| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 514188000 | Hetero ring is six-membered consisting of one nitrogen and five carbons | 80 |
| 20080255082 | Hair and/or Scalp Care Compositions Incorporating Terpenoid Compounds - The invention provides a hair and/or scalp care composition comprising a terpenoid compound of formula (I), (II) or (III) in which R | 10-16-2008 |
| 20090036418 | Pharmaceutical composition for treatment of cancer containing pyridylpyridazine or transition metal complex thereof as active ingredient - The present invention relates to a pharmaceutical composition for the treatment of cancer, which contains, as an active ingredient, a pyridylpyridazine compound or a transition metal complex thereof. | 02-05-2009 |
| 20090156570 | Synergistic biocide composition comprising 2-methylisothiazoline-3-one - A biocide composition, comprising 2-methylisothiazolin-3-one as a biocidal active ingredient and at least one further biocidal active ingredient, as an additive to materials capable of being attacked by harmful microorganisms, wherein the composition comprises a pyrithione as the further biocidal active ingredient. | 06-18-2009 |
| 20090163461 | Ligand for Vesicular Acetylcholine Transporter - The present invention provides a novel compound represented by the formula (I): | 06-25-2009 |
| 20090197854 | USE OF PICOPLATIN TO TREAT COLORECTAL CANCER - The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment regimens. Dosages, dosing schedules, and ancillary treatments are described. | 08-06-2009 |
| 20090209509 | WATER-SOLUBLE ZINC IONOPHORES, ZINC CHELATORS, AND/OR ZINC COMPLEXES AND USE FOR TREATING CANCER - Disclosed herein are novel zinc ionophores, zinc chelators and/or zinc complexes with enhanced aqueous solubility. Methods of treating cancer using at least one zinc ionophore and/or zinc chelator are also disclosed. Also disclosed herein are compositions and methods for treating cancer with combination therapy using at least one texaphyrin metal complex and at least one zinc ionophore or the respective pharmaceutically acceptable derivatives or salts thereof. | 08-20-2009 |
| 20090215739 | Chemical method of making a suspension, emulsion or dispersion of pyrithione particles - A method for producing a suspension, emulsion or dispersion of de-agglomerated particles (advantageously submicron-sized particles) of pyrithione salts comprising contacting agglomerated pyrithione salt particles with a de-agglomerating agent to produce the desired de-agglomerated pyrithione salt particles. Also disclosed is a method for making de-agglomerated submicron-sized particles of pyrithione salts comprising a heating step. Also disclosed are the particles made by the above methods and compositions comprising the particles and a base medium. | 08-27-2009 |
| 20090233894 | Compounds and Methods For The Treatment of Cancer - The present invention provides organic arsenicals which may be used to treat numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant blood cells from patients with leukemia. | 09-17-2009 |
| 20090275549 | USE OF PICOPLATIN TO TREAT COLORECTAL CANCER - The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment regimens. | 11-05-2009 |
| 20090298805 | TOPICAL PYRITHIONE COMPOSITIONS AND METHODS FOR TREATMENT OF NAIL FUNGUS - Disclosed is a formulation and method for the treatment of fungal infections of the nail (onychomycosis) utilizing a topical composition comprising zinc pyrithione, a solubilizer for the zinc pyrithione, a film former, and a volatile solvent. The formulation is preferably in the form of a lacquer. The composition containing the metal pyrithione complex is topically applied to the infected nail preferably as a nail polish or lacquer which may be applied with a dropper, swab or the like to the afflicted nail surface. The treatment can be done at least two times a day, with a course of treatment lasting from several weeks to several months or until a cure is effected or a significant reduction of the infection is achieved. | 12-03-2009 |
| 20090306034 | USE OF PICOPLATIN TO TREAT COLORECTAL CANCER - The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment regimens. | 12-10-2009 |
| 20100016271 | ANTI-DANDRUFF HAIR CONDITIONING COMPOSITIONS - A hair conditioning composition comprising a cationic surfactant, triglyceride oil, and an anti dandruff agent. | 01-21-2010 |
