| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 424780320 | Heterocyclic monomer | 41 |
| 20080226585 | Method for Treating Surfaces with Copolymers - The present invention relates to a method for treating at least a surface of a substrate containing labile hydrogen atoms to confer to it cytotoxic properties or cell-adhesion properties, characterized in that it comprises at least a step consisting of exposing, within a liquid medium, said substrate or a surface thereof with at least a copolymer, said copolymer containing at least a monomer unit of type A including at least a reactive site able to attach to said substrate or said surface by covalent bonds and at least a monomer unit of type B including at least one molecule able to confer antimicrobial, antiviricidal and/or antifungicidal or cell-adhesion properties to said substrate or said surface, said step being carried out in efficient conditions to promote the covalent grafting of said copolymer to said substrate or a surface thereof. | 09-18-2008 |
| 20080279809 | COATING MATERIAL FOR METAL SURFACES HAVING ANTIADHESIVE PROPERTIES - A composition curable by polymerization, as well as a process of applying the composition and metal substrates coated therewith, the composition comprising: a) at least one metal compound which reacts before and/or during the curing of the composition by polymerization, with at least one of components b), c) or, if present, d), so that the metal is bound in the cured composition, the metal being selected from silicon, titanium, zirconium, manganese, zinc, vanadium, molybdenum and tungsten; b) at least one monomer or oligomer which contains at least one carboxyl or ester group and at least one olefinic double bond and which has no polyether chain of at least five ethylene oxide and/or propylene oxide units; c) at least one compound which contains both a polyether chain of at least five ethylene oxide and/or propylene oxide units and at least one carboxyl or ester group having at least one polymerizable double bond; and optionally d) at least one initiator for free radical and/or cationic polymerization and/or e) a biocidal active. | 11-13-2008 |
| 20080286225 | Antimicrobial and Antiviral Product - An antimicrobial and/or antiviral polymer is provided. The polymer is a modified polymer of a precursor polymer that comprises nitrogen atoms. The precursor polymer is modified into the antimicrobial and/or antiviral polymer of the present invention by substituting at least part of the nitrogen atoms with a (C | 11-20-2008 |
| 20080317703 | Novel Composition for Xerostomia - An oral care composition is described for use in the treatment or alleviation of the symptoms of dry mouth comprising polyvinyl pyrrolidone (PVP) or a derivative thereof, an anionic mucoadhesive polymer and an orally acceptable carrier or excipient. | 12-25-2008 |
| 20090047233 | Method for removing Phosphate and Polymer Used Therefore - Polymers and compositions utilizing such polymers are disclosed for treating hyperphosphatemia and other illnesses associated with elevated serum phosphate levels. Phosphate binding polymers, or a pharmaceutically acceptable salt of the polymers, comprise pendent groups extending from a backbone of the polymer. Each pendent group comprises at least two nitrogen-bearing functional groups which bind phosphate. Variations of such polymer and compositions are disclosed. | 02-19-2009 |
| 20090074709 | METHODS, DEVICES AND SYSTEMS FOR BIOCIDAL SURFACE ACTIVITY - A method of applying a biocidal polymer to a surface including applying a solution of the biocidal polymer to the surface, wherein the biocidal polymer includes biocidal groups and the biocidal polymer is insoluble in water. The biocidal groups can be selected from the group consisting of quaternary salt groups or haloamino groups. | 03-19-2009 |
| 20090104144 | Gypsum board with a fluorine-containing antifungal agent - A novel gypsum board having improved antifungal properties is disclosed. The board comprises a gypsum core, front and back paper facings, and a polymeric antifungal agent effective at inhibiting fungal growth. A preferred polymeric antifungal agent is polyDADMAC or polyTMMC. The novel gypsum board further comprises a non-polymeric antifungal agent comprising a fluorine-containing quaternary ammonium compound. Preferred non-polymeric ammonium compounds include Tetra-n-butylammonium fluoride and Tetraethylammonium fluoride. The polymeric antifungal agent can be present in the gypsum core and/or on one or both of the paper facings. The non-polymeric antifungal agent may be encapsulated in a material or ionically associated with the polymeric antifungal agent to allow releases of the non-polymeric antifungal agent over time and/or upon exposure to moisture. Methods for preparing the aforementioned novel gypsum board are also disclosed. | 04-23-2009 |
