Class / Patent application number | Description | Number of patent applications / Date published |
435107000 | Proline; hydroxyproline; histidine | 71 |
20080261278 | METHOD FOR PRODUCING L-AMINO ACID USING BACTERIA BELONGING TO THE GENUS ESCHERICHIA - There is provided a method for producing L-threonine, L-valine, L-proline, L-leucine, L-methionine and L-arginine using a bacterium belonging to the genus | 10-23-2008 |
20080293109 | Methods for degrading or converting plant cell wall polysaccharides - The present invention relates to methods for converting plant cell wall polysaccharides into one or more products, comprising: treating the plant cell wall polysaccharides with an effective amount of a spent whole fermentation broth of a recombinant microorganism, wherein the recombinant microorganism expresses one or more heterologous genes encoding enzymes which degrade or convert the plant cell wall polysaccharides into the one or more products. The present invention also relates to methods for producing an organic substance, comprising: (a) saccharifying plant cell wall polysaccharides with an effective amount of a spent whole fermentation broth of a recombinant microorganism, wherein the recombinant microorganism expresses one or more heterologous genes encoding enzymes which degrade or convert the plant cell wall polysaccharides into saccharified material; (b) fermenting the saccharified material of step (a) with one or more fermenting microoganisms; and (c) recovering the organic substance from the fermentation. | 11-27-2008 |
20090068711 | Method For The Production Of L-Amino Acids Using Strains From The Enterobacteriacea Family - The invention relates to a method for the production of L-amino acids by fermentation of recombinant microorganisms of the Enterobacteriaceae family, characterized in that a) the microorganisms producing the desired L-amino acid and wherein the lamB-gene or nucleotide sequence coding for the gene product maltoporin is amplified, particularly overexpressed, are cultivated in a medium in conditions enabling the desired L-amino acid to be enriched in the medium or in cells, and b) the desired L-amino acid is isolated, wherein constituents of the fermentation broth and/or biomass remain in the entirety thereof or in parts thereof (=0 bis 100%) in the isolated product or are fully removed. | 03-12-2009 |
20090081738 | Method for Producing an L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family Having Expression of the bolA Gene Attenuated - The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genus | 03-26-2009 |
20090087886 | METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF THE sfmACDFH-fimZ CLUSTER OR THE fimZ GENE - The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus | 04-02-2009 |
20090098621 | METHOD FOR PRODUCING AN L-AMINO ACID USING BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF A GENE CODING FOR SMALL RNA - The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus | 04-16-2009 |
20090104667 | L-AMINO ACID-PRODUCING MICROORGANISM AND A METHOD FOR PRODUCING AN L-AMINO ACID - An L-amino acid is produced by culturing a microorganism which belongs to the family Enterobacteriaceae and is able to produce an L-amino acid, wherein the bacterium has been modified to enhance orotate phosphoribosyltransferase activity is enhanced, in a medium to produce and cause accumulation of an L-amino acid in the medium or cells, and collecting the L-amino acid from the medium or the cells. | 04-23-2009 |
20090117623 | METHOD FOR PRODUCING L-AMINO ACIDS BY FERMENTATION USING BACTERIA HAVING ENHANCED EXPRESSION OF XYLOSE UTILIZATION GENES - A method for producing an L-amino acid, such as L-histidine, L-threonine, L-lysine, L-glutamic acid, and L-tryptophan, using bacterium belonging to the genus | 05-07-2009 |
20090130723 | Methods for Purifying Amino Acids - In the method for separating and purifying histidine from a culture containing the amino acid, the culture containing histidine and microbial cells is charged onto the top of a column filled with a carrier particle whose particle size is 350 μm or more and which has an ability to adsorb histidine and then an eluent is passed through the column whereby accomplishing the separation and purification of histidine, and preferably in the step mentioned above, a strong acid cation exchange resin is employed as a carrier particle whereby accomplishing the separation and purification of histidine. | 05-21-2009 |
