Class / Patent application number | Description | Number of patent applications / Date published |
435182000 | Enzyme or microbial cell is entrapped within the carrier (e.g., gel, hollow fibre) | 36 |
20090004718 | Antioxidant Fermenting Microorganism Agent Reducing Volatile Organic Compounds From Polyurethane Foam, and Urethane Foam Comprising the Same - Disclosed is an antioxidant fermenting microorganism agent and a polyurethane foam including the same. The antioxidant fermenting microorganism agent is used to generate a substance that is capable of reducing an amount of volatile organic compounds generated from the polyurethane foam and has an antimicrobial ability. The polyurethane foam containing the antioxidant fermenting microorganism according to the present invention can be used as the material for the interior of a vehicle to protect humans from noxious substances causing sick car syndrome. | 01-01-2009 |
20090061499 | METHOD FOR INDUSTRIAL PRODUCTION OF BIOCATALYSTS IN THE FORM OF ENZYMES OR MICROORGANISMS IMMOBILIZED IN POLYVINYL ALCOHOL GEL, THEIR USE AND DEVICES FOR THEIR PRODUCTION - A method for the industrial production of the biocatalysts with biologically active material in the form of immobilized enzymes or microorganisms which are immobilized into the polyvinyl alcohol gel, and their use based on the fact, that the active biological material, formed by the mixture of free native or pretreated (aggregated) enzyme catalyst, or production microorganism, or part of them, and the polyvinyl alcohol gel, is used for their industrial production, the mixture is gelated and shaped in a stream of drying air at the temperature of 800 C to 150 C, considering the extent of the biologically active material, at the biocatalyst geometrical ratio of the surface to the volume kept larger than 7 mm‘l, and consequently thus prepared biocatalysts can be cultivated or stored and then use in biotechnological processes in the conditions, which ensure given biotechnological process higher productivity, higher production and enzymatic stability, long-term and repeated usage or definable process control with consequence easy separation of the biocatalyst. The industrial production device, providing optimization of the biological carrier volume and surface in dependence on biologically active material extent, consisting of a casting mechanism ( | 03-05-2009 |
20090075354 | NANOFIBER STRUCTURES FOR SUPPORTING BIOLOGICAL MATERIALS - The present invention relates generally to nanofiber structures designed to support, entrap, entangle, preserve, and/or retain one or more biological materials. More specifically, the present invention relates to nanofiber matrix structures made from at least two different types of nanofibers that are designed to support, entrap, entangle, preserve, and/or retain one or more biological materials. | 03-19-2009 |
20090209020 | collagenous matrix with improved porosity and tensile strength and preparation method therefore by using mechanical stimulation system - The present invention relates to a method of preparing a collagen matrix with increased porosity and tensile strength by using mechanical stimulation system. More specifically, in the present invention, the cell-populated gel is being cultured under the condition that the physical forces is loaded for causing the matrix to move periodically and discontinuously. Resulting collagen matrix can be used for preparing an artificial skin or organs. Furthermore, this collagen matrix can be used as fillers for esthetic or therapeutic purposes. | 08-20-2009 |
20090269824 | Apparatus and method for fabricating Micro-Capsule - The present invention relates to an apparatus and a method for fabricating a microcapsule, more particularly to an apparatus and a method for fabricating a microcapsule, which enable to encapsulate uniform cell number in a microcapsule through cell distribution, improve cell viability in the microcapsule through fluid exchange, and ensure uniform microcapsule size. | 10-29-2009 |
20090317887 | Charged initiator polymers and methods of use - Positively-charged initiator polymers having a polymerization initiator group and a cationic portion are provided. The initiator polymers can be used with a polymerizable material for the formation of a polymeric matrix on a surface. The initiator polymers are particularly useful for cell encapsulation using macromers. | 12-24-2009 |
20100028971 | Carriers for Enzyme or Cell Immobilization and Immobilization Method Using the Carriers - The invention discloses a carrier made from an organic foam having open pores for enzymes or cells immobilization and the methods for preparing immobilized enzymes or cells. The invention uses flocculation and crosslinking technology to immobilize enzyme protein or cells on the organic foam material having open pores. The resultant immobilized products have larger specific surface area, higher specific activity and can be made into various shapes. | 02-04-2010 |
20100041123 | IMMOBILIZED ENZYMES AND USES THEREOF - Disclosed are bioanodes comprising a quaternary ammonium treated Nafion® polymer membrane and a dehydrogenase incorporated within the treated Nafion® polymer. The dehydrogenase catalyzes the oxidation of an organic fuel and reduces an adenine dinucleotide. The ion conducting polymer membrane lies juxtaposed to a polymethylene green redox polymer membrane, which serves to electro-oxidize the reduced adenine dinucleotide. The bioanode is used in a fuel cell to produce high power densities. | 02-18-2010 |
