ROCHE DIAGNOSTICS OPERATIONS, INC. Patent applications |
Patent application number | Title | Published |
20160061831 | AUTOMATIC ANALYSIS DEVICE - An analyzing device of the present invention is provided with a flow chamber that a fluid including magnetic particles associated with a labeling substance flows from a fluid inlet to a fluid outlet, magnetic trap means to apply a magnetic field for trapping the magnetic particles to the fluid in the flow chamber, a working electrode and a counter electrode to apply a voltage to the magnetic particles trapped by the magnetic trap means, and to emit a luminescence, a light detection element to detect a luminescence derived from the labeling substance on the magnetic particles trapped in the flow chamber, and regulating means to regulate a region that the light detection element detects the luminescence derived from the labeling substance on a part of magnetic particles of them trapped by the magnetic trap means. | 03-03-2016 |
20160047771 | BLOOD GLUCOSE METER WITH LOW COST USER INTERFACE HAVING PROGRAMMED GRAPHIC INDICATORS - A blood glucose meter with a low cost user interface has a color glucose scale that is indexed by indicators programmed according to the user's blood glucose target range through a separating computing device due to the limited meter user interface. The color glucose scale is static and placed adjacent to the indicator such as by being molded into the housing, printed on the housing, or attached to the display. The low cost user interface has a monochrome segmented display with certain segments serving as a plurality of indicators. An indicator scaling module uses the target blood glucose range of the person with diabetes to calculate the blood glucose ranges for each indictor to index the color glucose measurement scale. The indicator scaling module can also assign attributes to the indicator such as flashing. The graphic representation of the user's blood glucose measurement aids in user interpretation. | 02-18-2016 |
20150338288 | Handheld Analyte Meter With Recharging Control For Improved Analyte Testing - A handheld analyte meter, such as a blood glucose meter, has a measurement module, a rechargeable battery and a charging control to select a maximum charging current to regulate self-heating during recharging that can interfere with analyte tests. Self-heating by the meter can bias temperature measurements made inside the meter that are used to determine whether the temperature is acceptable for testing. Prior to beginning a charging session, the charging control selects the maximum charging current that does not change during the charging session based capacity of a charging source along with a first temperature measured near the battery that is compared with a first temperature range. By selecting the maximum charging current in this manner, the risk of the measurement module preventing a test under high lock-out conditions and the risk of the measurement module allowing a test when low lock-out conditions that are masked is reduced. | 11-26-2015 |
20150324520 | Blood Glucose Meter Supporting Contextual Data Filtering - The handheld blood glucose meter creates blood glucose records having contextual information to improve filtering of blood glucose records for improved healthcare decisions. The contextual information includes events and associated sub-events. The user selects an event indicator from the plurality of event indicators, and the meter associates the blood glucose measurement with an event that corresponds to the event indicator. The user selects a sub-event indicator from the plurality of sub-event indicators, and the meter associates the blood glucose measurement with a sub-event that corresponds to the sub-event indicator. The user repeats the preceding steps to obtain a plurality of blood glucose measurements with associated events and sub-events. The user selects data filtering, a predetermined range of blood glucose measurements along with an event and sub-event to produce a filter result meeting these criteria. | 11-12-2015 |
20150273147 | SYSTEM AND METHOD FOR ADJUSTING THERAPY BASED ON RISK ASSOCIATED WITH A GLUCOSE STATE - The present disclosure relates to a system and method for determining a basal rate adjustment based on risk associated with a glucose state of a person with diabetes. A method may include detecting a glucose state of the person based on a received glucose measurement signal and determining a current risk metric associated with the detected glucose state. The method may include identifying a reference glucose state and a reference risk metric associated with the reference glucose state, and calculating an adjustment to a basal rate of a therapy delivery device based on the current risk metric associated with the detected glucose state and the reference risk metric associated with the reference glucose level. | 10-01-2015 |
20150241268 | MEASURING MODULE FOR REMISSION PHOTOMETRIC ANALYSIS AND METHOD FOR THE PRODUCTION THEREOF - A measuring module for remission photometric analysis of one or a plurality of specimens is provided with the following features: a transmitter with a transmission channel for transmitting a measuring radiation to location of the specimen; a first focusing device for focusing the measuring radiation on the specimen; a receiver with a receiving channel to receive the radiation reflected by the specimen; a second focusing device made of plastic for focusing the measuring radiation reflected by the specimen onto the receiver, whereby the second focusing device further comprises a filter which is designed to filter a fluorescence radiation from the specimen excited by the measuring radiation. | 08-27-2015 |
20150224497 | SAMPLE COLLECTION TUBES - A sample collection tube is disclosed for collecting a body fluid sample. The tube includes a closure arranged at an open end to close the open end and a partially evacuated inner space. The closure also includes a base portion connected to the sidewall and a cap portion coupled to the base portion, where the cap portion has an elastomeric material that is pierceable from outside of the tube for collecting a sample into the partially evacuated inner space and where the cap portion can be pivotable with respect to the sidewall such as to make the inner space accessible for withdrawing an aliquot of the sample. Alternatively, the cap portion can be separable from the base portion to make the inner space accessible and the base portion can include a self-resealable valve adapted to allow access of a pipetting unit into the inner space when the cap portion is separated and adapted to re-seal after withdrawal of the pipetting unit. Also disclosed is a work cell for handling sample collection tubes. | 08-13-2015 |
20150196258 | LOW ENERGY WIRELESS COMMUNICATION SYSTEMS AND METHODS FOR MEDICAL DEVICES - A method performed by a medical device for transmitting data packets includes: removing select data fields from a data packet defined in accordance with IEEE standard 11073 to form a modified data packet; determining a length of the modified data packet; determining whether the length of the modified data packet is greater than a predetermined maximum length of data packets under the Bluetooth low energy protocol, as defined in Bluetooth Core Specification version 4.0 or higher; when the length of the modified data packet is greater than the predetermined maximum length of data packets defined under the Bluetooth low energy protocol, partitioning the modified data packet into a plurality of individual data packets, wherein each of the individual data packets includes a portion of the modified data packet; and transmitting the individual data packets via an antenna in accordance with the Bluetooth low energy protocol. | 07-16-2015 |
20150150494 | DEVICE FOR PERFORMING AT LEAST ONE MEDICAL FUNCTION - A device for performing at least one medical function on a user is proposed. The device has at least one medical functional element that is designed to perform the medical function. The medical function is selected from a diagnostic, a therapeutic and a surgical function. The device has at least one evaluation and control part that comprises at least one actuation component for controlling the medical function. The evaluation and control part has at least one casing and at least one battery receptacle. The battery receptacle comprises at least one electrical energy reservoir, more particularly at least one battery. The battery receptacle is designed to be opened irreversibly by the user for removing the energy reservoir. | 06-04-2015 |
20150141870 | Method for Producing a Membrane Ring or Test Strip Ring and Ring Magazine - A method for producing a membrane ring or test strip ring for a diagnostic test device includes an elongate strip that is divided into segments by cuts running transversely to the longitudinal direction of the strip, where the cuts are made only as far as a residual width of the strip so that a material bridge remains intact between the segments adjacent to the cuts ( | 05-21-2015 |
20150118759 | SYSTEM AND METHOD FOR DISPLAY TYPE DETECTION OF A HANDHELD MEDICAL DEVICE - A device which supports identification of an integrated display and dynamic adjustments to operating parameters thereof includes: a port that receive a test strip having a reaction site for receiving a sample of fluid from a patient, a blood glucose (bG) meter cooperatively operable with a test strip inserted in the port to measure glucose in a sample of fluid on the test strip, and a display device having an electrically resistive component integrated therein and operable to display the glucose measurement in accordance with one or more operating parameters associated with the display device The system also includes a monitoring module electrically connected to the resistive component, wherein the monitoring module determines a type for the display device based on a resistance of the resistive component and a control module that selectively adjusts a given operating parameter of the display device in accordance with the type of display device. | 04-30-2015 |
20150118534 | BATTERY WELL FOR A MEDICAL TESTING DEVICE - An electronic device may include a battery well and a plurality of tabs. The battery well may receive a disk-shaped battery and may include an annular sidewall, an open end, an end wall and a recess. The open end may be disposed at a first end of the sidewall. The end wall may be substantially perpendicular to the sidewall at a second end of the sidewall and axially between the recess and the open end. The recess may be disposed at the second end of the sidewall and adjacent the end wall. The recess may be adapted to receive a portion of the battery therein. The tabs may be disposed at the open end and may extend radially inward from the sidewall to releasably retain the battery in the battery well. The tabs may define a plane that is substantially parallel to the end wall. | 04-30-2015 |
20150096888 | bG METER LENS ATTACHMENT AND SEAL - A blood glucose test device with viewing lens seal includes a meter body rigid portion of a first polymeric material and an opening. A resilient portion of a second polymeric material more compressible than the first polymeric material integrally connected to the rigid portion defines a rigid portion outer covering. A resilient portion edge extends beyond the rigid portion and partially into the opening about a perimeter of the opening. A transparent polymeric material lens has an outer perimeter surface in contact with the resilient portion edge. Multiple flexible arms extending from the lens each have a hook member. Each hook member engages a receiving member positioned in a meter body and is retained by multiple backup ribs. Hook member engagement at a locking position pulls the lens toward the edge partially compressing the second polymeric material and creating a fluid seal between the perimeter surface and edge. | 04-09-2015 |
20150095042 | HIGH/LOW BLOOD GLUCOSE RISK ASSESSMENT SYSTEMS AND METHODS - A blood glucose (bG) measurement engine selectively measures bG levels in blood samples input to a handheld diabetes management device. A computer readable medium includes code executed by a processor to: identify a period of N days, the period including the current date and N−1 days immediately prior to the current date, wherein N is an integer greater than 6; determine a total number of the N days during which the patient input at least two blood samples; and, when the total number of the N days is greater than M, M being an integer greater than zero and less than or equal to N: calculate a value based on the bG levels of blood samples input during the period; based on the value, classify the patient as having a first, second, or third risk of being hypoglycemic in the future. | 04-02-2015 |
20150079689 | DISPLAYING GLUCOSE MEASUREMENTS ON A HANDHELD GLUCOSE METER - A computer-implemented method is provided for displaying glucose measurements of a person on a handheld glucose meter. The method includes: determining a current blood glucose measurement for a person from a test strip inserted into a port of the handheld glucose meter; displaying the current glucose measurement on a result screen of the handheld glucose meter immediately following the measurement of the current glucose measurement by the handheld glucose meter; providing an indicium of a logbook screen on the result screen concurrently with the display of the current glucose measurement on the result screen; and displaying the logbook screen in response to a user input received by the handheld glucose meter, where the logbook screen displays the current glucose measurement along with at least two preceding glucose measurements of the person. | 03-19-2015 |
20150066382 | METHOD AND ANALYSIS SYSTEM FOR PROCESSING BIOLOGICAL SAMPLES - A method for guiding user input on a computer system of an analysis system that includes an in vitro diagnostic, IVD, device. The IVD device is coupled to the computer system that includes a display, processor, and memory to store applications being executable on the processor. A first application includes instructions that generate on the display a first graphical user interface that includes a set of user interface elements. Each user interface element is positioned in a defined region within the first graphical user interface. The first application includes instructions that control the IVD device to perform an IVD task that includes a sequence of IVD actions. The user activation of the IVD action is performed using a corresponding user interface element. The memory includes geometry data describing a display position for each interface element. | 03-05-2015 |
20150061890 | PRESENTING DATA GENERATED BY A CONTINUOUS GLUCOSE MONITOR - A computer implemented method for transmitting messages generated by a continuous glucose monitor (CGM), the method comprising: generating a first message at the CGM at a first time, the first message being related to blood glucose measuring; generating a second message at the CGM at a second time, the second time being after the first time, the second message being related to blood glucose measuring; determining an elapsed time since a transmitter of the CGM has transmitted data; determining whether the elapsed time is greater than a threshold; determining whether the second message is to be transmitted before the first message, in response to the elapsed time being greater than the threshold; and transmitting data corresponding with the second message before transmitting data corresponding with the first message to a diabetes management device, in response to determining that the second message is to be transmitted before the first message. | 03-05-2015 |
20150057616 | Hand-Held Injection Devices and Methods of Use - At least one hand-held injection device for the metered injection of a liquid drug into a person's tissue is disclosed. The exemplary injection device comprises an elongated drug reservoir having a longitudinal reservoir axis (A), an elongated dosing unit having a dosing unit inlet, a dosing unit outlet, and a metering cavity, the dosing unit having a longitudinal dosing unit axis (A′), the elongated drug reservoir being fluidically coupled to the dosing unit inlet. The dosing unit and the drug reservoir are arranged such that the longitudinal dosing unit axis (A′) is in parallel alignment with the reservoir axis (A). The dosing unit structured to allow the flow of the liquid drug from the drug reservoir into the metering cavity via the dosing unit inlet, thus charging the metering cavity, and to subsequently discharge the metering cavity by dosing drug out of the metering cavity into the dosing unit outlet. | 02-26-2015 |
20150038814 | AMPEROMETRIC SENSOR AND METHOD FOR ITS MANUFACTURING - An in vivo amperometric sensor is provided for measuring the concentration of an analyte in a body fluid. The sensor comprises a counter electrode and a working electrode, and the working electrode comprises a sensing layer which is generally water permeable and arranged on a support member adjacent to a contact pad. The sensing layer comprises an immobilized enzyme capable of acting catalytically in the presence of the analyte to cause an electrical signal. The sensing layer has an upper surface facing the body fluid and a lower surface facing away from the body fluid, and the immobilized enzyme is distributed within the sensing layer in such a way that the enzyme concentration in the middle between the upper and lower surfaces is at least as high as on the upper surface of the sensing layer. | 02-05-2015 |
20150016937 | TRANSPORT DEVICE - A device is presented in which individual sample containers can be conveyed from a start position to a target position. The role of start position and target position is interchangeable. The movement of a gripper is a combined lifting movement and translation movement. With the aid of a simple drive, the gripper is moved along a movement path that is mechanically defined. | 01-15-2015 |