| 20100105648 | SOLID PHARMACEUTICAL COMPOSITION COMPRISING (R)-(-)-2-[5-(4-FLUOROPHENYL)-3-PYRIDYLMETHYLAMINOMETHYL]CHROMAN - The invention relates to a solid pharmaceutical preparation containing (R)-(−)-2-[5-(4-fluorophenyl-3-pyridylmethylaminomethyl]chroman as an active substance and at least one sugar alcohol (e.g. mannitol, sorbitol) as a filler. Also disclosed is the production of said solid pharmaceutical preparation, which is provided with an increased shelf life also at elevated temperatures and can be used for the treatment of dyskinesia associated with Parkinson's disease. | 04-29-2010 |
| 20100179117 | SUPEROXIDE DISMUTASE MIMICS FOR THE TREATMENT OF OCULAR DISORDERS AND DISEASES - The use of SOD mimics, particularly Mn(III) salen SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed. | 07-15-2010 |
| 20100204194 | SUPEROXIDE DISMUTASE MIMICS FOR THE TREATMENT OF OCULAR DISORDERS AND DISEASES - The use of SOD mimics particularly pentaazacycle Mn | 08-12-2010 |
| 20100234339 | SILVER(I) COMPOUNDS AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT,PROPHYLAXIS AND PREVENTION OF INFECTIONS - The present invention provides new Ag(I) complexes with derivatives of nicotinic acid, nicotinamide and related pyridine ligands, and pharmaceutical compositions comprising such Ag(I) complexes for use in the treatment, prophylaxis and prevention of infections. The invention further provides a solvent free method for the synthesis of Ag(I) complexes containing substituted pyridines, pyrazines and pyrimidines as ligands. | 09-16-2010 |
| 20100261695 | TREATMENT OF ONYCHOMYCOSIS AND RELATED COMPOSITIONS - The present invention generally relates to the treatment of onychomycosis. More specifically, it relates to combination therapies for the treatment of onychomycosis and related compositions. In a composition aspect, the present invention provides a composition for the treatment of onychomycosis, wherein the composition includes Ciclopirox and at least one other antifungal agent. In a method aspect, the present invention provides a method for treating onychomycosis in a patient suffering from the disease. The method involves topically administering a composition to at least one toe or fingernail of the patient and the composition includes Ciclopirox and at least one other antifungal agent. | 10-14-2010 |
| 20100317640 | ANTIMICROBIAL ZINC PYRITHIONE COMPOSITION AND METHOD - The present invention relates to the field of antimicrobial formulations, and more specifically, to an antimicrobial formulation comprising zinc pyrithione in a stabilized dispersion. | 12-16-2010 |
| 20110015169 | METHODS FOR IN VITRO MATURATION OF OVARIAN FOLLICLES - The invention relates to methods to be used in the maturation of ovarian follicles and oocytes. More specifically, the invention concerns the use of inhibitors of the phosphatase PTEN, such as oxovanadate and peroxovanadate complexes, in methods for in vitro and in vivo maturation of follicles and oocytes. | 01-20-2011 |
| 20110034431 | WATER-SOLUBLE ZINC IONOPHORES, ZINC CHELATORS, AND/OR ZINC COMPLEXES AND USE FOR TREATING CANCER - Disclosed herein are novel zinc ionophores, zinc chelators and/or zinc complexes with enhanced aqueous solubility. Methods of treating cancer using at least one zinc ionophore and/or zinc chelator are also disclosed. Also disclosed herein are compositions and methods for treating cancer with combination therapy using at least one texaphyrin metal complex and at least one zinc ionophore or the respective pharmaceutically acceptable derivatives or salts thereof. | 02-10-2011 |
| 20110071123 | Noninvasive Method for Measuring Histamine From Skin as an Objective Measurement of Itch - A method for measuring of histamine in an epidermis comprising applying an adhesive article to an epithelium of a mammal; allowing for adherence of epithelial cells to the adhesive article; removing the adhesive article from the epithelium of the mammal; preparing the adhesive article using standard laboratory methods for extraction; extracting histamine from the epithelial cells adhered to said adhesive article; measuring histamine from the epithelial cells adhered to said adhesive article; determining the amount of histamine in the epithelial cells as compared to a baseline sample. Further, a method of objectively measuring the perception of itch in mammals and wherein there is a reduction in histamine from a baseline level which is directly proportional to a reduction in an itch perception. | 03-24-2011 |
