| Entries |
| Document | Title | Date |
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| 20080239304 | Apparatus and Methods for Analyzing Samples - The present invention relates to apparatus, systems, and methods for analyzing biological samples. The apparatus, systems, and methods can involve using a vacuum source to pull microfluidic volumes through analytical equipment, such as flow cells and the like. Additionally, the invention involves using optical equipment in conjunction with the analytical equipment to analyze samples and control the operation thereof. | 10-02-2008 |
| 20080252881 | HIGH-PRESSURE CROSS-POLAR MICROSCOPY CELLS HAVING ADJUSTABLE FLUID PASSAGE AND METHODS OF USE - Apparatus and methods are described for observing samples at non-ambient temperatures and pressures. One apparatus comprises a cell body having a fluid flow-through passage and a light passage intersecting the fluid flow-through passage at an adjustable light pathlength fluid analysis region; first and second light-transmissive windows in the light passage, each window having at least one crystal axis aligned longitudinally with a longitudinal axis of the window, the windows having opposed, spaced apart, substantially flat surfaces defining the adjustable light pathlength fluid analysis region, the first window having a first window holder and the second window having a second window holder, the first window rotationally isolated from the first window holder, the second window rotationally coupled to the second window holder, the first window holder able to gradually move the first window and thus adjust the light pathlength; and first and second light polarization filters. | 10-16-2008 |
| 20090009756 | Recognition Chip for Target Substance, and Detection Method and Device for the Same - A detection device comprising a substrate comprising a plurality of objects of which properties are changed due to the contact with a target substance, means for bringing the target substance into contact with the objects, and means for detecting a change in properties of the objects caused when the target substance is brought into contact with the objects, based on light output when the objects are irradiated with light, wherein the plurality of the objects are located in the direction in which the light for irradiation travels, and the detecting means is means for detecting the change in the properties based on the summation of light output from the plurality of the objects upon irradiation with light. | 01-08-2009 |
| 20090009757 | Cuvette - The present invention is to present a cuvette that is able to prevent a liquid splash and dispersion within the cuvette. The cuvette comprises: a body which is essentially cylindrical and has an opening at an upper end; and a bottom part which has a concave inner surface and is connected to a lower end of the body, wherein the inner surface of the bottom part comprises a tapered part whose inner diameter linearly decreases toward a bottom of the cuvette. | 01-08-2009 |
| 20090009758 | OPAQUE ADDITIVE TO BLOCK STRAY LIGHT IN TEFLON AF LIGHT-GUIDING FLOWCELLS - The present invention is directed to the use of a light absorbing wall material to eliminate stray light paths in light-guiding structures, such as those used for HPLC absorbance detection. More specifically, the present invention relates to the use of carbon-doped Teflon® AF, or “black Teflon® AF,” for all or part of the walls of a light-guiding flowcell adapted for use in HPLC absorbance detection. | 01-08-2009 |
| 20090021729 | Photoelectric Smoke Detector - A photoelectric smoke detector is provided which is suitable for being downsized without detection capability deterioration. The present invention relates to a photoelectric smoke detector for detecting presence of smoke by utilizing a light emitting element and a light receiving element whose optical axes intersect with each other. Then the photoelectric smoke detector has: a specialized labyrinth function fulfilling part for playing only a labyrinth function of bringing air flow into an interior space thereof and preventing entry of disturbance light into the interior space; and a smoke detecting part which is provided above the specialized labyrinth function fulfilling part so that an interior space of the smoke detecting part is communicated with the interior space of the specialized labyrinth function fulfilling part, and which has the light emitting element and the light receiving element built therein and has a small hole for extracting air flow that has passed through a detection area near an intersection between the optical axes of the light emitting element and the light receiving element. | 01-22-2009 |
| 20090027666 | System and method for flow cytometry - A flow cytometry system and related method, among other things, are disclosed. In at least one embodiment, the system includes first, second, and intermediate slab formations, the last of which has formed therewithin a microfluidic channel, a lens structure arranged proximate the microfluidic channel, and a light conveying structure arranged proximate to the lens structure. The lens structure is configured to direct a portion of light to proceed between the channel and the conveying structure. The intermediate slab formation is sandwiched between the other two slab formations. In at least another embodiment, the system includes a microfluidic prism arranged proximate to the second end of a light conveying structure. Light emanating from a microfluidic channel is provided to the conveying structure at the first end, conveyed to the second end, and provided to the prism, which outputs a plurality of portions of the light at different frequencies in different directions. | 01-29-2009 |
| 20090040515 | Formats For Optical Analysis And Methods Of Manufacturing The Same - Formats for the optical testing of fluids are manufacturing using modular format components. The format components are constructed so that matching format components can be mated together to form a single format for optical testing. Formats may be manufactured using pin-and-hole construction so that pins on optical format components mate with holes on opposing format components. Optical read surfaces provided on optical format components oppose each other in a completed optical format to form a read area. | 02-12-2009 |
| 20090046282 | Flowthrough Cell of the Flowing Spectrophotomatic Analysis - In the invention, the transparent tube is used as the fluid pathway of the flowthrough cell, which not only makes sure the fluid can retain the stable laminar state and no micro-bubble existing, but also can avoid the turbulent and the micro-bubble producing the negative peak and the interference peak. Utilizing the transparent property of the pipe wall, the ektexine of both ends of the optical pathway is made to be a smooth plane and forms a single unit planar light inlet window with the pipe. There do not need to be furnished with the glass window or the quartz glass window any more. This smart design has solved the leakage and dead angle problem that has puzzled people for a long term. The invention not only simplifies the structure but also increases the precision. It produces an unexpected research finding. | 02-19-2009 |
| 20090051912 | Modular Microfluidic Flow Cytometer and Method Applications - An embodiment of the invention is directed to a portable, modular, microscope mounted, microfluidic flow cytometry system. The system includes a microscope platform having an optical input/output port, imaging optics, and a sample stage; a sample illumination source module that is removably integrated with the optical input/output port; an optics module that is removably integrated with the sample excitation light source module and the optical input/output port; a detector module that is removably integrated with the optics module and the optical input/output port; a fluidic pump module having a fluidic input and a fluidic output, a first removable fluid conduit for connecting a fluid source to the input, and a second removable fluid conduit for connecting the output to an input of a microfluidic flow module; and, a system control and programmable data processing module. The system may further incorporate a microfluidic flow module positionable on the microscope sample stage having an output removably connectable to a fluidic waste collector. Method embodiments relating to applications of the microscope-mounted microfluidic flow cytometry system are also described. | 02-26-2009 |
| 20090051913 | SENSOR DEVICE - A sensor device for detecting a substance contained in a fluid comprises first and second photonic crystal regions, first and second flow channels, an optical waveguide connected to the first and second photonic crystal regions and an optical detector for detecting the lights transmitted through the first photonic crystal region and the waveguide and transmitted through or reflected by the second photonic crystal region. | 02-26-2009 |
