Class / Patent application number | Description | Number of patent applications / Date published |
356036000 | WITH SAMPLE PREPARATION | 73 |
20080198358 | FIBER OPTIC DEVICE FOR SENSING ANALYTES - A device for sensing analyte concentration, and in particular glucose concentration, in vivo or in vitro is disclosed. An optical conduit, preferably an optical fiber has an optical system at the proximal end of the optical conduit. A sensing element is attached to the distal end of the optical conduit, and comprises at least one binding protein adapted to bind with at least one target analyte. The sensing element further comprises at least one reporter group that undergoes a luminescence change with changing analyte concentrations. Optionally, the sensing element includes reference groups with luminescence properties that are substantially unchanged by variations in the analyte concentrations. | 08-21-2008 |
20080198359 | DIRECT ICP EMISSION SPECTRAL ANALYSIS METHOD OF SOLID SAMPLE - An ICP analysis method for solid samples which can secure reliability of the analytical results. The present invention provides an analytical method in which a finely powdered solid sample is directly injected into an inductively coupled plasma-aided emission spectrometer, wherein standard liquid samples of known concentration of objective element are analyzed by the spectrometer to establish a calibration curve for the element; at least one standard sample of finely powdered solid of known concentration is analyzed by the spectrometer to determine a conversion factor by a given procedure; and the result of the finely powdered solid sample is corrected using the conversion factor. | 08-21-2008 |
20080204708 | Functionalised Surface Sensing Apparatus and Methods - We describe an evanescent wave cavity-based optical sensor. The sensor comprises an optical cavity formed by a pair of highly reflective surfaces and including a totally internally reflecting (TIR) surface generating an evanescent wave to provide a sensing function. The TIR surface is provided with a functionalising material over at least part of said TIR surface such that said evanescent wave interacts with said material, and whereby an interaction between said functionalising material and a target to be sensed is detectable as a change in absorption of said evanescent wave. The technique is extremely sensitive and thus in a gas sensor the evanescent wave TIR surface is provided with a solvating medium, and in other configurations a partition or atrium is provided for the evanescent wave sensing region. | 08-28-2008 |
20080204709 | BIOSENSOR USING MICRODISK LASER - A compact sensor for detecting the presence of biological or chemical species includes a microdisk laser and a wavelength shift detector. The microdisk laser is coated with a biological or chemical recognition element, which binds preferentially with a target analyte. Because the recognition element and the target analyte adhere to the sidewall surface of the microdisk laser, they increase the effective diameter of the laser, which shifts the output wavelength by a detectable amount. The presence of a wavelength shift indicates the presence of the target analyte, and the magnitude of the wavelength shift corresponds to the mass load of the target analyte on the sidewall surface of the microdisk laser. | 08-28-2008 |
20080212068 | Porous Photonic Crystal with Light Scattering Domains and Methods of Synthesis and Use Thereof - The invention includes sensors and sensing methods for determining cell morphology and/or chemical composition of an analyte. A porous substrate exhibiting a first optical signal is exposed to a target analyte and subsequently monitored for changes in the optical signal. More specifically, a photonic or porous substrate having a well-defined and highly tunable reflectivity or transmission spectrum, such as porous silicon (Si), porous alumina, porous Ge, porous GaAs, porous SiO2 and porous polymer, is used for example. A porous or photonic substrate is exposed to an analyte, such as a cell or other macromolecule, and changes in the scattered light are observed over time to determine cell morphology and/or chemical composition of the analyte using the substrate. | 09-04-2008 |
20080212069 | Method, system, and compositions for cell counting and analysis - The present invention provides a low cost imaged-based system for detecting, measuring and/or counting labeled features of biological samples, particularly blood specimens. In one aspect, the invention includes a system for imaging multiple features of a specimen that includes one or more light sources capable of successively generating illumination beams each having a distinct wavelength band and a plurality of differentially excitable labels capable of labeling a specimen comprising multiple features, such that each different feature is labeled with a different differentially excitable label. System of the invention may further include a controller operationally associated with the one or more light sources for successively directing illumination beams onto the specimen so that each of the different differentially excitable labels is successively caused to emit an optical signal within the same wavelength band, an optical system capable of collecting such emitted optical signals and forming successive images corresponding to the labeled features of the specimen on a light-responsive surface to form successive sets of image data thereof, and a disposable cuvette for collection and optical analysis of non-red blood cells. | 09-04-2008 |
20080212070 | KIT AND METHOD FOR MULTI-ANALYTE DETERMINATION - The invention is related to different embodiments of a kit for the simultaneous qualitative and/or quantitative determination of a multitude of analytes comprising
| 09-04-2008 |
20080218731 | Diagnostic test device - A diagnostic test device comprises means for sampling a liquid biological sample. Means is provided for reacting the sample with a reagent to provide one or more visible indicia. A photodetector for scans a detection region to produce a pulsed output indicative of the presence of the one or more indicia. The photodetector is connected to a signal processing circuit for processing the pulsed output. The signal processing circuit produces an output change in response to light intensity variation which is substantially independent of baseline current. | 09-11-2008 |
20080225268 | Electric-field-enhancement structures including dielectric particles, apparatus including same, and methods of use - In one aspect of the present invention, an electric-field-enhancement structure is disclosed. The electric-field-enhancement structure includes a substrate and an ordered arrangement of dielectric particles having at least two adjacent dielectric particles spaced from each other a controlled distance. The controlled distance is selected so that when a resonance mode is excited in each of the at least two adjacent dielectric particles responsive to excitation electromagnetic radiation, each of the resonance modes interacts with each other to result in an enhanced electric field between the at least two adjacent dielectric particles. Other aspects of the present invention are electric-field-enhancement apparatuses that utilize the described electric-field-enhancement structures, and methods of enhancing an electric field between adjacent dielectric particles. | 09-18-2008 |
