention relates to fatty acid niacin conjugates; compositions comprising an effective amount of a fatty acid niacin conjugate; and methods for treating or preventing an metabolic disease comprising the administration of an effective amount of a fatty acid niacin conjugate. | 03-03-2011 |
20110082177 | N'-NITROXYALKYLNICOTINAMIDES FOR THE TREATMENT OF CARDIOVASCULAR DISEASES - The invention relates to the novel N′-nitroxyalkylnicotinamide derivatives represented by the general formula I wherein R | 04-07-2011 |
20110196000 | Use of succinate dehydrogenase (SDH) inhibitors in the treatment of plant species from the family of the true grasses - The use is described of at least one succinate dehydrogenase (SDH) inhibitor for increasing the biomass of the flag leaf, of leaf F-1 and/or of leaf F-2 of the plant of plant species from the family of the true grasses (Poaceae). | 08-11-2011 |
20110201653 | METHOD FOR INHIBITING AND/OR PREVENTING FORMATION OF CANCER METASTASES AND SECONDARY MALIGNANT CANCER - The invention relates to a method for inhibiting and/or preventing formation of cancer metastases and secondary malignant cancers by administration to a subject of an effective amount of a quaternary pyridinium salt of formula I | 08-18-2011 |
20110213002 | MACROCYCLIC DITERPENES FOR TREATING CONDITIONS ASSOCIATED WITH PROTEIN KINASE C - The present invention relates generally to chemical agents useful in the treatment and prophylaxis of inflammatory conditions or in the amelioration of symptoms resulting from or facilitated by an inflammatory condition in a mammalian animal including human and primate, non-mammalian animal and avian species. More particularly, the present invention provides a chemical agent of the macrocyclic diterpene family obtaining from a member of the Euphorbiaceae family of plants or botanical or horticultural relatives thereof or derivatives or chemical analogues or chemically synthetic forms of the agents for use in the treatment or prophylaxis of an inflammatory condition or in the amelioration of symptoms resulting from or facilitated by an inflammatory condition in a mammal, animal or avian species. The present invention further contemplates a method for the prophylaxis or treatment of mammalian, animal or avian subjects for inflammatory conditions including chronic or transitory inflammatory conditions or for ameliorating the symptoms of an inflammatory condition by the topical or systemic administration of a macrocyclic diterpene obtainable from a member of the Euphorbiaceae family or botanical or horticultural relatives thereof or a derivative, chemical analogue or chemically synthetic form of the agent. The chemical agent of the present invention may be in the form of a purified compound, mixture of compounds, a precursor form of one or more of the compounds capable of chemical transformation into a therapeutically active agent or be in the form of a chemical fraction, sub-fraction or preparation or extract of the plant. | 09-01-2011 |
20110245297 | Use Quaternary Pyridinium Salts as Vasoprotective Agents - The invention relates to the use of quaternary pyridinium salts of formula (I), | 10-06-2011 |
20110263659 | Analogs of 1-Methylnicotinamide - The present invention is directed to derivatives and analogs of 1-methyl-nicotinamide useful for elevating the blood levels of 1-methylnicotinamide or deuterated species in a subject. | 10-27-2011 |
20110269802 | METHOD OF DELIVERY OF PERISHABLE LIQUID MIXTURES USING MIXING CAP AND CONTAINER SYSTEM - Methods for preparing and delivering perishable liquid mixtures comprising at least one active ingredient. The methods use systems comprising vessels having novel barriers for segregating solvent liquids from active ingredients prior to preparation. Novel liquid mixtures having therapeutic properties are also disclosed. | 11-03-2011 |
20120046323 | Use of Succinate Dehydrogenase Inhibitors and/or Respiratory Chain Complex III Inhibitors for Improving the Ratio of Harmful to Beneficial Microorganisms - The present invention relates to the use of succinate dehydrogenase inhibitors and/or complex III inhibitors for controlling undesired fungal pathogens and simultaneously improving the ratio of harmful to beneficial microorganisms in crops and to a method for treating crops or parts of crops for controlling undesired fungal pathogens and simultaneously improving the ratio of harmful to beneficial microorganisms by treating the crops or parts of crops with a succinate dehydrogenase inhibitor and/or a complex III inhibitor. | 02-23-2012 |