| 20090079976 | Photonic crystal sensors with integrated fluid containment structure, sample handling devices incorporating same, and uses thereof for biomolecular interaction analysis - Photonic crystal (PC) sensors, and sensor arrays and sensing systems incorporating PC sensors are described which have integrated fluid containment and/or fluid handling structures. The PC sensors are further integrated into a sample handling device such as a microwell plate. Sensors and sensing systems of the present disclosure are capable of high throughput sensing of analytes in fluid samples, bulk refractive index detection, and label-free detection of a range of molecules, including biomolecules and therapeutic candidates. The present disclosure also provides a commercially attractive fabrication platform for making photonic crystal sensors and systems wherein an integrated fluid containment structure and a photonic crystal structure are fabricated in a single molding or imprinting processing step amendable to high throughput processing. | 03-26-2009 |
| 20090086198 | Micro Cuvette Assembly and Use Thereof - Relates to a micro cuvette assembly ( | 04-02-2009 |
| 20090116005 | FINE PARTICLE MEASURING METHOD, SUBSTRATE FOR MEASUREMENT, AND MEASURING APPARATUS - A fine particle measuring method of performing optical measurement of fine particles introduced into a plurality of sample fluidic channels provided at predetermined distances on a substrate by scanning light to the sample fluidic channels is disclosed. The method includes: sequentially irradiating the light to at least two or more reference regions provided together with the sample fluidic channels; detecting a change of optical property occurring in the light due to the reference regions; and controlling timing of emission of the light to the sample fluidic channels. | 05-07-2009 |
| 20090135415 | Optical Cavity for Gas Sensor - An optical cavity for a Non-Dispersive Infrared gas sensor has invented comprising two oppositely arranged parabolic mirrors having common focus located on the common optical axis of the parabolic mirrors, and a plane mirror arranged along the optical axis between the vertex of each of the parabolic mirrors. The NDIR gas sensor has an extended optical path to increase precision and accuracy in the measurement, and substantially increased ventilation opening size to facilitate in and out of the target gas through the optical cavity thereby decreasing the response time required for measuring the gas concentration. The sensors based on the principal of Non-Dispersive Infrared Detection is used the light-absorbing characteristic of gases to measure the amount of light absorption that occur at the specific wavelength absorbed by a target gas and calculate the target gas concentration. | 05-28-2009 |
| 20090147253 | MICROFLUIDIC CHIP APPARATUSES, SYSTEMS AND METHODS HAVING FLUIDIC AND FIBER OPTIC INTERCONNECTIONS - Microfluidic Chip Apparatuses, Systems, and Methods having Fluidic and Fiber Optic Interconnections. According to one embodiment, apparatuses and methods are provided for connecting a light-guiding conduit to a microfluidic channel. First and second substrates with first surfaces can be provided, wherein the first surfaces of the first and second substrates form a microfluidic channel and a connection channel when the first surfaces are positioned together, and wherein the connection channel extends from an edge of the first surface of the first or second substrate to the microfluidic channel. The apparatus and method can also include bonding the first surfaces of the first and second substrates to form the microfluidic channel and the connection channel. A light-guiding conduit can be inserted into the connection channel such that the light-guiding conduit connects to the microfluidic channel and filling an area between the light-guiding conduit and the connection channel for forming a liquid-tight seal between the light-guiding conduit and the connection channel. | 06-11-2009 |
| 20090153851 | CUVETTE AND METHOD FOR USING THE CUVETTE - A cuvette with at least one sealing element and two transparent elements is provided where the latter are arranged at a distance from one another and define two opposing boundary faces of a sample channel and the sealing element defines side walls of the sample channel as a result of which the sample channel is formed as a channel that is closed in the longitudinal direction with an inlet opening and an outlet opening. At least one spacer is provided which keeps the transparent elements at a distance from one another. At least one of the two transparent elements has a projection which extends towards the other transparent element and forms a boundary surface of the sample channel such that the height of the sample channel is less than the height of the at least one spacer. | 06-18-2009 |
| 20090174881 | OPTICAL SYSTEM FOR A FLOW CYTOMETER WITH AN INTERROGATION ZONE - The optical system of the preferred embodiments includes a first light source that creates a first beam of a first wavelength, a first collimating element that collimates the first beam, a second light source | 07-09-2009 |
| 20090231576 | Method and Apparatus for Centering an Ophthalmic Lens - An ophthalmic lens (CL), e.g. a contact lens, is centered in a concave trough ( | 09-17-2009 |
| 20090237655 | APPARATUS FOR POSITIONING A CUVETTE IN AN OPTICAL BEAM PATH OF AN OPTICAL MEASURING INSTRUMENT - An apparatus for positioning a cuvette in an optical beam path of an optical measuring instrument, with a shaft for axially inserting a cuvette, and means for pressing a cuvette against at least one wall surface of the shaft, which comprise at least one arrangement of a magnet, stationarily arranged with respect to the shaft, and a magnet movable with respect to the same, which are oriented such that the movable magnet tends to occupy a certain position with respect to the stationary magnet, in which the movable magnet engages at least partially into the shaft. | 09-24-2009 |
| 20090257054 | COMPACT, THERMALLY STABLE FIBER-OPTIC ARRAY MOUNTABLE TO FLOW CELL - Various embodiments of an optical system for directing light for optical measurements such laser-induced fluorescence and spectroscopic analysis are disclosed. In some embodiments, the optical system includes a thermally conductive housing and a thermoelectric controller, a plurality of optical fibers, and one or more optical elements to direct light emitted by the optical fibers to illuminate a flow cell. The housing is configured to attach to a flow cell. | 10-15-2009 |
| 20090262343 | INFRARED SPECTROSCOPY OF MEDIA, INCLUDING AQUEOUS - Wide band infrared spectroscopy of molecules in a variety of media is provided by apparatuses, materials and methods that allow real time spectroscopic view of molecules such as proteins in native environments. Precisely machined sample holders and algorithms are used to reduce spectroscopic effects of solvents such as water. Multiple samples can be analyzed simultaneously. Embodiments provide secondary and tertiary structure information of substances such as proteins based on molecular interactions that can be monitored and manipulated in real time. | 10-22-2009 |
| 20090296083 | OPTICAL ASSAY APPARATUS AND METHODS - Optical assay apparatus and methods are provided having an optical assay cup for detecting analytes in a sample fluid. The cup's sidewall may include an optical waveguide having a detection coating on its inner surface. During use, the waveguide receives evanescent or darkfield interrogation light, interrogates at least part of cup's interior volume with it, and emits signal light as a function of the analytes. The detection coating may have fluid or non-fluid detection layers, at least part of which may form at least part of a waveguide for the interrogation light. The cup may be spun during use, such as to centrifugally-concentrate any high-density analytes towards cup's sidewall. The assay apparatus may further include an interrogation light source, a cover or spinning apparatus for the cup, and an optical detector for the signal light. | 12-03-2009 |
| 20100026999 | METHODS OF MAKING AND USING AND APPARATUS AND DEVICES FOR PLACING LIGHT AND SAMPLE IN PHOTO-EMITTING OR ABSORBING DEVICES - The present invention relates to apparatus and devices ( | 02-04-2010 |
| 20100060892 | FLOW SCHEMES FOR ENHANCED LIGHT-TARGET INTERACTION IN FLUIDIC CHANNELS - An embodiment is a fluidic channel to enhance light-target interaction. A first channel portion receives a first excitation light, an analyte flow, and a sheath flow. The analyte flow and the first excitation light are separated while in the first channel portion. The sheath flow flows on two sides or surrounds the analyte flow. A second channel portion has a first redirection structure to redirect the analyte flow by the sheath flow into the first excitation light at a first detection area. | 03-11-2010 |
| 20100073673 | CLOSED CELL FOR USE IN SPECTROPHOTOMETERS - A closed cell (1) for use in spectrophotometers, adapted to receive a liquid to be subjected to analysis and an air space or bubble to absorb pressure differentials, wherein the cell (1) includes means to retain the air space or bubble in a predetermined location in the cell. | 03-25-2010 |
