| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 436131000 | Hydroxyl containing | 40 |
| 20100022019 | METHOD OF MONITORING ADSORBENT BED BREAKTHROUGH IN A PROCESS FOR PRODUCING ALKYL ESTERS FROM VEGETABLE OR ANIMAL OIL AND FROM AN ALIPHATIC MONOALCOHOL - A method of monitoring breakthrough of an adsorbent bed consisting for example of ion-exchange resins, used during a stage of purification of an ester stream containing glycerin, obtained for example in a vegetable or animal oil and aliphatic monoalcohol transesterification process, permits the instantaneous detection of the presence of glycerol (glycerin) in the ester stream by arranging a turbidimeter at the adsorbent bed outlet. | 01-28-2010 |
| 20100075432 | SENSOR - This invention relates to a sensor and in particular to a sensor for the detection of biologically important species. Specifically, the invention provides a sensor for detecting an analyte in a sample. The sensor comprises a transducer and a receptor layer in electrical communication with the transducer, wherein the receptor layer comprises a receptor material and a dispersed electrically conductive material | 03-25-2010 |
| 20100093103 | DETECTION OF BLOOD PLASMA SCHIZADRIN B OF DISSIPATING BLOOD STASIS BOTANICAL - A detection method of blood plasma schizadrin B of dissipating blood stasis botanical is disclosed. The method includes: (1) extracting schizadrin B from plasma of mammalian administered dissipating blood stasis botanical by ethyl acetate with the volume ratio 1:4, whirling 3-5 mins, centrifugating at 9600 rpm for 10 mins, drying and enriching the upper layer at 25-30° C., and redissolving with mobile phase; (2) UPLC/MS measuring: UPLC condition: chromatographic column: Acquity UPLC BEH C | 04-15-2010 |
| 20100173421 | SENSOR - This invention relates to a sensor and in particular to a sensor for the detection of biologically important species. Specifically, the invention provides a method for detecting an analyte in the presence of at least one interferent in a sample. The method comprises the steps of providing a sensor having a transducer and a receptor layer in communication with the transducer, in which the receptor layer comprises a material for absorbing the analyte; exposing the receptor layer to the sample; treating the receptor layer to remove selectively the at least one interferent; and measuring the signal from the transducer. The treatment step is performed by applying a change in potential, a change in pH or a change in temperature to the receptor layer, by washing the receptor layer, by irradiating the receptor layer, or a combination thereof. | 07-08-2010 |
| 20100178707 | VITAMIN D DEFICIENCIES - Methods for determining the amount of vitamin D compounds in a sample are provided. The methods can employ LC-MS/MS techniques and optionally the use of deuterated internal standards. Methods for diagnosing vitamin D deficiencies are also provided. | 07-15-2010 |
| 20100227412 | Simultaneous Detection of Estrogen and Non Estrogen Steroids - Methods for determining the amounts of estrogen and non-estrogen steroids in a sample are provided. The methods employ the selective derivatization of estrogen steroids present in a sample and detection of the molecular ions and fragments of the derivatized estrogens and non-estrogen steroids in the sample. The methods provided herein enable the simultaneous quantification of estrogen and non-estrogen steroids in a sample. | 09-09-2010 |
| 20100248381 | Methods for Detecting Urushiol-Bearing Plants - The present invention provides methods for detecting urushiol-bearing plants such as poison ivy, poison oak, and poison sumac. Accordingly, one aspect of the invention is a method of detecting a urushiol-bearing plant, the method comprising: dispensing a urushiol marking composition on a surface of the urushiol-bearing plant; then detecting a visual change on the urushiol-bearing plant caused by the reaction of the urushiol marking composition with the urushiol borne by the urushiol-bearing plant. | 09-30-2010 |
| 20100285603 | MEASUREMENT OF VITAMIN D - The present invention relates to a method of measuring a vitamin D metabolite in a sample, the method comprising the steps of (a) treating said sample with a vitamin D metabolite releasing reagent under conditions appropriate to release a vitamin D metabolite from vitamin D-binding protein and not to cause protein precipitation, (b) subjecting the treated sample obtained in step (a) to a chromatographic separation, and (c) measuring a vitamin D metabolite during or after said chromatographic separation. The present invention also relates to methods for determining the vitamin D status of a subject, for use in the diagnosis of disease, and to agents and kits for use in performing the methods of the invention. | 11-11-2010 |