20100120117 | Polymer Coating of Cells - Polymers and methods of making them are described. The polymers may be used to coat living cells. The polymer-coated cells are useful in cell therapy applications. | 05-13-2010 |
20100136649 | Encapsulation of Cells in Biologic Compatible Scaffolds by Coacervation of Charged Polymers - This invention relates to a method for the encapsulation of cells in biologic compatible three dimensional scaffolds and the use of such cells encapsulated in a scaffold. The cells are embedded in a charged polymer that is complex coacervating with an oppositely charged polymer within biologic compatible scaffolds. The polymer complex embedding the cells is forming an ultra thin membrane on the surface of the three dimensional scaffold. | 06-03-2010 |
20100144007 | APPARATUS AND METHODS FOR LOADING SOFT MATERIALS - The present invention provides an apparatus for loading soft materials and methods for using the same. In some embodiments, the apparatus is a gearless mechanical loading apparatus which converts a rotational movement of one end of a first element into an arc of a circle movement of the other end of the first element; and converts the arc of a circle movement of the other end of the first element into a precision two-dimensional lateral movement of a second element. | 06-10-2010 |
20100209989 | Entrapping immobilization pellets and process for producing the same - The present invention produces entrapping immobilization pellets which have high pellet strength and retain high and stable microbial activity (nitrification activity) even if a low concentration of a material involved in immobilization (such as an immobilizing material or polymerization initiator) used. The entrapping immobilization pellets in which microorganisms are entrapped and immobilized in an immobilizing material comprise a filler having a plate-like and/or needle-like crystal structure in the immobilizing material. | 08-19-2010 |
20110117623 | DYNAMIC THERMORESPONSIVE NANOPARTICLES FOR STABILIZATION OF ENZYMES AT HIGH TEMPERATURES - The present invention provides a thermoresponsive nanoparticle useful for the stabilization of enzymes in environments having a temperature greater than thirty degrees Centigrade. The thermoresponsive nanoparticle has (a) a functionalized enzyme conjugate having one or more enzymes or biological catalysts, the enzymes or biological catalysts are modified with palmitic acid N-hydroxysuccinimide ester and acryclic acid N-hydroxysuccinimide ester, and (b) a thermally responsive polymer, wherein the functionalized enzyme conjugate is encapsulated within the thermally responsive polymer. A nanocatalyst is provided that has one or more proteins. The proteins are covalently immobilized and encapsulated within a thermally responsive polymer shell. The proteins are one or more enzymes or biological catalysts. A method for protecting the proteins is also set forth. | 05-19-2011 |
20110287509 | STABLE BIOCATALYSTS OF PENICILLIN ACYLASE AS GEL AGGREGATES AND THE PROCESS OF MANUFACTURE THEREOF - The present invention provides a stable and viable biocatalyst with high activity and operational stability and method of immobilization thereof. The immobilization process is based on the principle of entrapment of partially purified enzyme precipitate which is simultaneously aggregated by cross linking agent like glutaraldehyde and further entrapped in a combination of natural polymer like gelatin and synthetic polymer like polyvinyl alcohol with effective gelation under mild conditions of temperature and pH, resulting in a stable biocatalyst. The enzymes immobilized by the above process include Penicillin acylase from r | 11-24-2011 |
20120252090 | HEAT RESISTANT BIOACTIVE COMPOSITION - A process for stabilizing a bioactive composition includes forming hydrogel matrix pores around protein molecules and reducing a water content within the hydrogel matrix pores while keeping the protein molecules biologically active. | 10-04-2012 |
20120301942 | CHIP PROVIDED WITH FILM HAVING HOLE PATTERN WITH THE USE OF THERMORESPONSIVE POLYMER AND METHOD OF PRODUCING THE SAME - A chip useful for treating cells and the like which has a mechanism and a structure wherein the size of a hole pattern is arbitrarily changed so that cells can easily move in and get out from the hole in scattering or collecting cells but can hardly get out from the hole during washing or antigen-stimulation. The chip comprises a crosslinked product of a temperature-responsive polymer as a constituting member and being provided with a film having a hole pattern on the surface of a baseboard. A method of producing the chip comprises applying a composition containing a crosslinkable temperature-responsive polymer on the surface of a baseboard to thereby form a coating film, crosslinking the coating film to thereby form the crosslinked product as described above and then forming a hole pattern on the coating film of the crosslinked product. | 11-29-2012 |
