| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 356318000 | Monochromatic (e.g., laser) | 82 |
| 20080239311 | FLUORESCENCE DETECTION APPARATUS AND METHOD, AND PRISM USED THEREIN - In order to provide a fluorescence detection apparatus having a high sensitivity, a high processing capacity and a competitive edge in cost, the fluorescence detection apparatus according to this invention irradiate the sample with light so that the aspect ratio of the form of the irradiated region by light on the arrangement surface of the sample may be 1±0.1. The preferable form of irradiate region is not limited to one and varies to some extent depending on the item to be optimized. The form of irradiated region may be, for example, a circle, an equilateral triangle, a square, a regular hexagon and the like. | 10-02-2008 |
| 20080252884 | OPTICAL DETECTION AND ANALYSIS OF PARTICLES - Method and apparatus for the single particle detection of submicron structures such as biological molecules and viruses utilises an optical element ( | 10-16-2008 |
| 20080259330 | LASER-TRIGGERED PLASMA APPARATUS FOR ATOMIC EMISSION SPECTROSCOPY - Multiple energy sources, such as a laser and electrical current, are employed, in close coordination, spatially and temporally, to clean a sample, vaporize its material and excite vapor atoms for the purpose of atomic emission spectroscopy. These methods permit better monitoring and control of the individual processes in real time, lead to higher consistency and higher quality optical emission spectra, and enhance the measurements of non-conducting solids, liquids and gases. Additionally, a portable instrument is provided with both laser source and spectrometer optically coupled to a hand-holdable unit. | 10-23-2008 |
| 20080309934 | SCANNING SPECTROPHOTOMETER FOR HIGH THROUGHPUT FLUORESCENCE DETECTION - A fluorescence spectrophotometer having an excitation double monochromator, a coaxial excitation/emission light transfer module, and an emission double monochromator. Each monochromator includes a pair of holographic concave gratings mounted to precisely select a desired band of wavelengths from incoming broadband light without using other optical elements, such as mirrors. Selected excitation light is directed into a sample well by a light transfer module that includes a coaxial excitation mirror positioned to direct excitation light directly to the bottom of a well of a multi-well plate. Fluorescence emission light that exits the well opening is collected by a relatively large coaxial emission mirror. The collected emission light is wavelength selected by the emission double monochromator. Selected emission light is detected by a photodetector module. | 12-18-2008 |
| 20090009760 | AUTOMATIC ANALYSIS APPARATUS AND AUTOMATIC ANALYSIS METHOD - An automatic analysis apparatus and an automatic analysis method that can perform both spectrophometric measurements for biochemical tests and the turbidimetric immunoassay with high precision by selectively exchanging a white light or at least one monochromatic light based on analysis conditions determined by a measure condition setting unit for respective measuring object. The automatic analysis apparatus includes an irradiating direction setting unit configured to irradiate the selected white light or at least one monochromatic light based on the analysis conditions onto a reaction cuvette along the same light axis and a light detection unit having a plurality of light receiving elements in order to detect the white light of particular determined wavelength lights and the selected monochromatic light. | 01-08-2009 |
| 20090015830 | METHODS AND DEVICES FOR MEASURING A CONCENTRATED LIGHT BEAM - Methods and devices are provided for profiling a beam of light that includes a wavelength λ. The beam of light is received. Secondary light is generated at a wavelength λ′ different from wavelength λ by fluorescing a material with the received beam of light. The secondary light is separated from the received beam of light. The separated secondary light is optically directed to a sensor. | 01-15-2009 |
| 20090021731 | METHOD AND APPARATUS FOR DETECTING EMBEDDED MATERIAL WITHIN AN INTERACTION REGION OF STRUCTURE - A detection system is used during irradiation of an interaction region of a structure with laser light. The structure includes embedded material. The detection system includes means for receiving light emitted from the interaction region. The detection system further includes means for separating the received light into a spectrum of wavelengths. The detection system further includes means for analyzing at least a portion of the spectrum for indications of embedded material within the interaction region. | 01-22-2009 |
| 20090059222 | Integrated nucleic acid analysis - The present disclosure provides fully integrated microfluidic systems to perform nucleic acid analysis. These processes include sample collection, nucleic acid extraction and purification, amplification, sequencing, and separation and detection. The present disclosure also provides optical detection systems and methods for separation and detection of biological molecules. In particular, the various aspects of the invention enable the simultaneous separation and detection of a plurality of biological molecules, typically fluorescent dye-labeled nucleic acids, within one or a plurality of microfluidic chambers or channels. The nucleic acids can be labeled with at least 6 dyes, each having a unique peak emission wavelength. The present systems and methods are particularly useful for DNA fragment sizing applications such as human identification by genetic fingerprinting and DNA sequencing applications such as clinical diagnostics. | 03-05-2009 |
| 20090086205 | METHOD AND APPARATUS FOR IDENTIFYING A SUBSTANCE - A spectroscopic detector includes a tunable light source, such as a continuously tunable, optical parametric oscillator laser; means for measuring the emitted radiation at a plurality of emission wavelengths to obtain a plurality of spectral measurement data; and a processor for processing the spectral measurement data, where the processor includes a multispectral data processing algorithm or is configured for 1) combining the plurality of spectral measurement data into a composite spectrum, and 2) applying the algorithm to the composite spectrum. The spectra such as resonant and near-resonant Raman Spectra that are acquired are more complete and contain more information. A powerful multispectral analysis code such as IHPS, CHOMPS, or ENN analyzes the acquired data points, examining details of the spectra that could not be handled by traditional methods. | 04-02-2009 |
| 20090103084 | OXYGEN SENSOR FOR USE IN HARSH, ESPECIALLY HIGH, pH ENVIRONMENTS - An oxygen sensor usable and accurate in solutions of up to pH 14 is featured. The sensor is fabricated by immobilizing a layer of polystyrene mixed with a fluorophore (e.g., Ruthenium tris(4,7-diphenyl-1,10-phenanthroline) dichloride) in a solvent such as dichloromethane. The mixture may be coated onto a structure such as a stainless steel sensor probe. In typical use, the inventive sensor probe is inserted into a flow cell through which the solution to be monitored flows. A blue LED light source having a wavelength of approximately 470 nm, and a spectrophotometer detector complete the sensor system. In operation, the fluorophore layer of the probe is illuminated by a blue LED light and the fluorescence is reflected back to the spectrophotometer. The monitored solution, typically an electroless gold plating bath, is pumped from the process equipment through the flow cell, and then back to the solution's origin. | 04-23-2009 |
