Siemens Healthcare Diagnostics Products GmbH Patent applications |
Patent application number | Title | Published |
20160077117 | INCUBATION DEVICE FOR AN AUTOMATIC ANALYSIS APPARATUS - An incubation device ( | 03-17-2016 |
20150219564 | METHOD FOR OPTICALLY DETERMINING AT LEAST ONE ANALYTE IN A SAMPLE - The present invention relates to a method for optically determining at least one analyte in a sample, in which a deviation from a reference value or the reference curve is evaluated as an indication that the optical determination of the at least one analyte is corrupted by measurement artifacts. | 08-06-2015 |
20150037797 | IMMUNOASSAY FOR DETECTION OF SPECIFIC NUCLEIC ACID SEQUENCES SUCH AS MIRNAS - The invention relates to a method of detecting nucleic acid molecules by immunoassay detection. Detection of a specific nucleic acid molecule of interest is achieved by using a nucleic acid probe in solution which hybridizes in solution to the nucleic acid molecule of interest. Immunoassay detection is achieved by using an antibody specific for the hybrid formed by hybridization of the nucleic acid probe to the nucleic acid molecule of interest. | 02-05-2015 |
20150014342 | Apparatus for separating spherical or cylindrical objects - An apparatus for separating rod-like or spherical agitating elements in an automatic analyzer allows quick and error-resistant separation and automated charging of cuvettes with the agitating elements. For this purpose, it comprises a lever provided with a bore, wherein the bore is configured such that it can accommodate one of the agitating elements. The bore, in a first position of the lever, is arranged beneath an entry opening and, in a second position of the lever, is arranged above an exit opening, wherein the lever, in the second position, closes the entry opening. | 01-15-2015 |
20140271405 | RETAINING DEVICE FOR A PIPETTING NEEDLE - The invention relates to a retaining device ( | 09-18-2014 |
20140199208 | CLOSURE DEVICE - The invention relates to a device ( | 07-17-2014 |
20140193300 | DEVICE FOR TRANSPORTING REACTION VESSELS - The invention relates to a rotatable device ( | 07-10-2014 |
20140192342 | METHOD AND SYSTEM FOR DETERMINING THE CONCENTRATION OF SUBSTANCES IN BODY FLUIDS - The invention relates to a method for the spectrophotometric determination of the concentration of multiple substances, preferably bilirubin, haemoglobin and lipids, in a sample of body fluid. | 07-10-2014 |
20140149778 | METHOD FOR TEMPORARY OPERATION OF AN AUTOMATED ANALYSIS DEVICE IN A STANDBY MODE - The present invention relates to an automated analysis device ( | 05-29-2014 |
20140147928 | METHOD FOR ASCERTAINING A TRANSMISSION VALUE - The invention is in the field of in vitro diagnostics and relates to a method for ascertaining a transmission value for a light signal that is pulsed at a frequency through a specimen in an automatic analysis appliance. It also relates to a transmission measurement apparatus for an automatic analysis appliance, comprising a light source that is pulsed at a frequency and a photodetector having a downstream A/D converter. | 05-29-2014 |
20140141518 | REAGENT STATION FOR AN AUTOMATED ANALYSIS DEVICE - The invention relates to a reagent station ( | 05-22-2014 |
20140083565 | Hollow needle for a sample pipettor - The invention relates to a hollow needle ( | 03-27-2014 |
20140080144 | METHOD FOR DETERMINING PLATELET-ASSOCIATED ANALYTES - The present invention relates to a routine in vitro method for determining platelet-associated analytes, for example VWF, factor XIII, fibrinogen or D-dimer, in a sample of platelet-rich plasma. | 03-20-2014 |
20140065017 | Adjustment system for a transfer system in an in-vitro diagnostics system - The invention relates to an adjustment system ( | 03-06-2014 |
20140050619 | Reaction Vessel - A reaction vessel ( | 02-20-2014 |
20130224883 | Method for recognizing interferences in in vitro diagnostic assays - The present invention is in the field of in vitro diagnostics and relates to a method for recognizing interfering disruptive factors, such as heterophile antibodies or rheumatoid factors for example, in a sample. | 08-29-2013 |
20130224777 | Screening method for finding samples having antiphospholipid antibodies - The present invention is in the field of coagulation diagnostics and relates to a screening process for finding samples containing antiphospholipid antibodies (lupus anticoagulants), wherein the platelet aggregation-stimulating action of said antiphospholipid antibodies is determined in vitro. | 08-29-2013 |
20130195718 | Method for Heating a Volume of Liquid in a Heated Pipetting Needle - The invention relates to a pipetting device for automatic analysis instruments and a method for heating a volume of liquid in a heated pipetting needle. | 08-01-2013 |
20130137115 | HOMOGENEOUS DETECTION METHOD - The invention relates to methods for the quantitative or qualitative detection of an analyte in an assay and adequate reagents therefor, particularly a homogeneous binding test. According to the invention, an analyte-specific binding partner R1 comprises more than one specific binding point for a specific binding partner X that is associated with a component of a signal-forming system while a second analyte-specific binding partner R2 comprises more than one specific binding point for a specific binding partner Y which is also associated with a component of a signal-forming system. | 05-30-2013 |
