Entries |
Document | Title | Date |
20080233054 | DENTAL ANTI-HYPERSENSITIVITY COMPOSITION AND METHOD - The present invention relates to compositions and methods for calcifying dental tissue, e.g., preventing or treating dental hypersensitivity. An oral composition of arginine bicarbonate and calcium carbonate promotes the formation of dentinal tubule plugs aided by combining calcium and phosphate in the fluid. In a specific example, an arginine bicarbonate/calcium carbonate mixture blocked dentinal tubules in a model system. In addition to treating dentinal sensitivity, the compositions and methods of the invention provide for calcifying exposed tooth pulp, calcifying the base or all of a pit or fissure in a tooth, and treating a carious lesion. | 09-25-2008 |
20080241080 | COMPOSITION FOR TREATING XEROSTOMIA OR DRY MOUTH - The present invention provides a composition comprising olive oil, trimethylglycine and xylitol for treating xerostomia and disorders associated thereto, with very good results in increasing the unstimulated salivary flow, in alleviating the symptoms of xerostomia, including the pain associated to xerostomia, as well as improving the quality of life of affected persons. The composition of the invention has also been proved to protect dentin against demineralization in acid conditions. | 10-02-2008 |
20080253974 | N-Phenyl-N-Pyridinyl-Benzamides and Benzenesulfonamides Having Cooling Properties - Used as cooling agents are the compounds of formula (I), wherein Y is carbonyl (C(═O)) or sulfonyl (SO | 10-16-2008 |
20080292565 | TOOTH FLUORIDATING AND REMINERALIZING COMPOSITIONS AND METHODS, BASED ON NANOAGGREGATE FORMATION - Compositions and methods for forming, in an aqueous environment, a nanoaggregate of calcium fluoride and amorphous calcium phosphate-containing compound, such as amorphous calcium phosphate fluoride or amorphous calcium carbonate phosphate fluoride are described. The nanoaggregate (or nanocomposite) can release calcium, phosphate, and fluoride, and ultimately convert to the tooth mineral, fluorapatite. One method for forming such a nanoaggregate involves applying a non-aqueous (e.g., varnish-based) composition (e.g., a suspension), containing solid particles of water soluble salts of calcium, phosphate, and fluoride, to the aqueous environment of the mouth. This results in rapid solubilization of the salts, precipitation of the nanoaggregate, and tooth remineralization. Tooth fluoridation and remineralization may also be carried out by applying to the tooth a non-aqueous carrier containing the nanoaggregate. Whitening agents can also be added to these compositions and methods. | 11-27-2008 |
20080292566 | ORAL COMPOSITION CONTAINING MORIN - The present invention relates to an oral composition useful to reduce inflammatory processes. More specifically, the invention relates to a composition consisting essentially of an anti-oxidative effective amount of morin and a water-humectant phase, and to a composition comprising an anti-oxidative effective amount of morin, one or more anti-bacterial agents and a water-humectant phase. In an embodiment, the composition is used in a method of preventing or treating inflammatory dental diseases such as gingivitis and periodontitis. | 11-27-2008 |
20080311054 | Compositions and Methods to Counteract Oral Malodour - The invention relates to hedonistically pleasing oral malodour counteracting compositions including flavour compositions and oral care products, methods to form such compositions and methods to counteract oral malodour. The compositions comprises 2 or more of oral malodour counteracting actives of formula I in a total concentration of at least 10% (w/w) based on the total concentration of flavour ingredients, and an individual concentration of 1% or more per oral malodour counteractant, based on total flavour ingredients. The maximum concentration of any individual oral malodour counteracting active based on the total of oral malodour counteracting actives is 70%. The identified oral malodour counteracting actives are various flavour compounds and natural ingredients. | 12-18-2008 |
20080311055 | MONO-, DI- AND POLYOL ALKOXYLATE PHOSPHATE ESTERS IN ORAL CARE FORMULATIONS AND METHODS FOR USING SAME - This invention relates to a composition useful as an oral care composition comprising an organophosphate material, additional oral care composition ingredients, for example, a surfactant agent, and optionally an abrasive agent. | 12-18-2008 |
20080317681 | Compositions containing a stain removing complex, and methods of making and using the same - A composition in the form of a chewing gum composition, a confectionery composition or consumable film composition containing a stain removing complex including a stain removing agent having therapeutic properties and a cyclodextrin compound and methods of preparing and using the same to remove stains from dental material including teeth. | 12-25-2008 |
20090004121 | Combination of picotamide with nafronyl - The invention relates to a combination of picotamide(N,N′-bis-(3-picolyl)-4-methoxy-isophthalamide) and nafronyl(2-diethylaminoethyl 2-(naphthalen-1-ylmethyl)-3-(oxolan-2-yl)propanoate), pharmaceutical compositions, and use of this combination in the treatment of intermittent claudication. | 01-01-2009 |
20090022672 | FLUORIDE COMPOSITION AND METHODS FOR DENTAL MINERALIZATION - The present invention relates to compositions and methods for mineralizing a dental surface or subsurface including providing a composition including stabilized ACP and a source of fluoride ions. | 01-22-2009 |
20090028802 | ORGANOLEPTICALLY ACCEPTABLE INDOLE SEROTONIN RECEPTOR AGONIST ORAL DOSAGE FORMULATIONS AND METHODS OF USING THE SAME - Organoleptically acceptable oral dosage formulations of an indole receptor serotonin agonist, and methods of making and using the same, are provided. An aspect of the formulations is that they include an indole receptor serotonin agonist and a masking component. In certain embodiments, the masking component includes one or more of an amino acid and an organic acid. The subject invention finds use in a variety of applications. | 01-29-2009 |
20090035226 | USE OF CRANBERRY EXTRACT ENRICHED IN TOTAL PHENOLS AND FREE, ESSENTIALLY FREE, OR SUBSTANTIALLY FREE OF SUGARS, ACIDS, SULFUR AND OTHER CONTAMINANTS, FOR PERIODONTAL TREATMENT - Cranberry and other plant extracts enriched in total phenols and free or substantially free of sugars, acids, sulfur and other contaminants are used for periodontal treatments. The periodontal treatments of the present invention include swish and swallow techniques, in which the extracts enriched in total phenols but free or substantially free of sugars, acids, sulfur and other contaminants, are solubilized in water or other solvent, placed in the mouth, swished around the teeth and then swallowed. Other application techniques include gel applications, gum formulations and toothpaste formulations. | 02-05-2009 |
20090047221 | COMPOUNDS AND COMPOSITIONS USEFUL IN THE TREATMENT OF NEOPLASIA - There is described compounds for use in therapy, said compounds being defined by Formula (1): There is also described an anti-proliferative composition comprising one or more compounds according to Formula (1), and a method of treatment of neoplasia comprising the administration of such a compound or composition. | 02-19-2009 |
20090092560 | TRIVALENT CHROMIUM COMPOUNDS, COMPOSITIONS AND METHODS OF USE - The present invention provides chromium compounds, specifically chromium dinicocysteinate, which possess the ability to improve insulin sensitization, glucose tolerance, bioavailability, efficacy, and safety, and methods for their use. | 04-09-2009 |
20090098066 | Substituted bicyclo [2.2.2] oct/5-ene compounds and their use as cooling agents - Used as cooling agents are the compounds of 1/7-isopropyl-4/5-methyl-bicyclo[2.2.2]oct-5-ene derivatives of the formula (I) | 04-16-2009 |
20090117056 | Probiotic oral dosage forms - Provided are probiotic compositions that have enhanced stability under various storage conditions. The stability of the probiotic compositions is enhanced through the addition of various agents and excipients. Examples of agents and excipients that may be used to enhance the stability of probiotic compositions include prebiotics, such as the sugar alcohols mannitol, sorbitol, and lactitol, and/or phytonutrients such as oligomeric proanthocyanidins (OPCs). The probiotic compositions may be formulated into oral dosage forms such as tablets, caplets, and capsules, or manufactured as a chewing gum or as a powder formulation that may be dissolved in a liquid such as water, milk, juice, or yogurt. | 05-07-2009 |
20090142281 | Composition Comprising A Coupled Enzyme System - The present invention relates to a composition comprising a coupled enzyme system for the rapid and efficient production of hydrogen peroxide by the coupling of a first enzyme system capable of hydrogen peroxide generation, to a second enzyme system which utilizes the non hydrogen peroxide product of the first enzyme system, and optionally is capable of generating further hydrogen peroxide. | 06-04-2009 |
20090155188 | MOUTH ENVIRONMENT WITH ORAL COMPOSITION - A solid oral composition for providing a mouthwash efficacious effect comprising a non-hygroscopic base, carbamide peroxide, a bacterial immobilizing and sulfur sequestration agent, and an optional antioxidant enzyme. | 06-18-2009 |
20090155189 | Preparations, Methods and Kits Useful for the Treatment of Cough - The invention relates to a respiratory preparation providing cough relief in a human comprising: a thickening agent; a benefit agent. Additionally, the invention relates to a method of providing cough relief in a human comprising: the steps of administering to a human a respiratory preparation comprising: a thickening agent; a benefit agent. | 06-18-2009 |
20090155190 | Tooth Whitening Compositions and Delivery Systems Therefor - Stain-removing oral compositions, such as gum compositions, are herein provided. The gum compositions include a film-forming agent, such as a fatty acid salt, in combination with an abrasive and a chelating agent. The fatty acid salt may be a salt derived from a hydroxy fatty acid. The chelating agent may be a polyphosphate and the abrasive may be a silica abrasive. | 06-18-2009 |
20090169488 | Acidic solid oral compositons without erosive potential in saliva and method for determining erosive potential in saliva - Acidic oral compositions having calcium contents and effective pH-values in the area indicated by grey tone in FIG. | 07-02-2009 |
20090169489 | COBALAMIN COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING MUCOSITIS - The present invention relates to troches, patches, gels, or viscous liquids for topical treatment or prevention of mucosal surfaces containing as an active ingredient molecules of cobalamin for the treatment of inflammatory, ulcerative and painful conditions of mucosal surfaces such as mucositis, stomatitis, vestibulitis, aphthous ulcerations, and Behcet's syndrome. For reducing the incidence, duration, and pain levels of recurrent aphthous ulcers, bioactive cobalamin may delivered with adhering discs that stick to a tooth. | 07-02-2009 |
20090169490 | COMPOSITION AND METHOD FOR WEIGHT LOSS - A weight loss composition consisting of 1 to 10 weight parts of L-hydroxy citric acid and 1 to 10 weight parts of L-carnitine tartrate as active components, and pharmaceutically or food-acceptable carrier is disclosed. The present composition can be made to tablet, capsule, oral juice or chewing gum which shows great effect of weight loss. | 07-02-2009 |
20090175803 | METHOD AND COMPOSITIONS FOR ADMINISTERING RESVERATROL AND PTEROSTILBENE - Resveratrol and/or pterostilbene are added to a chewable carrier, to enhance absorption of resveratrol and/or pterostilbene buccally or through the mucous membranes of the mouth. The composition containing the resveratrol and/or pterostilbene is designed to be retained in the mouth for at least 20 seconds and up to 20 minutes to ensure absorption of the resveratrol and/or pterostilbene through the mucous membranes of the mouth. | 07-09-2009 |