20130005016 | POLYMERS COMPRISING A MAJORITY OF AMPHIPHILIC MONOMERS INTENDED FOR TRAPPING AND MANIPULATIONF MEMBRANE PROTEINS - The invention relates to an amphiphilic polymer comprising at least 75% of amphiphilic monomers of formula (I), the average molar mass of the polymer being between 800 and 100 000, and also water-soluble complexes between the polymer according to the invention and a hydrophobic or amphiphilic compound, in particular a membrane protein, a concentrated aqueous solution of one or more such complex(es), a product comprising one or more such complex(es) attached to a substrate by means of the polymer according to the invention, and various uses of these products. | 01-03-2013 |
20130040357 | Hydrogel Precursor Formulation and Production Process Thereof - The present invention relates to a hydrogel precursor formulation, its process of production as well as a kit comprising said formulation and a method of production of a hydrogel using said formulation. The precursor formulation comprises at least one structural compound, preferably vinyl sulfone (acrylated branched) poly(ethylene glycol), and at least one linker compound, preferably a peptide with two cysteines, wherein said structural compound and said linker compound are polymerizable by a selective reaction between a nucleophile and a conjugated unsaturated bond or group. The precursor formulation is in the form of a powder. | 02-14-2013 |
20130157336 | METHODS AND COMPOSITIONS FOR OXIDIZING BISPHENOL A - Disclosed are methods, compositions and kits pertaining to polymer coatings that entrap enzymes, specifically enzymes capable of degrading bisphenol A. | 06-20-2013 |
20130196405 | POROUS FIBER, METHODS OF MAKING THE SAME AND USES THEREOF - There is provided a porous fiber having a core-shell configuration, wherein the pores on the fiber are configured to encapsulate and thereby retain a biological material therein. | 08-01-2013 |
20130224826 | BIOACTIVE COMPOSITION INCLUDING STABILIZED PROTEIN AND PROCESS FOR PRODUCING THE SAME - A bioactive composition includes a porous hydrogel matrix. At least one protein is immobilized in the porous hydrogel matrix forming a hydrogel protein composite that is stable in an organic solvent. A process for stabilizing a bioactive composition includes the steps of: forming hydrogel matrix pores around protein molecules and reducing water content within the hydrogel matrix pores forming a hydrogel protein composite that is stable in an organic solvent. | 08-29-2013 |
20130244301 | Dynamic Thermoresponsive Nanoparticles For Stabilization Of Enzymes At High Temperatures - The present invention provides a thermoresponsive nanoparticle useful for the stabilization of enzymes in environments having a temperature greater than thirty degrees Centigrade. The thermoresponsive nanoparticle has (a) a functionalized enzyme conjugate having one or more enzymes or biological catalysts, the enzymes or biological catalysts are modified with palmitic acid N-hydroxysuccinimide ester and acryclic acid N-hydroxysuccinimide ester, and (b) a thermally responsive polymer, wherein the functionalized enzyme conjugate is encapsulated within the thermally responsive polymer. A nanocatalyst is provided that has one or more proteins. The proteins are covalently immobilized and encapsulated within a thermally responsive polymer shell. The proteins are one or more enzymes or biological catalysts. A method for protecting the proteins is also set forth. | 09-19-2013 |
20130267004 | POLYSILICATE-POLYSILICONE ENZYME IMMOBILIZATION MATERIALS - The present invention generally relates to improvements in enzyme immobilization, particularly for use in the field of carbon dioxide capture and sequestering. It has been discovered that the utilization of sol-gel processes to immobilize enzymes in polysilicate-polysilicone copolymer coatings and particles, and the deposition of these coatings on solid state supports or use of suspensions of these particles, provides significant benefits for use in industrial applications involving enzymatic catalysts. | 10-10-2013 |
20130288330 | CAPSULE FOR NON-FERROUS METAL COLLECTION AND METHOD OF COLLECTING NON-FERROUS METAL - Provided are: a capsule for non-ferrous metal collection that can collect a non-ferrous metal; and a method for collecting a non-ferrous metal using same. The capsule for non-ferrous metal collection comprises capsule contents and a covering section covering the capsule contents, and collects a non-ferrous metal within the capsule for non-ferrous metal collection by means of the capsule for non-ferrous metal collection being immersed in a solution containing a non-ferrous metal. | 10-31-2013 |
20140045241 | MICELLAR POLYSILOXANE ENZYME IMMOBILIZATION MATERIALS - The present invention generally relates to immobilized enzymes for use in carbon capture and other systems; particularly, materials used to immobilize carbonic anhydrase are disclosed. | 02-13-2014 |
20140178964 | Cell-Friendly Inverse Opal Hydrogels for Cell Encapsulation, Drug and Protein Delivery, and Functional Nanoparticle Encapsulation - The invention provides polymer scaffolds for cell-based tissue engineering. | 06-26-2014 |