| 20090122311 | Flow Cytometer and Flow Cytometry - In one embodiment of the present invention, a flow cytometer includes a plurality of optical sources, each of which illuminates an excitation beam at a predetermined frequency having a wavelength and a phase different from another; and a guide member for guiding the excitation beams into the same incident optical path to focus onto a dyed particle. According to one aspect of an embodiment of the present invention, it is possible, without requiring introduction of the delay time, to detect a plurality of fluorescence excited at the cell particles labeled with a plurality of fluorescent labeling reagents, by a plurality of laser optical sources. | 05-14-2009 |
| 20090128807 | Photometric instrument - A metallic structure is provided on a surface of a substrate. A component having a longer wavelength than excitation light is detected from luminescence from fixation positions of biomolecules and emitted from a material other than the biomolecules, and is used for photometrical analysis. As the structure, usable is a particulate (a metallic structure of a size not larger than a wavelength of the excitation light), a minute protrusion, or a thin film with minute apertures, which are made of a metal such as gold, chrome, silver or aluminum. In the case of the particulate or the minute protrusion, photoluminescence of the structure is detected with a biomolecule being fixed thereon. In the case of the thin film with minute apertures, Raman scattered light of specimen solution around the biomolecules, and photoluminescence of the metallic structure near the biomolecules are detected with biomolecules being fixed in the apertures. | 05-21-2009 |
| 20090135418 | APPARATUS FOR MEASURING SPATIALLY RESOLVED THE LUMINESCENCE OF SEMICONDUCTOR SAMPLES - An apparatus to measure spatially resolved the luminescence of a semiconductor sample, in particular a semiconductor wafer or any part thereof, includes a rotatable sample holder for the semiconductor sample. This rotatable sample holder is mounted on an xy stage, and a drive mechanism is used to rotate the sample holder rapidly during the measurement. A device excites luminescence light on the semiconductor sample, and an optical device guides a portion of the luminescence light to a detector. The surface of the semiconductor sample is located in the range of a focal point of the optical device. Using a fixation device, it is possible to remove the rotatable sample holder from the xy stage, when required, and to replace it by a cryostat with an optical window and a further semiconductor sample, so that the surface of the further semiconductor sample is essentially located in the focus point of optical device. | 05-28-2009 |
| 20090147255 | METHOD FOR TESTING A SEMICONDUCTOR DEVICE AND A SEMICONDUCTOR DEVICE TESTING SYSTEM - A method for testing a semiconductor device includes irradiating a transistor within the semiconductor device with a light beam, where the irradiating the transistor induces a current within the transistor, and, in response to the irradiating, detecting photon emission from the transistor. A semiconductor device testing system includes a light beam emitter which provides a light beam to a device under test (DUT) to induce a current in the DUT, a filter which receives a photon emission from the DUT and removes from the photon emission a reflected light beam that is reflected from the DUT to provide a filtered photon emission, and a photon detector which detects the filtered photon emission. | 06-11-2009 |
| 20090147256 | Laser scanning microscope - To provide a laser scanning microscope capable of enhancing the degree of freedom of observation while keeping its structure simple. Accordingly, a laser scanning microscope includes a light source, a spectroscopic unit guiding light from the light source to a specimen and guiding the light from the specimen to a detector, light path switching units switching a light path between the spectroscopic unit and the specimen to one among a plurality of light paths with different routes, and a plurality of light deflecting units each disposed in each of the plurality of light paths. | 06-11-2009 |
| 20090180114 | Fine Particle Constituent Measuring Method and Fine-Particle Constituent Measuring Apparatus - Fine particles such as nanoparticles and microparticles is irradiated to generate plasma by focusing an ultrashort pulse laser beam | 07-16-2009 |
| 20090262345 | IMMERSION PROBE FOR LIPS APPARATUSES - The invention relates to an immersion probe ( | 10-22-2009 |
| 20090273782 | LASER ABLATION APPARATUS AND METHOD - Provided is a laser ablation spectroscopy apparatus and method. A pulse laser is focused on the sample site to generate a plasma plume during a laser ablation process. The plasma plume is detected with a spectrometer and an intensified charge coupled device. A sample of material is coupled to a stage movable in the x, y and z directions using an array of x-y-z motors. A change in the height of the sample is detected using a triangulation sensor. The apparatus includes a system computer for synchronizing the movement of the stage in the x, y and z direction during the laser ablation process. The method includes a protocol of generating one or more laser ablations per sample site. The spectral data of the total number of laser ablations for each sample site are averaged together. The protocol includes laser ablating additional sample sites and averaging the spectral data of the total number of sample sites. | 11-05-2009 |
| 20090279086 | Method and apparatus for the high spatial resolution imaging of a structure marked with a substance - For the high spatial resolution imaging of a structure in a sample ( | 11-12-2009 |
| 20090284739 | METHOD AND APPARATUS FOR DETECTING EMBEDDED MATERIAL WITHIN AN INTERACTION REGION OF A STRUCTURE - A system and method processes a structure comprising embedded material. The system includes a laser adapted to generate light and to irradiate an interaction region of the structure. The system further includes an optical system adapted to receive light from the interaction region and to generate a detection signal indicative of the presence of embedded material in the interaction region. The system further includes a controller operatively coupled to the laser and the optical system. The controller is adapted to receive the detection signal and to be responsive to the detection signal by selectively adjusting the laser. | 11-19-2009 |
| 20090290151 | Analysis of arrays by laser induced breakdown spectroscopy - The present invention relates to the detection of materials using laser induced breakdown spectroscopy (LIBS). This invention discloses methods to draw the analyte of interest in a homogeneous matrix and subsequent analysis of these matrices, wherein the said matrices are preferably arranged in an array format. This invention is particularly applicable to analysis of Liquid samples arranged in an array format. | 11-26-2009 |
