Class / Patent application number | Description | Number of patent applications / Date published |
422052000 | Chemiluminescent | 41 |
20080240983 | Modular assay reader system and apparatus - A modular reader system and method provides for testing a test sample and determining characteristics of the sample. A first test module is configured to perform a first reading on a test sample and produce data regarding the reading. A second test module is configured to perform a second reading of the test sample and produce data regarding the second reading. The first and second test modules are communicatively coupled to a control module. The control module collects the data produced by the first and second test modules and processes the data to determine characteristics of the test sample. | 10-02-2008 |
20080247906 | Luminescence Sensor for Determining and/or Monitoring an Analyte that is Contained in a Fluidic Process Medium - A device for determining and/or monitoring an analyte contained in a fluidic process medium. The device comprises a sensor, which contains a process membrane with a porous support structure, a luminescent substance, that comes into contact with the analyte or gaseous process medium, being embedded in said support structure, an emitter unit, whose radiation excites the luminescent substance, causing it to emit luminescent radiation, a receiver unit, which detects the luminescent radiation and a control/evaluation unit, which determines the concentration or the partial pressure or pressure of the analyte using the quenching of the luminescent radiation of the luminescent substance. According to the invention, the porous support structure comprises plastic, ceramic, metal or foamed plastic. | 10-09-2008 |
20080260577 | CHEMILUMINESCENT DETECTION SYSTEM - Throughput is improved by increasing the number of micro-reaction chambers. There is provided a chemiluminescent detection system that has a so-called plate on which many reaction chambers are one-dimensionally or two-dimensionally arranged, characterized in that optical detection is performed using a line or area sensor having many detection pixels, the spacing of the optical detection pixels substantially matches the spacing of the reaction chambers on the plate, and the micro-reaction chambers and the pixels are made to correspond one-to-one with each other so that light from the reaction chambers on the plate enters the detection pixels most efficiently and does not scatter to other pixels. To make the micro-reaction chambers arrayed on the plate and the pixels of the image pickup element plate correspond one-to-one with each other, light-emitting substances or reflectors or photoabsorption substances are placed so as to serve as alignment marks. | 10-23-2008 |
20080317627 | CHEMILUMINESCENCE ANALYZER - The present invention aims to achieve both rapid supply of reagent substances to micro-chambers and inhibition of contamination from adjacent chambers. For achieving the above objects, the shape of a flow channel in a flow cell including a plate having micro-chambers is varied between the time of substance supply and the time of luminescence reaction. | 12-25-2008 |
20090191092 | OPTICAL PROBE - An optical probe for detecting luminescence emitted by a sample is disclosed. The optical probe includes a parabolic optical waveguide and an outer housing having a detachable component configured to hold a transparent sensor substrate that can be coupled to the optical waveguide. The optical probe also includes a sensing material for detection of at least one specified analyte. An excitation source is configured to excite the sensing material. The optical probe also incorporates a measuring photodetector that detects emitted luminescence. | 07-30-2009 |
20090208370 | DRUG DISCOVERY SCREENING DEVICE - An object of the invention is to implement a drug discovery screening device having high throughput and high accuracy. The drug discovery screening device is provided with a Nipkow disc type confocal scanner for irradiating excitation light on samples placed on a well plate, and executing image processing based on fluorescent signals from the samples, and comprises a confocal scanner for irradiating a plurality of excitation lights and to which a plurality of fluorescent signals are incident, and a plurality of objectives lenses for irradiating a plurality of excitation lights emitted from the confocal scanner on the plurality of samples, to which the plurality of fluorescent signals generated from the plurality of samples are incident, and bringing the plurality of fluorescent signals to the confocal scanner. | 08-20-2009 |
20090246076 | ELECTROCHEMILUMINESCENCE FLOW CELL AND FLOW CELL COMPONENTS - An electrochemiluminescence cell comprising an electrode capable of inducing an electrochemiluminescence-active species to electrochemiluminesce. The electrode is preferably made of rhodium, iridium or an alloy of platinum, rhodium or iridium alloyed with an alloy material comprising a transition element. The electrode may be used as counter electrode and/or as a working electrode in the electrochemiluminescence cell. The cell preferably includes a counter electrode and a support attached to the counter electrode. The support comprises a transparent portion in optical registration with the working electrode. The counter electrode may include one or more field extending elements interposed between the transparent portion and the working electrode. The field extending element is preferably a ladder or a grid. | 10-01-2009 |
