Class / Patent application number | Description | Number of patent applications / Date published |
424572000 | Tissue, other than lymphoid tissue (e.g., connective, etc.) | 71 |
20080213389 | Three-Dimensional Scaffolds for Tissue Engineering Made by Processing Complex Extracts of Natural Extracellular Matrices - Methods of making a biologically active three-dimensional scaffold capable of supporting growth and differentiation of a cell are described. Biologically active three-dimensional scaffold made by the methods of the invention and an engineered tissue made from the scaffolds are described. Fibers of desired porosity can be obtained from non-structural ECM by lyophilization and/or electrospinning which can be useful for numerous tissue engineering applications requiring complex scaffolds, such as wound healing, artificial skin (burns), soft tissue replacement/repair and spinal cord injury. | 09-04-2008 |
20090061014 | Synthetic peptide and peptide conjugates and related tissue coupling methods via transglutaminase enzyme - Peptides and conjugates thereof comprising one or more bioactive agents which can be coupled to a tissue via a transglutaminase and related methods. | 03-05-2009 |
20090186097 | Transgenic Ungulates Expressing CTLA4-IG and Uses Thereof - The present invention provides ungulates, including pigs, expressing CTLA4-Ig, as well as tissue, organs, cells and cell lines derived from such animals. Such animals, tissues, organs and cells can be used in research and medical therapy, including xenotransplanation. In addition, methods are provided to prepare organs, tissues and cells expressing the CTLA4-Ig for use in xenotransplantation, and nucleic acid constructs and vectors useful therein. | 07-23-2009 |
20090191278 | HOMEOPATHY-BASED FORMULATION - A formulation comprising a potentized mixture of triturated Lichen planus tissue with histamine in the ratio of about 1:2 to about 2:1 in a vehicle, where the ratio of the mixture to the vehicle, can be varied from 1:99 to 50:50. | 07-30-2009 |
20100028455 | NUTRITIONAL SUPPLEMENT - A nutritional supplement derived from skeletal tissue found in bony and cartilaginous fish has been found to be useful in the treatment of mineral deficiencies, in particular calcium deficiency, and additionally, in the treatment of arthritis, kidney stones, and gout in animals, including humans. A nutritional supplement composition and a pharmaceutical composition containing the nutritional supplement are also provided. The nutritional supplement contains 300,000 to 400,000 mg/kg calcium, 100 to 150 mg/kg phosphorous, 10 to 20 mg/kg magnesium, and 1,500 to 2,000 mg/kg sodium. | 02-04-2010 |
20100104658 | GRAFT PROSTHESIS, MATERIALS AND METHODS - A graft prostheses ( | 04-29-2010 |
20100119615 | DRIED AND IRRADIATED SKIN EQUIVALENTS FOR READY USE - The present invention relates generally to systems and methods for preparing, storing, shipping and using skin equivalents made by organotypic culture. In particular, the present invention relates to systems and methods for producing, transporting, storing and using skin equivalents produced by organotypic culture at reduced temperatures, preferably from 2-8 degrees Celsius to ambient temperature. The methods include sterile packaging of the grafts so that the sterility and integrity of the package is maintained until the time of use for grafting purposes. | 05-13-2010 |
20100129463 | MULTI-FORMED COLLAGENOUS BIOMATERIAL MEDICAL DEVICE FOR USE IN WOUND CARE - The invention involves a submucosa tissue that has the capability of being shape formed or shape configured. The submucosa involves a purified form of submucosa tissue. Optionally, the submucosa can be packaged in such a manner to permit sterility or maintain sterility of the submucosa. | 05-27-2010 |
20110097421 | Method for the Cosmetic Treatment of Skin Ageing - The present invention relates to a method for the cosmetic prevention or treatment of skin ageing in an individual, comprising administering to said individual a cosmetically active quantity of a gingival fibroblast-derived product. | 04-28-2011 |
