Universite Joseph Fourier- Grenoble 1 Patent applications |
Patent application number | Title | Published |
20150293090 | RECOMBINANT GRA ANTIGENS AND THE USE OF SAME FOR EARLY DIAGNOSIS OF TOXOPLASMOSIS - The present disclosure relates to a method for identifying the presence or absence of anti- | 10-15-2015 |
20150289755 | MULTI-VIEW IMAGING SYSTEM FOR LAPAROSCOPIC SURGERY - The invention concerns a multi-view imaging system for laparoscopic surgery comprising: A tubular member; A first imaging device having a longitudinal body and an active end for acquiring images, intended to be inserted through the tubular member, and movable in the tubular member in translation along the longitudinal axis and/or in rotation about the longitudinal axis; A second imaging device comprising at least two cameras each mounted on a support member and movable relative to the tubular member between: a stowed position in which the cameras are positioned inside the tubular member, and a deployed position in which the cameras are positioned outside the tubular member at the distal end, the cameras being arranged on either side of the longitudinal axis of the tubular member and being held secure relative to the tubular member by holding means, so as to follow any movement of the tubular member. | 10-15-2015 |
20150283247 | GLUCOSE RESPONSIVE HYDROGEL COMPRISING PBA-GRAFTED HYALURONIC ACID (HA) - Polymer composition comprising a mixture of PBA modified HA polymer grafted on at least a hydroxyl with a group comprising phenylboronic acid and Cis-diol modified HA polymer grafted on at least a hydroxyl with a group comprising a cis-diol. Injectable or implantable glucose-sensitive hydrogels comprising a this polymer composition. | 10-08-2015 |
20150137682 | GLOW DISCHARGE LAMP - The disclosure includes a glow-discharge lamp including: an elongate casing transparent to illuminating radiation and containing a plasma gas; a device for applying an electric field for maintaining a plasma in the so-called positive column region of the casing, the device including two electrodes forming an anode and a cathode located in the casing at each end thereof; and a radio-frequency or microwave cathode plasma source arranged in the casing in relation to the cathode-forming electrode, such as to generate a high-frequency discharge located on the surface of the electrode in order to generate the plasma. The disclosure also includes a lighting method of such a glow-discharge lamp. | 05-21-2015 |
20150126880 | METHOD AND DEVICE FOR MONITORING BLOOD PRESSURE MEASUREMENT BY ARTERIAL CATHETERIZATION OF A PATIENT - A method is disclosed for continuously monitoring a blood pressure measurement using a sensor connected by a hydraulic link to an arterial catheter, the method includes determining the dynamic parameters of the link, analyzing the frequency content of the incident signal, detecting one of the following situations: (a) ability of the link to transmit the incident signal with a distortion below a threshold, (b) ability of the link to transmit the incident signal with a distortion above the threshold and possibility of correcting the measured signal, (c) inability of the link to transmit the incident signal with a distortion below the threshold and impossibility of correcting the measured signal, periodic application of a mechanical action to the tubing providing the hydraulic link. | 05-07-2015 |
20150044201 | CYCLON EXPRESSION FOR THE IDENTIFICATION AND CONTROL OF CANCER CELLS - The present disclosure concerns a method for the identification of the presence or absence of cancer cells in a biological sample, more particularly a method for the identification of the susceptibility or resistance to a treatment with CD20 agonists of cancer cells in a biological sample, the methods including determining the level of expression of the gene Cyclon in the cells and comparing the level of expression to the level of expression in a non-cancer cell, wherein a level of expression higher than the level of expression in a non-cancer cell is an indication of the presence of a cancer cell, more particularly an indication of cancer cells with a resistance to treatment with antagonists. Kits for the determination of a level of expression of the Cyclon gene in a biological sample, a method for the identification of Cyclon expression antagonists, and methods for treating patients are provided. | 02-12-2015 |
20140335125 | ATTENUATED AND ADAPTED STRAIN OF PSEUDOMONAS FOR DELIVERING ANTIGENS - A process for obtaining an adapted strain of | 11-13-2014 |