20080231834 | SURFACE PLASMON ASSISTED MICROSCOPE - The present invention includes a microscope and a method for using the microscope for single molecule with reduced photobleaching of a fluorophore ( | 09-25-2008 |
20080239283 | Particle measuring method and particle measuring apparatus - The present invention relates to a particle measuring method for irradiating light to a surface of a substrate to scatter the light so as to measure a condition of particles on the substrate based on the scattered light. The particle measuring method according to the present invention comprises the steps of: heating a certain liquid to obtain a steam; supplying the steam onto a substrate so that a content of the steam is absorbed by each particle, while a temperature of the substrate is maintained in such a manner that the steam does not condense on the substrate; cooling the substrate before the particle dries so that the content absorbed by the particle is solidified, while preventing generation of solidified substance on regions of the surface of the substrate to which no particle adheres; and irradiating light to the substrate to scatter the light and detecting the scattered light, under a condition in which the content absorbed by the particle has been solidified. | 10-02-2008 |
20080246946 | METHOD AND A SYSTEM FOR DETERMINATION OF PARTICLES IN A LIQUID SAMPLE - The present invention relates to a method for the assessment of quantity and quality parameters of biological particles in a liquid analyte material. The method comprises applying a volume of a liquid sample to an exposing domain from which exposing domain electromagnetic signals from the sample in the domain can pass to the exterior, and exposing, onto an array of active detection elements such as CCD-elements, a spatial representation of electromagnetic signals having passed from the domain, the representation being detectable as an intensity by individual active detection elements, under conditions permitting processing of the intensities detected by the array of detection elements during the exposure in such a manner that representations of electromagnetic signals from the biological particles are identified as distinct from representations of electromagnetic signals from background signals. The size of the volume of the liquid sample is sufficiently large to permit the assessment of the quantity and quality parameters to fulfill a predetermined requirement to the statistical quality of the assessment based on substantially one exposure. | 10-09-2008 |
20080278706 | METHOD FOR PRE-TREATING SPECIMEN AND METHOD FOR ANALYZING SPECIMEN - A pre-treatment method for analyzing a specified portion in a specimen composed of a biological tissue includes the steps of preparing a specimen to be analyzed, determining a specified portion in the specimen; and applying an analysis inhibitor to a portion except the specified portion of the specimen using a droplet spray method. | 11-13-2008 |
20080291424 | HYDROGEL-ACTUATED MICROMIRRORS FOR OPTICAL SENSING - A thin, deformable member may be fixed at one end, while another portion of the member rests on a hydrogel substance whose thickness changes depending on a characteristic of a liquid that permeates the hydrogel. When the hydrogel changes thickness and causes part of the member to tilt, a reflective surface on the member may reflect light in a different direction. Appropriate sensors may detect the change in the direction of the reflected light, allowing determination of the change in thickness, which in turn permits determination of the relevant characteristic of the liquid. | 11-27-2008 |
20080316465 | SAMPLE HOLDER AND SAMPLE PREPARATION DEVICE - An apparatus for forming a solid sample from a sample solution and then analyzing the solid sample to determine the solid form of the sample is provided. The apparatus may optionally comprise a masking block with an array of openings, a film on which the solid sample can be deposited, and a sheet. The apparatus may optionally comprise a masking block with an array of openings and a sheet on which the sample can be deposited. The apparatus may comprise the formation unit of a system for forming a solid sample and analyzing the solid sample. The system may further comprise an analysis unit comprising the film and/or sheet with the solid samples and a spacer unit attached to the film after it has been removed from the formation unit. Methods for using the apparatus and/or system of the present invention are also provided. | 12-25-2008 |
20090002682 | Laser Microdissection Method, Control System for a Laser Microdissection Device and Carrier Device - A microdissection method for separating and taking a target zone of a biological preparation, disposed on a carrier device with a laser light-absorbent incisable layer and a carrier means, comprises cutting the preparation and the incisable layer along an edge segment of the target zone and removing of a non-excised segment of the incisable layer from the carrier means. | 01-01-2009 |
20090027653 | METHOD AND SYSTEM FOR IMMERSION BASED INSPECTION - A method for immersion based inspection, the method includes: (i) receiving an article that comprises a wafer and a transparent element, wherein a first fluid substantially fills a space between an upper surface of the wafer and the transparent element; and (ii) inspecting the wafer by utilizing a lens that contacts a second fluid element that also contacts the transparent element. | 01-29-2009 |
20090027654 | Analyzer - The concentration of impurities contained in ultrapure water or press water can be efficiently analyzed with high precision. | 01-29-2009 |
20090040505 | In-Stream Spectroscopic Elemental Analysis of Particles Being Conducted Within a Gaseous Stream - A particle presentation apparatus for presenting particles being conducted within a gaseous stream for in-stream spectroscopic elemental analysis includes a particle blending section for homogenizing the distribution particles of significantly different sizes received within a gaseous stream of randomly distributed particles; and a particle sampling section including a window that is adapted for passing a particle excitation beam, such as a laser beam, and photon emissions, and a conduit for conducting the homogenized stream of particles past the window so that a particle excitation beam passing through the window can pass into the stream of homogenized particles. The apparatus may be used in combination with a drilling machine, wherein the particle blending section is coupled to an outlet pipe of the drilling machine for receiving a said gaseous stream of randomly distributed particles that are expelled from a drill hole. | 02-12-2009 |
