Universite Catholique de Louvain Patent applications |
Patent application number | Title | Published |
20150136192 | Thermoelectric Conversion Module and Method for Making it - According to a first aspect, the invention relates to a thermoelectric module ( | 05-21-2015 |
20150115019 | Method for Welding at Least Two Layers - The method of the invention relates to a method for welding a first ( | 04-30-2015 |
20150048541 | METHOD FOR EXTRUDING A POLYMER IN THE PRESENCE OF WATER - The invention relates to a method for converting a polycondensed elastomeric thermoplastic polymer, including a step of extruding the polycondensed elastomeric thermoplastic polymer in the presence of water. The polycondensed elastomeric thermoplastic polymer is in particular chosen from copolymer block amides, copolyethers or copolyester block urethanes, copolyether block esters and the mixtures thereof, and is preferably a copolyether block amide. | 02-19-2015 |
20150037291 | COMPOSITIONS AND METHODS FOR CELL TRANSPLANTATION - The present invention relates to compositions and methods for cell transplantation. In particular, the present invention provides a composition comprising procoagulant cells and at least one factor Xa inhibitor, preferably rivaroxaban, as well as at least one thrombin inhibitor, preferably bivalirudin. | 02-05-2015 |
20140286917 | ISOLATED LIVER STEM CELLS - Isolated liver progenitor stem cells and cell populations of isolated liver progenitor stem cells are disclosed. The progenitor stem cells originate from adult liver, especially human adult liver. The isolated progenitor stem cells have uses in medicine, hepatology, inborn errors of liver metabolism transplantation, infectious diseases and liver failure. Methods of isolating these cells and their culture is described. The isolated cells are characterized before and after differentiation. Their use for transplantation and as animal models of human disease, toxicology and pharmacology is disclosed. | 09-25-2014 |
20140243241 | METHOD FOR MEASURING BETA-LACTAM ANTIBIOTICS - The present invention relates to methods for determining the concentration of a free beta-lactam antibiotic in a biological sample. In particular, the present invention relates to methods for measuring a free beta-lactam antibiotic in a biological sample, comprising the steps of: (a) providing at least one class C beta-lactamase, a functional fragment or variant thereof; (b) providing at least one biological sample; (c) contacting said at least one class C beta-lactamase with said at least one biological sample; and (d) determining the concentration of said free beta-lactam antibiotic in said at least one biological sample. | 08-28-2014 |
20140179973 | METHOD OF OLEFIN METATHESIS USING A CATALYST BASED ON A SPHERICAL MATERIAL COMPRISING OXIDISED METAL PARTICLES TRAPPED IN A MESOSTRUCTURED MATRIX - A process for metathesis of olefins, bringing olefins into contact with a catalyst activated by heating to a temperature in the range 100° C. to 1000° C. in an atmosphere of non-reducing gas, the catalyst containing at least one inorganic material having at least two elementary spherical particles, each of which are metal oxide particles with a size of at most 300 nm and containing at least one of tungsten, molybdenum, rhenium, cobalt, tin, ruthenium, iron or titanium, alone or a mixture, the metal oxide particles being present within a mesostructured matrix of an oxide of at least one element Y: silicon, aluminium, titanium, tungsten, zirconium, gallium, germanium, tin, antimony, lead, vanadium, iron, manganese, hafnium, niobium, tantalum, yttrium, cerium, gadolinium, europium or neodymium or a mixture thereof, the matrix having pore size 1.5 to 50 nm and amorphous walls with thickness 1 to 30 nm and maximum diameter of 200 μm. | 06-26-2014 |
20140163283 | METHOD OF CARRYING OUT CC-COUPLING REACTIONS USING OXIDE SUPPORTED PD-CATALYSTS - A method of carrying out Suzuki-Miyaura CC-coupling reactions, includes reacting an aryl halide with an aryl boronic acid in an organic solvent in the presence of an oxide supported palladium catalyst and a base, characterized in that the base is added in the form of an aqueous solution with a constant flow rate within a predetermined period of time at the beginning of the reaction. | 06-12-2014 |
