| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 424550000 | Digestive system (e.g., salivary gland, etc.) | 32 |
| 20120301550 | METHOD FOR PRODUCING EXTRACTS FROM MATERIALS AND DEVICE FOR REALIZING SAME - The invention relates to a process and apparatus of extraction with the use of vacuum and can be used to extract the bioactive agents from raw materials. | 11-29-2012 |
| 20140017334 | HEAT-EXTRACTED OMENTUM EXTRACTS, COMPOSITIONS, METHODS OF PREPARING AND USES THEREOF - Disclosed herein are compositions including an extract of mammalian omentum wherein the extract is a liquid portion of the mammalian omentum, such as an oil, extracted when the omentum is heated to a temperature of between 210 and 240 degrees Fahrenheit. Also disclosed are methods of making a composition including an extract of mammalian omentum wherein the method includes heating mammalian omentum to a temperature of between 212 degrees Fahrenheit and 225 degrees Fahrenheit, such as 215 degrees Fahrenheit and 220 degrees Fahrenheit. Methods of use of the disclosed extracts and compositions are provided including methods of inducing or enhancing angiogenesis, methods of improving skin quality and methods of promoting hair growth and/or inhibiting hair loss. | 01-16-2014 |
| 424551000 | Gastrointestinal system (e.g., intestine, stomach, gall bladder, etc.) | 30 |
| 20080254138 | EXTRACELLULAR MATRIX TO RECRUIT STEM CELLS TO A SITE OF MALIGNANCY - The invention is to a method of recruiting stem cells to a site of malignancy by contacting the site with exogenous mammalian extracellular matrix in the form of a sheet article, or a composition comprising particulate extracellular matrix, or emulsion or gel extracellular matrix. | 10-16-2008 |
| 20090142409 | Extracellular Matrix Compositions for Tissue Regeneration - The invention is compositions of extracellular matrix that comprise mammalian extracellular matrix from two or more tissue sources in a mammal. The invention also includes methods of using these compositions to regenerate tissue or generate new tissue at sites of defects or wounds in mammals. | 06-04-2009 |
| 20120076869 | METHODS OF TREATING DEMENTIA USING OMENTUM - Dementia is treated by administering a composition that includes an omentum tissue or an aqueous or organic extract of the omentum tissue to a mammal in need of treatment of dementia. The composition can be administered to the mammal via oral administration, parenteral administration, inhalation, topical administration, rectal administration, vaginal administration, implantation, or any combinations thereof. The mammal can also be treated by stimulating a tissue that includes omentum. | 03-29-2012 |
| 20130122108 | Compositions for Regenerating Defective or Absent Myocardium - Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function. | 05-16-2013 |
| 20140161900 | Compositions for Regenerating Defective or Absent Myocardium - Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function. | 06-12-2014 |
| 20140328939 | METHOD FOR PREPARING BIOCOMPATIBLE SMALL INTESTINAL MUCOSA HYDROGEL CAPABLE OF CONTROLLING IN-VIVO DEGRADATION PERIOD - The present invention relates to a method for preparing a biocompatible small intestinal submucosa hydrogel with a controllable in-vivo degradation period, more particularly to a method for preparing a small intestinal submucosa hydrogel which is formed in a solution phase by forming chemical crosslinkages by solubilizing a biocompatible small intestinal submucosa powder and allows the degradation period of a gel formed during in-vivo injection by controlling the degree of crosslinking and a method for preparing a small intestine submucosa drug carrier or a small intestine submucosa support using the hydrogel. | 11-06-2014 |
| 20150099007 | Method and System for Treatment of Biological Tissue - A composition for reconstruction, replacement or repair of damaged or diseased biological tissue comprising an extracellular matrix (ECM) composition that includes mesothelial tissue. | 04-09-2015 |
| 20150297639 | TREATING CANCER - The specification provides compositions and methods for treating cancer with non cancerous cell extracellular vesicles. Extracellular vesicles act as a surrogate microenvironment to reverse the drug-resistance or cancerous phenotype of cancer cells towards a non cancerous phenotype. | 10-22-2015 |
| 20150366913 | Biologic Scaffold For Prevention of Pulmonary Fibrosis - Provided herein are methods of preventing, lessening or treating pulmonary fibrosis in a subject. The methods comprise delivering an amount of a powdered extracellular matrix (ECM)-derived material to the respiratory system of the subject effective to prevent, lessen or treat pulmonary fibrosis in a subject. Also provided is an apparatus for delivering the powdered ECM-derived material to a subject. | 12-24-2015 |
| 424553000 | Liver | 21 |
| 20080213388 | ECM TO FILL A SPACE CREATED AFTER CANCEROUS TUMOR EXCISION - Methods are described for using exogenous extracellular matrix (ECM) to fill a space created after cancerous tumor excision. The extracellular matrix promotes healing at the tumor excision site. Forms of ECM that can be used include exogenous mammalian ECM in sheets, particulate and emulsion. | 09-04-2008 |