20090091740 | METHODS AND SYSTEMS FOR ANALYZING SOLIDS - Methods and systems for the analysis of solid materials are disclosed. The present invention comprises x-ray and Raman analytical techniques and systems which facilitate the rapid characterization of a plurality of solid samples. | 04-09-2009 |
20090153836 | Enumeration of Thrombocytes - A sample acquiring device for volumetric enumeration of thrombocytes in a blood sample is provided which comprises a measurement cavity for receiving a blood sample. The measurement cavity has a predetermined fixed thickness. The sample acquiring device further comprises a reagent, which is arranged in a dried form on a surface defining the measurement cavity. The reagent comprises a haemolysing agent for lysing red blood cells in the blood sample, and optionally a staining agent for selectively staining thrombocytes in the blood sample. A system comprises the sample acquiring device and a measurement apparatus. The measurement apparatus comprises a sample acquiring device holder, a light source, and an imaging system for acquiring a digital image of a magnification of the sample. The measurement apparatus further comprises an image analyser arranged to analyse the acquired digital image for determining the number of thrombocytes in the blood sample. | 06-18-2009 |
20090251681 | SYSTEM AND METHOD FOR LIQUID DELIVERY EVALUATION USING SOLUTIONS WITH MULTIPLE LIGHT ABSORBANCE SPECTRAL FEATURES - A system and related method for improved liquid delivery evaluation using a solution containing one or more dyes such that the solution exhibits multiple distinct detectable light absorbance spectral features for calibrating or testing over extended volume or dilution ranges are described. The system includes: a photometric instrument capable of measuring optical absorbance at multiple wavelengths; one or more sample solutions to be dispensed using the liquid delivery system whose performance is being tested or calibrated; and vessels optionally pre-filled, or filled by the user, with diluent solution. The sample solutions contain one or more dyes, chosen so that multiple distinct detectable light absorbance spectral features, such as peaks and/or valleys and/or plateaus of the solution can be distinguished for volume or dilution ranges of interest. The concentrations of the dyes may be chosen so that a large volume delivery device is calibrated using a spectral feature in the solution with a low absorbance per unit pathlength, while a small volume delivery device is calibrated with the same sample solution but using a different spectral feature with a high absorbance per unit pathlength. | 10-08-2009 |
20090251682 | BIOSENSOR - A biosensor includes an external cavity laser device having an optical resonator with at least one total-reflection mirror and a semi-reflection mirror corresponding to the total-reflection mirror, wherein the total-reflection mirror includes a transparent substrate and a surface plasma resonance unit disposed on the transparent substrate. The total-reflection mirror includes a transparent substrate, and the surface plasma resonance unit is disposed on the transparent substrate. | 10-08-2009 |
20090303461 | DETECTION OF ENHANCED MULTIPLEX SIGNALS BY SURFACE ENHANCED RAMAN SPECTROSCOPY (SERS) - Various methods of using Raman-active or SERS-active probe constructs to detect analytes in biological samples, such as the nucleic acid and/or protein-containing analytes in a body fluid are provided. | 12-10-2009 |
20100014067 | DETECTION OF AIRBORNE PARTICULATES - The present disclosure provides method and apparatus for detection of airborne particulates. Liquid droplets comprising reagents capable of reacting with particulates whereby to produce emitted light are introduced to an air flow comprising particulates, whereupon the particulates and liquid droplets agglomerate thereby producing the emitted light. The light is detected by a suitable detector ( | 01-21-2010 |
20100073665 | DEFECT DETECTION USING TIME DELAY LOCK-IN THERMOGRAPHY (LIT) AND DARK FIELD LIT - To increase inspection throughput, the field of view (FOV) of an IR camera can be moved over the sample at a constant velocity. Throughout this moving, a modulation (e.g. optical or electrical) can be provided to the sample and IR images can be captured using the IR camera. Moving the FOV, providing the modulation, and capturing the IR images can be synchronized. The IR images can be filtered to generate the time delay LIT, thereby providing defect identification. In one embodiment, this filtering accounts for the number of pixels of the IR camera in a scanning direction. For the case of optical modulation, a dark field region can be provided for the FOV throughout the moving, thereby providing an improved signal-to-noise ratio (SNR) during filtering. | 03-25-2010 |
20100157284 | Laser capture microdissection system and electric moving stage thereof - A laser capture microdissection system includes a laser illuminator, a fiber and an electric moving stage. The fiber has a probe terminal and a coupling terminal for being coupled to the laser illuminator. The electric moving stage includes a fiber probe holder, a driving mechanism for vertical shift, a stage unit, a driving mechanism for horizontal shift and an electronic control unit. The driving mechanism for vertical shift serves for driving the fiber probe holder to shift in microscale. The stage unit has a nanoscale shift controller, a placing portion, wherein the nano-scale shift controller is connected to the placing portion, and the placing portion is located under the fiber probe holder. The driving mechanism for horizontal shift serves for driving the stage unit to shift in microscale. The electronic control unit is electrically connected to the nanoscale shift controller and the driving mechanism for horizontal shift. | 06-24-2010 |
20110069300 | Method and Apparatus for Single-Axis Cross-Sectional Scanning of Parts - Improved methods and apparatus for cross-sectional scanning of parts employ a scanning station in which the focal plane of the scanning apparatus never moves in the vertical direction, i.e., the direction in which the stage of the part/potting combination moves. Distinct steps of material removal and scanning alternate with an intermediate step of moving the part/potting combination in the vertical direction after a surface layer has been removed, thus placing the newly-created surface back into the non-moving focal plane for the next scanning step. A removal station (not the stage carrying the part/potting combination) repeatedly moves into and out of the field of view of the scanning station between scanning steps. The material removal station is specially configured to remove the desired surface layer of the part/potting combination and the created debris, without requiring the separate environment characteristic of previous commercial applications. | 03-24-2011 |