| 20090290152 | Apparatus and method for measuring concentrations of fuel mixtures using depth-resolved laser-induced fluorescence - The apparatus for measuring concentrations of fuel mixtures using depth-resolved laser-induced fluorescence is a fluorometer equipped with a sample container holder that is movable in the path of the beam from the light source. Fluorescent emissions from the sample mixture pass at 90° to the excitation light path through a slit that is narrow enough that the emission intensity is effectively produced by a thin layer of the sample and focused on a monochromator, with successive thin layers receiving nonuniform excitation radiation due to reduction of intensity along the excitation light source path with increasing depth penetration and due to reabsorption of emitted fluorescence from adjacent layers. The method has a first mode in which the emission spectrum is scanned at a fixed depth, and a second mode in which the sample is moved relative to the emission monochromator slit to vary the depth while keeping the emission wavelength fixed. | 11-26-2009 |
| 20090303474 | METHOD AND MICROSCOPE FOR HIGH SPATIAL RESOLUTION EXAMINATION OF SAMPLES - A method and a microscope, in particular a laser scanning fluorescence microscope, for high spatial resolution examination of samples, the sample ( | 12-10-2009 |
| 20100067003 | TIME-RESOLVED AND WAVELENGTH-RESOLVED SPECTROSCOPY FOR CHARACTERIZING BIOLOGICAL MATERIALS - One embodiment of the present invention provides a system that characterizes a biological sample by analyzing light emissions from the biological sample in response to an excitation. The system first radiates the biological sample with a laser impulse to cause the biological sample to produce a responsive light emission. Next, the system uses a wavelength splitting device to split the responsive light emission into a set of spectral bands of different central wavelengths. The system applies temporal delays to the set of spectral bands so that each spectral band arrives at an optical detector at a different time, thereby allowing the optical detector to temporally resolve the responsive light emission for each spectral band separately. Next, the system captures the delayed spectral bands within a single detection window of the optical detector. The system then processes the captured spectral bands. | 03-18-2010 |
| 20100091278 | WAVELENGTH-MODULATION SPECTROSCOPY METHOD AND APPARATUS - In one embodiment of the spectroscopy method, the method comprises the steps of modulating the wavelength of a monochromatic radiation at a modulation amplitude and a modulation frequency; determining a first variable representative of an absorbance of an analyte in a sample; and demodulating by phase-sensitive detection the first variable at a harmonic of the modulation frequency to produce a harmonic spectrum of the analyte. In one embodiment of the spectroscopy apparatus, the apparatus comprises a laser diode integrated with a first photodetector configured to detect an intensity of a backward emission from the laser diode and act as a reference detector; a second photodetector configured to detect an intensity of laser radiation exiting a sample; and electronic circuitry coupled to the laser diode and the photodetectors, configured to acquire and process spectra of the sample. In another embodiment, the spectroscopy apparatus comprises a beam splitter configured to split the laser radiation into a first radiation portion and a second radiation portion and a first photodetector configured to detect the intensity of the first radiation portion. | 04-15-2010 |
| 20100118301 | SYSTEM FOR ANALYZING A SAMPLE OR A SAMPLE COMPONENT AND METHOD FOR MAKING AND USING SAME - A system and associated method are disclosed for analyzing a sample or sample component including species capable of producing fluorescent light when excited by a light source, where the light source comprises an excimer light source having a high voltage power supply with voltage and current regulation circuitry. | 05-13-2010 |
| 20100165339 | SPATIALLY SELECTIVE FIXED-OPTICS MULTICOLOR FLUORESCENCE DETECTION SYSTEM FOR A MULTICHANNEL MICROFLUIDIC DEVICE, AND METHOD FOR DETECTION - A fixed-optics system for detecting fluorescence light emitted from one or more spatially selected volumes (S), e.g., in one or more microfluidic channels, comprises a detection optical fiber ( | 07-01-2010 |
| 20100238438 | Method and system for stimulated Raman microscopy beyond the diffraction limit - Systems and methods for probing a Raman signature of a sample with a resolution exceeding the diffraction limit are described. These systems, called GASSE (Gain Saturated Stimulated Emission) and iGASSE (interferometric GASSE), are detecting a Raman signal produced in a sample located at the focal spot of a Gaussian pump pulse. Two additional pulsed laser beams (Stokes beams), a central Stokes beam having a Gaussian beam profile and another Stokes beam having an annular beam profile, are also focused to the focal spot. The spatial and temporal phases of the laser pulses are adjusted to produce destructive interference over most of the temporal width of Stokes pulses, which causes emission from the central Stokes beam to narrow well below the diffraction limit. A two-dimensional image of the sample is produced by scanning the combined beams across the sample. The system may find applications in biomedical and semiconductor technology. | 09-23-2010 |
| 20110001966 | REMOTE CHEMICAL AND ELEMENTAL ANALYSIS BY ULTRA FAST SPECTROSCOPY - Systems and methods are provided for monitoring materials using ultra fast laser pulses. Ultra fast laser pulses, such as femtosecond or attosecond laser pulses, are applied to the materials and laser pulses that result from interactions between the ultra fast laser pulses and the materials are collected. Spectral content of the resulting pulses is generated and presented. The elemental composition of the materials is determined using the spectral content. | 01-06-2011 |
| 20110007312 | SYSTEM AND METHOD FOR HIGH PRECISION ISOTOPE RATIO DESTRUCTIVE ANALYSIS - A system and process are disclosed that provide high accuracy and high precision destructive analysis measurements for isotope ratio determination of relative isotope abundance distributions in liquids, solids, and particulate samples. The invention utilizes a collinear probe beam to interrogate a laser ablated plume. This invention provides enhanced single-shot detection sensitivity approaching the femtogram range, and isotope ratios and particle assays that can be determined with relative precision better than about 10%. | 01-13-2011 |