20140365534 | Management method and system for implementation, execution, data collection, and data analysis of a structured collection procedure which runs on a collection device - Methods for performing a structured collection procedure by utilizing a collection device are disclosed herein, in which a collection procedure is initiated for performing one or more data collections for one or more data event instances occurring according to a schedule of events. Each data event instances comprises a data collection pertaining to a biomarker to be performed according to one or more conditions of an adherence criterion. Each data event instance is determined to be successful or unsuccessful on the basis of actual performance of the data collection and meeting certain conditions of the predetermined adherence criteria for the data event instance. Contextual information for successful data collections is generated and a data file generated for storing records relating to successful data collections. For unsuccessful data event instances, substitute data relating to data collections performed separately from the collection procedure are included in the data file records for the collection procedure if the substitute data is determined to meet conditions of the predetermined adherence criterion for the corresponding data event instance. | 12-11-2014 |
20140363259 | APPARATUS AND METHOD FOR HANDLING SAMPLE TUBES AND LABORATORY SYSTEM - An apparatus for handling sample tubes is presented. The apparatus comprises a sample tube tray, a sample tube individualizer, a first conveyor, a second conveyor, a sample tube buffer, and a sample tube rack inserter. The sample tube tray stores sample tubes in bulk commodity. | 12-11-2014 |
20140360269 | ACCELERATION SENSITIVE INDICATOR - An acceleration sensitive indicator for indicating a centrifugation status of a biological sample, a sample container comprising the indicator, a centrifuge for centrifuging samples and an analytical system for analyzing centrifuged samples are disclosed. The indicator comprises at least one closed chamber, formed between two opposite surfaces, that comprises an indication zone that comprises at least two fluid transfer zones or at least one particle transfer zone. The at least one fluid transfer zone comprises a solid carrier phase and a fluid stabilized in the solid carrier phase or at least one non-stabilized non-Newtonian fluid having thixotropic and/or shear thinning properties. The at least one particle transfer zone comprises a particle stabilizing fluid comprising stabilized dispersed particles. The fluid or particles have a distribution with respect to the indication zone changeable upon application of a g-force above a threshold value, the change of distribution indicating the centrifugation status. | 12-11-2014 |
20140342465 | LABORATORY AUTOMATED SYSTEM WITH COMMON SAMPLE BUFFER MODULE - A new laboratory automated system comprising a plurality of work cells coupled to a conveyor and a method for processing sample tubes are disclosed, both of which enable a system to maintain the maximum overall throughput regardless of the number and throughput of the individual work cells and regardless of the frequency at which sample tubes are loaded into the system. This is achieved by a sample buffer module coupled to the conveyor, the sample buffer module being in common to the plurality of work cells, and by a sample workflow manager configured to dispatch sample tubes from the sample buffer module to the work cells via the conveyor with a frequency for each work cell, which is equal to the sample processing throughput of each respective work cell. | 11-20-2014 |
20140325065 | MOBILE PHONE APPLICATION FOR DIABETES CARE WITH MEDICAL FEATURE ACTIVATION - A method for activating a physician-prescribable feature of an application program executed on a mobile device is disclosed. The method includes receiving, by the application program, an activation code to activate a feature of the application program and one or more parameters associated with a prescription. The method includes transmitting, by the application program, the activation code to a server and receiving an authorization code from the server, where the authorization code indicates a validity of the activation code. The method includes activating, by the application program, the feature using the activation code, the activation being performed in response to the activation code being valid; configuring, by the application program, the activated feature using at least one of the one or more parameters associated with the prescription; and generating, using the activated feature, data based on the one or more parameters associated with the prescription. | 10-30-2014 |
20140324800 | Management Method And System Implementation, Execution, Data Collection, And Data Analysis Of A Structured Collection Procedure Which Runs On A Collection Device - Embodiments related to a system and method managing the implementation, execution, data collection, and data analysis of a structured collection procedure running on a portable, hand-held collection device are disclosed. The collection device performing the structured collection procedure has program instructions that when executed by a processor causes the processor to initiate automatically a schedule of events of the structured collection procedure upon one or more entry criterions being met at some unknown time, store in memory patient data collected in accordance to the schedule of events, end automatically the structured collection procedure upon one or more exit criterions being met at some unknown time, and mark/indicate the structured collection procedure as completed if no exception occurred during performance of an event in the schedule of events. | 10-30-2014 |
20140324465 | METHOD FOR RECONCILING MEDICAL DATA CAPTURED ON ONE DEVICE WITH A STRUCTURED TEST ADMINISTERED ON ANOTHER DEVICE - A method for analyzing diabetes related information by a diabetes management application residing on a computing device. The method may include: receiving a data entry over a communication link from a blood glucose meter, where the data entry includes a glucose measurement and an indicator of a pre-established activity associated with the glucose measurement; evaluating the data entry in relation to a subject structured test based in part by comparing the indicator from the data entry with collection events associated with the subject structured test; identifying the data entry as compatible with the subject structured test when the data entry correlates with a given collection event specified by the subject structured test; identifying the data entry as non-compatible with the subject structured test when the data entry does not correlate with the given collection event specified by the subject structured test; and inputting the data entry into a logbook. | 10-30-2014 |
20140324464 | SYSTEM PORTAL CONTROL FOR A DIABETES MANAGEMENT SYSTEM - A computer-implemented method for managing accounts in a diabetes management system. The method includes receiving, by an account manager, a request to deactivate a first account associated with a healthcare provider. The first account may be associated with a plurality of patient accounts. The account manager may be implemented as computer executable instructions executing on a computer processor of a server device. The method includes removing, by the account manager, access to data associated with the first account. Each of the patient accounts associated with the first account are identified and may be deactivated by the account manager. An electronic notification may be sent to a person associated with each of the identified patient accounts, advising the person that the corresponding patient account has been deactivated. An audit record may be created in a data store, the audit record indicating the deactivation of the first account. | 10-30-2014 |
20140324463 | WEB ACCOUNT CREATION AND MANAGEMENT, DATA SHARING, HOME PAGE SETTING, AND DATA REPORTING - A method includes: receiving, at a computing device, diabetes management data from a diabetes management device, wherein the diabetes management data does not include a blood glucose (bG) measurement; using the computing device, transmitting an indicator of an account and the diabetes management data to a diabetes management server. The method further includes, using the diabetes management server: creating a bG measurement entry for the account in a database, leaving empty a field of the bG measurement entry for a bG measurement in the bG measurement entry based on the diabetes management data not including a bG measurement; and storing the diabetes management data in one or more respective fields of the bG measurement entry. The method further includes, using the diabetes management server, generating a user interface for displaying data stored in the bG measurement entry and at least one other bG measurement entry associated with the account. | 10-30-2014 |
20140324462 | MEDICAL DATA TRANSFER COMPONENT - Diabetes care management system and method for transferring medical data from a handheld medical recording device to a host computer via a data transfer component. The steps of the data transfer component comprising detecting a data upload request and detecting a medical device ready to communicate, verifying a unique ID, receiving patient medical data, including an authentication token with patient medical data, and sending patient medical data along with the authentication token for association with a user account. | 10-30-2014 |
20140324461 | DIABETES MANAGEMENT SYSTEM WITH CONTEXTUAL DRILL DOWN REPORTS - A method for displaying contextual information by a diabetes reporter of a diabetes management system is provided. The method may include: displaying a graphical representation of a plurality of data values over a period of time in a first area of an interface display; receiving a selection of a desired data value from among the plurality of data values displayed in the first area; displaying, in response to the selection, a first set of data entries and a second set of data entries in a second area of the interface display concurrently with the graphical representation of the plurality of data values in the first area of an interface display. The first set of data entries and the second set of data entries are displayed in chronological order within a preset time period. | 10-30-2014 |
20140322815 | PAIRING AND SYNCHRONIZING A MOBILE PHONE APPLICATION WITH A HANDHELD GLUCOSE METER - A diabetes management system includes a handheld medical device, a mobile computing device, and a diabetes management application. The handheld medical device is configured to determine, in response to a port receiving a test strip, whether an auto-send feature is enabled on the handheld medical device, determine whether the handheld medical device is paired with a mobile computing device, and selectively instruct a wireless transceiver to establish a wireless connection and communicate a glucose measurement and identifying information to the mobile computing device. The mobile computing device is configured to execute the diabetes management application. The diabetes management application is configured to process a plurality of glucose measurements and identifying information associated with each of a plurality of glucose measurements. | 10-30-2014 |
20140318991 | System and method for quality assurance of a biosensor test strip - The present invention provides a test strip for measuring a signal of interest in a biological fluid when the test strip is mated to an appropriate test meter, wherein the test strip and the test meter include structures to verify the integrity of the test strip traces, to measure the parasitic resistance of the test strip traces, and to provide compensation in the voltage applied to the test strip to account for parasitic resistive losses in the test strip traces. | 10-30-2014 |
20140289875 | METHOD AND SYSTEM FOR ENSURING SENSITIVE DATA ARE NOT ACCESSIBLE - A method and an analysis system that help ensure that sensitive data, including in particular patient data, are not accessible to unauthorized persons is presented. The method and system help prevent sensitive data stored on portable devices from being transported along with a portable device to a location outside of a security perimeter. By determining if a portable device is outside of the security perimeter and then automatically erasing the sensitive data stored on the portable device if that is the case, the method and system help prevent disclosure of sensitive data to unauthorized persons. | 09-25-2014 |
20140280690 | MEDICAL DEVICE AND EXTERNAL DEVICE COORDINATION SYSTEMS AND METHODS - A method includes: confirming a wireless communication link between a medical device and a mobile computing device hosting an application; requesting identifying data for the medical device via the wireless communication link; and receiving identifying data for the medical device via the wireless communication link in response to the request. The method further includes: presenting an option to register the medical device on a display of the mobile computing device; receiving an affirmative indication to register the medical device; requesting input of patient identifiable data for a user of the medical device in response to receiving the affirmative indication to register; receiving patient identifiable data for the user of the medical device in response to the request for input; forming registration data from the patient identifiable data and the identifying data; and registering the medical device with a manufacturer of the medical device using the registration data. | 09-18-2014 |
20140278124 | System and Methods for Analyzing Blood Glucose Data and Quantifying the Success or Failure of Insulin Therapy - A system and technique are enclosed for determining the effectiveness of a blood glucose therapy treatment. Examples of this technique include analyzing sufficiency of blood glucose data collected from a patient with a computing device, analyzing hypoglycemic risk based on the blood glucose data with the computing device, analyzing glycemic control for the blood glucose data with the computing device, analyzing glycemic variability of the blood glucose data with the computing device, and outputting results from said analyzing the sufficiency, said analyzing the hypoglycemic risk, said analyzing the glycemic control, and said analyzing the glycemic variability with the computing device. | 09-18-2014 |
20140278123 | Method for the Detection and Handling of Hypoglycemia - A method is described herein to detect and treat hypoglycemia. An example of this method involves the detection of hypoglycemia in a patient with a computing device, computation of a recommended carbohydrate amount to ingest by the patient with the computing device in response to said detecting the hypoglycemia, output of the recommended carbohydrate amount with the computing device, and the performance of a hypoglycemia surveillance with the computing device to determine whether the recommended carbohydrate amount remedied the hypoglycemia. | 09-18-2014 |
20140274793 | NT-proANP AND NT-proBNP FOR THE DIAGNOSIS OF STROKE - The present invention relates to a method for diagnosing a transitory ischemic attack (TIA) in a subject who is suspected to have exhibited a transitory ischemic attack, but who did not exhibit a stroke. The method is based on the determination of the amount of NT-proANP in a sample from said subject. Moreover, the present invention is directed to a method for diagnosing an acute cerebral ischemic event in a subject based on the determination of the amounts of NT-proBNP and NT-proANP in a sample from a subject. The method further comprises the step of calculating a ratio of the amounts of NT-proBNP and NT-proANP. Further envisaged by the present invention are kits and devices adapted to carry out the method of the present invention. | 09-18-2014 |
20140273549 | LOW FORCE ELECTRICAL CONTACT ON METALIZED DEFORMABLE SUBSTRATES - A system for measuring an analyte of interest in a biological fluid includes a test strip for receiving a sample of the biological fluid having multiple contacts formed thereon. A test device includes a circuit board having multiple conducting strips. A connector assembly is fixed to the circuit board and receives the test strip as the test strip moves in an insertion direction to a test position. The connector assembly includes a connector assembly body and multiple conductors. Each of the conductors includes a conductor contact body fixedly connected to the connector assembly body, and a contact arm integrally connected to the conductor contact body and freely extending entirely in the insertion direction. The contact arm is deflected when directly contacted by one of the multiple contacts of the test strip. | 09-18-2014 |
20140273257 | TRANSFERRING BLOOD GLUCOSE MEASURES SEAMLESSLY FROM A HANDHELD GLUCOSE METER - Persons with diabetes often carry a handheld glucose meter as well as a portable computing device, such as a mobile phone. Given the close proximity of these two devices, the portable computing device can serve as a data collector for the glucose measures taken by the glucose meter. Improved techniques are set forth for transferring glucose measures automatically and seamlessly to the patient's portable computing device, including transmitting a single glucose measure automatically in response to navigating away from an interface which displays to the glucose measure. | 09-18-2014 |
20140273256 | DISPLAYING STATUS OF A BLOOD GLUCOSE MEASURE BEING TRANSFERRED WIRELESSLY FROM A HANDHELD GLUCOSE METER - Persons with diabetes often carry a handheld glucose meter as well as a portable computing device, such as a mobile phone. Given the close proximity of these two devices, the portable computing device can serve as a data collector for the glucose measures taken by the glucose meter. Improved techniques are set forth for transferring glucose measures automatically and seamlessly to the patient's portable computing device, including displaying a value for the glucose measure along with an identifier for the portable computing device on a display of the glucose meter during the data exchange with the portable computing device. | 09-18-2014 |
20140262773 | ELECTRODE CONFIGURATION FOR A BIOSENSOR - A biosensor including a capillary chamber having an inner boundary, a working electrode including an effective working electrode portion positioned within the capillary chamber, and a counter electrode including an effective counter electrode portion positioned within the capillary chamber, and with the working and counter electrodes each having a neck that constitutes the sole portion of the electrodes that extends across the inner boundary and out of the capillary chamber. In one embodiment, the effective working electrode portion defines an average working electrode width, and the working electrode neck defines a working electrode neck width that is reduced relative to the average working electrode width. In another embodiment, a ratio between the area of the effective working electrode portion exposed to the capillary chamber and the area of the effective counter electrode portion exposed to the capillary chamber is substantially constant as a position of the inner boundary of the capillary chamber is varied along a length of the working and counter electrode necks. | 09-18-2014 |