| 20090130051 | Flavonoid Compounds and Uses Thereof - Novel flavonoid compounds having anti-oxidant activity are described. The compounds and compositions have been shown to exhibit anti-oxidant properties and are particularly useful in the treatment of ischemia and reperfusion injuries. The invention also describes a method to chemically synthesize such flavonoid compounds and test their efficacy. Such compounds and corresponding pharmaceutically acceptable derivatives and/or salts have uses in the areas of pharmaceuticals, nutraceutical, and veterinary applications. | 05-21-2009 |
| 20090148396 | BIOCOMPATIBLE BIODEGRADABLE FUMAGILLIN ANALOG CONJUGATES - Fumagillin analog polymer conjugates, methods of making fumagillin analog polymer conjugates, compositions comprising a polymer conjugate of a fumagillin analog, and methods for treating cancer, or treating angiogenic diseases comprising administering to a subject in need thereof an effective amount of a polymer conjugate of a fumagillin analog, are described. Also described are novel fumagillin analogs, methods of making fumagillin analogs, compositions comprising at least one fumagillin analog, and methods for treating cancer, or treating angiogenic diseases comprising administering to a subject in need thereof an effective amount of a fumagillin analog. | 06-11-2009 |
| 20100040573 | CATIONIC POLYMERS AS THICKENERS FOR AQUEOUS AND ALCOHOLIC COMPOSITIONS - The present invention relates to a method for producing polymers by radically polymerizing a mixture comprising 99.99 to 10% by weight of at least one α,β-ethylenically unsaturated compound with at least one cationogenic and/or cationic group per molecule, 0 to less than 25% by weight of at least one monoethylenically unsaturated amide-group-containing compound different from a) and also 0.01 to 5% by weight of a crosslinker using at least two different water-insoluble initiators. | 02-18-2010 |
| 20100247478 | METHOD FOR STABILIZING VERTEBRAL BODY ARCHITECTURE - A method for reducing the occurrence of new post-operative fractures in vertebrae of a patient's spine after a vertebroplasty procedure performed to stabilize a fracture in a vertebra of a patient comprising the steps of performing a vertebroplasty procedure to stabilize a fracture in a vertebra of the patient, wherein the vertebroplasty procedure comprises the step of injecting a material into the fractured vertebra, wherein the material is formed by mixing together a first paste and a second paste, wherein the first paste comprises at least one of a polymerizable monomer and a filler, and wherein the second paste comprises at least one of a polymerizable monomer and a filler. | 09-30-2010 |
| 20100272672 | CROSSLINKED HYDROGELS - The present invention preferably provides for a method of forming and the resulting solid polymer gel composition comprising polyethylene imine and at least one hydrogen bonding polymer. The composition has a greater viscosity than either of the polyethylene imine or the hydrogen bonding polymer alone and is injectable immediately after mixing of the polyethylene imine and the at least one hydrogen bonding polymer. A method of tissue repair may include mixing about 9.25% (w/w) to about 13.65% (w/w) polyethylene imine and about 18.02% (w/w) to about 26.62% (w/w) polyvinyl alcohol to form an injectable composition; injecting the injectable composition into a cavity within a human body; and allowing the composition to solidify in situ. A kit may include a multi-barrel syringe at least one barrel is loaded with polyethylene imine and at least another barrel is loaded with at least one hydrogen bonding polymer. | 10-28-2010 |
| 20100284959 | SEQUENCE SPECIFIC DOUBLE-STRANDED DNA/RNA BINDING COMPOUNDS AND USES THEREOF - The present invention provides specific double-stranded DNA/RNA binding compounds having a polymeric structure, which are in fact, triplex forming molecules capable of binding tightly and specifically to predetermined sequences in the major groove of double stranded nucleic acid molecules; as well as pharmaceutical compositions comprising thereof. The triplex forming molecules and the pharmaceutical compositions of the invention can be used for various therapeutic applications such as site-specific modulation of gene expression and targeting of DNA or RNA damage, as well as for diagnostic applications in vitro. | 11-11-2010 |