| 20110102788 | Tunable Quantum Cascade Lasers and Photoacoustic Detection of Trace Gases, TNT, TATP and Precursors Acetone and Hydrogen Peroxide - Methods and apparatus for broad tuning of single wavelength quantum cascade lasers and the use of light output from such lasers for highly sensitive detection of trace gases such as nitrogen dioxide, acetylene, and vapors of explosives such as trinitrotoluene (TNT) and triacetone triperoxide (TATP) and TATP's precursors including acetone and hydrogen peroxide. These methods and apparatus are also suitable for high sensitivity, high selectivity detection of other chemical compounds including chemical warfare agents and toxic industrial chemicals. A quantum cascade laser (QCL) system that better achieves single mode, continuous, mode-hop free tuning for use in L-PAS (laser photoacoustic spectroscopy) by independently coordinating gain chip current, diffraction grating angle and external cavity length is described. An all mechanical method that achieves similar performance is also described. Additionally, methods for improving the sensor performance by critical selection of wavelengths are presented. | 05-05-2011 |
| 20110102789 | METHOD AND APPARATUS FOR DETECTING EMBEDDED MATERIAL WITHIN AN INTERACTION REGION OF A STRUCTURE - A detection system is used during irradiation of an interaction region of a structure with laser light. The structure includes embedded material. The detection system includes means for receiving light emitted from the interaction region. The detection system further includes means for separating the received light into a spectrum of wavelengths. The detection system further includes means for analyzing at least a portion of the spectrum for indications of embedded material within the interaction region. | 05-05-2011 |
| 20110116090 | SYSTEM AND METHOD FOR REAL TIME DETERMINATION OF SIZE AND CHEMICAL COMPOSITION OF AEROSOL PARTICLES - This invention is an apparatus and method of real time determination of particle size and optionally chemical composition or both. An aerosol beam generator focuses a beam containing sample particles that passes through a sizing laser beam of approximately constant width to produce light scattering that is detected by a light detection means, allowing generation of electrical pulses that may be used to compute particle velocity. In being formed into a beam, the particles are accelerated to terminal velocities that are functions of their sizes. The duration of time elapsed while a particle passes through the width of the sizing laser beam is a function of its velocity which, in turn, is a function of its size. Chemical composition of the particle is determined by suitable analytical means included in the apparatus, such as mass spectrometry. | 05-19-2011 |
| 20110164248 | SYSTEM AND METHOD FOR HIGH PRECISION ISOTOPE RATIO DESTRUCTIVE ANALYSIS - A system and process are disclosed that provide high accuracy and high precision destructive analysis measurements for isotope ratio determination of relative isotope abundance distributions in liquids, solids, and particulate samples. The invention utilizes a collinear probe beam to interrogate a laser ablated plume. This invention provides enhanced single-shot detection sensitivity approaching the femtogram range, and isotope ratios that can be determined at approximately 1% or better precision and accuracy (relative standard deviation). | 07-07-2011 |
| 20110181879 | Method for Detection of Gases by Laser Spectroscopy, and Gas Sensor - A method and a sensor for detecting a target gas by laser spectroscopy using a laser or a laser diode having a monochrome emission wavelength that can be modulated by varying the operating temperature or the operating current. The wavelength range of the target gas comprises a first modulation of the laser or the laser diode over a first large modulation width, in addition to at least two absorption lines of a reference gas and at least one absorption line of the target gas. The absorption lines are used to calibrate the wavelength scale of the laser or the laser diode in relation to the varied operating temperature or operating current, a second modulation of the laser or the laser diode being performed over a second small modulation width, with the at least one absorption line of the target gas, for detecting the target gas. | 07-28-2011 |
| 20110285994 | LASER SHOCK PEENING MEASUREMENT SYSTEM AND METHOD - A method of monitoring laser shock peening of a material includes forming an ablative layer on the material, directing the laser beam at the ablative layer to produce an acoustic wave in the material, converting the acoustic wave in the material to thermal energy external to the material and measuring the thermal energy. | 11-24-2011 |
| 20120008139 | Laser Assisted Microwave Plasma Spectroscopy - The present invention has a laser and a second energy source act in combination to produce a plasma that emits characteristic radiation for a prolonged period of time. The laser energy is directed to a sample for a period of time to ignite a plasma containing the sample material and to either ablate or vaporize the sample. Energy from a second energy source is supplied to the plasma for a second period of time so that the characteristic radiation emitted by the plasma is maintained. The emitted radiation is used to identify chemical elements contained in the sample. The second period of time is typically larger than the first period of time and may be as long as many milliseconds. | 01-12-2012 |
| 20120033212 | LASER INDUCED BREAKDOWN SPECTROSCOPY INSTRUMENTATION FOR REAL-TIME ELEMENTAL ANALYSIS - A backpack laser-induced breakdown spectroscopy LIBS system to provide rapid in-field elemental analysis of environmental samples important to the safeguarding of special nuclear materials. | 02-09-2012 |
| 20120206722 | High-Resolution Laser Induced Breakdown Spectroscopy Devices and Methods - Provided are laser induced breakdown spectroscopy (LIBS) devices. Embodiments of the devices are configured to obtain a spatial resolution of 10 μm or less. Also provided are methods of using the subject LIBS devices to determine whether one or more elements of interest are present in a target sample. The devices and methods find use in a variety of applications, e.g., submicron and nanoscale chemical analysis applications. | 08-16-2012 |
| 20120262712 | LASER INDUCED BREAKDOWN SPECTROSCOPY - A laser induced breakdown spectroscopy system includes a laser module having a laser source, a sample chamber, a spectrometer arranged to capture spectral data from the sample chamber, a voltage source attached to the sample chamber arranged to apply a voltage to the sample during capture, and a controller in communication with the spectrometer, the voltage source and the laser module to trigger the voltage source and the spectrometer during laser excitation of the sample. A method of operating a laser induced breakdown spectroscopy system includes applying a voltage to a set of electrodes arranged around a sample, striking the sample with a laser during a time interval in which the voltage is being applied to the electrodes, sampling spectral data from the sample after the sample is struck with the laser, and removing the voltage after the spectral data has been sampled. | 10-18-2012 |