| 20110098264 | PHARMACEUTICAL COMPOSITION CONTAINING CYCLOMETALATED N-HETEROCYCLIC CARBENE COMPLEXES FOR CANCER TREATMENT - The present disclosure is related to a pharmaceutical composition for treatment of cancer comprising a cyclometalated N-heterocyclic carbene complex. The cyclometalated N-heterocyclic carbene complex contains a gold(III) or a platinum(II) atom. The pharmaceutical composition possesses anti-cancer activity such as the induction of cell death, inhibition of cellular proliferation, inhibition of topoisomerase and/or poisoning of topoisomerase. | 04-28-2011 |
| 20110098265 | METHODS FOR REDUCING CRAVINGS AND IMPULSES ASSOCIATED WITH ADDICTIVE AND COMPULSIVE BEHAVIORS - This document provides methods and materials related to managing weight, supporting appetite control, and controlling cravings associated with smoking reduction or cessation regimens and/or nicotine reduction or cessation regimens. For example, compositions comprising an agent to support acetylcholine and an agent to support one or more biogenic amines, and methods for using such compositions for craving and appetite control are provided. Methods and materials to reduce cravings associated with the reduction or cessation of the use of chemical substances (e.g., drugs of abuse, including opioids, cocaine, methamphetamine, cannabis, alcohol), and to reduce cravings associated with addictive and/or compulsive behaviors (e.g., gambling, sex, and repetitive behaviors) are also provided. | 04-28-2011 |
| 20110105453 | Superoxide Dismutase Mimics For The Treatment Of Optic Nerve And Retinal Damage - Methods for preventing and treating damage to the optic nerve and/or retina by the use of SOD mimics, particularly pentaazacycle Mn | 05-05-2011 |
| 20110136776 | Copper(1)Chloride Complex of Nicotinic Acid and Pharmaceutical Compositions Containing the Same - Copper (I) chloride complex of nicotinic acid and pharmaceutical compositions containing the same. Such pharmaceutical composition are effective for the treatment of myopathy, myasthenia gravis, parkinsonism, Chronic Fatigue Syndrome, Male Infertility and post stroke muscle weakness, muscular dystrophy, skin burns, scars, alopecia, high blood lipids and obesity. | 06-09-2011 |
| 20110152230 | Photoactive Metal Nitrosyls For Blood Pressure Regulation And Cancer Therapy - Disclosed are nitric oxide delivery agents and methods of their use, more specifically to photoactive compounds, which are able to perform targeted delivery of nitric oxide in vitro and in vivo and are useful for medicinal applications including, but not limited, to blood pressure regulation and cancer treatment. | 06-23-2011 |
| 20110195946 | HIGH SOLID DISPERSIONS COMPRISING BIOCIDES - The present invention relates to dispersions comprising a biocide selected from tralopyril, zinc pyrithione or tolylfluanid, or a combination of thereof, a polymeric surfactant, an anti-settling agent and one or more carrier liquids. These dispersions have a solids level up to 80% by weight and provide a zero-dust delivery system when used in antifouling coating formulations. | 08-11-2011 |
| 20110201588 | Post Foaming Gel Composition Comprising An Anti-Irritation Agent - A personal care composition which is preferably a post-foaming gel, said composition comprising an anti-irritation agent; a water dispersible surface active agent, of a carrier comprising water; and optionally a lubricant. | 08-18-2011 |
| 20110294773 | COSMETIC COMPOSITION AND HAIR WASH - To provide a cosmetic composition and a hair wash which are excellent in metal pyrithione salt persistence after washing with a washing liquid containing a surfactant, etc. | 12-01-2011 |
| 20120022037 | AQUEOUS HAIR CLEANSING AGENT - The present invention relates to an aqueous hair cleansing agent which includes the following components (A), (B): (A) sulfate-type anionic surfactant having a specific structure, (B) polyoxyethylene alkyl ether-type nonionic surfactant having a specific structure, and water, wherein ratio of weight represented by (B)/((A)+(B)) is 1% to 25%. | 01-26-2012 |