| 20100079749 | Inspection apparatus for biological sample - An inspection apparatus for a biological sample is herein disclosed, wherein a sample, entering a communicating space via a first opening, is sucked upward to a test area by capillarity and then sucked downward to a second opening by a siphonic action; then the sample becomes still as a result of the communicating tube principle. Hence, the present invention provides sufficient amount of biological sample for the test area and also simplifies the inspection process. | 04-01-2010 |
| 20100103410 | DEVICES AND METHODS FOR VISUALIZATION OF A SAMPLE IN A MICROPLATE - Disclosed herein is a microplate comprising a plurality of wells and methods and systems comprising such microplates, wherein an individual well comprises an opaque or non-transparent surface at or near the bottom of the well. The microplates herein can provide improved visualization of the process of filling a well with a liquid reagent. The microplates can be configured to perform chemical analysis, such as polymerase chain reaction (PCR) or nucleic acid detection. | 04-29-2010 |
| 20100118298 | FLOW CELL FOR A FLOW CYTOMETER SYSTEM - The flow cytometer system of the preferred embodiment includes a flow cell body that functions to contain, protect, and align the components of the flow cytometer system; a flow channel, coupled to the flow cell body, that functions to conduct and focus sample fluid through an interrogation zone; and a sample injection probe, removably coupled to the flow cell body, that functions to provide a uniform flow of sample fluid to the flow channel. The flow cytometer system is preferably designed for the flow cytometer field. The flow cytometer system, however, may be alternatively used in any suitable environment and for any suitable reason. | 05-13-2010 |
| 20100141938 | METHOD AND APPARATUS FOR DETECTION OF ANALYTES - A microfluidic detection system is provided. The system comprises a device for illuminating a microfluidic sample comprising an analyte, wherein illumination from the illuminating device is modulated on and off at a determined frequency, a gated phase-sensitive detector that detects, one or more wavelengths emitting from the analyte, at a determined frequency, and a control device that coordinates the modulating frequency of the illumination and the detecting frequency of the detector. | 06-10-2010 |
| 20100177305 | CUVETTE FOR FLOW-TYPE PARTICLE ANALYZER - The present invention provides an optical cuvette for use in a flow-type particle analyzer, wherein the cuvette includes a removable flow tube containing a flow channel oriented coaxially. | 07-15-2010 |
| 20100182597 | METHOD AND DEVICE FOR PRODUCING A CUVETTE AND CUVETTE PRODUCED USING SAID METHOD - A multi-part injection mold ( | 07-22-2010 |
| 20100220322 | Cells for biochemical analysis, kit for biochemical analysis, and biochemical analyzer - The invention makes it possible to measure binding of a biochemical substance with a high throughput and with high sensitivity using a small cell capable of being filled with a small amount of chemical solution. A space between a first substrate and a second substrate such that probes are immobilized on their mutually facing planes is used as a cell that houses a specimen solution. Light is irradiated from a first substrate side, and reflected light is subjected to spectroscopy. Binding of the target with the probe is detected by a wavelength shift in the refection spectrum. | 09-02-2010 |
| 20100231903 | Microbubble optical resonator - An optical microresonator is configured as an optical microbubble formed along a section of an optical microcapillary. The curvature of the outer surface of the microbubble creates an optical resonator with a geometry that encourages the circulating WGMs to remain confined in the central region of the bubble, creating a high Q optical resonator. The resonator may be tuned by modifying the physical properties of the microbubble, allowing the resonator to be used as an optical filter. The resonator may also be used as a sensor or laser by introducing the material to be sensed (or the active laser material) into the microcapillary along which the microbubble is formed. | 09-16-2010 |
| 20100238436 | CUVETTE - A cuvette is shaped cylindrically at one end in order to be placed in a standard microfuge and is designed to specifically remove unwanted contaminates by centrifugation. The lower part of the cuvette is shaped substantially smaller to collect liquids for direct analysis and has a shape that will conform to a variety of spectrophotometers for the measurement of the absorption of irradiation and at times the subsequent scattering of light from the liquid samples which at least in the regions of the windows or desired shape is of a transparent plastic or glass with an inner space. The upper opening of the cuvette is for filling and removing sample fluid and sample preparation in a centrifuge and the lower part projects downwards towards the floor of the measuring chamber and which comprises a smaller cross section than the upper part. A cuvette holder is designed to conform to the shape of the cuvette with an outer surface to conform to the specific measuring device. | 09-23-2010 |
| 20100245815 | CENTRIFUGAL DEVICE - A device consisting of a rotatable substrate ( | 09-30-2010 |
| 20100290041 | Monolithic Optical Flow Cells and Method of Manufacture - An improved optical flow cell adapted for use in a flow cytometer for differentiating formed bodies (e.g., blood cells). Manufactured from a monolithic transparent material, the improved flow cell has an internal flow channel of polygonal transverse cross-section through which prepared samples can be metered and an external envelope suited to acquisition of optical parameters from formed bodies in such samples. Preferably, such flow cell is formed by a glass-drawing process in which a relatively large glass preform having a rectilinear internal channel of a desired polygonal cross-sectional shape is heated and drawn to achieve a desired cross-sectional area of reduced size. Also disclosed are preferred methods for differentiating formed bodies using the flow cell of the invention. | 11-18-2010 |
| 20100302534 | SAMPLE OBSERVATION SYSTEM AND SAMPLE OBSERVATION PROCESS - A sample observation system and a sample observation process are provided which do not need any special manipulation or treatment to limit the motion of the sample or adjust the orientation of the sample when observing the sample, and enable observation of samples simply from wider direction than ever. A sample observation system of a sample whose vertical direction is defined by gravity, wherein the system at least includes a sample holder having at least one penetrating hole for retaining a liquid containing the sample; an observation unit for observing the sample; and an angle adjusting unit for varying the angle of the observation unit to the direction of the gravity which acts on the sample in a condition in which the sample holder and the observation unit have a fixed relative angle therebetween. | 12-02-2010 |
| 20110013183 | Method of Using a Flow Cell Apparatus for Visualizing Additive Deposition on a Substrate - A method of visualizing the deposition of an additive from a personal care composition onto substrates such as hair, skin mimic and fabric through the use of a flow cell device. | 01-20-2011 |
| 20110051133 | Clinical laboratory test apparatus - A clinical laboratory testing apparatus comprises a microchip for holding a sample liquid; a rotation body for rotating the microchip; a rotation drive mechanism; a lock mechanism for locking the microchip on the rotation body; a measurement room that holds the microchip and the rotation body; a protection cover; a light source that irradiates the measuring cell of the microchip; and a light receiving unit, wherein a centrifugal separation processing of a specimen in the sample liquid is performed in the microchip. | 03-03-2011 |
| 20110058163 | Optical system for a flow cytometer with an interrogation zone - The optical system of the preferred embodiments includes a first light source that creates a first beam of a first wavelength, a first collimating element that collimates the first beam, a second light source | 03-10-2011 |
| 20110134420 | Microchip and Analyzing Apparatus - The present invention relates to a microchip | 06-09-2011 |
| 20110141465 | Light-Guiding Flow Cells And Analytical Devices Using The Same - A flow cell for a photometric device includes a module having a body with a distal face defining an annular channel. The body also defines an axial central passage and an axial flow channel. A second module has a body with a proximal face defining an annular channel. The second body also defines an axial flow channel in fluid communication with the first axial flow channel. A light guiding member is within the central passage for exposing a fluid in the flow channels of the modules. An assembly seals an interface between the distal and proximal faces such that the fluid does not leak from the flow channels. The assembly has a metal gasket between the distal and proximal faces, the metal gasket defining a flow path between the flow channels, a first sealing member in the first annular channel and a second sealing member in the second annular channel. | 06-16-2011 |