20090180971 | Method for the prevention and/or activation of defense mechanisms in the human body against conditions, disorders or diseases relating to the presence of free radicals, such as: environmental pollution, aging or smoking - The invention provides a method for the prevention and/or activation of defense mechanisms in the human body against conditions, disorders or diseases relating to the presence of free radicals, such as; environmental pollution, aging or smoking by rising the administration to a mammal, namely a human being, of an effective amount of a phytonutrient-and-citric-based edible dosage, during or after tobacco consumption and which is intended to prevent pathologies, conditions, disorders or diseases relating to the presence of free radicals in the human body. Likewise, the therapeutic method of the invention enables activation of defense mechanisms in the human body to reduce conditions, disorders or diseases relating to the presence of free radicals in the body. | 07-16-2009 |
20090196834 | Tobacco alkaloid releasing chewing gum - The invention relates to a tobacco alkaloid releasing chewing gum comprising tobacco alkaloid, gum base, and chewing gum ingredients, said gum base comprising elastomer and resin-compounds constituting an amount in the range of about 2 to 20% by weight of said chewing gum. | 08-06-2009 |
20090208425 | TRANSMUCOSAL ADMINISTRATION OF 2,3-DIMETHOXY-5-METHYL-6-(10-HYDROXYDECYL)-1,4-BENZOQUINONE - Use of idebenone for the preparation of a medicament for transmucosal administration. | 08-20-2009 |
20090214445 | DELIVERY SYSTEMS FOR MANAGING RELEASE OF FUNCTIONAL INGREDIENTS IN AN EDIBLE COMPOSITION - A delivery system for inclusion in an edible composition is formulated to have at least one ingredient encapsulated with an encapsulating material. The delivery system and the resulting edible composition may include other ingredients to create a desired release profile for the at least one ingredient. | 08-27-2009 |
20090238773 | Use of Morpholino Compounds for the Treatment of Halitosis - Use of a morpholino compound having the general formula (I) wherein R | 09-24-2009 |
20090238774 | Use of lactic acid bacteria for decreasing gum bleeding and reducing oral inflammation - The invention herein relates to the use of nonpathogenic, anti-inflammatory and anti-bleeding lactic acid bacteria strains, and products and methods using such strains for treatment and prophylaxis of bleeding gum and gingivitis caused by oral inflammation. | 09-24-2009 |
20090238775 | MONO-, DI- AND POLYOL ALKOXYLATE PHOSPHATE ESTERS IN ORAL CARE FORMULATIONS AND METHODS FOR USING SAME - This invention relates to a composition useful as an oral care composition comprising an organophosphate material, additional oral care composition ingredients, for example, a surfactant agent, and optionally an abrasive agent. | 09-24-2009 |
20090252690 | Flavoured Mouth Wash Composition - The present invention provides a flavoured product comprising four or more flavour materials having antimicrobial properties and selected from the group comprising nonanol, decanol, nonanal, decanal, amyl propionate, anethole synthetic, anisic aldehyde, basil oil, benzyl benzoate, benzyl butyrate, benzyl formate, chamomile oil, cinnamic aldehyde, cis-3-hexenol, clove bud oil, damascone, ethyl acetoacetate, eucalyptus oil, ginger, isoamyl acetate, menthol laevo, methyl cinnamate, methyl salicylate, orange oil, rosemary oil, tarragon, Tea Tree oil, and peppermint oil: and one or more antimicrobial agents selected from the group comprising triclosan, pyrophosphates, zinc salts, cetylpyridinium chloride, parabens, stannous salts, sodium dodecyl sulphate, chlorhexidine, copper salts, strontium salts, peroxides and sanguinarine. | 10-08-2009 |
20090274632 | Identification of human T2R receptors that respond to bitter compounds that elicit the bitter taste in compositions, and the use thereof in assays to identify compounds that inhibit (block) bitter taste in composition and use thereof - The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds present in, e.g., coffee. Also, the invention relates to the discovery of specific compounds and compositions containing that function as bitter taste blockers and the use thereof as bitter taste blockers or flavor modulators in, e.g., coffee and coffee flavored foods, beverages and medicaments. Also, the present invention relates to the discovery of a compound that antagonizes numerous different human T2Rs and the use thereof in assays and as a bitter taste blocker in compositions for ingestion by humans and animals. | 11-05-2009 |
20090280070 | CHEWING GUM COMPRISING HYDROXYAPATITE - The present invention relates to a chewing gum comprising at least one gum base system, at least one chewing gum additive, and further comprising rod-shaped apatite crystals of the formula Ca | 11-12-2009 |
20090311197 | Method and Compositions for Oral Hygiene - The present invention comprises novel compositions and methods for oral hygiene and for treating and preventing oral disease in humans and in animals. In one embodiment, the novel compositions of the present invention comprise a unique oral hygiene solution that can be added to drinking water. The invention provides compositions and methods for maintaining oral health that are convenient to use and are formulated so that they are safe for regular use by humans and animals. | 12-17-2009 |
20100015065 | Compositions for food, process for producing the same, and functional foods and drinks containing the same - Black currant anthocyanin-containing compositions for foods comprising 1 to 25% by weight of black currant anthocyanin on the basis of solid matters; a process for producing a black currant anthocyanin-containing composition for foods characterized by purifying and concentrating black currant juice employed as a starting material by using a charged reverse osmosis membrane; functional foods and drinks characterized by containing the above compositions for foods; and the above-described compositions for foods and the above-described functional foods and drinks having an effect of improving visual function, a function of improving blood fluidity, and/or a function of lowering blood pressure. The conventional black currant anthocyanin compositions have a low black currant anthocyanin content, strong acidity and poor stability, which makes them unsuitable as additives for foods and drinks. However, the production process according to the present invention makes it possible to provide black currant anthocyanin-containing compositions for foods which have a high black currant anthocyanin content, an adequate acidity, and a high stability and can be added to foods and drinks. Moreover, functional foods and drinks containing these compositions, which have an effect of improving visual function, a function of improving blood fluidity, or a function of lowering blood pressure, can be provided. | 01-21-2010 |
20100028273 | METHODS AND KITS FOR CLEANING AND REMINERALIZING TEETH - Methods and associated kits for use in selectively conditioning and remineralizing teeth. An exemplary method comprises the steps of applying a conditioning composition to one or more of a person's teeth, and applying a remineralizing composition to the person's teeth. The conditioning composition includes a conditioning agent, and the remineralizing composition includes a remineralizing agent comprising calcium ions and/or fluoride ions. The conditioning composition may be applied prior to or after application of the remineralizing composition. In one embodiment, both the conditioning composition and the remineralizing composition include different remineralizing ions (e.g., one including calcium, one including fluoride). | 02-04-2010 |
20100040563 | Solubilization of Cyclohexane-Based Carboxamide Derivatives for Use as Sensates in Consumer Products - Disclosed are methods of solubilizing various coolants, in particular cyclohexane-based carboxamide derivatives to facilitate formulating these coolants into a wide variety of consumer products, including those for oral cavity, throat, skin and hair care applications. Suitable solvents are those that provide at least 5% concentrated solutions of these coolants. Particularly preferred solvents are those used in the perfume and flavor industries and are GRAS materials that do not contribute formulation difficulties or negative aesthetics. | 02-18-2010 |
20100040564 | BREATH FRESHENING AND ORAL CLEANSING PRODUCT WITH MAGNOLIA BARK EXTRACT IN COMBINATION WITH SURFACE ACTIVE AGENTS - An oral composition for oral cleansing, breath freshening, and anti-microbial benefits includes Magnolia Bark Extract in combination with a surface active agent. The effectiveness of Magnolia Bark Extract in inhibiting biofilm formation in the oral cavity is increased by a synergistic combination of the Magnolia Bark Extract with a surface active agent in an oral cavity delivery agent, such as chewing gum, a confectionary, a lozenge, a compressed tablet, and an edible film. | 02-18-2010 |
20100047190 | USES AND METHODS FOR PREVENTING AND/OR TREATING CARIES CAUSED BY MUTANTS STREPTOCOCCI - The present invention relates to the use of a microorganism belonging to the group of lactic acid bacteria or a mutant or derivative thereof, characterized in that it is capable of specifically binding to a bacterium belonging to the group of mutans Streptococci, wherein the specific binding is (i) resistant to heat treatment; and/or (ii) resistant to protease treatment; and/or (iii) calcium-dependent; and/or (iv) formed within a pH range between 4.5 and 8.5; and/or (v) formed in the presence of saliva, for the preparation of an anticariogenic composition for the treatment or prevention of caries caused by mutans Streptococci other than | 02-25-2010 |
20100055050 | NICOTINE CHEWING GUM ON A STICK - A device is disclosed for helping a smoker to quit smoking. The device includes a shaft with a mass of nicotine chewing gum cooperative with one end. A smoker controls the timing and quantity of nicotine delivered by controlling the amount of gum chewed and the duration of chewing. In some embodiments partially depleted gum can be replaced on the shaft for later use. A cover can be included to protect the gum when not in use. The cover can be a simple paper wrapper or a rigid cover with a mechanism to attach it to the shaft. Portion indicators can divide the gum into separately chewable portions. The shaft can be a simple stick, or a hollow tube containing a supply of gum for delivery as needed. Some hollow tube embodiments expel gum from the tube using a sliding mechanism or a twisting mechanism that functions like a lipstick. | 03-04-2010 |
20100055051 | MALODOUR COUNTERACTING COMPOSITION - A composition for counteracting malodour due to thiols, with the composition including a polyphenol, a source of polyphenol, a composition comprising polyphenol or mixtures thereof, a base, and optionally, an enzyme, wherein the polyphenol is encapsulated. The polyhenol is preferably a green tea extract and the enzyme is polyphenol (per)oxidase acetone powder. | 03-04-2010 |
20100061939 | Chewing Gum - Chewing gum comprising an extract from coffee enriched in at least one ester formed between a trans-cinnamic acid and quinic acid wherein the amount of said at least one ester in the gum is 0.1 to 50 wt %. | 03-11-2010 |
20100061940 | Chewing Gum Compositions Providing Rapid Release of Nicotine - Use of a nicotine-cellulose combination and a gum base for the preparation of a chewing gum composition for achieving a fast onset of nicotine effect after initiation of chewing the chewing gum composition by a subject. The chewing gum composition is preferably prepared by direct compression and it does not disintegrate during chewing. The invention also relates to chewing gum compositions comprising nicotine, which compositions provide a rapid release of nicotine. | 03-11-2010 |
20100061941 | TOOTH WHITENING COMPOSITIONS AND DELIVERY SYSTEMS THEREFOR - Stain-removing oral compositions, such as gum compositions are herein provided. The compositions include an orally acceptable carrier and a stain-removing anionic surfactant. The surfactant includes a fatty acid salt having at least one hydroxyl functionality. The fatty acid salt may be a salt of ricinoleic acid, and may be combined with a chelating agent and/or an abrasive. The chelating agent may be a polyphosphate and the abrasive may be a silica abrasive. | 03-11-2010 |