20140257251 | CUSTOMIZING NAMES OF INSULIN DELIVERY PROFILES FOR IMPROVED PATIENT SAFETY - Configuration software implements techniques for customizing names of insulin delivery profiles with improved patient safety. The techniques include: receiving a string of characters which serve as a name for a given insulin delivery profile, where the insulin delivery profile includes at least one parameter pertaining to insulin delivery by an insulin pump and is one of a plurality of insulin delivery profiles associated with a given patient; normalizing the string of characters in accordance with a rule set; comparing the normalized string of characters with names for each of the plurality of insulin delivery profiles; and updating the name of the given insulin delivery profile in a pump configuration file residing on the configuration device when the normalized string of characters is unique in relation to the names of the plurality of insulin delivery profiles. | 09-11-2014 |
20140256566 | SEQUENCE TAGS - The present invention relates to a new class of nucleic acid tagging molecules which are essentially free of homopolymer stretches. Such tagging molecules are helpful for effectively tagging a plurality of individual target molecules and detecting said tags with a high degree of accuracy. | 09-11-2014 |
20140255962 | SYMMETRICAL TEST ELEMENT FOR DETECTING AN ANALYTE - Test elements are disclosed for detecting at least one analyte in a body fluid. The test element include at least one strip-shaped carrier element and at least one test field having at least one test chemistry for detecting the analyte. The test element has a symmetrical shape such that the test element may be inserted in one of at least two different correct measurement orientations into a test element receptacle of a testing device, which includes a detection device. In the different orientations, at least one analyte-induced change in the test chemistry of the test field is detectable. Test systems including the test elements and methods of detecting at least one analyte in the body fluid using the test elements also are disclosed. | 09-11-2014 |
20140255959 | CHOLESTEROL OXIDASE MUTANTS, COMPOSITIONS, DEVICES, KITS AND USES THEREOF - Compositions, devices, kits and methods are disclosed for assaying cholesterol with a cholesterol oxidase mutant that has been modified at an amino acid residue involved in the active site. The cholesterol oxidase mutant has reduced oxidase activity while substantially maintaining its dehydrogenase activity. | 09-11-2014 |
20140254170 | BLOOD GLUCOSE TEST STRIP ILLUMINATION DEVICE AND METHOD - A handheld test strip illumination device includes a housing. A strip connector positioned within the housing receives a first portion of a test strip in a test strip test position. A light source is positioned within the housing. A lens/light reflecting device is aligned to receive photons emitted from the light source and direct the photons onto the first portion of the test strip within the strip connector. The first portion of the test strip within the strip connector includes a longitudinal transparent layer receiving the photons emitted from the lens/light reflecting device within the housing. The photons pass through the longitudinal transparent layer and are emitted from the longitudinal transparent layer in a second portion of the test strip positioned outside of the housing, thereby illuminating a dose area of the test strip. | 09-11-2014 |
20140251826 | BIOSENSORS AND BIOSENSOR SYSTEMS WITH Mn2O3 CATALYST AS WELL AS METHODS OF MAKING AND USING THE SAME - Biosensors and biosensor systems are disclosed that have manganese (III) oxide (Mn | 09-11-2014 |
20140249778 | HAND-HELD DEVICE FOR MEASURING AN ANALYTE CONCENTRATION IN A SAMPLE OF A BODY LIQUID - A hand-held device for measuring an analyte concentration in a sample of a body liquid includes a display means for displaying measured values; a measured-value storage for storing measured values; a measuring unit for generating measured values through measurements of the analyte concentration; a clock; a control unit for generating measured value datasets, each containing a measured value supplied by the measuring unit as well as the date and hour of the measurement by which the measured value was obtained, and for writing them into the measured-value storage; and operating elements that can be actuated by the user to set the clock, in which case the control unit will generate a time-correction dataset indicating the amount and direction of the setting effected. The control unit writes time-correction datasets into the measured-value storage so that a chronologically ordered sequence is generated containing time-correction datasets and measured value datasets. | 09-04-2014 |
20140248707 | RELEASE REAGENT FOR VITAMIN D COMPOUNDS - A reagent composition for releasing vitamin D compounds bound to vitamin D-binding protein and an in vitro method for the detection of a vitamin D compound in which the vitamin D compound is released from vitamin D-binding protein by the use of this reagent composition as well as the reagent mixture obtained in this manner. Also disclosed is the use of the reagent compositions to release vitamin D compounds as well as a kit for detecting a vitamin D compound. | 09-04-2014 |
20140248645 | GLUCOSE OXIDASE MUTANTS, COMPOSITIONS, DEVICES, KITS AND USES THEREOF - Compositions, devices, kits and methods are disclosed for assaying glucose with a glucose oxidase mutant that has been modified at an amino acid residue involved in the active site. The glucose oxidase mutant has reduced oxidase activity while substantially maintaining its dehydrogenase activity. | 09-04-2014 |
20140246347 | TRANSPORT PACKAGING FOR PACKAGING HAZARDOUS MATERIALS - Proposed is a transport packaging unit ( | 09-04-2014 |
20140243866 | Method for Producing Analytical Aids - A method for producing analytical aids for obtaining bodily fluid, in particular lancets or microsamplers, in which the aids are formed as a shaped part ( | 08-28-2014 |
20140242705 | HAND-HELD ANALYTICAL DEVICES AND METHODS OF USE THEREOF - Hand-held analytical devices are provided for blood sugar tests. The devices can incorporate a replaceable test tape cassette having a test tape with a plurality of analytical aids and have a tape drive having a DC motor and gearing that can be coupled to the test tape cassette for successive provision of the analytical aids. The devices also include a control device for rotational speed control of the DC motor. Methods also are provided for operating such hand-held analytical devices. | 08-28-2014 |
20140242622 | METHODS OF DETECTING TEST ELEMENTS HAVING DEGRADED TEST CHEMICALS AS WELL AS APPARATUSES INCORPORATING THE SAME - An analytical apparatus is disclosed for detecting at least one analyte in a sample, where in an analyte measurement at least an electrical or optical property changeable by presence of the analyte at least one test chemical of a test element is recorded, and where the analytical apparatus also can perform at least one quality measurement on the at least one test chemical such as an intrinsic luminescence, which is recorded and from the intrinsic luminescence a conclusion is drawn on a quality of the test chemical and thus the test element. Methods also are disclosed for detecting at least one analyte in a sample that include a quality measurement of the at least one test chemical of the test strip. | 08-28-2014 |
20140238118 | ANALYSIS SYSTEM HAVING A MEASUREMENT DEVICE AND TEST ELEMENT - Disclosed herein are portable diagnostic measurement devices for determining at least one analysis parameter of a bodily fluid, in particular for determining an analyte concentration in a bodily fluid as can occur in blood glucose determinations. Also disclosed are analysis systems including the measurement device and at least one disposable test element. The test element can be designed as a carrier strip and can contact a receiving surface of the measurement device at least partially in a flat manner, where the receiving surface is arranged on a narrow side of the housing of the measurement device. | 08-28-2014 |
20140234978 | LABORATORY SAMPLE DISTRIBUTION SYSTEM, LABORATORY SYSTEM AND METHOD OF OPERATING - A laboratory sample distribution system is presented. The laboratory sample distribution system comprises a plurality of container carriers. The container carriers each comprise at least one magnetically active device such as, for example, at least one permanent magnet, and carry a sample container containing a sample. The system further comprises a transport plane to carry the multiple container carriers and a plurality of electro-magnetic actuators stationary arranged below the transport plane. The electro-magnetic actuators move a container carrier on top of the transport plane by applying a magnetic force to the container carrier. The system also comprises at least one transfer device to transfer a sample item, wherein the sample item is a container carrier, a sample container, part of the sample and/or the complete sample, between the transport plane and a laboratory station such as, for example, a pre-analytical, an analytical and/or a post-analytical station. | 08-21-2014 |
20140234879 | DYNAMIC OF SFLT-1 OR ENDOGLIN/PLGF RATIO AS AN INDICATOR FOR IMMINENT PREECLAMPSIA AND/OR HELLP SYNDROME - Diagnostic methods and tools relating to diagnosing whether a pregnant subject is at risk for developing preeclampsia and/or early-onset preeclampsia within a short period of time. The methods include determining the amounts of the biomarkers sFlt-1 or Endoglin and PIGF in a first and a second sample of said subject, said first sample being obtained prior to said second sample; calculating a first ratio from the amounts of sFlt-1 or Endoglin and PIGF determined in the first sample, and a second ratio from the amounts of sFlt-1 or Endoglin and PIGF determined in the second sample; and comparing the value of the first and the second ratio, whereby a subject being at risk for developing preeclampsia within a short period of time is diagnosed if the value of the second ratio is increased compared to the value of the first ratio by a factor of at least about 3. | 08-21-2014 |
20140234065 | LABORATORY SAMPLE DISTRIBUTION SYSTEM AND CORRESPONDING METHOD OF OPERATION - A laboratory sample distribution system is presented. The laboratory sample distribution system comprises a number of container carriers. The container carriers each comprise at least one magnetically active device such as, for example, at least one permanent magnet, and carry a sample container. The system further comprises a transport plane to carry the container carriers and a number of electro-magnetic actuators being stationary arranged below the transport plane. The electro-magnetic actuators move a container carrier on top of the transport plane by applying a magnetic force to the container carrier. | 08-21-2014 |
20140231680 | METHOD AND APPARATUS FOR DETECTING CLOTS IN A LIQUID AND LABORATORY AUTOMATION SYSTEM - A method for detecting clots in a liquid is presented. The liquid is in a sample container. Light is irradiated having a first wavelength to the sample container by a first light source at a changeable vertical irradiating position (P | 08-21-2014 |
20140231217 | LABORATORY SAMPLE DISTRIBUTION SYSTEM AND CORRESPONDING METHOD OF OPERATION - A laboratory sample distribution system is presented. The system comprises a plurality of container carriers. The container carriers each comprise at least one magnetically active device such as, for example, at least one permanent magnet, and carry a sample container containing a sample. The system also comprises a transport device. The transport device comprises a transport plane to carry the plurality of container carriers and a plurality of electro-magnetic actuators stationary arranged below the transport plane. The electro-magnetic actuators move a container carrier placed on top of the transport plane by applying a magnetic force to the container carrier. The transport device also comprises a control device to control the movement of the container carriers on top of the transport plane by driving the electro-magnetic actuators. The control device controls the movement such that more than two container carriers are movable simultaneously and independently from one another. | 08-21-2014 |
20140220604 | TROPONIN AND BNP BASED DIAGNOSIS OF RISK PATIENTS AND CAUSE OF STROKE - Method for early differentiation of whether a subject suffers from cardioembolic stroke or from non-cardioembolic ischemic stroke based on the determination of the amount of a cardiac Troponin in a sample from a subject who is suffering from ischemic stroke, the sample obtained not more than 24 hours after the onset of symptoms of ischemic stroke. Kits and devices adapted to carry out the methods are also provided. | 08-07-2014 |
20140219998 | ARMET AS A MARKER FOR CANCER - Disclosed is a method aiding in the assessment of cancer. More specifically disclosed is the use of the arginine-rich metastasized in early tumors protein (=ARMET) as a universal marker of different cancer types. ARMET aids in the assessment of pulmonary or lung cancer (LC) or of colon cancer, e.g., of non-small cell lung carcinoma (NSCLC) or colorectal cancer (CRC), but also likely of other specific types of cancer. Such specific cancer types are, e.g., breast, ovary, cervix, head and neck, endometrium, melanoma, bladder, kidney, pancreas, prostate, esophagus, stomach or bile duct cancer. Further disclosed is a method for assessing cancer from a liquid sample, derived from an individual by measuring ARMET in the sample. Measurement of ARMET can, e.g., be used in the early detection of cancer or in the surveillance of patients who undergo surgery. | 08-07-2014 |
20140219712 | TEST STRIP EJECTOR FOR MEDICAL DEVICE - A system for receiving and ejecting a fluid testing device test strip includes a strip connector having first and second guide rails, and divider walls each having a channel. A sled has first and second legs connected to a cross member. Each leg has a contact leg extending inwardly from a chamfered end. The first and second legs when positioned parallel to the guide rails have the contact leg captured in the divider wall channels retaining the sled in sliding contact with the guide rails for motions in loading and ejection directions. A mechanism assembly is movably connected to the fluid testing device. The cross member is coupled so operation in a first direction displaces the sled in the loading direction positioning the sled in a test strip test position, and opposite operation positions the contact legs in direct contact with and ejects the test strip. | 08-07-2014 |
20140212958 | LYSIS AND REVERSE TRANSCRIPTION FOR MRNA QUANTIFICATION - The present invention is directed to a method for performing an RT-PCR for amplifying a target RNA including the steps of (i) cultivation of a population of adherent cells in a cell culture vessel (ii) lysis of the population of adherent cells which is supposed to contain the target RNA in the sample vessel with a lysis buffer comprising between 0.05 M and 1 M of a chaotropic agent (iii) adding reagents to the sample vessel which are necessary to perform a reverse transcription reaction such that the chaotropic agent is present in a concentration of about 10 to 60 mM in the sample vessel, and reverse transcribing the target RNA and (iv) amplifying the first strand cDNA by means of subjecting the sample to multiple cycles of a thermocycling protocol. | 07-31-2014 |
20140212903 | AZO MEDIATORS AND METHODS OF USE THEREOF - Azo compounds are disclosed that do not form azoxy dimers and that do not have any reactive nitroso groups. Also disclosed are use of the azo compounds as mediators in optical and electrochemical diagnostic methods, as well as detection reagents, kits and test elements that include such azo compounds and that can be used in the diagnostic methods. | 07-31-2014 |
20140207022 | Method for the mask-etching of a piercing element - A method is disclosed for the mask-etching of a piercing element having an elongate shaft, a distally protruding tip, a proximal holding part, and a laterally open collecting channel that collects bodily fluid and extends along the shaft as far as the area of the tip, wherein a side of a double-sided etching mask is applied respectively to the two sides of a substrate and, under the action of an etching agent, the piercing element is formed as a part made by chemical blanking, wherein a channel side of the etching mask is provided with a channel etching slit for unilateral etching of the collecting channel. | 07-24-2014 |
20140206024 | STABLE NAD/NADH DERIVATIVES - The present invention provides for stable nicotinamide adenine dinucleotide (NAD/NADH) and nicotinamide adenine dinucleotide phosphate (NADP/NADPH) derivatives of formula (I), enzyme complexes of these derivatives and their use in biochemical detection methods and reagent kits. | 07-24-2014 |
20140194818 | Skin Securable Drug Delivery Device With A Shock Absorbing Protective Shield - Disclosed is a skin securable therapeutic fluid dispensing device that includes a reservoir adapted to retain therapeutic fluid, a pump driving mechanism, and at least one housing configured to accommodate the reservoir and the pump driving mechanism, with at least a portion of the at least one housing defining at least a portion of the reservoir. The device also includes a shield coupled to the at least one housing, the shield configured to protect, at least in part, the reservoir from application of external forces thereon. | 07-10-2014 |
20140193845 | USE OF SFRP-3 IN THE ASSESSMENT OF HEART FAILURE - Disclosed is a method for assessing heart failure in vitro including the steps of measuring in a sample the concentration of the marker SFRP-3, of optionally measuring in the sample the concentration of one or more other marker(s) of heart failure, and of assessing heart failure by comparing the concentration determined in for SFRP-3 and the concentration(s) determined for the optionally one or more other marker to the concentration of this marker or these markers as established in a reference population. Also disclosed are the use of SFRP-3 as a marker protein in the assessment of heart failure, a marker combination comprising SFRP-3 and a kit for measuring SFRP-3. | 07-10-2014 |