20090252649 | Apparatus for body fluid analysis using surface-textured optical materials - A variety of characteristics of body fluid may be measured by introducing a sample to a textured surface on optical material such as waveguides and sheets. The textured surface presents a field of elongated projections which are spaced apart to exclude certain components of the body fluid sample from entering into the spaces between the projections, while permitting other parts of the body fluid sample which contains the analyte to enter into those spaces. The analyte contacts a chemistry on the surface which is sensitive to the analyte, whereupon the analyte and the analyte-sensitive chemistry interact in a manner that is optically detectable. The optical material is packaged in suitable structures such as elongated cylinders, flat test strips, and sheets. A structure containing the optical material is mounted on a detector, which both illuminates the optical material and detects and analyzes the light that returns from the textured surface. | 10-08-2009 |
20090324446 | APPARATUS FOR SENSING NITROAROMATICS - The subject invention pertains to a method and apparatus for sensing nitroaromatics. The subject invention can utilize luminescent, for example fluorescent and/or electroluminescent, aryl substituted polyacetylenes and/or other substituted polyacetylenes which are luminescent for sensing nitroaromatics. In a specific embodiment, the subject invention can utilize thin films of fluorescent and/or electroluminescent aryl substituted polyacetylenes and/or other substituted polyacetylenes which are fluorescent and/or electroluminescent. In a specific embodiment, the fluorescence from thin films of fluorescent, substituted polyacetylene, such as—poly-[1-phenyl-2-(4-trimethylsilylphenyl)ethyne] (PTMSDPA) is strongly quenched by the vapors of a variety of nitroaromatic compounds present at levels ranging from parts-per-million to parts-per-billion in air. | 12-31-2009 |
20100054991 | LUMINOMETER AND METHODS OF OPERATION - The present invention is directed to a luminometer and methods which provides simple and effective measurement of a plurality of wells in a plurality of strips in an automatic fashion. The luminometer may be used in CLIA (Chemi Luminescent Immuno Assays). The luminometer allows for CLIA micro strip reading, and reads break-apart wells, with a plurality of wells per strip, and calculates results instantly and automatically. The luminometer has an automatic carrier positioning system which selectively positions the plurality of wells in the plurality of strips at a measuring position, wherein the drive system associated with the positioning system drives the carrier along a single axis of movement. An optical track system automatically provides Y axis movement of the carrier. The luminometer may have a calibration system for maintaining proper operation of the system in measurements therewith. | 03-04-2010 |
20100074799 | Fluidic Medical Devices and Uses Thereof - This invention is in the field of medical devices. Specifically, the present invention provides fluidic systems having a plurality of reaction sites surrounded by optical barriers to reduce the amount of optical cross-talk between signals detected from various reaction sites. The invention also provides a method of manufacturing fluidic systems and methods of using the systems. | 03-25-2010 |
20100086439 | CHEMICAL SUBSTANCE SENSING ELEMENT, CHEMICAL SUBSTANCE SENSING APPARATUS, AND METHOD OF MANUFACTURING CHEMICAL SUBSTANCE SENSING ELEMENT - A chemical substance sensing element | 04-08-2010 |
20100111762 | INTEGRATED BIO-CHIP, METHOD OF FABRICATING THE INTEGRATED BIO-CHIP, AND APPARATUS FOR DETECTING BIO-MATERIAL - An integrated bio-chip includes a substrate and one or more excitation light absorbing waveguides disposed in the substrate. The substrate includes one or more reaction regions on which samples are disposed. An end portion of each of the one or more excitation light absorbing waveguides is exposed from the substrate at an upper surface thereof, another end portion of each of the one or more excitation light absorbing waveguides is exposed from the substrate at a lower surface thereof, and the one or more reaction regions are disposed at a upper surface of the substrate. The one or more excitation light absorbing waveguides absorbs excitation light incident to the samples, and transmits fluorescent light emitted from the samples. | 05-06-2010 |
20100202922 | DEVICE FOR OPTOELECTRONICALLY CHARACTERIZING SAMPLES | 08-12-2010 |
20100202923 | Grating-based sensor combining label-free binding detection and fluorescence amplification and readout system for sensor - A grating-based sensor is disclosed that has a grating structure constructed and designed for both evanescent resonance (ER) fluorescence detection and label-free detection applications. One and two-dimensional gratings are also disclosed, including gratings characterized by unit cells with central posts, central holes, and two-level, two-dimensional gratings. A readout system for such sensors is also disclosed. Various applications for the biosensors are described, including cell-based assays for assessing the effect of drug compounds on cell function. A biosensor embodiment optimized for a luminescent response at two different wavelengths is also described. Such luminescent response could be produced by fluorescence (either native or from an attached fluorophore), phosphorescence, chemi-luminescence, or other luminescence technology. Two different luminescence technologies could be combined on the same biosensor chip. | 08-12-2010 |