20110111051 | PROPHYLACTIC OR ALLEVIATING AGENT FOR PERIPHERAL NERVE DISORDER INDUCED BY ANTI-CANCER AGENT - There is provided a medicinal agent that is effective and highly safe for the prevention or alleviation of a peripheral nerve disorder that develops as a side effect occurring after the administration of an anti-cancer agent. The present invention relates to a novel medical use of an extract from inflamed tissues inoculated with vaccinia virus, and to a prophylactic or alleviating agent for a peripheral nerve disorder that contains the extract as an active ingredient. The agent containing the extract as an active ingredient is used for a prophylactic or alleviating agent for a peripheral nerve disorder induced by an anti-cancer agent and is a highly safe and remarkably highly useful medicinal agent with few side effects. | 05-12-2011 |
20110244054 | SCAFFOLD MATERIAL FOR WOUND CARE AND/OR OTHER TISSUE HEALING APPLICATIONS - A scaffold material for wound care and/or other tissue healing applications and methods for making the same is described. The scaffold material is constituted of a decellularized extracellular matrix from fish skin. The scaffold material may also include lipids from the lipid layer of the fish skin. Methods for making and using the scaffold material are also described. | 10-06-2011 |
20120040013 | Regenerative Tissue Scaffolds - Methods, mixtures, and kits related to treating tissue are provided. The methods, mixtures, and kits can include an acellular tissue matrix, a polymer, and a solvent and may be capable of producing tissue scaffolds. The tissue scaffolds may be able to form a stable, three-dimensional shape in situ and elicit a limited immunologic or inflammatory response. | 02-16-2012 |
20120219634 | TOPICAL DERMAL FORMULATIONS - An autologous topical formulation containing conditioned medium obtained from culture of autologous fibroblasts has been developed. Unlike other topical formulations, it is autologous since it is derived solely from cells obtained by the person who is to use the formulation. This avoids any possible reaction with proteins derived from the cells. Preferred formulations include gels, creams, lotions, and ointments. The topical formulations of conditioned medium obtained by culturing autologous dermal fibroblasts are topically administered to individuals for the prevention and treatment of scarring, reduction in signs of aging, and improvement in quality of skin. | 08-30-2012 |
20120225130 | COMPOSITIONS, METHODS, AND DEVICES FOR TREATING LIVER DISEASE - Described are compositions and methods for treating liver disease, e.g., acute liver disease, using bone marrow-derived stem cells and bone marrow-derived stem cell conditioned media. | 09-06-2012 |
20120237610 | INJECTABLE COMPOSITIONS FOR INTRA-ARTICULAR USE COMBINING A VISCOSUPPLEMENTATION AGENT AND A FIBROBLAST GROWTH MEDIUM - Provided is an injectable composition for intra-articular administration including at least one viscosupplementation agent selected from hyaluronic acid, chondroitin sulphate, keratin, keratin sulphate, heparin, cellulose and derivatives thereof, for example, chitosan, xanthans, galactomannan, alginates, and one or more salts thereof, and a fibroblast growth medium. The viscosupplementation agent and the fibroblast growth medium can be provided in a single composition for injection or as separate components for simultaneous, separate, or subsequent injection over time. | 09-20-2012 |
20120276213 | METHOD FOR ENZYMATIC TREATMENT OF TISSUE PRODUCTS - Methods for treating tissue matrices and tissue matrices produced according to the methods are provided. The methods can include treating a tissue matrix with a proteolytic enzyme to produce a desired pliability of the tissue matrix. | 11-01-2012 |
20120294953 | Surface Modified Biological Materials - Disclosed in certain embodiments is a composition comprising a biological material and transition metal atoms selected from the group consisting of Group IVB, Group VB, Group VIB of the Periodic Chart and a combination thereof, bound to a surface of the biological material. | 11-22-2012 |
20130095191 | Passive Methods for Anti-Microbial Biologic Meshes - Tissue matrices having anti-microbial properties are provided. In certain embodiments, the tissue matrices include cationic anti-microbial agents that form a stable bond with the tissue matrices without adversely affecting the biologic properties of the tissue matrices. | 04-18-2013 |
