| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 422070000 | Liquid chromatography | 24 |
| 20080240993 | IMMUNOCHROMATOGRAPHY TEST TOOL - An objective of the present invention is to provide an immunochromatography test tool having high detection sensitivity without leakage of a test solution to a space formed between an edge of a test piece and edge of a lower cover, in an immunochromatography test tool utilizing an antigen-antibody reaction. The immunochromatography test tool includes an upper cover having a test solution dropping window and a test result detection window, a lower cover having a test piece setting guide, and a test piece housed between the upper cover and the lower cover. In the test tool, contact angles of inner surfaces of the upper and lower covers are 60° to 150° with respect to water. The inner surfaces of the upper and lower covers are preferably subjected to a water repellent treatment. | 10-02-2008 |
| 20080286153 | Affinity Chromatography Microdevice and Method for Manufacturing the Same - An affinity chromatography microdevice includes a top board and a bottom board. The top board includes an inlet and an outlet through which microfluid flows, and a reaction chamber for limiting the flow of the microfluid for reaction. The bottom board includes a microelectrode for independently controlling a micro-temperature, and a thermosensitive polymer matrix formed on the microelectrode. The thermosensitive polymer matrix is contracted or expanded according to temperature change. | 11-20-2008 |
| 20080311003 | Stoppable test device - A lateral flow chromatography test device is disclosed that includes a stopping mechanism which enables a user of the test device to stop reactions of a test by pushing the stopping mechanism downward to remove materials flowing along a test strip in the test device at a time instructed by the manufacturer or decided by the user. This stopping mechanism is adapted to freeze the test result at the stopping time so as to keep the test result as a permanent record. The invention enables qualitative tests to become quantitative or semi-quantitative tests. | 12-18-2008 |
| 20090175766 | VISUALIZATION OF CHEMICAL-ANALYSIS DATA - A method includes compressing chemical-analysis data points with no loss of information, generating, from the stored data points, nested data arrays, storing the nested data arrays in a video memory, rendering an image from the nested data arrays, and displaying the rendered image. A chemical-analysis instrument includes a chromatography module, a mass-spectrometry module that receives an eluent from the chromatography module, a computer unit that receives data points from the chromatography and mass-spectrometry modules, and a monitor for displaying rendered images. | 07-09-2009 |
| 20090214386 | Coupling of conduits with melted and solidified plastic material - A method of coupling at least two conduits for bringing them in communication. Each of the conduits is adapted for conducting a medium and has an outlet and an outer surface adjacent to the outlet. The outer surfaces and a solid plastic material are at least partly inserted into an aperture of a coupling element. The plastic material is plastified and/or melted at least partly. The plastic material is solidified for sealing and fixing the conduits within the aperture of the coupling element. | 08-27-2009 |
| 20090232706 | Novel method for chromatographic finger printing and standardization of single medicines and formulations - The present invention provides a method for the chromatographic fingerprinting, chemical and therapeutic standardization, bar-coding of the fingerprints and preparation of a data base for Enterprise Resource Planning (ERP) and Customer Relationship Management (CRM) machines and applications of medicines in general and traditional medicines in particular; this invention includes a software based instrumental method and a novel method of fingerprinting and standardization is proposed for the above purpose and the said method for the chromatographic finger printing which facilitates to correlate the traditional therapeutic standardization methods with the chemical properties of the medicines and humors and provides a rational basis to understand the methods used for the said purpose. | 09-17-2009 |
| 20100086443 | Flow Rate Control - A liquid sample is prepared at a preparation site and then processed, e.g. in an HPLC column. The sample is prepared and conveyed to the device at a flow rate which is substantially less than the flow rate through the device. The different flow rates are preferably provided by variable rate working fluid supplies which drive the sample from the preparation site and through the device. | 04-08-2010 |
| 20100098587 | CHROMATOGRAPHY QUANTITATIVE MEASURING APPARATUS - In a chromatography quantitative measuring apparatus according to the present invention, a beam applied from a light source to a chromatography test strip is formed into an elliptical shape by an optical means such as a cylindrical lens, a variation in absorbance that accompanies elution of a marker regent is detected while the elliptical beam is applied between a marker reagent hold part and a detection part, and a measurement is automatically started in a prescribed period of time since the detection of variation. According to the chromatography quantitative measuring apparatus so configured, non-uniform coloration is reduced by shaping the beam elliptically with the optical means, whereby the accuracy of quantitative analysis is enhanced, and the apparatus can be operated easily. | 04-22-2010 |
