| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 435257200 | Transformants | 34 |
| 20080206841 | Nucleic acid sequences from Chlorella vulgaris and uses thereof - Expressed Sequence Tags (ESTs) isolated from the unicellular green algae, | 08-28-2008 |
| 20100279390 | Methods for Transforming Eukaryotic Algae - Compositions and methods for genetically modifying algae or other photosynthetic eukaryotes to express an alcohol producing enzyme, such as pyruvate decarboxylase (PDC) and alcohol dehydrogenase (ADH) or any other enzymes that also synthesizes methanol, ethanol or butanol are provided. These enzymes are engineered to contain chloroplast targeting sequences which efficiently target xenotypic proteins to the chloroplast. Algae can be stably transformed with the compositions comprising chloroplast targeting constructs containing alcohol producing enzymes whereby the alcohol is produced in the chloroplast of the organism. | 11-04-2010 |
| 20110256613 | Designer proton-channel transgenic algae for photobiological hydrogen production - A designer proton-channel transgenic alga for photobiological hydrogen production that is specifically designed for production of molecular hydrogen (H | 10-20-2011 |
| 20110287525 | DILUTING EXHAUST GAS BEING SUPPLIED TO BIOREACTOR - There is provided a process of growing a phototrophic biomass in a reaction zone. The reaction zone includes an operative reaction mixture. The operative reaction mixture includes the phototrophic biomass disposed in an aqueous medium. Gaseous exhaust material is produced with a gaseous exhaust material producing process, wherein the gaseous exhaust material includes carbon dioxide. Reaction zone feed material is supplied to the reaction zone of a photobioreactor such that any carbon dioxide of the reaction zone feed material is received by the phototrophic biomass so as to provide a carbon dioxide-enriched phototrophic biomass in the aqueous medium. A discharge of the gaseous exhaust material from the gaseous exhaust material producing process is supplied to the reaction zone feed material and defines a gaseous exhaust material reaction zone supply. A supplemental gaseous dilution agent is supplied to the reaction zone feed material. The carbon dioxide concentration of the supplemental gaseous dilution agent is less than the carbon dioxide concentration of the gaseous exhaust material reaction zone supply which is supplied to the reaction zone feed material. The carbon dioxide-enriched phototrophic biomass disposed in the aqueous medium is exposed to photosynthetically active light radiation so as to effect photosynthesis. | 11-24-2011 |
| 20110287526 | PROCESS FOR GROWING BIOMASS BY MODULATING INPUTS TO REACTION ZONE BASED ON CHANGES TO EXHAUST SUPPLY - There is provided a process of growing a phototrophic biomass in a reaction zone. The reaction zone includes an operative reaction mixture. The operative reaction mixture includes the phototrophic biomass disposed in an aqueous medium. Gaseous exhaust material is produced with a gaseous exhaust material producing process, wherein the gaseous exhaust material includes carbon dioxide. Reaction zone feed material is supplied to the reaction zone such that any carbon dioxide of the reaction zone feed material is received by the phototrophic biomass so as to provide a carbon dioxide-enriched phototrophic biomass in the aqueous medium. A discharge of the gaseous exhaust material from the gaseous exhaust material producing process is supplied to the reaction zone feed material and defines a gaseous exhaust material reaction zone supply. The carbon dioxide-enriched phototrophic biomass disposed in the aqueous medium is exposed to photosynthetically active light radiation so as to effect photosynthesis. When an indication of a change in the molar rate of supply of carbon dioxide in the gaseous exhaust material reaction zone supply to the reaction zone feed material is sensed, at least one input to the reaction zone is modulated. The modulating of at least one input includes at least one of: (a) effecting or eliminating supply of, or modulating the intensity of, the photosynthetically active light radiation to which at least a fraction of the carbon dioxide-enriched phototrophic biomass is exposed, and (b) effecting, modulating, or eliminating the molar rate of supply, or commencing supply, of a nutrient supply to the reaction zone. | 11-24-2011 |
| 20120009656 | Methods and Compositions for the Recombinant Biosynthesis of N-Alkanes - The present disclosure identifies methods and compositions for modifying photoautotrophic organisms as hosts, such that the organisms efficiently convert carbon dioxide and light into n-alkanes, and in particular the use of such organisms for the commercial production of n-alkanes and related molecules. | 01-12-2012 |