20130183386 | PROCESS FOR OBTAINING A RABBIT SKIN COMPRISING BIOLOGICAL ACTIVE SUBSTANCES - The present invention relates to a process for obtaining a rabbit skin containing biologically active substances. The rabbit skin extract is obtained by the process including vaccinating a rabbit subcutaneously with vaccinia virus, feeding the rabbit, killing the rabbit when the skin is inflamed, skinning the rabbit within 15 minutes of death, preserving the rabbit skin at −18 degrees Celsius, extracting a portion of the rabbit skin with a phenol solution at 4° C., processing the rabbit skin extract with an acid and an alkali, eluting the rabbit skin extract and fractioning under a nitrogen atmosphere the eluted portion of the rabbit skin extract. The rabbit skin of the present invention can be used for preparing drugs and health foods. | 07-18-2013 |
20130195991 | Composition for Treatment of Damaged Part - The present invention provides a damaged part treatment composition for repairing a damaged part of a target tissue that includes a stem cell-conditioned medium obtained by culturing stem cells; a damaged part treatment method for repairing or restoring a damaged part of a target tissue that includes administering the damaged part treatment composition to a patient having the target tissue for the damaged part treatment composition in an amount therapeutically effective for repairing the damaged part of the target tissue; a method of treating cerebral infarction that includes administering the damaged part treatment composition to a cerebral infarct patient in an amount effective for repairing a damaged part of the brain; and a method of treating a CNS disease that includes administering, as a CNS disease treatment composition, the damaged part treatment composition to a CNS disease patient in a therapeutically effective amount. | 08-01-2013 |
20130209572 | XENOGRAFT SOFT TISSUE IMPLANTS AND METHODS OF MAKING - The present application is directed to the field of implants comprising soft tissue for use in implantation in humans. The soft tissue implants of the present application are preferably obtained from xenograft sources. The present application provides a chemical process that sterilizes, removes antigens from and/or strengthens xenograft implants. The present techniques yield soft tissue implants having superior structural, mechanical, and/or biochemical integrity. The present application is also directed to processes for treating xenograft implants comprising soft tissues such as dermis, and to implants produced by such processes. | 08-15-2013 |
20130230601 | ISOLATED MESENCHYMAL PROGENITOR CELLS AND EXTRACELLULAR MATRIX PRODUCED THEREBY - Provided are methods of isolating an extracellular matrix from mesenchymal progenitor cells which are characterized by a reduced differentiation ability into an adipogenic lineage as compared to adipose-derived mesenchymal stem cells. Also provide isolated extracellular matrix and hybrid devices comprising electrospun elements and extracellular matrix which can be used for various tissue regeneration, repair and reconstruction surgeries. | 09-05-2013 |
20130316013 | Compositions for Preventing Cardiac Arrhythmia - Disclosed herein are compositions and methods for treating or preventing a cardiac arrhythmia in a subject. | 11-28-2013 |
20130344161 | Conditioned Medium and Extracellular Matrix Compositions from Cells Cultured under Hypoxic Conditions - The present invention is directed to a method of producing compositions including embryonic proteins. The method includes culturing cells under hypoxic conditions on a biocompatible surface in vitro. The culturing method produces both soluble and non-soluble fractions, which may be used separately or in combination to obtain physiologically acceptable compositions useful in a variety of medical and therapeutic applications. | 12-26-2013 |
20140099383 | Topical Dermal Formulations - An autologous topical formulation containing conditioned medium obtained from culture of autologous fibroblasts has been developed. Unlike other topical formulations, it is autologous since it is derived solely from cells obtained by the person who is to use the formulation. This avoids any possible reaction with proteins derived from the cells. Preferred formulations include gels, creams, lotions, and ointments. The topical formulations of conditioned medium obtained by culturing autologous dermal fibroblasts are topically administered to individuals for the prevention and treatment of scarring, reduction in signs of aging, and improvement in quality of skin. | 04-10-2014 |