| 20100104475 | CHROMATOGRAPHY QUANTITATIVE MEASURING APPARATUS - In a chromatography quantitative measuring apparatus according to the present invention, a beam applied from a light source to a chromatography test strip is formed into an elliptical shape by an optical means such as a cylindrical lens, a variation in absorbance that accompanies elution of a marker regent is detected while the elliptical beam is applied between a marker reagent hold part and a detection part, and a measurement is automatically started in a prescribed period of time since the detection of variation. According to the chromatography quantitative measuring apparatus so configured, non-uniform coloration is reduced by shaping the beam elliptically with the optical means, whereby the accuracy of quantitative analysis is enhanced, and the apparatus can be operated easily. | 04-29-2010 |
| 20100166611 | DEVICE FOR THE DISTRIBUTION OF SAMPLE AND CARRIER LIQUID ACROSS A MICRO-FABRICATED SEPARATION CHANNEL - The present invention relates to a chromatographic separation device comprising a first substrate body carrying a micro-fabricated separation channel recessed on one of its surfaces and covered by a second substrate body, both perforated with connection-holes for the supply and withdrawal of a sample and carrier liquid. The present device is characterized in that said micro-fabricated separation channel is preceded or succeeded by a flow distribution region that is filled with an array of micro-fabricated pillars, having a shape, size and positioning pattern selected such that said flow distribution region has a ratio of transversal to axial permeability of at least 2. | 07-01-2010 |
| 20100189602 | SEPARATION DEVICE WITH MOVEABLE FILLING CHANNEL - A separation device includes a separation chamber having a housing for housing a stationary phase configured for separating compounds of a fluid sample. The separation device also includes a filling port configured for filling the stationary phase through a filling channel into the separation chamber, and a locking piece comprising the filling channel. The locking piece is configured to move the filling channel from a first position, wherein an opening of the filling channel is opening into the separation chamber for filling the stationary phase into the separation chamber, to a second position, wherein the separation chamber is locked against the filling channel. The locking piece is configured to move the opening of the filling channel substantially laterally with respect to the housing. | 07-29-2010 |
| 20100278695 | Chromatographic And Electrophoretic Separation Media And Apparatus - The invention provides improved separation media for use in chromatography and electrophoresis, or for the selective absorption of certain components of a sample mixture, especially in a preliminary stage of an analysis. Improved media according to the invention comprises first particles capable or retaining one or more of the components of a sample mixture and second particles selected to have a higher thermal conductivity than the first particles, so that the thermal conductivity of the media is higher than that of media comprising the first particles alone. The media may be incorporated in packed or capillary columns for chromatography (especially nanoflow HPLC) or for capillary electrophoresis, or may be coated on a substrate. Particular embodiments of the media may comprise mixtures of first particles comprising siliceous polymers, second particles of gold, diamond or graphite. Chromatographic columns and apparatus incorporating them are also disclosed. | 11-04-2010 |
| 20100284861 | SUPPRESSOR AND ION CHROMATOGRAPH EMPLOYING THE SAME - A suppressor which comprises: an ion-exchange membrane; an eluate channel which is in contact with one side of the ion-exchange membrane, serves as a channel through which an eluate discharged from a separation column flows, and has inside no obstacle to the flow; a regenerant channel which is in contact with the other side of the ion-exchange membrane, serves as a channel through which a regenerant for regenerating ionic functional groups of the ion-exchange membrane flows, has been disposed so that the regenerant channel has no region facing the eluate channel and extends in parallel to the eluate channel in such a nearby position that the ionic functional groups can move through the ion-exchange membrane, and has inside no obstacle to the flow; and an ion-exchange membrane support member which is in contact at least with that region on one side of the ion-exchange membrane which is opposed to the regenerant channel and with that region on the other side of the ion-exchange membrane which is opposed to the eluate channel to thereby support the ion-exchange membrane with wall surfaces. | 11-11-2010 |
| 20110064616 | TRANSPORT DETECTOR FOR LIQUID CHROMATOGRAPHY - A transport detector for Liquid Chromatography includes a spinning disk covered in a non-wettable, non-transparent material with a wettable transparent channel left for a mobile phase. A mobile phase is delivered from a chromatography column into the channel. A light source with focusing optics is set along the channel path and array of sensors for optical signal detection are mounted along the path of the light. The disk rotation could be set at different speeds by a motor, allowing the operator to control the thickness of the liquid layer in the channel. Varying the thickness of liquid changes the length of the optical cell of the detector, which allows adjusting the sensitivity of the detector. The spinning disk design allows for using of multiple sensors of different kind as well as different detection methods. Also, the array of sensors of the same kind could be used to perform multiple measures of the same portion of the mobile phase. This feature improves the Signal to Noise ratio of the detector. The detector has a wiping and vacuuming device at the end of the channel's circular path to regenerate the channel for the new mobile phase entry. | 03-17-2011 |