20110008210 | BIOSENSOR AND A RELATED MANUFACTURING METHOD - A biosensor platform for a biosensor adapted to detect one or more predetermined target analytes in a sample, includes a waveguide for transporting light emitted by a light source, at least one light source including an OLED, for incoupling light to the waveguide, the light source being arranged on the waveguide, a binding site including immobilized biorecognition material capable of binding to the target analytes, the binding site positioned relative to the waveguide such that evanescent field triggered by the light propagating in the waveguide extend to the binding site, a microfluidic layer including one or more microfluidic cavities for conveying the sample past the binding site to enable at least part of the target analytes of the sample to bind to the immobilized biorecognition material. The biosensor platform is configured to enable, when least part of the target analytes are bound to the immobilized biorecognition material, fluorescent markers associated with the bound target or other analytes to be excited by the evanescent field so as to emit fluorescence detectable by a detector. | 01-13-2011 |
20110020178 | ASSAY APPARATUSES, METHODS AND REAGENTS - We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring. | 01-27-2011 |
20110091355 | APPARATUS FOR CHEMILUMINESCENT ASSAY AND DETECTION - An apparatus includes a system for guiding chemiluminescence and a system for preventing a variation in dark currents. The apparatus includes a first light shielding BOX having a sample container holder and a shutter unit therein, the shutter unit including a top plate which is partly formed by a movement of a plate member, and a second light shielding BOX having a photodetector therein. While a measurement is not implemented, the shutter unit is closed to block entrance of stray light to the photodetector, and while a measurement is implemented, the plate member is moved to open the shutter unit, and the tip of the photodetector is inserted into a through hole formed in the top plate, so that the distance between the bottom of the sample container and a sensitive area of the photodetector is reduced to several millimeters or less. | 04-21-2011 |
20110171066 | Chemochromic Detector for Sensing Gas Leakage and Process for Producing the Same - A chemochromic sensor for detecting a combustible gas, such as hydrogen, includes a chemochromic pigment mechanically mixed with a polymer and formed into a rigid or pliable material. In a preferred embodiment, the chemochromic detector includes aerogel material. The detector is robust and easily modifiable for a variety of applications and environmental conditions, such as atmospheres of inert gas, hydrogen gas, or mixtures of gases, or in environments that have variable temperature, including high temperatures such as above 100° C. and low temperatures such as below −196° C. | 07-14-2011 |
20110171067 | GAS SENSITIVE STRUCTURE AND COMPONENT INCLUDING THE SAME - A component of a system configured to monitor one or more gaseous analytes. In one embodiment, the component comprises a conduit and a gas sensitive film. The conduit is formed to enable a flow of gas therethrough. The gas sensitive film is disposed in communication with the flow of gas, and is sensitive to one or more gaseous analytes within the flow of gas. In some instances, the film comprises a dye and a polymer matrix. The dye is sensitive to the one or more gaseous analytes. The polymer matrix carries the dye, is porous, and is formed such that the film has (i) a dynamic range of at least from about 20% to about 90% concentration of the one or more gaseous analytes, and (ii) a response time over at least a portion of the dynamic range of less than about 80 milliseconds. | 07-14-2011 |
20110176962 | QUANTUM DOT-BASED ENVIRONMENTAL INDICATORS - A detection method and indicator are disclosed that includes quantum dots that fluoresce under illumination of a first light having a first wavelength to indicate the presence of a predetermined condition, and in particular, a corrosion condition. The quantum dots are surrounded by a shell material that under normal conditions reflect the first light and reacts in the presence of the predetermined condition to permit the first light to illuminate the quantum dot to excite the quantum dot to emit a second light having a second wavelength, which when detected, indicates the presence of the predetermined condition. | 07-21-2011 |
20110206556 | METHOD OF DETECTING RESIDUAL DETERGENT AND DEVICE FOR DETECTING RESIDUAL DETERGENT - It is intended to provide a method whereby residual detergent (surfactant) can be conveniently and accurately detected in the step of washing or rinsing dishes or clothes, and a test device usable in examining the rinsed conditions. Namely, a method characterized by comprising bringing a test substance with a composition (test agent) comprising an oxalic acid ester, a fluorescent substance, hydrogen peroxide and a strong acid and thus easily detecting the residual detergent sticking to the surface of the test subject from the chemiluminescence thus caused; and a test device which is most suitable for storing the test agent as described above. | 08-25-2011 |