| 20110183429 | QUANTITATIVE ANALYSIS OF VITAMIN D3, VITAMIN D2, AND METABOLITES THEREOF - Quantification of vitamin D2, vitamin D3, and the monohydroxy and diihydroxy metabolites of vitamin D2 and vitamin D3, can comprise labeling analytes with mass spectrometry (MS) tagging reagents and performing LC-MSMS analysis of the labeled analytes. The labeled analytes can include a labeled standard and can have distinct retention times on a reversed phase column, as well as distinct masses. Under high energy collisions, reporter groups can be generated. The intensity or the peak area detected for each reporter group can be used for quantitation. In some embodiments, a one-step tagging reagent is used that is a dienophile-containing, labeled Diels Alder reagent. | 07-28-2011 |
| 20110195513 | Methods And Kits For The Determination Of The Presence And Quantity of Vitamin D Analogs In Samples - Embodiments of the present invention are directed to methods and kits for determining the presence or absence, and the amount if present, of vitamin D analogs in samples. One embodiment of the present method for detecting the presence or absence of vitamin D analogs in a sample comprises the steps of adding an effective amount of a multiple charge cationic agent to the sample to form a cationic treated sample. The effective amount of a multiple charge cationic agent enhances the signal from vitamin D analogs upon analysis by mass spectroscopy. | 08-11-2011 |
| 20110212534 | METHODS FOR DETERMINING LEVELS OF 1,25 DIHYDROXY VITAMIN D2 AND D3 - Methods for determining the amount of DHVD2 and/or DHVD3 in a sample are provided. The methods can employ LC-MS/MS techniques coupled with sample affinity purification and derivatization steps. Methods for diagnosing vitamin D deficiencies are also provided. | 09-01-2011 |
| 20120115240 | Treatment of ruminant exhalations - Methane gas in a ruminant exhalation may be oxidized to reduce the amount of methane gas output by the ruminant. | 05-10-2012 |
| 20120190121 | METHODS FOR DETECTING DIHYDROXYVITAMIN D METABOLITES BY MASS SPECTROMETRY - Provided are methods of detecting the presence or amount of a dihydroxyvitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a dihydorxyvitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. In certain preferred embodiments the methods include immunopurifying the dihydroxyvitamin D metabolites prior to mass spectrometry. Also provided are methods to detect the presence or amount of two or more dihydroxyvitamin D metabolites in a single assay. | 07-26-2012 |
| 20120231549 | SENSING HYDROXYL RADICALS IN OZONE WASHING SYSTEMS - Implementations and techniques for sensing hydroxyl radicals in ozone washing systems are generally disclosed. | 09-13-2012 |
| 20120244627 | Methods for Quantifying Vitamin D Metabolites by Mass Spectrometry - Provided are methods of detecting the presence or amount of a dihydroxyvitamin D metabolite in a sample using mass spectrometry. The methods generally comprise associating an amine with a dihydroxyvitamin D metabolite in a sample, ionizing the adduct, and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. | 09-27-2012 |
| 20130040398 | VITAMIN D DEFICIENCIES - Methods for determining the amount of vitamin D compounds in a sample are provided. The methods can employ LC-MS/MS techniques and optionally the use of deuterated internal standards. Methods for diagnosing vitamin D deficiencies are also provided. | 02-14-2013 |
| 20130078729 | RELEASE REAGENT FOR VITAMIN D COMPOUNDS - A reagent composition for releasing vitamin D compounds bound to vitamin D-binding protein, an in vitro method for the detection of a vitamin D compound in which the vitamin D compound is released from vitamin D-binding protein by the use of this reagent composition and the reagent mixture obtained in this manner. The use of the disclosed reagent composition to release vitamin D compounds as well as a kit for detecting a vitamin D compound which contains the reagent composition for releasing vitamin D compounds in addition to common detecting reagents. | 03-28-2013 |
| 20130143329 | METHODS FOR DETECTING DIHYDROXYVITAMIN D METABOLITES BY MASS SPECTROMETRY - Provided are methods of detecting the presence or amount of a dihydroxyvitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a dihydorxyvitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. In certain preferred embodiments the methods include immunopurifying the dihydroxyvitamin D metabolites prior to mass spectrometry. Also provided are methods to detect the presence or amount of two or more dihydroxyvitamin D metabolites in a single assay. | 06-06-2013 |
| 20130236979 | METHODS FOR DETECTING VITAMIN D METABOLITES BY MASS SPECTROMETRY - Provided are methods of detecting the presence or amount of a vitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a vitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. Also provided are methods to detect the presence or amount of two or more vitamin D metabolites in a single assay. | 09-12-2013 |
| 20130244335 | VITAMIN D DEFICIENCIES - Methods for determining the amount of vitamin D compounds in a sample are provided. The methods can employ LC-MS/MS techniques and optionally the use of deuterated internal standards. Methods for diagnosing vitamin D deficiencies are also provided. | 09-19-2013 |