| 20100297057 | PESTICIDE COMPOSITIONS EXHIBITING ENHANCED ACTIVITY AND METHODS FOR PREPARING SAME - Pest controlling compositions exhibiting enhanced pesticidal activity levels and methods for preparing the same are disclosed. In one embodiment, a method includes providing a liquid composition that includes at least one pesticide and at least one co-ingredient that enhances pesticidal activity of the composition compared to a composition dissimilar only in not having the at least one co-ingredient. The at least one co-ingredient may include at least one metal oxide, a combination of at least one transition metal salt and at least one proteinaceous material or a combination of at least one proteinaceous material and at least one polymeric material. The method further includes spray drying the liquid composition to provide a solid composition. In one aspect of this embodiment, the solid composition provided by the spray drying exhibits enhanced pesticidal activity compared to the liquid composition. | 11-25-2010 |
| 20100310498 | ACTIVE AGENTS AND THEIR OLIGOMERS AND POLYMERS - Conjugates comprising at least two active agents linked by a diglycolic acid or polyglycol diacid linker are disclosed. The invention also concerns oligomers and polymers of these conjugates and their use in therapeutic and industrial applications for localized, immediate or fast release delivery of an active agent, such as an anti-microbial, anti-infective, or antiseptic agent. | 12-09-2010 |
| 20110189120 | AEGYPTIN AND USES THEREOF - The present invention relates to the discovery of the Aegyptin gene and Aegyptin protein, a molecule that interacts with collagen and inhibits platelet adhesion, activation and aggregation. Novel biological tools, prophylactics, therapeutics, diagnostics, and methods of use of the foregoing are also disclosed. | 08-04-2011 |
| 20110195042 | Compositions, Methods and Kits Useful for Treating a Respiratory Symptom - The present disclosure describes methods for enhancing an overall cooling sensation of an oral mucosa comprising administering a liquid composition comprising a thickening agent and/or a mucoadhesive polymer, a non-menthol coolant; and contacting the oral mucosa with the liquid composition. The disclosure also describes the liquid compositions. | 08-11-2011 |
| 20120027716 | Povidone Iodine, A Novel Alternative Preservative For Ophthalmic Compositions - The invention includes a preserved ophthalmic preparation comprising povidone-iodine (PVP-I) at a concentration sufficient to preserve the ophthalmic preparation, and at least one member selected from the group consisting of a steroidal anti-inflammatory compound, a non-steroidal anti-inflammatory compound, an antibacterial compound, an anti-allergy compound, and an anti-glaucoma compound. The invention also includes adding PVP-I to an ophthalmic composition in order to preserve the composition, wherein the PVP-I is added at a concentration sufficient to preserve the composition. | 02-02-2012 |
| 20120076750 | FIBRIN BASED GLUE WITH FUNCTIONALIZED HYDROPHILIC POLYMER PROTEIN BINDING AGENT - The present invention provides a non-liquid biomaterial that may be used as a surgical sealant, a suture support, a blood flow controller, an adhesion reducing agent, an adhesion preventing agent, a tissue support, a tissue filler, a wound dressing or a combination thereof. The non-liquid biomaterial may comprise a blood derived material such as plasma, platelet poor plasma, platelet rich plasma or a material derived from blood containing tissue aspirate, such as bone marrow aspirate, a protein binding agent and a polymerizing agent. Methods for making and using the non-liquid biomaterial are also provided. | 03-29-2012 |
| 20120288469 | ANTIMICROBIAL SOLID AND METHODS OF MAKING AND USING SAME - A solid material adapted to kill bacteria in planktonic, spore and biofilm states is lethal toward a wide spectrum of gram positive and gram negative bacteria as well as other microbes. The solid material includes a significant amount of one or more surfactants entrained in a crosslinked polymeric network. | 11-15-2012 |
| 20130039881 | COMBINATION FOR THE TREATMENT OF RADIATION- OR CHEMOTHERAPY-INDUCED MUCOSITIS - The present invention relates to the use of a combination of glycine, proline, and optionally a natural or synthetic film-forming polymer, and/or lysine and/or leucine, to prepare a composition for the treatment of mucositis induced by radiation or chemotherapy. | 02-14-2013 |
| 20130101547 | THERMORESPONSIVE COMPOSITIONS FOR DERMATOLOGICAL USE AND METHODS THEREOF - The present specification generally relates to compositions comprising a thermoresponsive polymer and methods of treating a soft tissue condition using such compositions. | 04-25-2013 |
| 20130108575 | ANTIBACTERIAL AND ANTIFUNGAL PEPTIDES | 05-02-2013 |
| 20130108576 | STABLE ANTISEPTIC COMPOSITIONS AND METHODS | 05-02-2013 |