20140191709 | Handheld Medical Device Simultaneous Charging And In Vivo Analyte Sampling Systems And Methods - A handheld medical device that simultaneously charges its re-chargeable battery and measures one or more characteristics of a bodily fluid is taught. The handheld medical device includes a re-chargeable battery, a wireless power receiver, a battery charging module, and a measurement module. The re-chargeable battery is electrically connected to provide power to components of the handheld medical device. The wireless power receiver outputs power received wirelessly, via an antenna, from a wireless power transmitter that is external to the handheld medical device. The battery charging module selectively charges the re-chargeable battery based on the power received wirelessly from the wireless power transmitter. While the handheld medical device is not connected by wire to any other device, the measurement module measures a characteristic of a sample of a bodily fluid simultaneously with the battery charging module charging the re-chargeable battery. | 07-10-2014 |
20140187652 | L-FABP BASED DIAGNOSIS OF KIDNEY INJURY AFTER AN ACUTE EVENT OR AFTER A SURGICAL INTERVENTION - Systems and methods for diagnosing acute kidney injury following an acute event or surgical intervention, based on assessing the biomarker L-FABP. Also, systems and methods for predicting the risk of an individual to suffer from a kidney injury after an acute event or surgical intervention in the future. | 07-03-2014 |
20140186213 | TEST TAPE CASSETTE AND ANALYTICAL TEST TAPE THEREFOR - A test tape cassette is disclosed that includes a cassette housing and an analytical test tape. The test tape includes a plurality of analytical test elements, a spreading fabric for applying a body fluid, and an underlying reagent layer for detecting an analyte in the body fluid. The cassette housing has an application tip that has a guide path extending longitudinally to the test tape in an arched-shape and is uncurved at right angles thereto for supporting the test tape in a kink-free manner. The guide path has an apex area with a central opening that delimits a measuring window for an optical measurement on the test elements. | 07-03-2014 |
20140180241 | Method For Configuring An Insulin Pump With Configuring Device - An insulin pump is configurable by a configurator. The pump has parameter blocks, each with a respective parameter and an associated restriction setting, and the configurator has an authorization level. Configuring the pump includes receiving, by the configurator, a request to access a parameter on the pump. The method also includes identifying, by the configurator, the parameter block that includes the parameter. Moreover, the method includes retrieving, by the configurator from the pump, the parameter and the associated restriction setting, and comparing, by the configurator, the authorization level of the configurator to the restriction setting. Also, the method includes determining, by the configurator, whether the configurator is authorized to write to the parameter block based on the comparison. Additionally, the method includes writing, by the configurator, to the parameter block on the insulin pump in response to a determination that the configurator is authorized to write to the parameter block. | 06-26-2014 |
20140180238 | Pump Controlling Device That Obtains Parameter Values From Insulin Pump For Executing Functions - A method of operating an insulin treatment system that includes an insulin pump and a pump controlling device is disclosed. The method includes receiving, by the pump controlling device, a request to execute a function that is included on the pump controlling device. The function is governed by a rule having a parameter. The method also includes requesting, by the pump controlling device, a value for the parameter from the insulin pump, and receiving the value from the insulin pump. Also, the method includes executing, by the pump controlling device, the function using the received value for the parameter. | 06-26-2014 |
20140180210 | Dosing Unit for an Ambulatory Infusion Device - A dosing unit for an infusion pump device is disclosed having a piston pump with a pump cylinder and a plunger arranged within said cylinder, coaxially arranged along a longitudinal axis. The plunger has a shaft with a thread and the cylinder has a threaded sleeve part with a thread. The two threads engaging with each other in such a way that a rotational movement of the plunger around the longitudinal axis results in an additional linear displacement of the plunger along said longitudinal axis. A separate bias force element biases the two threads in regard to each other along the longitudinal axis, such that the threaded engagement of inner thread and outer thread is free of play independent of a direction of a rotational movement and linear displacement of the plunger in regard to the cylinder. | 06-26-2014 |
20140174837 | SYSTEM FOR MANAGING BULK LIQUIDS AND/OR SOLIDS - A system for managing of bulk liquids and/or bulk solids for in-vitro diagnostics is disclosed. The system comprises a sample processing unit and a container unit for receiving a supply container supplying the sample processing unit with a bulk liquid/solid and/or a waste container receiving waste from the sample processing unit. The system further comprises a weight measuring device comprising a loading plate, a base and a force measuring cell. The force measuring cell comprises a sensor comprising a tensioned sensor wire. The loading plate is biased with respect to the base by a weight applied to the loading plate by a container and to transfer force to the force measuring cell. The transferred force causes a deformation of the force measuring cell and a change in tension of the sensor wire causing a change in vibrational frequency resulting in a signal indicative of the weight of the container. | 06-26-2014 |
20140172449 | METADATA TAGGING SYSTEM FOR A DIABETES MANAGEMENT SYSTEM OF DEVICES - A diabetes management system having a reliable data management scheme is disclosed. The system comprises a plurality of devices, each device performing a different function relating to treatment of diabetes. Each device has a device identifier and each device generates data records relating to the function of the device. Each device includes a metadata generator configured to generate a metadata tag for a data record generated by the device. A metadata tag includes the device identifier of the corresponding device, a record identifier, and a source identifier indicating whether the record was originated by a human or the device. The system further includes a diabetes management device in communication with the plurality of devices and configured to manage records received from the plurality of devices. When a first device of the plurality of devices generates a new record to be communicated to the diabetes management device, the metadata generator of the first device generates a new unique record identifier and a new metadata tag based on the new unique record identifier and the device identifier of the first device, and the first device propagates the new record and the new metadata tag to the second device. | 06-19-2014 |
20140170636 | DEVICE AND METHOD FOR TRANSFERRING REACTION VESSELS - A method and an automated system for testing liquid samples comprising a reaction vessel transferring device are presented. A first analytical unit for running a first diagnostic test comprises a rotatable first vessel holder detachably holding reaction vessels. A second analytical unit for running a second diagnostic test comprises a stationary linear second vessel holder detachably holding reaction vessels. The transferring device comprises a gripper for gripping a reaction vessel and transfers reaction vessels from the first vessel holder to the second vessel holder and/or vice versa. The device is translatable parallel to the second vessel holder and the gripper moves along a curved path between a picking position and a reaction vessel seat of the second vessel holder. | 06-19-2014 |
20140166482 | TEST STRIP EJECTOR FOR MEDICAL DEVICE - A system and method for receiving and ejecting a test strip of a fluid testing device. The system includes parallel first and second guide rails defining a rail cavity between the guide rails. A sled includes a sled post and opposed first and second side leg sets each having at least one deflectable leg. Each of the deflectable legs is externally slidably engaged to one of the guide rails limiting the sled to only sliding motion in either a loading direction or an opposite ejection direction. An actuator arm is rotatably connected to a mechanism assembly. The sled post is received in an actuator arm slot. Actuator arm rotation in a loading rotational direction displaces the sled in the loading direction in a sliding motion. Subsequent opposite rotation of the actuator arm in an ejection rotational direction displaces the sled in the ejection direction and ejects the test strip. | 06-19-2014 |
20140163338 | Analyte Sensor with Slot Antenna - A medical device for detecting at least one analyte in a body fluid is disclosed. The medical device includes at least one implantable functional element and at least one driver having at least one electronic component. The functional element is connectable to the driver. The driver includes a housing having at least one metal housing and at least one wireless communication device. The metal housing has at least one slot structure. The communication device is adapted to communicate through the slot structure with an external apparatus. | 06-12-2014 |
20140148756 | INFUSION AND SENSING DEVICE WITH BATTERY CHARGING AND DATA TRANSFERRING MECHANISMS - Disclosed is a portable ambulatory fluid delivery device. The device includes a dispensing unit to dispense therapeutic fluid, the dispensing unit including one or more rechargeable batteries, a housing to retain the one or more rechargeable batteries, a reservoir to contain the therapeutic fluid, a driving mechanism to cause delivery of the therapeutic fluid from the reservoir to a user's body, and at least one electrical connector to be coupled to a recharging unit to direct electrical power received from the recharging unit to recharge the one or more rechargeable batteries. At least a portion of the housing is securable to a skin of the user. | 05-29-2014 |
20140147913 | Test Element Analysis System with Contact Surfaces Coated with Hard Material - The invention concerns a test element analytical system for the analytical examination of a sample, especially a body fluid, comprising at least one test element with one or more measuring zones and contact areas located on the test element, in particular electrodes or conductor paths, the sample to be examined being brought into the measuring zone to carry out an analysis in order to determine a characteristic measured quantity for the analysis, and an evaluation instrument with a test element holder for positioning the test element in a measuring position and a measuring device for measuring the characteristic change, the test element holder containing contact elements with contact areas which enable an electrical contact between the contact areas of the test element and the contact areas of the test element holder, characterized in that one of these contact areas is provided with an electrically conductive hard material surface. | 05-29-2014 |
20140142540 | TIME SYNCHRONIZATION IMPROVEMENTS FOR INTEROPERABLE MEDICAL DEVICES - A computer-implemented method is presented for synchronizing time between two handheld medical devices that interoperate with each other. The method includes: determining a first time as measured by a first clock residing in the first medical device; determining a second time as measured by a second clock residing in a second medical device; evaluating whether the first clock is synchronized with the second clock; determining whether at least one of the first clock and the second clock was set manually by a user; and setting time of the first clock in accordance with the second time when the second clock was set manually by the user. | 05-22-2014 |
20140142535 | PUMP CONTROLLER THAT CHECKS OPERATIONAL STATE OF INSULIN PUMP FOR CONTROLLING THE INSULIN PUMP - A computer-implemented method of operating a diabetes treatment system that includes an insulin pump and a pump controlling device is disclosed. The method includes receiving, by the device, a request for the pump to perform an operation that is dependent on a specified state of the pump. The method also includes requesting, by the device, a current state of the pump from the pump. Moreover, the method includes receiving, by the device, the current state of the pump. Also, the method includes determining, by the device, whether the current state of the pump matches to the specified state of the pump. Additionally, the method includes sending, by the device to the pump, a command to perform the operation in response to a determination that the current state of the pump matches the specified state of the pump. | 05-22-2014 |
20140142291 | ENZYMATIC SYNTHESIS OF CARBA-NAD - The disclosure concerns the enzymatic synthesis of stable analogues of nicotinamide adenine dinucleotide NAD/NADH and nicotinamide adenine dinucleotide phosphate NADP/NADPH, the so-called “carba-NADs”, i.e. analogues of NAD/NADH or NADP/NADPH, respectively, comprising a carbacyclic sugar instead of ribose. | 05-22-2014 |
20140141465 | HANDLING OF SAMPLE TUBES COMPRISING GEOMETRIC TUBE DATA - A method for handling a sample tube containing a biological sample is presented. A tube label can be attached to the sample tube. The tube label can carry tube data. The tube data can comprise at least geometric tube data descriptive of at least one geometric property of the sample tube. At least the geometric tube data can be read from the tube label by a reader device. At least the geometric tube data from the reader device can be transmitted to a processing device. The processing device for handling the sample tube can be controlled in accordance with the at least one geometric property described by the read geometric data. | 05-22-2014 |
20140135808 | SYSTEM FOR WITHDRAWING BLOOD - The present invention includes a system for withdrawing body fluids. The system includes a drive unit having a plunger which is moved from a resting position into a lancing position in order to carry out a lancing process and a lancing unit containing a lancet with a needle. The plunger and lancet are coupled together by a form fit in order to carry out a lancing process. The invention additionally concerns a method for temporarily extending a needle from a device for withdrawing body fluid as well as a lancing unit that can be attached to the drive unit. | 05-15-2014 |
20140134633 | DETERGENT FREE POLYMERASES - The present invention relates to a formulation of a thermostable DNA polymerase which is completely free of detergents and its particular use in real time polymerase chain reaction (PCR). Such a formulation may be obtained if the selected purification method does not require the addition of a detergent at any purification step. | 05-15-2014 |
20140128804 | COMMUNICATION PROTOCOL THAT SUPPORTS PASS-THRU COMMUNICATION - A private extension of the IEEE 11073 standard for enabling pass-thru communication between a external computing device and a medical device via a diabetes management device is disclosed herein. Within this context, a diabetes management system for configured to allow pass thru communication is described. The system includes a diabetes management device in communication with a external computing device and the first medical device. A pass-thru module of the diabetes management device uses a set of pass-thru commands for establishing a pass-thru communication path and enabling communication between the external computing device and the first medical device, and wherein the set of pass-through commands is defined in compliance with a communication protocol defined in accordance with IEEE standard 11073-20601. | 05-08-2014 |
20140127728 | REAGENT MATERIALS AND ASSOCIATED TEST ELEMENTS - Reagent materials and associated test elements are provided. In one embodiment, a test element having dual functionality includes a first coenzyme-dependent enzyme or a substrate for the first enzyme, a second coenzyme-dependent enzyme or a substrate for the second enzyme, and a coenzyme selected from the group consisting of thio-NAD, thio-NADP, and a compound according to formula (I). In one aspect, the first analyte is hydroxybutyrate and the first enzyme is a hydroxybutyrate dehydrogenase, and the second analyte is glucose and the second enzyme is a glucose dehydrogenase or a glucose oxidase. Other aspects of the subject application are directed to unique reagent materials. Further embodiments, forms, objects, features, advantages, aspects, and benefits shall become apparent from the description and drawings. | 05-08-2014 |
20140124384 | SYSTEMS AND METHODS FOR MULTIPLE ANALYTE ANALYSIS - Systems and methods for multiple analyte analysis are provided. In one embodiment, a method includes determining concentrations of first and second analytes in a sample. The first and second analytes may be, for example, glucose and hydroxybutyrate. In this form, an indication related to the measured concentration of hydroxybutyrate is provided in response to determining that the concentration of hydroxybutyrate is above a predetermined value. In a further aspect of this form, a quantitative indication representative of the measured glucose concentration is automatically provided regardless of the value of the measured glucose concentration. In another embodiment, a system includes a meter configured to interact with a test element to assess first and second analytes in a sample. Further embodiments, forms, objects, features, advantages, aspects, and benefits shall become apparent from the description and drawings. | 05-08-2014 |
20140120561 | ANTIBODY SPECIFICALLY BINDING TO INSULIN-LIKE GROWTH FACTOR-1 - Isolated antibodies that specifically bind to an epitope comprised in the stretch of amino acids ranging from amino acid 76 to amino acid 84 of human insulin-like growth factor-1 precursor (SEQ ID NO:1). Use of the novel antibodies for the sensitive and specific detection of insulin-like growth factor-1, in some embodiments while in the presence of high excess concentration of insulin-like growth factor-2, for example in a bodily fluid sample. | 05-01-2014 |