| 20130252342 | Detection And Quantification Of Vitamin D Metabolites Using An Alkylamine To Form Stable Adducts For Mass Spectrometric Analysis - The invention describes a method of determining the amount of an analyte in a sample wherein the analyte comprises one or more vitamin D metabolites; comprising the steps of; contacting the analyte with an alkylamine to form an alkylamine adduct; subjecting the adduct to a MS technique to determine the amount of the adduct; and calculating the amount of the analyte equivalent to the amount of the adduct. | 09-26-2013 |
| 20130316464 | ANALYTE EXTRACTION APPARATUS AND METHOD - Disclosed is an apparatus for automatically extracting i2,6-diisopropylphenol (Propofol), from a complex sample matrix comprising cellular material, e.g. blood, the apparatus comprising a sample reception stage having on output for providing a defined quantity of the complex sample matrix; a mixing stage having a first input in fluidic connection with the output of the sample reception stage, a second input for receiving a lysing agent and an output for providing a mixture of the defined quantity of the complex sample matrix and the lysing agent; a delay stage having an input in fluidic connection with the output of the mixing stage and an output for providing the delayed mixture of the defined quantity of the complex sample matrix and the lysing agent; a filtering stage comprising a sorbent material for mechanically lysing the cellular material, said sorbent material having an affinity for binding Propofol, said filtering stage having an input in fluidic connection with the output of the delay stage; and a controller for controlling the flow rate of the mixture of the defined quantity of the complex sample matrix and the lysing agent through said delay stage. A method for such extraction is also disclosed. | 11-28-2013 |
| 20140024130 | CHEMICAL BREATH TESTING DEVICE FOR DETECTING ALCOHOL INCLUDING A TESTING TUBE AND AN INFLATABLE BAG - The invention relates to a chemical breath testing device including a transparent testing tube which cooperates with an outlet piece incorporating a valve and fitted to an inflatable bag. The testing tube is provided with a member for pushing the valve which is formed by the bottom of a cap. The outer sidewall of the cap is resiliently deformable and serves to form an interlocking connection between the testing tube and the outlet piece. The cap is mounted in a mobile manner at the end of the testing tube and carries a cutting blade for cutting a seal closing off the outlet of the testing tube, of which the rim forms a counter-blade. | 01-23-2014 |
| 20140030813 | SYSTEM AND METHOD FOR MEASURING HYDRO CARBONATE CONTENT IN MINERALS - System for measuring the hydro carbonate content in minerals, particularly pyrobituminous shale minerals, while they pass through the transport or production system, in such a way as to permit the prior adjustment of the processing conditions of said minerals. The system consists of a set of equipment for the measurement of water content, material density and hydrogen content in the mineral, said equipment being combined in such a way as to create a specific time delay between the measurements, in order for the collected data to be micro processed and the processing conditions to be adjusted in real time, based on the calculated hydro carbonate content. | 01-30-2014 |
| 20140051176 | VITAMIN D METABOLITE DETERMINATION UTILIZING MASS SPECTROMETRY FOLLOWING DERIVATIZATION - The invention relates to the detection of vitamin D metabolites. In a particular aspect, the invention relates to methods for detecting derivatized vitamin D metabolites by mass spectrometry. | 02-20-2014 |
| 20140065717 | METHOD AND APPARATUS FOR MEASURING CONCENTRATION OF ADVANCED-OXIDATION ACTIVE SPECIES - A method for measuring the concentration of advanced-oxidation active species includes a step of measuring the absorption characteristics of a wavelength region including the wavelength of 195 to 205 nm of a sample and a step of determining the concentration of the advanced-oxidation active species from the aforementioned measured absorption characteristics on the basis of the absorption coefficient of the advanced-oxidation active species in the wavelength region including the wavelength of 195 to 205 nm. The method and the apparatus can measure the concentration of the advanced-oxidation active species directly in line without the need for adding an additive. | 03-06-2014 |
| 20140127825 | QUANTITATIVE ANALYSIS OF VITAMIN D3, VITAMIN D2, AND METABOLITES THEREOF - Quantification of vitamin D2, vitamin D3, and the monohydroxy and diihydroxy metabolites of vitamin D2 and vitamin D3, can comprise labeling analytes with mass spectrometry (MS) tagging reagents and performing LC-MSMS analysis of the labeled analytes. The labeled analytes can include a labeled standard and can have distinct retention times on a reversed phase column, as well as distinct masses. Under high energy collisions, reporter groups can be generated. The intensity or the peak area detected for each reporter group can be used for quantitation. In some embodiments, a one-step tagging reagent is used that is a dienophile-containing, labeled m Diels Alder reagent. | 05-08-2014 |