| 20080254139 | METHODS AND COMPOSITIONS TO TREAT OVARIAN CANCER - The invention is a method of treating ovarian cancer by contacting a post-surgical site of an ovarian cancer patient with a composition or a sheet article comprising extracellular matrix to inhibit cancer cell attachment, promote wound healing after the surgery, reduce scar formation at the surgical site, regenerate lost tissue, and prevent tumor recurrence at the site or in the peritoneum generally. | 10-16-2008 |
| 20080260853 | EXTRACELLULAR MATRIX AS SURGICAL ADJUNCT IN A LUMPECTOMY PROCEDURE - The invention an article or composition of mammalian extracellular matrix (ECM) for placement in a lumpectomy space of a breast after tumor removal. The extracellular matrix article or composition can regenerate lost breast tissue, reduce the formation of scar tissue at the site of excision, and reduce a likelihood of local tumor recurrence at the lumpectomy site. The article can be sheet ECM, and the composition can be particulate ECM or emulsion or gel ECM. | 10-23-2008 |
| 20110305772 | COMPOSITIONS AND METHODS FOR EX VIVO HEPATIC NUCLEIC ACID DELIVERY - The invention provides compositions and methods for delivery of nucleic acids to the liver ex vivo. The method includes slow, low pressure infusion of the nucleic acid into the liver to efficiently transduce cells with minimal cell damage. | 12-15-2011 |
| 20120070507 | Compositions and Methods for the Treatment of Soft Tissue Injury - Provided herein are compositions and methods for the treatment of soft tissue injury, sports-related injury, physical overuse of muscles, ligaments or joints, and trauma, traumatic stress or sudden jolts on bones and tissues in an individual. Described herein are pharmaceutical compositions comprising a vasoconstrictor and, optionally, a topical analgesic and methods of using said compositions for the treatment of a variety of soft tissue injuries. | 03-22-2012 |
| 20120321723 | MICROVESICLES (MVS) DERIVED FROM ADULT STEM CELLS FOR USE IN THE THERAPEUTIC TREATMENT OF A TUMOR DISEASE - The invention is in the field of therapeutic treatment of tumours. The inventors have found that microvesicles derived from adult stem cells exert a remarkable anti-tumour effect when administered to a patient affected by a tumour disease. Preferred microvesicles are derived from a bone marrow-mesenchymal stem cell, a glomerular mesenchymal stem cell or a non-oval liver stem cell. | 12-20-2012 |
| 20130078314 | TRANSDERMAL METHOD OF DELIVERING NUTRIENTS INTO HUMAN BODY - The present invention is about a transdermal method that deliveries nutrients from fresh animal organs to the systemic circulation of the human body by applying the juice or chopped pieces of the fresh animal organs on the skin of the human body and allowing the nutrients to absorb through the layers of the exposed skin. The present invention aims to preserve the Yin and Yang energies naturally present in fresh organs and other foods that are lost in cooking and processing of foods. The present invention uses the full skin area transdermal delivery method by soaking the whole body in the juice of the fresh animal organs as well as the partial skin area transdermal delivery method by exposing certain parts of the human skin area to the fresh juices or chopped fresh animal organs and allowing the nutrients to enter the systemic circulation of the human body. | 03-28-2013 |
| 20130129833 | Compositions for Regenerating Defective or Absent Myocardium - Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function. | 05-23-2013 |
| 20140134264 | USE OF MICROVESICLES (MVs) DERIVED FROM STEM CELLS FOR PREPARING A MEDICAMENT FOR ENDO/EPITHELIAL REGENERATION OF DAMAGED OR INJURED TISSUES OR ORGANS, AND RELATED TO IN VITRO OR IN VIVO METHODS - The invention relates to the use of microvesicles (MVs) derived from stem cells for preparing a medicament for the endo/epithelial regeneration of damaged tissues or organs and/or for inhibiting the apoptosis induced by cytostatic agents. The stem cell from which the microvesicles are obtained is preferably selected from the group consisting of endothelial progenitor cells (EPCs), mesenchimal stem cells (MSCs), renal progenitors CD133+, adult human liver stem cells (HLSC) and any combination thereof. The microvesicles may be used in both in vitro and in vivo applications, such as for example the regeneration of damaged tissues or organs and the treatment of renal injury and hepatic injury, particularly acute renal failure (ARF) and acute hepatic failure (AHF). | 05-15-2014 |
| 20140242183 | Compositions for Regenerating Defective or Absent Myocardium - Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function. | 08-28-2014 |
| 20140242184 | Compositions for Regenerating Defective or Absent Myocardium - Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function. | 08-28-2014 |
| 20150301066 | Biomarkers For The Identification of Liver Damage - Methods and kits for characterizing liver damage in an individual are provided. The methods employ the use of immune analytes as biomarkers for detecting liver damage and predicting the likelihood that an individual suffering from liver damage will experience life-threatening liver failure. Concentration values for serum albumin and other identified immune analytes are obtained or determined from a blood sample taken from the individual. The obtained concentration values are then compared to corresponding concentrations from individuals having a healthy liver. By comparing the concentrations, an individual's likelihood of developing life-threatening liver failure and needing a liver transplant within a given time period (e.g., 6 months) can be identified. | 10-22-2015 |
