Class / Patent application number | Description | Number of patent applications / Date published |
435137000 | Sugar acid having five or more carbon atoms (i.e., aldonic, keto-aldonic, or saccharic acid) | 16 |
20080254523 | Methods for the Production of Products in Host Cells - The invention provides methods and host cells for the production of ascorbic acid intermediates. The invention also provides host cells having a modification in a polynucleotide that uncouples the catabolic pathway from the oxidative pathway by deleting the encoding for an endogenous enzymatic activity that phosphorylates D-glucose at its 6th carbon and/or a polynucleotide that has deleted the encoding for endogenous enzymatic activity that phosphorylates D-gluconate at its 6th carbon. Such host cells are used for the production of products, such as, ascorbic acid intermediates. Nucleic acid and amino acid sequences with inactivated enzymatic activity which phosphorylates D-glucose at its 6th carbon and inactivated enzymatic activity which phosphorylates D-gluconate at its 6th carbon are provided. | 10-16-2008 |
20110003353 | Multimeric Oxidoreductases - The present invention concerns multimeric oxidoreductase complexes which function in the enzymatic conversion of a carbon substrate, said complexes having a dehydrogenase subunit and a cytochrome C subunit. The invention further relates to polynucleotides coding for the multimeric complexes and methods of use thereof. | 01-06-2011 |
20110111471 | NOVEN THERMOSTABLE GLUCONATE DEHYDRATASE AND USE THEREOF - The present invention relates to a novel thermostable gluconate dehydratase from the thermoacidophilic archaeon | 05-12-2011 |
20110124065 | CELLULAR PRODUCTION OF GLUCARIC ACID - The invention relates to the production of glucuronic and glucaric acid in cells through recombinant expression of myo-inositol 1-phosphate synthase, myo-inositol oxygenase and uronate dehydrogenase. Cloning and characterization of the gene encoding uronate dehydrogenase is also disclosed. | 05-26-2011 |
20120064585 | Increased Heterologous Fe-S Enzyme Activity in Yeast - Yeast strains were engineered that have increased activity of heterologous proteins that require binding of an Fe—S cluster for their activity. The yeast strains have reduced activity of an endogenous Fe—S protein. Activities of heterologous fungal or plant 2Fe-2S dihydroxy-acid dehydratases and Fe—S propanediol dehydratase reactivase were increased for increased production of products made using biosynthetic pathways including these enzymes, such as valine, isoleucine, leucine, pantothenic acid (vitamin B5), isobutanol, 2-butanone and 2-butanol. | 03-15-2012 |
20130071894 | GLUCOSE VALVE AND OTHER METABOLITE VALVES - Aspects of the invention relate to the design and construction of Metabolite Valves, such as Glucose Valves, that can be used to divert metabolites from endogenous pathways toward alternative pathways in a cell. | 03-21-2013 |
20130084612 | RECOMBINANT ESCHERICHIA COLI PRODUCING D-XYLONIC ACID FROM D-XYLOSE AND METHOD FOR PRODUCING D-XYLONIC ACID USING THE SAME - Disclosed herein is a recombinant | 04-04-2013 |
20130196396 | EXTRACELLULAR ALDONOLACTONASE - The present disclosure relates to hydrolysis of hexose-δ-lactones by use of an | 08-01-2013 |
20140193870 | EXTRACELLULAR ALDONOLACTONASE - The present disclosure relates to hydrolysis of hexose-δ-lactones by use of an | 07-10-2014 |
20140295508 | METHODS FOR PREPARING 2,5-FURANDICARBOXYLIC ACID - Provided are methods of producing 2,5-furandicarboxylic acid (FDCA) from renewable sources such as seaweed, alginate, oligoalginate, pectin, oligopectin, polygalacturonate, galacturonate, and/or oligogalacturonate. The sugars in the renewable sources can be converted into one or more intermediates such as 4-deoxy-L-erythro-5-hexoseulose uronate (DEHU), 4-deoxy-L-threo-5-hexosulose uronate (DTHU), 5-hydroxymethyl furfural (HMF), 2,5-dihydroxymethyl furan (DHMF), and 5-formyl-2-furancarboxylic acid (FFA), which can be converted into FDCA by dehydration and cyclization to produce 5-formyl-2-furancarboxylic acid (FFA), followed by oxidation to produce FDCA. DEHU or DTHU may also be converted into FDCA by oxidation to produce 2,3-dihydroxy-5-oxohexanedioic acid (DOHA), which then undergoes dehydration and cyclization to produce FDCA. | 10-02-2014 |
20150010969 | Method for Producing Glucaric Acid - The disclosure provides a method for creating a transformant having significantly improved glucaric acid-producing capability and a method for efficiently producing glucaric acid using the transformant. | 01-08-2015 |
20150093794 | CELLULAR PRODUCTION OF GLUCARIC ACID - The invention relates to the production of glucuronic and glucaric acid in cells through recombinant expression of myo-inositol 1-phosphate synthase, myo-inositol oxygenase and uronate dehydrogenase. Cloning and characterization of the gene encoding uronate dehydrogenase is also disclosed. | 04-02-2015 |
435138000 | Alpha-ketogulonic acid (i.e., 2-ketogulonic acid) | 4 |
20110256595 | BIOFUEL PRODUCTION - Methods, enzymes, recombinant microorganism, and microbial systems are provided for converting polysaccharides, such as those derived from biomass, into suitable monosaccharides or oligosaccharides, as well as for converting suitable monosaccharides or oligosaccharides into commodity chemicals, such as biofuels. Commodity chemicals produced by the methods described herein are also provided. Commodity chemical enriched, refinery-produced petroleum products are also provided, as well as methods for producing the same. | 10-20-2011 |
20120064586 | Multimeric Oxidoreductases - The present invention concerns multimeric oxidoreductase complexes which function in the enzymatic conversion of a carbon substrate, said complexes having a dehydrogenase subunit and a cytochrome C subunit. The invention further relates to polynucleotides coding for the multimeric complexes and methods of use thereof. | 03-15-2012 |
20130203135 | MULTIMERIC OXIDOREDUCTASES - The present invention concerns multimeric oxidoreductase complexes which function in the enzymatic conversion of a carbon substrate, said complexes having a dehydrogenase subunit and a cytochrome C subunit. The invention further relates to polynucleotides coding for the multimeric complexes and methods of use thereof. | 08-08-2013 |
20140170718 | MULTIMERIC OXIDOREDUCTASES - The present invention concerns multimeric oxidoreductase complexes which function in the enzymatic conversion of a carbon substrate, said complexes having a dehydrogenase subunit and a cytochrome C subunit. The invention further relates to polynucleotides coding for the multimeric complexes and methods of use thereof. | 06-19-2014 |