| 20120077792 | LANTHANIDE METAL COMPLEXES USEFUL IN TREATING CANCER - The present invention relates to a compound of formula (I). Provided is also a method of killing a cell that comprises administering the compound of formula (I). Provided is also a method of treating cancer or diabetes in a mammal that comprises administering the compound of formula I and respective pharmaceutical compositions thereof. | 03-29-2012 |
| 20120115834 | SYNERGISTIC COMBINATION OF FLUMETSULAM OR DICLOSULAM WITH ZINC PYRITHIONE - A synergistic antimicrobial composition containing flumetsulam or diclosulam; and zinc pyrithione. | 05-10-2012 |
| 20120135974 | SYNERGISTIC ANTIMICROBIAL COMPOSITION - A synergistic antimicrobial composition containing 3-iodo-2-propynyl-butylcarbamate and fluometuron. | 05-31-2012 |
| 20120178731 | NASAL, WOUND AND SKIN FORMULATIONS AND METHODS FOR CONTROL OF ANTIBIOTIC-RESISTANT STAPHYLOCOCCI AND OTHER GRAM-POSITIVE BACTERIA - Formulations and methods are disclosed which are effective to kill or control bacteria in the nares including gram-positive bacteria strains of | 07-12-2012 |
| 20120245135 | Gallium Complexes, Pharmaceutical Compositions And Methods Of Use - The present invention provides complexes of gallium with a ligand, methods of making the complexes, methods of using the complexes and pharmaceutical gallium compositions comprising the complexes, in particular those compositions suitable for therapeutic oral administration. | 09-27-2012 |
| 20120309733 | Composition - Hair treatment composition comprising a zinc-based antidandruff agent, a conazole fungicide and a cationic modified guar deposition polymer. | 12-06-2012 |
| 20120329768 | PROCESS OF FORMING CRYSTALS FOR USE IN A PERSONAL CARE COMPOSITION - A method of making a stable detersive surfactant containing personal care composition comprising the steps of emulsifying a stabilizing agent in the presence of anionic surfactant to form an emulsion containing droplets having a particle size of from about 0.1 to about 10 um. These particles are then cooled to form a stabilizing premix at a rate of about 10 to about 1000 C/min to form crystals from the droplets, the crystals having a maximum dimension of about 0.1 to about 3 um. These crystals are then added to a detersive surfactant containing personal care composition to increase stability. | 12-27-2012 |
| 20130040925 | OSMIUM (II) ARENE AZO ANTI-CANCER COMPLEXES - The present invention relates to the use of certain osmium containing complexes such as cytotoxic agents particularly for the treatment of cancer. There is also provided novel osmium containing complexes, as well as pharmaceutical formulations comprising such complexes. | 02-14-2013 |
| 20130045961 | Personal Care Compositions Having Dried Zinc Pyrithione - Personal care compositions including dried zinc pyrithione are provided. Methods are also provided to increase antimicrobial efficacy and enhance deposition of zinc pyrithione | 02-21-2013 |
| 20130079317 | METHODS FOR TREATMENT OF DISEASES - The present disclosure relates to methods of treating a range of diseases or conditions. The methods involve administration of a superoxide dismutase mimetic. | 03-28-2013 |
| 20130109664 | Personal Care Compositions Comprising a Pyrithione and an Iron Chelator | 05-02-2013 |
| 20130150338 | ANTI-DANDRUFF SHAMPOO - The invention relates to an anti-dandruff shampoo comprising:—a) from 0.1 to 5 wt. % of an anti-dandruff zinc salt; b) from 1 to 8 wt. % of an alkyl glycinate and/or alkyl carboxyglycinate; c) from 2 to 16 wt. % of an alkyl sulphate and/or an ethoxylated alkyl sulfate anionic surfactant; and, d) from 1 to 10 wt. % of a fatty acyl isethionate product which product comprises 40 to 80 wt. % fatty acyl isethionate and 15 to 50 wt. % free fatty acid and/or fatty acid salt and to the use of a surfactant system comprising components b) to d) to provide an improvement to the skin stratum corneum barrier. | 06-13-2013 |
| 20130172308 | ANTIMICROBIAL AGENTS - The present invention relates to ruthenium complexes, and in particular di- and multi-nuclear ruthenium complexes which may be used as antimicrobial agents. The invention also relates to pharmaceutical compositions comprising such complexes, and methods for their use in treating or preventing microbial infections. | 07-04-2013 |
