| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 514153000 | With stabilizer or preservative | 10 |
| 20110118216 | Tigecycline Compositions and Methods of Preparation - The present invention relates to novel tigecycline compositions with improved stability in both solid and solution states and processes for making these compositions. These compositions comprise tigecycline, a suitable carbohydrate, and an acid or buffer. | 05-19-2011 |
| 20120028929 | TETRACYCLINE STABILIZING FORMULATIONS - An aqueous solution comprising a chelating agent at a concentration of about 0.1-0.5%, and an antioxidant agent at a concentration of about 0.1-0.5%, wherein the pH of the solution is between about 4.5 and about 7.5 is disclosed. The aqueous solution may comprise a tetracycline composition wherein the tetracycline is formulated in the aqueous solution. A method for reducing the rate and/or overall extent of degradation of a tetracycline in aqueous solution, comprising admixing in a tetracycline containing solution a chelating agent at a concentration of about 0.1-0.5% and an antioxidant at a concentration of about 0.1-0.5% and, as necessary, adjusting the pH of the solution so that it is between about 4.5 and about 7.5 is also disclosed. Tetracycline compositions of the invention may be used to treat inflammatory and/or tissue degeneration conditions. | 02-02-2012 |
| 20120190653 | THERAPEUTIC EYE DROP COMPRISING DOXYCYCLINE AND A STABILIZER - The present invention provides stable aqueous doxycycline aqueous solutions suitable for pharmaceutical, especially ophthalmic, use. The doxycycline aqueous solutions have a pH ranging from 4.5-8, and contain an antioxidant and a stabilizer such as caffeine, creatine or mixtures thereof. The solutions have improved lifetimes and can be used topically. | 07-26-2012 |
| 20130040918 | TETRACYCLINE COMPOSITIONS - The present invention relates to compositions, pharmaceutical compositions, and methods for preparing the same, comprising a tetracycline with improved stability and solubility. Some embodiments include a tetracycline with an excess of a divalent or trivalent cation. | 02-14-2013 |
| 20140194393 | TETRACYCLINE COMPOSITIONS - The present invention relates to compositions, pharmaceutical compositions, and methods for preparing the same, comprising a tetracycline with improved stability and solubility. Some embodiments include a tetracycline with an excess of a divalent or trivalent cation. | 07-10-2014 |
| 20150057254 | ONCE DAILY FORMULATIONS OF TETRACYCLINES - Disclosed are once-daily formulations containing tetracyclines, especially doxycycline. Such formulations are useful, for instance, for the treatment of collagenase destructive enzyme-dependent diseases, such as periodontal disease and acne, and acute and chronic inflammatory disease states, such as rosacea and arthritis. | 02-26-2015 |
| 20150141379 | TIGECYCLINE COMPOSITIONS AND METHODS OF PREPARATION - The present invention relates to novel tigecycline compositions with improved stability in both solid and solution states and processes for making these compositions. These compositions comprise tigecycline, a suitable carbohydrate, and an acid or buffer. | 05-21-2015 |
| 20160058865 | STABLE TIGECYCLINE COMPOSITION - The present invention relates to a stable pharmaceutical composition of Tigecycline and process for the preparation of the same. The composition comprises Tigecycline and maltose wherein the pH of the bulk solution or solution after reconstitution is in between 3-6. | 03-03-2016 |
| 20160143925 | STABLE PHARMACEUTICAL COMPOSITIONS - The present invention relates to a stable pharmaceutical composition comprising tigecycline and arginine, to a process for the manufacture of said pharmaceutical composition as well as to its use in the treatment of bacterial infections. | 05-26-2016 |
| 20160144036 | TIGECYCLINE COMPOSITIONS AND METHODS OF PREPARATION - The present invention relates to novel tigecycline compositions with improved stability in both solid and solution states and processes for making these compositions. These compositions comprise tigecycline, a suitable carbohydrate, and an acid or buffer. | 05-26-2016 |