20140127676 | ISOLATED LIVER STEM CELLS - A method of conducting in vitro toxicity testing is disclosed which includes the steps of exposing to a test agent a population of human liver progenitor or stem cells originated from human adult liver. The cells have the characteristics that the isolated human progenitor or stem cells express at least the mesenchymal markers vimentin and α-smooth muscle actin (ASMA), the hepatocyte marker albumin (ALB), are negative for cytokeratin-19 (CK-19), and have mesenchymal-like morphology. One or more effects, if any, of the test agent on the population of human liver progenitor or stem cells are observed. Also disclosed are methods of conducting in vitro drug metabolism studies by exposing to a test agent a population of the human liver progenitor or stem cells and methods of testing infected human liver progenitor or stem cells for effects of a test agent. | 05-08-2014 |
20140019050 | METHOD AND DEVICE FOR CHARACTERIZATION OF PHYSICAL PROPERTIES OF A TARGET VOLUME BY ELECTROMAGNETIC INSPECTION - The method of the invention comprises the following steps: positioning a field source ( | 01-16-2014 |
20130336940 | MODIFIED PIG ISLETS FOR DIABETES TREATMENT - The present invention relates to a modified pig islet capable of producing higher levels of glucagon than a native pig islet or capable of producing a glucagon analog, and methods for obtaining thereof. The invention also relates to a method for treating Diabetes Mellitus, and/or for regulating blood glucose levels in a subject in need thereof, comprising the administration of the modified pig islets of the invention. | 12-19-2013 |
20130302291 | COMPOSITIONS AND METHODS FOR CELL TRANSPLANTATION - The present invention relates to compositions and methods for cell transplantation. In particular, the present invention provides a composition comprising procoagulant cells and at least one antithrombin activator, preferably unfractionated heparin, as well as at least one thrombin inhibitor, preferably bivalirudin. | 11-14-2013 |
20130297040 | IMPLANT HAVING A CORE AND A TUBE ENCASING THE CORE - The present invention relates to an implant comprising: —a core material comprising polydimethylsiloxane or at least one hydrogel polymer; —a tube encasing said core material comprising an ethylene vinyl acetate polymer or at least one hydrogel polymer; —a sealant for closure of the open ends of said tube comprising polydimethylsiloxane or a mono-, di-, or triacetoxy derivative thereof, or at least one hydrogel polymer; and —at least one active ingredient; wherein said at least one active ingredient is selected from the group comprising celecoxib, sulindac, tamoxifen, oestrogen, oestradiol, ethinyl oestradiol, mestranol, dienogest, norgestrel, levonorgestrel, desogestrel, norgestimate, ethynodiol diacetate, leuprorelin, buserelin, gonrelin, triptorelin, nafarelin, deslorelin, histrelin, and supprelin; and with the proviso that when the sealant is said at least one hydrogelpolymer, the core material comprises polydimethylsiloxane. Furthermore, the invention relates to an implant for use as a medicament. In particular, the invention relates to an implant for use in the treatment of endometriosis. | 11-07-2013 |
20130289321 | METHOD OF CARRYING OUT CC-COUPLING REACTIONS - The present invention is directed to a method of carrying out Suzuki-Miyaura CC-coupling reactions, including reacting an aryl halide with an aryl boronic acid in an organic solvent in the presence of a carbon supported palladium catalyst and a base, wherein the reactions are carried out at constant pH. The invention is also directed to a palladium on carbon catalyst suitable for catalyzing Suzuki-Miyaura CC-coupling reactions. | 10-31-2013 |
20130289030 | NOVEL PHENAZINE DERIVATIVES AND THEIR USES - The present invention is directed to novel compounds of formula I | 10-31-2013 |
20130121747 | PENCILS, METHOD OF PREPARATION AND USE - The present invention relates to a pencil comprising a core within a barrel, wherein the band composition consists of (a) at least one styrene-butadiene copolymer, (b) at least one styrene-butadiene-styrene block copolymer, (c) at least one polymer selected from the group consisting of styrene polymer, styrene-acrylonitrile polymer, acrylonitrile-butadiene-styrene polymer, acrylic-styrene-methylmethacrylate copolymer, or a combination thereof; and optionally (d) at least one additive selected from the group consisting of a filler, a wax, a porogen, a blowing agent, a foaming agent, a coloring agent, or a combination thereof. The present invention also relates to a method for the preparation of said pencil and to the use thereof. | 05-16-2013 |
