| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 435047000 | Preparing compound having a 1-thia-5-aza-bicyclo (4.2.0) octane ring system (e.g., cephalosporin, etc.) | 20 |
| 20090325224 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE N-PROTECTED 3-AMINOPYRROLIDINE OR OPTICALLY ACTIVE N-PROTECTED 3-AMINOPIPERIDINE AND THE CORRESPONDING KETONES BY OPTICAL RESOLUTION OF THE RACEMIC AMINE MIXTURES EMPLOYING A BACTERIAL OMEGA-TRANSAMINASE - The present invention relates to the production of optically active amines, which can be used as intermediate products in a synthesis of for instance pharmaceutical products. | 12-31-2009 |
| 20100086965 | METABOLIC ENGINEERING OF ARABINOSE-FERMENTING YEAST CELLS - The invention relates to an eukaryotic cell expressing nucleotide sequences encoding the ara A, ara B and ara D enzymes whereby the expression of these nucleotide sequences confers on the cell the ability to use L-arabinose and/or convert L-arabinose into L-ribulose, and/or xylulose 5-phosphate and/or into a desired fermentation product such as ethanol. Optionally, the eukaryotic cell is also able to convert xylose into ethanol. | 04-08-2010 |
| 20100112633 | Two-Step Enzyme Method for Preparing 7-Aminocephalosporanic Acid - The present invention discloses a two-step enzyme method for preparing 7-aminocephalosporanic acid from cephalosporin C, wherein D-amino acid oxidase used is purified D-amino acid oxidase mutant of yeast | 05-06-2010 |
| 20110189728 | PENTOSE SUGAR FERMENTING CELL - The invention relates to a cell which comprises a nucleotide sequence encoding a xylose isomerase, wherein the amino acid sequence of the xylose isomerase has at least about 70% sequence identity to the amino acid sequence set out in SEQ ID NO: 3 and wherein the nucleotide sequence is heterologous to the host. A cell of the invention may be used in a process for producing a fermentation product, such as ethanol. Such a process may comprise fermenting a medium containing a source of xylose with a cell of the invention such that the cell ferments xylose to the fermentation product. | 08-04-2011 |
| 20110269180 | Prokaryotic Xylose Isomerase for the Construction of Xylose Fermenting Yeasts - The present invention relates to the use of nucleic acid molecules coding for a bacterial xylose isomerase (XI), preferably coming from | 11-03-2011 |
| 20120183993 | PROCESS FOR ENZYMATIC HYDROLYSIS OF LIGNOCELLULOSIC MATERILA AND FERMENTATION OF SUGARS - The invention relates to a process for the preparation of a fermentation product from ligno-cellulosic material, comprising the following steps: | 07-19-2012 |
| 20120208231 | METABOLIC ENGINEERING OF ARABINOSE-FERMENTING YEAST CELLS - The invention relates to an eukaryotic cell expressing nucleotide sequences encoding the ara A, ara B and ara D enzymes whereby the expression of these nucleotide sequences confers on the cell the ability to use L-arabinose and/or convert L-arabinose into L-ribulose, and/or xylulose 5-phosphate and/or into a desired fermentation product such as ethanol. Optionally, the eukaryotic cell is also able to convert xylose into ethanol. | 08-16-2012 |
| 20120225451 | METABOLIC ENGINEERING OF XYLOSE-FERMENTING EUKARYOTIC CELLS - The present invention relates to genetic modifications in eukaryotic host cells that have been transformed to express a xylose isomerase that confers on the host cell the ability to isomerize xylose to xylulose. These genetic modifications are aimed at improving the efficiency of xylose metabolism and include. e.g., reduction of nonspecific aldose reductase activity, increased xylulose kinase activity and increased flux of the pentose phosphate pathway. The modified host cells of the invention are suitable for the production of a wide variety of fermentation products, including ethanol, in fermentation processes in which a source of xylose or a source of xylose and glucose are used as carbon source. | 09-06-2012 |
| 20120225452 | NUCLEIC ACID MOLECULE FOR ENCODING XYLOSE ISOMERASE AND XYLOSE ISOMERASE ENCODED BY THE NUCLEIC ACID MOLECULE - A novel xylose isomerase nucleotide sequence obtained from a bovine rumen fluid metagenomic library and also provides the amino acid sequence encoded by the nucleotide sequence, and a vector and a transformant containing the nucleotide sequence. When the xylose isomerase is expressed, a host cell is endowed with the capability of converting xylose into xylulose, and the xylulose is further metabolized by the host cell. Therefore, the host cell can take the xylose as a carbon source for growth. The xylose isomerase from a new source is expressed with high activity in | 09-06-2012 |
| 20130059331 | CELL SUITABLE FOR FERMENTATION OF A MIXED SUGAR COMPOSITION - The present invention relates to a cell suitable for production of one or more fermentation product from a sugar composition comprising glucose, galactose, arabinose and xylose, wherein the cell comprises two to fifteen copies of one or more xylose isomerase gene or two to fifteen copies of one or more xylose reductase and xylitol dehydrogenase, and two to ten copies of araA, araB and araD, genes, wherein these genes are integrated into the cell genome. | 03-07-2013 |
