Class / Patent application number | Description | Number of patent applications / Date published |
514163000 | With carboxylic acid, ester or metal salt thereof | 44 |
20080234235 | Synthesis of Polyanhydrides - The present invention provides a method for forming compounds of Formula | 09-25-2008 |
20080269177 | PESTICIDAL COMPOSITIONS - Pesticidal compositions containing a pesticidally acceptable carrier, and a synergistic blend of plant essential oils as a pesticidally active ingredient and optionally a synergist, and methods for using same, are disclosed. | 10-30-2008 |
20080312196 | Topical wart removal composition - A non-aqueous liquid composition for topical application to warts and other fibroids, papillomas, and other growths for the removal of same is defined by a non-aqueous solution of: (a) at least one keratolytic compound or agent, (b) an adhesive, (c) a dermal regeneration promoter, and (d) a solvent. The composition is applied to the growth or growth site on a daily basis for about at least seven days. The composition can be applied directly to the site or via an impregnated bandage. | 12-18-2008 |
20090036413 | Compositions, uses, and method of making wound care products from naturally occurring food ingredients - Rationally designed wound care products made entirely of naturally occurring food ingredients that can be standardized and made available for the mass market using good manufacturing practice (GMP) guidelines, optionally, a safe food additive can be added. These products: are safe and effective; have an osmotic pressure compatible with optimal healing; are buffered to maintain optimal pH throughout the healing process; provide a protective barrier from further irritation and insult; control bacteria, viruses and fungi found in the skin and mucosa; nourish wounds; control excessive prolonged inflammation and thereby minimize scarring; minimize allergenic and irritation potential; are easy to use or apply; pass the preservative challenge test required for products intended for multiple use; contain fragrant essential oils to take advantage of the benefits provided by aromatherapy; can be individually optimized based on the diet of an individual or group of people. | 02-05-2009 |
20090062240 | Pharmaceutical combinations containing an inhibitor of platelet aggregation and a fibrate - The present invention relates to a novel pharmaceutical combination, containing an inhibitor of platelet aggregation and a fÊbrate, where the inhibitor of platelet aggregation is preferably either aspirin or clopidogreL Such a pharmaceutical combination of an inhibitor of platelet aggregation and a fÊbrate is expected to be useful in the treatment and/or prevention of myocardial infarction (heart attack), cardiac arrest, peripheral vascular disease (including symptomatic carotid artery disease), congestive heart failure, ischemic heart disease, angina pectoris (including unstable angina), sudden cardiac death, unstable angina, as well as cerebrovascular events such as cerebral infarction, cerebral thrombosis, cerebral ischemia and transient ischemic attack, disorders related to bypass operations (angioplasty), fitting of endovascular prostheses and restenosis, and inflammatory disorders, including arthritic conditions such as rheumatoid arthritis and osteoarthritis, as well as asthma or related airway or respiratory inflammatory disorders. | 03-05-2009 |
20090118243 | Compositions and methods for the treatment of ophthalmic conditions - The invention relates to methods of treating ophthalmic conditions comprising administering a compound of formula A, a compound of any one of formulae 1-49, a lipoxin compound, or an oxylipin compound. | 05-07-2009 |
20090192126 | Oral Composition Comprising a Polyunsaturated Fatty Acid and Salicylic Acid for Obtaining an Antiinflammatory Effect in Skin - A composition which is adapted for oral consumption and which is in the form of a substantially homogeneous aqueous emulsion, suspension or dispersion comprising salicylic acid, or a C1 to C6 alkyl ester thereof, and docosahexaenoic acid (DHA) can exhibit an anti-inflammatory effect in skin. | 07-30-2009 |
20090203655 | PROPHYLACTIC DOCOSAHEXAENOIC ACID THERAPY FOR PATIENTS WITH SUBCLINICAL INFLAMMATION - This invention is directed to methods and compositions which impede the development and progression of diseases associated with subclinical inflammation. Subclinical inflammation is commonly associated with atherosclerotic cardiovascular disease, coronary disease or cerebrovascular disease. The methods and compositions of the invention are also particularly suited to providing therapy for subclinical inflammation in diabetic and prediabetic patients. Methods of the invention comprise administration of DHA alone and in combination with antiplatelet drugs. | 08-13-2009 |