20140193515 | COLLOIDAL COLLAGEN BURN WOUND DRESSING PRODUCED FROM JELLYFISH - The present invention relates to methods of forming wound dressings from jellyfish collagen. A jellyfish tissue is provided, after which an acid is added to produce a collagen-salt solution. The solution is mixed to form a viscous colloidal gel, and a film or a film/fabric composite is created from the gel. | 07-10-2014 |
20140314872 | Methods of Use of Culture Supernatant Obtained from Mesenchymal Stem Cells from Dogs and Cats for Treatment of Organ Dysfunction - A method of treatment of organ dysfunction using a supernatant containing molecules, cytokines and vesicles secreted from mesenchymal stem cells (MSC) from animals is provided. The MSC are cultured, and then centrifuged to separate them from the desired supernatant containing the molecules and vesicles that may be used for treatment. Treatment may be for dogs, cats, and similar animals. This treatment may be for any number of ailments including, but not limited to mitigation or reversal of complications from heart, kidney, liver, or other organ impairment. | 10-23-2014 |
20140342014 | METHODS OF STERILIZING FETAL SUPPORT TISSUES - Disclosed herein, are methods of preparing sterilized amniotic tissues. Further disclosed herein, are methods of using the sterilized amniotic tissues. | 11-20-2014 |
20140370116 | Method and System for Treatment of Biological Tissue - A composition for reconstruction, replacement or repair of damaged or diseased biological tissue comprising an extracellular matrix (ECM) composition that includes an ECM scaffold component and a bioactive agent component. In a preferred embodiment, the ECM scaffold component comprises mesothelial tissue and the bioactive agent comprises a statin. | 12-18-2014 |
20150037434 | BIOMATERIALS DERIVED FROM TISSUE EXTRACELLULAR MATRIX - Region-specific extracellular matrix (ECM) biomaterials are provided. Such materials include acellular scaffolds, sponges, solutions, and hydrogels suitable for stem cell culture. | 02-05-2015 |
20150335771 | METHODS OF STERILIZING FETAL SUPPORT TISSUES - Disclosed herein, are methods of preparing sterilized amniotic tissues. Further disclosed herein, are methods of using the sterilized amniotic tissues. | 11-26-2015 |
20160082153 | Method and System for Treatment of Damaged Biological Tissue - Biomaterial compositions and articles comprising mesothelial tissue and a glycosaminoglycan (GAG), for treating damaged biological tissue; particularly, damaged cardiovascular tissue. The biomaterial compositions and articles can also include additional biologically active agents, such as growth factors. The biomaterial compositions and articles induce modulated healing, including modulation of inflammation and induced neovascularization when administered to damaged biological tissue. | 03-24-2016 |
20160089402 | EXTRACT, AND PREPARATION CONTAINING SAID EXTRACT - An object of the present invention is to provide an extract from inflamed skins of rabbits inoculated with vaccinia virus where the quality of the extract is more stabilized and also to provide a preparation, etc. containing said extract as an active ingredient. | 03-31-2016 |
20160158290 | METHOD FOR TREATING CANCER - The present invention relates to a method for preventing or treating cancer in an individual comprising administering the individual with a prophylactically or therapeutically effective quantity of a gingival fibroblast-derived product. | 06-09-2016 |
20180021385 | WOUND HEALING FORMULATION | 01-25-2018 |
424574000 | Adipose or epithelium | 36 |
20080220085 | PRODUCTION OF NEURAL PROTECTIVE AND REGENERATIVE FACTORS FROM STEM CELLS AND TREATMENT OF NERVOUS SYSTEM CONDITIONS THEREWITH - A method for producing stem cell conditioned media for treatment of neurological insults is provided herein. By providing for the culture of adipose stem cells, and collecting the supernatants thereof, the supernatants have been shown to effect biological activity in preventing neural death when the supernatants are administered to a patient that has or is about to be subjected to a neural insult. | 09-11-2008 |
20090169642 | RECONSTRUCTED LIVING ADIPOSE TISSUE - The present invention relates to tissues and tissue sheets assembled from adipose-derived stromal cells. Particularly, it relates to reconstructed adipose tissues which comprise adipocytes as well as reconstructed conjunctive tissues which comprise adipose-derived stromal cells. The reconstructed tissues and sheets can be used, for example, in cosmetic applications for the replacement or addition of soft tissues, in pharmacological and toxicological applications for the in vitro testing of small molecules or cosmetic products as well as in therapeutic applications for the delivery of agents. | 07-02-2009 |