20130096911 | NORMALISATION OF NOISY TYPEWRITTEN TEXTS - Described herein is a method and system for normalising a SMS sequence in which the sequence is pre-processed to identify noisy segments in the sequence, normalising those noisy segments and normalising the rest of the SMS sequence in accordance with predefined rules. A morphosyntactic analysis is carried out on the normalised text before an output is provided either as a typewritten text or as a synthetic speech signal. | 04-18-2013 |
20120298530 | SMART SENSOR SYSTEM USING AN ELECTROACTIVE POLYMER - A system for measuring a solution pH includes a potentiostat with a working electrode made of an electro-conductive solid polymer transducer, an input to receive the potential to be applied between the working electrode and a reference electrode, and an output to transmit a signal representative of the current flowing between a counter electrode and the working electrode, the three electrodes being immerged into the solution. The system further includes a digital processor connected to a digital to analog converter for generating the potential to be applied between the working and the reference electrodes; and to an analog to digital converter for receiving a digital value representative of the current. The digital processor is adapted to modify the potential to maintain the current inside a predetermined range such that the potential is representative of the solution pH when the current is inside the predetermined range. | 11-29-2012 |
20120289418 | DIAGNOSTIC METHOD AND KIT FOR THE DETECTION OF A LYMPHOCYTIC VARIANT OF HYPEREOSINOPHILIC SYNDROME - The present invention is related to a gene set, a kit and a method for diagnosis of lymphocytic variant hypereosinophilic syndrome. | 11-15-2012 |
20120087958 | Multi-Dimensional Biomaterial and Method for Producing the Same - Biomaterial having a multi-dimensional structure and comprising differentiated MSCs tissue and demineralised bone matrix, wherein said demineralised bone matrix is dispersed within the differentiated MSCs tissue, method for producing the same and use thereof. | 04-12-2012 |
20110281105 | NANOSTRUCTURED ANTICORROSION COATING, STRUCTURE INCLUDING SAME AND METHOD FOR ANTICORROSION PROTECTION OF A SUBSTRATE - The invention relates to a polyelectrolyte-based nanostructured anticorrosion coating, comprising at least one main compartment which comprises:
| 11-17-2011 |
20100285192 | METHOD FOR FILTERING A LIQUID - The present invention is directed to a method for filtering a liquid, such as beer, comprising carrying out the filtration of said liquid in the presence of a filter aid, wherein said filter aid essentially comprises porous or non porous polyolefin particles having a specific mass less than 1000 kg/m3 and having an at least partly oxidized outer surface, whereby said outer surface is provided with nodular structures. | 11-11-2010 |
20100273671 | METHOD FOR THE DETERMINATION AND THE CLASSIFICATION OF RHEUMATIC CONDITIONS - Methods for the determination and the classification of a rheumatic condition in a synovial sample of a subject afflicted with a rheumatic condition are disclosed. Methods include the steps of determining in the level of expression of at least 20 genes or gene fragments in the synovial sample and identifying whether the level of expression of the genes in the sample correlates with the presence of a rheumatic condition. Kits are also described for the determination and the classification of rheumatic conditions which contain a low density microarray having probes suitable for hybridizing with at least 20 genes or gene fragments. On the basis of the hybridization results, the rheumatic condition is determined. | 10-28-2010 |
20100233226 | DRUG-ELUTING NANOWIRE ARRAY - The present invention relates to a nanowire array ( | 09-16-2010 |
20100209941 | METHOD, DEVICE AND KIT FOR DETERMINING CONDITIONS RELATED TO A DYSFUNCTION OF THE RENAL PROXIMAL TUBULE - A method, device and kit are disclosed for determining a condition related to dysfunction of the Renal Proximal Tubule (RPT) by detecting the presence of type III Carbonic Anhydrase, CAIII, in a urine sample of a subject. The method is used for diagnosis and to monitor the progress of a condition, and to determine the efficacy of a treatment. | 08-19-2010 |
20100185211 | HYBRID MANUAL-ROBOTIC SYSTEM FOR CONTROLLING THE POSITION OF AN INSTRUMENT - The present invention concerns hybrid manual-robotic system for supporting and moving a surgical instrument having active main structure ( | 07-22-2010 |