| 20130183263 | PHARMACEUTICAL COMPOSITIONS AND METHODS - Pharmaceutical compositions and kits including a tyrosine hydroxylase inhibitor; melanin, a melanin promoter, or a combination thereof; a p450 3A4 promoter; and a leucine aminopeptidase inhibitor are provided. Also provided are methods of treating cancer in a subject, comprising administering an effective amount of a tyrosine hydroxylase inhibitor, a melanin promoter, a p450 3A4 promoter, and a leucine aminopeptidase inhibitor to the subject in need thereof. Also provided are methods of reducing cell proliferation in a subject comprising administering an effective amount of a tyrosine hydroxylase inhibitor, a melanin promoter, a p450 3A4 promoter, and a leucine aminopeptidase inhibitor to the subject in need thereof. | 07-18-2013 |
| 20130295041 | Novel Composition - An oral care compositon is described for use in the treatment or alleviation of the symptoms of dry mouth comprising polyvinyl pyrrolidone (PVP) or a derivative thereof, an anionic mucoadhesive polymer and an orally acceptable carrier or excipient. | 11-07-2013 |
| 20140072526 | METHOD FOR THE PRODUCTION OF ADSORBATES OF A RASAGILINE SALT HAVING A WATER-SOLUBLE ADJUVANT - The present invention relates to an adsorbate of a pharmaceutically compatible rasagiline salt comprising at least one pharmaceutically compatible adjuvant, wherein the at least one pharmaceutically compatible adjuvant is a water-soluble, organic solvent and the rasagiline salt is present in the adsorbate as an amorphous substance. | 03-13-2014 |
| 20140147410 | MICROBICIDE COMBINATIONS CONTAINING SILVER - A synergistic microbicidal composition. The composition comprises: (a) silver ion; and (b) diiodomethyl-p-tolylsulfone; wherein a weight ratio of silver to diiodomethyl-p-tolylsulfone is from 1: 1/0.008 to 1/0.1, 1/0.13 to 1/8 or 1/120 to 1/280. | 05-29-2014 |
| 20140308236 | ANTIMICROBIAL COMPOSITION AND USES THEREOF - The present invention provides a composition including an antibacterial polymer bound to a synthetic water soluble polymer, methods of using the composition for avoiding bacterial growth and processes of making plastic material which include these antibacterial compositions. | 10-16-2014 |
| 20140314705 | THERMORESPONSIVE COMPOSITIONS FOR DERMATOLOGICAL USE AND METHODS THEREOF - The present specification generally relates to compositions comprising a thermoresponsive polymer and methods of treating a soft tissue condition using such compositions. | 10-23-2014 |
| 20140348779 | OPHTHALMIC COMPOSITION - A topical ophthalmic composition for treatment of dry eye is disclosed. In preferred embodiments, the composition comprises as active ingredients hyaluronic acid or a pharmaceutically acceptable salt thereof and polyvinylpyrrolidine. In other embodiments of the invention, the composition additionally comprises polyvinyl alcohol. Methods of preparation of the composition are disclosed, as well as methods for use of the composition in the treatment of dry eye. | 11-27-2014 |
| 20150044161 | MULTIFUNCTIONAL POLYMERS - Described herein are multifunctional polymers comprising a first repeating unit having at least one pseudo-cationic moiety, a second repeating unit having at least a hydrophobic moiety, and a third repeating unit, where the weight-average molecular weight is less than about 10,000 Da. In one embodiment the polymers exhibit antimicrobial activity. Also provided are compositions formulated with the multifunctional polymers, and a method of providing antimicrobial activity. | 02-12-2015 |
| 20150290279 | PHARMACEUTICAL COMPOSITIONS AND METHODS - Pharmaceutical compositions and kits including a tyrosine hydroxylase inhibitor; melanin, a melanin promoter, or a combination thereof; a p450 3A4 promoter; and a leucine aminopeptidase inhibitor are provided. Also provided are methods of treating cancer in a subject, comprising administering an effective amount of a tyrosine hydroxylase inhibitor, a melanin promoter, a p450 3A4 promoter, and a leucine aminopeptidase inhibitor to the subject in need thereof. Also provided are methods of reducing cell proliferation in a subject comprising administering an effective amount of a tyrosine hydroxylase inhibitor, a melanin promoter, a p450 3A4 promoter, and a leucine aminopeptidase inhibitor to the subject in need thereof. | 10-15-2015 |
| 20150366900 | CONDUCTIVE BIOMATERIAL FOR ENHANCEMENT OF CONDUCTION IN VITRO AND IN VIVO - A biocompatible, electrically conductive biomaterial capable of earn carrying the electrical potential of a cardiac impulse and comprising (1) a conductive polymer such as polyaniline, polypyrrole or polythiophene, and (ii) a biocompatible component such as a polysaccharide, a protein, or a polypeptide, in particular chitosan or gelatin, is described. The material can take the form of a hydrogel, membrane, sheet or mesh. It can be used to restore or improve electrical impulse propagation across damaged tissue or scar region of the myocardium, in particular in the ti treatment of myocardial infarction and arrhythmia. | 12-24-2015 |