20090312292 | Peracetic Acid Composition - The invention relates to anti-microbial compositions useful against a wide range of microorganisms undesirable on a wide variety of materials, including food, food contact and non-food contact surfaces, and surfaces in industrial, recreational, health care, and other institutional environments. More particularly, the anti-microbial compositions comprise peracetic acid in combination with a) citric acid or a salt and b) salicylic acid or a salt in aqueous solution. | 12-17-2009 |
20090318394 | Long Chain Polyunsaturated Fatty Acids and Methods of Making and Using the Same - Disclosed are compositions containing DHA and DPAn-6 and methods of administering and using the same to treat or prevent at least one symptom of inflammation or neurodegeneration or disease states associated with inflammation or neurodegeneration. Also discloses are compositions containing specific dosages and/or ratios of long chain polyunsaturated fatty acids that are particularly effective in reducing or preventing symptoms of inflammation or neurodegeneration. | 12-24-2009 |
20100063009 | Pharmaceutical Combination Comprising 6-Dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1.3-diol and an NSAID - A combination comprising (a) at least one 6-dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3-diol component, and (b) at least one non-steroidal anti-inflammatory drug (NSAID) component; a pharmaceutical composition and a dosage form comprising such as combination, and a method of treating pain and/or ostheoarthritis in a mammal characterized in that components (a) and (b) are administered simultaneously or sequentially to said mammal, in which component (a) may be administered before or after component (b), and in which components (a) or (b) are administered to the mammal either via the same or a different pathway of administration. | 03-11-2010 |
20100204188 | METHOD OF SYNERGISTICALLY ENHANCING THE THERAPEUTIC EFFICACY AND SAFETY OF MEDICATIONS THROUGH A COMBINATION THERAPY - The present invention provides combinations, for treatment of subjects suffering from or at high risk of developing diseases and disorders involving expression of peroxisome proliferator-activated receptors (PPAR). The combinations include abscisic acid and one other bioactive agent, which together provide synergistic effects toward treatment or blocking of development of the disease or disorder. In exemplary embodiments, a combination of abscisic acid and a thiazolidinedione (TZD) is provided for increased insulin sensitivity and improved (i.e., reduced) obesity-induced inflammation. | 08-12-2010 |
20110021468 | TREATMENT OF CARDIOVASCULAR DISEASE WITH SALICYLATES - This invention relates to methods for the treatment of atherosclerotic cardiovascular disease using a non-acetylated forms of salicylate, e.g., salsalate and/or trilisate. | 01-27-2011 |
20110034425 | Method of Treatment for Acute Myelogenous Leukemia - This invention relates to a method of treating acute myelogenous leukemia with TPA along with Dexamethasone and choline magnesium trisalicylate. | 02-10-2011 |
20110082119 | PROPHYLACTIC/AMELIORATING OR THERAPEUTIC AGENT FOR NON-ALCOHOLIC STEATOHEPATITIS - A highly safe and effective prophylactic/ameliorating or therapeutic agent for NACH and the method for using the same are provided. | 04-07-2011 |
20110152222 | USE OF 2,5-DIHYDROXYBENZENE DERIVATIVES FOR THE TREATMENT OF ARTHRITIS AND PAIN - The present invention relates to the use of a compound of Formula (I′″) or pharmaceutically acceptable salt or solvate, isomer or prodrug thereof in the manufacturing of a medicament for the treatment and/or prophylaxis of arthritis and pain. | 06-23-2011 |
20110152223 | THERAPEUTIC AGENT FOR ANCA-RELATED VASCULITIS - Disclosed is an agent for preventing/treating ANCA-related vasculitis and/or preventing the recurrence of ANCA-related vasculitis. Also disclosed is a therapeutic method using the agent. Specifically disclosed is a pharmaceutical composition comprising at least one member selected from the group consisting of eicosapentaenoic acid, a pharmaceutically acceptable salt thereof and an ester thereof as an active ingredient. The pharmaceutical composition is useful for the prevention of recurrence of ANCA-related vasculitis, the treatment of chronic ANCA-related vasculitis, and the prevention and treatment of rapidly progressive glomerulonephritis (RPGN). | 06-23-2011 |