20120095063 | METHODS AND COMPOSITIONS FOR TREATMENT OF ISCHEMIC CONDITIONS AND CONDITIONS RELATED TO MITOCHONDRIAL FUNCTION - The present invention relates to compositions and methods for prophylactic and/or therapeutic treatment of conditions related to mitochondrial function. In various aspects, the present invention comprises administering one or more compounds selected from the group consisting of epicatechin, an epicatechin derivative, catechin, a catechin derivative, nicorandil, and a nicorandil derivative in an amount effective to stimulate mitochondrial function in cells. The methods and compositions described herein provide for reducing infarct size in the heart following permanent ischemia or ischemia/reperfusion (IR) event or method for delaying, attenuating or preventing adverse cardiac remodeling, and can assist in prevention of impaired mitochondria biogenesis and thus prevention of the consequences of impaired mitochondrial biogenesis in various diseases and conditions, as well as provide for the active therapy of mitochondrial depletion that may have already occurred. | 04-19-2012 |
20120122935 | COMPOSITIONS AND METHODS FOR TREATING NECROTIZING ENTEROCOLITIS - The present invention relates to a method for treating or preventing necrotizing enterocolitis (NEC) in a human neonate in need thereof, comprising administering to the neonate a pharmaceutically effective amount of a composition comprising a poly(ADP-ribose) synthetase/polymerase (PARP) inhibitor. Also contemplated herein is an infant food or treatment composition comprising a PARP inhibitor in an amount that is 5 to 500 times greater than a daily recommended intake dosage for the PARP inhibitor. | 05-17-2012 |
20120142744 | NOVEL COMPLEXES OF FATTY ACID ESTERS OF POLYHYDROXYALKANES AND PYRIDINE CARBOXY DERIVATIVES - The present invention relates to novel combinations of fatty acid derivatives and pyridine carboxy derivatives, including fatty acid esters with glycerol and 3-carboxy pyridine derivates such as niacinamide. Such combinations have surprisingly shown antiviral and anti-microbial activity and the use for the treatment of inflammatory conditions and infections is disclosed herein. | 06-07-2012 |
20120184585 | FATTY ACID NIACIN CONJUGATES AND THEIR USES - The invention relates to fatty acid niacin conjugates; compositions comprising an effective amount of a fatty acid niacin conjugate; and methods for treating or preventing an metabolic disease comprising the administration of an effective amount of a fatty acid niacin conjugate. | 07-19-2012 |
20120214851 | Aminobenzamide Derivatives as Useful Agents for Controlling Animal Parasites - The invention relates to a composition comprising at least one aminobenzamide compound or a salt thereof for controlling animal parasites, veterinary pharmaceutical compositions comprising at least one aminobenzamide of formula (I) for preventing infection with diseases transmitted through parasites, its use for the preparation of a veterinary pharmaceutical for controlling animal parasites, and a method for preventing infection with diseases transmitted through parasites. | 08-23-2012 |
20120252850 | NIACIN CONJUGATED FATTY ACID MIXTURES AND THEIR USES - The invention relates to niacin conjugated fatty acid mixtures; compositions comprising an effective amount of a niacin conjugated fatty acid mixture; and methods for treating or preventing an metabolic disorder comprising the administration of an effective amount of a niacin conjugated fatty acid mixture. | 10-04-2012 |
20120258989 | USE OF SUCCINATE DEHYDROGENASE INHIBITORS FOR EXTENDING SHELF LIFE OF FRUITS AND VEGETABLES - The present invention relates to the use of succinate dehydrogenase Inhibitors for extending shelf life and storage stability of fruits and vegetables, to a method for extending shelf life of fruits and vegetables by applying a succinate dehydrogenase inhibitor to the crops prior to the harvest of the fruits or vegetables and to a fruit or vegetable treated with a succinate dehydrogenase Inhibitor. | 10-11-2012 |
20120264791 | FATTY ACID NIACIN CONJUGATES AND THEIR USES - The invention relates to fatty acid niacin conjugates; compositions comprising an effective amount of a fatty acid niacin conjugate; and methods for treating or preventing an metabolic disease comprising the administration of an effective amount of a fatty acid niacin conjugate. | 10-18-2012 |
20130035359 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS - Disclosed are pharmaceutical and cosmetic compositions containing aromatic aldehyde compounds. Some of the disclosed compositions are useful as topical therapeutics for treating inflammatory dermatologic conditions. Some of the compositions are useful in transdermal and other systemic dose forms for treating other inflammatory conditions in mammals. | 02-07-2013 |
20130040998 | FLUORINATED HDAC INHIBITORS AND USES THEREOF - Fluorinated deacetylase inhibitors of the general formulae (I), (II), and (III): and pharmaceutically acceptable salts thereof, as described herein, are useful as inhibitors of histone deacetylases or other deacetylases, and thus are useful for the treatment of various diseases and disorders associated with acetylase activity as described herein (e.g., cancer, neurodegenerative diseases, inflammatory diseases). | 02-14-2013 |