| 20120015427 | ETHANOL PRODUCTION IN MICROORGANISMS - The present disclosure relates to methods and compositions for engineering photoautotrophic organisms to convert carbon dioxide and light into fatty acid esters and other molecules, including biofuels. The molecules are then secreted by the organism into a growth medium. | 01-19-2012 |
| 20120045821 | METHODS AND COMPOSITIONS FOR GENETIC ENGINEERING OF CYANOBACTERIA TO PRODUCE ETHANOL - Provided herein are compositions and methods for genetic engineering of cyanobacteria to produce ethanol. In one aspect, the present invention provides a polynucleotide construct comprising a copper ion inductive promoter and a sequence encoding a pyruvate decarboxylase (pdc) enzyme. In another aspect, the present invention provides a genetically engineered cyanobacterium comprising the polynucleotide construct of the invention, wherein the cyanobacterium is capable of producing ethanol after a period of fermentation. In yet another aspect, the present invention discloses a method of producing ethanol by genetically modifying cyanobacteria using the polynucleotide construct of the invention. | 02-23-2012 |
| 20120094362 | Production of Branched-Chain Alcohols by Photosynthetic Microorganisms - The present invention provides genes, polypeptides and expression constructs therefor, recombinant photosynthetic microorganisms, and method of use thereof, such as for the production of branched-chain alcohols (including 2-methyl-1-butanol, 3-methyl-1-butanol, and isobutanol) and derivatives thereof for a variety of uses. | 04-19-2012 |
| 20120122192 | Edible Oils and Food Compositions From Heterotrophic Microorganisms - The invention provides methods of manufacturing oils and oil-based products such as transportation fuels, industrial chemicals, edible oils, lubricants and plastics using sugar cane, sugar cane juice, corn steep liquor, corn starch or depolymerized cellulosic material as a feedstock for bioproduction processes. The disclosed processes utilize oil-bearing microbes as a food source and as a conversion technology to convert chemical energy produced by various fixed carbon sources into edible oils. | 05-17-2012 |
| 20120122193 | ENGINEERED CO2 FIXING MICROORGANISMS PRODUCING CARBON-BASED PRODUCTS OF INTEREST - The present disclosure identifies pathways and mechanisms to confer production of carbon-based products of interest such as ethanol, ethylene, chemicals, polymers, n-alkanes, isoprenoids, pharmaceutical products or intermediates thereof in photoautotrophic organisms such that these organisms efficiently convert carbon dioxide and light into carbon-based products of interest, and in particular the use of such organisms for the commercial production of ethanol, ethylene, chemicals, polymers, n-alkanes, isoprenoids, pharmaceutical products or intermediates thereof. | 05-17-2012 |
| 20120149092 | Ethanol Production in Microorganisms - The present disclosure relates to methods and compositions for engineering photoautotrophic organisms to convert carbon dioxide and light into fatty acid esters and other molecules, including biofuels. The molecules are then secreted by the organism into a growth medium. | 06-14-2012 |
| 20120164713 | GENETICALLY ENGINEERED MICROORGANISMS COMPRISING 4-HYDROXYBENZOYL-COA THIOESTERASES AND METHODS OF USING THE SAME FOR PRODUCING FREE FATTY ACIDS AND FATTY ACID DERIVATIVES - The described invention provides genetically engineered microorganisms, including photosynthetic microorganisms, expressing 4-hydroxybenzoyl-CoA thioesterases and methods of using the genetically engineered microorganisms for producing free fatty acids and/or fatty acid derivatives. | 06-28-2012 |
| 20120220021 | HERBICIDE RESISTANT ORGANISMS - Disclosed herein are transformed non-vascular photosynthetic organisms that are herbicide resistant, nucleotides and vectors useful in conducting such transformations, and transformed strains produced by such transformations. | 08-30-2012 |
| 20120288918 | SALT TOLERANT ORGANISMS - Disclosed herein are transformed non-vascular photosynthetic organisms that are salt tolerant, nucleotides and vectors useful in conducting such transformations, and transformed strains produced by such transformations. | 11-15-2012 |