20100086495 | COMPOSITIONS AND METHODS FOR ENHANCING TRANSMUCOSAL DELIVERY - The present invention provides transmucosal pharmaceutical or nutraceutical compositions and methods for enhancing transmucosal delivery of pharmaceutical and nutraceutical ingredients through use of methylsulfonylmethane (MSM) as a transmucosal delivery enhancer. In particular, the invention provides transmucosal compositions comprising an active agent selected from a non-steroid anti-inflammatory drug (NSAID); an analgesic; a migraine medication; a menopause medication; a sleep disorder medication; an erectile dysfunction medication, an appetite suppressant, a vitamin, a food supplement and a macromolecule. In certain particular exemplary formulations the appetite suppressant is DL-phenylalanine, and the vitamin is B12. | 04-08-2010 |
20100086496 | ORAL CARE PACKAGE - An oral care package includes a package wrapping a tooth pick (or preferably a combined pick and flossing device) impressed within or adjacent to a stick of chewing gum in such manner that the pick (or pick/floss device) may be easily removed from the package first and used to dislodge matter from between the teeth and along the gums of the user prior to chewing the gum. | 04-08-2010 |
20100092406 | Systems, Methods, and Compositions for Treatment and Use of a Palatal Patch - Devices and methods for a palatal patch include a tablet or strip having a bioadhesive component and an active component. The bioadhesive component allows for the palatal patch to be attached to an upper palate, and for the active component to be released into the oral cavity and/or GI tract. Compositions for the active component include compositions for treatment of halitosis, anti-acids, vitamins, anti-smoking agents, and others. A composition for treatment of halitosis includes at least one of Echinacea, Lavender, Mastic Gum and Sage. A device for delivery of the palatal patch to the upper palate includes a housing and a piston, the piston having a holder for the palatal patch, and wherein the piston may be configured to move distally so as to delivery the palatal patch to the upper palate. | 04-15-2010 |
20100104518 | CHEWING GUM, CONFECTION, AND OTHER ORAL DELIVERY VEHICLES CONTAINING A TRADITIONAL CHINESE MEDICINE OR EXTRACT THEREOF - A method for producing a chewing gum with a controlled release traditional Chinese medicine active agent, as well as the chewing gum so produced, is obtained by physically modifying the release properties of the traditional Chinese medicine active agent by coating and drying. The traditional Chinese medicine active agent is coated by encapsulation, partially coated by agglomeration, entrapped by absorption, or treated by multiple steps of encapsulation, agglomeration, and absorption. The coated traditional Chinese medicine active agent is preferably then co-dried and particle sized to produce a release-modified traditional Chinese medicine active agent for use in chewing gum. The traditional Chinese medicine active agent may also be used in a coating on a chewing gum product, as part of a rolling compound applied to the chewing gum product, or as a part of the liquid in a liquid-center chewing gum product. | 04-29-2010 |
20100124537 | MEDICAL APPLICATIONS OF ALPHA-KETOGLUTARATE - The invention relates to a new use of alpha-ketoglutarate for manufacturing of medical preparation for prophylaxis or treatment of undesired medical conditions associated with the presence and/or activity of ureolytic bacteria in living organisms, except plants, including a human being, pet and farm animal, such as mammal, bird, amphibian, fish, molluse or arthropod, whereas the undesired medical conditions is a condition associated with the presence and/or activity in the gastrointestinal tract, respiratory and/or urogenital system of ureolytic bacteria from the group including | 05-20-2010 |
20100129295 | Compositions for preventing and/or treating gingivitis - Compositions and methods for preventing and/or treating gingivitis which include the use of one or a plurality of TNF-α modulators. | 05-27-2010 |
20100129296 | EXTRACT OF TRIGONELLA FOENUM-GRAECUM - Disclosed herein is an extract obtainable from | 05-27-2010 |
20100143270 | THERAPEUTIC COTININE COMPOSITIONS - The present invention provides methods and compositions for treating acute and/or chronic inflammation with cotinine or a pharmaceutically acceptable salt thereof. | 06-10-2010 |
20100158820 | XYLITOL DENTAL MAINTENANCE SYSTEM - A system, kit and method for promoting oral hygiene are disclosed. The kit may comprise several compositions or a single composition, each of which comprises an effective amount of xylitol. For example, the system and kit may comprise a chewing gum composition, a morsel composition, a paste-like composition, and an oral rinse composition; or any one of the above compositions; or any combination of the above compositions. It will be appreciated that a novel method for using such a system and kit for promoting oral hygiene may include: administering about 0.5 grams to about 2.0 grams of xylitol through the paste-like composition in the morning and in the evening, administering about 0.5 grams to about 2.0 grams of xylitol after consumption of nutrition through chewing the gum composition or through the morsel composition, and administering about 0.5 grams to about 1.5 grams of xylitol per application through the oral rinse composition. | 06-24-2010 |
20100202980 | Herbal Compositions for the Treatment of Diabetes and/or Conditions Associated Therewith - The present invention discloses herbal compositions comprising at least one | 08-12-2010 |
20100202981 | COMPOSITIONS HAVING IMPROVED SUBSTANTIVITY - The present invention relates to oral care compositions providing improved substantivity to and for the tissues and hard surfaces of the oral cavity. | 08-12-2010 |
20100209359 | MEDICATED CHEWING GUM - The present invention provides a chewing gum composition comprising a chewing gum base, a biologically active ingredient, a polymeric material and one or more sweetening and flavouring agents, wherein the polymeric material is amphiphilic, has a straight or branched chain carbon-carbon backbone and a multiplicity of side chains attached to the backbone. A method of making the chewing gum composition is also provided. | 08-19-2010 |
20100233100 | AMPHIPHILIC COPOLYMERIC MATERIAL - An amphiphilic polymeric material which has a straight or branched chain polymer backbone and a multiplicity of side chains attached to the backbone, wherein the backbone is a copolymer of at least one ethylenically-unsaturated aliphatic hydrocarbon monomer and maleic anhydride, or is a terpolymer of maleic anhydride, ethylene, and a further ethylenically unsaturated monomer. A method of synthesising said polymeric material is also provided, together with chewing gum bases, compositions and emulsions comprising amphiphilic polymeric materials. | 09-16-2010 |
20100247453 | COMPOSITION AND METHOD OF TREATING A SORE THROAT - A composition comprising an antacid, and a local, topical anesthetic. The composition is used to relieve pain or discomfort associated with a sore throat, and therefore, the invention is also directed to a method of alleviating the pain or discomfort associated with a sore throat comprising instructing a human to orally administer the composition. | 09-30-2010 |
20100260690 | STABLE CHEWING GUM COMPOSITIONS COMPRISING MALTITOL AND PROVIDING RAPID RELEASE OF NICOTINE - Use of a nicotine-cellulose combination, maltitol and a gum base for the preparation of a chewing gum composition for achieving a fast onset of nicotine effect after initiation of chewing the chewing gum composition by a subject. The chewing gum composition is preferably prepared by direct compression and it does not disintegrate during chewing. The invention also relates to chewing gum compositions comprising nicotine, which compositions provide a rapid release of nicotine. | 10-14-2010 |
20100266513 | AMPHIPHILIC POLYMERIC MATERIAL - The present invention concerns an amphiphilic polymeric material which comprises a straight or branched chain carbon-carbon backbone and a multiplicity of side chains attached to the backbone, wherein the side chains have formula (I). At least one of R | 10-21-2010 |
20100272655 | Menthylcarboxamides and Their Use as Cooling Agents - Described is a new cooling agent represented by Structure I and compositions with known coolers having cooling properties and the application of Structure I in foodstuffs and chewing gum: | 10-28-2010 |
20100284944 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS - Disclosed are Compounds that block off-notes in consumables and methods of blocking off-notes in consumables including off-notes provided by artificial sweeteners including aspartame, Saccharin, acesulfame K (Acesulfame potassium), sucralose and cyclamate; and including stevioside, swingle extract, glyccerhizin, perillartine, naringin dihydrochalcone, neohesperidine dihydrochalcone, mogroside V, rubusoside, rubus extract, and rebaudioside A. | 11-11-2010 |
20100284945 | FORMULATIONS FOR THE TREATMENT OF MUCOSITIS INDUCED BY ANTITUMOR OR IMMUNOSUPPRESSIVE THERAPY - Formulations containing sanguinarine or chelerythrine or the salts thereof or extracts containing them in admixture with suitable carriers and/or excipients for the treatment and/or prevention of mucositis. | 11-11-2010 |
20100284946 | Compressed Chewing Gum Comprising Sterol - A compressed chewing gum tablet including at least one chewing gum module, the chewing gum module including a chewing gum composition including chewing gum particles containing gum base, wherein the chewing gum tablet includes at least one sterol compound, and wherein at least a part of the at least one sterol compound is located outside the chewing gum particles containing gum base. | 11-11-2010 |
20100291004 | COMPOSITIONS FOR DELIVERING HYPNOTIC AGENTS ACROSS THE ORAL MUCOSA AND METHODS OF USE THEREOF - The present invention provides novel compositions for the delivery of a hypnotic agent across the oral mucosa. In particular, the buffer system in the compositions of the present invention raises the pH of saliva to a pH greater than about 7.8, thereby facilitating the substantially complete conversion of the hypnotic agent from its ionized to its un-ionized form. As a result, the dose of hypnotic agent is rapidly and efficiently absorbed by the oral mucosa with surprisingly low inter-subject variability. Furthermore, delivery of the hypnotic agent across the oral mucosa advantageously bypasses hepatic first pass metabolism of the drug and avoids enzymatic degradation of the drug within the gastrointestinal tract. Methods for using the compositions of the present invention for treating sleep disorders such as insomnia are also provided. | 11-18-2010 |
20100291005 | USE OF TRANS-PELLITORIN AS FLAVOR SUBSTANCE - The invention concerns the use of 2E,4E-decadienoic acid-N-isobutylamide (trans-pellitorin) as flavorant, in particular as salivation inducing flavor substance, preferably in a foodstuff or nutrient, an oral hygienic preparation or a gourmet or snack preparation. Further, the invention concerns preparations, semi-finished preparations as well as fragrance, aroma and taste compositions, containing trans-pelletorin as well as a processes for the production of trans-pelletorin. | 11-18-2010 |
20100297037 | MATERIAL COMPOSITION FOR ORAL HYGIENE PRODUCT - The present invention relates to a material composition, particularly for an oral hygiene product suitable for combating caries and also for combating parodontitis and gingivitis. Said material composition or oral hygiene product is characterized in that it comprises an extract of Curcuma xanthorrhiza or xanthorrhizol and folic acid. | 11-25-2010 |
20100297038 | Benzimidazole Derivatives And Their Use As Cooling Agents - The present invention refers to compounds with cooling properties, the compound are of formula (I), | 11-25-2010 |
20100303737 | Tooth-Cleaning Formulation - A tooth-cleaning formulation which contains Himalaya salt in an unadulterated and also non-heat-treated form and/or Sango coral, with the Himalaya salt being used as a direct natural raw material and not being heated and sterilized itself. | 12-02-2010 |