| 20130184247 | METHOD FOR PREPARATION OF NICOTINIC ACID COPPER CHLORIDE COMPLEX, AND ITS PHARMACEUTICAL USES - A method for preparation pharmaceutical compounds in large quantities consists of copper (I) halide, preferably the chloride complex of nicotinic acid characterized by elemental analysis, spectroscopy and crystallographic methods, used for treatment of muscular dystrophy, myopathy, myasthenia gravis, parkinsonism, Chronic Fatigue Syndrome, Male Infertility and post stroke muscle weakness. | 07-18-2013 |
| 20130203725 | METHOD TO TREAT SMALL CELL LUNG CANCER - A method for treatment of small cell lung cancer (SCLC) that does not respond to first-line treatment or that progresses following cessation of first-line organoplatinum chemotherapy is provided that includes the administration of picoplatin, optionally in conjunction with a regimen of best supportive care. Multiple doses of picoplatin can be administered. The picoplatin can also treat SCLC that has metastacized to the brain. | 08-08-2013 |
| 20130210793 | PHOTOLABILE CAGED TRANSITION METAL COMPLEXES AND METHODS OF USING THE SAME - The present invention provides compounds of Formula I: | 08-15-2013 |
| 20130225546 | NOVEL SYNTHETIC PROCEDURE AND CANCER TREATMENT WITH CISPLATIN DERIVATIVES - A method of reducing the in vivo viability of cancer cells selected from the group consisting of breast cancer cells, lung cancer cells, prostate cancer cells and melanoma cancer cells has steps of:
| 08-29-2013 |
| 20130225547 | PROTEASOME INHIBITORS AND USES THEREOF - A method of treating a disease in which inhibiting of a proteasome is advantageous is provided. The method comprises administering to the subject a therapeutically effective amount of a compound which binds to a proteasome of a cell, the compound comprising a copper bound to a ligand, the ligand being configured such that upon binding to the proteasome, the copper interacts with cysteine 31 of a Beta2 subunit of the proteasome and further interacts with cysteine 118 of a Beta3 subunit of the proteasome, thereby treating the disease. Additional novel proteasome inhibitors are also provided as well as methods of identifying proteasome inhibitors. | 08-29-2013 |
| 20130252933 | Compositions for Delivering Perfume to the Skin - A cleansing composition comprising at least 5% of a surfactant, at least about 25% water, a cyclodextrin complex comprising a perfume, wherein 80% of the plurality of perfume raw materials comprise a FDV of at least 0.69. | 09-26-2013 |
| 20130289011 | ANTIBACTERIAL DISPERSION - To provide an aqueous antibacterial dispersion which contains a metal pyrithione salt and a cationic polymer and which can maintain a stable dispersed state. An antibacterial dispersion characterized by containing at least one cationic polymer, at least one metal pyrithione salt, and at least one non-anionic surfactant. In an aqueous dispersion of the metal pyrithione salt, the non-anionic surfactant is blended instead of a conventional anionic component, whereby good dispersion stability can be maintained in a cationic polymer blend system. | 10-31-2013 |
| 20130296289 | ANTI-DANDRUFF SHAMPOO - The invention relates to an anti-dandruff shampoo comprising: —a) from 0.1 to 5 wt. % of an anti-dandruff zinc salt; b) from 1 to 8 wt. % of a branched alkyloyi isethionate; c) from 1 to 10 wt. % of a fatty acyl isethionate product which product comprises 40 to 80 wt. % fatty acyl isethionate and 15 to 50 wt. % free fatty acid and/or fatty acid salt; and, d) from 0.5 to 14 wt. % of a co-surfactant; and to the use of the branched alkyloyi isethionate to improve the deposition of an anti-dandruff zinc salt onto the scalp. | 11-07-2013 |
| 20130303503 | Personal Cleansing Compositions Comprising Zinc Pyrithione - The present invention relates to a personal cleansing composition with an antimicrobial effect. The personal cleansing composition is in the form of a bar soap and contains zinc pyrithione and a soap surfactant. When dispersed in an aqueous solution at 1 wt %, the personal cleansing composition of the present invention is characterized by a pH value ranging that is higher than about 9.6 and lower than about 10.3. The present invention also relates to a process for forming an antimicrobial bar soap as described hereinabove. | 11-14-2013 |