| 20150368380 | ANTIMICROBIAL POLYMER - The invention is directed to an antimicrobial polymer that can preferably be processed thermoplastically, a method for the preparation of said antimicrobial polymer and its use in antimicrobial treatment. The invention is further directed to polymer blends containing antimicrobial polymers and the use of special monomers in the preparation of antimicrobial polymers that can be processed thermoplastically. | 12-24-2015 |
| 20160038558 | INTERVAL THERAPY FOR THE TREATMENT OF LOSS OF EYESIGHT IN HUMANS WITH GLAUCOMA AND OTHER DEGENERATIVE EYE DISEASES - Methods for the prevention and treatment of ocular disorders, in particular glaucoma, through blocking the toxic effects of β-amyloid (Aβ) derivatives, pharmaceutical compositions for effecting such prevention and interval treatment thereof. | 02-11-2016 |
| 20160038604 | METAL CHELATING COMPOSITIONS AND METHODS FOR CONTROLLING THE GROWTH OR ACTIVITIES OF A LIVING CELL OR ORGANISM - The present invention provides for metal chelating compositions which are soluble in aqueous media. The present invention also provides chelating compositions that possess acceptable iron sequestering strengths and are able to present a physical form that potentially inhibits (e.g. does not permit easy) access of iron sequestered by the compositions to the cells being targeted. Compositions comprising chelating aspects affixed to or incorporated into suitable carrier materials such that the resulting metal chelating composition is soluble in aqueous media are also provided. Disclosed herein are chelating compositions, for chelating one or more essential metals. The chelating compositions being soluble in an aqueous medium and comprising one or more metal binding chemical groups affixed to or incorporated into the structure of a carrier material, such that the resulting chelating composition is able to bind one or more metals, and remains substantially soluble in the aqueous medium with its bound metal or metals. | 02-11-2016 |
| 20160074400 | WNT MODULATORS FOR THE PROTECTION, MITIGATION AND TREATMENT OF RADIATION INJURY - Provided are composition and methods for treating radiation-induced cell damage, and in particular aspects to methods for protecting, mitigating or otherwise treating radiation-induced induced depletion of tissue stem cells and injury to the supportive stem cell niche, and in even more particular aspects to methods for protecting, mitigating or otherwise treating radiation-induced gastrointestinal syndrome (RIGS), comprising sequential administration of a Wnt pathway activator/agonist (e.g., Rspo1 or a small molecule inducer thereof) that amplifies the surviving intestinal stem cell (ISC) pool post-radiation exposure, followed by a selective antagonist of the β-Catenin-CBP interaction (e.g., ICG-001 or other exemplary compounds disclosed herein) that accelerates differentiation of the stimulated (e.g., Rspo1-stimulated) ISC in crypt-villi axis, promoting villous regeneration and intestinal restitution, thereby mitigating RIGS. Adjunctive and combination therapy embodiments are encompassed. | 03-17-2016 |
| 20160082124 | DRUG DELIVERY SYSTEM AND METHOD - A system for delivering a therapeutic dose of a drug is disclosed. The system includes a delivery medium with therapeutic units attached thereto. The delivery medium is preferably a polymeric hydrogel matrix that has therapeutic units incorporated therein or metal nanoparticles with therapeutic units complexed thereto. The therapeutic units include nucleic acid moieties. The nucleic acid moieties preferably include strands of nucleic acid and drug moieties complexed with the strands of nucleic acid. Where the system includes a polymeric hydrogel matrix, an active drug is controllably released from the polymer hydrogel matrix to provide a therapeutic dose to a biological system or biological tissue. The active drug is controllably released from the hydrogel matrix by altering the environment the hydrogel matrix, or by enzymatic cleavage of the nucleic acid moieties or by a combination thereof. | 03-24-2016 |
| 20160375093 | PHARMACEUTICAL COMPOSITIONS AND METHODS - Pharmaceutical compositions and kits including a tyrosine hydroxylase inhibitor; melanin, a melanin promoter, or a combination thereof; a p450 3A4 promoter; and a leucine aminopeptidase inhibitor are provided. Also provided are methods of treating cancer in a subject, comprising administering an effective amount of a tyrosine hydroxylase inhibitor, a melanin promoter, a p450 3A4 promoter, and a leucine aminopeptidase inhibitor to the subject in need thereof. Also provided are methods of reducing cell proliferation in a subject comprising administering an effective amount of a tyrosine hydroxylase inhibitor, a melanin promoter, a p450 3A4 promoter, and a leucine aminopeptidase inhibitor to the subject in need thereof. | 12-29-2016 |
| 20180021371 | NOVEL OPHTHALMIC COMPOSITION AND METHODS OF USE | 01-25-2018 |