20100316578 | ORAL COMPOSITIONS FOR ABSORPTION OF PHOSPHOROUS COMPOUNDS - The present invention provides medicaments useful for reducing phosphorus serum level, especially in those subjects affected from hyperphosphatemia. More specifically, the present invention relates to pharmaceutical compositions to be administered by oral route in fasting periods, in order to absorb phosphorus compounds from fluids of the enteric tract, especially from saliva. | 12-16-2010 |
20100330000 | ENZYMES FOR TREATMENT OF GINGIVITIS - The invention relates to a method for treating, controlling and/or preventing diseases of the oral cavity, particularly diseases and disorders induced accumulation of plaque, by administering a chewing gum composition comprising at least one krill enzyme. Specifically, the invention is directed to a method for preventing, treating and controlling the development of gingivitis, gum disease and symptoms thereof using a composition having a krill enzyme concentration of about 0.005 U/g to about 0.05 U/g of the chewing gum composition. | 12-30-2010 |
20100330001 | ANTIBACTERIAL COMPOSITIONS - The present invention relates to oral antibacterial compositions comprising trihydroxybenzoate derivatives, e.g., useful for the treatment of gum diseases (e.g., gingivitis or periodontitis) and to methods of using such compositions. | 12-30-2010 |
20100330002 | COMPOSITIONS AND METHODS COMPRISING BASIC AMINO ACID PEPTIDES AND PROTEASES - The present invention is directed to compositions comprising peptides comprising a basic amino acid. e.g., arginine, and a protease. | 12-30-2010 |
20110002858 | ORAL COMPOSITIONS FOR ABSORPTION OF PHOSPHOROUS COMPOUNDS - The present invention provides medicaments useful for reducing phosphorus serum level, especially in those subjects affected from hyperphosphatemia. More specifically, the present invention relates to pharmaceutical compositions to be administered by oral route in fasting periods, in order to absorb phosphorus compounds from fluids of the enteric tract, especially from saliva. | 01-06-2011 |
20110002859 | CHEWING GUM CONTAINING EUCALYPTUS EXTRACT - It is an object of the present invention to provide a chewing gum, by which an effect of preventing periodontal disease is obtained through mastication without performance required for a chewing gum being impaired, such as taste, appearance, and physical properties and storage stability as a product. A chewing gum containing Eucalyptus extract of the present invention is characterized by containing at least one kind of macrocarpal A, macrocarpal B, and macrocarpal C, contents of the macrocarpal A, the macrocarpal B, and the macrocarpal C being 0.001 to 0.0045% by weight, 0.003 to 0.0045% by weight, and 0.0015 to 0.0045% by weight with respect to a total weight of the chewing gum, respectively. | 01-06-2011 |
20110020245 | FUNCTIONALIZED CALCIUM PHOSPHATE HYBRID SYSTEMS FOR CONFECTIONERY AND FOODSTUFF APPLICATIONS - A method for repairing dentition, including milling beta tricalcium phosphate with sufficiently high energy to substantially distressed its lattice structure, mechanochemically chelating an edible acid thereto to yield functionalized calcium phosphate moieties, and incorporating the functionalized calcium phosphate moieties into an edible material to yield a calcium phosphate delivery system. The calcium phosphate delivery system is introduced into an oral environment and dentition is repaired. The functionalized calcium phosphate moiety is characterized by weakly bonded fumaric acid at least partially wrapped around distressed calcium phosphate particles, and dentition repair occurs at a dentition depth of at least 10 microns below the surface. | 01-27-2011 |
20110033391 | Transferases and Oxidoreductases, Nucleic Acids Encoding them and methods for making and using them - This invention relates generally to enzymes, polynucleotides encoding the enzymes, the use of such polynucleotides and polypeptides and more specifically to enzymes having transferase activity, e.g., transaminase activity, e.g., d-amino-acid transferase activity, and/or oxidoreductase activity, e.g., dehydrogenase activity, e.g., damino-acid dehydrogenase activity, and/or catalyze the transfer of a chemical group, catalyze transamination, catalyze the reaction: D-alanine+2-oxoglutarate<=>pyruvate+D-glutamate, and/or catalyze an oxidation-reduction reaction, catalyze the removal of hydrogen atoms, and/or catalyze the reaction: D-amino acid+H | 02-10-2011 |
20110033392 | DEODORIZING COMPOSITION UNDER WEAK ACIDITY - The present invention provides a deodorizing composition containing as an active ingredient thereof a natural plant extract with high safety, which can be used for foods without any anxiety concerning safety in use and shows a high deodorizing effect even in a weakly acidic condition, and foods and drinks containing such a composition. The deodorizing composition comprises a plant of the genus | 02-10-2011 |
20110038808 | FLAVORED CHEWABLE FOAMS AND A PROCESS FOR THEIR PRODUCTION - Flavored chewable foams for the oral care sector are produced from a polyurethane-polyurea and a sensorially active substance (e.g., taste substance and/or aroma substance) by foaming a polyurethane-urea dispersion, drying that dispersion and incorporating the sensorially active substance into the polyurethane-urea dispersion before, during or after foaming of the dispersion. | 02-17-2011 |
20110044915 | CONFECTIONERY CONTAINING ALGAE FOR THE PREVENTION OF ORO-DENTAL INFECTIONS - The present invention relates in general to a sweet. More specifically, the present invention relates to a sweet which provides beneficial effects on the teeth. The sweet according to the present invention promotes good oro-dental hygiene, and more particularly provides oro-dental care, and promotes and maintains healthy teeth and gums. It is characterized in that it contains microalgae and/or extracts of microalgae, and more particularly | 02-24-2011 |
20110070170 | MANUFACTURE OF CHEWING GUM PRODUCT WITH RADIOFREQUENCY - The present invention features a process for making a chewing gum product including the steps of forming a powder blend containing a gum base into the desired shape of the chewing gum product and applying radiofrequency energy to the shape for a sufficient period of time to soften the gum base to fuse the shape into the chewing gum product. | 03-24-2011 |
20110081303 | TEETH CLEANING COMPOUND CONTAINING MENTHOL WITH REDUCED BITTER SENSATION - The present invention primarily concerns teeth cleaning compounds containing menthol for use with a toothbrush, preferably tooth pastes, tooth crèmes, tooth cleaning gels or tooth powders. Such a tooth cleaning compound according to the invention contains menthol and a quantity, for masking the bitterness of the menthol, of menthane carboxylic acid-N-(4-methoxyphenyl)-amide (WS-12) of the following formula (Ia), in particular of the following formula (Ib), i.e. L-menthane carboxylic acid-N-(4-methoxyphenyl)-amide. | 04-07-2011 |
20110091391 | DISCRETE TUNABLE SENSING ELEMENTS AND COMPOSITIONS FOR MEASURING AND REPORTING STATUS AND/OR PRODUCT PERFORMANCE - Discrete sensing elements are described that can be integrated into dental hygiene products and can provide rapid and direct feedback to a user as to oral environmental status and as to the performance of the intended oral care product. Selectively tuned elements can both sense and report relevant information including usage time, adequacy of performance during use, training for better usage, and/or the physical or biological status as can be measured by direct oral contact. Sensing and reporting mechanisms can be tuned for increased or decreased sensitivities. Sensing elements can comprise one or more discrete optical changes, structural changes, or other physical changes to the dental hygiene product as a means of alerting a user of a stimulus. Use of optical reference colors provides a high level of accuracy and objectivity as to the status of a sensing event. Enabling delivery and application compositions and methods are described. | 04-21-2011 |
20110091392 | COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF INFECTIONS OF THE ORAL CAVITY - The present invention relates to compositions comprising benzophenanthridine alkaloids, benzofuran compounds and catechin polyphenols, which are useful in the treatment and prevention of infections of the oral cavity. | 04-21-2011 |
20110097283 | CHEWING GUM COMPOSITIONS COMPRISING CANNABINOIDS - The present invention relates to a chewing gum composition comprising 0.01 to 15% by weight a cannabinoid or a derivative thereof, based on the total weight of the chewing gum composition, and to chewing gums and blistering packages comprising said chewing gums. | 04-28-2011 |
20110097284 | USE AND METHODS FOR PREVENTING AND/OR TREATING ORAL MALODOUR - Described is a microorganism belonging to the group of lactic acid bacteria which is able to drastically reduce the peptide concentration in saliva thereby depleting the substrate used by anaerobic microorganisms of the oral micro-flora which are the causative agent for oral malodour. Moreover, described is a microorganism belonging to the group of lactic acid bacteria which is able to stimulate the growth of | 04-28-2011 |
20110117031 | METHOD FOR TREATING HYPERSENSITIVE TEETH - A method for imparting a teeth-desensitising effect to a food, cosmetic or pharmaceutical which comprises combining said food, cosmetic or pharmaceutical with a teeth-desensitising effective amount of a polyol. | 05-19-2011 |
20110123461 | Compositions and Methods for the Maintenance of Oral Health - The invention provides compositions comprising one or more isolated LDH-deficient | 05-26-2011 |
20110129426 | ORAL COMPOSITIONS CONTAINING ENHANCED ANTIBACTERIAL COMBINATIONS OF ANTIOXIDANTS AND EXTRACTS OF MAGNOLIA - An oral composition contains an enhanced antibacterial effective amount of an antioxidant and an extract of Magnolia. | 06-02-2011 |
20110142768 | CALCIUM PEROXYPHOSPHATES AND USE THEREOF IN DENTAL COMPOSITIONS - Calcium peroxyphosphate compounds and dental compositions comprising these compounds that combine both whitening/stain removal of teeth with remineralization are disclosed. The calcium peroxyphosphate compounds are capable of releasing, in an aqueous environment, whitening and remineralization effective amounts of calcium ion, phosphate ion, and active oxygen. Preferred compounds are calcium peroxymonophosphate or calcium diperoxymonophosphate compounds. These compounds may be used in humans and other animals, including other mammals. | 06-16-2011 |
20110177012 | MONO-, DI- AND POLYOL ALKOXYLATE PHOSPHATE ESTERS IN ORAL CARE FORMULATIONS AND METHODS FOR USING SAME - This invention relates to a composition useful as an oral care composition comprising an organophosphate material, additional oral care composition ingredients, for example, a surfactant agent, and optionally an abrasive agent. | 07-21-2011 |
20110189107 | ALPHA-AMYLASE INHIBITORS: THE MONTBRETINS AND USES THEREOF - Particular naturally occurring glycosylated acyl-flavonols, e.g. montbretin A (of the formula below wherein R | 08-04-2011 |
20110236322 | ORAL PH AND BUFFERING CAPACITY MODIFIERS - Example embodiments of the present invention include various compositions that include a pH modifier composition and/or a buffering capacity modifier composition. In some examples, the pH modifier compositions include a dose of pH modifier to raise the pH in a patient's mouth from about 1 to about 2 pH levels. The compositions are then incorporated into various confections for oral ingestion or application that allow a patient to easily use the composition with the pH and/or buffering capacity modifiers. For example, compositions with the pH and/or buffering capacity modifiers can be incorporated within chewing gum, tablets, lozenges, breath strips, hard candy, oral sprays, and other confections. Another embodiment of the invention includes a testing device to test the pH and buffering capacity within a patient's mouth. | 09-29-2011 |
20110250150 | Multi-Part Kit Comprising A Chewing Gum And Further A Flavor Containing Formulation - A multi-part kit for administering at least one active pharmaceutical ingredient including at least one piece of chewing gum including the active pharmaceutical ingredient, the piece of chewing gum comprising gum base; and at least one further flavor-containing formulation; wherein the gum base content of the at least one further flavor-containing formulation is less than 70% by weight of the gum base content of said piece of chewing gum. | 10-13-2011 |