| 20120314214 | Laser Induced Breakdown Spectroscopy Having Enhanced Signal-to-Noise Ratio - A material can be analyzed using short pulses by applying a first pulse and a second pulse to the material in which the second pulse is delayed relative to the first pulse. The first and second pulses are directed toward a material along collinear paths, and the material is ablated using the first pulse to cause particles to be emitted from the surface of the material. The emitted particles are atomized and/or ionized using the second pulse, and the radiation from the atomized and/or ionized particles is analyzed. | 12-13-2012 |
| 20130016349 | APPARATUS, SYSTEM, AND METHOD FOR LASER-INDUCED BREAKDOWN SPECTROSCOPYAANM Effenberger, JR.; Andrew J.AACI San DiegoAAST CAAACO USAAGP Effenberger, JR.; Andrew J. San Diego CA USAANM Scott; Jill R.AACI Idaho FallsAAST IDAACO USAAGP Scott; Jill R. Idaho Falls ID USAANM McJunkin; Timothy R.AACI Idaho FallsAAST IDAACO USAAGP McJunkin; Timothy R. Idaho Falls ID US - In laser-induced breakdown spectroscopy (LIBS), an apparatus includes a pulsed laser configured to generate a pulsed laser signal toward a sample, a constructive interference object and an optical element, each located in a path of light from the sample. The constructive interference object is configured to generate constructive interference patterns of the light. The optical element is configured to disperse the light. A LIBS system includes a first and a second optical element, and a data acquisition module. The data acquisition module is configured to determine an isotope measurement based, at least in part, on light received by an image sensor from the first and second optical elements. A method for performing LIBS includes generating a pulsed laser on a sample to generate light from a plasma, generating constructive interference patterns of the light, and dispersing the light into a plurality of wavelengths. | 01-17-2013 |
| 20130070242 | SYSTEM AND ANALYTICAL METHOD FOR LASER-INDUCED BREAKDOWN SPECTROSCOPY - A system for laser-induced breakdown spectroscopy (LIBS) is provided. The system for the LIBS includes a laser module generating a first pulse laser and a second pulse laser. An optical delay device incident by the second pulse laser is used to increase an optical path of the second pulse laser. A Kerr medium incident by the second pulse laser generates a time gate, and allows a plasma light beam generated from a sample incident by the first pulse laser, passing through the time gate and being output at a time point. A detection device receives and measures the plasma light beam output at the time point to generate a signal. A processing module connected to the detection device detects a signal, and compares the signal with a data base to obtain information concerning a composition and element concentrations of the sample. | 03-21-2013 |
| 20130100444 | BULK MATERIAL SAMPLING AND LASER TARGETING SYSTEM - A method is described for providing a continuous flow of a target material past a laser to enable repeated firings of the laser beam at the material in a controlled and uniform fashion. The objective is to provide a means to characterize the target material using laser induced breakdown spectroscopy. The method can be employed in a laboratory or field environment providing improved methods for characterizing in real time the properties of bulk materials. | 04-25-2013 |
| 20130135616 | CABLE IDENTIFICATION USING A UNIQUE CABLE SLEEVE - A cable identification system is provided. The cable identification system includes a cable sleeve with some predetermined unique properties. The cable sleeve is adapted to receive a cable therein. The cable includes one or more electrical conductors therein. The cable identification system further includes a portable measuring device configured to detect the predetermined unique properties of the cable sleeve when positioned adjacent the cable at any point along the cable. | 05-30-2013 |
| 20130155403 | Integrated Nucleic Acid Analysis - The present disclosure provides fully integrated microfluidic systems to perform nucleic acid analysis. These processes include sample collection, nucleic acid extraction and purification, amplification, sequencing, and separation and detection. The present disclosure also provides optical detection systems and methods for separation and detection of biological molecules. In particular, the various aspects of the invention enable the simultaneous separation and detection of a plurality of biological molecules, typically fluorescent dye-labeled nucleic acids, within one or a plurality of microfluidic chambers or channels. The nucleic acids can be labeled with at least 6 dyes, each having a unique peak emission wavelength. The present systems and methods are particularly useful for DNA fragment sizing applications such as human identification by genetic fingerprinting and DNA sequencing applications such as clinical diagnostics. | 06-20-2013 |
| 20130155404 | SYSTEM FOR REAL-TIME ANALYSIS OF MATERIAL DISTRIBUTION IN CIGS THIN FILM USING LASER-INDUCED BREAKDOWN SPECTROSCOPY - The present invention relates to a process control system which can measure the physical properties of a CIGS thin film in real-time in a continuous production line of a CIGS thin film solar cell, more specifically to a system for real-time analysis of material distribution of a CIGS thin film comprising: a header, which comprises a laser irradiation unit producing plasma from the CIGS thin film by irradiating a laser beam to a part of the CIGS thin film; and a spectrum detection optical unit detecting a spectrum generated from the plasma; a transfer unit, which transfers the header at the same rate and to the direction with the transfer rate and direction of the CIGS thin film; and a spectrum analysis unit, which analyzes the spectrum detected by the spectrum detection optical unit. | 06-20-2013 |
| 20130169961 | SYSTEM FOR CLASSIFICATION OF MATERIALS USING LASER INDUCED BREAKDOWN SPECTROSCOPY - A process for real-time classification of materials, the process including: conducting laser induced breakdown spectroscopy on the material (LIBS), wherein at least one second laser pulse is directed to the plume so as to selectively energize only a portion of the plume; measuring optical emissions from the energized portion of the plume; and assessing the elemental composition of the material on the basis of the optical emissions from the excited portion of the plume; wherein the energized portion of the plume is substantially smaller than the entire plume so that the measured optical emissions are relatively independent of the size of the entire plume and hence are relatively independent of the optical absorption and vaporization characteristics of the material, thereby allowing a more accurate assessment of the elemental composition of the material than if the assessment was based on the optical emissions from the entire plume. | 07-04-2013 |
| 20130208275 | ANALYSIS APPARATUS AND ANALYSIS METHOD - The analysis apparatus | 08-15-2013 |
| 20130271761 | LASER INDUCED BREAKDOWN SPECTROSCOPY ANALYSER - A laser induced breakdown spectroscopy (LIBS) analyser ( | 10-17-2013 |
