University of Rochester Medical Center Patent applications |
Patent application number | Title | Published |
20130288976 | Methods for Determining the Presence or Risk of Developing Facioscapulohumeral Dystrophy (FSHD) - In one aspect, the invention provides a method of screening a human subject to determine if said subject has a genetic predisposition to develop, or is suffering from Facioscapulohumeral Dystrophy (FSHD), said method comprising: (a) providing a biological sample comprising genomic DNA from the subject; and (b) analyzing the portion of the genomic DNA in the sample corresponding to the distal D4Z4-pLAM region on chromosome 4 and determining the presence or absence of a polymorphism resulting in a functional polyadenylation sequence operationally linked to exon 3 of the DUX4 gene, wherein a determination of the absence of a functional polyadenylation sequence operationally linked to exon 3 of the DUX4 gene indicates that the subject does not have a genetic predisposition to develop, and is not suffering from FSHD, and/or wherein a determination of the presence of a functional polyadenylation sequence operationally linked to exon 3 of the DUX4 gene indicates that the subject has a genetic predisposition to develop, or is suffering from Facioscapulohumeral Dystrophy (FSHD). | 10-31-2013 |
20100160174 | PROTEIN TRANSDUCING DOMAIN/DEAMINASE CHIMERIC PROTEINS, RELATED COMPOUNDS, AND USES THEREOF - Disclosed are compositions for chimeric proteins comprising a protein transduction domain and a deaminase domain, mimetics or analog thereof, and uses of same. | 06-24-2010 |
20090325235 | THERMOACTIVE SIVagm SAB REVERSE TRANSCRIPTASE - Methods and kits performing reverse transcription and RT-PCR reactions having high fidelity, processivity and DNA polymerase activity are described. The methods involve performance of reverse transcription at an increased temperature with a reverse transcriptase from Simian Immunodeficiency Virus-agm.sab or a variation thereof. The kits of the present invention include a reverse transcriptase from Simian Immunodeficiency Virus-agm.sab or a variation thereof, a DNA polymerase capable of amplifying cDNA under conditions suitable for polymerase chain reaction, and the reagents necessary to carry out both processes. | 12-31-2009 |
20090290766 | Automated placental measurement - A method for analyzing the placenta and histology slides of placental tissue comprising: selecting a placental sample to be analyzed; obtaining a digital image of the placental sample; and performing an analysis on the digital image, wherein a mathematical algorithm is applied to the digital image. The results of the analysis are correlated with data on health outcomes in infants, children, or adults and are used to assess future physiological risks to a patient. | 11-26-2009 |
20090282496 | Androgen Receptor Related Methods for Treating Bladder Cancer - Disclosed are compositions and methods for treating bladder cancer. | 11-12-2009 |
20080249400 | Intraoperative Imaging Of Hepatobiliary Structures - The invention provides methods for visualizing hepatobiliary structures, or lesions in a liver, intraoperatively by use of fluorescent dyes. | 10-09-2008 |