20110256071 | THIOL-CONTAINING FRAGRANCE AND FLAVOR MATERIALS - One aspect of the present invention provides a compound represented by formula (I), | 10-20-2011 |
20110256072 | FOOD AND COMPOSITION EACH COMPRISING PHOSPHORYLATED SACCHARIDE, POLYPHENOL AND FLUORIDE - A cariostatic food is provided. The food comprises: (1) (i) a phosphorylated saccharide calcium salt; or (ii) a combination of a phosphorylated saccharide salt other than a phosphorylated saccharide calcium salt or a phosphorylated saccharide, and a water-soluble calcium salt other than a phosphorylated saccharide calcium salt; (2) a fluoride; and (3) a polyphenol; wherein the phosphorylated saccharide is composed of a saccharide moiety and phosphate group(s); the content of the component (1) in the food is in an amount suitable to make the calcium concentration in saliva in the oral cavity to be 1 mM to 12 mM when the food exists in the oral cavity; and the content of fluoride in the food is in an amount suitable to make the fluoride concentration in saliva in the oral cavity to be 0.2 ppm to 100 ppm when the food exists in the oral cavity. | 10-20-2011 |
20110268669 | COMPOSITION AND METHOD FOR TREATING EUSTACHIAN TUBE DYSFUNCTION - A method of treating Eustachian tube dysfunction in a person includes placing the person's body in a position substantially lying on one of the person's left or right sides. The side on which the person is lying is the side affected by Eustachian tube dysfunction. A composition of simethicone in a concentration of about 0.05% to 0.65% wt/vol diluted in an aqueous carrier is introduced through the nasal cavity of the same side on which the person is lying. The simethicone composition is then allowed to coat the person's pharynx on the side of which the person is lying. | 11-03-2011 |
20110274628 | NICOTINE-CONTAINING PHARMACEUTICAL COMPOSITIONS - A composition intended to be employed for therapeutic purposes incorporates nicotine and at least one other nicotinic compound. Representative forms of nicotine can be as a free base (e.g., as a mixture of nicotine and microcrystalline cellulose), as a form of nicotine salt (e.g., as nicotine bitartrate) or as nicotine polacrilex. The other nicotinic compound is a compound that can be considered to bind selectively to certain nicotinic receptor subtypes, and particularly those of the central nervous system. For example, the other nicotinic compound can be a compound that binds selectively to the nicotinic receptor subtypes α | 11-10-2011 |
20110280812 | FLAVOR-ENHANCING AMIDE COMPOUNDS - The present invention has discovered that amide compounds represented by Formula I set forth below have unexpected and advantageous flavor enhancement and modification properties: | 11-17-2011 |
20110286941 | COMBINATION OF TWO MATERIAL COMPOSITIONS FOR AN ORAL HYGIENE PRODUCT - The present application relates to a combination of two separately stored and jointly used compositions, which are suitable for the combat and the prevention of caries. Thereby, each of the two compositions respectively comprises a fluorine compound. Further, one composition comprises an acidic pH-value, while the other composition comprises a basic pH-value. | 11-24-2011 |
20110293537 | FORMULATIONS WITH ANTI-NEOPLASTIC ACTIVITY - Pharmaceutical formulation comprising at least one aryl hydrocarbon receptor ligand and at least one cyclodextrin for the prevention and/or treatment of carcinomas, preferably squamous cell carcinomas, more preferably oral squamous cell carcinomas. | 12-01-2011 |
20110318279 | POLYMERIC MASTICATORY MASSES FOR COSMETIC PRODUCTS - The invention relates to novel masticatory masses for oral hygiene, made from foamed synthetic polymers, a method for production and use thereof. | 12-29-2011 |
20120009131 | METHOD FOR PREVENTING OR TREATING AMYLOID BETA PEPTIDE-ASSOCIATED DISEASES OR CONDITIONS, AND METHOD FOR INHIBITING FORMATION, ACCUMULATION OR AGGREGATION OF AMYLOID BETA PEPTIDES - Isoacteoside or a pharmaceutically acceptable salt thereof is used to prevent or treat amyloid beta peptide-associated diseases or conditions as an agent for inhibiting formation, accumulation or aggregation of amyloid beta peptides. | 01-12-2012 |
20120027693 | METHODS AND COMPOSITIONS FOR PREVENTING AND RELIEVING MUSCLE CRAMPS AND FOR RECOVERY FROM NEUROMUSCULAR IRRITABILITY AND FATIGUE FOLLOWING EXERCISE - The methods and compositions of the present invention are directed to the treatment or amelioration of muscle cramps using a composition that includes one or more TRPV1 channel activators, and/or one or more TRPA1 channel activators, and/or one or more ASIC channel activators. | 02-02-2012 |
20120027694 | INDUCIBLE RELEASE VEHICLES - This invention relates to inducible release vehicle comprised of crosslinked carbohydrates or proteins and an active ingredient. The release is induced by an external stimulus, e.g. an enzyme such as amylase. Such a vehicle can particularly be used in an applications for preventing microbial decay or combating microbial infections. Other uses are for oral applications such as providing anti-caries or flavoring compounds and for pharmaceutical and/or nutraceutical applications. | 02-02-2012 |
20120045400 | ORAL COMPOSITIONS CONTAINING POLYGUANIDINIUM COMPOUNDS AND METHODS OF MANUFACTURE AND USE THEREOF - The invention describes the modification of polyamine-based materials to form polyguanidine compounds that are useful for their antimicrobial, anticaries, and muccoadhesive properties. The present invention also relates to methods for preventing or treating periodontal disease and caries which include delivering a therapeutically effective amount of an oral composition containing a polyguanidine compound into an oral cavity. | 02-23-2012 |
20120064015 | Food Additive Composition as an Agent for Reducing the Adhesion of Dental Biofilms in Sweetened Products - The present invention relates to a food additive composition to be added to sugar or sweetened products containing cariogenic free sugars or by-products thereof, enabling a reduction of the adhesion of dental biofilms and the appearance of caries while strengthening the tooth and the dental support tissue. The present invention also relates to food products made of cariogenic free sugars or by-products thereof containing said food additive product, as well as to a method of manufacturing such a food product containing said food additive composition, such as a chocolate. | 03-15-2012 |
20120087874 | WARMING COMPOSITIONS AND DELIVERY SYSTEMS THEREFOR - The present invention includes compositions for imparting a controlled-release warming sensation to the oral receptor areas of a user. The oral, controlled-release warming compositions include a warming agent and a hydrated or swollen food-grade polymer which forms a matrix with the warming agent. Also included are oral delivery systems for the warming compositions, methods for preparing same, and methods for imparting and sustaining a warming sensation in the mouth and upper portion of the gastrointestinal tract of the user. | 04-12-2012 |
20120087875 | Buffered Gum Base For High PH Release - A chewing gum composition with high pH-release includes an insoluble gum base matrix and a soluble bulk portion, wherein the gum base matrix and the bulk portion is mixed and extruded to form a final chewing gum core, and wherein the gum base matrix is buffered before mixing with the bulk portion. Furthermore, a method of producing a chewing gum core, wherein a gum base matrix and a bulk portion is mixed and extruded to form a final chewing gum core, and wherein the gum base matrix is buffered before mixing with the bulk portion, and the gum base matrix includes a first amount of buffer from 2 to 20 percent by weight of the gum base matrix before mixing with the bulk portion. | 04-12-2012 |
20120100082 | ORAL COMPOSITION - Provided is an oral composition having a tongue coating removing effect and a strong bad breath removing effect. An oral composition having a tongue coating removing action, characterized by containing an extract of | 04-26-2012 |
20120114566 | LIPOXIN ANALOGS AND METHODS FOR THE TREATMENT OF PERIODONTAL DISEASE - This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease. The invention also provides for methods of treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease with compositions containing COX-2 inhibitors. Further, the invention provides methods for preventing systemic diseases beyond theoral cavity that are related to periodontal disease using the composition containing lipoxin analogs, COX-2 inhibitors, or both. | 05-10-2012 |
20120121520 | FUNCTIONAL FORMULATION IN CHEWING GUM - Nutraceutical gum or functional food compositions comprise Ashwagandha ( | 05-17-2012 |
20120128599 | ORAL CARE COMPOSITION - Disclosed are oral care compositions and the use of such oral care compositions for treating conditions caused by biofilm formation. Also disclosed are methods for inhibiting biofilm formation and/or degrading biofilm. The oral care composition includes a sesquiterpenoid and an antimicrobial agent, in which the sesquiterpenoid and the antimicrobial agent are present in an amount effective to inhibit and/or degrade a biofilm in the oral cavity. | 05-24-2012 |
20120141386 | Application of Antimicrobial and Glycemic Control Activities of Lo Han Kuo Fruit (Siraitia grosvenorii) - The present invention discloses an application of the extract of Lo Han Kuo (LHK) fruit ( | 06-07-2012 |
20120141387 | COMPOSITION INCLUDING AN UNSAPONIFIABLE FRACTION - The present invention relates to a composition, notably cosmetic, nutraceutical, dermatological, pharmaceutical or dietary, including at least one unsaponif iable extract, a drug including one such composition, the use of one such composition, a treatment method consisting in administering one such composition and a method comprising the administration of one such composition. | 06-07-2012 |
20120171128 | DENTAL CLEANING COMPOSITION - Provided are dental cleaning compositions, methods of using and methods of using such compositions which minimize gum damage in the oral cavity. In one form, the dental cleaning composition includes a substantially stoichiometric ratio of one or more oxidizing agents to one or more reducing agents in one or more one or more orally acceptable carriers; where the substantially stoichiometric ratio of one or more oxidizing agents to one or more reducing agents is sufficient to neutralize the oxidizing agent in a subject oral cavity; and where the one or more oxidizing agents and one or more reducing agents are either co-dispensed or sequentially dispensed in the subject oral cavity. | 07-05-2012 |
20120171129 | Inhibition and Dispersion of Bacterial Biofilms with Benzimidazole Derivatives - Disclosure is provided for benzimidazole derivative compounds that prevent, remove and/or inhibit the formation of biofilms, compositions including these compounds, devices including these compounds, and methods of using the same. | 07-05-2012 |
20120189558 | ANTI-BACTERIAL COMPOSITIONS COMPRISING EXTRACTS OF EREMOPHILA LONGIFOLIA AND METHODS FOR USE OF SAME - A method for inhibiting growth of bacteria is provided wherein the method comprises the step of administering to a region in need of bacterial growth inhibition an anti-bacterially effective amount of a composition comprising an extract from the plant | 07-26-2012 |
20120201762 | ORAL CARE COMPOSITION - Disclosed are oral care compositions and the use of such oral care compositions for treating or preventing oral malodor. Also disclosed are methods for treatment or prevention of oral malodor. The oral care compositions include serine in an amount effective to reduce oral malodor caused by hydrogen sulfide and/or indole. | 08-09-2012 |
20120213713 | Compositions of omega fatty acids for the prevention and treatment of dental caries resulting from oral infections - The present invention discloses compositions of omega polyunsaturated fatty acids for controlling and preventing dental caries resulting from oral infections. The compositions of fatty acids include omega-3 fatty acids, omega-6 fatty acids, and other fatty acids, for their synergistic bioactivity against cariogenic pathogens. The application of this composition can be used for the preparation of drugs, nutritional supplements, food and daily necessities with oral health care and therapeutic effects. | 08-23-2012 |