| 20140038933 | Composition and Method For Preventing Discoloration of Pyrithione Containing Compositions - The present invention provides a composition containing a pyrithione compound and a pyranone compound and a method of reducing discoloration of compositions containing pyrithione compounds. The composition may be a soap composition. | 02-06-2014 |
| 20140057887 | NOVEL PLATINUM-CARBENE COMPLEXES AND USE THEREOF AS MEDICAMENTS - Disclosed are novel platinum-carbene complexes and use thereof as medicinal products. | 02-27-2014 |
| 20140066419 | HYDROXAMIC ACID DERIVATIVES - The present invention is directed to a method of alleviating, relieving, altering, remedying, ameliorating, improving or affecting a neoplastic disease or an immune disease, the method comprising administering to a subject in need thereof an effective amount of a compound of Formula I, or a pharmaceutically acceptable salt thereof: | 03-06-2014 |
| 20140142080 | NOVEL GOLD(III) COMPLEXES CONTAINING N-HETEROCYCLIC CARBENE LIGAND, SYNTHESIS, AND THEIR APPLICATIONS IN CANCER TREATMENT AND THIOL DETECTION - Provided herein is a method of synthesis of Au(III)-NHC complexes, a pharmaceutical composition comprises thereof. Also provided herein are the methods for the treatment and prevention of cancer/tumor in patients in need thereof by the administration of the Au(III)-NHC complexes. Also provided is method of detecting thiol in a biological system. The Au(III)-NHC complexes possess anticancer activity such as the induction of cell death, inhibition of cellular proliferation, inhibition of thioredoxin reductase activity, and inhibition of tumor growth in vivo. | 05-22-2014 |
| 20140155368 | COMBINATION PHARMACEUTICALS AND METHODS THEREOF USING PROTEINACIOUS CHANNELS AS TREATMENTS FOR MEDICAL CONDITIONS - Methods and combination pharmaceuticals for treating bronchospastic medical conditions by utilizing the electrophysiology of proteinacious channels in lipid membranes of mammalian cells. The combination pharmaceuticals include at least one β-adrenergic receptor agonist, and at least one composition adapted to effect the electrophysiology of Kv7 potassium channels of a lipid membrane of an airway smooth muscle cell. The pharmaceutical may be administered to a living body in a therapeutic amount sufficient to activate the Kv7 potassium channels of an airway smooth muscle cell. | 06-05-2014 |
| 20140243301 | CHLOROBIS COPPER (I) COMPLEX COMPOSITIONS AND METHODS OF MANUFACTURE AND USE - A method of manufacturing an anhydrous copper complex of formula C | 08-28-2014 |
| 20140303135 | Personal Care Compositions Having Dried Zinc Pyrithione-Polymer Aggregates - Personal care composition and methods are included with respect to a dried zinc pyrithione-polymer aggregate. | 10-09-2014 |
| 20140315875 | Personal Care Compositions Containing Zinc Pyrithione and a Metal-Phosphonate Complex - The present invention relates to an antimicrobial bar soap that contains zinc pyrithione and a metal-phosphonate complex and is characterized by enhanced discoloration resistance, extended shelf life and/or increased anti-microbial efficacy. | 10-23-2014 |
| 20140329792 | SYNTHETIC CATALASE/SUPEROXIDE DISMUTASE MIMETICS AND METHODS FOR TREATING VIRAL INFECTIONS - The invention provides for the treatment of disorders related to viral infection, using salen manganese compounds. | 11-06-2014 |
| 20140349985 | PLATINUM COMPOUND HAVING AMINO OR ALKYLAMINO-CONTAINING SUCCINIC ACID DERIVATIVES AS LEAVING GROUP, PREPARTION METHOD THEREOF, AND USE THEREOF - Disclosed are a category of platinum compounds having amino- or alkylamino-containing succinato derivatives as leaving group, or pharmaceutically acceptable salts thereof, preparation method thereof, and medicinal compositions containing the compounds. Also disclosed is a use of the compounds in treating cell proliferative diseases, especially cancers. The platinum compounds of the present invention have high water solubility and small toxic side effect. | 11-27-2014 |
| 20140364407 | MEDICAL OR THERAPEUTIC APPLICATION OF A COMPOSITE MATERIAL OF RUTHENIUM WITH A NITROSYL LIGAND - A medical or therapeutic application of a composite material of ruthenium with a nitrosyl ligand. Application for a medical or therapeutic treatment of a composite material of ruthenium with a nitrosyl ligand irradiated in a spectral range capable of releasing the nitrosyl ligand, i.e., the ultraviolet or visible or near-infrared spectral range. | 12-11-2014 |