20110157580 | PRETREATMENT APPARATUS AND MASS SPECTROMETER EQUIPPED WITH THE SAME APPARATUS - To perform accurate measurement in the analysis of chemical components with low concentration, pretreatment such as concentration and purification of samples is essential. For high-throughput of pretreatment of biological samples, various random clinical testing is encountered, where analytes change from sample to sample. The pretreatment apparatus has a separating agent selectively separating a specific component by allowing a sample solution to flow therethrough. A holding section holds a plurality of housing sections, which house the separating agent therein, and has an endless track. A pressurizing section applies pressure to the housing section in a continuous and random-accessible manner; and an extraction solution receiver mechanism selectively receives an extracted solution from the separating agent housed in the housing section. A mass spectrometer is connected to the pretreatment apparatus. Thus, a large number of specimens can be simultaneously processed. | 06-30-2011 |
20110181866 | METHOD AND APPARATUS FOR CUTTING AND COLLECTING DISSECTED SPECIMENS - Methods and devices for cutting and collecting dissected specimens are described herein. In one embodiment, the method for dissecting and collecting specimens includes the following steps: placing a sample onto a slide of a laser dissection microscope, the slide being translatable in its plane of extension, lowering an adherent collection device centered on the optical axis onto the probe, wherein the adherent collection device, in its lowered state, adheres to the sample, is freely translatable with the slide and decoupled from the optical axis of the microscope, and, in its raised state, is fixed relative to the optical axis, dissecting one or more specimens from the sample, wherein the following steps are performed if the next specimen to be dissected is located outside of a predetermined collection radius of the adherent collection device: raising the adherent collection device, translating the slide to a given position relative to the optical axis of the microscope in order to decenter the center of the specimen to be dissected from the optical axis of the microscope, lowering the adherent collection device onto the sample, and dissecting one or more subsequent specimens, wherein, after each step of raising the adherent collection device, the predetermined position is spaced apart from all previously determined positions by at least one predetermined distance. | 07-28-2011 |
20110228256 | OPTICAL DETECTION PROCESS FOR DETECTING MICRON-SIZED OBJECTS IN SOLUTION - An optical detection process relates to detecting micron- or submicron-sized particles or organisms by means of a contact imaging device, the particles or organisms being immersed in a liquid droplet and the detection being carried out by means of a matrix of photosensitive cells or photosites. The process includes one detection step or a succession of detection steps carried out while the liquid droplet is evaporating. The process may also include a detection step carried out after the liquid droplet has evaporated. The process allows a three-dimensional distribution of the particles or organisms in the initial unevaporated droplet to be reconstructed. | 09-22-2011 |
20120320365 | SAMPLE PREPARATION FOR SPECTROSCOPY ANALYSIS - A sample is cleaned up for spectroscopic analysis by receiving a slide substrate having the sample thereon, fixing the sample to a substrate surface of the slide substrate by applying heat to the slide substrate for a predetermined heating time and incubating the sample on the slide substrate for a predetermined incubation time after fixing the sample to the slide substrate. The sample is further cleaned by washing the sample on the slide substrate after the sample has been incubated and drying the sample by applying heat to the slide substrate for a predetermined drying time, wherein the sample on the slide substrate after drying has retained particles of interest and interferant particles are removed from the substrate. A substrate is also provided for sample collection, which is culturable and Raman silent. | 12-20-2012 |
20130100433 | Aperture System for Multi-Angle Light Scattering Detectors - An apparatus for measuring the light scattering properties of a sample in a liquid medium, wherein the liquid medium with the sample is illuminated by a laser beam in a measuring cell transversely to the direction of filling the liquid medium in the measuring cell or transversely to the flow direction of the liquid medium within the measuring cell, comprising a laser, a cylindrical measuring cell, a first inner aperture system, a second outer aperture system and at least two detectors, wherein the detectors are arranged outside of the second outer aperture system so that they collect the light scattered on the sample within set, different angle ranges, wherein the first inner aperture system and the second outer aperture system are formed and arranged circularly and concentrically around the axis of the measuring cell. Use of the apparatus and a method that makes use of the apparatus are also disclosed. | 04-25-2013 |
20130107244 | GAS PHASE COOLING AND MIXTURE ANALYSIS | 05-02-2013 |
20130128260 | System and Method for Detection of Analytes in Exhaled Breath - A device, system, and methods are disclosed for detecting the presence or determining a quantitative amount of at least one drug substance from exhaled breath of a subject in-situ. A collecting surface has a Surface Enhanced Raman Spectroscopy (SERS)-active layer that comprises at least one SERS-active material. The collecting surface is arranged as an outer surface of a waveguide for contact with exhaled breath, such that at least traces of said at least one drug substance in said exhaled breath can contact said SERS-active layer for read-out of a Raman shift spectrum that is detected in-situ for said detecting the presence or determining the quantitative amount of said at least one drug substance from said exhaled breath. | 05-23-2013 |
20130141713 | Process For Predicting Metallic Gloss Of Coating Resulting From Coating Compositions By Wet Color Measurement - The present invention is directed to a process for controlling the metallic gloss of a coating resulting from a coating composition, such as automotive OEM or refinish paint, that contains flakes, such as metallic aluminum flakes. Thus, by adjusting the amount of flattener added to the coating composition, the gloss of a coating resulting therefrom can be controlled from glossy to flat (matte) finish. The process includes measuring reflectance (L-value) of a layer of the coating composition applied over a test substrate by using gloss prediction device of the present invention. The metallic gloss of a coating resulting from the layer is then measured. The process is repeated with varying amounts of one or more flatteners added to the composition and the metallic gloss vs. reflectance is plotted on a graph. Then by means of a curve fitting equation, a metallic gloss prediction curve is plotted. By measuring the reflectance of a wet layer of a target coating composition, the metallic gloss that would be produced by a coating from that target coating composition can then be predicted by using the gloss prediction curve. The process is most useful during the manufacture of coating compositions, such as automotive OEM and refinishes paints. | 06-06-2013 |