20120219510 | NATURAL EXTRACT FROM WHOLE BANANA FRUIT (MUSA SPP) - A natural Extract from whole Fruit of Banana ( | 08-30-2012 |
20120237454 | Means and Methods for Preventing and/or Treating Caries - The present invention relates to a microorganism belonging to the group of lactic acid bacteria capable of specifically binding to | 09-20-2012 |
20120237455 | ORAL COMPOSITIONS CONTAINING EXTRACTS OF ZIZYPHUS JOAZEIRO AND RELATED METHODS - Described herein are compositions comprising a combination of extracts, and methods of preparing and using the same. | 09-20-2012 |
20120237456 | ORAL COMPOSITIONS CONTAINING EXTRACTS OF GARCINIA MANGOSTANA L. AND RELATED METHODS - Described herein are compositions comprising a combination of extracts, and methods of preparing and using the same. | 09-20-2012 |
20120244084 | HERBAL EXTRACTS AND FLAVOR SYSTEMS FOR ORAL PRODUCTS AND METHODS OF MAKING THE SAME - The invention provides a method for preparing an herbal extract and a flavor system comprising an herbal extract produced by the process. The invention also provides a flavor system comprising an herbal extract comprising thymol, eugenol, carvacrol and eucalyptol. The invention further provides a flavor system comprising a thyme extract having a minimum inhibitory concentration of less than about 3%. Additionally, the invention provides an oral product comprising a flavor system. | 09-27-2012 |
20120244085 | ORAL COMPOSITIONS CONTAINING EXTRACTS OF MYRISTICA FRAGRANS AND RELATED METHODS - Described herein are compositions comprising a combination of extracts, and methods of preparing and using the same. | 09-27-2012 |
20120244086 | ORAL COMPOSITIONS CONTAINING EXTRACTS OF ZINGIBER OFFICINALE AND RELATED METHODS - Described herein are compositions comprising a combination of extracts, and methods of preparing and using the same. | 09-27-2012 |
20120244087 | ORAL COMPOSITIONS CONTAINING A COMBINATION OF NATURAL EXTRACTS AND RELATED METHODS - Described herein are compositions comprising a combination of extracts comprising a mixture of extracts from at least three of | 09-27-2012 |
20120251461 | [((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexanecarbonyl)-amino]-acetic acid isopropyl ester and related compounds and their use in therapy - The present invention pertains generally to the field of coolants and medical therapy. More particularly, the present invention relates to certain anti-nociceptive agents, such as [((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexanecarbonyl)-amino]-acetic acid isopropyl ester, that are potent and long-acting and selectively cooling for non-keratinized epithelial tissues as compared to keratinized epithelial tissues, and are useful, for example, for the treatment of (e.g., the alleviation of symptoms of; the amelioration of) sensory discomfort of non-keratinized stratified epithelial (NKSE) tissue; and so for treatment of: sensory discomfort of an ocular surface, an eyelid, a margin of an eyelid, an anterior part of an eyeball, a conjunctiva, a lachrymal system, a pre-corneal film, or a cornea, a lining of the oral cavity, an internal portion of the lips, a pharyngeal surface, an esophageal surface, or an anogenital surface; eye discomfort, e.g., caused by extended wear of contact lenses, by eye strain and/or fatigue, by air pollutants, by excessive exposure to the sun, by conjunctivitis, by dry eye syndrome; sensory discomfort associated with oral mucositis; airway (e.g., larynx, trachea, and/or bronchi) tightness, discomfort in the airways (e.g., larynx, trachea, and/or bronchi), choking, cough, and/or dyspnea, e.g., associated with asthma and/or chronic obstructive pulmonary diseases (COPD). | 10-04-2012 |
20120251462 | Agent For Smoker Dehabituation - The present invention relates to rosmarinic acid for use in a method for smoker dehabituation, wherein the rosmarinic acid is preferably in the form of a dried, aqueous extract of leaves of lemon balm (Melissa officinalis). In addition, the present invention relates to foods and food supplements for use in a method for smoker dehabituation, wherein these foods and food supplements contain rosmarinic acid, in particular rosmarinic acid in the form of a dried, aqueous extract of leaves of lemon balm (Melissa officinalis). | 10-04-2012 |
20120251463 | Nicotinamide Riboside Kinase Compositions and Methods for Using the Same - The present invention relates to isolated nicotinamide riboside kinase (Nrk) nucleic acid sequences, vectors and cultured cells containing the same, and Nrk polypeptides encoded thereby. Methods for identifying individuals or tumors susceptible to nicotinamide riboside-related prodrug treatment and methods for treating cancer by administering an Nrk nucleic acid sequence or polypeptide in combination with a nicotinamide riboside-related prodrug are also provided. The present invention further provides screening methods for isolating a nicotinamide riboside-related prodrug and identifying a natural source of nicotinamide riboside. | 10-04-2012 |
20120251464 | CHALCONES AS ENHANCER OF ANTIMICROBIAL AGENTS - Compounds are described that are effective in enhancing the efficacy of antimicrobial agents. Also described are methods of using such compounds and compositions that include such compounds. The composition includes a chalcone compound and, optionally, an antimicrobial agent. | 10-04-2012 |
20120276020 | SUPERCRITICAL CO2 LIQUORICE EXTRACT ANTI-MICROBIAL AND ANTI-INFLAMMATORY ISOLATES AND PRODUCTS MADE THERE FROM - Described herein, are compositions comprising, inter alia, a supercritical CO | 11-01-2012 |
20120282191 | ORALLY DISPERSIBLE TABLET - The present invention provides a preparation with improved disintegration property, a preparation showing improved bioavailability of a medicament, production methods thereof and the like. A rapidly disintegrating preparation comprising granules comprising a medicament coated with a coating layer containing sugar or sugar alcohol; and a disintegrant. A production method of a rapidly disintegrating preparation including a step of producing granules comprising a medicament, a step of forming a coating layer containing sugar or sugar alcohol on the obtained granules and a step of mixing the coated granules with a disintegrant and molding the mixture. | 11-08-2012 |
20120288450 | Chewing gum formula for enhancing psycho-spirituality - The present invention relates to a chewing gum formulation that serves as a means for awakening human consciousness and mindfulness to the sensorial subtleties, which in turn strengthens sovereignty such that overall psycho-spirituality is enhanced. More particularly, this invention relates to a dietary supplement consisting of the botanical plant | 11-15-2012 |
20120288451 | MEANS FOR REMOVING TOBACCO TARS AND COMPOSITION CONTAINING SAME - The invention relates to cosmetology, specifically to tobacco tar removal agents based on terpenes and terpenoids, and compositions for oral cavity hygiene based on the use of such agents, including toothpastes and other products. The invention renders possible effective tobacco tar removal. The tobacco tar removal agent comprises at least one carbon dioxide plant extract with terpene and/or terpenoid content in the extract of min. 10 mass %. Also oral care compositions are disclosed comprising the above-mentioned tobacco tar removal agent. | 11-15-2012 |
20120321566 | INHIBITION OF BIOFILM FORMATION BY 1,2,3,4,6-PENTA-O-GALLOYL-D-GLUCOPYRANOSE - Disclosed herein are an anti-biofilm composition and a method to inhibit or prevent cell adhesion and/or biofilm formation by a microorganism, in which use of 1,2,3,4,6-penta-O-galloyl-D-glucopyranose (PGG) is involved therein. | 12-20-2012 |
20120328533 | HYPNOTIC COMPOSITIONS AND METHODS OF USE THEREOF - The present invention provides a chewing gum for treatment of sleep apnea. The chewing gum includes indiplon or a pharmaceutically acceptable salt thereof, a gum base, a protecting agent, a carbonate salt, a citrate salt, and a borate salt. The present invention also includes methods of treating narcolepsy, which include the step of administering a dosage form to a patient suffering from narcolepsy. The dosage form includes zopeclon or a pharmaceutically acceptable salt thereof, a bicarbonate salt, a metal oxide, and a phosphate salt. The dosage form could be a lyophilized powder or a chewing gum. | 12-27-2012 |
20130011343 | CHEWING GUM HAVING SUSTAINED RELEASE OF NICOTINE - The present invention relates to a chewing gum having a high Surface Area to Volume ratio (SAV ratio), wherein said chewing gum comprises a water insoluble gum base matrix, a water soluble bulk portion and nicotine, wherein the gum base matrix, nicotine and the bulk portion are mixed and extruded to form a final extruded chewing gum product having a SAV ratio above 0.7, and wherein sustained release of nicotine is facilitated by adding 0.1-10% of C8-C10 triglycerides by weight of the chewing gum. | 01-10-2013 |
20130011344 | USE OF IMINOCYCLITOLS AS INHIBITORS OF BACTERIAL ADHERENCE TO EPITHELIAL CELLS - It comprises the use of D-fagomine or derivatives thereof in the prevention and/or coadjuvant treatment of bacterial infections, as well as to pharmaceutical, veterinary, or food and feed, pet food compositions containing them. | 01-10-2013 |
20130022553 | NOVEL POLYAMINO POLYKETIDE ANTIBIOTICS AND USES THEREOF - The present invention relates to novel polyamino polyketide antibiotics, methods of their production as well as methods of using these antibiotics, for example, for inhibition or removal of biofilm formation or for treating bacterial infection with these antibiotics. | 01-24-2013 |
20130034506 | Water-Soluble Surfactant Compositions Having Improved Taste - Treated surfactant composition containing a water-soluble surfactant and exhibiting improved taste, said composition comprising: a water-soluble surfactant selected from alkyl phosphate surfactants, alkyl phosphate ethoxylated surfactants, betaine surfactants, betaine ethoxylated surfactants, amine oxide surfactants, and mixtures thereof and water; wherein the composition further comprises: less than about 4%, by weight of the water-soluble surfactant, of total undesirable non-polar materials; less than about 2.5%, by weight of the water-soluble surfactant, of alcohols having a carbon chain length of greater than 4; less than about 1%, by weight of the water-soluble surfactant, of amine and amide materials; and less than about 1%, by weight of the water-soluble surfactant, undesirable non-polar materials selected from aldehydes, esters, ketones, and organic acids. Such compositions wherein the compositions have been subjected to liquid-liquid extraction processes. | 02-07-2013 |
20130039864 | Non-Intravenous Dosage Form Comprising Solid Formulation of Liquid Biologically Active Agent and Uses Thereof - The disclosure relates to a non-intravenous dosage for administration of a liquid biologically active agent. The dosage form contains a solid formulation of the liquid biologically active agent, e.g. propofol, in intimate association with at least one stabilizing agent, e.g. an amphiphilic polymer or surfactant. A liquid biologically active agent is converted to a solid product, e.g. a powder, that can be easily incorporated into a number of different non-intravenous dosage forms. Upon hydration, a nanodispersion or micelle loaded with the active agent is formed. The dosage form can provide a non-intravenous route of administration for active agents that are typically only administered intravenously. Methods, uses, kits and commercial packages related to the non-intravenous dosage form are also disclosed. | 02-14-2013 |
20130045170 | IMMUNITY BOOSTING GUM - A chewing gum is disclosed with immunity boosting properties to ward off illness and promote favorable health. The chewing gum begins with a gum base, to which various medicinal elements are added so that they can be released during mastication of the gum. The medicinal elements include zinc, Vitamin C, elderberry, | 02-21-2013 |