20110236258 | MEDICAL FLUID ACCESS DEVICE WITH ANTISEPTIC INDICATOR - A medical device, such as a vascular access device, is disclosed for providing access to a medical fluid flow path for the introduction or withdrawal of medical fluids to and from the flow path. The access device includes an indicator for providing a visual indication when the access device has been exposed to an antiseptic agent. | 09-29-2011 |
20110243790 | MICROFLUIDIC DEVICE FOR COUNTING BIOLOGICAL PARTICLES - A particle counter for analyzing blood has features which provide for automatic operation and preferably, also provide for portable use in a low resource setting. In a preferred embodiment, preferred embodiment, the device is used to obtain CD4 counts for AIDS diagnosis. | 10-06-2011 |
20110293473 | AUTOMATIC ANALYZER - An analytic method uses a labeled antigen, labeled antibody, tracer, etc. in which a radio isotope, fluorescent dye, luminescent dye, enzyme, etc. is bonded to an antibody or an antigen bonded to a protein as an object of analysis for performing an assay of a trace amount of a substance such as a hormone, tumor marker, infective pathogen marker, infective antibody, etc., for blood, serum, plasma, or body fluid as a sample or specimen. The analysis is enabled at high sensitivity, with less generation of noises and at low background. When an assay is performed based on the antigen-antibody reaction for a sample in an analytic method by fluorometry or luminometry, detection or measurement of non-specific fluorescence or luminescence such as interference light is eliminated or removed effectively irrespective of the property of the sample or the level of the concentration of substances contained in the sample. | 12-01-2011 |
20120014835 | OPTICAL SYSTEM FOR CHEMICAL AND/OR BIOCHEMICAL REACTIONS - An apparatus for detecting spectra in light emanating from chemical or biochemical reactions occurring in at least one reaction vessel ( | 01-19-2012 |
20120027642 | Luminometer or Fluorometer with an Injection Device - Described is a luminometer or fluorometer having an optical axis which extends essentially perpendicular to the measuring sample. The detector for the luminometer or the fluorometer is arranged either directly or via a deflection means in the optical axis. An injection device ( | 02-02-2012 |
20120114525 | AUTOMATIC ANALYZER - Photomultiplier tubes differ in performance between individual products, and deteriorate over time. To appropriately use a nonlinear calibration curve, it is desirable that changes in signal level be strictly equalized. This invention includes means for, prior to sensitivity adjustment of a photomultiplier tube by application of high voltages, measuring a same sample under a plurality of high-voltage conditions, determining, from linear relationships between logarithms of each high voltage and those of signal levels, an optimal voltage for a measuring operation of predetermined order of execution in the plurality of measuring operations, and recording identification information for identifying each linear relationship; the invention assessing a healthiness level of the photomultiplier tube by assessing the linear relationship. | 05-10-2012 |
20120177534 | CHEMILUMINESCENT DEVICE WITH TIME DELAY ACTIVATION - A throwable chemiluminescent device comprising a time-delay mechanism, wherein an oxalate component and a peroxide component are contained within the device. Certain embodiments are directed to a chemiluminescent device comprising a time-delay mechanism comprising at least two ampoules and an enclosure for the time-delay mechanism, wherein an oxalate component is contained in one of the at least two ampoules, and a peroxide component is contained in another of the at least two ampoules, and wherein the time-delay mechanism delays the chemiluminescent reaction of the oxalate component and the peroxide component. | 07-12-2012 |
20130052080 | AUTOMATIC ANALYZER - The automatic analyzer detects a trace amount of reaction solution at a high S/N with stability. The analyzer allows a photomultiplier to detect light from the reaction solution containing a luminescent substance through an optical window. To process the output from the photomultiplier to analyze the amount of the luminescent substance contained in the reaction solution, an optical transmission system is interposed between the optical window and the photomultiplier. The optical transmission system includes a light inlet opposed to the optical window; a light outlet opposed to the light-receiving surface of the detector; and a reflector on which an incident beam of light from the light inlet is reflected to propagate to the light outlet. This configuration allows the effects of temperature-dependent noise from a flow cell to be reduced while preventing a drop in the amount of light from the luminescent substance, thereby implementing analysis at a high S/N. | 02-28-2013 |