| 20130278930 | Near-Field Material Processing System - Methods and systems for real time feedback and control of near-field material processing are disclosed, including generating electromagnetic radiation from a USP laser coupled to a central processing unit; coupling the electromagnetic radiation to an acousto-optic modulator; coupling the electromagnetic radiation to a beam delivery system; coupling the electromagnetic radiation to a beam delivery fiber; using the electromagnetic radiation to generate a plasma on a target mounted to an adjustable stage coupled to the central processing unit; coupling the electromagnetic radiation from the plasma to a plasma spectrum collection system; coupling the electromagnetic radiation to a spectrum analysis unit; coupling the electromagnetic radiation to a detector; and coupling the detector to the central processing unit; wherein the central processing unit uses the output from the detector as feedback in making adjustments to the USP laser and the adjustable stage. Other embodiments are described and claimed. | 10-24-2013 |
| 20140168645 | QUANTITATIVE ANALYSIS METHOD FOR MEASURING TARGET ELEMENT IN SPECIMEN USING LASER-INDUCED PLASMA SPECTRUM - Disclosed herein is a quantitative analysis method for measuring a target element in a specimen using laser-induced plasma spectrum. More particularly, the present invention relates to a method for analyzing a composition ratio of a target element by calculating peak intensities when peaks overlap each other in a spectrum, and a method for selecting a peak of a wavelength at which the highest precision and reproducibility are secured through linearity of a correlation plot of the peak intensities and a value by dividing a standard deviation value of calibration curve data (peak intensity ratios) by a slope when an internal standard method is used for quantitative analysis of a target element. | 06-19-2014 |
| 20140204375 | MICRO PURGE OF PLASMA REGION - An analysis system includes a laser source generating a laser beam for creating a plasma at a location on a sample. A spectrometer is responsive to photons emitted by the sample at said location and has an output. At least one nozzle is configured to deliver inert gas from a source locally to the location on the sample. A controller is responsive to a trigger signal and is configured to activate the laser source generating a series of laser pulses, open a valve to purge the location locally on the sample, and close the valve after one or more laser pulses. | 07-24-2014 |
| 20140204376 | Automated Multiple Location Sampling Analysis System - An analysis system (e.g., LIBS) includes a laser source generating a laser beam, a movable optic configured to move said laser beam to multiple locations on a sample, and a spectrometer responsive to photons emitted by the sample at those locations and having an output. A controller is responsive to a trigger signal and is configured in a moving spot cycle to adjust the moveable optic, activate the laser source sequentially generating photons at multiple locations on the sample, and process the spectrometer output at each location. | 07-24-2014 |
| 20140204377 | HANDHELD LIBS SPECTROMETER - A handheld LIBS spectrometer includes an optics stage movably mounted to a housing and including a laser focusing lens and a detection lens. One or more motors advance and retract the optics stage, move the optics stage left and right, and/or move the optics stage up and down. A laser source in the housing is oriented to direct a laser beam to the laser focusing lens. A spectrometer subsystem in the housing is configured to receive electromagnetic radiation from the detection lens and to provide an output. A controller subsystem is responsive to the output of the spectrometer subsystem and is configured to control the laser source and motors. In this way, auto-calibration, auto-clean, and auto-focus, and/or moving spot functionality is possible. | 07-24-2014 |
| 20140268134 | LASER SAMPLING METHODS FOR REDUCING THERMAL EFFECTS - A method for reducing thermal effects in laser ablation optical emission spectrometry includes creating discrete ablation spots along an analysis line on a target surface. At least one of the following is also carried out. First, the ablation spots are positioned so that a pair of successive ablation spots are spaced apart from one another along the analysis line and are separated from one another by another ablation spot. Second, when the analysis line comprises generally parallel, adjacent analysis line segments, the ablation spots are positioned so that (A) a pair of successive ablation spots are on different analysis line segments, and (B) the successive ablation spots are positioned to be at different longitudinal positions along the analysis line segments when the different analysis line segments are adjacent to one another. As a result, a linear scan of isolated ablation spots can be generated. | 09-18-2014 |
| 20140327907 | COMPONENT QUANTITATIVE ANALYZING METHOD DEPENDING ON DEPTH OF CIGS FILM USING LASER INDUCED BREAKDOWN SPECTROSCOPY - Disclosed herein is a component quantitative analyzing method depending on a depth of a CIGS film, the method including: generating plasma by irradiating a laser beam on the CIGS film and obtaining spectra generated from the plasma, selecting spectral lines having similar characteristics among spectra of specific elements of the CIGS film, and measuring component composition using a value obtained by summing intensities of the selected spectral lines. | 11-06-2014 |
| 20140340677 | SPECTROSCOPE AND MICROSPECTROSCOPIC SYSTEM - A spectroscope used for a microspectroscopic system includes: a collimating optical system that causes signal light to be substantially collimated light; spectroscopic optical systems and each of which includes at least one of each of spectral elements and in which a wavelength band for spectral separation varies depending on an incident angle of the signal light; at least one of each of optical receivers that detect the signal light spectrally separated by the spectroscopic optical systems; a mechanism that varies the incident angles of the signal light on the spectral elements; and a controller unit that determines the incident angles of the signal light on the spectral elements in accordance with the wavelength band for spectrally separating the signal light and controls the mechanism so as to attain the incident angles. | 11-20-2014 |
| 20140368819 | Methods for Detecting Parasites, Viruses, Bacteria and Drugs in Human and Animal Blood and Cerebral Spinal Fluid, Using Laser-Induced Breakdown Spectroscopy - The present invention relates to methods of detecting parasites, viruses, bacteria and drugs in human and animal blood and cerebral spinal fluid (CSF), using laser-induced breakdown spectroscopy (LIBS). The method includes developing and using algorithmic detection models for detecting compounds, bacteria, viruses and parasites in blood or CSF. The models are developed from a sample of blood or fluid, knowingly having one or more of the compounds or bacteria, viruses, or parasites. Spectra are generated by a LIBS instrument from the sample, and are grouped into either classification spectra or verification spectra. Algorithmic models are developed from the classification spectra; these models are verified with the verification spectra. A second sample of different blood or CSF may then be assessed using the algorithmic models. Spectra generated from this second sample are applied to the models to determine the presence or absence of compounds or bacteria, viruses and parasites of interest. | 12-18-2014 |