20130162977 | METHOD FOR OPTICAL VISUALIZATION OF GRAPHENE DOMAINS - The present invention relates to a method for optical visualization of graphene domains, and more particularly to a method for optical visualization of graphene domains, which can optically visualize the domains and domain boundaries of graphene by forming on a substrate a graphene layer to be measured, forming a liquid crystal layer on the formed graphene layer, and then measuring the optical properties of the formed nematic liquid crystal layer. The method for optical visualization of graphene domains according to the invention uses a liquid crystal-coating method, which is simpler and easier than a conventional method for observing graphene domains. Thus, the method of the invention is simple, time-saving and inexpensive and, at the same time, enables very-large-area graphene domains to be observed with a polarizing microscope or the like. Therefore, the inventive method will be very useful in the research of graphene's properties. | 06-27-2013 |
20130188169 | APPARATUS AND METHODS FOR DETERMINING COMMINGLING COMPATIBILITY OF FLUIDS FROM DIFFERENT FORMATION ZONES - An apparatus and a method including exposing a first fluid to a pre-filter, observing the first fluid, introducing a second fluid to the first fluid, exposing the first and second fluids to a filter, and observing the first and second fluids wherein the observing the first fluid and observing the first and second fluids comprise optical measurements and the first fluid comprises material from a subterranean formation. Some embodiments may compare the optical measurements of the first fluid and the first and second fluids and/or estimate the first fluid's likelihood of forming precipitants with other fluids and/or the first fluid's asphaltene content. An apparatus and method for characterizing a fluid property including a pre-filter in communication with a fluid from a formation, an optical sensor to observe the fluid from the pre-filter, a fluid combination device in communication with the fluid and a second fluid source, a filter in communication with the combination device, a second optical sensor to observe a third fluid from the filter, and a processor to compare data collected by the sensor and second sensor. | 07-25-2013 |
20130265565 | COAL ANALYSIS SYSTEM - A coal analysis system and method includes an extrusion subsystem configured to produce an extrusion from coal samples. An auger drives coal samples through a centering ring producing the extrusion. A LIBS subsystem is configured to analyze the extrusion and an NMR analysis subsystem is downstream of the LIBS subsystem to further analyze the coal. | 10-10-2013 |
20130271748 | DUCT GREASE DEPOSIT DETECTION DEVICES, SYSTEMS, AND METHODS - Automatic devices that determine when pollutant deposits have accumulated in ductwork may be employed to notify maintenance personnel or automated cleaning equipment of the need for ducts to cleaned or replaced. Various detection devices may be employed to detect a property of accumulated grease and generate an indication of an accumulation. The detection device may present a surface to the fume stream inside a duct. The surface may be cooled to a temperature that represents a worst case temperature so that the accumulation due to condensation on the detector surface is at least as high as the coolest surface in the ductwork which is being monitored. Alternatively, the detection device may be located external to the duct. The detection device may interrogate the surface of the duct through contact or noncontact measurements to determine the thickness of an accumulated grease layer on the interior of the duct. | 10-17-2013 |
20130329213 | METHOD FOR MEASURING LIGHT INTENSITY DISTRIBUTION - A method for measuring intensity distribution of light includes a step of providing a carbon nanotube array located on a surface of a substrate. The carbon nanotube array has a top surface away from the substrate. The carbon nanotube array with the substrate is located in an inertia environment or a vacuum environment. A light source irradiates the top surface of the carbon nanotube array, to make the carbon nanotube array radiate a visible light. A reflector is provided, and the visible light is reflected by the reflector. An imaging element images the visible light reflected by the reflector, to obtain an intensity distribution of the light source. | 12-12-2013 |
20140036253 | METHOD AND SYSTEM FOR IMPROVING PRECISION OF ELEMENT MEASUREMENT BASED ON LASER-INDUCED BREAKDOWN SPECTROSCOPY - The present invention provides a method and a system for improving the precision of element measurement based on laser-induced breakdown spectroscopy. The method comprises: press-forming a sample to be measured with a tablet press; making a hole on or immediately above a surface of the press formed sample; forming a layer of aerosol immediately above the surface of the sample to be measured with the components thereof completely identical to those of the sample to be measured; testing the sample to be measured by using a laser-induced breakdown spectroscopic system, so as to obtain the intensities of the characteristic spectral lines of a target element in the sample to be measured; and determining the concentration of the target element in the sample to be measured according to a calibration curve of the target element in prearranged calibration samples. | 02-06-2014 |
20140055773 | METHOD AND DEVICE FOR INSPECTING GLASS SUBSTRATE OF LIQUID CRYSTAL DISPLAY - The present invention provides a method and a device for inspecting glass substrate of liquid crystal display. The method includes (1) providing an inspection device, wherein the inspection device comprises a device body, an operation table mounted on the device body, an irradiation lamp mounted to the device body and located above the operation table, and a steam nozzle mounted to the device body and located above the operation table, the operation table having a bearing surface, the bearing surface forming an included angle with respect to the horizon; (2) positioning a glass substrate-to-be-inspected on the bearing surface; and (3) turning on the irradiation lamp and spraying steam through the steam nozzle toward the glass substrate-to-be-inspected and at the same time, performing visual inspection of the glass substrate to which the steam attaches. | 02-27-2014 |
20140063486 | LASER CONFOCAL SENSOR METROLOGY SYSTEM - The present invention provides apparatus for a non-contact method of obtaining accurate three-dimensional measurements of a dry contact lens, more specifically, using dry lens metrology to know the exact thickness of a contact lens. | 03-06-2014 |