| 20110211992 | FLUID CHROMATOGRAPHY INJECTORS AND INJECTOR INSERTS - Certain embodiments described herein are directed to injector inserts and injector assemblies. In some examples, an injector insert that includes an inlet comprising a substantially inert metal is described. In other examples, an injector that includes a major amount of a substantially inert metal in a fluid flow path is disclosed. Devices and systems using the injectors inserts and injectors are also described. | 09-01-2011 |
| 20110211993 | JET ASSEMBLY FOR USE IN DETECTORS AND OTHER DEVICES - Certain embodiments described herein are directed to jet assemblies that include a substantially inert fluid flow path. In some examples, a jet assembly includes a fluid flow path comprising a substantially inert metal in a fluid flow path. Devices and systems using the jet assembly are also described. In other embodiments, a brazeless or weldless jet assembly is provided. In some embodiments, the brazeless jet assembly may include an inert material or coating, e.g., a silica coating, in a fluid flow path. | 09-01-2011 |
| 20120141328 | CHEMICAL SUPPRESSORS AND METHOD OF USE - A non-electrolytic method and apparatus for treating an aqueous sample stream including analyte ions and matrix ions of opposite charge, for pretreatment or suppression. The apparatus includes an ion exchange membrane capable of passing only ions of opposite charge to the analyte ions, a sample stream flow channel, a first aqueous stream ion receiving flow channel adjacent one side of the sample stream flow channel and separated therefrom by the first ion exchange membrane, and stationary flow-through ion exchange packing disposed in the sample stream flow channel. The ion receiving channel has an ion exchange capacity for the matrix ions less than about 25% of the ion exchange capacity for the matrix ions. | 06-07-2012 |
| 20120275958 | DETERMINATION METHOD AND INSTRUMENTS OF HEXAVALENT CHROMIUM - A transparent or translucent column is used for an analytical method for quantifying hexavalent chrome in a liquid sample. The method includes adding a reagent for complex formation to a liquid sample to form a colored chelate of hexavalent chrome, adding a salting-out agent to the liquid sample, then contacting the liquid sample which an adsorbent, and measuring a thickness of a colored layer of the adsorbent. The column is filled with a mixture of the adsorbent and glass wool, and provided with a scale on the side, thereby allowing a thickness of a colored layer of the adsorbent to be read from outside. | 11-01-2012 |
| 20130052083 | COLUMN HEATER WITH ACTIVE PRE-HEATING - To heat a flowing liquid, an apparatus includes a heater block assembly having a heater block made of thermally conductive material. The heater block assembly has a tube inlet, a tube outlet, and a tube path between the tube inlet and tube outlet. Tubing extends through the tube path from the tube inlet to the tube outlet. The tubing is in thermal communication with the heater block. A heater cartridge, in thermal communication with the heater block, is configured to provide heat to the heater block for transfer to liquid flowing through the tubing between the tube inlet and the tube outlet of the heater block assembly. Circuitry is in electrical communication with the heater cartridge to control a temperature of the heater block by controlling operation of the heater cartridge. | 02-28-2013 |
| 20130089468 | SEPARATION/DETECTION COLUMN AND KIT THEREOF - Disclosed is a separation/detection column that can detect a component separated by a separating agent having optical responsivity which is the same as that of a component in a sample. The separation/detection column is configured by filling one end of a tube | 04-11-2013 |
| 20130243654 | HIGH-SPEED, AUTOMATED CHROMATOGRAPHIC ANALYZER FOR DETERMINATION OF NONGLYCATED AND GLYCATED PROTEINACEOUS SPECIES IN BLOOD SAMPLES - High-speed, automated analyzers for analyses of biological fluids, such as whole blood or blood-derived components, include specialized analyzer and sample transfer features permitting injection-to-injection analysis times on the order of one minute. The analyzers are particularly designed for HPLC analysis for glycated and nonglycated proteinaceous species in blood samples. | 09-19-2013 |
| 20140004001 | LARGE CAPACITY ACID OR BASE GENERATOR AND METHOD OF USE | 01-02-2014 |
| 20140134050 | SUPPRESSOR DEVICE - An apparatus for detecting analytes in a liquid sample may include an elongated primary channel through which an ionic species flows, the primary channel extending through a primary channel member, a first regenerant channel through which a regenerant flows, the first regenerant channel extending adjacent to the primary channel and being formed in a first block, a first charged barrier having exchangeable ions capable of passing ions of only one charge, positive or negative, and of blocking bulk liquid flow, the first charged barrier disposed between the primary channel member and the first block for separating the primary channel from the first regenerant channel, and a first sealing member disposed between the first charged barrier and the first block defining the first regenerant channel. | 05-15-2014 |
| 20160109417 | Adsorbent and Analysis Method Using Same - An adsorbent which enables solid phase extraction of water-soluble molecules with high efficiency and excellent selectivity and an analysis system using the adsorbent, the adsorbent containing a structure represented by the formula I | 04-21-2016 |