20110178047 | Oxylipins From Long Chain Polyunsaturated Fatty Acids and Methods of Making and Using the Same - Disclosed are novel oxylipins, referred to herein as docosanoids, that are derived from C22 polyunsaturated fatty acids, and method of making and using such oxylipins. Also disclosed is the use of docosapentaenoic acid (C22:5n-6) (DPAn-6), docosapentaenoic acid (C22:5n-3) (DPAn-3), and docosatetraenoic acid (DTAn-6: C22:4n-6) as substrates for the production of novel oxylipins, and to the oxylipins produced thereby. Also disclosed is the use of DPAn-6, DPAn-3, DTAn-6, and/or the oxylipins derived therefrom, and/or novel docosanoids derived from the structures of C22 fatty acids, in therapeutic and nutritional or cosmetic applications, and particularly as anti-inflammatory or anti-neurodegenerative compounds. The invention also relates to novel ways of producing long chain polyunsaturated acid (LCPUFA)-rich oils and compositions that contain enhanced and effective amounts of LCPUFA-derived oxylipins, and particularly, docosanoids. | 07-21-2011 |
20110237555 | USE OF 2,5-DIHYDROXYBENZENE COMPOUNDS AND DERIVATIVES FOR THE TREATMENT OF ROSACEA - The present invention relates to the use of a 2,5-dihydroxybenzene derivative of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the treatment and/or prophylaxis of, inter alia, rosacea. | 09-29-2011 |
20120015912 | USE OF 2,5-DIHYDROXYBENZENE FOR THE TREATMENT OF OCULAR DISEASES - The present invention relates to the use of a compound of Formula (I | 01-19-2012 |
20120046251 | INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE TO INHIBIT OR PREVENT NIACIN-INDUCED FLUSHING - The invention discloses methods of using cis-epoxyeicosantrienoic acids (“EETs”), inhibitors of soluble epoxide hydrolase (“sEH”), or a combination of an EET and an inhibitor of sEH, to reduce or prevent niacin-induced cutaneous vasodilation (“flushing”) in subjects suffering from this undesirable side effect of receiving therapeutic amounts of niacin. | 02-23-2012 |
20120202778 | USE OF AT LEAST ONE OMEGA-3 FATTY ACID AND OF AT LEAST ONE POLYPHENOL FOR THE ENDOGENOUS SYNTHESIS OF EICOSAPENTANOIC ACID AND DOCOSAHEXANOIC ACID - The present invention relates to the use of at least one fatty acid of the omega-3 group, selected from among α-linolenic acid and stearidonic acid, and of at least one polyphenol as an agent for increasing the endogenous synthesis of eicosapentanoic acid and docosahexanoic acid, for preparing a food, health, or pharmaceutical composition to be administered to a human being or to an animal. | 08-09-2012 |
20120302529 | METHOD OF TREATING ACTINIC KERATOSIS AND BASAL CELL CARCINOMA - A method for treating actinic keratosis or basal cell carcinoma. A person's skin is inspected to identify areas that exhibit lesions indicating actinic keratosis or basel cell carcinoma. If such areas are found, a treating composition is applied to the skin in that area. The treating composition may include avobenzone, octocrylene, octyl salicylate, and oxybenzone, and optionally may additionally include SD alcohol 40, C | 11-29-2012 |
20130210776 | COMPOSITION FOR THE TREATMENT OF SUPERFICIAL LESIONS - The invention relates to a composition for the treatment of superficial lesions, in particular skin lesions, mucous membrane lesions and/or nail lesions, an applicator comprising such a composition and the use of such a composition. The composition comprises an effective amount of trichloroacetic acid, at least one thickener, and at a physiologically acceptable solvent. And is effective against a plethora of superficial lesions selected from the group consisting of viral warts, verrucae, water warts (molluscum contagiosum), corns and calluses, and skin hyperpigmentation: age spots, solar lentigo, senial lentigo, acne, keratosis pilaris, actinic keratosis, mouth ulcers (canker sores), cold sores, ingrown toenails, onychomycosis, eyelid xanthelasma. | 08-15-2013 |
20130210777 | Amelioration of the Appearance of Bruises - The present invention is directed to compositions and processes for their use that ameliorate the appearance of bruises, making them less cosmetically unappealing. The composition functions by acting both as a humectant and occlusive agent attracting water, returning the skin surface to a smooth state and holding water in place. The re-establishment of a homeostatic state in the skin results in a rapid dissipation of the negative cosmetic effects of the bruise on the skin. | 08-15-2013 |
20130237505 | TOPICAL COMPOSITIONS FOR TREATMENT OF SKIN CONDITIONS - The invention provides a topical formulation adapted for treatment of a skin condition comprising (i) at least one retinoid; and (ii) salicylic acid or an ester, amide, salt, or solvate thereof. The invention also includes a kit for treatment of skin conditions comprising a retinoid and salicylic acid, as well as a method of treating skin conditions utilizing the inventive formulation and kit. | 09-12-2013 |