20140315232 | METHOD FOR DOSING THE CONTROL CAPACITY OF C1INH - The present invention relates to a method for dosing the control capacity of plasma serpin (SERine Protease INhibitor) C1 inhibitor (C1Inh) on the basis of a patient blood sample. The invention also relates to a kit specially designed for said dosing. | 10-23-2014 |
20140255303 | ANTI-VCAM-1 NANOBODIES - The present invention relates to nanobodies specifically directed against VCAM-1 and to their use in medical imaging and in diagnostic, prognostic and treatment methods. | 09-11-2014 |
20140051099 | DIAGNOSIS AND TREATMENT OF ANGIOEDEMA - The present patent application relates to a method for diagnosing angioedema with a gain-of-function mutation of kinin formation, and for determining the amount of BK or des-Arg | 02-20-2014 |
20140050716 | NOVEL PROCOAGULANT MOLECULAR DECOY FOR TREATING HEMOPHILIA A OR B WITH OR WITHOUT INHIBITOR - The present invention relates to a pharmaceutical composition including a modified factor Xa (GDXa), said modified GDXa being nonthrombogenic, able to bind to TFPI but not able to bind to phospholipids, for preventing or treating a hemorrhagic accident in a patient with hemophilia A or B with or without inhibitor. | 02-20-2014 |
20130231474 | POLYSACCHARIDE DERIVATIVES INCLUDING AN ALKENE UNIT AND THIOL-CLICK CHEMICAL COUPLING REACTION - The invention relates to polysaccharides grafted with a unit including a carbon-carbon double bond, to polysaccharides grafted with a unit including a carbon-carbon double bond functionalized by a thioether unit, to the methods for preparing said compounds, to the compositions including such compounds and to the materials including such materials or compositions. | 09-05-2013 |
20130199439 | DEVICE AND METHOD FOR CRYSTALLIZING INORGANIC OR ORGANIC SUBSTANCES - A device for crystallising a molecule to be crystallised, which includes: at least one crystallisation cell that includes a crystallisation chamber for receiving a first solution S1 containing the molecule to be crystallised and the crystal seeds thereof, a dialysis membrane, and a container to be filled with a second solution S2 that contains constituents selected from the group containing crystallisation agents, additives and buffers; and at least one image acquisition means. The crystallisation device is characterized in that it includes: at least one addition means arranged to add, to the container, constituents selected from the group containing crystallisation agents, additives and buffers of solution S2; and/or at least one sampling means arranged to collect, from the container, all or a portion of solution S2. The invention also relates to a crystallisation method. | 08-08-2013 |
20130130394 | DEVICES AND METHODS FOR CONTROLLING ACTIN FILAMENTS GROWTH AND ORGANIZATION USING MICROPATTERNED NUCLEATION SITES - The present invention concerns devices and methods for controlling actin filaments growth and organization with micro patterned nucleation sites, their uses for studying actin network formation, for screening of drugs or for preparing complex structures. | 05-23-2013 |
20130041478 | SYSTEM AND METHOD FOR MANAGING SERVICES IN A LIVING PLACE - A system is provided for managing services in a living place, including:
| 02-14-2013 |
20120283126 | HUMAN FERTILITY TEST USING DPY19L2 - The present patent application concerns a method for diagnosing infertility related to the DPY19L2 protein, in a male human subject, and a method for treating said subject with a view to restoring fertility. The present invention also concerns the use of molecules inhibiting the action of the DPY19L2 polypeptide in a wild-type carrier male subject, for example of anti-DPY19L2 interfering nucleic acid type selectively inhibiting the expression of the DPY19L2 polypeptide. | 11-08-2012 |
20120172753 | SURGICAL INSTRUMENT FOR MOLECULAR SAMPLING - The present disclosure relates to a surgical instrument for sampling molecules in an organ which can be accessed directly or via a surgical portal, including:
| 07-05-2012 |
20120125486 | METHOD AND DEVICE FOR TREATING A MATERIAL EXPOSED TO A MAGNETIC FIELD - The disclosure concerns a method for treating a material in a static magnetic field having an intensity of more than 1 Tesla, including the following steps:
| 05-24-2012 |