| 20130078709 | Nucleic Acids Useful in the Manufacture of Oil - Novel gene sequences from microalgae are disclosed, as well as novel gene sequences useful in the manufacture of triglyceride oils. Also disclosed are sequences and vectors that allow microalgae to be cultivated on sugar cane and sugar beets as a feedstock. In some embodiments, the vectors are useful for the purpose of performing targeted modifications to the nuclear genome of heterotrophic microalgae. | 03-28-2013 |
| 20130089916 | Nucleic Acids Useful in the Manufacture of Oil - Novel gene sequences from microalgae are disclosed, as well as novel gene sequences useful in the manufacture of triglyceride oils. Also disclosed are sequences and vectors that allow microalgae to be cultivated on sugar cane and sugar beets as a feedstock. In some embodiments, the vectors are useful for the purpose of performing targeted modifications to the nuclear genome of heterotrophic microalgae. | 04-11-2013 |
| 20130143306 | Methods and Compositions for the Recombinant Biosynthesis of Fatty Acids and Esters - The present disclosure identifies methods and compositions for modifying photoautotrophic organisms, such that the organisms efficiently convert carbon dioxide and light into compounds such as esters and fatty acids. In certain embodiments, the compounds produced are secreted into the medium used to culture the organisms. | 06-06-2013 |
| 20130273638 | ENHANCED GENE EXPRESSION IN ALGAE - The invention provides eukaryotic unicellular algae engineered to express a nucleosome alteration protein fused to a protein with affinity to the DNA binding site acting in coordination. An example is a LexA-p300 fusion protein, where the p300 is derived from | 10-17-2013 |
| 20130280793 | CELL SYSTEMS AND METHODS FOR IMPROVING FATTY ACID SYNTHESIS BY EXPRESSION OF DEHYDROGENASES - The invention relates to methods for producing lipids such as fatty acid products in recombinant host cells engineered to express a non-native gene encoding a dehydrogenase. The recombinant microorganisms are able to proliferate at a higher rate as compared with microorganisms that do not express a non-native dehydrogenase gene, and cultures of microorganisms that are engineered for lipid production and that express a non-native dehydrogenase produce more lipid than cultures of control microorganisms that do not include a non-native dehydrogenase gene. | 10-24-2013 |
| 20130323823 | Tailored Oils - Recombinant DNA techniques are used to produce oleaginous recombinant cells that produce triglyceride oils having desired fatty acid profiles and regiospecific or stereospecific profiles. Genes manipulated include those encoding stearoyl-ACP desturase, delta 12 fatty acid desaturase, acyl-ACP thioesterase, ketoacyl-ACP synthase, and lysophosphatidic acid acyltransferase. The oil produced can have enhanced oxidative or thermal stability, or can be useful as a frying oil, shortening, roll-in shortening, tempering fat, cocoa butter replacement, as a lubricant, or as a feedstock for various chemical processes. The fatty acid profile can be enriched in midchain profiles or the oil can be enriched in triglycerides of the saturated-unsaturated-saturated type. | 12-05-2013 |
| 20140178973 | Cyanobacterium sp. Host Cell and Vector for Production of Chemical Compounds in Cyanobacterial Cultures - A cyanobacterial host cell, | 06-26-2014 |
| 20140256024 | Nucleic Acids Useful in the Manufacture of Oil - Novel gene sequences from microalgae are disclosed, as well as novel gene sequences useful in the manufacture of triglyceride oils. Also disclosed are sequences and vectors that allow microalgae to be cultivated on sugar cane and sugar beets as a feedstock. In some embodiments, the vectors are useful for the purpose of performing targeted modifications to the nuclear genome of heterotrophic microalgae. | 09-11-2014 |
| 20140273175 | System for Staged Inoculation of Multiple Cyanobacterial Photobioreactors for Commercial Scale Generation of Cyanobacteria Cultures - A method of rapid simultaneous inoculation of cyanobacteria to multiple commercial-scale closed photobioreactors for the production of a target molecule such as ethanol. | 09-18-2014 |
| 20140322799 | METABOLICALLY ENHANCED CYANOBACTERIUM WITH SEQUENTIALLY INDUCIBLE PRODUCTION GENES FOR THE PRODUCTION OF A FIRST CHEMICAL COMPOUND - This invention provides a metabolically enhanced cyanobacterium for the production of a chemical compound of interest, having at least two first production genes encoding first biocatalysts for the production of the first chemical compound. One of the two first production genes is under the transcriptional control of a first promoter for the first production gene, whereas the other of the two first production genes is under the transcriptional control of a second promoter for the first production gene. The first promoter and second promoter are separately inducible under different conditions and the at least two first biocatalysts catalyze the same chemical reaction. Metabolically enhanced cyanobacteria according to the present invention allow prolonged production of first chemical compounds. Further provisions of the present invention include, inter alia, a method for producing the metabolically enhanced cyanobacterium and a method for producing a first chemical compound by culturing the metabolically enhanced cyanobacterium. | 10-30-2014 |
