| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 436018000 | Preservative, buffer, anticoagulant or diluent | 8 |
| 20080261312 | Methods for matrix cleanup and analysis of drugs and metabolites in biological matrices - The invention is directed to the use of weak anion exchange (WAX) materials for trapping of negative and zwitterionic interferences from biological matrices, and then reduction of the biological matrix effect in the quantitative analysis process of basic and neutral compounds present in the matrix. The sample preparation process includes adding the WAX cleanup step before or after or during the conventional extraction procedures like liquid-liquid extraction, protein precipitation, solid phase extraction and others. Such a step greatly enhances the selectivity of the extraction process via the removal of the majority of the contaminants and reduces the matrix effect in the quantitative analysis. In addition, the WAX-enhanced extraction is very simple, versatile, rug and easy to be operated. | 10-23-2008 |
| 20090023219 | SPECIMEN GATHERING DEVICE AND METHOD OF USE - A kit is provided for gathering biological specimens. The kit generally comprises a self-contained specimen gathering device including a protective housing and a preservation solution. Also provided is a method of gathering specimens and a holistic method of deterring crime using the kit. | 01-22-2009 |
| 20090042303 | METHOD FOR MEASURING THE CONCENTRATION OF A GLYCOSAMINOGLYCAN ANTICOAGULANT - The invention provides an accurate, economical, automatable, high throughput method for the determination of the concentration of glycosaminoglycan anticoagulants, including low molecular weight heparin (LMWH) anticoagulants, in aqueous solutions. A method for cleaning a unit of manufacturing equipment used in the preparation of a LMWH to obtain an acceptable residual concentration of LMWH is further provided. | 02-12-2009 |
| 20090186416 | DILUENT WELLS PRODUCED IN CARD FORMAT FOR IMMUNODIAGNOSTIC TESTING - An immunodiagnostic test card includes a flat planar member and at least one dilution chamber that is supported by the flat planar member. The at least one dilution chamber can be disposed adjacent chambers used for testing a patient sample that are provided on the immunodiagnostic test card or can be provided separately. | 07-23-2009 |
| 20090233369 | METHOD FOR IMPROVING CHEMILUMINESCENT SIGNAL - The present invention is directed to compositions and methods for improving a chemiluminescent signal. In particular, a reaction buffer with an alkaline pH range of about 9 to 10 provides a maximal chemiluminescent intensity and longevity of luminol that is catalyzed by superoxide anions. The addition of carbonate to the reaction buffer provides an optimal signal to background ratio and stability of a chemiluminescent signal from luminol catalyzed by superoxide anions. The method includes preparing a buffer with an alkaline pH, combining the buffer with a working reagent to produce and detect a chemiluminescent signal. The working reagent includes luminol, a coumaric acid and a peroxide. The composition includes a buffer having a pH from about 9 to about 10, a stock reagent comprising luminol, a coumaric acid, a peroxide, and a second buffer having a pH of about 8.5. | 09-17-2009 |
| 20090305422 | METHODS AND REAGENTS FOR PRESERVATION OF DNA IN BODILY FLUIDS - Methods, systems and reagents are provided for preserving nucleic acids in a bodily fluid, such as urine, blood, blood serum, and amniotic fluid. The preservative includes an amount of at least one chelator enhancing component selected from the group consisting of lithium chloride, guanidine, sodium salicylate, sodium perchlorate, guanidine thiocyanate, and sodium thiocyanate in the range of from about 0.1M to about 2M and an amount of least one buffer component selected from the group consisting of Tris and HEPES. | 12-10-2009 |
| 20140179008 | BUFFER KIT AND METHOD OF GENERATING A LINEAR pH GRADIENT - A buffer kit includes a first eluent and second eluent. The first eluent solution includes at least four buffer salts where at least three of the four buffer salts are a monovalent buffer salt, have a net negative charge or a net neutral zwitterionic charge, and include a sulfonate group and an amine. The second eluent solution includes at least four buffer salts where at least three of the four buffer salts are a monovalent buffer salt, have a net negative charge or a net neutral zwitterionic charge, and include a sulfonate group and an amine. The first eluent solution has a first pH and the second eluent solution has a second pH where the first pH and second pH are different values. The buffer kit provides a linear pH gradient that forms an approximately straight line from at least the first pH to the second pH. | 06-26-2014 |
| 20150024502 | METHODS OF STABILIZING TOTAL ORGANIC CARBON (TOC) LEVELS IN NON-ACIDIFIED STANDARDS FOR TOC ANALYZERS AT ROOM TEMPERATURE - Methods for stabilizing reference standards used in total organic carbon (TOC) analysis of water and pharmaceutical samples are disclosed. The methods include adding a preservative to TOC reference standards. The preservative is selected from the group consisting of copper (II) sulfate and hydrogen sulfite. Compositions of the stabilized reference standards are also disclosed. | 01-22-2015 |