| 20140162371 | METHODS FOR DETECTING VITAMIN D METABOLITES BY MASS SPECTROMETRY - Provided are methods of detecting the presence or amount of a vitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a vitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. Also provided are methods to detect the presence or amount of two or more vitamin D metabolites in a single assay. | 06-12-2014 |
| 20140242712 | FLUORESCENCE DETECTION OF POISON OAK OIL - The invention herein disclosed provides for compositions, methods for synthesizing said compositions, and methods for using said compositions, wherein the compositions and methods may be used to bind to and/or deactivate a poison oak oil, such as urushiol. The compositions and methods can be used to treat and/or reduce an inflammatory reaction and/or hypersensitivity to natural compounds found in poison oak, poison ivy, poison sumac, mango, lac tree, and cashew nut. | 08-28-2014 |
| 20140248707 | RELEASE REAGENT FOR VITAMIN D COMPOUNDS - A reagent composition for releasing vitamin D compounds bound to vitamin D-binding protein and an in vitro method for the detection of a vitamin D compound in which the vitamin D compound is released from vitamin D-binding protein by the use of this reagent composition as well as the reagent mixture obtained in this manner. Also disclosed is the use of the reagent compositions to release vitamin D compounds as well as a kit for detecting a vitamin D compound. | 09-04-2014 |
| 20140273260 | Method for Determining Derivatized Analytes in A Separated Biological Fluid - The present invention comprises methods for determining the presence, amount, or concentration of analytes of interest including Vitamin D and other secosteroids from biological samples, through derivatization, with improved speed and ease of analysis and improved sensitivity to mass spectrometry. In a preferred embodiment, the present invention comprises methods for determining the presence, amount, or concentration of analytes of interest, including Vitamin D and other secosteroids from whole human blood, through derivatization, and using a plasma collection device to facilitate collection, separation, and preparation of the sample for derivatization and analysis. | 09-18-2014 |
| 20150024506 | RELEASE REAGENT FOR VITAMIN D COMPOUNDS - A reagent composition for releasing vitamin D compounds bound to vitamin D-binding protein, an in vitro method for the detection of a vitamin D compound in which the vitamin D compound is released from vitamin D-binding protein by the use of this reagent composition and the reagent mixture obtained in this manner. The use of the disclosed reagent composition to release vitamin D compounds as well as a kit for detecting a vitamin D compound which contains the reagent composition for releasing vitamin D compounds in addition to common detecting reagents. | 01-22-2015 |
| 20150309055 | METHDOS FOR DETECTING ESTRADIOL BY MASS SPECTROMETRY - Provided are methods for determining the amount of estradiol in a sample using mass spectrometry. The methods generally involve ionizing estradiol in a sample and detecting and quantifying the amount of the ion to determine the amount of estradiol in the sample. | 10-29-2015 |
| 20150323520 | DIAGNOSIS OF KIDNEY TRANSPLANT ACUTE REJECTION - A method for identifying a kidney condition of a patient includes receiving a urine sample from a patient. The patient provides the urine sample a predetermined amount of time after having been administered a dose of a sugar alcohol. The method also includes determining whether the sugar alcohol is present in the urine sample. The method also includes identifying a kidney condition of the patient, if the sugar alcohol is present in the urine sample. | 11-12-2015 |
| 20150355202 | VITAMIN D MEASUREMENT METHOD AND MEASUREMENT KIT - The present invention provides a method of measuring a vitamin D. | 12-10-2015 |
| 20160139157 | METHODS FOR DETECTING VITAMIN D METABOLITES BY MASS SPECTROMETRY - Provided are methods of detecting the presence or amount of a vitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a vitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. Also provided are methods to detect the presence or amount of two or more vitamin D metabolites in a single assay. | 05-19-2016 |
| 20160202220 | LIQUID PHASE PHENOL ANALYSIS | 07-14-2016 |
| 20160202221 | Material for detecting phenol derivatives and applications thereof | 07-14-2016 |
| 436132000 | Ethanol | 2 |
| 20090087920 | Method and apparatus for assessing blood-concentration of a volatile constituent - A method and apparatus for of assessing the blood concentration level in a human or animal subject, of a volatile blood constituent (preferably alcohol) is disclosed. The method comprises steps of positioning a sensor ( | 04-02-2009 |
| 20160041147 | COMPOSITION FOR THE DETECTION OF ALCOHOL VAPORS IN AN AIR SAMPLE - The present invention relates to a silica gel-based composition capable of changing color when placed in contact with alcohol vapors. Said composition is particularly useful for preparing devices for the detection of alcohol, for example devices for carrying out an alcohol test on samples of air exhaled by individuals when subjected to checks by the police or competent authorities. | 02-11-2016 |