20090137010 | METHOD FOR PRODUCING AMINO ACIDS USING BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY - A method for producing an L-amino acid is described, for example, L-phenylalanine and L-histidine, by fermentation using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified by attaching a DNA fragment able to be transcribed encoding the peptide represented in SEQ ID NO: 2, or a variant thereof, particularly a portion of the ssrA gene, to the 3′-end of gene encoding for the bacterial enzyme, which influences on the L-amino acid biosynthesis, such as chorismate mutase/prephenate dehydrogenase or phosphoglucose isomerase. | 05-28-2009 |
20090137011 | METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF THE rcsA GENE - The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus | 05-28-2009 |
20090170169 | METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF THE rspAB OPERON - The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus | 07-02-2009 |
20090209011 | Method for Producing an L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family With Enhanced Expression of the fucPIKUR Operon - The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genus | 08-20-2009 |
20090215129 | Method for Producing an L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family Having Expression of the leuO Gene Attenuated - The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genus | 08-27-2009 |
20090215130 | L-AMINO ACID PRODUCING BACTERIUM AND METHOD OF PRODUCING L-AMINO ACID - An L-amino acid is produced by culturing an L-amino acid-producing bacterium which belongs to the Enterobacteriaceae family and which has been modified so that the activity of an iron transporter is increased by enhancing expression of one or more genes of the following genes: tonB gene, fepA gene, and fecA. | 08-27-2009 |
20090221043 | MUTANT OF THE PROB GENE FROM CORYNEFORM BACTERIA - The invention relates to mutated variants of the proB gene from coryneform bacteria, which encode γ-glutamyl kinase, and to processes for fermentative production of L-proline using bacteria which contain this mutation. | 09-03-2009 |
20090239266 | Method for Producing a Non-Aromatic L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family Having Expression of the csrA Gene Attenuated - The present invention provides a method for producing a non-aromatic L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genus | 09-24-2009 |
20090239267 | Method for Producing an L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family With Attenuated Expression of the cpxR Gene - The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus | 09-24-2009 |
20090269819 | METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF ANY OF THE cynT, cynS, cynX OR cynR GENE OR COMBINATION THEREOF - The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus | 10-29-2009 |
20090275089 | Mutant Phosphoribosylpyrophosphate Synthetase and Method for Producing L-Histidine - The present invention relates to a mutant bacterial PRPP synthetase which is resistant to feedback by purine nucleotides, and a method for producing L-histidine using the bacterium of the Enterobacteriaceae family wherein the L-amino acid productivity of said bacterium is enhanced by use of the PRPP synthetase which is resistant to feedback by purine nucleotides, coded by the mutant prsA gene. | 11-05-2009 |
20090286290 | METHOD FOR PRODUCING AN L-AMINO ACID - A microorganism which has an L-amino acid producing ability and has been modified so that succinate dehydrogenase activity and α-ketoglutarate dehydrogenase activity are decreased is cultured in a medium to produce and accumulate an L-amino acid in the medium or cells of the microorganism, and the L-amino acid is collected from the medium or cells to produce the L-amino acid. | 11-19-2009 |
20090291477 | METHODS FOR OBTAINING CRYSTALS OF A BASIC AMINO ACID HYDROCHLORIDE - The present invention provides a method for separating and obtaining a basic amino acid hydrochloride from a basic amino acid fermentation broth or an enzyme reaction solution which enzyme reaction is catalyzed by viable microbial cells which are able to produce a basic amino acid, each containing sulfate ions, wherein product yields and qualities are almost the same and are secured more easily, as compared with the conventional technique. The method may include the steps of adding a metal chloride such as calcium chloride, potassium chloride, magnesium chloride, and barium chloride to the basic amino acid fermentation broth or the enzyme reaction solution containing sulfate ions to precipitate the sulfate ions as crystals of the resulting metal sulfate, (2) removing the metal sulfate crystals from the basic amino acid solution, (3) cooling the basic amino acid fermentation broth or the enzyme reaction solution from which the metal sulfate crystals have been removed while maintaining the concentration of the metal sulfate below its saturation concentration, resulting in precipitatation the basic amino acid as hydrochloride crystals, and (4) separating and collecting the basic amino acid hydrochloride crystals. | 11-26-2009 |