20140098359 | METHOD AND APPARATUS FOR MONITORING A TREATMENT OF A PATIENT, PREFERABLY FOR MONITORING HEMODIALYSIS, HEMODIAFILTRATION, AND/OR PERITONEAL DIALYSIS - The present invention pertains to a method for monitoring a treatment of a patient, preferably for monitoring hemodialysis, hemodiafiltration and/or peritoneal dialysis, the method comprising the steps of irradiating a sample of a dialysis liquid used in the treatment with irradiation light of at least a first irradiation wavelength, detecting light emitted by the irradiated sample in at least a first detection wavelength, the detection wavelength being different from the first irradiation wavelength, and determining the presence and/or concentration of at least one analyte in the sample on the basis of the detected light. | 04-10-2014 |
20140111790 | PRETREATMENT METHOD AND APPARATUS - There is provided a method for performing a pretreatment on an unknown sample including: preparing a plurality of different types of first solutions; adding an unknown sample to the plurality of first solutions and determining whether or not the unknown sample is dissolved; selecting one among the plurality of first solutions in which the unknown sample is dissolved; preparing a plurality of second solution by differentiating concentrations of the selected solution; adding an unknown sample to the second solution and determining whether or not the unknown sample is dissolved; selecting a solution having the lowest concentration in which the unknown sample can be dissolved from among the second solutions; and dissolving the unknown sample by using the solution having the lowest concentration. | 04-24-2014 |
20140160463 | Bubble suppressing system for optical measurement cells - A method and apparatus is disclosed for suppression of bubbles in an optical measurement cell. A measurement cell is filled with a fluid sample. Valves connected through plumbing connections to the cell are operated such that any flow in and out of the cell is stopped. A pressure source is then applied through a valve and flow impedance mechanism to the liquid contained within the cell, causing any bubbles contained or generated within the cell to be dissolved back into solution or reduced in size such that optical measurements taken of the sample are more accurate and free of interference with the measurement beam and of measured stray light. Possible pressure sources include compressed gas, a piston, and a constant flow-rate pump. | 06-12-2014 |
20140192341 | FIXTURE PLANARITY EVALUATION METHOD - Methods for determining the planarity of two components of a semiconductor processing tool, such as a 3D wafer bonder are disclosed. The two components may be fixtures, chucks, or platens of the tool. A test wafer comprising multiple solder balls is compressed and the deformity of multiple solder balls is measured to assess the planarity of the tool. The measurement of the deformed solder balls may be performed manually, or with an automated wafer inspection tool, which may use lasers to measure the height of each solder ball. The planarity of the two components is computed based on the height of the deformed solder balls. | 07-10-2014 |
20140198309 | ENHANCED SCANNING OF TRANSPARENT FIBERS - An apparatus and methods for scanning and measuring transparent fibers. One example method includes placing the transparent fibers on a platen of a flat-bed style scanner and compressing the transparent fibers to the platen with a cover including a non-reflective surface adjacent to the transparent fibers. The method also includes spacing an image sensor apart from a light source on a carriage below the platen and transmitting light from the light source through the platen. The light refracts within the transparent fibers and reflects from the transparent fibers to the image sensor and is absorbed by the non-reflective surface of the cover. The method also includes capturing an image of the transparent fibers with the image sensor. | 07-17-2014 |
20140211196 | ELECTRIC FIELD GENERATING APPARATUS FOR PERFORMING SPECTROSCOPY - According to an example, an apparatus for performing spectroscopy includes a substrate on which a plurality of surface-enhanced spectroscopy (SES) elements are positioned substantially along a first plane. The apparatus also includes a first electrode positioned adjacent to the plurality of SES elements substantially along the first plane and a second electrode positioned adjacent to the plurality of SES elements substantially along the first plane and on a side of the plurality of SES elements that is opposite the first electrode. The first electrode and the second electrode are to generate an electric field around the plurality of SES elements when voltages are applied through the first electrode and the second electrode. | 07-31-2014 |
20140240694 | RAPID TEST METHOD FOR EVALUATING THE DELAMINATION TENDENCY OF GLASS PACKAGING MEANS - A rapid test method for evaluating the delamination in glass packaging is provided. The method includes exposing the glass packaging means to an atmosphere consisting of steam in order to form a corrosion zone; and subsequently carrying out at least one other step. The other step includes: visualizing the corrosion zone using a light microscope; visualizing the corrosion zone by a staining process with a subsequent inspection process; or removing glass components in ultrapure water and quantifying the removed glass components. The rapid test method provides a conclusion about whether a glass packaging exhibits a tendency to delaminate or not in a simple and reliable manner and in a relatively short time span. | 08-28-2014 |
20140320847 | Temporary optical wave diffusion-promoting film adhered to lidded MEMS wafer for testing using interferometer - A temporary optical wave diffusion-promoting film is adhered to a lidded microelectromechanical systems (MEMS) wafer. Testing is performed on the lidded MEMS wafer using an interferometer directed towards the temporary optical wave diffusion-promoting film applied to the lidded MEMS wafer. The temporary optical wave diffusion-promoting film is peeled from the lidded MEMS wafer to remove the temporary optical wave diffusion-promoting film from the lidded MEMS wafer after performing the testing. | 10-30-2014 |
20140362366 | METHOD AND SYSTEM FOR GAS FLOW MITIGATION OF MOLECULAR CONTAMINATION OF OPTICS - A computer-implemented method for determining an optimized purge gas flow in a semi-conductor inspection metrology or lithography apparatus, comprising receiving a permissible contaminant mole fraction, a contaminant outgassing flow rate associated with a contaminant, a contaminant mass diffusivity, an outgassing surface length, a pressure, a temperature, a channel height, and a molecular weight of a purge gas, calculating a flow factor based on the permissible contaminant mole fraction, the contaminant outgassing flow rate, the channel height, and the outgassing surface length, comparing the flow factor to a predefined maximum flow factor value, calculating a minimum purge gas velocity and a purge gas mass flow rate from the flow factor, the contaminant mass diffusivity, the pressure, the temperature, and the molecular weight of the purge gas, and introducing the purge gas into the semi-conductor inspection metrology or lithography apparatus with the minimum purge gas velocity and the purge gas flow rate. | 12-11-2014 |