20140110480 | SYSTEM AND METHOD FOR LOCATING SAMPLE VESSELS - A system and method for locating sample vessels are presented. The system comprises a holder having an array of positions for holding sample vessels. An information tag is attached to the holder for storing and/or retrieving machine-readable information related to the positions of sample vessels with respect to the array of positions. The system further comprises a handheld device capable of reading information on the information tag. The handheld device has an input for inputting information related to a to-be-located sample vessel and an output for outputting a position of the to-be-located sample vessel with respect to the array of positions based on information stored in the information tag. The method comprises inputting information related to a to-be-located sample vessel into the handheld device, reading information stored in the holder's information tag with the handheld device; and outputting a position of the to-be-located sample vessel. | 04-24-2014 |
20140109527 | SYSTEM AND METHOD FOR STORING AND RETRIEVING VESSEL HOLDERS - An automated system and method for storing/retrieving vessel holders is presented. A first storage compartment comprises first storage sections. A first translating mechanism vertically translates one storage section to a loading level for loading holders into the first storage compartment and translates one storage section to a handing-in level for handing in holders to/from an analyzer. A second storage compartment comprises second storage sections. A second translating mechanism vertically translates one second storage sections to a handing-out level and translates one storage section to an unloading level for unloading holders from the second storage compartment. A first transport mechanism comprises a first conveyor for transporting holders from a first storage section at the handing-in level to a handing-over station. A second transport mechanism comprises a second conveyor for transporting holders from the handing-over station to a second storage section at the handing-out level. A controller operates the mechanisms. | 04-24-2014 |
20140107449 | COMMUNICATION PROTOCOL IMPROVEMENT TO RECOVER DATA FROM A CONTINUOUS GLUCOSE MONITOR - Data transmissions between medical devices are governed by various communication protocols. For example, blood glucose measures may be retrieved wirelessly from a continuous glucose monitor in accordance with the ANT wireless communication protocol. Smaller data packets are preferably transferred in a standard data transfer mode which is optimized for speed and power management; whereas, larger data packets are transferred in a file sharing mode. Techniques are presented to address recovering data lost during the standard data transfer mode in an efficient manner and preferably without the use of the file sharing mode. | 04-17-2014 |
20140106467 | PIPETTING UNIT AND METHOD OF PIPETTING A TEST LIQUID - A pipetting unit and a method of using the pipetting unit for pipetting a volume V | 04-17-2014 |
20140106383 | Electrochemical Determination of Factor XA Inhibitors - Methods and devices for determining factor Xa inhibitors, in particular heparins and fractionated or low-molecular-weight heparins, as well as direct factor Xa inhibitors in blood samples. The methods include contacting a blood sample with a detection reagent that contains at least one thrombin substrate having a peptide residue that can be cleaved by thrombin and is amidically bound via the carboxyl end to an electrogenic substance, and with a known amount of factor X reagent and an activator reagent which induces the conversion of factor X into factor Xa. Subsequently, in a second step, the amount or activity of the electrogenic substance that is cleaved from the thrombin substrate by the factor Xa-mediated thrombin activation and/or the time course thereof is determined as the measurement signal using electrochemical methods. In a third step, the amount of the factor Xa inhibitor in the sample of the blood to be analyzed or a measured quantity that correlates therewith, in particular a clotting time that correlates therewith, is determined on the basis of this measurement signal. | 04-17-2014 |
20140102048 | TRANSPORT AND TRANSFER CONTAINER FOR A LIQUID MEDIUM - A production method for producing a transport and transfer receptacle for at least one fluid medium, for example, for at least one sterile liquid is proposed. The method comprises supplying at least one container for receiving the fluid medium. At least one energy unit is supplied. The energy unit effects—for example, complete—emptying of the fluid medium from the container when the transport and transfer receptacle is used. The fluid medium is introduced into the container and the container is closed. The fluid medium is charged with positive pressure, for example, using the energy unit. The positive pressure is maintained until the fluid medium is removed. Furthermore, a transport and transfer receptacle which can be produced according to the production method and which has at least one packaging is proposed. | 04-17-2014 |
20140100435 | SYSTEM AND METHOD FOR ASSESSING RISK ASSOCIATED WITH A GLUCOSE STATE - A system and method is provided for analyzing a glucose state. A method may include identifying a target glucose state and an initial glucose state. The method may include calculating a target return path for a transition from the initial glucose state to the target glucose state. The target return path may comprise at least one intermediate glucose state associated with the transition from the initial glucose state to the target glucose state. The target return path may be calculated based on a hazard associated with the at least one intermediate glucose state of the target return path. | 04-10-2014 |
20140096368 | MARKING METHOD FOR THE REJECT MARKING OF TEST ELEMENTS - The test elements are provided that are adapted to detect at least one analyte in a sample. At least some of the test elements are provided with a defect marking which contains information about defectiveness of the test elements. The test elements include at least one radiation-sensitive material. The test elements are exposed to at least one radiation, the radiation being adapted to induce marking in the form of at least one optically detectable change in the radiation-sensitive material. | 04-10-2014 |
20140094746 | Fluid Delivery System With Electrochemical Sensing Of Analyte Concentration Levels - A system and a method for delivering fluid to and sensing analyte levels in the body of the patient are disclosed. The system includes a dispensing apparatus configured to infuse fluid into the body of the patient and a sensing apparatus configured to be in communication with the dispensing apparatus and further configured to detect a level of analyte concentration in the body of the patient. | 04-03-2014 |
20140083872 | Sensor Device for Detecting an Analyte - A sensor device for detecting at least one analyte in a fluid, in particular in a body fluid, is disclosed. The sensor device includes at least one closed detector chamber and at least one electrical sensor having at least one sensor electrode. The detector chamber can be connected to the fluid in such a way that the analyte can penetrate into the detector chamber. The detector chamber includes at least one detector substance. The detector substance is designed to influence at least one electrical property of the electrical sensor, in particular at least one electrical property of the sensor electrode, depending on a concentration of the analyte in the detector chamber. | 03-27-2014 |
20140080693 | Automated Sample Workcell and Method of Operation - Illustrative embodiments of automated sample workcells and methods of operation are disclosed. The methods may include receiving a first plurality of samples, each of the first plurality of samples being linked to a requested analysis selected from among a plurality of analysis types; assigning at least one centrifugation parameter to each of the first plurality of samples in response to the requested analysis linked to that sample; loading a second plurality of samples into a centrifuge, the second plurality of samples being selected from among the first plurality of samples and comprising samples that have been assigned at least two different centrifugation parameters; determining a centrifugation parameter of highest centrifugation intensity from among the at least two different centrifugation parameters assigned to samples in the second plurality of samples; and centrifuging the second plurality of samples according to a centrifugation protocol comprising the centrifugation parameter of highest centrifugation intensity. | 03-20-2014 |
20140068487 | Computer Implemented Methods For Visualizing Correlations Between Blood Glucose Data And Events And Apparatuses Thereof - Methods and apparatuses for visualizing correlations between blood glucose data and events are disclosed. The methods and apparatus can include presenting an event analysis window on a display communicatively coupled to one or more processors. The event analysis window can include an event type control positioned within the event analysis window and a graphical window positioned within the event analysis window. A plurality of continuous glucose monitoring traces can be plotted within the graphical window. Bolus icons each indicative of a bolus amount and a bolus time can be presented within the event analysis window. Each of the bolus icons can include a bolus indication object that is aligned with the bolus ordinate axis within the graphical window, a bolus time indication object that is aligned with the time abscissa axis within in the graphical window, and a bolus symbol that is presented outside of the graphical window. | 03-06-2014 |
20140066737 | SENSOR FOR MONITORING A CONDITION OF A PATIENT - A sensor may include a substrate having a sensing portion defining a sensor thereon and a circuit mounting portion defining at least one electrically conductive pad that is electrically connected to the sensor. The sensor may be configured to produce a signal indicative of a condition of the patient. An anisotropic medium may be disposed on the circuit mounting portion and may be electrically conductive in a direction through the medium and electrically insulating in directions along the medium. An electrical circuit may be mechanically mounted to the circuit mounting portion of the first substrate via the anisotropic medium with at least one electrically conductive terminal juxtaposed over the at least one electrically conductive pad. The anisotropic medium may establish local electrical contact between the at least one electrically conductive terminal and the at least one electrically conductive pad. | 03-06-2014 |
20140066735 | DIABETES MANAGER FOR GLUCOSE TESTING AND CONTINUOUS GLUCOSE MONITORING - A handheld diabetes management device for managing blood glucose test data and continuous glucose monitoring data includes a port configured to receive a test strip, a wireless transceiver, a communications processor, and a user interface processor. The communications processor communicates with the wireless transceiver to periodically collect glucose measurement data from a continuous glucose monitoring device and to store the glucose measurement data in a first data storage module. The communications processor is operable to consume electrical power at a first rate. The user interface processor communicates with the communication processor to receive the glucose measurement data and operable to display the glucose measurement data on the device. The communications processor operates asynchronously from operation of the user interface processor to collect the glucose measurement data and the user interface processor operates to consume electrical power at a second rate that is higher than the first rate. | 03-06-2014 |
20140066730 | SYSTEM FOR IN-VIVO MEASUREMENT OF AN ANALYTE CONCENTRATION - The analyte concentration, such as glucose, in a human or animal body is measured with an implantable sensor that generates measurement signals. The measurement signals are compressed through statistical techniques to produced compressed measurement data that can is easier to process and communicate. A base station carries the implantable sensor along with a signal processor, memory, and a transmitter. A display device is also disclosed that can receive the compressed measurement data from the base station for further processing and display. | 03-06-2014 |
20140065648 | USE OF BIOMARKERS IN THE ASSESSMENT OF THE EARLY TRANSITION FROM ARTERIAL HYPERTENSION TO HEART FAILURE - Methods and systems for diagnosing functional and/or structural abnormalities of the heart preceding heart failure, and for predicting the risk of developing heart failure, in a subject comprising measuring a cardiac troponin in a sample and comparing the measurement to a reference value. Other markers, including GDF15 and IGFBP7 are also measured in some embodiments. | 03-06-2014 |
20140058749 | GRAPHICAL USER INTERFACE FOR A HANDHELD DIABETES MANAGEMENT DEVICE WITH BOLUS CALCULATOR - According to some aspects of the present disclosure a method for presenting a GUI for modifying medical data on a handheld medical device is disclosed. The method includes determining a correction bolus amount and a meal bolus amount for the patient. The method also includes presenting the GUI on a display of the medical device and presenting the correction bolus amount, the meal bolus amount and a total bolus amount in the GUI. The method also includes presenting a correction bolus amount modification field and a meal bolus amount field in the GUI. The correction bolus amount modification field and the meal bolus amount modification field allow the patient to provide input to modify the correction bolus amount and meal bolus amount, respectively. The method further includes receiving the input and generating an advice history record based on the input. | 02-27-2014 |
20140058237 | HANDHELD DIABETES MANAGEMENT DEVICE WITH BOLUS CALCULATOR - According to some embodiments of the present disclosure, a device and method for determining an allowable amount of blood glucose (bG) of a patient is disclosed. The method further includes receiving a current bG measurement, determining a target bG value, and determining a correction delta bG value based on one or more advice history records. The method includes determining a correction meal rise value and determining a maximum allowed bG value based on the target bG value, the correction delta bG value, and the correction meal rise value. The method includes setting the allowable amount of bG value equal to the maximum allowed bG value when the current bG measurement is greater than the target bG value and determining the allowable amount of bG value using the target bG value and the correction delta bG value when the current bG measurement is less than the target bG value. | 02-27-2014 |
20140052025 | LANCETS FOR BODILY FLUID SAMPLING SUPPLIED ON A TAPE - A supply of lancets for a multi-use lancing device are carried by a tape and sequentially brought from a storage position to an activating position by advancing the tape around a bend. In the lancets' activating position they extend from the tape such that their sharp tips are available for lancing tissue. The carrying tape can be arranged in reel-to-reel format in a housing having a lancing opening. The lancets can be integral with the tape and activated to move the lancet through the lancing opening by moving the tape along its tape path or by translating a dedicated service loop of the tape. The lancets can also be independent from the tape and activated through the lancing opening by a separate lancing actuator. A test media can be included on the carrying tape and the housing can contain a sensor to yield an integrated lancing and testing device. | 02-20-2014 |
20140045719 | DIRECTED SYNTHESIS OF OLIGOPHOSPHORAMIDATE STEREOISOMERS - The trivalent phosphorous atom of a compound is reacted with a reagent in such a manner that a stable phosphate mimetic or a specifier is formed. Phosphoramidites with a phosphorous atom containing at least one hydroxyl residue which is provided with a protective group are reacted for this purpose with a free hydroxyl group: In the first synthesis cycle the hydroxyl group is linked to a solid support via a cleavable or non-cleavable linker. In further synthesis cycles the hydroxyl group is created by cleavage of the protective group from the growing oligomer. This results in formation of a phosphorous acid triester which is reacted with azides. By selecting suitable monomers for the synthesis which have a defined stereoconformation compounds of Formula 1 are produced in a stereocontrolled manner. | 02-13-2014 |
20140045203 | TEST ELEMENT FOR DETECTING AN ANALYTE IN A SAMPLE - The invention relates to a test element for detecting at least one analyte in a sample, in particular for detecting at least one metabolite in a bodily fluid. The test element comprises at least one test field with a test field surface. The test field comprises at least one detection reagent that is adapted to undergo a detectable reaction in the presence of the analyte. The test element further comprises at least one distribution element that has at least one distribution surface facing the test field surface. Between the distribution surface and the test field surface is at least one capillary gap, wherein the capillary gap is adapted to allow a layer of the sample with a layer thickness of no more than 50 μm to form within the capillary gap. | 02-13-2014 |
20140044608 | Analytical Aid - A process for producing an analytical aid for the detection of at least one analyte in a sample, such as a body fluid. The analytical aid includes at least one housing and at least one test element including at least one test chemistry. The process includes the following steps: providing the test element; and producing at least one housing part of the housing at least one shaping process, during which the test element is connected to the housing part. | 02-13-2014 |
20140042017 | SENSOR ELEMENTS WITH A TANTALUM- OR NIOBIUM-CONTAINING BASE LAYER AND METHODS OF PRODUCING THE SAME - Sensor elements are disclosed for the electrochemically analyzing a body fluid, as well as methods of producing and using the same. The sensor elements include an electrically conductive layer structure applied to a non-conductive carrier substrate, where the layer structure includes a continuous base layer of tantalum, niobium or an alloy thereof, and a metallic cover layer formed on the base layer that covers the base layer either over the entire surface or in some regions. The metallic cover layer includes a more noble metal when compared to the base layer. | 02-13-2014 |