| 20140370574 | Metabolically Enhanced Cyanobacterial Cell for the Production of Ethanol - A metabolically enhanced cyanobacterial cell for the production of ethanol is provided. The metabolically enhanced cyanobacterial cell for the production of ethanol comprises at least one recombinant gene encoding a pyruvate decarboxylase enzyme (Pdc) converting pyruvate to acetaldehyde, and at least one recombinant gene encoding a first Zn | 12-18-2014 |
| 20140370575 | GENETICALLY ENHANCED CYANOBACTERIA FOR THE PRODUCTION OF A FIRST CHEMICAL COMPOUND HARBOURING ZN2+, CO2+ OR NI2+ -INDUCIBLE PROMOTERS - One embodiment of the invention is directed to a genetically enhanced cyanobacterium for the production of a first chemical compound, comprising at least one first recombinant gene encoding a first biocatalyst for the production of the first chemical compound, wherein the gene is under the transcriptional control of a Co | 12-18-2014 |
| 20140377847 | Tailored Oils - Recombinant DNA techniques are used to produce oleaginous recombinant cells that produce triglyceride oils having desired fatty acid profiles and regiospecific or stereospecific profiles. Genes manipulated include those encoding stearoyl-ACP desturase, delta 12 fatty acid desaturase, acyl-ACP thioesterase, ketoacyl-ACP synthase, and lysophosphatidic acid acyltransferase. The oil produced can have enhanced oxidative or thermal stability, or can be useful as a frying oil, shortening, roll-in shortening, tempering fat, cocoa butter replacement, as a lubricant, or as a feedstock for various chemical processes. The fatty acid profile can be enriched in midchain profiles or the oil can be enriched in triglycerides of the saturated-unsaturated-saturated type. | 12-25-2014 |
| 20150104854 | METABOLICALLY ENGINEERED METHANOTROPHIC, PHOTOTROPHIC MICROORGANISMS - This disclosure relates to the engineering of phototrophic microorganisms for conversion of alkanes into higher-value products. Recombinant phototrophic organisms such as cyanobacteria can be engineered, optionally in a modular format, to express enzymes involved in converting methane to methanol, methanol to formaldehyde, formaldehyde to central metabolic pathway intermediates, and such intermediates to n-butanol. | 04-16-2015 |
| 20150353941 | Genetically Modified Biological Cells - The present invention is based, in part, on our discovery of a way to configure expression cassettes so that the expression of a selectable marker protein, which is critical for the growth or survival of a cell, also results in the expression of a protein of interest in a biological cell. Accordingly, in one aspect, the invention features a genetically modified cell (e.g., a bacterial cell) that includes a chromosomally integrated or cytoplasmic expression cassette that includes a first nucleic acid sequence encoding a protein of interest an a second nucleic acid sequence encoding a selectable marker protein. The regulatory sequence (e.g., the sequence encoding a functional promoter) that drives expression of the required selectable marker protein also drives expression of the protein of interest. For that reason, we may refer to their expression as being “linked” or “functionally coupled.” | 12-10-2015 |
| 20160053273 | ALGAL ELONGASE 6 - Provided herein are exemplary isolated nucleotide sequences encoding polypeptides having elongase activity, which utilize fatty acids as substrates. | 02-25-2016 |
| 20160168580 | EXPRESSION VECTOR FOR CYANOBACTERIA | 06-16-2016 |
| 20160186196 | METHOD AND COMPOSITION FOR GENERATING PROGRAMMED CELL DEATH RESISTANT ALGAL CELLS - The present invention provides transgenic algal cells resistant to programmed cell death (PCD) and methods and compositions useful in generating such cells. Specifically, the invention utilizes expression of one or more mammalian anti-apoptotic genes in algal cells to promote resistance to PCD, which is useful for stress tolerance and increased cell viability and biomass production during cultivation. | 06-30-2016 |
| 20160251676 | SALT TOLERANT ORGANISMS | 09-01-2016 |