20150009487 | SKEWED SECTIONAL MEASUREMENT OF STRIATED GLASS - Thickness and group index variations in test strip samples of ultra-low expansion glass are made by extracting the strip samples with front and back faces oriented at an acute skew angle to the axis of the boule. The strip samples are positioned the within an interferometric measurement cavity so that a set of subcavities formed by pairings of each of two reference surfaces together with each of the front and back faces of the strip sample which each subcavity having a different optical path length spacing. The skew angle is sized to avoid diffusion effects of striae present in the boule. | 01-08-2015 |
20150029491 | APPARATUS FOR MICROFLUID DETECTION - A apparatus for microfluid detection for detecting a sample fluid including a plurality of magnetic particles is provided. The apparatus for microfluid detection includes a microfluidic chip and a magnetic generating module. The microfluidic chip includes a substrate and microfluidic channels, wherein the sample fluid is carried by a carry surface of the substrate. The magnetic generating module is adapted for providing a positioning magnetic field and a surrounding magnetic field. The magnetic module controls to move the sample fluid and change a distribution of the magnetic particles in the sample fluid through the positioning magnetic field and the surrounding magnetic field. | 01-29-2015 |
20150042978 | Setting Up a Wafer Inspection Process Using Programmed Defects - Methods and systems for setting up a wafer inspection process using programmed defects are provided. One method includes altering a design for a dummy area of a production chip such that printing of the dummy area on a wafer results in printing of a variety of defects. Two or more of the defects have different types, one or more different characteristics, different contexts in the design, or a combination thereof. The dummy area printed on a wafer may then be scanned with two or more optical modes of an inspection system to determine which of the optical mode(s) are better for defect detection. Additional areas of the wafer may then be scanned with the optical mode(s) that are better for defect detection to determine noise information. The noise information may then be used to select one or more of the optical modes for use in a wafer inspection process. | 02-12-2015 |
20150138532 | MOTION STRATEGIES FOR SCANNING MICROSCOPE IMAGING - Motion strategies in two and three dimensions for scanning microscope imaging are described. An object, sample, or specimen is mounted on a precision three-dimensional stage. The object is moved concurrently with respect to a first axis and a second axis orthogonal to the first against a cutting tool to cut the object. An image of the cut portion is generated as the object is moved. The cutting tool may act as an optical waveguide for illuminating the portion of the object cut. An optical element captures images of the cut and illuminated object. The object may further be concurrently moved with respect to a third axis orthogonal to both the first and second. | 05-21-2015 |
20150323451 | DYNAMIC MEASUREMENT OF DENSITY USING TERAHERTZ RADIATION WITH REAL-TIME THICKNESS MEASUREMENT FOR PROCESS CONTROL - A method of determining a density of a roller compacted ribbon is disclosed. The method comprises compacting dry pharmaceutical powder between press rollers of a roller compactor to produce a compact ribbon. The method also comprises determining a thickness at a point on the compact ribbon in a non-invasive manner after it has rolled out from in between the press rollers. Further, the method comprises passing the compact ribbon through a gap in between the terahertz emitter and the terahertz detector. Next, the method comprises determining a refractive index at the point on the compact ribbon using a measurement value from the terahertz emitter and the terahertz detector and a measured value for the thickness at the point. Finally, the method comprises computing a density of the compact ribbon at the point using a value of the refractive index. | 11-12-2015 |
20150362368 | ELECTRIC FIELD GENERATING APPARATUS FOR PERFORMING SPECTROSCOPY - According to an example, an apparatus for performing spectroscopy includes a substrate on which a plurality of surface-enhanced spectroscopy (SES) elements are positioned substantially along a first plane. The apparatus also includes a first electrode positioned adjacent to the plurality of SES elements substantially along the first plane and a second electrode positioned adjacent to the plurality of SES elements substantially along the first plane and on a side of the plurality of SES elements that is opposite the first electrode. The first electrode and the second electrode are to generate an electric field around the plurality of SES elements when voltages are applied through the first electrode and the second electrode. | 12-17-2015 |
20150377764 | SYSTEM FOR SAMPLING AND/OR ANALYSIS OF PARTICLES IN A GASEOUS ENVIRONMENT - A system for trapping particles in a gas comprising a chamber; an intake for intake of a gas containing at least one particle to be trapped and released, and an outlet for exit of the gas out of the chamber containing at least one particle; a first passage operatively connected to the intake operating to create a flow of a gas containing at least one particle into the chamber, a second passage operatively connected to the outlet for flow of the gas; a third passage operatively connected to a gaseous flow for creating a flow of fluid in a direction substantially opposite to the transfer of gas from the first passage so as to counteract the flow of gas from the first passage; an image sensor for recording an image; and a laser for generating a light beam for forming a photophoretic trap between the first and third passages. | 12-31-2015 |
20160116414 | METHOD AND DETECTOR FOR DETECTING AN ANALYTE - The present disclosure concerns a method and detector ( | 04-28-2016 |
20160161412 | SERS DETECTION SYSTEM FOR CHEMICAL PARTICULATES AND LOW VAPOR PRESSURE CHEMICALS - A method for detecting chemical aerosols and particulates on a surface by contacting a sample with a Surface Enhanced Raman Spectroscopy (SERS) substrate where the sample is an aerosol or a particulate on a surface, encapsulating the SERS substrate with the sample, heating the encapsulated sample so it vaporizes inside the encapsulation, cooling the vaporized sample so it deposits onto the SERS substrate, and irradiating the SERS substrate to collect a SERS spectrum of the sample. Also disclosed is the related system for detecting chemical aerosols and particulates on a surface. | 06-09-2016 |