20130008236 | METHOD FOR STANDARDIZING MEASURED RESULTS IN A SYSTEM FOR MEASURING THROMBOCYTE FUNCTION - The invention is in the field of coagulation diagnostics and relates to in vitro methods for determining thrombocyte function using measuring cells, particularly measuring cells of the PFA system. The methods make it possible to obtain standardized measured results which are comparable, irrespective of the type of measuring cell used. | 01-10-2013 |
20130004487 | SCD40L AND PLACENTAL GROWTH FACTOR (PIGF) AS BIOCHEMICAL MARKER COMBINATIONS IN CARDIOVASCULAR DISEASES - The invention relates to novel markers of vascular inflammation and combinations thereof as diagnostic and prognostic tools in patients with cardiovascular diseases. The markers also act as tools that facilitate the selection of active ingredients for the treatment of such diseases, and finally act as starting points for the treatment of cardiovascular diseases. Furthermore, the invention relates to the creation of an individual risk profile of negative events that are associated with the progression of arteriosclerosis. | 01-03-2013 |
20120295291 | Method for Determining the Risk of Clopidogrel Resistance - The present invention relates to a method for identifying patients for whom there is a high probability of their not benefiting from therapy with clopidogrel. It was found that the thrombocyte activity of a patient makes it possible to establish, even before the intake of clopidogrel, whether the patient has an increased risk of clopidogrel resistance (high on-treatment platelet reactivity). | 11-22-2012 |
20120252044 | Controls and kit for thrombocyte activity tests - The present invention is in the field of coagulation diagnostics and relates to a kit and method for preparing controls for use in test methods for determining thrombocyte function. | 10-04-2012 |
20120237960 | Devices and Methods for Determining the Platelet Function in a Centrifugal Analyzer - The invention lies in the field of platelet function diagnostics and relates to devices and methods for determining the platelet function in a centrifugal analyzer. | 09-20-2012 |
20120202232 | Heparin-insensitive Method for Determining Direct Coagulation Factor Inhibitors - The invention is in the field of coagulation diagnostics and relates to a heparin-insensitive method for determining direct coagulation factor inhibitors in a sample, in particular direct thrombin and factor Xa inhibitors. | 08-09-2012 |
20120190053 | Method of determining factor XIII with the aid of plasma-based reference material - The present invention is in the field of in-vitro diagnostics and relates to a method of determining the blood-clotting factor XIII (factor XIII, F XIII) with the aid of plasma-based reference material, and a test kit for carrying out the method. | 07-26-2012 |
20120190052 | Method of determining factor XIII by means of NAD(P)H-analogues - The invention is in the field of in-vitro diagnostics and relates to a photometric method for determining the blood-clotting factor XIII (factor XIII, F XIII) with the aid of NAD(P)H analogues, and a test kit for carrying out the method. The invention is in the field of in-vitro diagnostics and relates to a photometric method for determining the blood-clotting factor XIII (factor XIII, F XIII) with the aid of NAD(P)H analogues, and a test kit for carrying out the method. | 07-26-2012 |
20120171697 | Method of Determining Inhibitors of Coagulation - A homogeneous method of determining inhibitors of proteolytically active coagulation factors (anticoagulants) in a sample, in particular direct thrombin and factor Xa inhibitors, and also a test kit to be used in such a method. Use is made of ligands which bind to the proteolytically active coagulation factor but are not cleaved by the latter and compete with the anticoagulant to be determined. | 07-05-2012 |
20120156708 | Method For Simultaneously Determining Multiple Coagulation Proteases - The present invention relates to a chromogenic method for simultaneously determining the activity of multiple coagulation proteases or for simultaneously determining the inhibition of multiple coagulation proteases in a single test reaction. For this purpose, use is made of two chromogenic substrates which have different absorption maxima and whose color signals can be separated spectrally. | 06-21-2012 |
20120072027 | METHOD AND APPARATUS FOR LOW-VOLUME ANALYZER WITH FIXED AND VARIABLE INDEXING - A sample analyzer with fixed and variable indexing that is structured and arranged to align reaction vessels, e.g., cuvettes, at a pre-determined, fixed point while maintaining a positional sequence using variable indexing. Variable indexing allows cuvettes to be presented to multiple, fixed point resources at multiple occasions in a systematic progression in a highly efficient manner. The presentation of cuvettes to multiple, fixed point resources at multiple times is superior to existing indexing. | 03-22-2012 |