20120034593 | CYCLIC PEPTIDES WITH AN ANTI-PARASITIC ACTIVITY - The present invention relates to a method for preparing a cyclic peptide with antiparasite activity and anticancer activity. The invention also relates to this peptide as an antiparasite agent, for example in the treatment of toxoplasmosis and as an anticancer agent. The invention also relates to the use of this cyclic peptide for treating organs ex vivo before transplantation. | 02-09-2012 |
20110257514 | IMAGE PROCESSING METHOD FOR ESTIMATING A BRAIN SHIFT IN A PATIENT - The disclosure relates to an image processing method for estimating a brain shift in a patient, the method involving: the processing of a three-dimensional image of the brain of a patient, acquired before a surgical operation, in order to obtain a reference cerebral arterial tree structure of the patient; the processing of three-dimensional images of the brain of the patient, acquired during the operation, in order to at least partially reconstitute a current cerebral arterial tree structure of the patient; the determination from the combination of the reference and current cerebral arterial tree structures, of a field of shift of the vascular tree representing the shift of the current vascular tree in relation to the reference vascular tree; the application of the determined field of shift of the vascular tree to a biomechanical model of the brain of the patient in order to estimate the brain shift of the patient; and the generation, from the estimated brain shift, of at least one image of the brain of the patient, in which the brain shift is compensated. | 10-20-2011 |
20110237551 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions - The invention relates to the use of para-coumaric acid or para-hydroxycinnamic acid derivatives in cosmetic or dermatological compositions, specifically to the use of at least one compound derived from para-coumaric acid having a general formula (I) below: | 09-29-2011 |
20110215722 | DEVICE AND METHOD FOR PRODUCING AND/OR CONFINING A PLASMA - The invention relates to a device for producing and/or confining a plasma ( | 09-08-2011 |
20110176746 | METHOD FOR REGISTERING A SET OF POINTS IN IMAGES - The disclosure relates to an image processing method for estimating a brain shift in a patient, the method involving: the processing of a three-dimensional image of the brain of a patient, acquired before a surgical operation, in order to obtain a reference cerebral arterial tree structure of the patient; the processing of three-dimensional images of the brain of the patient, acquired during the operation, in order to at least partially reconstitute a current cerebral arterial tree structure of the patient; the determination from the combination of the reference and current cerebral arterial tree structures, of a field of shift of the vascular tree representing the shift of the current vascular tree in relation to the reference vascular tree; the application of the determined field of shift of the vascular tree to a biomechanical model of the brain of the patient in order to estimate the brain shift of the patient; and the generation, from the estimated brain shift, of at least one image of the brain of the patient, in which the brain shift is compensated. | 07-21-2011 |
20110137330 | SURGICAL INTERVENTION DEVICE COMPRISING AN INSTRUMENT LIKELY TO DEFORM - The disclosure relates to a surgical intervention device, including a surgical instrument capable of passing through human or animal tissue and a system comprising so-called “passive” components capable of measuring deformation or a local strain of the instrument and/or so-called “active” components capable of imposing a local strain on the instrument, the system comprising at least two series of passive components arranged at the surface of the instrument so as to establish a biunivocal relation between the position of the instrument or the position of the distal end of the instrument and all the data originating from the series, and, where required, at least two series of active components arranged at the surface of the instrument. The disclosure also relates to a process for determining the position of the distal end of a surgical instrument capable of passing through human or animal tissue. | 06-09-2011 |
20110130659 | Imaging System for Following a Surgical Tool in an Operation Field - The invention concerns an imaging system to monitor at least one surgical instrument in an operative site inside a volume of the body of an animal, comprising:
| 06-02-2011 |
20110130299 | PLASTIDIAL MICROARRAY - The present invention relates to a plastidial microarray comprising a solid support which comprises a multiplicity of elemental sites, each elemental site comprising several copies of the same nucleic acid probe, said probe being single-stranded, comprising between 50 and 70 nucleotides and corresponding to a sense oligonucleotide in a chloroplastid gene of | 06-02-2011 |