20130136656 | EXHAUST GAS MEASUREMENT DEVICE AND RECORDING MEDIUM HAVING PROGRAM FOR EXHAUST GAS MEASUREMENT DEVICE RECORDED THEREON - An exhaust gas measurement device includes a pressure regulator for keeping a pressure of sample gas in a sensor flow line or a bypass flow line to be a set pressure value, a flow rate sensor provided on the bypass flow line for measuring a flow rate of the sample gas flowing through the bypass flow line, and an attention attracting part for displaying that the flow rate of the sample gas is reduced in the case where the flow rate measurement value measured by the flow rate sensor becomes equal to or smaller than an attention attracting flow rate value larger than a pressure controlling limit flow rate value by a predetermined value, the pressure controlling limit flow rate value being a lower limit flow rate value that is pressure-controllable by the pressure regulator. | 05-30-2013 |
20130156642 | Optical detection system, a cartridge therefor and a reader therefor - A optical detection system for used as a bio sensor is disclosed, comprising a card or cartridge and a reader. The cartridge comprises at least a detection chamber and an optical detector, and the reader includes means to urge a fluid into the detection chamber to initiate the analysis. The optical coupling may be enhanced by including optical elements in the card; conversely the system may be simplified by reducing or eliminating the number of moving parts in the card. | 06-20-2013 |
20130183197 | CHEMILUMINESCENT SYSTEM - A chemiluminescent system includes a substrate comprising a solid chemiluminescent oxalate and a solution comprising an oxygen-providing compound. The chemiluminescent system provides improved light-output characteristics. | 07-18-2013 |
20130315780 | DIAGNOSTIC SYSTEMS AND INSTRUMENTS - Provided is a clinical diagnostic system that comprises a diagnostic instrument and a disposable cartridge. The diagnostic system can be used to measure assays in point of care clinical settings. | 11-28-2013 |
20140079591 | SPECIMEN ANALYZER - A specimen analyzer comprises a measurement mechanism section configured to measure a specimen by using a first consumable and a second consumable having a shape different from a shape of the first consumable, a first inlet for loading the first consumable, a supplying section configured to supply the first consumable loaded through the first inlet, to the measurement mechanism section, a sorter configured to sort the first consumable and the second consumable from each other, and a storage for housing the second consumable sorted by the sorter. | 03-20-2014 |
20140119993 | CHEMILUMINESCENT DETECTOR HAVING COATING TO REDUCE EXCITED SPECIES ADSORPTION - An apparatus for receiving a chemical species is disclosed. The apparatus includes an emission block configured to receive a vapor phase chemical species that is excited by chemical reaction in the emission block to provide an excited species that emits hot. The emission block has an interior portion having a surface. A coating is disposed over the surface and the coating reduces adsorption of the excited species onto the surface. | 05-01-2014 |
20140186212 | METHODS AND APPARATUS FOR MEASURING LUMINESCENCE AND ABSORBANCE - An automated chemistry analyzer includes a first fiber optic bundle that is used to guide a signal. The automated chemistry analyzer also includes a photomultiplier detector tube (PMT) that receives the guided signal from the first fiber optic bundle and produces an output PMT signal. The output PMT signal is used by the automated chemistry analyzer to derive chemi-luminescence and absorbance. | 07-03-2014 |
20150125345 | DEVICE FOR DETERMINING THE CONCENTRATION OF AT LEAST ONE GAS IN A SAMPLE GAS STREAM - A device for determining a concentration of at least one gas in a sample gas stream includes an analysis chamber, a detector, and a connecting channel. The analysis chamber is configured to have the sample gas stream and a reaction gas stream be introduced therein. The sample gas stream and the reaction gas stream are mixed to a gas mixture which reacts so as to emit an optical radiation. The detector is configured to measure the optical radiation. The connecting channel is configured to connect the analysis chamber to the detector. The connecting channel is configured as a light conductor extending from the analysis chamber to the detector. | 05-07-2015 |
20160061831 | AUTOMATIC ANALYSIS DEVICE - An analyzing device of the present invention is provided with a flow chamber that a fluid including magnetic particles associated with a labeling substance flows from a fluid inlet to a fluid outlet, magnetic trap means to apply a magnetic field for trapping the magnetic particles to the fluid in the flow chamber, a working electrode and a counter electrode to apply a voltage to the magnetic particles trapped by the magnetic trap means, and to emit a luminescence, a light detection element to detect a luminescence derived from the labeling substance on the magnetic particles trapped in the flow chamber, and regulating means to regulate a region that the light detection element detects the luminescence derived from the labeling substance on a part of magnetic particles of them trapped by the magnetic trap means. | 03-03-2016 |
20160153889 | IMAGING SYSTEM | 06-02-2016 |
20190143333 | LIQUID HEATER FOR USE IN ANALYZER | 05-16-2019 |