20090317876 | METHOD FOR PRODUCING AN L-AMINO ACID BY FERMENTATION USING A BACTERIUM HAVING AN ENHANCED ABILITY TO UTILIZE GLYCEROL - The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus | 12-24-2009 |
20090325242 | Alleles of the zwf gene from coryneform bacteria - The invention relates to mutants and alleles of the zwf gene of coryneform bacteria, which encode variants of the Zwf subunit of glucose 6-phosphate dehydrogenase (EC: 1.1.1.49), and to processes for preparing amino acids, in particular L-lysine and L-tryptophan, by using bacteria which harbor said alleles. | 12-31-2009 |
20100047878 | METHOD OF PRODUCING L-AMINO ACID - An L-amino acid is produced by culturing a microorganism belonging to the family Enterobacteriaceae having an L-amino acid-producing ability and modified so that glycerol dehydrogenase and dihydroxyacetone kinase activities are increased, in a medium containing glycerol as a carbon source to produce and accumulate an L-amino acid in the medium or cells, and collecting the L-amino acid from the medium or the cells. | 02-25-2010 |
20100055748 | L-AMINO ACID PRODUCING BACTERIUM AND METHOD FOR PRODUCING L-AMINO ACID - An L-amino acid can be produced by culturing an L-amino acid-producing bacterium which belongs to the Enterobacteriaceae family and which has been modified so that the expression of a yggG gene is enhanced. | 03-04-2010 |
20100062496 | L-AMINO ACID PRODUCING MICROORGANISM AND A METHOD FOR PRODUCING AN L-AMINO ACID - A microorganism belonging to the family | 03-11-2010 |
20100062497 | MICROORGANISM PRODUCING AN AMINO ACID OF THE L-GLUTAMIC ACID FAMILY AND A METHOD FOR PRODUCING THE AMINO ACID - A microorganism is cultured in a medium, and is able to produce one or two or more kinds of L-amino acids including L-glutamic acid, L-glutamine, L-proline, L-ornithine, L-citrulline and L-arginine, and is modified to increase α-ketoglutarate synthase activity. The L-amino acids are collected from the medium or the cells. | 03-11-2010 |
20100099152 | METHOD FOR PRODUCING L-AMINO ACID - L-amino acids such as L-glutamic acid, L-glutamine, L-proline, L-arginine, L-leucine, and L-cysteine are produced by culturing in a medium a bacterium having an L-amino acid-producing ability and wherein the bacterium has been modified so that the phosphotransacetylase activity is enhanced. | 04-22-2010 |
20100209977 | L-AMINO ACID-PRODUCING BACTERIUM AND A METHOD FOR PRODUCING AN L-AMINO ACID - A bacterium belonging to the family Enterobacteriaceae, which has an ability to produce an amino acid such as L-cysteine and has been modified to have specific mutation in the yeas gene, is cultured in a medium, and the L-amino acid is collected from the medium. | 08-19-2010 |
20100221792 | METHOD FOR PRODUCING AN L-AMINO ACID - An L-amino acid is produced by culturing a bacterium belonging to the family Enterobacteriaceae, which is able to produce the L-amino acid, and is modified so that the activity of ribonuclease G is decreased in a medium containing glycerol as the carbon source, and collecting the L-amino acid from the culture. | 09-02-2010 |
20100267094 | USE OF PHOSPHOKETOLASE FOR PRODUCING USEFUL METABOLITES - The present invention provides a bacterium which has an ability to produce a useful metabolite derived from acetyl-coenzyme A, such as L-glutamic acid, L-glutamine, L-proline, L-arginine, L-leucine, L-cysteine, succinate, and polyhydroxybutyrate, wherein said bacterium is modified so that activities of D-xylulose-5-phosphate phosphoketolase and/or fructose-6-phosphate phosphoketolase are enhanced. The present invention also provides a method for producing the useful metabolite using the bacterium. | 10-21-2010 |
20100273221 | METHOD FOR PRODUCING BASIC SUBSTANCE - A method for producing a basic substance by fermentation comprising culturing a microorganism having an ability to produce the basic substance in a liquid medium contained in a fermentation tank to produce and accumulate the basic substance in the medium, wherein amount of sulfate and/or chloride ions used as counter ions of the basic substance is reduced by adjusting total ammonia concentration in the medium to be within a specific concentration range during at least a part of the total period of culture process. | 10-28-2010 |