20130261092 | METHOD OF SYNERGISTICALLY ENHANCING THE THERAPEUTIC EFFICACY AND SAFETY OF MEDICATION THROUGH A COMBINATION THERAPY - The present invention provides combinations, for treatment of subjects suffering from or at high risk of developing diseases and disorders involving expression of peroxisome proliferator-activated receptors (PPAR). The combinations include abscisic acid and one other bioactive agent, which together provide synergistic effects toward treatment or blocking of development of the disease or disorder. In exemplary embodiments, a combination of abscisic acid and a thiazolidinedione (TZD) is provided for increased insulin sensitivity and improved (i.e., reduced) obesity-induced inflammation. | 10-03-2013 |
20130281411 | COMPOSITIONS FOR TREATING INFLAMMATORY DERMATOLOGICAL DISEASES AND CONDITIONS AND METHODS OF USE THEREOF - Compositions are disclosed that contain an effective inflammatory-dermatological disease-treating or condition-treating active agent and a pharmaceutically-acceptable carrier or vehicle. Methods of using the compositions to treat a subject's skin are also disclosed. | 10-24-2013 |
20130289006 | COMPOSITIONS FOR TREATING HYPERPIGMENTATION AND METHODS OF USE THEREOF - Compositions are disclosed that contain an effective hyperpigmentation-treating active agent and a pharmaceutically-acceptable carrier or vehicle. Methods of using the compositions to treat hyperpigmentation are also disclosed. | 10-31-2013 |
20130324502 | NOVEL FORMULATIONS FOR DERMAL, TRANSDERMAL AND MUCOSAL USE 1 - A dermal, transdermal and/or mucosal formulation for topical application on skin, comprising an active pharmaceutical ingredient and a pharmaceutically acceptable solvent, and an anti-solvent; wherein the active pharmaceutical ingredient is soluble in the solvent in the absence of the anti-solvent, and wherein the active pharmaceutical ingredient is substantially in the solid state in the presence of the anti-solvent. A method for increasing the stability of an active pharmaceutical ingredient. | 12-05-2013 |
20130331362 | Ophthalmic Solution For Absorbing Ultraviolet Radiation and Method For Absorbing Ultraviolet Radiation - An ophthalmic solution is provided. The ophthalmic solution includes an ultraviolet-A absorber and an ultraviolet-B absorber. The ophthalmic solution has a viscosity of between about 1 and 100 cps. The ophthalmic solution can be used to absorb ultraviolet radiation in the eye. | 12-12-2013 |
20140005151 | REDUCTION IN COMPLEMENT ACTIVATION AND INFLAMMATION DURING TISSUE INJURY BY CAROTENOIDS, CAROTENOID ANALOGS, OR DERIVATIVES THEREOF | 01-02-2014 |
20140018330 | Use Of 2,5-Dihydroxybenzene Compounds And Derivatives For The Treatment Of Rosacea - The present invention relates to the use of a 2,5-dihydroxybenzene derivative of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the treatment and/or prophylaxis of, inter alia, rosacea. | 01-16-2014 |
20140066414 | TOPICAL COMPOSITIONS FOR TREATMENT OF SKIN CONDITIONS - The invention provides a topical formulation adapted for treatment of a skin condition comprising (i) at least one retinoid; and (ii) salicylic acid or an ester, amide, salt, or solvate thereof. The invention also includes a kit for treatment of skin conditions comprising a retinoid and salicylic acid, as well as a method of treating skin conditions utilizing the inventive formulation and kit. | 03-06-2014 |
20140100202 | PROCESS FOR THE PREPARATION OF A METAL COMPLEX IN AN OILY ORGANIC MATRIX - A process is described for the preparation of a composition comprising a metal complex in an oily organic matrix, the latter being at the same time able to promote the formation of the complex. Said process also envisages that the complex, once formed, is not separated from said oily organic matrix, but the resulting composition is used as such, as having observed that the performances of the complex present therein is thus improved. | 04-10-2014 |
20140179645 | ANTIMICROBIAL COMPOSITIONS - Described herein are antimicrobial compositions, methods of making thereof, a kit comprising said compositions, and methods for removing microorganisms from surfaces by using said compositions. In one aspect, the antimicrobial composition is a kit composed of a first composition that comprises a dissolved metal salt and a second composition that comprises a ligand, wherein the ligand comprises (i) a residue of antibacterial agent and (ii) a residue of an antifungal agent, wherein the antibacterial agent and/or antifungal agent comprises at least one aryl group. These compositions can further comprise (a) surfactants and/or emulsifiers, (b) thickeners, and (c) solvents or carriers such as water, propylene glycol, and glycerin. In some aspects, these compositions can also comprise fragrances, humectants, emollients, essential oils, plant extracts, and other natural products. Optional additives that are known in the art may also be included. | 06-26-2014 |