20110314907 | CONTACTLESS FILLING LEVEL MEASUREMENT OF LIQUIDS - The invention relates to a device and a method for the contactless capacitive filling level measurement of a filling medium in a container, the device having a plurality of measurement electrodes and at least one reference electrode. | 12-29-2011 |
20110229414 | Contrast Agents For Detecting Protease Activity By Means Of Hyperpolarization And For Stratifying Patients - A contrast agent is disclosed for imaging methods. In at least one embodiment the contrast agent includes a construct including i) at least two copies of a substrate for at least one tumor-specific protease, and ii) at least one linker having at least one recognition site for at least one tumor-specific protease, wherein a hyperpolarization site is located at the N and/or C terminus of the substrate, and wherein the linker is configured such that the hydrophobic ends of the substrate interact and form a central core by means of noncovalent interactions with the lipophilic residues, and the contrast agent together with a parahydrogen metal template for use in an imaging method for diagnosing a tumor. At least one embodiment of the invention further relates to a method for imaging a tumor tissue, wherein the above-described contrast agent accumulated in a tumor tissue is imaged using a suitable imaging method after hyperpolarization by way of contact with a parahydrogen metal template, and also to a method for imaging a tumor tissue in a patient, wherein a) a contrast agent as described above is administered to a patient, b) a parahydrogen metal template is administered to the patient, and c) the presence of a tumor is depicted using an imaging method. | 09-22-2011 |
20110150758 | TRACKING OF BONE MARROW CELLS FOR METASTASIS SCREENING - At least one embodiment of the invention relates to bone marrow precursor cells or bone marrow cells of a patient, the cells labeled with at least one contrast agent suitable for an imaging method, for use in an imaging method for diagnosing a metastasizing cancer, wherein the local accumulation of the labeled precursor cells or bone marrow cells indicates the presence of a metastasizing tumor growth. At least one embodiment also relates to a method for imaging a metastasizing tumor tissue in a patient, wherein a) bone marrow precursor cells or bone marrow cells are extracted from a patient, b) these precursor cells or bone marrow cells are labeled with at least one contrast agent suitable for an imaging method, c) the precursor cells or bone marrow cells thus labeled are retransplanted or reinjected into the patient, and d) the presence of metastasizing tumor cells is depicted with an imaging method. At least one embodiment also relates a method for imaging a metastasizing tumor tissue, wherein a suitable imaging method is used to image bone marrow precursor cells and/or bone marrow cells that are accumulated in a metastasizing tumor tissue and labeled with at least one contrast agent suitable for an imaging method. | 06-23-2011 |
20110124001 | Compositions For Use In Detection Of Multiple Analytes - Methods, compositions and kits are disclosed. The methods are directed to determining the presence or relative amounts of two or more components in a medium. A combination is provided comprising a medium suspected of containing the components, at least two sensitizer reagents and at least one reactive reagent activatable by singlet oxygen. The sensitizer reagents are capable of generating singlet oxygen and are distinguishable by wavelength of sensitization. The combination of sensitizer reagents and reactive reagents allows differential detection of the components. The sensitizer reagents are differentially activated. The amount of signal generated as a result of the activation of said reactive reagent is determined wherein the amount thereof is related to the amount of each of the components in the medium. | 05-26-2011 |
20100086953 | Blood Coagulation Assays - The invention relates to methods for determining the activity of a proteolytic coagulation factor of the blood coagulation cascade in a body fluid such as whole blood or plasma. A combination is provided in a reaction mixture. The combination comprises the sample and an activation agent for activating a proteolytic coagulation factor of the blood coagulation cascade or for activating the blood coagulation cascade. The effect of the activating on a reagent system comprising a cleavable moiety is evaluated. The cleavable moiety is or becomes bound to a chemiluminescent agent or a sensitizer agent or both. The chemiluminescent agent and the sensitizer agent are related in that, when in close proximity, energization of the sensitizer agent results in energization of the chemiluminescent agent. The effect of the activating is related to the activity of a proteolytic coagulation factor of the blood coagulation cascade wherein the effect is the extent of cleavage of the cleavable moiety. | 04-08-2010 |