| 20110164245 | Cuvette, Insert, Adapter and Method for Optically Examining Small Amounts of Liquid - A cuvette comprising at least one insert with two measuring surfaces, wherein the insert is a measurement tip, which has the two measuring surfaces on one end, which is distanced from another end of the measuring tip, and an adapter for insertion in a cuvette shaft of an optical measuring device and means of insert and adapter for releasably holding the at least one insert in the adapter with the measuring surfaces at a separation distance from each other for the positioning of a sample between the measuring surfaces in a beam path of the optical measuring device passing through the cuvette shaft. | 07-07-2011 |
| 20110170094 | Cuvette, Insert, Adapter and Method for Optically Examining Small Amounts of Liquid - Cuvette, comprising at least one measuring area on each one of two arms that are pivotally connected to each other such that from a swung-apart condition, they can be swung together into a measuring position in which the two measuring areas have a distance for positioning a sample between the measuring areas, and means for positioning the two arms in a measuring position in a cuvette shaft of an optical measuring device with a sample between the two measuring areas in a beam path of the optical measuring device that crosses the cuvette shaft. | 07-14-2011 |
| 20110181875 | SAMPLE STORAGE - Provide a sample storage, in which barcodes and two-dimensional codes printed on the outer surface of the sample storage can be read correctly without false recognition. A storage tube | 07-28-2011 |
| 20110194104 | Device and method for optical parallel analysis of a sample arrangement and corresponding manufacturing method - A device and a method for optical parallel analysis of a sample arrangement. The device includes a system of sample areas provided on and/or in a front face of the carrier substrate for receiving a sample substance; a system of detector areas provided on and/or in a back face of the carrier substrate, each detector area being assigned to a corresponding sample area; and a system of optical devices, each optical system being assigned to a corresponding sample area and being designed in such a way that it deflects light beams, which the corresponding sample area in response to an optical excitation does not emit in the direction of a detector area assigned to it, in the direction of the detector area assigned to it and/or in the direction of a detector-free area on the back face of the carrier substrate. | 08-11-2011 |
| 20110255084 | BIO-SAMPLE IMAGE PICKUP DEVICE - A bio-sample image pickup device includes a light source module, a carrier, an image pickup unit, a first filter set, and a second filter set. The carrier carries the light source module and the bio-sample, and moves between a first position and a second position. The first filter set between the light source module and the image pickup unit for filtering the light emitted by the light source module, and the image pickup unit picks up the image of the bio-sample through the first filter set in the first position. The second filter set in the second position filters the light emitted by the light source module for allowing an operator to see the bio-sample in the second position through the second filter. | 10-20-2011 |
| 20110285990 | ANALYSIS TOOL AND MICROANALYSIS SYSTEM - In a case of generating a main body of an analysis tool and a micro flow path chip as separate components, to obtain an accurate sample analysis result and to accurately adjust fluid temperature inside the micro flow path chip without damaging an analytical light receiving section of the micro flow path chip. In main body of analysis tool ( | 11-24-2011 |
| 20110292382 | SYSTEM AND METHOD FOR DETERMINING THE ASPHALTENE CONTENT OF CRUDE OIL - A system for determining the asphaltene content of crude oil includes a first optical flow cell, a first spectrometer operably associated with the first optical flow cell, and a mixer in fluid communication with the first optical flow cell. The system further includes a crude oil injection/metering device configured to receive the crude oil, the crude oil injection/metering device being in fluid communication with the first optical flow cell; a titrant injection/metering device in fluid communication with the mixer, the titrant injection/metering device configured to receive a titrant; and a filtration unit in fluid communication with the mixer. The system further includes a second optical flow cell in fluid communication with the filtration unit, and a second spectrometer operably associated with the second optical flow cell. | 12-01-2011 |
| 20110292383 | MICRO CUVETTE ASSEMBLY AND USE THEREOF - Micro cuvette assembly for examining biological samples has a first partial plate with one or more first cuvette surfaces and a second partial plate opposite the first and which also has one or more second cuvette surfaces. In an active position of the assembly, the second cuvette surfaces are arranged parallel and in register with the first cuvette surfaces and are spaced apart from the first cuvette surfaces whereby one or more micro cuvettes are formed. The first and second partial plates also have openings arranged in register with the cuvette surfaces and transparent bodies are provided as the cuvette surfaces. The first and second plates are completely penetrated by these openings and the transparent bodies are manufactured from a different material than the partial plates and span the openings close to a first surface of the partial plates. The first and second cuvette surfaces of a micro cuvette in the active position are wetted by a liquid volume which has previously been applied to one of the cuvette surfaces so that the liquid volume is held between these two cuvette surfaces. | 12-01-2011 |
| 20120033210 | OPTICAL DETECTION SYSTEM FOR MONITORING RTPCR REACTION - An optical detection system for monitoring real-time PCR reactions in a plurality of sample chambers with a plurality of optical units is provided. Due to a relative movement, the optical units are relative to the sample chambers, color multiplexing and space multiplexing are combined for optically detecting pathogens in a sample during the process of the PCR and delivering a quantitative result. | 02-09-2012 |
| 20120038914 | METHOD AND APPARATUS FOR SORTING CELLS - A method, apparatus, and system for a sorting flow cytometer include an objective lens having an optical axis coaxially aligned with the flow path at the focal point. A controllable energy source selectively alters an analyte according to a determination of whether the analyte is in a desired sub-population. In various embodiments, one or both of the emission from the controllable energy source and/or the emission from an illumination energy source passes through the objective lens. In some embodiments in which the emission from the controllable energy source passes through the objective lens, the objective lens may focus the emission from the controllable energy source at a different point than the focal point of a signal detected from the analyte and, in particular, at a point closer to the objective lens. | 02-16-2012 |
| 20120086938 | Analysis of an Acoustically Separated Liquid - An analyser is provided comprising a sample chamber for holding a liquid sample containing particles and an ultrasound source acoustically couplable to the sample chamber to supply resonant ultrasound energy for acoustically concentrating particles in the liquid sample in nodal planes established thereby. A probe is also provided which is adapted to supply electromagnetic energy into the sample chamber and to receive the supplied electromagnetic energy from the sample chamber at least during a time at which particles are substantially concentrated in associated nodal planes. The analyser is provided with an analysis unit in operable connection to a detector of the optical probe and is adapted to determine one or both a quantitative and a qualitative property of the liquid sample from the received electromagnetic energy. | 04-12-2012 |
| 20120092659 | MULTI-PARAMETER INTEGRATED CUVETTE POOL - The invention provides a multi-parameter integrated cuvette pool having a plurality of cuvette pool cells. Adjacent cuvette pool cells are connected to each other through a connecting plate. A heat generation unit is arranged in each cuvette pool cell. | 04-19-2012 |
| 20120105837 | Optical Cup - The present invention relates to a system for conducting the identification and quantification of micro-organisms, e.g., bacteria in biological samples. More particularly, the invention relates to a system comprising a disposable cartridge and an optical cup or cuvette having a tapered surface; wherein the walls are angled to allow for better coating and better striations of the light, an optics system including an optical reader and a thermal controller; an optical analyzer; a cooling system; and an improved spectrometer. The system may utilize the disposable cartridge in the sample processor and the optical cup or cuvette in the optical analyzer. | 05-03-2012 |