20130131124 | O-CYCLOPROPYLCYCLOHEXYL-CARBOXANILIDES AND THEIR USE AS FUNGICIDES - The present invention relates to O-CYCLOPROPYLCYCLOHEXYL-CARBOXANILIDES derivatives of formula (I); their process of preparation, their use as fungicide, particularly in the form of fungicide compositions, and methods for the control of phytopathogenic fungi, notably of plants, using these compounds or compositions. | 05-23-2013 |
20130253014 | Cyclodextrin-Based Microemulsions, and Dermatological Uses Thereof - Described herein are cyclodextrin-stabilized microemulsion systems useful for increasing the solubility, stability, bioavailability, or safety of an active agent for delivery to the skin. The microemulsions may reduce the occurrence of skin irritation or odor upon application. | 09-26-2013 |
20130253015 | Cyclodextrin-Based Microemulsions, and Dermatological Uses Thereof - Described herein are cyclodextrin-stabilized microemulsion systems useful for increasing the solubility, stability, bioavailability, or safety of an active agent for delivery to the skin. The microemulsions may reduce the occurrence of skin irritation or odor upon application. In certain embodiments, the active agent is substantially insoluble in water. | 09-26-2013 |
20130253016 | SYNERGISTIC PARAFFINIC OIL AND BOSCALID FUNGICIDES - Fungicidal compositions comprising a paraffinic oil and 2-chloro-N-(4′-chloro[1,1′-biphenyl]-2-yl)-3-pyridinecarboxamide (boscalid) are provided. The fungicidal compositions may further comprise a pigment. The fungicidal compositions may be provided as oil-in-water (O/W) emulsions which may be used for controlling fungal disease, such as dollar spot or bentgrass dead spot or bermudagrass dead spot, in plants, such as turfgrasses. Methods of applying the fungicidal compositions are also provided. | 09-26-2013 |
20130296383 | DECAHYDRO-1,4-METHANONAPHTHALEN CARBOXAMIDES - The present invention relates to decahydro-1,4-methanonaphthalen carboxamide derivatives of formula (Ia) or (Ib); their process of preparation, their use as fungicide, particularly in the form of fungicide compositions, and methods for the control of phytopathogenic fungi, notably of plants, using these compounds or compositions. | 11-07-2013 |
20140039016 | METHOD OF EMPLOYING ENHANCED PENETRATION OF WOOD PRESERVATIVES TO PROTECT WOOD AND A RELATED SOLUTION - A method of protecting wood through enhanced penetration of wood preservatives includes providing a solution including (a) at least one amine oxide, (b) at least one organic wood preservative and (c) a non-borate buffering based agent. The solution has a pH of 5 to 12.4 and preferably about 7 to 10. The solution is applied to the surface of the wood after which, with or without intervening storage, the materials are activated to effect enhanced penetration of the organic wood preservative into the wood. One may effect application at a solution temperature of about 30° C. to 75° C. and preferably about 50° C. to 60° C. to effect activation at a higher temperature and high relative humidity. In a preferred practice, the wood may be heated before and/or after application of the solution. The solution is also disclosed as a product. | 02-06-2014 |
20140073674 | COCRYSTALS OF P-COUMARIC ACID - Disclosed herein are cocrystals of p-coumaric acid and nicotinamide. A 1:1 molar ratio and a 2:1 molar ratio of p-coumaric acid to nicotinamide are herein disclosed. | 03-13-2014 |
20140088161 | USE OF A FEED COMPOSITION FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE - The present invention relates to the field of reduction of methane emission in ruminants. Particularly, it relates to the use of a feed composition or a feed additive comprising at least one antibiotic and at least one organic molecule substituted at any position with at least one nitrooxy group for reducing the production of methane emanating from the digestive activities of ruminants, and/or to improve the ruminant performance. | 03-27-2014 |
20140187591 | SOLID FORM AND METHOD FOR PREPARING THE SAME - The disclosure provides a solid form and a method for preparing the same. The solid form consists essentially of a biodegradable copolymer and an amide-containing compound. The biodegradable copolymer is semi-crystalline due to the dipole-dipole interaction between the biodegradable copolymer and the urea. The method for preparing the above solid form includes: dissolving a biodegradable copolymer and an amide-containing compound in water at a first temperature, obtaining a solution; cooling the solution at a second temperature to form a solid mixture; and the solid mixture is subjected to a freeze-drying process at a third temperature. | 07-03-2014 |
20140296305 | Use of Quaternary Pyridinium Salts as Vasoprotective Agents - The invention relates to the use of quaternary pyridinium salts of formula (I), | 10-02-2014 |
