UNIVERSITAT BERN Patent applications |
Patent application number | Title | Published |
20160128983 | CYTOTOXIC SUBSTANCE FOR USE IN COMBINATION WITH RADIOTHERAPY IN CANCER TREATMENT - The present invention provides a substance comprising a preparation of at least one chemotherapeutic or cytotoxic substance for the use in treatment of a disease of a mammalian patient, especially in the treatment of cancer. The invention suggests a symbiotic or synergistic combination of radiotherapy and chemotherapeutic or cytotoxic drug delivery. | 05-12-2016 |
20160015434 | Cap Device, Particularly for Closing A Burr Hole - The present invention relates to a cap device for closing a hole, particularly a burr hole, in a bone, particularly a skull, of a human or an animal, comprising a frame member for fastening the cap device to the bone, and a cap member for covering the hole. According to the invention, the cap member is integrally connected to the frame member, so that the cap member can be bent away from the frame member, particularly for allowing passage of a catheter through said hole. | 01-21-2016 |
20150265733 | BOMBESIN ANALOG PEPTIDE ANTAGONIST CONJUGATES - To provide a diagnostic and therapeutic medicament, a bombesin analog peptide antagonist conjugate is provided which has general Formula (I), wherein A is a metal chelator comprising at least one radionuclide metal, B is a spacer linked to N-terminal of C or a covalent bond and C is a bombesin analog peptide antagonist having a sequence as claimed, where further x is an Integer from 1 to 3 and n is an integer from 1 to 6. | 09-24-2015 |
20150251201 | ELECTROSPRAY DEVICE - The invention related to a device ( | 09-10-2015 |
20150141637 | TRICYCLIC NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM - The present invention provides novel tricyclic nucleosides and oligomeric compounds prepared therefrom. Incorporation of one or more of the tricyclic nucleosides into an oligomeric compound is expected to enhance one or more properties of the oligomeric compound. Such oligomeric compounds can also be included in double stranded compositions. In certain embodiments, the oligomeric compounds provided herein are expected to hybridize to a portion of a target RNA resulting in loss of normal function of the target RNA. | 05-21-2015 |
20150085979 | IMAGE DISTORTION CORRECTION AND ROBUST PHANTOM DETECTION - The invention relates to Method for detecting a phantom, comprising the steps of: arranging a phantom ( | 03-26-2015 |
20150037251 | MAMMALIAN HOMOLOGUES OF FLOWER, THEIR USE IN CANCER DIAGNOSTICS, PREVENTION AND TREATMENT - The invention relates inhibiting nucleic acids directed at mammalian homologues of the | 02-05-2015 |
20140100248 | Novel Heterocyclic Compounds as Modulators of Sphingolipid Signaling and Uses Thereof - The present invention relates to new heterocyclic compounds as modulators of sphingolipid signaling and uses thereof of as pharmaceutically active agents, suitable for treating proliferative, degenerative, infectious, and other diseases. | 04-10-2014 |
20130259851 | USE OF PROKARYOTIC SPHINGOSINE-1-PHOSPHATE LYASES AND OF SPHINGOSINE-1-PHOSPHATE LYASES LACKING A TRANSMEMBRANE DOMAIN FOR TREATING HYPERPROLIFERATIVE AND OTHER DISEASES - The present invention relates to the use of prokaryotic sphingosine-1-phosphate lyases (S1PL) and S1PLs that lack a transmembrane domain or of a nucleic acid encoding such an S1PL in the prevention or treatment of a disease condition associated with elevated levels of sphingosine-1-phosphate (S1P), and for which S1P elevation is directly or indirectly causative. In addition, the invention relates to a new product in the form of S1PL lacking the N-terminal loop domain. | 10-03-2013 |
20110111967 | METHOD FOR OPTIMIZED ISOLATION OF RNA FROM FIXED TISSUE - In invention relates to a method for the isolation of RNA from tissue pretreated with formaldehyde comprising homogenizing the sample in the presence of a guanidinium salt in aqueous solution, and incubating the sample in the presence of 0.1 M to 5 M ammonium salt at a temperature between 50° C. and 100° C. The heat treatment in the presence of an ammonium salts demodifies RNA by reverting methylol groups which are formed in the presence of formaldehyde between amino groups in nucleobases of RNA and in basic amino acids, and by cleavage of methylene bridges between amino groups in nucleobases of RNA and basic amino acids, to provide high RNA recoveries and consistently high quality of RNA for further reaction, e.g. for reverse transcriptase-polymerase chain reaction or microarray analysis. | 05-12-2011 |
20110020475 | CARDIOPLEGIC SOLUTION - The present invention relates to a new cardioplegic solution to arrest and protect the heart muscle during surgery. The cardioplegic solution according to the invention offers several significant advantages as compared to standard available solutions, and contains magnesium sulfate heptahydrate, potassium chloride, procaine hydrochloride and xylitol. | 01-27-2011 |
20100212666 | System for Controlling Administration of Anaesthesia - A system for controlling administration of a respiratory depressant drug or mixture of drugs to a spontaneously breathing patient comprises a drug delivery unit ( | 08-26-2010 |
20100008895 | NOVEL EXOENZYME TOXIN OF AEROMONAS SALMONICIDA, AND USES THEREFOR - A protein toxin named | 01-14-2010 |
20090062401 | DECALINE-DERIVED COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS - The present invention relates to compounds having a decaline scaffold, pharmaceutically acceptable salts of these compounds and pharmaceutical compositions containing at least one of these compounds together with pharmaceutically acceptable carrier, excipient and/or diluents. Said decaline-derived compounds can be used for prophylaxsis and/or treatment of diabetes mellitus type I, diabetes mellitus type II, tuberculosis and other infectious diseases, proliferative diseases, cancer, neurodegenerative diseases, obesity, cognitive dysfunctions and metabolic syndromes. | 03-05-2009 |
20090012540 | Implant for Sealing and/or Healing a Defect in an Annulus of an Intervertebral Disc - An implant for sealing and/or healing a defect in an annulus having an area intended to encompass the defect. The implant is a textile strip that has a middle area which is intended to encompass the defect and which is an oriented low-density embroidered structure for guided tissue ingrowth and reinforcement and end areas adjacent to the middle area which are a high-density embroidered structure. | 01-08-2009 |
20080213535 | Oriented Zeolite Material and Method for Producing the Same - An oriented zeolite material comprises a plurality of zeolite crystals ( | 09-04-2008 |