20140041443 | ANALYSIS SYSTEM HAVING A MEASUREMENT DEVICE AND TEST ELEMENT - Disclosed herein are portable diagnostic measurement devices for determining at least one analysis parameter of a bodily fluid, in particular for determining an analyte concentration in a bodily fluid as can occur in blood glucose determinations. Also disclosed are analysis systems including the measurement device and at least one disposable test element. The test element can be designed as a carrier strip and can contact a receiving surface of the measurement device at least partially in a flat manner, where the receiving surface is arranged on a narrow side of the housing of the measurement device. | 02-13-2014 |
20140037420 | Laboratory system for handling sample tube racks, an alignment element for sample tube racks and a rack tray receiver assembly - A laboratory system for handling sample tube racks, an alignment element for sample tube racks and a rack tray receiver assembly are disclosed. The laboratory system to handle laboratory sample tube racks comprises a robotic arm ( | 02-06-2014 |
20140032549 | SYSTEM FOR MANAGING INSULIN DOSAGE DATA - A method is provided for managing insulin dosage data collected over a complete day and a partial day. The method includes providing, by an insulin pump, a plurality of insulin dosages over a complete day and a partial day and recording the insulin dosages. The method also includes recognizing a completion of the complete day, recording an end-of-day marker, and associating the end-of-day marker to the dosages delivered during the complete day. Moreover, the method includes identifying complete day dosage data and partial day dosage data. Additionally, the method includes performing a calculation of insulin dosage statistics and/or displaying and distinguishing between the complete day dosage data and the partial day dosage data. The calculation includes the complete day dosage data and excludes the partial day dosage data. | 01-30-2014 |
20140031657 | HANDHELD MEDICAL DEVICE FUNCTIONALITY WITHOUT BATTERY - A processor module includes memory having instructions for executing functions of a handheld diabetes management device and a processor that selectively executes the instructions. Battery terminals electrically connect the processor module with a re-chargeable battery. A receptacle is configured in accordance with a universal serial bus (USB) standard. A component is included for communicating information from the handheld diabetes management device to a user or another device. A multiplexer module relays power from the receptacle to a bus voltage node. A first switching device is connected between the bus voltage node and a second voltage node. The component receives power from the second voltage node. A second switching device is connected between the bus voltage node and a third voltage node. The processor module is directly connected to the bus voltage node and to the third voltage node. | 01-30-2014 |
20140027328 | PACKAGE FOR HYDROPHILIC MEDICAL INSTRUMENTS - A plastic package for hydrophilic articles, in particular for hydrophilically coated medical instruments, is intended to ensure the hydrophilic nature of the enclosed instrument over a long period of time. The package includes at least one receiving compartment with a medical instrument for insertion into body tissue and is characterized in that, after sterilization by radiation, it has a proportion of volatile constituents of ≦0.1 μg/cm2. | 01-30-2014 |
20140025400 | DEVICE, METHOD, AND GRAPHICAL USER INTERFACE FOR SEARCHING, FILTERING AND DISPLAYING EVENT-ALIGNED INFORMATION SETS RELATED TO DIABETES - A device, method, and graphical user interface for displaying diabetes related information sets aligned by the occurrence of a particular event are disclosed. After receiving a request for an event-aligned display of diabetes related information based on an event, a search for a plurality of tagged occurrences of the event and retrieval of an information set for each of the plurality of tagged occurrences is provided. Each information set may include diabetes related information chronologically related to the tagged occurrence. The retrieved information sets is displayed on a display, wherein the retrieved information sets are shown on the display aligned by their tagged occurrences such that all diabetes related information is positioned relative the event based on its chronological relationship with the event. | 01-23-2014 |
20140019396 | INSULIN DOSAGE ASSESSMENT AND RECOMMENDATION SYSTEM - A computer-implemented method is presented for recommending insulin dosage adjustments for a patient having diabetes. The method includes: identifying a plurality of bolus events from patient data; grouping bolus events having a recommended bolus dosage substantially equivalent to the amount of administered insulin into a first subset of bolus events; determining a bolus outcome for each of the bolus events in the first subset of bolus events, where the bolus outcome is expressed in relation to a target range of blood glucose values and is selected from a group including above the target range, in the target range and below the target range; determining whether one of the bolus outcomes is predominant amongst the bolus events in the first subset of bolus events; and generating a recommendation pertaining to insulin dosage for the patient in response to a determination that one of the bolus outcomes is predominant. | 01-16-2014 |
20140018653 | DIFFUSION LAYER FOR AN ENZYMATIC IN VIVO SENSOR - Electrode systems are disclosed for measuring the concentration of an analyte under in vivo conditions, where the systems includes an electrode with immobilized enzyme molecules and an improved diffusion barrier that controls diffusion of the analyte from body fluid surrounding the electrode system to the enzyme molecules. Methods of making and using the system also are disclosed. | 01-16-2014 |
20140017815 | MEASUREMENT OF C-TERMINAL proSP-B - In vitro methods for obtaining an indication of damage in the broncheoalveolar compartment of the lung comprising, measuring C-terminal proSP-B in a bodily fluid sample and comparing the level measured to a reference level of C-terminal proSP-B, wherein an increased level of C-terminal proSP-B is indicative of damage in the broncheoalveolar compartment of the lung. | 01-16-2014 |
20140017682 | HIGH RESOLUTION MELTING ANALYSIS AS A PRESCREENING TOOL - Compositions and methods for determining an increased likelihood of a response to a targeted treatment of a cancer disease including isolating genomic DNA from a patient sample, amplifying a fragment of DNA by means of PCR with a specific pair of amplification primers, determining if the amplified fragment comprises a wildtype sequence or a mutation by means of a High Resolution Melting Analysis (HRM), and correlating the presence or absence of a mutation with an increased likelihood of success of said targeted treatment. Respective primer pairs, compositions and kits are also claimed. | 01-16-2014 |
20140017123 | ANALYTICAL AIDS WITH HYDROPHILIC COATING CONTAINING NANOPARTICLES WITH SILICA STRUCTURE AND METHODS OF PRODUCING AND USING THE SAME - Disclosed herein are analytical aids having a surface coated at least partially with a hydrophilic coating, where the hydrophilic coating includes nanoparticles with silica structure and an average particle size in a range from about 1 nm to about 500 nm. Also disclosed are methods of producing the analytical aids, as well as using the analytical aids in, for example, a sampling device containing the at least partially coated analytical aid. | 01-16-2014 |
20140014677 | HERMETICALLY SEALED TEST STRIP CONTAINER - A test strip container comprising a housing defining a cavity having a dispensing wall, a housing inlet, and a dispensing outlet is presented. The container may also comprise a lid mounted movably on the housing to define a primed position and an unprimed position therebetween. A cartridge may be provided within the cavity and holding a plurality of test strips. The cartridge may have a plunger entrance seal and a strip exit seal. A biasing member may be disposed within the cartridge urging the plurality of test strips towards the dispensing wall to be aligned with the dispensing outlet. A plunger may be provided, and oriented to open the plunger entrance seal through the housing inlet when the lid is in the primed position, and to urge a single test strip from the plurality of test strips through the strip exit seal of the cartridge and the dispensing outlet of the housing when the lid is transitioned from the primed position to the unprimed position. | 01-16-2014 |
20140011290 | COLLECTION OF LIQUID ANALYTICAL SAMPLES FOR CLINICAL ANALYTICAL PURPOSE AND DEVICE THEREOF - A method and analytical device for collecting a sample volume containing at least one analyte of interest from a liquid analytical sample having contaminants disposed at or near the sample surface. The liquid analytical sample is provided. A first pipetting device comprising a first pipetting needle aspirates from an upper region of the liquid analytical sample a portion comprising the contaminants and discards the portion. The first needle is washed with washing liquid. A second pipetting device comprising a second pipetting needle, or a disposable pipetting tip, aspirates the sample volume from the liquid analytical sample after the first pipetting device discards the aspirated portion and discharges the sample volume for analysis. The second needle is washed with washing liquid or disposed of. | 01-09-2014 |
20140005951 | Blood Glucose Measuring Device with Reliable Transmission of Values to an External Device | 01-02-2014 |
20140005507 | TEST STRIP EJECTOR FOR MEDICAL DEVICE | 01-02-2014 |
20140004544 | FEN1 AS A MARKER FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) | 01-02-2014 |
20140004543 | ASC AS A MARKER FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) | 01-02-2014 |
20140001044 | TEST STRIP EJECTOR FOR MEDICAL DEVICE | 01-02-2014 |
20140001043 | PRINTED MEMORY ON STRIP | 01-02-2014 |
20130344516 | ARMET AS A MARKER FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) - An in vitro method aiding in the assessment of chronic obstructive pulmonary disease (COPD). The disclosure further relates to a method for assessing COPD from a sample, derived from an individual, by measuring the protein ARMET in said sample in vitro. | 12-26-2013 |
20130344506 | SEPRASE AS A MARKER FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) - An in vitro method aiding in the assessment of chronic obstructive pulmonary disease (COPD). The disclosure further relates to a method for assessing COPD from a sample, derived from an individual, by measuring the protein Seprase in said sample in vitro. | 12-26-2013 |
20130344505 | APEX1 AS A MARKER FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) - An in vitro method aiding in the assessment of chronic obstructive pulmonary disease (COPD). The disclosure further relates to a method for assessing COPD from a sample, derived from an individual, by measuring the protein APEX1 in said sample in vitro. | 12-26-2013 |
20130344504 | NNMT AS A MARKER FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) - An in vitro method aiding in the assessment of chronic obstructive pulmonary disease (COPD). The disclosure further relates to a method for assessing COPD from a sample, derived from an individual, by measuring the protein NNMT in said sample in vitro. | 12-26-2013 |
20130343964 | TEST ELEMENTS AND METHODS OF PRODUCING THE SAME FOR STUDYING A BODY FLUID SAMPLE - Disclosed herein are methods of producing a test element for studying a body fluid sample. In the methods, a detection layer is covered with a polymeric spreading layer and applied to a support. The spreading layer can be produced by being sprayed onto the detection layer such that the spreading layer has a thickness of at most about 20 μm. Also disclosed are test elements produced by the methods, as well as tape cassettes incorporating such test elements. | 12-26-2013 |
20130331675 | METHOD FOR DISPLAYING MEDICAL DATA BY A MEDICAL DEVICEDURING DISPLAY FAILURE - A medical device and a method for displaying medical data by the medical device are disclosed. In one aspect of the disclosure, a method for displaying medical data by a medical device having a display device and one or more processors is disclosed. The method includes monitoring a condition of the display device and determining, at the medical device, whether the display device is in a failure state based on the monitoring, the failure state being indicative of a malfunction of the display device. When the display device is a failure state, the method includes commanding a slave device to display the medical data and providing the medical data from the medical device to the slave device for display by the mobile device. | 12-12-2013 |
20130324807 | SPACE-SAVING MAGAZINING OF ANALYTICAL AIDS - An analytical magazine is proposed, which comprises a plurality of analytical aids accommodated in chambers. The analytical magazine is arranged to be accommodated in at least two orientations in an analytical system. The analytical magazine is furthermore arranged to provide the analytical system, in the orientations, in each case with a plurality of analytical aids. At least one sampling movement can be executed by means of the analytical aids. The analytical magazine is arranged to make a remagazining of the analytical aids possible. | 12-05-2013 |
20130323857 | NEW IRIDIUM-BASED COMPLEXES FOR ECL - Novel iridium-based Ir(III) luminescent complexes, conjugates comprising these complexes as a label and their application, for example in electrochemiluminescence based detection of an analyte. | 12-05-2013 |
20130323719 | NEW IRIDIUM-BASED COMPLEXES FOR ECL - Novel iridium-based Ir(III) luminescent complexes, conjugates comprising these complexes as a label and their application, for example in the electrochemiluminescence based detection of an analyte. | 12-05-2013 |
20130315486 | METHOD AND APPARATUS FOR DETECTING FOAM ON A LIQUID SURFACE IN A VESSEL - An apparatus and method for detecting foam on a liquid surface in a vessel is presented. The vessel has an upper opening surrounded by a border. The vessel can be a tube-shaped. At least one image is taken from a region suspected to contain foam in the vessel by using an image sensing device that provides corresponding image data. An automatic evaluation of the image is performed on the basis of the image data by a data processing system using an image evaluation program. The at least one image is taken from the top of the vessel through the open upper opening onto the liquid surface. The image evaluation program of the data processing system identifies foam areas and non-foam areas in the image and provides information about the presence or absence of foam areas in the image as a result of the image evaluation. | 11-28-2013 |
20130303768 | METHOD AND SUBSTANCES FOR PREPARATION OF N-SUBSTITUTED PYRIDINIUM COMPOUNDS - A method for the synthesis of N-substituted 3-acylated pyridinium compounds by reacting a pentamethine precursor with a primary amine. | 11-14-2013 |
20130302221 | HAND-HELD MEDICAL DEVICE - Disclosed herein are hand-held medical devices, such as blood glucose meters, that include a housing with a cassette compartment for receiving an exchangeable test tape cassette, a drive assembly comprising an electric motor and a gear arrangement adapted for rotating a tape spool of the test tape cassette, where the gear arrangement has a worm drive in which a worm meshes with a worm wheel and a multistage speed-reducing unit comprising a plurality of spur gears arranged between the worm wheel and an output gear that can be directly coupled to the tape spool. | 11-14-2013 |
20130297224 | Method for evaluating a set of measurement data from an oral glucose tolerance test - A method is provided for evaluating a set of measurement data from an oral glucose tolerance test. The method may include calculating a similarity measure that quantifies the similarity between a time profile of the series of measured data of the glucose concentration and a corresponding glucose reference profile. The method may include calculating a further similarity measure that quantifies the similarity between the profile of the series of measured values of the further analyte concentration and the corresponding analyte sample profile, wherein the data set is represented by a point in a vector space that comprises coordinate axes that are formed by the similarity measures, whereby the coordinates of said point contain the calculated values of the similarity measures. The method also may include evaluating the position of the point with respect to reference points, which each represent a defined state of health, in order to calculate a parameter that specifies the state of the glucose metabolism of the patient. | 11-07-2013 |
20130296664 | Biosensor and Method for Providing a Biosensor - A biosensor is proposed for insertion into the subcutaneous tissue of a user wherein the biosensor includes at least one flexible substrate ( | 11-07-2013 |
20130288267 | DETECTION OF A POLYPEPTIDE DIMER BY A BIVALENT BINDING AGENT - A bivalent binding agent, capable of binding a polypeptide dimer, consisting of two monovalent binders linked to each other via a linker, the first monovalent binder binds an epitope of a first target polypeptide comprised in said dimer and the second monovalent binder binds to an epitope of a second target polypeptide comprised in said dimer. Each monovalent binder has a Kdiss in the range of 5×10 | 10-31-2013 |
20130288266 | DETECTION OF A POSTTRANSLATIONALLY MODIFIED POLYPEPTIDE BY A BI-VALENT BINDING AGENT - A bi-valent binding agent having a first monovalent binder that binds to a polypeptide epitope of a target polypeptide, a second monovalent binder that binds to a posttranslational polypeptide modification on the target polypeptide and a linker. Further disclosed are methods for the detection of a posttranslationally modified target polypeptide, for making the disclosed bi-valent binding agent, and for use of the disclosed bi-valent binding agent in histological staining procedures. | 10-31-2013 |
20130280130 | AUTOMATIC ANALYZER - Unlike conventional reagent storing means of an analyzing unit having a cold-storage function, replacement reagent storing means having no cold-storage function requires reagent management of a higher order. An automatic analyzer is provided that manages the placing elapsed time for a reagent vessel in replacement reagent storing means | 10-24-2013 |