20130058877 | Calculus dissolution compositions and methods for using same - The present invention relates generally to an anti-calculus composition and method for treating subgingival calculus. The anti-calculus composition comprises a pyrophosphate and a tripolyphosphate in a pharmaceutically acceptable carrier. The composition may also comprise a fluoride providing compound. | 03-07-2013 |
20130071338 | FORMULATION COMPRISING NICOTINE AND A CATION EXCHANGE RESIN - A method of producing a nicotine delivery product includes a mixture having nicotine, a cation exchange resin and water. The water content of the mixture is between 5 and 75 wt. % relative to the whole mixture. The mixture is combined with further components of the nicotine delivery product. | 03-21-2013 |
20130101527 | METHODS, COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING NEUROLOGICAL DISORDERS - Pharmaceutical compositions or formulations containing octanol are provided. The pharmaceutical compositions are useful for the prevention and treatment of a variety of conditions in mammals including humans, including neurological disorders such as thalamocortical dysrhythmia disorder. | 04-25-2013 |
20130108558 | FORMULATION COMPRISING NICOTINE AND A CATION EXCHANGE RESIN | 05-02-2013 |
20130115174 | TRANSMUCOSAL COMPOSITION CONTAINING ANTHOCYANINS FOR ALLEVIATING A VISUAL DISCOMFORT - The present invention relates to a composition comprising a natural extract containing anthocyanins and an agent for enhancing vigilance, and to a method for alleviating visual discomfort related to or caused by oxidative stress comprising administering via transmucosal route the composition of the invention, said composition being in a form adapted to transmucosal administration, said form preferably being a chewing gum, an orodispersible/orodisintegrating tablet or film or a buccal spray. | 05-09-2013 |
20130121931 | METHOD FOR CONTROLLING CONTINUOUSNESS OF DEODORANT EFFECT AFTER CONSUMPTION OF CHEWING GUM COMPOSITION AND A CHEWING GUM COMPOSITION - An object of the present invention is to provide a method for controlling the continuousness of deodorant effect after consumption of a chewing gum composition, and a chewing gum composition having excellent continuousness of the deodorant effect after consumption of the chewing gum composition. The method for controlling continuousness of the deodorant effect after consumption of the chewing gum composition, in which the chewing gum composition contains a biphenyl compounds-containing extract and a tannins-containing extract, includes the step of controlling the ratio of a blending amount of the tannins-containing extract to a blending amount of biphenyl compounds-containing extract. The chewing gum composition contains a biphenyl compounds-containing extract and a tannins-containing extract, in which the ratio by mass of the blending amount of the tannins-containing extract to the blending amount of the biphenyl compounds-containing extract is greater than 5.0. | 05-16-2013 |
20130129640 | Compressed Chewing Gum - A compressed chewing gum tablet including a chewing gum center, the gum center including a compression of gum base granules and chewing gum additives. The chewing gum additives include sweeteners and flavors. At least a first part of the gum base granules have granules of flavor incorporated gum base and at least a second part of the gum base granules have granules of conventional gum base. | 05-23-2013 |
20130136703 | LIMITED RELEASE LINGUAL THIOCTIC ACID DELIVERY SYSTEMS - A diffusion rate limiting matrix is utilized to lingually and/or sublingually deliver thioctic acid. This limited release matrix is intended for general nutritional supplementation and/or the treatment of various physiological disorders. Due to its lingual nature, this rate limiting matrix can produce IV-equivalent plasma levels and is not meant to be swallowed. | 05-30-2013 |
20130149254 | CHEWABLE POUCH FOR FLAVORED PRODUCT DELIVERY - Provided is a disintegrable or non-disintegrable oral flavor delivery product. The product includes a disintegrable or non-disintegrable chewable pouch with a plurality of perforations. The pouch encloses a non-tobacco flavor product that can be in a gel, semi-liquid, and/or liquid form. A user chews, sucks, and/or manipulates the pouch to cause the enclosed flavor product to leach out of the perforations into the user's mouth. | 06-13-2013 |
20130149255 | VITAMIN B12 COMPOSITIONS - This disclosure provides compositions of vitamin B | 06-13-2013 |
20130171077 | ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF - Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia. | 07-04-2013 |
20130177506 | Bio-Available Chlorogenic Acid Preparations for Supplemental Human Consumption and Use - A chewing gum, creamer, powdered supplement or other confection, as a food supplement formulated to combine natural or artificial sweeteners and flavorings with CGA, packaged for retail sale to consumers, for providing an ideal bio-available delivery mode for CGA, a recognized antioxidant and natural metabolic stimulant, as a ready supplement for bioactive immune support and to aid users in management of weight loss, obesity and/or glucose management, or for general health and well-being of users. | 07-11-2013 |
20130183252 | COMPOUNDS THAT INHIBIT (BLOCK) BITTER TASTE IN COMPOSITION AND METHODS OF MAKING SAME - The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds present in, e.g., coffee. Also, the invention relates to the discovery of specific compounds and compositions containing that function as bitter taste blockers and the use thereof as bitter taste blockers or flavor modulators in, e.g., coffee and coffee flavored foods, beverages and medicaments. Also, the present invention relates to the discovery of a compound that antagonizes numerous different human T2Rs and the use thereof in assays and as a bitter taste blocker in compositions for ingestion by humans and animals. | 07-18-2013 |
20130195770 | COMPOSITION AND METHOD FOR REDUCING ATHEROSCLEROTIC LESIONS - The present invention relates to a method for reducing cholesterol absorption and the occurrence of atherosclerotic lesions in an animal comprising administering to the animal a composition comprising an effective amount of at least one cholesterol ester. | 08-01-2013 |
20130209373 | TUBE FEED PACKAGES AND METHODS FOR USING SAME - Nutritional compositions that mimic whole foods and methods of using the nutritional compositions are provided. The nutritional compositions may include an increased number and variety of fruits and vegetables, an increased variety of macronutrient sources and an increased amount of other components that are found in whole foods. The nutritional compositions may also include ethnicity-specific meals and organic ingredients and provide emotional appeal to the patient and/or the patient's caregiver. Methods of administering such nutritional compositions to patients in need of same are also provided | 08-15-2013 |
20130209374 | PROBIOTIC COMPOSITION FOR ORAL HEALTH - The present invention provides a composition comprising an effective amount of | 08-15-2013 |
20130236398 | ANTIBODIES THAT BIND TO NANOPARTICLES - Antibodies and antibody fragments that selectively bind to nanoparticles are provided herein. | 09-12-2013 |
20130280179 | Chewing Gum Composition Comprising Cross-Linked Polyacrylic Acid - The present invention provides a chewing gum composition comprising a gum base matrix and a bulk portion, wherein the chewing gum composition comprises nicotine and includes a cross-linked polyacrylic acid, such as a carbomer, added in an amount of 0.1 to 5.0% by weight of the chewing gum composition. The invention may be used to enhance the release of nicotine in a nicotine chewing gum. | 10-24-2013 |
20130295025 | USE OF BETA-ADRENERGIC INVERSE AGONISTS FOR SMOKING CESSATION - The chronic use of p-adrenergic inverse agonists such as nadolol, carvedilol, and ICI-118,551 provides an improved method for the treatment of mucus hypersecretion in subjects with such mucus hypersecretion. One aspect of a method according to the present invention is a method of preventing or controlling mucus hypersecretion in the respiratory tract comprising administering a therapeutically effective quantity of a p-adrenergic inverse agonist to a subject with mucus hypersecretion or at risk of mucus hypersecretion. The invention further encompasses pharmaceutical compositions comprising the p-adrenergic inverse agonist and the additional compound. | 11-07-2013 |
20130295026 | FAST DISINTEGRATING COMPOSITIONS COMPRISING NABILONE AND RANDOMLY METHYLATED BETA CYCLODEXTRIN - The present invention provides a novel composition comprising Nabilone and randomly methylated B-cyclodextrin (RAMEB), wherein the weight ratio (dry weight to dry weight) between Nabilone and RAMEB is about 1:60-1:140. The present invention further provides methods for increasing the bioavailability of Nabilone. | 11-07-2013 |
20130302261 | EXOPOLYSACCHARIDE FOR TREATMENT OR CARE OF SKIN, MUCOUS MEMBRANES, HAIR OR NAILS - A method includes administering a cosmetically or dermopharmaceutically effective quantity of exopolysaccharide of a bacterial strain isolated from | 11-14-2013 |
20130315843 | COMPOSITION FOR REDUCTION OF TRPA1 AND TRPV1 SENSATIONS - A personal care composition and method of using a personal care composition having menthol and/or hydrogen peroxide and a TRPA1 and/or TRPV1 receptor antagonists. | 11-28-2013 |
20130323184 | Method Of Providing Fast Relief To A User Of A Nicotine Chewing Gum - The invention relates to a method of relieving nicotine craving comprising the steps of providing at least one chewing gum comprising tobacco alkaloid to a user, providing relief of nicotine craving to said user by transferring of tobacco alkaloid from the chewing gum to the human body of said user by chewing of said chewing gum, said chewing of said chewing gum comprising a chewing process involving a transfer of tobacco alkaloid from said chewing gum above a threshold transfer rate in the period of about ½ minute to about 2½ minutes from initiation of said chewing process. | 12-05-2013 |
20130344007 | FRANKINCENSE CHEWING GUM - This disclosure relates to a composition that may include frankincense resin and various combinations of essential oils, which combinations may be effective in promoting weight loss. The present disclosure further relates to a weight loss and satiation composition that may include frankincense resin and a flavorant. In some embodiments, the composition may include a gum base. | 12-26-2013 |
20140017177 | SILENE CAPENSIS FOR INHIBITING CRAVINGS - A composition can include: silene extract; and a carrier having the silene extract. The composition can include an active agent, such as a pharmaceutical or a nutraceutical. The composition can be in a form of a solid, paste, gel, gum, or combination thereof. The carrier can facilitate retention in the mouth, chewing, sucking, holding in the lip next to the gums, or other non-liquid format. A method can provide an alternative to an activity that reduces desire to perform the activity, the method can include: administering to a subject in need thereof the composition having silene. The method can include administering the composition in an effective amount to treat one or more of smoking dependence, tobacco withdrawal symptoms, and tobacco dependence in the subject, wherein the activity is smoking. | 01-16-2014 |
20140030194 | Compositions and Methods for the Treatment of Hepatic Diseases and Disorders - The disclosure provides oral compositions and methods of using such compositions in treating subjects infected with one or more hepatic disorders. The compositions include lysates or cell wall extracts of one or more gram positive bacteria, exhibit particular activity against hepatitis C virus (HCV), and may be useful in treating those infected with HCV as well as other hepatic diseases or disorders. Also described are methods of treating a hepatic disease or disorder by administering a therapeutically effective amount of at least one therapeutically active agent capable of upregulating or downregulating the Complement system pathway, wherein the therapeutically active agent enhances the formation of one or more convertase enzymes. | 01-30-2014 |
