Class / Patent application number | Description | Number of patent applications / Date published |
514251000 | Isoalloxazine (e.g., riboflavins, Vitamin B2, etc.) | 13 |
20090054443 | COMPOSITIONS CONTAINING RIBOFLAVIN AND SESAMIN-CLASS COMPOUNDS - The present invention relates to a composition containing riboflavin and a sesamin-class compound(s). This composition may incorporate a sesamin-class compound(s) in such an amount that the proportion (weight ratio) of its total quantity to the total quantity of riboflavin taken as unity is no more than 4.5, and it has the advantage that the analgesic and anti-fatigue actions of riboflavin are synergistically improved by ingestion of riboflavin in combination with a sesamin-class compound(s). | 02-26-2009 |
20090176792 | SUBSTITUTED DIBENZHYDRYLPIPERAZINES - The present invention relates to new dibenzhydrylpiperazine modulators of histamine receptors, pharmaceutical compositions thereof, and methods of use thereof. | 07-09-2009 |
20100035888 | Diaryl Urea for Treating Pulmonary Hypertension - The present invention relates to pharmaceutical compositions for treating, preventing or managing pulmonary hypertension comprising 4{4-[3-(4-chloro-3-trifluoromethylphenyl)-ureido]-3-fluorophenoxy}-pyridine-2-carboxylic acid methylamide optionally combined with at least one additional therapeutic agent. | 02-11-2010 |
20100144746 | METHOD FOR RESTRUCTURING A BIOLOGICAL TISSUE COMPRISING COLLAGEN FIBRILS AND RELATIVE USES - A method for restructuring a biological tissue comprising collagen fibrils selected from a venous tissue, a cardiac valvular tissue, a cutaneous or subcutaneous tissue, a tissue of a muscular tendon, a tissue of a muscular fascia or a tissue of a muscular aponeurosis, comprising the following operational steps: a) bringing into contact a biological tissue comprising collagen fibrils with a cross-linking chemical composition able to induce cross-linking of collagen fibrils consequent to activation through electromagnetic radiation; b) activating said cross linking chemical composition through exposure to an electromagnetic radiation; c) cross-linking the collagen fibrils of said biological tissue in order to obtain a restructured biological tissue. The method according to the invention can be applied to recover a venous continence and both a venous and a cardiac valve diameter. The method reduces the visibility of cutaneous wrinkles, reinforces or repairs tendons, muscular fascia and aponeurosis as well as to heals surgical or traumatic cutaneous wounds or cutaneous ulcers. | 06-10-2010 |
20100286156 | Collyrium For The Treatment Of Conical Cornea With Cross-Linking Trans-Epithelial Technique - A collyrium for the treatment of patients suffering from conical cornea contains a riboflavin photosensitizing substance and a surface-active agent to assist penetration of the collyrium into the corneal epithelium. The collyrium does not require removal of the corneal epithelium, with the absence of pain for the patient, who does not need post treatment therapy, and who no longer complains of edema due to the prior art removal of the epithelium, thereby preserving the original corneal transparency. | 11-11-2010 |
20110306617 | Methods and Compositions for the Production of High Concentration Alloxazine Solutions - Methods are provided for preparation of compositions having an enhanced level of soluble alloxazine, as compared to compositions prepared using conventional techniques. Compositions and a riboflavin form having higher solubility in solution is also provided. | 12-15-2011 |
20130029998 | Method of Detecting and Profiling Progression of the Risk of Neurodegenerative Diseases - The present invention generally relates to methods of detecting and profiling progression of the risk of neurodegenerative diseases in a subject. In one embodiment, the method includes isolating a stem cell from cerebrospinal fluid of the subject and determining the level of H3K27 methylation within the stem cell. The subject is determined to have an increased risk of developing the neurodegenerative disease if the level of H3K27 methylation is elevated. In various embodiments, the neurodegenerative disease is Alzheimer's Disease, Parkinson's Disease or Amyotrophic Lateral Sclerosis. | 01-31-2013 |
20130261127 | COMPOSITION FOR ENHANCING ATHLETIC PERFORMANCE - A composition can include a plurality of active ingredients such as pyruvate, niacin, riboflavin, lipoic acid, and amidated glycine. The concentration by weight of the first active ingredient (pyruvate) in the composition can be greater than the concentration by weight of each one of the other active ingredients. The composition can affect ATP and Krebs efficiency when ingested by an animal. | 10-03-2013 |
20130267528 | TRANS-EPITHELIAL OSMOTIC COLLYRIUM FOR THE TREATMENT OF KERATOCONUS - Trans-epithelial osmotic collyrium for the treatment of keratoconus by corneal cross-linking with UV rays, of the type consisting of a riboflavin-based solution and an absorption enhancement adjuvant consisting of benzalkonium chloryde (BAC). The solution has a hypoosmolarity degree ranging between −70% and −30% over an isotonic solution and contains a BAC concentration accordingly ranging between 0.005% and 0.035%. | 10-10-2013 |
20140128403 | USE OF 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES - Use of 10H-benzo[g]pteridine-2,4-dione derivatives as photosensitizers in the inactivation of microorganisms. | 05-08-2014 |
20140200220 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF - The present disclosure relates to 10H-benzo[g]pteridine-2,4-dione derivatives, to the production thereof, and to the use thereof. | 07-17-2014 |
20140303173 | CROSS-LINKING COMPOSITION DELIVERED BY IONTOPHORESIS, USEFUL FOR THE TREATMENT OF KERATOCONUS - An improved formulation of an ophthalmic composition contains riboflavin, as cross-linking agent of corneal collagen, administered by corneal iontophoresis, able to guarantee an increased capacity of permeation of riboflavin of the corneal stroma and therefore greater therapeutic efficacy in the treatment of keratoconus. | 10-09-2014 |
20150080407 | COMPOSITIONS CONTAINING RIBOFLAVIN AND SESAMIN-CLASS COMPOUNDS - The present invention relates to a composition containing riboflavin and a sesamin-class compound(s). This composition may incorporate a sesamin-class compound (s) in such an amount that the proportion (weight ratio) of its total quantity to the total quantity of riboflavin taken as unity is no more than 4.5, and it has the advantage that the analgesic and anti-fatigue actions of riboflavin are synergistically improved by ingestion of riboflavin in combination with a sesamin-class compound(s). | 03-19-2015 |