| 20150077747 | ACTIVE CHEMICAL SENSING USING OPTICAL MICROCAVITY - A sensor comprises a pair of mirrors ( | 03-19-2015 |
| 20150085281 | ANALYZER AND ANALYSIS METHOD - The objective of the present invention is to reduce the dispersion of a powdered substance, which is the target substance, during the analysis period in an analyzing device that analyzes the target substance by analyzing the light originated from the substance which is in the plasma state. The present invention relates to an analyzing device including a plasma generation means which generates plasma in the space and maintains plasma using the energy of EM radiation emitted from a radiation antenna; and an optical analysis means which analyzes a target substance by analyzing the plasma light generated from target substance of plasma state in the plasma area during the plasma maintenance period where the plasma is maintained by the plasma generation means using the energy of EM radiation. The plasma generation means emits the EM radiation from the radiation antenna in continuous waves during the plasma maintenance period. | 03-26-2015 |
| 20150085282 | LIGHT MEASURING APPARATUS, LIGHT MEASURING METHOD, FILTER MEMBER, AND METHOD OF MAKING FILTER MEMBER - A light measuring arrangement maintains the initial filtering function of an optical filter having a dye dispersed therein. The light measuring arrangement includes a measuring unit configured to measure an intensity of light emitted from a measurement target at a predetermined wavelength. The light measuring arrangement also includes the optical filter unit having the dye. The light measuring arrangement also includes a dye diffusion restricting unit configured to restrict diffusion of the dye from the optical filter unit. The optical filter unit constitutes part of an optical path for the light traveling from the measurement target to the light measuring unit. | 03-26-2015 |
| 20150138544 | MEASUREMENT OF GASEOUS COMPOUND USING SPECTROSCOPY - The method includes guiding a light beam to a first optical path, the light beam being attenuated to an attenuated light beam and detecting a first value indicative of a first intensity of the attenuated light beam. The method further includes generating a last light pulse, dissociating at least part of the gas compound molecules (optionally excited) or dissociated parts thereof (optionally excited) on the first optical path to first part atoms, molecules, ions, or radicals, and to another part using the last light pulse, the light beam being further attenuated by absorption to the first part atoms, molecules, ions, or radicals on the first optical path. The method further includes detecting a second value indicative of a second intensity of the attenuated light beam and determining, using the first and second values, the gas compound content of the gas mixture. A gas compound measuring device measures uses the method. | 05-21-2015 |
| 20150138545 | HANDHELD LIBS ANALYZER END PLATE PURGING STRUCTURE - A handheld LIBS analyzer includes a laser source for generating a laser beam and a spectrometer subsystem for analyzing a plasma generated when the laser beam strikes a sample. A nose section includes an end plate with an aperture for the laser beam, a purge cavity behind the aperture fluidly connected to a source of purge gas, and a shield covering the purge cavity. A vent removes purge gas from the purge cavity when the end plate is placed on the sample. | 05-21-2015 |
| 20150292945 | ANALYSER | 10-15-2015 |
| 20150316413 | AUTOMATED MULTIPLE LOCATION SAMPLING ANALYSIS SYSTEM - An analysis system (e.g., LIBS) includes a laser source generating a laser beam, a movable optic configured to move said laser beam to multiple locations on a sample, and a spectrometer responsive to photons emitted by the sample at those locations and having an output. A controller is responsive to a trigger signal and is configured in a moving spot cycle to adjust the moveable optic, activate the laser source sequentially generating photons at multiple locations on the sample, and process the spectrometer output at each location. | 11-05-2015 |
| 20150346103 | Laser Induced Breakdown Spectroscopy (LIBS) Apparatus and Method for Performing Spectral Imaging of a Sample Surface - This invention discloses a laser induced breakdown spectroscopy (LIBS) apparatus and method for performing spectral imaging of a sample surface. A high repetition rate pulsed laser is employed to produce a train of laser pulses. The laser beam is then scanned by a scanning mechanism over a surface of the subject sample. Each laser pulse produces a LIBS signal from a specific position of the sample surface, which is then measured by a spectrometer device to obtain a LIBS spectrum. The position of the laser beam is recorded and correlated to the corresponding LIBS spectrum. A two dimensional (2-D) mapping of the sample surface to its LIBS spectra is acquired in this manner to construct a LIBS spectral image of the sample surface. | 12-03-2015 |
| 20160054284 | Method And System For Obtaining Geochemistry Information From Pyrolysis Induced By Laser Induced Breakdown Spectroscopy - A method for determining geochemistry of at least one geological sample with laser-induced breakdown spectral measurements performed on the geological sample in a time variant manner with spectral acquisitions made after each of a plurality of measurement shots, spectral pre-processing performed as necessary, and subsequent analysis is applied to the collected data to determine at least one geochemistry parameter of the sample. The method can provide a rapid method to estimate thermal maturity of a sample, which does not require sample preparation, and which can be non-destructive with respect to portions of the sample. A system for performing the method also is provided. | 02-25-2016 |
| 20160061660 | MINIATURE SPECTROMETER AND APPARATUS EMPLOYING SAME - A miniature spectrometer and a miniature spectrometer module employing the same are disclosed. The disclosed miniature spectrometer includes: a band-pass filter which is configured to transmit input light in a surface plasmon mode and which has an array of waveguides which are configured to output a plurality of different transmission wavelength bands; an in-coupler configured to couple the transmitted input light to a first end of the array of waveguides; and an array of optical detectors configured to detect respective lights which are output from a second end of the array of waveguides. | 03-03-2016 |