20140056824 | IONIC COMPLEXES - The present invention provides a phosphopeptide or phosphoprotein (PP) stabilised amorphous calcium phosphate or amorphous calcium fluoride phosphate complex having a calcium ion greater than about 30 moles of calcium per mole of PP. | 02-27-2014 |
20140086849 | Naturally-Occurring CpG Oligonucleotide Compositions and Therapeutic Applications Thereof - The present invention relates to combination therapies for the treatment of a variety of disorders in mammals, including hepatic disorders and cancer. The combination of agents includes naturally-occurring (versus synthetic) oligonucleotides, particularly immunostimulatory oligodeoxynucleotides such as CpG ODNs, obtained from a natural source and one or more extracts from a Gram positive bacteria, such as | 03-27-2014 |
20140099269 | CHEWING GUM HAVING SUSTAINED RELEASE OF NICOTINE - The present invention relates to a chewing gum having a high Surface Area to Volume ratio (SAV ratio), wherein said chewing gum comprises a water insoluble gum base matrix, a water soluble bulk portion and nicotine, wherein the gum base matrix, nicotine and the bulk portion are mixed and extruded to form a final extruded chewing gum product having a SAV ratio above 0.7, and wherein sustained release of nicotine is facilitated by adding 0.1-10% of C8-C10 triglycerides by weight of the chewing gum. | 04-10-2014 |
20140120040 | ORAL HYGIENE KITS AND METHODS OF PROVIDING SAME - Oral hygiene kits and methods of providing same are provided. The oral hygiene kit can include a tooth cleaning device, a food product and a xylitol-containing item selected from the group consisting of a candy, a chewing gum and a combination thereof. A method of reducing tooth decay in a student can include the steps of providing to the student an oral hygiene kit comprising a tooth cleaning device, a food product and a xylitol-containing item selected from the group consisting of a candy, a chewing gum and a combination thereof while the student is at school. In an embodiment, the food product does not have a low pH and/or does not have high fructose corn syrup. | 05-01-2014 |
20140134113 | PHARMACEUTICAL COMPOSITIONS - Suggested is a pharmaceutical composition, comprising menthane carboxylic acid-N-(4-methoxy-phenyl)-amide. | 05-15-2014 |
20140161739 | HYDROPHILIC GUM BASE - A gum base comprising: a) a hydrophilic precursor component comprising hydrolysable units; and b) a copolymer of a hydrophilic monomer with a second monomer selected from vinyl acetate, isobutylene, isoprene, butyl rubber or styrene butadiene. This chewing gum base contributes to the ability of the chewing gum compositions and chewing gum products to degrade over time after chewing by imparting the chewing gum with increased hydrophilic properties. | 06-12-2014 |
20140193345 | HERBAL COMPOSITIONS FOR THE TREATMENT OF MUCOSAL LESIONS - The present invention provides therapeutic compositions comprising extracts of the plant species | 07-10-2014 |
20140294739 | COMPOSITIONS CONTAINING ZINC SALTS AND ISOTHIOCYANATES FOR REDUCTION OF ORAL VOLATILE SULFUR COMPOUNDS (VSCs) - Combinations of a zinc salt and an isothiocyanate are provided, and more particularly to a consumer acceptable oral composition containing such combination which is effective in the reduction of volatile sulfur compounds (VSCs). | 10-02-2014 |
20140314685 | ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF - Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia. | 10-23-2014 |
20140314686 | POLYPHENOL/FLAVONOID COMPOSITIONS AND METHODS OF FORMULATING ORAL HYGIENIC PRODUCTS - Microemulsions and soluble alkali metal salts of relatively insoluble aglycone polyphenols within oral hygienic products are disclosed for treating oral inflammatory disorders. The formulations can act as a bactericide or bacteriostat. The methods include the process associated with the formation of a high temperature polyphenol/surfactant concentrate, a nano-particulate precipitation process in the presence of a surfactant and the solubilization of relatively insoluble aglycone polyphenols/flavonoids by the formation of soluble alkali metal salts within alkaline oral compositions. | 10-23-2014 |
20140356297 | ORAL COMPOSITIONS FOR ABSORPTION OF PHOSPHOROUS COMPOUNDS - The present invention provides medicaments useful for reducing phosphorus serum level, especially in those subjects affected from hyperphosphatemia. More specifically, the present invention relates to pharmaceutical compositions to be administered by oral route in fasting periods, in order to absorb phosphorus compounds from fluids of the enteric tract, especially from saliva. | 12-04-2014 |
20150125402 | ANTIMICROBIAL AGENTS - Compounds are used in compositions as antimicrobial agents against microbes, such as for example, | 05-07-2015 |
20150290106 | Dentotropic Conjugates and Compositions and Methods of Use Thereof - Compositions and methods for targeting agents, particularly a flavoring, fragrant, or cooling agent such as menthol, to tooth are provided. | 10-15-2015 |
20150293075 | METHOD FOR TESTING ORAL MALODOR - The present invention relates to a method for testing oral malodor, in particular oral malodor from coffee. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a sample of exhaled breath from the cleaned oral cavity to provide a test result representing a amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a sample of exhaled breath from the oral cavity to provide a test result representing an amount of the at least one oral malodor component detected in the exhaled breath. | 10-15-2015 |
20150297468 | ORAL DELIVERY SYSTEM - The present invention provides a delivery system for the treatment and/or prevention of infectious pathological changes, including compositions comprising polyhexanide, various pharmaceutical formulations, and processes for using these formulations in oral treatment modalities. | 10-22-2015 |
20150313820 | PREPARATIONS - Proposed are preparations, comprising special amides and menthol or menthol compounds or aromatic substances, characterized in that they have improved flavor and scent properties, and also that they allow the production of preparations, particularly emulsions with improved shelf life. | 11-05-2015 |
20160000679 | LACTONE-CONTAINING COMPOSITIONS FOR MALODOR ELIMINATION - The presently disclosed subject matter provides lactone-containing malodor eliminating compositions that ameliorate undesirable malodor, e.g., undesirable malodor due to presence of sulfur- or amine-containing compounds. The presently disclosed compositions can be added to a variety of products, including, but not limited to, foods, beverages, toothpastes, mouthwashes and other orally consumable products. | 01-07-2016 |
20160000695 | METHODS AND COMPOSITIONS FOR TREATMENT OF HALITOSIS - Methods and compositions for treatment of halitosis are provided. Devices and methods, such as a palatal patch, including a tablet or strip having a bioadhesive component and active ingredients are further provided. The bioadhesive component allows for the palatal patch to be attached to an upper palate, and for the active component to be released into the oral cavity and/or GI tract. Compositions for the active ingredient include composition for treatment of halitosis, anti-acids, vitamins, anti-smoking agents, etc. A herbal composition for treatment of halitosis including | 01-07-2016 |
20160000845 | EXTRACT OF TRIGONELLA FOENUM-GRAECUM - Disclosed herein is an extract obtainable from | 01-07-2016 |
20160008297 | COMPOUNDS FOR PREVENTING, REDUCING AND/OR ALLEVIATING ITCHY SKIN CONDITION(S) | 01-14-2016 |
20160008322 | ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF | 01-14-2016 |
20160051495 | Oral Transmucosal Compositions including C-SERMs for Low Testosterone Levels in Men - Formulations for oral transmucosal compositions that include clomiphene-like selective estrogen receptor modulators (C-SERMs) in combination with transmucosal absorption enhancers are disclosed. Oral transmucosal compositions can be for fast release or slow release, and can be administered to increase bloodstream testosterone levels and thereby reduce symptoms of testosterone deficiency. Oral transmucosal compositions include liquid dosage forms, solid dosage forms, and chewing gums. Further dosage forms include mucoadhesive thin strips, thin films, tablets, patches, and tapes, among others. Other dosage forms are: mucoadhesive liquids such as gel-forming liquid; gel-forming; semisolids; and gel-forming powders, among other dosage forms that exhibit mucoadhesive properties, and provide oral transmucosal delivery of C-SERMs. Oral transmucosal compositions allow the delivery of C-SERMs directly into the patient's bloodstream, thereby providing high bioavailability of C-SERMs; therefore, required dose is lower. | 02-25-2016 |
20160051496 | Oral Transmucosal Compositions Including C-SERMs for Treating Female Infertility - Formulations for oral transmucosal compositions including clomiphene-like selective estrogen receptor modulators (C-SERMs) in combination with transmucosal absorption enhancers are disclosed. Oral transmucosal compositions can be for fast release or slow release, and can be administered to induce ovulation in a female patient and thereby reduce symptoms of anovulatory infertility, unexplained infertility, and the like. Oral transmucosal compositions include liquid dosage forms, solid dosage forms, and chewing gums. Further dosage forms include mucoadhesive thin strips, thin films, tablets, patches, and tapes, among others. Other dosage forms are: mucoadhesive liquids, such as, for example gel-forming liquid; gel-forming semisolids; and gel-forming powders, among other dosage forms that exhibit mucoadhesive properties, and provide oral transmucosal delivery of C-SERMs. Oral transmucosal compositions will deliver C-SERMs directly into the patient's bloodstream, and provide high bioavailability of C-SERMs; therefore, the required doses are lower. | 02-25-2016 |
20160089361 | CONTROLLED RELEASE ORAL FORMULATIONS OF ION CHANNEL MODULATING COMPOUNDS AND RELATED METHODS FOR PREVENTING ARRHYTHMIA - The present invention provides methods of treating and preventing arrhythmia and other diseases or disorders, using ion channel modulating compounds, including vernakalant hydrochloride. The present invention further provides controlled release oral formulations and dosages of vernakalant hydrochloride, which are effective in preventing arrhythmia. Certain methods and formulations of the present invention are adapted for the treatment and prevention of arrhythmia and other disease or disorders in subjects identified as having altered drug metabolism due to polymorphism of the gene encoding cytochrome P450 2D6. | 03-31-2016 |
20160100574 | Antimicrobial Compositions Comprising Glyceryl Ethers - Suggested is an antimicrobial agent comprising at least one glycerylether of formula (I) in which R | 04-14-2016 |
20160113985 | COMPOSITION AND METHOD FOR REDUCING FOOD INTAKE - The present invention features a composition and method for reducing food intake. The composition of the invention is composed of yerbe maté extract, guarana extract, and damiana extract in combination with a dietary fiber. | 04-28-2016 |
20160143928 | BOVINE MILK OLIGOSACCHARIDES - Oligosaccharides from bovine milk, whey and dairy products, and methods of producing bovine milk oligosaccharides are provided. | 05-26-2016 |
20160158283 | COMPOSITIONS AND METHODS FOR DENTAL MINERALIZATION - The present invention relates to compositions for mineralizing a dental surface, in particular tooth enamel. Methods of mineralizing hypomineralized lesions (including subsurface lesions) in the tooth enamel caused by dental caries, dental corrosion and fluorosis are also provided. In particular, the invention relates to a method of mineralizing a dental surface or subsurface comprising contacting the dental surface or subsurface with a compound that is capable of increasing or maintaining the pH of a solution and a mineralizing agent. | 06-09-2016 |
20160201110 | DIAGNOSIS AND TREATMENT OF INCIPIENT DIABETES | 07-14-2016 |
20160250127 | USE OF A POLYOL IN THE REMINERALISATION OF ENAMEL | 09-01-2016 |
20180021389 | SYNERGISTIC COMPOSITION COMPRISING PROPOLIS AND CARNOSIC ACID FOR USE IN THE PREVENTION AND TREATMENT OF CANDIDIASIS | 01-25-2018 |
20190142724 | PERSONAL DENTAL CARE PRODUCT FOR CARIES TREATMENT | 05-16-2019 |