| 20120140213 | STATIC DESALTER SIMULATOR - A small-scale static simulator for crude oil refinery desalters has an oil bath, a portion of which is made of a transparent material, a heater/circulator configured to control the temperature of the oil bath and an emulsion-forming device. The desalter simulator also includes a plurality of mixing tubes, each mixing tube having a cap member with a blending assembly configured to work with the emulsion-forming device to emulsify an oil/water mixture contained in the mixing tube. A tube-holding rack is received in the oil bath. The tube-holding rack has a plurality of parallel plates, said plates having openings forming mixing tube receiving apertures. The desalter simulator includes at least one light source positioned adjacent to the oil bath, wherein the light source comprises an under light positioned beneath the oil bath configured to direct light into each of the mixing tubes located in the tube-holding rack, wherein the light source is directed through the transparent portion to aid in visualization and testing of the demulsification process. The desalter simulator also includes a power supply, wherein the plates of the tube-holding rack are connected to the power supply to form an electric grid adjacent the mixing tubes. | 06-07-2012 |
| 20120154799 | OPTICAL ANALYZER HAVING A HOLDER FOR INSTALLATION IN A GAS-CARRYING HOLLOW SPACE - An optical analyzer, in particular an optical gas analyzer, having a holder ( | 06-21-2012 |
| 20120182548 | NANOFLUIDIC CELL - A flow cell is provided for the analysis and/or microscopy of liquid or gas samples on the nanometer to micron scale. The flow cell preferably includes a thin membrane that is transparent to electrons and/or photons, thereby enabling the penetration of electrons or photons into a liquid flowing through the cell. Trenches are provided on either side of the membrane, which advantageously minimize fluidic resistance outside of the window area of the cell and also enable a faster response time in response to changes in external fluidic pressure. This feature enables active feedback using pathlength sensitive probes to stabilize the fluid flow to thin streams from nanometer to micron scale thicknesses with nanometer precision. | 07-19-2012 |
| 20120293797 | METHODS AND SYSTEMS FOR OPTICAL CHARACTERISATION - An optical device is described for irradiating at least one object in a medium. The optical device may be a microfluidics device, and comprises at least one integrated planar waveguide that enables providing sheet irradiation of objects in the medium. A characterization system including such an optical device and a corresponding method of characterizing an object or a fluid are described. | 11-22-2012 |
| 20120300200 | OPTICAL MEASUREMENT DEVICE - Optical measurement devices including one or more sealing assemblies are described. The sealing assemblies are configured for use at relatively high temperatures and pressures, such as temperatures over 200 degrees F. and pressures over 10,000 psi. The sealing assemblies can include a deformable seal element surrounded on each side by a backup seal element. In some examples, the deformable seal element is formed of a material selected from a group consisting of a fluoroelastomer or polytetrafluoroethylene, and the backup seal elements are formed of a material selected from a group consisting of flexible graphite or metal foil. Optionally, at least one additional seal element functioning as an extrusion barrier can be placed on the opposite side of one or both backup seal elements from the deformable seal element. The additional seal element can be formed of polyether ether ketone or flexible graphite, for example. Additional devices and assemblies are described. | 11-29-2012 |
| 20120320375 | Apparatus for Stabilizing Mechanical, Thermal, and Optical Properties and for Reducing the Fluorescence of Biological Samples for Optical Evaluation - An apparatus is presented for stabilizing an optical, thermal, and mechanical interface between a spectroscopic and/or imaging system and a biological sample. The apparatus includes a window retainer having a retainer surface and a well. The retainer surface surrounds the well. Further, the retainer surface is substantially planar. An optical window is located in the well. The optical window comprises a first and second surface. The second surface is in contact with the window retainer. The first surface is substantially flush with the retainer surface. The apparatus further includes an attachment mechanism coupling the window retainer to the biological sample such that a fluid, gel, adhesive or elastomer interposed between the optical window and the biological sample is trapped in the well. | 12-20-2012 |
| 20120327404 | FLEXIBLE SAMPLE CONTAINER - The invention relates to a system for holding a fluid sample, said system comprising a transparent flexible tube for holding said fluid sample, a tube holder for holding said tube, a first flattening element, and second flattening element, wherein said first flattening element and said second flattening element may be moved relative to each other thereby changing said transparent flexible tube from a first state to a second state, where at least a first cross sectional dimension of said tube is smaller in said second state than in said first state. | 12-27-2012 |
| 20130027695 | MICROFLUIDIC SYSTEMS WITH CHEMICAL PUMPS - A microfluidic system may include an image sensor integrated circuit containing image sensor pixels. A channel containing a fluid with particles such as cells may be formed on top of the image sensor. Flow control components may be mounted to the image sensor integrated circuit for controlling the flow of fluids through the channel. The flow control components may include a chemically powered pump. The chemical pump may include one or more chambers and a valve between the chambers. The valve may be operable to allow chemical reactants stored in the chambers to be mixed to produce gasses for generating pressure in the channel. The pressure in the channel may be used to control the flow of the fluid. As the fluid and particles flow through the channel, the image sensor pixels may be used to capture images of the particles. | 01-31-2013 |
| 20130050692 | PRESENTATION SYSTEM AND METHOD FOR LOW-VOLUME SOLUTION SAMPLES - A presentation system for a low-volume solution sample for use in an analysis system is provided. An adapter positions aliquots of the low-volume sample solution for measurement by the analysis system. The adapter includes a recess formed in an upper surface of the adapter for removable receipt of a sample holder that holds the aliquots of the low-volume sample solution. The sample holder is seated in the recess when the sample holder is inserted into the recess. The shape of the recess substantially conforms to at least a portion of the shape of the sample holder such that the recess maintains the sample holder in place during measurement of the aliquots. The recess also has a depth sufficient to receive the sample holder and a cover plate when the sample holder and the cover plate are inserted into the recess. | 02-28-2013 |
| 20130094019 | SAMPLE CARRIER WITH LIGHT REFRACTING STRUCTURES - The invention relates to a carrier ( | 04-18-2013 |
| 20130107251 | Multi-Cuvette Autosampler For Photo-Optical Measurements | 05-02-2013 |
| 20130114075 | BIOLOGIC FLUID SAMPLE ANALYSIS CARTRIDGE - A biological fluid sample analysis cartridge, analysis system, and method for analyzing a biologic fluid sample are provided. The cartridge includes a collection port, at least one channel within the cartridge in fluid communication with the collection port, a passage in fluid communication with the at least one channel, and an analysis chamber mounted on a tray. The tray is mounted relative to the cartridge and selectively positionable relative to the passage in a first position where the analysis chamber will engage a bolus of sample extending out from the passage to permit selective transfer of sample from the bolus to the analysis chamber. | 05-09-2013 |
| 20130114076 | CARTRIDGE WITH LARGE-SCALE MANUFACTURING DESIGN - The invention relates to a cartridge ( | 05-09-2013 |
| 20130120747 | CELL COUNTING AND SAMPLE CHAMBER AND METHODS OF FABRICATION - The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological sample. More particularly, the invention relates to a unique cell counting chamber, e.g., a thin gap fluidic cell chamber for both bright field and fluorescent imaging of bacteria or parasites, and methods for making the same. | 05-16-2013 |
| 20130242298 | PRISM PART OF ANALYSIS CHIP, ANALYSIS CHIP INCLUDING THE PRISM PART, AND METHOD FOR PRODUCING PRISM PART OF ANALYSIS CHIP - The invention relates to a prism part included in an analysis chip for use in an analysis device for analyzing a specimen utilizing surface plasmon resonance, and being cooperative with a channel member to form a channel for flowing a sample solution containing the specimen. The prism part includes a prism main body into which excitation light for generating surface plasmon is incident, and a gold film formed on a specified surface of the prism main body. The prism main body includes a mixed layer having a predetermined thickness from the specified surface toward the inner side. The mixed layer is formed by ions of gold for the gold film to enter from the specified surface in the formation of the gold film on the specified surface. | 09-19-2013 |