20140248681 | MICROCAPSULES AND CONCRETE CONTAINING THE SAME - Microcapsules, for inclusion in concrete, adapted to reduce the area of a defect by at least 45% in said concrete once a quantity of said microcapsules has ruptured, said microcapsules each comprising: a polymeric shell encapsulating a liquid core, wherein the polymeric shell comprises a substantially impermeable polymer layer and the liquid core comprises carbonatogenic bacterial spores, and optionally bacterial nutrients, dispersed in a liquid medium. Also disclosed is a concrete composition comprising a quantity of such microcapsules, and a method of reducing the area of a defect in concrete. | 09-04-2014 |
20140322787 | METHOD FOR MANUFACTURING IN VITRO VASCULARIZED TISSUE - The present invention relates to a method for manufacturing an in vitro vascularized tissue, which enables obtaining the in vitro vascularized tissue by inducing in vitro angiogenesis in a tissue using vascular cells, for use in in vitro research of diseases in vascularized tissues and developing a treatment. The method for manufacturing the in vitro vascularized tissue comprises the steps of: supplying a hydrogel to cover the vascularized tissue cells; molding the same to form a supply hole, which is separated from the vascularized tissue cells, on the upper side of the hydrogel; and supplying vascular cells to the supply hole. | 10-30-2014 |
20140349367 | Hydrolytically Degradable Micellar Hydrogels - Degradable and biologically inert hydrogel networks are described. The hydrogel networks are crosslinked and based on a biocompatible polymer that is chain extended with hydrophobic segments that include no more than 5 hydrophobic monomers to form a macromonomer that is then crosslinked to form a network that includes individual micelles throughout the crosslinked network. The hydrophobic segments of the macromonomer as well as other potentially toxic materials such as crosslink initiators can be sequestered in the micelles to better control degradation characteristics of the network as well as prevent toxicity to developing cellular structures of the network. | 11-27-2014 |
20150050712 | POLYSILICATE-POLYSILICONE ENZYME IMMOBILIZATION MATERIALS - The present invention generally relates to improvements in enzyme immobilization, particularly for use in the field of carbon dioxide capture and sequestering. It has been discovered that the utilization of sol-gel processes to immobilize enzymes in polysilicate-polysilicone copolymer coatings and particles, and the deposition of these coatings on solid state supports or use of suspensions of these particles, provides significant benefits for use in industrial applications involving enzymatic catalysts. | 02-19-2015 |
20150099288 | POROUS MEMBRANE HAVING IMMOBILIZED ENZYME, POROUS MEMBRANE COMPOSITE INCLUDING THE SAME, AND PREPARATION METHOD THEREOF - Disclosed herein is a porous membrane having an immobilized enzyme wherein the enzyme is immobilized within pores which are three-dimensionally connected to each other. The porous membrane having the immobilized enzyme is three-dimensionally crosslinked in a molecular level wherein nanopores of 5 to 100 nm are interconnected, so that the immobilized enzyme may be in contact with a reactant in all directions, and the reaction solution may be easily diffused, thereby proceeding with the catalytic reaction fast and conveniently without deterioration of material transport. | 04-09-2015 |
20150099289 | CARBONIC ANHYDRASE XEROGEL PARTICLES - The present invention generally relates to carbonic anhydrase xerogel particles comprising a polysilicate-polysilicone copolymer and carbonic anhydrase. The carbonic anhydrase xerogel particles can be used for carbon dioxide capture. | 04-09-2015 |
20150140634 | METHOD FOR PRODUCING A POLYMER PRODUCT FROM MULTIDIMENSIONAL AGGREGATED COMPONENTS AS BARRIER OR CARRIERS OF LIVING MICROBIAL CELLS AND BIOLOGICAL BARRIERS IN PLASTIC AND TEXTILE - This invention relates to a polymer product comprising the components consisting of a polymer in form of granules; a multidimensional structure containing amphiphilic molecules, such as lipids, surfactants or polymers, wherein said polymer product has an active and/or passive oxygen or CO | 05-21-2015 |
20160009596 | MICROCAPSULES AND CONCRETE CONTAINING THE SAME | 01-14-2016 |
20160032270 | APPARATUS AND PROCESS FOR PRODUCTION OF AN ENCAPSULATED CELL PRODUCT - A process for production of an encapsulated cell product, the process comprises the steps of concentrating cells from a propagation medium using a tangential flow filtration system. Mixing the concentrated cells with an encapsulation medium to form a cell encapsulation mixture. Polymerizing, gelling, or cross-linking the cell encapsulation mixture to form an encapsulated cell product. | 02-04-2016 |
20220135962 | METHODS AND MATERIALS FOR BIOLOGICAL IMMOBILIZATION IN MICROFLUIDICS - The present invention is directed to synthesizing and using fluid-insoluble material complexes that capture biologicals and remove them from samples in microscopic scale fluids, such as in droplets, wells, and micro-wells. The present invention also pertains to the option of detecting the captured biologicals, to the option of modifying the captured biologicals, and to the option of controllably releasing the captured biologicals. | 05-05-2022 |