| 20150306148 | COMPOSITIONS AND METHODS RELATED TO ORGAN OR TISSUE DECELLULARIZATION - Embodiments include methods for decellularizing an organ or tissue comprising conditioning the organ or tissue to be decellularized by exposing the organ or tissue to electricity, as well as methods of using such decellularized organs or tissues. | 10-29-2015 |
| 20160038644 | Compositions for Regenerating Defective or Absent Myocardium - Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function. | 02-11-2016 |
| 20160058910 | METHOD FOR PREPARING PARTICULATE DECELLULARIZED TISSUE - A particulate decellularized tissue is provided which shows sufficiently effective tissue regeneration and does not show cytotoxicity when used as material for cell culture. In accordance with the method for preparing a particulate decellularized tissue comprising a step of applying a high hydrostatic pressure to animal-derived tissues in a medium, a particulate decellularized tissue is obtained which does not show cytotoxicity but shows the effect of cellular attraction and the effect of induction of cellular differentiation and shows a high effect of tissue regeneration. | 03-03-2016 |
| 20160129047 | CONDITIONED MEDIUM FROM HUMAN ADULT LIVER STEM CELLS AND ITS USE IN THE TREATMENT OF LIVER DISORDERS - The invention relates to cell-free compositions obtained by culturing adult-derived human liver stem/progenitor cells (ADHLSC) in cell culture medium and isolating the resulting conditioned medium (ADHLSC-CM) that has advantageous property ties, such as anti-fibrotic effects. ADHLSC-CM, compositions based on ADHLSC-CM, and other related and derived products, can be used in cell culture processes or as a medicament, more particularly for the treatment of diseases involving organ injury, organ failure, in organ or cell transplantation or the pathological disruption, inflammation, degeneration, and/or proliferation of cells within a tissue or an organ, in particular within liver. | 05-12-2016 |
| 20160129153 | METHODS OF MANUFACTURING BIOACTIVE GELS FROM EXTRACELLULAR MATRIX MATERIAL - The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels. | 05-12-2016 |
| 20160184479 | TISSUE-BASED COMPOSITIONS AND METHODS OF USE THEREOF - Compositions comprising extracellular matrix (ECM) materials and methods of use thereof are disclosed. The compositions may comprise two or more ECM materials derived from different types of tissues, such as, e.g., lung tissue and spleen tissue, formulated for administration to a patient or configured as a medical device for implantation in or application to the patient. The compositions may combine complementary properties of different types of ECM materials for customized patient-specific and/or site-specific tissue repair and/or regeneration. | 06-30-2016 |
| 424554000 | Fish liver oil or solidified form thereof | 3 |
| 424555000 | Cod liver oil or solidified form thereof | 3 |
| 20110052719 | DERMATOLOGICAL COMPOSITION THAT CAN BE USED IN PARTICULAR FOR THE CARE AND PREVENTION OF ESCHARS - The invention relates to a composition formulated for a topical application to the skin containing, as essential constituents, peroxide lipids that have a degree of peroxidation between 30 and 500 milliequivalents per kg of peroxide lipids and cod liver oil. This composition can be used as a medical device, in order to form a protective film on the skin, especially for the care of irritated skin and/or skin that has red spots and/or skin that has superficial lesions, and/or as an adjuvant in skin massaging operations. It is most particularly useful for the care and/or prevention of eschars. | 03-03-2011 |
| 20110165260 | ALLANTOIN-CONTAINING SKIN CREAM - An allantoin-containing skin cream composition can comprise allantoin and at least one anionic or nonionic emulsifier that is substantially hydrophilic and is soluble in water. The composition is in the form of an oil-in-water emulsion. The pH of the composition is in a range of from about 3.0 to about 6.0; preferably, the pH of the composition is from about 5.0 to about 6.0. The composition can further comprise an acidic anionic polymer. A preferred acidic anionic polymer is a carboxypolymethylene polymer. The composition can further comprise a carbohydrate polymer such as galactoarabinan, polygalactose or polyarabinose. The composition can additionally comprise other ingredients such as herbal extracts, an antioxidant component, an emollient component, a chelator, a solvent component, or a preservative component. The composition is useful as a skin protectant. | 07-07-2011 |
| 20160058814 | PLANT EXTRACTS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS - Ehanolic plant extracts of aerial parts of at least a first plant, a second plant and optionally a third plants are described with related compositions, methods and systems, in which the first plant belongs to plant genus | 03-03-2016 |