20160161416 | METHOD OF ACCURATE THICKNESS MEASUREMENT OF BORON CARBIDE COATING ON COPPER FOIL - A method is disclosed of measuring the thickness of a thin coating on a substrate comprising dissolving the coating and substrate in a reagent and using the post-dissolution concentration of the coating in the reagent to calculate an effective thickness of the coating. The preferred method includes measuring non-conducting films on flexible and rough substrates, but other kinds of thin films can be measure by matching a reliable film-substrate dissolution technique. One preferred method includes determining the thickness of Boron Carbide films deposited on copper foil. The preferred method uses a standard technique known as inductively coupled plasma optical emission spectroscopy (ICPOES) to measure boron concentration in a liquid sample prepared by dissolving boron carbide films and the Copper substrates, preferably using a chemical etch known as ceric ammonium nitrate (CAN). Measured boron concentration values can then be calculated. | 06-09-2016 |
20170234788 | SYSTEM AND METHOD FOR DEFORMING AND ANALYZING PARTICLES | 08-17-2017 |
20170234800 | Laser Induced Breakdown Spectroscopy (LIBS) Apparatus for the Detection of Mineral and Metal Contamination in Liquid Samples | 08-17-2017 |
20190145867 | DEVICE AND A METHOD FOR MANAGING A SAMPLE TO BE ANALYZED AND A SOLID SAMPLE CARRIER AND LIQUID SAMPLE CARRIER | 05-16-2019 |
356037000 | Condensation nuclei detector | 3 |
20090009748 | CONDENSATION PARTICLE COUNTER - A condensation particle counter is capable of efficiently measuring the number and size of fine particles. The condensation particle counter includes a saturator, a plurality of condensers and a plurality of optical particle counters. The saturator is designed to generate a saturated gas by saturating a gas in which fine particles are suspended with working fluid. The condensers are connected to a downstream side of the saturator to condense the saturated gas so that liquid droplets can grow around the fine particles. The optical particle counters are connected to downstream sides of the condensers to optically detect the liquid droplets supplied from the condensers. Each of the condensers has a condenser tube for interconnecting the saturator and each of the optical particle counters. The condenser tube is provided with a hydrophilic tube installed inside surface of the condenser tube. | 01-08-2009 |
20090009749 | CONDENSATION PARTICLE COUNTER - A condensation particle counter is capable of efficiently measuring the number and size of fine particles. The condensation particle counter includes a saturator, a condenser and an optical particle counters. The saturator is designed to generate a saturated gas by saturating a gas in which fine particles are suspended with working fluid. The condenser is connected to a downstream side of the saturator to condense the saturated gas so that liquid droplets can grow around the fine particles. The optical particle counter is connected to downstream sides of the condenser to optically detect the liquid droplets supplied from the condensers. The condenser has a condenser tube for interconnecting the saturator and the optical particle counter. The present condensation particle counter can use water as working fluid and also can optically measure fine particles in an easy and accurate manner by forming or installing an inner surface of a condenser tube with a hydrophilic tube. | 01-08-2009 |
20120229795 | DEVICES, METHODS, AND SYSTEMS FOR DETECTING PARTICLES IN AEROSOL GAS STREAMS - Turbulent mixing condensation devices, methods, and systems adapted to condense a working fluid on particles from a sample gas to enlarge the particles for subsequent detection are provided. The device includes a vapor generator adapted to produce a working-fluid saturated carrier gas and a condensation chamber. The working-fluid saturated carrier gas is mixed with a sample gas containing particles to be detected and is then introduced to the condensation chamber. The operating conditions are controlled to enhance the condensation of the working fluid on the particles. The particles are typically forwarded to a particle detection device to detect at least one characteristic, for example, the size, of the particles. The flow of carrier gas to the vapor generator may be regulated to vary the degree of saturation of the carrier gas with working fluid. | 09-13-2012 |
356038000 | Depositing particles on optical surface | 4 |
20090190122 | AERODYNAMIC LENS - An aerodynamic lens, comprises a cylindrical body having an inlet and an outlet; and a convergence-divergence lens portion inside the cylindrical body, having a lens hole formed at the center of the convergence-divergence lens portion, through which a carrier gas and particles pass, a convergence slant surface at a convergence angle (α) with a central axis of the aerodynamic lens at the front of the lens hole, and a divergence slant surface at a divergence angle (β) with the central axis of the aerodynamic lens at the rear of the lens hole. | 07-30-2009 |
20110235021 | METHOD OF DETECTING AN EMULSION IN BRINE - The instant disclosure is directed to a method of detecting an emulsion in a turbid brine, the method comprising the steps of disposing an aliquot of the turbid brine into a sample container to produce a test sample; adding one or more drops of a dye solution comprising an oil-soluble dye dissolved in a nonaqueous base fluid to said test sample; and determining the configuration of the dye solution after a period of time on a surface of the test sample, wherein a configuration of the dye solution forming a ring around the perimeter of the sample container at the interface of a wall of the sample container and the turbid brine indicates an emulsion is present in the turbid brine, and wherein a configuration of the dye solution forming a single dot or a plurality of dots on the surface of the turbid brine indicates an emulsion is not present in the turbid brine. | 09-29-2011 |
20140028995 | INTEGRATED SENSORS - Examples of integrated sensors are disclosed herein. An example of an integrated sensor includes a flexible substrate, and an array of spaced apart sensing members formed on a surface of the flexible substrate. Each of the spaced apart sensing members includes a plurality of polygon assemblies. The polygon assemblies are arranged in a controlled pattern on the surface of the flexible substrate such that each of the plurality of polygon assemblies is a predetermined distance from each other of the plurality of polygon assemblies, and each of the plurality of polygon assemblies including collapsible signal amplifying structures controllably positioned in a predetermined geometric shape. | 01-30-2014 |
20140204364 | METHODS FOR MAKING AND COMPOSITIONS OF TWO DIMENSIONAL PARTICLE ARRAYS - A method of preparation of a 2-D array of particles comprising: mixing the particles and a first liquid, the first liquid having the properties of being soluble in water and reducing surface tension of a water surface; adding the mixture to the water surface; and transferring the 2-D array onto a solid surface. A composition comprising: a 2-D array of particles; and a polymer substantially enveloping the 2-D array of particles. | 07-24-2014 |