Class / Patent application number | Description | Number of patent applications / Date published |
204455000 | Using gel-filled capillary | 13 |
20090211907 | Separation Medium for Biochemical Analysis - The invention provides a novel packing composition for separation and/or analysis which permits easy capillary replacement; a process for the production of the packing composition; a method for filling a capillary with the packing composition; and electrophoretic methods (such as capillary electrophoresis) with the same. The invention relates to a packing composition for electrophoretic separation and/or analysis which contains a long self-assembly produced by dissolving a low-molecular-weight amphiphilic compound having a hydrophobic moiety and a hydrophilic moiety in water under heating and then cooling the resulting solution; a process for the production of the packing composition; a method of separation and/or analysis with the composition; and so on. | 08-27-2009 |
20090277790 | INDIVIDUAL IDENTIFICATION METHOD AND APPARATUS - An individual identification method for identifying an individual by analyzing a DNA sample through electrophoresis, comprises: a first analysis step of analyzing an identifier-attached DNA sample which is given an identifier for an individual; a step of storing a result obtained by analyzing the identifier-attached DNA sample together with a corresponding identifier in a database; a second analysis step of analyzing a new sample which is a DNA sample subjected to individual identification with an accuracy lower than the accuracy when the identifier-attached DNA sample is analyzed, and using the result as a new sample analysis result; and a step of searching the database based on the new sample analysis result. | 11-12-2009 |
20090288951 | Method for Automated High Throughput Identification of Carbohydrates and Carbohydrate Mixture Composition Patterns as well as Systems Therefore - The present invention relates to methods for the identification of compounds in carbohydrate mixture compositions as well as the determination of carbohydrate mixture composition patterns, based on e.g. orthogonal cross determining migration time (indices) using capillary gel electrophoresis-laser induced fluorescence and identifying said carbohydrate components based on comparing said migration time (indices) with standard migration time (indices) from a database which data are preferably also orthogonal cross determined. In a further aspect, the present invention relates to a method for carbohydrate mixture composition pattern profiling, like glycosylation pattern profiling using capillary gel electrophoresis-laser induced fluorescence (CGE-LIF). In another aspect, the present invention refers to a system for an automated determination and/or identification of carbohydrates and/or carbohydrate mixture composition patterns (e.g.: glycosylation patterns). Finally, the present invention relates to a database containing e.g. orthogonal cross normalized migration times and/or migration time indices of carbohydrates. | 11-26-2009 |
20090314638 | Methods and Compositions for Capillary Electrophoresis - This invention relates to improved methods and compositions for conducting Capillary Electrophoresis (CE) to separate molecules on the basis of their respective size or charge. | 12-24-2009 |
20100025243 | METHOD FOR ROBUST CONTROL OVER A SOLUABLE FACTOR MICROENVIRONMENT WITHIN A THREE-DIMENSIONAL GEL MATRIX - A method is provided of generating a gradient within gel matrix received in a channel of a microfluidic device. A source reservoir in communication with the input of the channel is filled with a first fluid. A sink reservoir in communication with the output of the channel is filled with a second fluid. A soluble factor is deposited in the source reservoir such that the soluble factor diffuses into the channel and forms the gradient. The soluble factor in source reservoir is replenished to maintain the gradient in a generally pseudo-steady state and the second fluid in the sink reservoir is replaced. | 02-04-2010 |
20100300880 | CAPILLARY TWO- OR MULTI-DIMENSIONAL ELECTROPHORESIS IN A SINGLE CAPILLARY - The present invention relates to a method for separating the components of a mixture M by electrophoresis in a single capillary, wherein: (A) the compounds of the mixture M are introduced and migrate inside the capillary according to the capillary electrophoresis technique; (B) a fraction F of the compounds separated in step (A) is isolated in the capillary and said isolated fraction F is forced to migrate towards the vicinity of one end of the capillary while maintaining this fraction inside the capillary; (C) upon the application of a pressure difference between the ends of the capillary, a second separation medium MS | 12-02-2010 |
20110031120 | GEL COMPOSITION - A gel composition for use in electrophoresis analysis of proteins, characterised in that the gel composition includes a polar solvent as an additive, wherein the polar solvent is one of either an alcohol or a formamide derivative. Methods of use, methods of manufacture and apparatus including the gel composition described hereinabove are also provided. | 02-10-2011 |
20120000779 | SURFACE ACOUSTIC WAVE SENSOR DEVICE INCLUDING TARGET BIOMOLECULE ISOLATION COMPONENT - Provided herein is a surface acoustic wave (“SAW”) sensor device including an isolation component of a target biomolecule. A sample containing the target biomolecule is separated by its size using electrophoresis, and sequentially reacts with a SAW sensor. In other words, the device is capable of detecting the target biomolecule by separating biomolecules using electrophoresis, and applying the separated biomolecules to the SAW sensor. | 01-05-2012 |
20120000780 | Physically Crosslinked Copolymer Compounds and Related Compositions and Methods for Electrophoretic Separation - Linear acrylamide copolymer compounds which can comprise monomeric components comprising at least one N-substituted moiety capable of physical cross-linking, and related compositions and methods of use. | 01-05-2012 |
20120267246 | METHODS AND APPARATUS FOR IMPROVING THE SENSITIVITY OF CAPILLARY ZONE ELECTROPHORESIS - The present invention relates to novel methods and apparatus for improving the sensitivity of capillary zone electrophoresis (CZE). The invention particularly concerns devices comprising a channel that contains an in-line sol-gel column to concentrate samples being subjected to capillary zone electrophoresis, and the use of such devices to enhance the sensitivity of capillary zone electrophoresis. | 10-25-2012 |
20130213811 | MICROSCALE WESTERN BLOT - Systems and methods are provided for integrating the electrophoresis and blotting of samples. A capillary electrophoresis and blotting system allows concomitant electrophoretic separation and blotting to provide a rapid and simplified process. A microfluidic electrophoresis and blotting system provides electrophoretic separation in a microfluidic channel followed by electroblotting from the microfluidic channel to also provide a rapid and simplified process. These systems and methods can be used to assay smaller amounts of sample in less time than conventional processes, including conventional Western blotting techniques. | 08-22-2013 |
20130248366 | METHODS AND APPARATUS FOR AMPLIFYING NUCLEIC ACIDS - A method of amplifying nucleic acid includes providing a microfluidic device having a space therein. The space is filled with a gel medium. Reagents for carrying out a PCR reaction are supported within the matrix of the gel medium within the space. A nucleic acid containing sample is brought into contact with the gel medium. The sample having whole cells or cell lysate without any prior separation of the nucleic acid from other components of the cells. PCR amplification of nucleic acid from the sample is performed in the space using the PCR reagents. | 09-26-2013 |
20140332383 | FREE-STANDING MICROFLUIDIC GEL ELECTROPHORESIS DEVICES AND METHODS - Provided are devices that include a support, a free-standing polymeric separation medium associated with the support and configured to separate a sample along a directional axis, and a sample-loading element associated with the polymeric separation medium. Systems that include the devices, as well as methods of using the devices, are also provided. Embodiments of the present disclosure find use in a variety of different applications, including detecting whether an analyte is present in a fluid sample. | 11-13-2014 |