20100279362 | Method for Producing an L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family With Attenuated Expression of the ybiV Gene - The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus | 11-04-2010 |
20100297711 | PROCESS FOR THE SYNTHESIS OF FOSINOPRIL AND INTERMEDIATES THEREOF - Process for the preparation of intermediates useful in the synthesis of [1[S(R)],2α,4β]-4-cyclohexyl-1-[[[(2-methyl-1-oxypropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-L-proline, and the synthesis thereof, in particular as sodium salt. | 11-25-2010 |
20100330622 | BACTERIUM PRODUCING A PRODUCT OF A REACTION CATALYZED BY A PROTEIN HAVING 2-OXOGLUTARATE-DEPENDENT ENZYME ACTIVITY AND A METHOD FOR MANUFACTURING THE PRODUCT - A method for manufacturing a product of a reaction catalyzed by a protein having 2-oxoglutarate-dependent enzyme activity such as (2S,3R,4S)-4-hydroxy-L-isoleucine or a salt thereof using a bacterium transformed with a DNA fragment containing a gene coding for a protein having 2-oxoglutarate-dependent enzyme activity such as L-isoleucine dioxygenase activity; and wherein said bacterium has the ability to produce a product such as (2S,3R,4S)-4-hydroxy-L-isoleucine. | 12-30-2010 |
20100330623 | COMPOSITIONS AND METHODS FOR AMINO ACID BIOSYNTHESIS - The present invention relates generally to compositions and methods useful for, inter alia, production of commercial biologic products such as amino acids. More specifically, the present invention relates to genetically modified strains of microorganisms and the use thereof for the production of commercial products. The present invention also provides, inter alia, novel isolated DNA, nucleic acid, vectors and reduced genome bacteria. | 12-30-2010 |
20110053227 | PROCESS FOR PREPARING L-AMINO ACIDS USING IMPROVED STRAINS OF THE ENTEROBACTERIACEAE FAMILY - The invention relates to a process for preparing L-amino acids by fermenting recombinant microorganisms of the Enterobacteriaceae family, characterized in that
| 03-03-2011 |
20110091942 | PROCESS FOR PRODUCTION OF CIS-4-HYDROXY-L-PROLINE - Development of a method of economically and efficiently producing cis-4-hydroxy-L-proline. The present invention provides L-proline cis-4-hydroxylase. This enzyme may be derived from | 04-21-2011 |
20110177566 | METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY - A method for producing an L-amino acid is described using a bacterium of the Enterobacteriaceae family, wherein the bacterium contains a protein which is able to confer resistance to growth inhibition by L-cysteine. | 07-21-2011 |
20110212496 | L-AMINO ACID-PRODUCING MICROORGANISM AND A METHOD FOR PRODUCING AN L-AMINO ACID - An L-amino acid is produced by culturing a bacterium belonging to the family Enterobacteriaceae, which has an L-amino acid-producing ability and inherently has a native activity of a glucose dehydrogenase that uses pyrroloquinoline quinone as a coenzyme, but has been modified so that the activity of the glucose dehydrogenase is reduced, in a medium, and collecting the L-amino acid from the medium. | 09-01-2011 |
20110312042 | METHOD FOR PRODUCING AMINO ACID - According to the present invention, a process for producing an amino acid using a microorganism in which aspartate aminotransferase activity is decreased or deleted, and which has the capability of producing and accumulating the amino acid is provided. | 12-22-2011 |
20110318791 | MUTANT OF THE PROB GENE FROM CORYNEFORM BACTERIA - The invention relates to processes for fermentative production of L-proline using bacteria which contain mutated variants of the proB gene. | 12-29-2011 |
20120190079 | METHOD FOR RACEMIZATION OF OPTICALLY ACTIVE ALPHA -AMINO ACIDS - The present invention relates to a method for racemizing an optically active α-amino acid with a viable bacterial cell producing γ-aminobutyric acid aminotransferase or a processed product thereof. According to the present invention, racemic α-amino acids of high quality can be manufactured inexpensively. | 07-26-2012 |
20120237985 | METHOD FOR PRODUCING L-AMINO ACID - A method for producing an L-amino acid by culturing a coryneform bacterium having an L-amino acid-producing ability in a medium to produce and accumulate the L-amino acid in the medium or cells of the bacterium, and collecting the L-amino acid from the medium or cells, wherein said coryneform bacterium has been modified to enhance carbonic anhydrase activity. | 09-20-2012 |