20090181104 | BREAST RECONSTRUCTION OR AUGMENTATION USING COMPUTER-MODELED DEPOSITION OF PROCESSED ADIPOSE TISSUE - A tissue transfer method for reconstruction and augmentation of soft tissue. The method includes harvesting adipose tissue from a patient. The harvested tissue is processed via centrifugation to isolate a purified subset of the adipose tissue including separating and removing a substantial amount of triglycerides from the harvested adipose tissue. The centrifugation may be performed to cause separation of water from the purified adipose tissue and to cause separation of oil from mature adipocytes. Specifically, the spin rates may be selected to be high enough to cause lesions in the mature adipocytes that results in the release of the oil. The method continues with implanting the purified adipose tissue into the patient at a breast or other area identified for reconstruction or augmentation. The implanting is performed based on an injection pathway model that defines injection point locations and a number of injection pathway directions from each point. | 07-16-2009 |
20090202654 | Skin Care Compositions and Treatments - The invention is directed compositions containing growth agents synthesized from cultured cells from skin. Skin cells such as keratinocytes and dermal fibroblasts are cultured in vitro in cell medium and in the course of culture the cultured cells synthesize and secrete agents into the cell medium. The medium containing agents are collected and incorporated into pharmaceutical or cosmetic preparations to treat an individual. The preparation is applied and has a rejuvenating effect on the cells and tissue. | 08-13-2009 |
20100112084 | METHOD AND APPARATUS FOR INCREASING ADIPOSE VASCULAR FRACTION - A method and device for processing mammalian adipose tissue such that the vascular rich fraction is separated from the vascular poor fraction, Mammalian adipose tissue in the form of morselated surgical biopsies and/or lipoaspirate from liposuction is placed within a novel syringe attached to a detection device measuring either color, light saturation, infra-red light, heme, iron or oxygen saturation. This process involves no label and minimal manipulation and handling of the tissue. This process and device may also be used intra-operatively under sterile conditions for immediate use within the same individual receiving liposuction or surgery. | 05-06-2010 |
20110003009 | PROCESS FOR OBTAINING A RABBIT SKIN COMPRISING BIOLOGICAL ACTIVE SUBSTANCES - The present invention relates to a process for obtaining a rabbit skin containing biologically active substances. The rabbit skin extract is obtained by the process including vaccinating a rabbit subcutaneously with vaccinia virus, feeding the rabbit, killing the rabbit when the skin is inflamed, skinning the rabbit within 15 minutes of death, preserving the rabbit skin at −18 degrees Celsius, extracting a portion of the rabbit skin with a phenol solution at 4° C., processing the rabbit skin extract with an acid and an alkali, eluting the rabbit skin extract and fractioning under a nitrogen atmosphere the eluted portion of the rabbit skin extract. The rabbit skin of the present invention can be used for preparing drugs and health foods. | 01-06-2011 |
20110183001 | COMPOSITIONS AND METHODS FOR IMPLANTATION OF ADIPOSE TISSUE AND ADIPOSE TISSUE PRODUCTS - The invention provides compositions and methods for the preparation of biocompatible biomaterials from adipose tissue. Biocompatible biomaterials are cellular or acellular biomaterials. The invention further provides methods of use of the biocompatible biomaterials. | 07-28-2011 |
20110217387 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF FIBROMYALGIA - A pharmaceutical composition for the treatment of fibromyalgia, which includes pilocarpine or a pharmacologically acceptable salt thereof. The pharmaceutical composition can be used as a novel therapeutic agent for fibromyalgia. | 09-08-2011 |
20110268814 | USE OF EXTRACTS FROM RABBIT SKIN INFLAMED BY VACCINIA VIRUS FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF ACUTE CEREBROVASCULAR DISEASE - The present invention provides a method for treatment of acute cerebrovascular diseases, and also provides the use of the extracts from rabbit skin inflamed by vaccinia virus in the manufacture of a medicament for treatment of acute cerebrovascular diseases. | 11-03-2011 |