20140315959 | TREATMENT OF OVARIAN CANCER WITH BENZYLIDENEBENZOHYDRAZIDES - Methods for inhibiting the growth of ovarian cancer cells or other serosal cancer cells are disclosed. The method involves exposing the cells to a benzylidinebenzohydrazide of formula: | 10-23-2014 |
20140323528 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES - The present invention relates to novel triazole derivatives of formula (I) having insecticidal activity, to processes and intermediates for preparing them, to insecticidal, acaricidal, nematicidal or molluscicidal compositions comprising them and to methods of using them to combat and control insect, acarine, nematode or mollusc pests wherein R | 10-30-2014 |
20140343108 | OLEANOLIC ACID AMIDATE DERIVATIVES, PREPARATION METHODS AND USES THEREOF - The present invention belongs to the field of natural medicine and pharmaceutical chemistry, and specifically relates to novel amidated derivatives of oleanolic acid according to formula (I) or a pharmaceutically acceptable salt thereof, to a process for the preparation of these compounds, compositions containing such compounds and their use in preparing antineoplastic medicaments. | 11-20-2014 |
20140357679 | ACTIVE COMPOUND COMBINATIONS - The present invention relates to compositions, in particular within a fungicide composition, which comprises (A) a dithiino-tetracarboximide of formula (I) and a further fungicidally active compound (B). Moreover, the invention relates to a method for curatively or preventively controlling the phytopathogenic fungi of plants or crops, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and to the treated seed. | 12-04-2014 |
20150025117 | USE OF SUCCINATE DEHYDROGENASE INHIBITORS FOR CONTROLLING POWDERY MILDEW PRIMARY INFECTIONS - The present invention relates to the use of succinate dehydrogenase Inhibitors for controlling powdery mildew primary infections in crops and to a method for controlling those primary infections. | 01-22-2015 |
20150119427 | WATERBORNE TOPICAL COMPOSITIONS FOR THE DELIVERY OF AZELAIC ACID FOR TREATMENT OF SKIN CONDITIONS SUCH AS ACNE VULGARIS, ROSACEA, SEBORRHEIC DERMATITIS - A waterborne topical composition is designed specifically to address the treatment of acne vulgaris, rosacea, seborrheic dermatitis and other skin conditions. One composition contains effective amounts of essential components azelaic acid, niacinamide, and glycerin to create a rapidly penetrating and non-irritating compound. One composition contains effective amounts of essential components azelaic acid, niacinamide, and cyclodextran to create a rapidly penetrating and non-irritating compound. | 04-30-2015 |
20150119428 | TRANILAST COMPOSITIONS AND COCRYSTALS - Mew tranilast complexes and new tranilast cocrystals are disclosed. These include all tranilast nicotinamide complex, a 1:1 tranilast nicotinamide cocrystal, a 1:1 tranilast saccharin complex, a 1:1 tranilast saccharin cocrystal, a 1:1 tranilast gentisic acid complex, a 1:1 tranilast gentisic acid cocrystal, a 1:1 tranilast salicylic acid complex, a 1:1 tranilast salicylic acid cocrystal, a 1:1 tranilast urea complex, a 1:1 tranilast urea cocrystal, a 1:1 tranilast 4-amtnoben2oic acid complex, a 1:1 tranilast 4-am!nobers2oic acid cocrystal, a 1:1 tranilast 2,4-di′hydroxybenzoic acid complex and a 1:1 tranilast 2,4-dihydroxybenzoic acid cocrystal. Also disclosed are pharmaceutical compositions containing a tranilast complex or cocrystal of the invention and a pharmaceutically acceptable carrier. Methods of treatment using the tranilast complexes and cocrystais as well as the pharmaceutical compositions are disclosed. | 04-30-2015 |
20150133508 | Use of Quaternary Pyridinium Salts as Vasoprotective Agents - The invention relates to the use of quaternary pyridinium salts of formula (I), | 05-14-2015 |
20150148383 | Methods for Inhibiting or Reversing Epiretinal Membrane Formation - Described herein are treatment methods involving the administration of nicotinamide, which has been discovered to stabilize the normal phenotype of retinal pigment epithelial cells and to prevent retinal pigment epithelial cell proliferation. Diseases and disorders that can be treated according to the methods disclosed herein include, e.g., macular pucker, proliferative vitreoretinopathy, preretinal fibrosis, vitreomacular traction, tractional retinal detachment, and phthsis bulbi, cystoid macular edema (CME) arising from intraocular inflammation due to uveitis, vasculitis, trauma, surgery, and collagen vascular disease (e.g., Behcets disease or sarcoidosis), and age related macular degeneration. | 05-28-2015 |
20150296771 | OIL-BASED PESTICIDAL SUSPENSION - To provide an oil-based pesticidal suspension which suppresses foaming at the time of preparation of a spray liquid by an organic silicone type surfactant, and which has excellent pesticidal activity with a small amount of an agricultural chemical. | 10-22-2015 |