20100120891 | USE OF A GALECTIN-1-TARGETED RNAI-BASED APPROACH FOR THE TREATMENT OF CANCER - The present invention relates to an RNAi molecule suitable for reducing the expression of galectin-1 containing any of the sequences of SEQ ID NOs: 1-33, and preferably the sequences of SEQ ID NO: 2, 3, or 4, and to the use thereof as a medicament, or for the manufacture of a medicament for treating and/or for delaying the progression of cancer, preferably glioma, pancreatic cancer, head and neck cancer, melanoma, non-small-cell lung cancer and non-Hodgkin's lymphoma. The present invention also relates to compositions and methods for treating and for delaying the progression of cancer, preferably glioma, pancreatic cancer, head and neck cancer, melanoma, non-small-cell lung cancer and non-Hodgkin's lymphoma, for reducing the migration of tumor cells, preferably cells of glioma, pancreatic cancer, head and neck cancer, melanoma, non-small-cell lung cancer and non-Hodgkin's lymphoma, and/or for enhancing the efficacy of cancer therapies for the treatment of cancer, preferably glioma, pancreatic cancer, head and neck cancer, melanoma, non-small-cell lung cancer and non-Hodgkin's lymphoma, selected from the group comprising chemotherapy, radiation therapy, immunotherapy, and/or gene therapy. | 05-13-2010 |
20100080978 | POLYMER COMPOSITE MATERIAL STRUCTURES COMPRISING CARBON BASED CONDUCTIVE LOADS - The present invention provides a polymer composite material structure comprising at least one layer of a foamed polymer composite material comprising a foamed polymer matrix and 0.1 wt % to 6 wt % carbon based conductive loads, such as e.g. carbon nanotubes, dispersed in the foamed polymer matrix. The polymer composite material structure according to embodiments of the present invention shows good shielding and absorbing properties notwithstanding the low amount of carbon based conductive loads. The present invention furthermore provides a method for forming a polymer composite material structure comprising carbon based conductive loads. | 04-01-2010 |
20100035799 | METHOD FOR THE SYNTHESIS OF ANTHRACYCLINE-PEPTIDE CONJUGATES - The present invention relates to a method for the preparation of a compound of formula (I) or pharmaceutically acceptable salts thereof and intermediates thereof, comprising the steps of: | 02-11-2010 |
20100031452 | AZO DYES - The present invention relates to azo dyes, in particular azo dyes of Formula (I) or (II), a tautomer, a quaternary amine, or a salt thereof, | 02-11-2010 |
20090232849 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER - Compositions and a method for sensitizing a cancer for treatment by cytotoxic therapy is disclosed. The method includes the step of administering to the cancerous tissue or cells a pharmaceutical composition containing a | 09-17-2009 |
20090191573 | METHOD AND KIT FOR DETERMINING ANTIGEN CONTENT IN A SAMPLE USING DOUBLE IMMUNOHISTOCHEMICAL DETECTION - A method for determining antigen content in a region of interest of a sample is disclosed. The method includes a sequential immunomarking resulting in two chromogenic signals, which are respectively provided by a labile and a stabile chromogenic product. The method further involves acquisition, analysis and evaluation of digital images from such signals. A kit for determining antigen content in a region of interest of a sample is also described. | 07-30-2009 |
20090137494 | Tumor-activated prodrug compounds and treatment - The compound (W-Z-M) according to the invention comprises a component (M) chosen from the group consisting of markers and therapeutic agents possessing an intracellular active site (A.S.), linked to a ligand (W-Z) comprising an arm (Z) linked to a terminal group (W), characterized in that the linkage between the arm (Z) of the ligand (W-Z) and the component (M) prevents intracellular entry of the compound (W-Z-M) and/or inhibits expression of the marker (M), in that said linkage can be selectively cleaved by factors secreted by target cells so as to permit expression of the marker (M) or entry of the therapeutic agent (M) into said target cells, and in that the terminal group (W) provides for the stability of the compound (W-Z-M) in the serum and circulating blood. | 05-28-2009 |
20080311094 | Isolated Liver Stem Cells - Isolated liver progenitor stem cells and cell populations of isolated liver progenitor stem cells are disclosed. The progenitor stem cells originate from adult liver, especially human adult liver. The isolated progenitor stem cells have uses in medicine, hepatology, inborn errors of liver metabolism transplantation, infectious diseases and liver failure. Methods of isolating these cells and their culture is described. The isolated cells are characterized before and after differentiation. Their use for transplantation and as animal models of human disease, toxicology and pharmacology is disclosed. | 12-18-2008 |