20120135083 | DRIED PRODUCT AND A PROCESS FOR MANUFACTURING THE PRODUCT - A dried product of an extract from inflammatory rabbit skin inoculated with vaccinia virus having an inhibitory activity for the production of a kallikrein-like substance is produced by admixing the extract with a saccharide, sugar alcohol or ascorbic acid before reaching dryness, and then drying the admixture to a solid form such as granules. The dried product may be employed to produce a solid preparation for oral administration, such as tablets, having an inhibitory activity for the production of a kallikrein-like substance. | 05-31-2012 |
20120189707 | Production Method For Cryopreserved Acellular Dermal Matrix, And Cryopreserved Acellular Dermal Matrix Produced Thereby - The present invention relates to a production method for cryopreserved acellular dermal matrix and to cryopreserved acellular dermal matrix produced thereby, and more specifically it relates to a method in which a cryopreservation agent is made by adding sucrose to basic components consisting of glycerol and a basic solution and in which the resulting solution is used in the cryopreservation of skin tissue from which the cells in the epidermis and dermis have been removed, and relates to cryopreserved acellular dermal matrix produced thereby. | 07-26-2012 |
20120189708 | COMPOSITIONS AND IMPROVED SOFT TISSUE REPLACEMENT METHODS - The specification discloses compositions and methods for treating a soft tissue defect of an individual. | 07-26-2012 |
20120225131 | Methods For Treating Type Diabetes With Brown Adipose Transplants - The present invention provides for methods of treating diabetes by providing to a subject brown adipose tissue. The tissue may be transplanted from a culture of the subject's own tissue (autograft) or from a donor. These methods can achieve normoglycemia and suppress hypergluconemia, and alleviate conditions associated with such, even in the absence of or at extremely low levels of adjunct insulin therapy, and without any appreciable increase in insulinogenesis. | 09-06-2012 |
20130122109 | Chinese Medicine Hair-regrowth Preparation and Formula and Preparation Method Therefor - Disclosed in the present invention are a formula and preparation method for a hair-regrowth preparation, the preparation containing extracts of fresh ginger, huangqi (Radix astragali), heshouwu (Polygonum multiflorum), black ants, danggui ( | 05-16-2013 |
20130129835 | CROSSLINKED HYALURONIC ACID-COLLAGEN GELS FOR IMPROVING TISSUE GRAFT VIABILITY AND SOFT TISSUE AUGMENTATION - Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component. | 05-23-2013 |
20130164383 | METHOD FOR PROMOTING THE SYNTHESIS OF COLLAGEN AND PROTEOGLYCAN IN CHONDROCYTES - The synthesis of collagen and proteoglycan in chondrocytes, such as intervertebral disc cells, articular chondrocytes and meniscal cells is promoted by administration of an extract from inflamed tissue inoculated with vaccinia virus. | 06-27-2013 |
20130302436 | XENOGRAFT SOFT TISSUE IMPLANTS AND METHODS OF MAKING - The present application is directed to the field of implants comprising soft tissue for use in implantation in humans. The soft tissue implants of the present application are preferably obtained from xenograft sources. The present application provides a chemical process that sterilizes, removes antigens from and/or strengthens xenograft implants. The present techniques yield soft tissue implants having superior structural, mechanical, and/or biochemical integrity. The present application is also directed to processes for treating xenograft implants comprising soft tissues such as dermis, and to implants produced by such processes. | 11-14-2013 |
20140004206 | METHODS AND RELATED COMPOSITIONS FOR REDUCTION OF FAT AND SKIN TIGHTENING | 01-02-2014 |
20140072650 | GELATIN EXTRACT MADE FROM SKATE RAY SKIN AND ANTIHYPERTENSIVE COMPOSITION HAVING PEPTIDE ISOLATED FROM EXTRACT AS ACTIVE INGREDIENT - Disclosed is an antihypertensive composition containing as an active ingredient a gelatin extract made from the skins of a skate ray and a peptide isolated from the extract. The present invention is directed to a pharmaceutical composition for a hypertension prevention and therapy containing as an active ingredient a hydrolysate of a gelatin extract isolated from the skins of a skate ray, a method for preparing a hydrolysate of a gelatin extract made from the skins of a skate ray, and the use of a new peptide having an antihypertensive activity isolated and purified from the hydrolysate. | 03-13-2014 |