| 20140134672 | BIOREACTORS CIRCULATION APPARATUS, SYSTEM AND METHOD - Bioreactors, and particularly, photobioreactors having a reactor chamber and surge driver, and methods for using these devices, for example, for the production of carbon-based products are provided. The reactor chamber provides a housing for microorganisms and culture medium. The surge driver produces a surge of the microorganisms and/or culture medium in the reactor chamber. | 05-15-2014 |
| 20140162312 | PENTOSE SUGAR FERMENTING CELL - The invention relates to a cell which comprises a nucleotide sequence encoding a xylose isomerase, wherein the amino acid sequence of the xylose isomerase has at least 75% sequence identity to the amino acid sequence set out in SEQ ID NO: 2 and wherein the nucleotide sequence is heterologous to the host. A cell of the invention may be used in a process for producing a fermentation product, such as ethanol. Such a process may comprise fermenting a medium containing a source of xylose with a cell of the invention such that the cell ferments xylose to the fermentation product. | 06-12-2014 |
| 20140186884 | Xylose Isomerases and Their Uses - This disclosure relates to novel xylose isomerases and their uses, particularly in fermentation processes that employ xylose-containing media. | 07-03-2014 |
| 20150010943 | METABOLIC ENGINEERING OF XYLOSE-FERMENTING EUKARYOTIC CELLS - The present invention relates to genetic modifications in eukaryotic host cells that have been transformed to express a xylose isomerase that confers on the host cell the ability to isomerize xylose to xylulose. These genetic modifications are aimed at improving the efficiency of xylose metabolism and include, e.g., reduction of nonspecific aldose reductase activity, increased xylulose kinase activity and increased flux of the pentose phosphate pathway. The modified host cells of the invention are suitable for the production of a wide variety of fermentation products, including ethanol, in fermentation processes in which a source of xylose or a source of xylose and glucose are used as carbon source. | 01-08-2015 |
| 20150017683 | Stacked Membrane Bioreactor - Scalable biomaterial-based bioreactors are described. In one embodiment, the bioreactor may comprise perforated plates stacked such that the assembled bioreactor has the necessary manifolds and chambers to transport gas and liquids to a biomaterial contained within the bioreactor, and to remove the reaction products. In another embodiment, single use bioreactors are described. Methods of operating the bioreactors are also described. | 01-15-2015 |
| 20150031076 | TRANSFORMED CELLS THAT FERMENT PENTOSE SUGARS AND METHODS OF THEIR USE - The present invention relates to host cells transformed with a nucleic acid sequence encoding a eukaryotic xylose isomerase obtainable from an anaerobic fungus. When expressed, the sequence encoding the xylose isomerase confers to the host cell the ability to convert xylose to xylulose which may be further metabolized by the host cell. Thus, the host cell is capable of growth on xylose as carbon source. The host cell preferably is a eukaryotic microorganism such as a yeast or a filamentous fungus. The invention further relates to processes for the production of fermentation products such as ethanol, in which a host cell of the invention uses xylose for growth and for the production of the fermentation product. The invention further relates to nucleic acid sequences encoding eukaryotic xylose isomerases and xylulose kinases as obtainable from anaerobic fungi. | 01-29-2015 |
| 20150099276 | PROKARYOTIC XYLOSE ISOMERASE FOR THE CONSTRUCTION OF XYLOSE-FERMENTING YEASTS - The present invention relates to the use of nucleic acid molecules coding for a bacterial xylose isomerase (XI), preferably coming from | 04-09-2015 |
| 20150291983 | CELL SUITABLE FOR FERMENTATION OF A MIXED SUGAR COMPOSITION - The present invention relates to a cell suitable for production of one or more fermentation product from a sugar composition comprising glucose, galactose, arabinose and xylose, wherein the cell comprises two to fifteen copies of one or more xylose isomerase gene or two to fifteen copies of one or more xylose reductase and xylitol dehydrogenase, and two to ten copies of araA, araB and araD, genes, wherein these genes are integrated into the cell genome. | 10-15-2015 |
| 20150307903 | PROCESS FOR ENZYMATIC HYDROLYSIS OF LIGNOCELLULOSIC MATERIAL AND FERMENTATION OF SUGARS - The invention relates to a process for the preparation of a fermentation product from ligno-cellulosic material, comprising the following steps:
| 10-29-2015 |
| 20150337340 | PENTOSE FERMENTATION BY A RECOMBINANT MICROORGANISM - The present invention provides methods and compositions suitable for use in the isomerization of xylose to xylulose, as well as methods and compositions suitable for use in the conversion of xylose to xylitol and xylulose, including nucleic acid constructs, recombinant fungal host cells, and related materials. | 11-26-2015 |