20120252075 | Microorganism and Method for the Fermentative Production of an Organic-Chemical Compound - The invention relates to a microorganism which produces and/or secretes an organic-chemical compound, wherein the microorganism has increased expression, compared to the particular starting strain, of one or more protein subunits of the ABC transporter having the activity of a trehalose importer, said microorganism being capable of taking up trehalose from the medium; and to a method for the production of an organic-chemical compound, using the microorganism according to the invention, wherein accumulation of trehalose in the fermentation broth is reduced or avoided. | 10-04-2012 |
20130004999 | VARIANTS OF THE PROMOTER OF THE GAP GENE CODING FOR GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE - The invention relates to an isolated polynucleotide having promoter activity, a variant of the promoter of the gap gene coding for glyceraldehyde-3-phosphate dehydrogenase; and to a microorganism which produces and/or secretes a fine chemical, the microorganism including the isolated polynucleotide having promoter activity, which enables various genes to be overexpressed in comparison with the particular starting strain; and to a process for preparing fine chemicals using the microorganism. | 01-03-2013 |
20130109063 | Method for Producing an L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family | 05-02-2013 |
20130157321 | Use of Phosphoketolase for Producing Useful Metabolites - The present invention provides a bacterium which has an ability to produce a useful metabolite derived from acetyl-coenzyme A, such as L-glutamic acid, L-glutamine, L-proline, L-arginine, L-leucine, L-cysteine, succinate, and polyhydroxybutyrate, wherein said bacterium is modified so that activities of D-xylulose-5-phosphate phosphoketolase and/or fructose-6-phosphate phosphoketolase are enhanced. The present invention also provides a method for producing the useful metabolite using the bacterium. | 06-20-2013 |
20130224806 | Method for Producing an L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family - A method for producing an L-amino acid is described using a bacterium of the Enterobacteriaceae family, wherein the bacterium contains a protein which is able to confer resistance to growth inhibition by L-cysteine. | 08-29-2013 |
20130288313 | Method of Producing L-Amino Acid - An L-amino acid is produced by culturing a microorganism belonging to the family Enterobacteriaceae having an L-amino acid-producing ability and modified so that glycerol dehydrogenase and dihydroxyacetone kinase activities are increased, in a medium containing glycerol as a carbon source to produce and accumulate an L-amino acid in the medium or cells, and collecting the L-amino acid from the medium or the cells. | 10-31-2013 |
20130295621 | Method for Producing a Target Substance by Fermentation - A target substance can be produced by culturing a bacterium having an ability to produce 2-ketoglutaric acid or a derivative thereof, and an ability to produce xylonic acid from xylose, which is imparted with xylonate dehydratase activity, 2-keto-3-deoxyxylonate dehydratase activity and 2-ketoglutaric semialdehyde dehydrogenase activity, or in which these activities are enhanced, in a medium containing xylose as a carbon source to produce and accumulate the target substance in the medium, and collecting the target substance from the medium. | 11-07-2013 |
20130330786 | PROCESS FOR PRODUCTION OF CIS-4-HYDROXY-L-PROLINE - Development of a method of economically and efficiently producing cis-4-hydroxy-L-proline. The present invention provides L-proline cis-4-hydroxylase. This enzyme may be derived from | 12-12-2013 |
20130330787 | METHOD FOR PRODUCING CHEMICAL BY CONTINUOUS FERMENTATION - A method produces a chemical through continuous fermentation including: (a) culturing a cell in a culture medium in a fermentor to ferment a feedstock to produce a chemical; (b) conducting filtration of the culture medium with a separation membrane module; (c) separating a permeate containing the chemical from the culture medium while retaining a non-permeated liquid in the fermentor, and (d) supplying a gas from at least one of a lower portion of the separation membrane module and a pipe communicating between the fermentor and the separation membrane module to adjust a gas linear velocity in the separation membrane module to 0.15 cm/s to 70 cm/s while supplying the separation membrane module with a liquid. | 12-12-2013 |