| 20130293881 | SELF-CLEANING OPTICAL SENSOR - An optical sensor may include a sensor head that has an optical window for directing light into a flow of fluid and/or receiving optical energy from the fluid. The optical sensor may also include a flow chamber that includes a housing defining a cavity into which the sensor head can be inserted. In some examples, the flow chamber includes an inlet port defining a flow nozzle that is configured to direct fluid entering the flow chamber against the optical window of the sensor head. In operation, the force of the incoming fluid impacting the optical window may prevent fouling materials from accumulating on the optical window. | 11-07-2013 |
| 20130335734 | Gas cell for the optical analysis of gases - A measuring cell for a gas analysis spectrometer has an inner chamber ( | 12-19-2013 |
| 20140055782 | FLOW CELL - A flow cell includes holding members for holding two ends of a capillary. A refractive index of holding members is 1.31 or less or 1.40 or greater at least in portions through which the holding members make contact with an outer surface of the capillary. A numerical aperture of light for measurement that enters from a light source into the capillary is 0.22 or less so that reflectance of portions through which the holding members make contact with the capillary is constant even when sample liquid that flows through the capillary is converted to water and acetonitrile. | 02-27-2014 |
| 20140063494 | FLOW CELL - In a flow cell, where a light introducing member for introducing light for measurement into a linear capillary through which sample liquid flows is attached to one end of the capillary, and a light leading out member for leading light transmitted through the capillary while transmitting through the sample liquid flowing through the capillary out to the outside is attached to the other end, the light introducing member is a light waveguide inserted into the capillary, and the light leading out member is a window member attached to an opening at the other end of the capillary so the loss of the amount of light transmitted through the capillary can be suppressed, while it is possible for flow cells of which the optical path has a different length to be attached without causing a problem relating to the positional relationships in the optical system, such as an absorbance detector. | 03-06-2014 |
| 20140078500 | PATHOGEN AND PARTICLE DETECTOR SYSTEM AND METHOD - A particle detector has a sample area of cross section no in excess of about 2 mm for containing environmental fluid, a light source on one side of the sample area for directing a collimated or nearly collimated beam of light through the sample air or water so that part of the light beam will be scattered by any particles present in the air or water while the remainder remains unscattered, and a beam diverting device on the possible side of the sample area for diverting or blocking at least the unscattered portion of the beam of light and directing at least part of the scattered light onto a detector. The detector produces output pulses in which each pulse has a height proportional to particle size and a pulse height discriminator obtains the size distribution of airborne particles detected in the air or water sample at a given time from the detector output. The detector may also include a device for discriminating between biological agents and inorganic particles. | 03-20-2014 |
| 20140078501 | ANALYTICAL SYSTEM WITH CAPILLARY TRANSPORT - An analytical system is disclosed. The analytical system includes a storage container configured to store a plurality of capillaries. It also includes a gripper configured to receive at least one of the plurality of capillaries, and move the at least one capillary so that an end of the capillary contacts a sample in a sample container and draws the sample in the capillary. The system also includes a reader configured to detect a signal from the sample in the capillary. | 03-20-2014 |
| 20140104605 | Flow Cell Assembly for Liquid Sample Analyzer - A flow cell assembly for use in a liquid sample analyzer including a radiation source, a sensing device and a liquid sample source to supply a liquid sample includes an entrance joint member, a liquid core waveguide, a liquid sample feed tube, and an input optical fiber. The entrance joint member includes a waveguide receiving bore and a feed tube receiving bore. The liquid core waveguide is mounted in the waveguide receiving bore and defines a waveguide bore. The liquid sample feed tube is mounted in the feed tube receiving bore such that the liquid sample feed tube is in fluid communication with the waveguide bore to fluidly connect the liquid sample source to the waveguide bore. The input optical fiber is mounted in the entrance joint member to transmit radiation from the radiation source to the waveguide bore, which radiation is transmitted through the waveguide bore and the liquid sample therein to the sensing device. | 04-17-2014 |
| 20140111800 | HYBRID, PLANAR OPTOFLUIDIC INTEGRATION - An optofluidic platform is constructed to comprise a vertical integration of optical and fluidic layers. The optical layer enables interaction of light with a fluid for a variety of purposes, including particle detection, manipulation, and analysis. The vertical integration allows layers to be permanently or temporarily attached to each other. Temporary attachments provide the advantage of reusing the same optical layer with different fluidic layers. Most preferably, the optical layer comprises antiresonant reflecting optical waveguide. Further, a fluidic layer can be configured to act as an interface between the optical layer and other fluidic layers attached thereon. Moreover, the fluidic layers can be configured to perform fluidic functions. The optofluidic platform can also comprise a protective layer. As such, a liquid solution can be introduced in the optofluidic platform and single particles contained therein can be optically detected with extremely high sensitivity and without the need for advanced microscopy equipment. | 04-24-2014 |
| 20140132954 | CELL FOR OPTICAL ANALYSIS - The present invention relates to a cell for optical analysis, wherein a flow space of a low depth is formed by attachment, using a simple double-coated tape without out special processing, of a micro flow channel through which a liquid sample passes, thereby enabling: a very easy manufacturing method; a reduction of manufacturing costs, thereby allowing the cell to be more widely used; a maintenance of a short path length of light with respect to the flow space in which the liquid sample flows, thereby enabling accurate optical analysis without diluting a sample with high absorbance; an expansion of a flow space region along the plane vertical to the light-passing direction, thereby enabling smoother optical analysis and improving the accuracy of optical analysis. | 05-15-2014 |
| 20140139832 | ROTATING OPTICS FOR MULTIPLE CUVETTE ARRAY - A system includes a testing instrument to hold a test card having multiple cuvettes radially spaced about a point on the card. A rotatable mount is supported in relation the point on the card when the card is held in the testing system. Optics are supported on the rotatable mount to provide radiation to the multiple cuvettes. | 05-22-2014 |
| 20140146313 | Cuvette for light scattering measurements incorporating evaporation inhibition means - A cuvette for use with light scattering detectors is disclosed. A trough or moat within the cuvette can be filled with solvent which is not in fluid contact with the sample to be measured. This solvent moat creates saturated vapor pressure in the chamber preventing evaporation from the sample when the cuvette is capped. The cuvette itself may be made of an inexpensive polymer which can be polished to high optical quality while still being moldable in complex forms capable of enabling further utility, such as extra griping surfaces, identification tabs allowing the detection instrument to determine the cuvette model, and various sample chamber forms. The novel cuvette may have extremely small sample volumes, while allowing significant overfill of the measurement chamber, improving ease of sample loading. The polymers used may be relatively inexpensive, and therefore the cuvette can generally be discarded after a single use. | 05-29-2014 |