20130280129 | AUTOMATIC ANALYZER - An automatic analyzer includes: first reagent storing means for storing a plurality of the reagent containers; second reagent storing means for storing a replacement reagent container in addition to the first reagent storing means; transfer means for transferring the reagent container from the second reagent storing means to the first reagent means; and a storing portion for storing the reagent container discharged from the second reagent storing means. The automatic analyzer includes control means for exercising control such that the information write means writes reagent information on the information recording medium immediately before the reagent container is transferred from the second reagent storing means to the first reagent storing means or immediately before the reagent container is discharged from the second reagent storing means to the storing portion. | 10-24-2013 |
20130277234 | SYSTEMS AND METHODS TO COMPENSATE FOR SOURCES OF ERROR DURING ELECTROCHEMICAL TESTING - A method is disclosed for determining analyte concentration that includes applying a first electrical potential excitation pulse to a body fluid sample in an analyte sensor, and a first current response of the body fluid sample to the first pulse is measured. A second excitation pulse is applied to the body fluid sample in the analyte sensor, and a second current response of the body fluid sample to the second pulse is measured. An analyte level in the body fluid sample is determined by compensating for sources of error based on the first current response to the first pulse. | 10-24-2013 |
20130258832 | TEST ELEMENT HAVING AN OPTICAL DATA STORAGE, DEVICE FOR READING THE OPTICAL DATA STORAGE OF THE TEST ELEMENT AND MEASURING SYSTEM THEREOF - A test element is disclosed for analyzing a human or animal body fluid sample. The test element includes a substrate carrying a test field with a reagent for effecting a detection reaction when exposed to the body fluid sample, and an optical data storage in which data regarding the test element, preferably calibration data, is stored. Accordingly, the data storage is a holographic data storage. A hologram reader also is disclosed for reading the data storage of such a test element. Moreover, a hologram label and a method for manufacturing a hologram label are disclosed, as is a medical product including a holographic data storage in which data regarding the product is stored. | 10-03-2013 |
20130254697 | Methods, Systems And Computer Readable Media For Modifying Parameters Of A Configuration File - Disclosed is a method of configuring a medical device through utilization of a computing device that includes a user interface, a processor and memory. The method includes the steps of determining whether a configuration file contains a focal modified parameter, displaying the focal modified parameter, prompting a manual re-entry of the displayed focal modified parameter, receiving through the user interface the manual re-entry of the displayed focal modified parameter, and utilizing the processor to automatically determine whether the manual re-entry of the displayed focal modified parameter matches the displayed focal modified parameter. | 09-26-2013 |
20130253439 | Container For Storing Medical or Pharmaceutical Liquids - A container for storing a medical or pharmaceutical liquid comprising a storage compartment for storing the liquid comprising, an inlet opening for filling the storage compartment and an outlet opening for discharging liquid out of the storage compartment is presented. A hydrophilic membrane layer is arranged within the storage compartment which is gas-tight in a wet condition and which at least covers the outlet opening and contacts the liquid stored within the storage compartment. A dosing assembly and a device for automated release of a medical or pharmaceutical liquid comprising and/or capable of using at least one container are also disclosed. | 09-26-2013 |
20130246096 | Systems and Methods for Performing an Analysis of Measured Blood Glucose Values - A system and method for analyzing measured blood glucose values is disclosed, wherein the system includes a display device, a memory device, and a processor having program instructions which when executed cause the processor to provide blood glucose measurement information including a plurality of measured blood glucose values collected within a measurement time frame, perform a pre-analysis of the blood glucose measurement information, provide analysis data representing statistical blood glucose level information for the plurality of measured blood glucose values by performing an analysis of the plurality of measured blood glucose values, and provide output analysis data representing the analysis data, wherein the provision of analysis data and/or the provision of output analysis data are performed if, in the step of performing the pre-analysis, at least one of the following control checks is positive a fidelity check, and an adherence check. | 09-19-2013 |
20130243664 | MICROFLUIDIC ELEMENT FOR ANALYSIS OF A SAMPLE LIQUID - A microfluidic element for analysis of a fluid sample having a substrate and a microfluidic transport system having a channel structure enclosed by the substrate and a covering layer. The channel structure comprises a channel with two side walls as well as a chamber that is in fluid communication with the channel. The chamber has a chamber wall with an inlet orifice. The channel comprises a channel section and a valve section adjoining the channel section, wherein the valve section is in fluid communication with the inlet orifice in the chamber wall in such a way that a fluid can flow from the channel through the valve section and into the chamber. The valve section has a fluid transport cross-section, which enlarges in flow direction. The fluid transport cross-section in the valve section is greater than the fluid transport cross-section in the preceding channel section. | 09-19-2013 |
20130239390 | ANALYTICAL DEVICE WITH LANCET AND TEST ELEMENT - The invention concerns an analytical device containing a lancet comprising a lancet needle and a lancet body, the lancet needle movable relative to the lancet body and the lancet body composed, in the area of the tip of the lancet needle, of an elastic material in which the tip of the lancet needle is embedded, and an analytical test element connected to the lancet body. The invention also concerns an analytical device containing a lancet comprising a lancet needle and a lancet body in the form of a hollow body in the area of the tip of the lancet needle and surrounds the tip of the lancet needle, the lancet needle movable relative to the lancet body and the hollow body composed at least partially of an elastic material, and an analytical test element connected to the lancet body. The invention concerns a process for manufacturing an analytical device. | 09-19-2013 |
20130237881 | INSTRUMENTS AND SYSTEM FOR PRODUCING A SAMPLE OF A BODY FLUID AND FOR ANALYSIS THEREOF - Instrument for producing a sample of body liquid for analysis by piercing the skin with a lancing element having a skin piercing tip. The instrument has a housing and a lancing drive for driving a lancing element connected thereto in a puncturing movement. A pressure ring surrounds a skin contact opening and is adapted for pressing against the skin such that the skin bulges into the opening for promoting expression of body fluid. The skin contact opening has an opening area corresponding to a circle with a diameter of at least 3 mm and at most 8 mm, and the instrument comprises a pressing force control device for controlling the pressing force between the pressure ring and the skin at the time of triggering the puncturing movement, to be at least 3 N and at most 8 N. | 09-12-2013 |
20130236916 | D-DIMER, TROPONIN, AND NT-PROBNP FOR PULMONARY EMBOLISM - The present invention relates to a method of diagnosing acute pulmonary embolism (PE) in a subject including a) determining the amount of fibrin-fibrinogen degradation products, in particular D-dimer in a sample of the subject; b) determining the amount of a natriuretic peptide in a sample of the subject; c) determining the amount of a cardiac troponin in a sample of the subject; and d) comparing the amounts determined in steps a) to c) to reference amounts, thereby establishing the diagnosis. Included is also a method of deciding on a therapy of a subject diagnosed with PE and a method of monitoring the therapy. | 09-12-2013 |
20130236376 | Microfluidic Test Carrier for Apportioning a Liquid Quantity Into Subquantities - A microfluidic test carrier having a substrate, covering layer, and capillary structure formed in the substrate is provided. The capillary structure is enclosed by the substrate and covering layer and comprises a receiving chamber, sample chamber and connection channel between the receiving and sample chambers. The receiving chamber has two boundary surfaces and a side wall, wherein one boundary surface forms the bottom and the other forms the cover. The receiving chamber has a surrounding venting channel and dam between the receiving chamber and venting channel. The dam and venting channel form a capillary stop configured as a geometric valve, through which air from the receiving chamber can escape into the venting channel. The connecting channel between the venting channel outflow and sample chamber inflow controls fluid transport from the receiving chamber into the sample chamber. The capillary stop is configured to prevent autonomous fluid transport from the receiving chamber. | 09-12-2013 |
20130232425 | DETERMINATION OF A TERMINAL'S POSITION FOR DISPLAYING A GUI ELEMENT - Computer-implemented method for providing access control to a function of an analyzer is presented. A user's log-in data is received from a first data entry terminal. Information descriptive of a position of the first data entry terminal is obtained. It is determined whether the position of the first data entry terminal is within a physical operating (PO) area of the analyzer. A user activatable position sensitive (PS) GUI element is displayed on the first data entry terminal if the position of the first data entry terminal is determined to be within the PO area. The activatable PS GUI element triggers, upon activation, the execution of the function. The execution of the function comprises the execution of a physical action by the analyzer. The display of the user activatable PS GUI element is otherwise prohibited or a non-activatable PS GUI element indicative of the function is displayed. | 09-05-2013 |
20130230428 | DIAGNOSTIC TAPE UNIT AND DIAGNOSTIC MEASURING SYSTEM - The invention concerns a diagnostic tape unit with a test tape that can be wound onto a spool which comprises a transport tape and a plurality of test elements mounted thereon, where the test elements have an analytical reagent layer, a carrier foil supporting the reagent layer and a piece of adhesive tape connecting the carrier foil with the transport tape, and where the front side of the reagent layer facing away from the carrier foil is designed for the application of a sample substance. According to the invention it is proposed that the test elements in combination with the light transmitting transport tape in each case form an optical multi-layer system for a rear-side reflection-photometric measurement of the reagent layer. | 09-05-2013 |
20130224758 | USE OF SIGNAL ENHANCING COMPOUNDS IN ELECTROCHEMILUMINESCENCE DETECTION - The application provides methods for the detection of an analyte in a sample by electrochemiluminescence using certain reagent compositions. Reagent compositions, reagent kits for measuring electrochemiluminescence (ECL) and electrochemiluminescence detection methods using the reagent compositions are disclosed. In particular, the application relates to the use of novel combinations of compounds, which can be used in said measurements to provide improved ECL assay performance. | 08-29-2013 |
20130221090 | Devices and Methods for Capturing Optical Barcodes - A barcode reader for capturing a barcode connected to a moving carrier is proposed having at least one optical barcode detector for at least one-dimensional capture of information modules of the barcode. The barcode reader furthermore comprises at least one optical clock track detector for capturing clock track modules of a clock track of the barcode and at least one optical reference detector for capturing at least one item of reference information of the barcode. The barcode reader is configured to determine a direction of movement of the carrier from at least one signal from the clock track detector and at least one signal from the reference detector. | 08-29-2013 |
20130217138 | TEST ELEMENT FOR DETERMINING A BODY FLUID AND MEASUREMENT METHOD - A test element for determining a body fluid is provided. The test element, in particular for determining the blood glucose level, includes a detection region which is charged with a reagent sensitive to the body fluid. A function element is arranged in or adjacent to the detection region for detecting at least one status parameter for the detection region, such that the functional element can be evaluated by means of a status measurement. A method for measuring the test element is also disclosed. | 08-22-2013 |
20130216433 | DIAGNOSTIC TAPE CASSETTE - A diagnostic tape cassette is disclosed that includes an analytical test tape, a supply spool for winding off unused test tape and a take-up spool for winding used test tape, a housing and a rotational lock for the take-up spool at least against inadvertent unwinding of test tape. The rotational lock includes one of a locking teeth arrangement, friction elements, and a catch spring and spring latch arrangement. | 08-22-2013 |
20130213822 | ELECTROCHEMICAL AFFINITY BIOSENSOR SYSTEM AND METHODS - The present invention provides novel osmium-based electrochemical species for the detection of wide variety of analytes using immunological techniques. The present invention also provides diagnostic kits and test sensors supporting electrode structures that can be used with the osmium-based electrochemical species. The test sensor can be fabricated to support interdigitated arrays of electrodes that have been designed to provide amplification of the electrical signal amplification desired to analyze analytes that may be present at low concentrations. | 08-22-2013 |
20130212381 | SYSTEM AND METHOD FOR CONTROLLING AUTHORIZED ACCESS TO A STRUCTURED TESTING PROCEDURE ON A MEDICAL DEVICE - Methods and systems for authorizing access to a medical device are disclosed. The methods and systems use authorization certificates to allow and prevent access to one or more operations of the medical device. The methods and systems also allow the tracking of changes made to the medical device by an authorized user. | 08-15-2013 |
20130210009 | CONJUGATE BETWEEN A THIOPHILIC SOLID PHASE AND AN OLIGONUCLEOTIDE COMPRISING A THIOOXONUCLEOTIDE - An oligonucleotide-solid phase conjugate, wherein the solid phase is thiophilic and the oligonucleotide comprises at least one thiooxonucleobase according to Formula I, | 08-15-2013 |
20130203628 | SET OF OLIGONUCLEOTIDE PROBES AS WELL AS METHODS AND USES THERETO - The present disclosure relates to a set of at least 100 single-stranded oligonucleotide probes directed against (or complementary to) portions of a genomic target sequence of interest. The present disclosure also relates to a method of detecting a genomic target sequence of interest using the set of oligonucleotide probes and a method of generating the set of oligonucleotide probes. Further, the present disclosure relates to a kit comprising the set of oligonucleotide probes and at least one further component. | 08-08-2013 |
20130203120 | METHOD FOR CELL LYSIS AND PCR WITHIN THE SAME REACTION CHAMBER - A method for amplification of a target DNA, comprising the steps of (i) transferring a liquid with a first volume comprising at least one or more living cells into a vessel (ii) adding to said vessel a PCR reaction buffer with a second volume, whereas said second volume is at least 2× as large as said first volume (iii) lysing said at least one or more living cells within said vessel by means of incubation for at least 1 Minute at at least 90° C., and (iv) amplifying said target by means of a polymerase chain reaction without performance of an intermediate purification step. | 08-08-2013 |
20130197335 | DEVICE AND METHOD FOR POSITIONING A BODY PART FOR FLUID ANALYSIS - A device and a method are disclosed for positioning a body part ( | 08-01-2013 |
20130196447 | MICROFLUIDIC ELEMENT FOR THOROUGHLY MIXING A LIQUID WITH A REAGENT - A microfluidic element for thoroughly mixing a liquid with a reagent used for the analysis of the liquid for an analyte contained therein and a method thereof are disclosed. The microfluidic element has a substrate and a channel structure. The channel structure includes an elongate mixing channel and an output channel. The mixing channel has an inlet opening and an outlet opening, and is implemented to mix the reagent contained therein with the liquid flowing through the inlet opening into the mixing channel. The outlet opening of the mixing channel is in fluid communication to the output channel. The outlet opening is positioned closer to the middle of the length of the mixing channel than the inlet opening. | 08-01-2013 |
20130195720 | SAMPLE RACK HANDLING UNIT - A sample rack handling unit comprising an onload section for loading sample racks holding a sample container is presented. The onload section comprises an onload edge and a receiving area with an onload rail longitudinally on the receiving area parallel to the onload edge. The onload rail engages a recess on the rack bottom such that the rack longitudinally slides on the receiving area along the onload rail when the rack is engaged. The onload rail has a base portion and a protrusion extending from the base portion. The protrusion faces the onload edge and the base portion comprises an inclined onload rail side opposite the onload edge such that the recess engages the onload rail when the rack is loaded on the receiving area from the onload edge transversely to the onload rail and the recess disengages the onload rail by sliding the rack towards the onload edge. | 08-01-2013 |