20140051132 | Method for Producing an L-Amino Acid Belonging to the Glutamate Family, Using a Coryneform Bacterium - The present invention provides a method for producing an L-amino acid belonging to the glutamate family, using a coryneform bacterium which has been modified so that expression of one or more gene(s) of the NCgl_2067-NCgl_2065 operon in said bacterium is/are attenuated. | 02-20-2014 |
20140127762 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALPHA-SUBSTITUTED PROLINE - The present invention aims to provide an industrial method practically suitable for producing optically active α-substituted prolines from an acyclic ketone compound by a small number of steps under mild conditions. The present invention relates to a production method of an optically active α-substituted proline (4) and/or an optically active α-substituted prolinamide (5), including (a) reacting an acyclic ketone compound (1) with at least one selected from ammonia, an ammonium salt, primary amine and a salt of primary amine, and a cyanating agent to give a cyclic nitrogen-containing compound (2), (b) hydrating the cyclic nitrogen-containing compound (2) to give an α-substituted prolinamide (3), and (c) resolving the α-substituted prolinamide (3) by one or more of (d) enzymatical hydrolysis, (e) resolution by diastereomeric salt formation, and (f) separation by column chromatography. | 05-08-2014 |
20140162325 | Method for Producing an L-Amino Acid Using a Bacterium of the Family Enterobacteriaceae Having Enhanced Expression of the Flagella Formation and Motility Cascade Genes - The present invention provides a method for producing L-amino acid using a bacterium belonging to the family Enterobacteriaceae, particularly a motile bacterium belonging to the genus | 06-12-2014 |
20140242643 | The Use of Phosphoketolase for Producing Useful Metabolites - The present invention provides a bacterium which has an ability to produce a useful metabolite derived from acetyl-coenzyme A, such as L-glutamic acid, L-glutamine, L-proline, L-arginine, L-leucine, L-cysteine, succinate, and polyhydroxybutyrate, wherein said bacterium is modified so that activities of D-xylulose-5-phosphate phosphoketolase and/or fructose-6-phosphate phosphoketolase are enhanced. The present invention also provides a method for producing the useful metabolite using the bacterium. | 08-28-2014 |
20140287472 | Method for Producing L-Amino Acids Using Bacteriua of the Enterobacteriaceae Family - There is disclosed a method for producing L-amino acid, for example L-threonine, L-lysine, L-histidine, L-phenylalanine, L-arginine or L-glutamic acid, using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance an activity of D-xylose permease. | 09-25-2014 |
20140315261 | METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE FAMILY ENTEROBACTERIACEAE HAVING ATTENUATED EXPRESSION OF THE yjjK GENE - The present invention provides a method for producing L-amino acids by fermentation using a bacterium of the family Enterobacteriaceae, particularly a bacterium belonging to the genus | 10-23-2014 |
20150010962 | Method for Producing Basic Substance - A method for producing a basic substance by fermentation comprising culturing a microorganism having an ability to produce the basic substance in a liquid medium contained in a fermentation tank to produce and accumulate the basic substance in the medium, wherein amount of sulfate and/or chloride ions used as counter ions of the basic substance is reduced by adjusting total ammonia concentration in the medium to be within a specific concentration range during at least a part of the total period of culture process. | 01-08-2015 |
20150010963 | Method for Producing Basic Substance - A method for producing a basic substance by fermentation comprising culturing a microorganism having an ability to produce the basic substance in a liquid medium contained in a fermentation tank to produce and accumulate the basic substance in the medium, wherein amount of sulfate and/or chloride ions used as counter ions of the basic substance is reduced by adjusting total ammonia concentration in the medium to be within a specific concentration range during at least a part of the total period of culture process. | 01-08-2015 |