| 20160069745 | Laser Induced Breakdown Spectroscopy (LIBS) Apparatus Based on High Repetition Rate Pulsed Laser - This invention discloses a laser induced breakdown spectroscopy (LIBS) apparatus based on a high repetition rate pulsed laser. The laser produces a train of laser pulses at a high repetition rate in the kHz or even higher range. When the laser beam hits the sample, it generates several thousands of micro-plasmas per second. Synchronized miniature CCD array optical spectrometer modules collect the LIBS signal from these micro-plasmas. By adjusting the integration time of the spectrometer to cover a plurality of periods of the laser pulse train, the spectrometer integrates the LIBS signal produced by this plurality of laser pulses. Hence the intensity of the obtained LIBS spectrum can be greatly improved to increase the signal-to-noise ratio (SNR) and lower the limit of detection (LOD). In addition, the influence of pulse to pulse variation of the laser is minimized since the obtained LIBS spectrum is the spectrum of a plurality of micro-plasmas produced by a plurality of laser pulses. The high repetition rate laser also makes it possible for fast scanning the laser beam over the sample surface such that an average spectrum of the sample is collected to overcome the sample non-uniformity issue or for performing spectral imaging of the sample by correlating the obtained LIBS spectrum with the position of the scanning laser beam. | 03-10-2016 |
| 20160084709 | HANDHELD LIBS SPECTROMETER - A handheld LIBS spectrometer system features an optics stage moveable with respect to a housing and including a laser focusing lens. A laser source is mounted in the housing for directing a laser beam to a sample via the laser focusing lens. A detection fiber is mounted in the housing and is fixed relative thereto. A first mirror is fixed relative to the housing and includes an aperture for the laser beam. This mirror is oriented to re-direct plasma radiation for delivery to the detection fiber. A controller subsystem is responsive to the output of a spectrometer subsystem and is configured to control the laser source and the optics stage. | 03-24-2016 |
| 20160091434 | Method for Elemental Analysis of a Snack Food Product in a Dynamic Production Line - A method and apparatus for analyzing one or more elements of targeted moving snack food surfaces uses laser-induced breakdown spectroscopy to detect the presence, absence, or amount of an element on a heterogeneous surface, including seasoned and ready-to-eat snack foods. A laser is used to quantify the element concentration without destroying the targeted sample. An automated on-line system may be integrated into the method to create a closed-loop feedback control system, adjusting the concentration as desired. | 03-31-2016 |
| 20160109349 | PORTABLE PARTICLE SPECTOMETER - Methods and systems for characterizing particles in an aerosol are disclosed. A system includes a collection container that utilizes the principles of elutriation to collect particles of selected aerodynamic diameter ranges within a measurement region. A particle detector is used to detect and characterize particles that have settled into the measurement region. | 04-21-2016 |
| 20160116415 | METHOD OF LASER-INDUCED BREAKDOWN SPECTROSCOPY IN AIR - A method for detecting an element in a sample using molecular emission by double pulse laser-induced breakdown spectroscopy is provided. The method includes observing emissions from molecules including the element to be detected. The method is particularly useful for detecting halogens, whose elemental emissions are difficult to detect, rare earth elements and boron. | 04-28-2016 |
| 20160116416 | Substrate Enhanced Laser-Induced Breakdown Spectroscopy (LIBS) Apparatus - This invention discloses a substrate enhanced laser-induced breakdown spectroscopy (LIBS) apparatus for liquid analysis. The LIBS apparatus comprises a pulsed laser for producing a laser beam, a substrate made of a material having a high absorption coefficient at the laser wavelength for receiving the liquid sample, an optical lens or mirror for focusing the laser beam onto the liquid sample to produce a plasma emission, and a spectrometer for measuring the optical spectrum of the plasma emission. When the thickness of the liquid sample reaches an optimum value, the plasma emission from the liquid sample is enhanced by the substrate to produce a strong LIBS signal for spectral analysis. | 04-28-2016 |
| 20160131581 | IN-SITU ON-LINE DETECTION DEVICE AND METHOD FOR LONG-DISTANCE METALLURGICAL LIQUID METAL COMPONENT - An in-situ on-line detection device and detection method for a long-distance metallurgical liquid metal component. The detection device comprises a front-end high-temperature resistant probe ( | 05-12-2016 |
| 20160139053 | AUTOMATED FOCUSING, CLEANING, AND MULTIPLE LOCATION SAMPLING SPECTROMETER SYSTEM - An analysis system includes a moveable focusing lens, a laser (typically an eye safe laser) having an output directed at the focusing lens, and a spectrometer outputting intensity data from a sample. A controller system is responsive to the spectrometer and is configured to energize the laser, process the output of the spectrometer, and adjust the position of the focusing lens relative to the sample until the spectrometer output indicates a maximum or near maximum intensity resulting from a laser output focused to a spot on the sample. | 05-19-2016 |
| 20160187201 | LASER INDUCED BREAKDOWN SPECTROSCOPY SAMPLE CHAMBER - Methods and apparatus for laser induced breakdown spectroscopy (LIBS) sample chamber. An apparatus includes a sample chamber, a laser source connected to an excitation optics assembly, the excitation optics assembly connected to a first port on the sample chamber, a collimator assembly connected to a spectrometer, the collimator assembly connected to a second port on the sample chamber, and a first lens tube positioned on the first port and a second lens tube positioned on the second port, the first lens tube protecting the first port connected to the excitation optics assembly and the second lens tube protecting the second port connected to the collimator assembly from particles emitted when a laser pulse from the laser source ablates a surface of a target sample and generates a plasma. | 06-30-2016 |
| 20160187260 | LIBS MEASUREMENT TUBE - (EN) The invention relates to a special LIBS measurement tube focusing unit, referred to simply as LIBS measurement tube, for vertically dipping into a material to be analyzed, which material is moved in a horizontal flow, characterized in that the measurement tube extends vertically and is internally hollow and open at least at the bottom end, such that a bottom edge is formed at the bottom end, the measurement tube has an inlet for coupling in a laser beam and an outlet for coupling out an emission spectrum at the upper end, the measurement tube is constructed in such a way that, in the measurement tube, the laser beam is focused at the material to be analyzed, specifically bulk material, in particular raw, intermediate, and end products from the processing of potash, magnesium, rock salt, or evaporated salt, but without additional scattering and deflection occurring, such that a plasma of the material to be analyzed is produced within the measurement tube by the laser radiation and the emission spectrum of the material to be analyzed reaches the outlet for outcoupling through the interior of the measurement tube, and scrapers ( | 06-30-2016 |
| 20160252397 | LIBS ANALYZER SAMPLE PRESENCE DETECTION SYSTEM AND METHOD | 09-01-2016 |
| 20160252398 | LIBS ANALYZER SAMPLE PRESENCE DETECTION SYSTEM AND METHOD | 09-01-2016 |
| 20180024106 | FACILITY AND METHOD FOR MONITORING THE VARIATION IN THE QUALITY OF A LUBRICANT | 01-25-2018 |