20130190579 | METHOD AND APPARATUS FOR LIGHTED TEST STRIP - A test strip with a sample chamber is secured to a meter. The sample chamber in the portion of the test strip that extends out of the meter is illuminated by transmitting light from a light source inside the meter internally through the test strip towards the sample chamber. By way of analogy, the test strip acts in a fashion similar to a fiber optic cable or optical wave guide by transmitting the light from the meter to the remotely located sample chamber that extends outside the meter. The user is then able to easily see the sample chamber of the test strip in dark conditions so that the user is able to readily align the sample chamber with the drop of fluid on the skin as well as view the sample chamber in order to ensure proper filling. The light also illuminates a test strip slot into which the test strip is inserted. | 07-25-2013 |
20130189798 | LUMINESCENCE METHOD OF DETECTING AN ANALYTE IN A LIQUID SAMPLE AND ANALYSIS SYSTEM - The present disclosure relates to a luminescence method of detecting an analyte in a liquid sample comprising marking the analyte with a marker capable of effecting luminescence upon application of excitation energy, wherein reference data descriptive of the luminescence decay is stored in an electronic memory; applying the excitation energy for causing the luminescence; time-resolved measuring of the luminescence over a period of time for acquisition of a measurement signal; reading the reference data from the electronic memory; comparing the measurement signal with the luminescence decay described by the reference data; generating an output signal indicative of the presence of the analyte in the liquid sample using the measurement signal; in case of a mismatch of the measurement signal and the luminescence decay described by the reference data, generating an error signal. | 07-25-2013 |
20130185396 | DYNAMIC COMMUNICATION STACK - A method of facilitating communication between a resource and a computer is described. The computer employs a software application that allows the computer to communicate with the resource. The resource may comprise a medical device such as a blood glucose meter or an insulin pump. In order to facilitate communication between the computer and the resource, the software constructs a communication protocol particular to the type of resource connected to the computer. The stack comprising the communication protocol allows the computer to communicate with the resource. Once the resource and computer cease communication, the stack may be removed from the memory of the computer. | 07-18-2013 |
20130184996 | DEVICE AND METHOD FOR INSULIN DOSING - A device and method of providing instruction to a patient regarding the dosing of insulin is provided. | 07-18-2013 |
20130183212 | BENT MICROSTRUCTURES FOR SAMPLING, TRANSPORTING OR DISPENSING A FLUID MEDIA - A device for sampling, transporting and/or disposal of fluid media in the nI and μl-range comprises a substrate with an open or closed capillary-like groove or channel respectively, the substrate with the open or closed groove or capillary respectively is bent or arcuated at least at one location. The substrate comprises at least one end into which the open or closed capillary-like groove or channel respectively is extended, which end is shaped according to its application or use as e.g. needle-like, straight-lined cut, tip-like, at least most half circle-shape, rounded, etc. | 07-18-2013 |
20130179186 | SYSTEM AND METHOD FOR DATABASE SYNCHRONIZATION FOR MEDICAL RECORDS - A system and method for performing database synchronization between a first database of a first device and a second database of a second device is disclosed. The first database stores medical records having non-time based counter values associated thereto. The second database stores medical records having timestamps associated thereto. The first device includes a first database synchronization module that maintains a last timestamp indicating a last medical record that was received from the second device. The first database synchronization module transmits, to the second device, a request for synchronization and the last timestamp. The second device includes a second database synchronization module that maintains a last counter value indicative of a last medical record that was received from the first device, and that transmits, to the first device, a second request for synchronization and the last counter value. | 07-11-2013 |
20130173968 | DYNAMIC LINK LIBRARY INTEGRITY CHECKING FOR HANDHELD MEDICAL DEVICES - A method of checking the integrity of a dynamic link library (DLL) file called by an application being executed on a handheld medical device is described. The method includes loading a DLL from a read only memory (ROM) to a random access memory (RAM) beginning at a fixed location in the RAM. The DLL includes a first routine for performing a safety critical function of the handheld medical device and a second routine for performing a cyclical redundancy check (CRC) once the DLL is loaded to the RAM. The method includes selectively executing the first routine from the RAM. The method includes selectively executing the second routine from the RAM including: calculating a check value based on the DLL; comparing the check value with a predetermined check value; and indicating that an error is present when the check value is different than the predetermined check value. | 07-04-2013 |
20130173566 | STRUCTURED TEST ADHERENCE MANAGEMENT FOR MANUAL DATA ENTRY SYSTEMS - A computer-implemented method is provided for managing manual entries of blood glucose measures for a patient in relation to a structured collection procedure managed by a portable computing device. The method includes: managing a structured collection procedure for a user of the computing device, where the structured collection procedure specifies one or more collection events for obtaining blood glucose measures for a patient; receiving a data entry for a blood glucose measure from the user of the computing device; evaluating the data entry in relation to the structured collection procedure using a membership rule set, where the membership rule set defines rules for associating data entries with structured collection procedures; and inputting the data entry into a logbook residing in a data store on the computing device. Depending upon the evaluation, the data entry may be input with or without an association to the structured collection procedure. | 07-04-2013 |
20130173473 | DATA SYCHRONIZATION SYSTEMS AND METHODS - A method performed by a medical device includes: receiving electronic medical data from one or more input devices; storing the medical data in a first datastore associated with the medical device; receiving a non-expiring, cryptographic token from a server in response to a transmission of account data, the non-expiring, cryptographic token associated with the medical device for synchronizing the medical data stored in the first datastore with the medical data stored in the second datastore that is associated with the server; transmitting the non-expiring, cryptographic token to the server for authentication by the server; selectively transmitting at least a portion of the medical data stored in the first datastore to the server for storage in the second datastore; selectively receiving at least a portion of the medical data stored in the second datastore from the server; and selectively storing the medical data received from the server in the first datastore. | 07-04-2013 |
20130173307 | INTERFACE FOR AN ELECTRONIC MEDICAL RECORD SYSTEM - An interface for an electronic medical record (EMR) system is configured to receive messages and documents having a message data format and a document data format respectively, transmitted to EMR system in accordance with a first and second device healthcare interoperability standard. The interface is further configured to determine whether a given message or document pertains to blood glucose measures and to generate records in a custom format of the EMR system. The interface is further configured to parse the messages and documents for a structure collection procedure from a comment field in the given messages and documents and to map the structured collection procedure data to applicable data fields in a corresponding record of the EM system. | 07-04-2013 |
20130172710 | Handheld Diabetes Manager With A Personal Data Module - A handheld diabetes manager communicates with an external insulin pump and includes a port for blood glucose measurement, a blood glucose measurement module, a communications module that selectively communicates wirelessly with the insulin pump, and a user interface module. The user interface module communicates with the blood glucose measurement module and the communications module and operates to provide a graphical user interface on a display of the diabetes manager. The graphical user interface includes a personal data menu screen from which a logbook option can be selected to display a logbook screen, and a trend graph option that can be selected to display a trend graph screen. The logbook screen displays a plurality of time data records. Each time data record includes blood glucose data, bolus insulin data, and carbohydrate data for a corresponding time, and a plurality of data icons indicating corresponding events. | 07-04-2013 |
20130172709 | Handheld Diabetes Manager With A Flight Mode - A handheld diabetes manager has a flight mode that cooperatively interacts with an external medical device and includes a port configured to receive a test strip for blood glucose measurement, a blood glucose measurement module operable with the test strip, a communications module and a user interface module. The communications module selectively communicates wirelessly with an external medical device. The user interface module communicates with the blood glucose measurement module and the communications module and operates to provide a graphical user interface on a display of the diabetes manager. The graphical user interface includes a screen with a flight mode option. When the flight mode option is enabled and the external medical device is paired and currently communicating with the diabetes manager, the user interface module interacts with the communication module to send a command to the external medical device to turn off wireless communication of the external medical device. | 07-04-2013 |
20130172708 | Handheld Diabetes Manager With A User Interface For Displaying A Status Of An External Medical Device - A handheld diabetes manager has a graphical user interface for displaying status of an external medical device and includes a port configured to receive a test strip and a blood glucose measurement module. The diabetes manager includes a communications module that selectively communicates via a wireless data link with an external medical device to receive status data pertaining to the operation of the external medical device, and a user interface module in data communication with the blood glucose measurement module and the communications module. The graphical user interface includes a status screen that presents data pertaining to a glucose measure determined by the blood glucose measurement module concurrently with the status data received from the external medical device, such that the status data of the external medical device is presented on the status screen only when the communication module is in data communication with the external medical device. | 07-04-2013 |
20130172707 | GRAPHICAL USER INTERFACE PERTAINING TO A BOLUS CALCULATOR RESIDING ON A HANDHELD DIABETES MANAGEMENT DEVICE - A handheld diabetes manager is presented with an improved graphical user interface for a bolus calculator. The bolus calculator is configured to receive blood glucose measurements from a blood glucose measurement module and operates, in response to an input, to compute an insulin recommendation for a patient based in part on the blood glucose measurements. The graphical user interface for the bolus calculator includes a health adjustment screen that enables a user to input a value for health events associated with the insulin recommendation, where the input value represents a cumulative effect of the health events on insulin of the patient and the health adjustment screen presents a different icon for each of the health events associated with the insulin recommendation. | 07-04-2013 |
20130172706 | USER INTERFACE FEATURES FOR A DIABETES MANAGEMENT APPLICATION - A method is provided for contextualizing manual entries of blood glucose measures for a patient into a patient log of a portable computing device. The method includes: administering a structured collection procedure, where the structured collection procedure specifies two or more collection actions for obtaining blood glucose measures from a patient; generating a reminder notification for a given collection action of the structured collection procedure, where the given collection action is associated with a given event of patient; and displaying a data entry interface upon receipt of an acceptance input from a user in response to the reminder notification, where the data entry interface includes a first input for a blood glucose measure and a second input for an event associated with the blood glucose measure, such that value for the second input is defaulted to the given event from the reminder notification. | 07-04-2013 |
20130172688 | DIABETES MANAGEMENT APPLICATION FOR MOBILE PHONE - A mobile device for managing diabetes care of a patent is disclosed. The device has a data entry interface configured to receive glucose measures for the patient and store the glucose measures in a patient log residing on the device. The device has a selection module that operates to selectively analyze the glucose measure in the patient log and select a given structural collection procedure from a plurality of standardized collection procedures. | 07-04-2013 |
20130171938 | HANDHELD DIABETES MANAGER WITH AUTOMATED DISCONNECT FEATURE - A computer-implemented method is provided for a handheld diabetes-management device to establish a data connection with a Continua manager. The method includes: receiving a request to establish a new data connection with a computing device, where the computing device is physically separated from the diabetes-management device and operates as a manager in accordance with IEEE standard 11073; determining whether the diabetes-management device has an existing data connection with a medical device that is physically separated from the diabetes-management device; terminating the existing data connection with the medical device in response to the determination that the diabetes-management device has an existing connection with the medical device; and establishing a new data connection with the computing device in accordance with IEEE standard 11073. | 07-04-2013 |
20130169436 | REMINDER MANAGEMENT FOR MANUAL ENTRY DIABETES APPLICATION - A method is provided for managing manual entries of blood glucose measures in relation to a structured collection procedure administered by a portable computing device. The method includes: receiving an expected time for an event associated with a structured collection procedure, defining an acceptance window for a given collection action associated with the structured collection procedure and creating a reminder for the given collection action in a persistent data store, where the reminder specifies a time at which to initiate a reminder. Upon receiving a data entry of a blood glucose measure, the reminder event is purged from the data store when the data entry is received prior to the time at which to initiate the reminder. Conversely, a reminder notification is presented to the user when the data entry has not been received in advance of the time at which to initiate the reminder. | 07-04-2013 |
20130167249 | CUSTOMER SUPPORT ACCOUNT WITH RESTRICTED PATIENT DATA ACCESS - A method for accessing a user's account by customer support without viewing the user's private data includes receiving, in an application module communicating with a web service, a request for authentication by a support person using a linked user-support login name. The method includes authenticating the user, authenticating the support person and retrieving a current session of the user as viewed by the user on an electronic screen of a processing device of the user. The method further includes dynamically redacting private data of the user from the user session to create a redacted user session, and delivering the redacted user session for display in an electronic screen of a processing device of the support person. | 06-27-2013 |
20130167245 | CUSTOMER ERROR SCREEN CAPTURE - A method for capturing a user's view of an electronic screen having an error message in a health management application without showing private information of the user includes receiving an error message from a web service responding to a request for a web page by the user. The method includes receiving an electronic file of the web page with the error message, redacting private information of the user from the electronic file to create a redacted electronic file, and storing the redacted electronic file in a support log module. | 06-27-2013 |
20130164718 | HANDHELD DIABETES MANAGER WHICH SUPPORTS PREPLANNED MEALS FOR IMPROVED THERAPY - A handheld diabetes management device is provided which supports preselected meals for improved therapy. The diabetes management device includes: a food database that stores nutritional information for a plurality of food items; a meal selection module that enables a user to preplan meals for a diabetic patient using the food database; and a meal planner module that facilitates use of the preplanned meals to improve therapy for the patient. The diabetes management device further includes an insulin management module that forecasts amounts of insulin needed by a patient over a period of time. | 06-27-2013 |
20130160530 | METHOD AND SYSTEM FOR DISCRIMINATING BULK LIQUID FROM FOAM AND RESIDUALS OF THE BULK LIQUID - A method and an automated system for discriminating bulk liquid from foam and/or residuals of the bulk liquid of a sample contained in a sample vessel are presented. A probe having an electric capacitance is provided and moved into the sample. Consecutive steps of charging and at least partially discharging the probe to generate a discharging current is repeatedly performed. A quantity indicative of the discharging current for the consecutive steps of charging and at least partially discharging the probe is measured. The quantity is analyzed to determine an electric resistance (R | 06-27-2013 |
20130158373 | SYSTEM FOR WITHDRAWING SMALL AMOUNTS OF BODY FLUID - A system is provided for withdrawing small amounts of body fluid from an animal or human. The system includes a holder and a disposable lancing unit attached to the holder. The lancing unit also includes an open capillary channel for transporting the body fluid and piercing the skin. | 06-20-2013 |