| 20150011523 | COMPLEXES OF GERMANIUM WITH AMINO ACIDS AND CARBOXYLIC ACIDS AND METHOD FOR PREPARING SAME - The invention relates to complexes of germanium with amino acids and carboxylic acids of the general formula Ge[OH] | 01-08-2015 |
| 20150065476 | Scalp Care Composition - A scalp care composition comprising from 1% to 99% of a volatile carrier; from 0.05% to 10% of a polymeric rheology modifier and mixtures thereof; from 0.03% to 1% of particulate scalp benefit agent wherein the composition is shear thinning and has (1) a zero shear viscosity value measured at 0.01 Pa of greater than about 1,500 Pa s; (2) a moderate stress viscosity value measured at 1 Pa viscosity of greater than about 1,000 Pa s; and (3) a high shear rate viscosity value measured at 100 1/s of less than about 0.5 Pa s. | 03-05-2015 |
| 20150111863 | Non-Spherical Droplet - Non-spherical liquid droplets comprising a liquid, an internal solid material defining the shape of the droplet, a benefit agent, and methods of making non-spherical liquid droplets. | 04-23-2015 |
| 20150141393 | ENHANCED PRESERVATIVE - A composition having biocidal properties is disclosed. The composition includes a first biocide, optionally a second biocide, and a biocide enhancing agent. The first biocide may comprise an isothiazolin. The second biocide may comprise a pyrithione. The biocide enhancing agent may comprise an amine, an amine salt, an amine oxide, or mixtures thereof. The amine compound may have a carbon chain length of at least six carbon atoms, such as at least eight carbon atoms. | 05-21-2015 |
| 20150296791 | SYNERGISTIC COMBINATION OF A LENACIL COMPOUND AND ZINC PYRITHIONE FOR DRY FILM PROTECTION - A synergistic antimicrobial composition containing lenacil and zinc pyrithione is provided. Also provided is a method of inhibiting the growth of or controlling the growth of microorganisms in a building material by adding such a synergistic antimicrobial composition. Also provided is a coating composition containing such a synergistic antimicrobial composition, and a dry film made from such a coating composition. | 10-22-2015 |
| 20150296792 | SYNERGISTIC COMBINATION OF A ZOXAMIDE COMPOUND AND ZINC PYRITHIONE FOR DRY FILM PROTECTION - A synergistic antimicrobial composition containing zoxamide and zinc pyrithione is provided. Also provided is a method of inhibiting the growth of or controlling the growth of microorganisms in a building material by adding such a synergistic antimicrobial composition. Also provided is a coating composition containing such a synergistic antimicrobial composition, and a dry film made from such a coating composition. | 10-22-2015 |
| 20150306083 | TRIVALENT CHROMIUM COMPOUNDS, COMPOSITIONS AND METHODS OF USE - The present invention provides chromium compounds, specifically chromium dinicocysteinate, which possess the ability to improve insulin sensitization, glucose tolerance, bioavailability, efficacy, and safety, and methods for their use. | 10-29-2015 |
| 20150313864 | Fe(III) Complex Compounds for the Treatment and Prophylaxis of Iron Deficiency Symptoms and Iron Deficiency Anemias - The invention relates to iron(III) complex compounds and pharmaceutical compositions comprising them for the use as medicaments, in particular for the treatment and/or prophylaxis of iron deficiency symptoms and iron deficiency anemias. | 11-05-2015 |
| 20150320874 | METHODS AND COMPOSITIONS FOR THE SUSTAINED RELEASE OF CHROMIUM - Provided herein are compositions for the administration of chromium that include at least two components: a hydrophilic chromium complex and a lipophilic chromium complex, and methods of using the same. Also provided are compositions for the administration of chromium that include a first “fast-acting” chromium complex and a second “slow-acting” chromium complex, wherein the first chromium complex is absorbed more quickly than the slow-acting chromium complex, and methods of using the same. Also provided herein are methods for treating, preventing, and improving conditions associated with cardiometabolic syndrome, by identifying a subject in need of treatment, prevention, or improvement of a condition associated with cardiometabolic syndrome, and providing a therapeutically effective amount of a composition comprising a fast-acting chromium complex and a slow-acting chromium complex, to the individual. | 11-12-2015 |
