| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 514295000 | Two of the cyclos share at least three ring carbons (i.e., bridged) (e.g., benzomorphans, etc.) | 14 |
| 20080234311 | IMMUNOASSAY FOR DETECTION AND QUANTIFICATION OF AMYLOID-beta PEPTIDES - The present invention provides a method for the detection and quantification of Aβ | 09-25-2008 |
| 20080312268 | Substituted tricyclic piperidone compounds - Substituted tricyclic piperidone derivatives corresponding to Formula I: | 12-18-2008 |
| 20090030032 | Bicyclic Compound, Production and Use Thereof - The present invention provides a new cyclic compound having a CCR antagonist activity, especially a CCR5 antagonist activity, and the use thereof. The compound of the present invention is represented by the formula: | 01-29-2009 |
| 20090118320 | DERIVATIVES OF 5,9-METHANOCYCLOOCTA[B]PYRIDIN-2-(1H)-ONE, THEIR PREPARATION AND USE AS ANALGESICS - A compound of Formula I, a pharmaceutically-acceptable salt or a hydrate thereof, wherein R | 05-07-2009 |
| 20100130537 | CINNAMIDE COMPOUNDS FOR DEMENTIA - The invention provides methods for treating, preventing, and delaying the onset of dementia and mild cognitive impairments by administering to a patient in need thereof at least one cinnamide compound and one or more second-line active ingredients, such as cholinesterase inhibitors; AMPA receptor antagonists; NMDA receptor antagonists; and the like. The invention also provides pharmaceutical compositions, combinations, and kits. | 05-27-2010 |
| 20100234416 | USE OF HUPERZINE FOR DISORDERS - Methods and compositions containing huperzine are used to prevent and alleviate neuropathic pain. The invention is also directed to methods and compositions for using huperzine for the prevention and/or treatment of neuropathic pain and orthostatic hypotension. | 09-16-2010 |
| 20100324080 | Benzomorphan Compounds - The invention relates to Benzomorphan Compounds of Formula (I): wherein X, R | 12-23-2010 |
| 20110237618 | METHODS FOR TREATING MIGRAINES WITH HUPERZINE A DERIVATIVES - The present invention relates to a method for treating, alleviating, or preventing pain, particularly migraines, functional pain syndrome, or organic pain syndrome, by administering to a patient in need thereof compound (I), or salts thereof, or pharmaceutical preparations thereof comprising mixtures of compound (I) or salts thereof with pharmaceutically-acceptable diluents | 09-29-2011 |
| 20110269791 | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use - The present invention relates to compounds defined by Formula (I), wherein the groups A, B, X, m, n and o are defined as in claim | 11-03-2011 |
| 20130040982 | ORAL SUSTAINED RELEASE FORMULATION OF HUPERZINE A - Sustained-release formulations comprising huperzine A are disclosed herein. The formulations are for oral administration, and contain a carrier which comprises native albumin. Unit dosage forms of the formulations, and kits comprising such unit dosage forms are also disclosed herein. Methods utilizing the formulations for treating a medical condition treatable by huperzine A are also disclosed herein, as well as processes for preparing the formulations, and uses of huperzine A and albumin in the manufacture of a medicament. | 02-14-2013 |
| 20140066475 | Method For Treating Pruritus - Benzomorphan compounds are found to be useful for treating, ameliorating or preventing pruritus, and in particular pruritus associated with (including induced by) the administration of opioids. Antipruritic activity is believed to be mediated through the dual action of the compounds as mu opioid receptor antagonists and kappa opioid receptor agonists. Pharmaceutical compositions contain therapeutically effective amounts of these useful compounds, optionally in combination with second therapeutic agents, such as opioid or non-opioid analgesics or other compounds. | 03-06-2014 |
| 20140221419 | BENZOMORPHAN ANALOGS AND THE USE THEREOF - The present invention is directed to Benzomorphan Analog compounds of the Formula I-ID as shown below, wherein R | 08-07-2014 |
| 20150335624 | COMPOSITIONS AND METHODS FOR USING HUPERZINE AND ANALOGS THEREOF - A method of treating a seizure disorder is described wherein an acetylcholinesterase(AChE) inhibitor is administered to a subject having a seizure disorder and an increased risk of a cardiac event from the seizure disorder, wherein the AChE inhibitor decreases the risk of such cardiac event. Further described are methods of decreasing the risk of a cardiac event in subjects with or without a seizure disorder by administering a therapeutically effective amount of an AChE inhibitor. Methods of treating kidney disease and reducing an elevated CRP level by administering an AChE inhibitor are also described. | 11-26-2015 |
| 20160083351 | TETRAHYDROISOQUINOLINES AS SELECTIVE NADPH OXIDASE 2 INHIBITORS - Embodiments of bridged tetrahydroisoquinolines and methods for their use in selectively inhibiting nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 2 are disclosed. The disclosed compounds have a structure according to general formula I or a pharmaceutically acceptable salt thereof: | 03-24-2016 |