20150056665 | METHOD OF PRODUCING CHEMICAL BY CONTINUOUS FERMENTATION AND CONTINUOUS FERMENTATION APPARATUS - A method of producing a chemical includes culturing cells in a culture solution in a fermentor to ferment a feedstock to produce a chemical; supplying the culture solution containing the chemical produced in the culturing to a plurality of separation membrane units arranged in parallel; filtering the culture solution supplied in the supplying to separate a permeate containing the chemical; refluxing a retentate that is not filtered in the filtering to the fermentor; and supplying a gas containing oxygen to the plurality of separation membrane units while a supply amount is changed to at least two different values to perform scrubbing, wherein the supply amount and supply time of the gas containing oxygen supplied in the culturing and the supplying the gas are set so that a kLa value is within a predetermined range from an optimal kLa value for the cells cultured in the culturing. | 02-26-2015 |
20150056666 | VARIANTS OF THE PROMOTER OF THE GAP GENE CODING FOR GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE - The invention relates to an isolated polynucleotide having promoter activity, a variant of the promoter of the gap gene coding for glyceraldehyde-3-phosphate dehydrogenase; and to a microorganism which produces and/or secretes a fine chemical, the microorganism including the isolated polynucleotide having promoter activity, which enables various genes to be overexpressed in comparison with the particular starting strain; and to a process for preparing fine chemicals using the microorganism. | 02-26-2015 |
20150118719 | BIOCATALYSTS AND METHODS FOR HYDROXYLATION OF CHEMICAL COMPOUNDS - The present disclosure provides engineered proline hydroxylase polypeptides for the production of hydroxylated compounds, polynucleotides encoding the engineered proline hydroxylases, host cells capable of expressing the engineered proline hydroxylases, and methods of using the engineered proline hydroxylases to prepare compounds useful in the production of active pharmaceutical agents. The present disclosure provides engineered proline hydroxylase biocatalysts, polynucleotides encoding the biocatalysts. methods of their preparation, and processes for preparing hydroxylated compounds using these engineered biocatalysts. | 04-30-2015 |
20150140614 | VARIANTS OF THE PROMOTER OF THE GAP GENE CODING FOR GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE - The invention relates to an isolated polynucleotide having promoter activity, a variant of the promoter of the gap gene coding for glyceraldehyde-3-phosphate dehydrogenase; and to a microorganism which produces and/or secretes a fine chemical, the microorganism including the isolated polynucleotide having promoter activity, which enables various genes to be overexpressed in comparison with the particular starting strain; and to a process for preparing fine chemicals using the microorganism. | 05-21-2015 |
20150337254 | APPARATUS FOR CONTROLLING AMMONIA AND A METHOD FOR CONTROLLING AMMONIA - An method for controlling ammonia concentration of a culture medium contained in a culture tank, by using an ammonia-controlling apparatus comprising at least an ammonia feeder that supplies ammonia to the culture tank, an ammonia sensor that responds to non-ionized ammonia in the culture medium contained in the culture tank, and a control part connected to the ammonia feeder and the ammonia sensor, and which method comprises the following steps performed by the control part: calculating non-ionized ammonia concentration of the culture medium contained in the culture tank from the signal from the ammonia sensor by using a calibration curve representing relation between non-ionized ammonia concentration of the culture medium contained in the culture tank and a signal from the ammonia sensor; and directing the ammonia feeder to supply ammonia to the culture tank when the calculated non-ionized ammonia concentration is lower than a predetermined concentration. | 11-26-2015 |
20150353974 | PROCESSING BIOMASS - Biomass (e.g., plant biomass, animal biomass, microbial, and municipal waste biomass) is processed to produce useful products, such as food products and amino acids. | 12-10-2015 |
20160053335 | MICROORGANISM AND METHOD FOR PRODUCTION OF AMINO ACIDS BY FERMENTATION - The invention relates to a microorganism that produces and/or secretes an organic chemical compound, wherein the microorganism has an increased expression, compared to the respective starting strain, of a polypeptide LpdA with the activity of a transhydrogenase; and a process for producing an organic chemical compound using the microorganism according to the invention. | 02-25-2016 |
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