| 20140160474 | OPTICAL REFLECTORS FOR SPECTROMETER GAS CELLS - A spectrometer cell can include a spacer, at least one end cap, and at least one mirror with a reflective surface. The end cap can be positioned proximate to a first contact end of the spacer such that the end cap and spacer at least partially enclose an internal volume of the spectrometer cell. The mirror can be secured in place by a mechanical attachment that includes attachment materials that are chemically inert to at least one reactive gas compound. The mechanical attachment can hold an optical axis of the reflective surface in a fixed orientation relative to other components of the spectrometer cell and or a spectrometer device that comprises the spectrometer cell. The mirror can optionally be constructed of a material such as stainless steel, ceramic, or the like. Related methods, articles of manufacture, systems, and the like are described. | 06-12-2014 |
| 20140176939 | MICROCUVETTE CARTRIDGE - A microcuvette cartridge for optical measurement of a specimen includes: a substrate having a recess on an upper surface thereof to receive a fluid specimen therein, the substrate having a plurality of cavities therein to receive the fluid specimen transported from the recess, the substrate further defining a plurality of channels communicating with the recess and with the plurality of cavities, respectively, to transport the fluid specimen from the recess to the plurality of cavities, said substrate further having one or more of windows at positions corresponding to the plurality of cavities, the windows being transparent to wavelength of light with which the optical measurement is to be carried out so as to allow the light to interact with the fluid specimen in the cavities; and a transport mechanism to promote and complete flows of the fluid specimen from the recess to the plurality of cavities through the plurality of channels. | 06-26-2014 |
| 20140211205 | MICRO-MOLDED CYTOMETER CARTRIDGE WITH INTEGRATED OPTICS - A cytometer cartridge insert includes a micro-molded component and a plastic laminate component. The micro-molded component is embedded in the plastic laminate component. | 07-31-2014 |
| 20140233026 | SHROUDED SENSOR CLIP ASSEMBLY AND BLOOD CHAMBER FOR AN OPTICAL BLOOD MONITORING SYSTEM - An optical blood monitoring system for blocking unwanted light from reaching sensors in a sensor clip assembly fastened to a blood chamber connected in an extracorporeal blood treatment system. The blood chamber has an internal flow cavity for communicating the extracorporeal blood flow and viewing windows to enable the sensor clip assembly to illuminate the blood with light as the blood flows through the blood chamber in order to monitor characteristics of the blood. The sensor clip assembly includes opposing heads with LED emitters and photodetectors. In one embodiment, lenses in the heads are surrounded by shrouds extending from the lenses so that when the sensor clip assembly is fastened to the blood chamber the shrouds block unwanted light from reaching the photodetectors. Either alternatively or as a complement to the shrouds, the blood chamber includes an opaque portion or a portion colored to attenuate particular wavelengths of light to further enhance the overall ability of the blood chamber and sensor clip assembly to block unwanted light from reaching the photodetectors. | 08-21-2014 |
| 20140240701 | Micro Volume Inline Optical Sensor - Micro volume inline optical sensor comprising a flowcell having a sample chamber which has a volume less than 0.4 mL and increases in diameter from two ends toward the middle, a flow passageway intersecting the chamber where the diameter is the greatest, monitoring ports with optically transmissive windows at the ends of the chamber, mounting rings on opposite sides of the flowcell disposed coaxially of an optical axis that passes through the monitoring ports and the sample chamber, and a light source and an optical detector mounted on the mounting rings in alignment with each other along the optical axis. In one embodiment, the sample chamber has a side wall with oppositely inclined frusto-conical sections, and the ends of the chamber are closed and sealed by the monitoring port windows and O-ring gaskets that surround the open ends and are compressed between the body of the flowcell and the windows. | 08-28-2014 |
| 20140247445 | CARTRIDGE FOR CONTAINING A SAMPLE - The present invention relates to a cartridge for containing a sample, for example a sample to be analysed in an analyser such as a spectroscopic analyser. A cartridge for containing a sample to be analysed by an analyser such as a spectroscopic analyser, said cartridge comprising: an upper member including a reservoir; a lower member said upper and lower members being interconnected by a tube for containing the sample, and the lower member including a coupling for connection to a driven rotary means of said analyser whereby the cartridge may be rotated about its axis. | 09-04-2014 |
| 20140247446 | Flow Cell Modules and Liquid Sample Analyzers and Methods Including Same - A flow cell module for use in a liquid sample analyzer includes a module housing, a liquid core waveguide mounted in the module housing to receive a flow of a liquid sample from a liquid sample source, an input optical fiber disposed in the module housing to transmit radiation from a radiation source to the liquid core waveguide, an input termination located on an input end of the input optical fiber, a first kinematic connection mechanism operative to bias the input termination in a first direction along a first axis while permitting displacement of the input termination in a first opposing direction along the first axis, and a second kinematic connection mechanism operative to bias the input termination in a second direction along a second axis while permitting displacement of the input termination in a second opposing direction along the second axis. The second axis is transverse to the first axis. | 09-04-2014 |
| 20140268125 | APPARATUS FOR TAKING AN ACCURATE PHOTOMETRIC MEASUREMENT OF A LIQUID - An apparatus for taking an accurate photometric measurement of a liquid by way of forming a specimen volume of a controlled optical path length for use with photometric measurement equipment is disclosed herein. In some embodiments, the apparatus comprises a transparent body configured for displacing a volume of a fluid and at least one support element wherein the support element is configured to maintain the transparent body at a location such that specimen fluid may enter a void volume to form a specimen volume of a controlled optical path length. In some embodiments, the apparatus comprises a plurality of transparent bodies interconnected by a web such that the transparent bodies are maintained at a spacing arrangement which allows for them to be inserted into the wells of a microplate in order to create a plurality of specimen volumes of a controlled optical path length. | 09-18-2014 |
| 20140268126 | POSITIONING MEANS FOR A MEASURING CELL - The invention relates to a positioning means for a flow cell used for optical detection, comprising a base having at least one contact face, the contact face being provided to make contact with the end of the flow cell, wherein the base has at least one reference face, which is to be aligned and/or positioned relative to the flow channel of a flow cell, and wherein the base is designed to receive a connecting piece in such a way that the latter assumes a predefined attitude and alignment relative to the flow channel. | 09-18-2014 |
| 20140300894 | ANALYZING DEVICE - This invention is to distinguish a position of a measurement cell without using a position sensor that is an electric component, and comprises a cell switching mechanism that switches a measurement position where the measurement cell is located on an optical path and an evacuating position where the measurement cell is evacuated from the optical path so as to make a first moving speed from the measurement position to the evacuating position different from a second moving speed from the evacuating position to the measurement position, and a distinguishing mechanism that detects speed information relating to the first moving speed and the second moving speed by the use of a measurement light and distinguishes the measurement position and the evacuating position. | 10-09-2014 |
| 20140313507 | OPTOFLUIDIC DEVICES AND METHODS FOR SENSING SINGLE PARTICLES - This disclosure provides systems, methods, and apparatus related to optofluidic devices. In one aspect, an optofluidic device includes a substrate, a first nanostructure, a second nanostructure, and a cover. A channel having cross-sectional dimensions of less than about 100 nanometers is defined in a surface of the substrate. The first nanostructure is disposed on the substrate on a first side of the channel and proximate the channel. The second nanostructure is disposed on the substrate on a second side of the channel and proximate the channel. The first and the second nanostructures are disposed on a line that passes across the channel. The cover is disposed on the surface of the substrate. | 10-23-2014 |
| 20140333924 | EPOXY MOLDED GAS CELL FOR OPTICAL MEASUREMENT AND METHOD OF FORMING - The present invention relates to a gas cell ( | 11-13-2014 |