20140079802 | METHODS TO TREAT NERVOUS SYSTEM CONDITIONS - Methods to treat nervous system conditions. In at least one embodiment of a method of treating a mammalian patient having a neuronal injury or insult of the present disclosure, the method comprises the step of administering a therapeutically-effective dose of a stem cell conditioned medium to a mammalian patient, the stem cell conditioned medium comprising a cell culture supernatant containing at least one factor capable of exerting effective neuroprotection to treat a mammalian neural injury or insult. | 03-20-2014 |
20140087001 | Pharmaceutical Compositions and Topical Use Thereof - The present invention relates to methods for the preparation of compositions comprising adipose tissue-derived secretions, for example those derived from bovine adipose tissue, and the use of such compositions in the preparation of a pharmaceutical composition for topical use. The invention also relates to the use of adipose tissue-derived secretions and pharmaceutical compositions thereof for the topical treatment of a non-inflammatory condition, for example the treatment of a skin condition, and for the stimulation of hair growth in a subject by topical application. The invention also relates to the use of adipose tissue-derived secretions and pharmaceutical compositions thereof for the topical treatment of acne. | 03-27-2014 |
20140170233 | Natural feed mixture for breeding domesticated water birds - The invention relates to a natural feed mixture for breeding domesticated water birds, comprising a high carbohydrate containing basic component poor in methyl-donors, a component rich in carbohydrates, having hepatic insulin-sensitizing properties, hypothalamic appetite-stimulating plant parts, natural substances blocking cholesterol synthesis in the liver, and an additive for protecting the formation of non-cholesterol- mevalonate products. | 06-19-2014 |
20140170234 | COMPOSITIONS AND IMPROVED SOFT TISSUE REPLACEMENT METHODS - The present specification discloses compositions and methods of transplanting tissue, for example, in breast augmentation procedures. The compositions include adipose tissue and compounds that reduce tissue volume loss and increase survival rate of the adipose tissue when the composition is introduced into breast tissue. | 06-19-2014 |
20140255507 | METHOD FOR PROMOTING THE SYNTHESIS OF COLLAGEN AND PROTEOGLYCAN IN CHONDROCYTES - The synthesis of collagen and proteoglycan in chondrocytes, such as intervertebral disc cells, articular chondrocytes and meniscal cells is promoted by administration of an extract from inflamed tissue inoculated with vaccinia virus. | 09-11-2014 |
20150017254 | Method for Treatment of Cardiovascular Disorders - Methods for treating a cardiovascular disorder comprising concomitant administration of one or more extracellular matrix (ECM) based compositions directly to damaged or diseased cardiovascular tissue associated with the cardiovascular disorder, and provision of ventricular assistance. In a preferred embodiment, the ECM based compositions include an ECM material derived from a mammalian source. | 01-15-2015 |
20150037435 | CULTURE MEDIUM OF ADIPOSE-DERIVED STEM CELL, METHOD FOR PREPARING THE SAME, AND COMPOSITION INCLUDING THE SAME FOR PROMOTING HAIR GROWTH - Provided are a culture medium of an adipose-derived stem cell, a method for preparing the same, and a composition for promoting hair growth, in which the composition includes the culture medium. The adipose-derived stem cell (ADSC-T) according to the present invention exhibits long lifespan, improved cell proliferation rate, and extended proliferation period, as compared with a primary adipose-derived stem cell (ADSC), and thus, the adipose-derived stem cell (ADSC-T) can be usefully used for the study about the adipose-derived stem cell and the mass production of the culture medium of the adipose-derived stem cell. In addition, according to the present invention, the culture medium of the adipose-derived stem cell (ADSC-T) that expresses a T antigen of SV40 exhibits excellent hair growth effectiveness and can be usefully used as a raw material for the hair loss prevention and hair growing agents. | 02-05-2015 |