20110126844 | DEVICE FOR POSITIONING A SURGICAL TOOL IN THE BODY OF A PATIENT - The present disclosure relates to a device for positioning and/or orienting, in the body of a patient, a surgical tool carried by a tool-holder, including a platform capable of being placed on the body of the patient, an orientable carrier, at least one part of which is rigidly connected to the tool-holder, means for guiding the orientable carrier rotationally relative to the platform in two directions of a plane parallel to the platform, at least 2 pneumatic actuators which engage with the orientable carrier such that a variation in pressure of at least one of the pneumatic actuators causes the orientable carrier to rotate in the first direction and/or the second direction, in which the pneumatic actuators are volumes that can deform in a predetermined direction as a function of the internal pressure. | 06-02-2011 |
20110122229 | Imaging System for Three-Dimensional Observation of an Operative Site - The invention relates to an endoscopic imaging system for observation of an operative site ( | 05-26-2011 |
20110046476 | SYSTEM AND METHOD FOR ANALYSING A SURGICAL OPERATION BY ENDOSCOPY - The invention relates to a method for analysing a surgical operation by endoscopy in an operation field in a space inside the body of an animal, characterised in that it comprises the steps of: detecting at least one tool ( | 02-24-2011 |
20100204177 | PROCESS FOR PREPARING THERMOSENSITIVE (POLY(ETHYLENE OXIDE) POLY(PROPYLENE OXIDE)) DERIVATES THAT CAN BE USED TO FUNCTIONALIZE CHITOSAN - The invention relates to a thermosensitive (poly(ethylene oxide) poly(propylene oxide))-acetal derivative, which can be used to functionalize chitosan, and to the process for the preparation thereof. The invention therefore also relates to a process for functionalizing chitosan by grafting this thermosensitive copolymer and optionally another thermosensitive polymer, poly(ethylene oxide). A subject of the invention is also a chitosan-(poly(ethylene oxide) poly(propylene oxide))-poly(ethylene oxide) derivative which has the advantage of being water-soluble at physiological pH. The invention therefore also relates to the aqueous compositions comprising this derivative and to the use of this composition for the manufacture of gel by heating. | 08-12-2010 |
20100178592 | BIOMIMETIC ARTIFICIAL MEMBRANE DEVICE - The invention relates to a device comprising a casing and a biomimetic artificial membrane arranged within the casing to form two distinct chambers, wherein each chamber is provided for enclosing a liquid of a given composition, and wherein the biomimetic artificial membrane comprises a semi-permeable membrane for supporting a lipid membrane, the lipid membrane comprising a plurality of lipid molecules arranged in a layer and including at least a transport protein, the transport protein being adapted for transport of ions and/or molecules of the liquids between the two chambers. | 07-15-2010 |
20100075917 | THIONUCLEOSIDES AND PHARMACEUTICAL APPLICATIONS - The invention relates to a pharmaceutical composition containing as an active ingredient at least one compound selected from the compounds of the formula (II), in which the S atom is bonded to the nucleoside carbon at T or to the nucleoside carbon at 3′, and from the compounds of the following formula (III): formulae in which B is a nucleotide natural or modified base, x is 0, 1 or 2, and R1 and R represent a carbonated group or a molecular hydrocarbon remnant that can be substituted and/or interrupted by one or more atoms and/or by one or more groups containing one or more atoms, said atoms being selected from N, O, P, S, Si, X where X is halogen. The invention also relates to pharmaceutically acceptable carrier. | 03-25-2010 |
20090264637 | PROCESS FOR PREPARING DISULPHIDES AND THIOSULPHINATES AND COMPOUNDS PREPARED - Process for preparing a compound of the formula (I) R1-S(O) | 10-22-2009 |
20080242738 | Hydrogel Functionalized with a Polymerizable Moiety and Their Uses as Biosensors or Bioreactors - The present invention relates to a new hydrogel functionalized with a polymerizable moiety, the polymerized hydrogels, films and gels comprising the same and their use for cells, proteins, DNA or other molecules encapsulation, including use as biosensors or bioreactors. | 10-02-2008 |