| 20140340674 | Cuvette, Insert, Adapter and Method for Optically Examining Small Amounts of Liquid - Cuvette, comprising at least one measuring area on each one of two arms that are pivotally connected to each other such that from a swung-apart condition, they can be swung together into a measuring position in which the two measuring areas have a distance for positioning a sample between the measuring areas, and means for positioning the two arms in a measuring position in a cuvette shaft of an optical measuring device with a sample between the two measuring areas in a beam path of the optical measuring device that crosses the cuvette shaft. | 11-20-2014 |
| 20150029502 | SPR SENSOR CELL, AND SPR SENSOR - The present invention provides an SPR sensor cell having very excellent detection sensitivity and an SPR sensor. The SPR sensor cell of the present invention includes a detection unit and a sample mounting portion adjacent to the detection unit, wherein the detection unit includes an under-cladding layer, a core layer formed so that at least a part of the core layer is adjacent to the under-cladding layer, a metal layer covering the core layer, and a protective layer formed between the core layer and the metal layer; and the protective layer is formed of a material having a band gap (Eg) of more than 1.0 eV and less than 7.0 eV. | 01-29-2015 |
| 20150103339 | FLOW CELL ASSEMBLY FOR LIQUID SAMPLE ANALYZER - A flow cell assembly for use in a liquid sample analyzer including a radiation source, a sensing device and a liquid sample source to supply a liquid sample includes an entrance joint member, a liquid core waveguide, a liquid sample feed tube, and an input optical fiber. The entrance joint member includes a waveguide receiving bore and a feed tube receiving bore. The liquid core waveguide is mounted in the waveguide receiving bore and defines a waveguide bore. The liquid sample feed tube is mounted in the feed tube receiving bore such that the liquid sample feed tube is in fluid communication with the waveguide bore to fluidly connect the liquid sample source to the waveguide bore. The input optical fiber is mounted in the entrance joint member to transmit radiation from the radiation source to the waveguide bore, which radiation is transmitted through the waveguide bore and the liquid sample therein to the sensing device. | 04-16-2015 |
| 20150109616 | APPARATUS FOR TAKING AN ACCURATE PHOTOMETRIC MEASUREMENT OF A LIQUID - An apparatus for taking an accurate photometric measurement of a liquid by way of forming a specimen volume of a controlled optical path length for use with photometric measurement equipment is disclosed herein. In some embodiments, the apparatus comprises a transparent body configured for displacing a volume of a fluid and at least one support element wherein the support element is configured to maintain the transparent body at a location such that specimen fluid may enter a void volume to form a specimen volume of a controlled optical path length. In some embodiments, the apparatus comprises a plurality of transparent bodies interconnected by a web such that the transparent bodies are maintained at a spacing arrangement which allows for them to be inserted into the wells of a microplate in order to create a plurality of specimen volumes of a controlled optical path length. | 04-23-2015 |
| 20150138542 | MICROCUVETTE - A microcuvette is provided, including a body having a slit inside. The slit connects to an entry slit and an exit slit, and the entry slit and the exit slit are on the opposite side of the body. The microcuvette is characterized in that the slit includes a drainage slit, an optical measuring slit, and a protecting slit. The drainage slit directly connects to the entry slit, the optical measuring slit, and the protecting slit. The protecting slit at least partially surrounds the optical measuring slit and connects to the exit slit. The drainage slit has an average width not larger than the optical measuring slit, and the protecting slit has a width larger than the optical measuring slit. The microcuvette of the present invention is convenient to use, disposable, and can reduce factors affecting measurement results. | 05-21-2015 |
| 20150346081 | Method and Apparatus for Stabilizing the Thickness of an Optical Channel for Extended Pressure Environments - A high pressure optical flow cell system suitable for use in a real time optical particle monitoring system. The system is modular, with at least two housings joined together with removable mechanical attachment devices. Inlet and outlet passageways introduce and remove high pressure fluid into a flow cavity located between adjacent housing faces. An o-ring or other compliant member seal is provided between the faces to prevent leaks of the high pressure fluid. At least one optical window is provided with a substantially planar face flush with the flow cavity surface. An optical assembly maintains the face of the optical window flush with the flow cavity surface over a wide range of temperatures and pressures. A system and method for maintaining the face of the optical window flush with the flow cavity surface over a wide range of temperatures and pressures. | 12-03-2015 |
| 20150377768 | HYBRID, PLANAR OPTOFLUIDIC INTEGRATION - An optofluidic platform is constructed to comprise a vertical integration of optical and fluidic layers. The optical layer enables interaction of light with a fluid for a variety of purposes, including particle detection, manipulation, and analysis. The vertical integration allows layers to be permanently or temporarily attached to each other. Temporary attachments provide the advantage of reusing the same optical layer with different fluidic layers. Most preferably, the optical layer comprises antiresonant reflecting optical waveguide. Further, a fluidic layer can be configured to act as an interface between the optical layer and other fluidic layers attached thereon. Moreover, the fluidic layers can be configured to perform fluidic functions. The optofluidic platform can also comprise a protective layer. As such, a liquid solution can be introduced in the optofluidic platform and single particles contained therein can be optically detected with extremely high sensitivity and without the need for advanced microscopy equipment. | 12-31-2015 |
| 20160011083 | Contact Sensing Probe and Methods of Use for Microplate Liquid Sampling | 01-14-2016 |
| 20160011098 | COMPOUND OPTICAL FLOW CELLS AND METHOD OF MANUFACTURE AND USE | 01-14-2016 |
| 20160077067 | MULTI-MEASUREMENT FLOW CELL ASSEMBLY FOR LIQUID CHROMATOGRAPHY - A detector for detecting constituents of a liquid for use in liquid chromatography is disclosed. The detector includes a first optical flow cell body and a second optical flow cell body, each having a channel therethrough that allows passage of a liquid from an inlet port to an outlet port. The first and second optical flow cell bodies are arranged in series such that the liquid exiting the outlet port of the first optical flow cell body enters the inlet port of the second optical flow cell body. An insulator resides between the first optical flow cell body and the second optical flow cell body, which is adapted to electrically insulate the first optical flow cell body from the second optical flow cell body while allowing the liquid to pass from the first optical flow cell body to the second optical flow cell body. The first optical flow cell body is adapted to facilitate measurement of absorption by the liquid of a first wavelength of light, and second optical flow cell body is adapted to facilitate measurement of absorption by the liquid of a second wavelength of light. The first and second optical flow cell bodies are further adapted to perform as electrodes for measuring the conductivity of the liquid. | 03-17-2016 |
| 20160091435 | METHOD, SAMPLE CARRIER, AND DEVICE FOR THE QUALITATIVE AND/OR QUANTITATIVE DETECTION OF PARTICLES IN A FLUID - The device serves for the qualitative and quantitive detection of particles in a fluid and includes a light source ( | 03-31-2016 |
| 20160103061 | Reaction Vessel, Reaction Vessel Arrangement and Method for Analyzing a Substance - The invention concerns a reaction vessel ( | 04-14-2016 |
| 20160131573 | TESTING EQUIPMENT WITH MAGNIFYING FUNCTION - A testing equipment with a magnifying function includes a carrier, a cover and a magnifying part. The carrier has a specimen holding area formed on the top of the carrier. The cover is stacked on the specimen holding area of the carrier. The magnifying part disposed on the cover. The location of the magnifying part is corresponding to the location of the specimen holding area. The testing equipment of the present application has a simplified and cheap structure for a simple specimen testing. | 05-12-2016 |
| 20160153891 | NEPHELOMETRIC TURBIDIMETER | 06-02-2016 |
| 20160153893 | NEPHELOMETRIC TURBIDIMETER VIAL ARRANGEMENT | 06-02-2016 |
| 20160168398 | STRUCTURE FOR OPTICAL ANALYSIS AND INK COMPOSITION FOR MANUFACTURING THE SAME | 06-16-2016 |
| 20160178529 | SLOT FLOW CELL | 06-23-2016 |
| 20170234789 | LIGHT BLOCKING ASSEMBLY FOR AN ANALYTE DETECTOR | 08-17-2017 |
| 20190145886 | ANALYSIS SYSTEM INCLUDING A CONFINEMENT DEVICE WITH VARIABLE-SIZE MEASUREMENT CHAMBER PARTIALLY DELIMITED BY A FLEXIBLE MEMBRANE | 05-16-2019 |