20140206654 | USE OF 2,5-DIHYDROXYBENZENE COMPOUNDS AND DERIVATIVES FOR THE TREATMENT OF HEMATOLOGICAL DYSCRASIAS AND CANCER OF AN ORGAN - The present invention refers to the use of a compound of Formula (I′) or pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the treatment and/or prophylaxis of hematological dyscrasias, including myelodysplastic syndromes (MDSs) and for improving the efficacy of chemotherapy, radiation therapy and/or cancer immunotherapy. In addition, it relates to the use of a compound of formula (I″) for the treatment and/or prophylaxis of cancer of an organ. | 07-24-2014 |
20140249115 | METHOD OF ADMINISTRATION OF GAMMA HYDROXYBUTYRATE WITH MONOCARBOXYLATE TRANSPORTERS - One embodiment of the present invention is to improve the safety and efficacy of the administration of GHB or a salt thereof to a patient. It has been discovered that the concomitant administration of an MCT inhibitor, such as diclofenac, valproate, or ibuprofen, will affect GHB administration. For example, it has been discovered that diclofenac lowers the effect of GHB in the body, thereby potentially causing an unsafe condition. Furthermore, it has been discovered that valproate increases the effect of GHB on the body, thereby potentially causing an unsafe condition. | 09-04-2014 |
20150072960 | Compositions And Methods Of Use Of Phorbol Esters In The Treatment Of Neoplasms - Methods and compositions containing a phorbol ester or a derivative of a phorbol ester are provided for the treatment of chronic and acute conditions. Such conditions may be caused by disease, be symptoms, treatments, or sequelae of disease. The phorbol esters described are particularly useful in the treatment of neoplastic diseases and/or managing the side effects of chemotherapeutic and radiotherapeutic treatments of neoplastic diseases. | 03-12-2015 |
20150094286 | MULTIFUNCTIONAL TOPICAL FORMULATION FOR THE TREATMENT OF ACNE VULGARIS AND OTHER SKIN CONDITIONS - A two-part aqueous composition for treating skin ailments, such as acne vulgaris, includes an acidic part having salicylic acid and an α-hydroxy acid, and an alkaline part having an alkaline nitrite salt. The α-hydroxy acid is preferably glycolic acid, lactic acid, malic acid, mandelic acid or a combination thereof. The alkaline nitrite salt is preferably sodium nitrite. The acidic part and the alkaline part are an acidic aqueous solution and an alkaline aqueous solution, respectively, which may either be mixed with one another then applied to an affected portion of a patient's skin or, alternatively, may be sequentially applied to the affected portion of the patient's skin, preferably within 15 minutes of one another. | 04-02-2015 |
20150148320 | COSMETIC USE OF SALICYLIC ACID DERIVATIVES - Cosmetic compositions comprising salicylic acid derivatives and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The salicylic acid derivatives are believed to have modulatory activity against one or more biochemical pathways implicated in the appearance of human skin. | 05-28-2015 |
20150320679 | GEL COMPOSITIONS - Novel aqueous topical gel compositions comprising ingenol-3-angelate. | 11-12-2015 |
20150374648 | Compositions And Methods Of Use Of Phorbol Esters In The Treatment Of Neoplasms - Methods and compositions containing a phorbol ester or a derivative of a phorbol ester are provided for the treatment of chronic and acute conditions. Such conditions may be caused by disease, be symptoms, treatments, or sequelae of disease. The phorbol esters described are particularly useful in the treatment of neoplastic diseases and/or managing the side effects of chemotherapeutic and radiotherapeutic treatments of neoplastic diseases. | 12-31-2015 |
20160073628 | High Osmolarity Antimicrobial Composition Containing One or More Organic Solvents - A composition that can solvate biofilms and disrupt bacterial cell walls acts to both kill the bacteria by cell lysis and remove the biofilm. This solvent-containing composition is effective against a broad spectrum of microbes and can be used on a variety of surfaces, both living and inanimate. The polarity of the solvent component of the composition lower than that of pure water so that the composition exhibits increased efficacy in solvating the macromolecular matrix of a biofilm and in penetrating bacterial cell walls. | 03-17-2016 |