20150336896 | DIFLUOROMETHYL-NICOTINIC- TETRAHYDRONAPHTHYL CARBOXAMIDES AS FUNGICIDES - The present invention relates to novel difluoromethyl-nicotinic indanyl carboxamides, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as | 11-26-2015 |
20150368221 | CYCLOALKENYL HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS HISTONE DEACETYLASE INHIBITORS - The present invention provides compounds of formula (I) or a pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein W, X, n, s, t, and Ra are as described herein. The present invention relates generally to selective inhibitors of histone deacetylase and to methods of making and using them. | 12-24-2015 |
20150376113 | USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE - The present invention relates to a method for reducing the production of methane emanating from the digestive activities of a ruminant and/or for improving ruminant animal performance by using, as active compound at least one organic molecule substituted at any position with at least one nitrooxy group, or a salt thereof, which is administrated to the animal together with the feed. The invention also relates to the use of these compounds in feed and feed additives such as premix, concentrates and total mixed ration (TMR) or in the form of a bolus. | 12-31-2015 |
20160029623 | INSECTICIDAL COMPOUNDS - The present invention relates to novel triazole derivatives of formula (I) having insecticidal activity, to processes and intermediates for preparing them, to insecticidal, acaricidal, nematicidal or molluscicidal compositions comprising them and to methods of using them to combat and control insect, acarine, nematode or mollusc pests wherein R | 02-04-2016 |
20160075653 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES - The present invention relates to the use of N-(Phenylcycloalkyl)carboxamides and N-(Phenylcycloalkyl)thiocarboxamides for the control of nematodes in agriculture and as anthelmintic agents against endoparasites in animals and humans, compositions containing such compounds and methods for the control of nematodes and helminths and furthermore to novel N-(Phenylcycloalkyl)carboxamides and N-(Phenylcycloalkyl)thiocarboxamides, processes and intermediate compounds for their preparation, their use as nematicides, compositions containing such compounds and methods for the control of nematodes. | 03-17-2016 |
20160101080 | ASSAYS, METHODS AND MEANS - A novel class of hydroxylases is described having the amino acid sequence of SEQ ID NO: 2, 4, 6 and 8, and variants and fragments thereof having HIF hydroxylation activity. The polypeptides of the invention have in particular prolyl hydroxylase activity. An assay method monitors the interaction of the IIIF hydroxylase with a substrate. Modulators of IIIF hydroxylase are provided for use in the treatment of a condition associated with increased or decreased HIF levels or activity or for the treatment of a condition where it is desirable to modulate HIF levels or activity. | 04-14-2016 |
20160101094 | ASSAYS, METHODS AND MEANS - A novel class of hydroxylases is described having the amino acid sequence of SEQ ID NO: 2, 4, 6 and 8, and variants and fragments thereof having HIF hydroxylation activity. The polypeptides of the invention have in particular prolyl hydroxylase activity. An assay method monitors the interaction of the IIIF hydroxylase with a substrate. Modulators of IIIF hydroxylase are provided for use in the treatment of a condition associated with increased or decreased HIF levels or activity or for the treatment of a condition where it is desirable to modulate HIF levels or activity. | 04-14-2016 |
20160136076 | RETINOID DERIVATIVES AND PROCESS FOR THEIR PREPARATION - Novel retinoic acid derivatives and a process for their preparation are described. | 05-19-2016 |
20160150783 | SYNERGISTIC PARAFFINIC OIL AND BOSCALID FUNGICIDES | 06-02-2016 |
20160157485 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES - Compounds of the formula (I), in which the substituents are as defined in claim | 06-09-2016 |
20160184289 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS - Disclosed are pharmaceutical and cosmetic compositions containing aromatic aldehyde compounds. Some of the disclosed compositions are useful as topical therapeutics for treating inflammatory dermatologic conditions. Some of the compositions are useful in transdermal and other systemic dose forms for treating other inflammatory conditions in mammals. | 06-30-2016 |
20160250116 | METHOD FOR CONDITIONING THE SCALP TO RESIST DANDRUFF | 09-01-2016 |
20160376303 | GLYCYRRHETINIC ACID DERIVATIVE AND USE THEREOF - A novel glycyrrhetinic acid derivative. The glycyrrhetinic acid derivative is represented by the following general formula. | 12-29-2016 |