20150037436 | ACELLULAR SOFT TISSUE-DERIVED MATRICES AND METHODS FOR PREPARING SAME - An acellular soft tissue-derived matrix includes a collagenous tissue that has been delipidated and decellularized. Adipose tissue is among the soft tissues suitable for manufacturing an acellular soft tissue-derived matrix. Exogenous tissuegenic cells and other biologically-active factors may be added to the acellular matrix. The acellular matrix may be provided as particles, a slurry, a paste, a gel, or in some other form. The acellular matrix may be provided as a three-dimensional scaffold that has been reconstituted from particles of the three-dimensional tissue. The three-dimensional scaffold may have the shape of an anatomical feature and serve as a template for tissue repair or replacement. A method of making an acellular soft tissue-derived matrix includes steps of removing lipid from the soft tissue by solvent extraction and chemical decellularization of the soft tissue. | 02-05-2015 |
20150064273 | Mesenchymal Stem Cells Conditioned Medium and Methods of Generating and Using the Same - Mesenchymal stem cell conditioned medium and methods for preparing the conditioned medium are provided. The methods comprise culturing MSCs in a medium comprising nicotinamide or nicotinamide and fibroblast growth factor 4 (FGF4) and collecting the conditioned medium. Compositions comprising the mesenchymal stem cell conditioned medium and uses thereof are also provided. | 03-05-2015 |
20150147409 | ADIPOSE STROMAL VASCULAR FRACTION-CONDITIONED MEDIUM - A combination of therapeutic factors derived from non-adherent or poorly adherent stromal vascular fraction (SVF) cells exposed to protein-free basal medium are disclosed. | 05-28-2015 |
20150320816 | COMPOSITIONS FOR PROMOTION OF WOUND HEALING AND/OR SCAR REDUCTION - The present invention relates to a wound healing and scar reduction composition that is a unique product with key ingredients carefully selected to optimize scar reduction. The composition when used can help reduce the appearance of old and new scars. It is an ideal choice for use on all types of scar tissue including, new scars, old scars, surgical, keloids, hypertrophic, stretch marks and any skin condition that would benefit from barrier protection. | 11-12-2015 |
20160000970 | Crosslinked Soft Tissue Graft and Methods of Use Thereof - The invention relates to crosslinked soft tissue grafts and methods of use thereof. The invention also relates to methods of preparing the same. | 01-07-2016 |
20160045639 | Method for Enzymatic Treatment of Tissue Products - Methods for treating tissue matrices and tissue matrices produced according to the methods are provided. The methods can include treating a tissue matrix with a proteolytic enzyme to produce a desired pliability of the tissue matrix. | 02-18-2016 |
20160101200 | METHODS FOR STERILIZING COMPOSITIONS AND RESULTING COMPOSITIONS - Method for sterilizing a hydrogel composition include subjecting the composition to pulsed light comprising broadband spectrum radiation, the pulsed light being at a dose effective to sterilize the composition without causing significant change in rheology of the composition. | 04-14-2016 |
20160114080 | Elastase Treatment of Tissue Matrices - A method of producing a modified acellular tissue matrix (mATM) from an acellular tissue matrix (ATM), where the mATM has a reduced stretchiness relative to the ATM, without substantially compromising its associated structural or functional integrity. The method includes providing an acellular tissue matrix (ATM) and exposing the ATM to elastase for a period of time. | 04-28-2016 |
20160122713 | GENETICALLY-MODIFIED MICRO-ORGAN SECRETING A THERAPEUTIC PEPTIDE AND METHODS OF USE THEREOF - Provided herein is a genetically-modified micro-organ that provides a sustained delivery of a therapeutic peptide. The genetically-modified micro-organ may comprise a viral vector or expression cassette comprising at least two nucleic acid sequences encoding the therapeutic peptide separated by a cleavable linker. Further provided herein is a method of treating or preventing a disease or disorder in a human subject that can be treated or prevented by administration of a therapeutic peptide over a sustained time period using the genetically-modified micro-organ described herein. | 05-05-2016 |
20160199540 | METHOD FOR PREPARING AN ANIMAL DECELLULARIZED TISSUE MATRIX MATERIAL AND A DECELLULARIZED TISSUE MATRIX MATERIAL PREPARED THEREBY | 07-14-2016 |