| 20150335604 | Chromium and Chlorogenic Acid Weight Control Formulations - This invention provides weight loss formulations and methods of use. The formulations include a combination of chlorogenic acids and chromium compounds. The Cr/CGA combination can help reduce blood glucose, while fructose in the formulation provides quick energy and mitigates effects on appetite. The formulations can be introduced into any number of foods and beverages for consumption by dieters as part of their weight loss regimen. | 11-26-2015 |
| 20150344509 | SUBSTITUTED PORPHYRINS - Substituted metalloporphyrin compounds are described, along with pharmaceutical compositions containing the same, and methods of use thereof in protecting cells from oxidant-induced toxicity and pathological conditions such as inflammatory lung disease, neurodegenerative conditions, radiation injury, cancer, diabetes, cardiac conditions and sickle cell disease. Mn(III) porphyrins bearing oxygen atoms within side chains are particularly described. | 12-03-2015 |
| 20160015716 | Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias - The invention relates to iron(III) complex compounds and pharmaceutical compositions comprising them for the use as medicaments, in particular for the treatment and/or prophylaxis of iron deficiency symptoms and iron deficiency anemias. | 01-21-2016 |
| 20160058684 | Bar Soap Compositions Containing Zinc Pyrithione And A Metal-Pyridine Oxide Complex - The present invention relates to a bar soap composition that contains zinc pyrithione (ZPT) and a metal-pyridine oxide complex, preferably a zinc-pyridine oxide complex. The bar soap may be characterized by enhanced discoloration resistance, extended shelf life, and/or increased anti-microbial efficacy. | 03-03-2016 |
| 20160058772 | BISMUTH-THIOLS AS ANTISEPTICS FOR BIOMEDICAL USES, INCLUDING TREATMENT OF BACTERIAL BIOFILMS AND OTHER USES - Compositions and methods, including novel homogeneous microparticulate suspensions, are described for treating natural surfaces that contain bacterial biofilm, including unexpected synergy or enhancing effects between bismuth-thiol (BT) compounds and certain antibiotics, to provide formulations including antiseptic formulations. Previously unpredicted antibacterial properties and anti-biofilm properties of disclosed BT compounds and BT compound-plus-antibiotic combinations are also described, including preferential efficacies of certain such compositions for treating certain gram-positive bacterial infections, and distinct preferential efficacies of certain such compositions for treating certain gram-negative bacterial infections. | 03-03-2016 |
| 20160199384 | Method and Topical Composition for the Treatment of Rosacea and Skin Erythema Using Pyrithione Zinc | 07-14-2016 |
| 20160374914 | ANTI-DANDRUFF COMPOSITIONS AND HAIR CARE FORMULATIONS CONTAINING ZINC PYRITHIONE AND QUATERNARY AMMONIUM SALT - The present invention discloses a stable biocidal composition with enhanced anti-fungal activity at low concentration of active(s) and a process for preparing the same. The composition comprises: zinc pyrithione, C8-C18 quaternary ammonium salt (preferably cetylpyridinium chloride), water miscible glycol/polyol/glycol ether/lactam, organic amine and/or alkanol amine The composition can be formulated into: hair care formulations, antidandruff hair care formulations, water based paints, coatings, adhesives, hard surface cleaners, fabric care compositions, wood products, plastic products and medical products. The biocidal compositions and the resulting formulations are transparent or opaque and are stable at varying pH and humidity conditions. | 12-29-2016 |
| 20160375035 | CHROMIUM HISTIDINATE AND CHROMIUM PICOLINATE COMPLEXES - This present disclosure generally relates to the discovery that chromium histidinate (CrHis) and chromium picolinate (CrPic) can exist as complexes in multiple forms. More particularly, the present disclosure is directed to the surprising discovery that particular forms/isomers (or combinations of forms/isomers) of such chromium complexes have greater activity than others. | 12-29-2016 |
