QUEENSLAND UNIVERSITY OF TECHNOLOGY Patent applications |
Patent application number | Title | Published |
20150347918 | FUTURE EVENT PREDICTION USING AUGMENTED CONDITIONAL RANDOM FIELD - Systems and methods are disclosed for a future event prediction. Embodiments include capturing spatiotemporal data pertaining to activities, wherein the activities include a plurality of events, and employing an augmented-hidden-conditional-random-field (a-HCRF) predictor to generate a future event prediction based on a parameter-vector input, hidden states, and the spatiotemporal data. Methods therein utilize a graph including a first node associated with random variables corresponding to a future event state, a second node associated with random variables corresponding to spatiotemporal input data, a first group of nodes, each node therein associated with random variables corresponding to a subset of the spatiotemporal input data, a second group of nodes, each node therein associated with random variables corresponding to a hidden-state; wherein the edges connect the first node with the second node, the first node with the second group of nodes, and the first group of nodes with the second group of nodes. | 12-03-2015 |
20150297128 | APPARATUS AND METHOD FOR KNEE FLEXOR ASSESSMENT - An apparatus for use in assessing strength of at least one knee flexor muscle of a subject, the apparatus including a support, two securing members, each securing member securing a respective lower leg of the subject in a position that in use is substantially fixed relative to the support and at least one sensor, which in use senses a force indicative of the strength of the at least one knee flexor muscle in at least one leg of the subject while the subject performs an eccentric contraction of the at least one knee flexor muscle. | 10-22-2015 |
20150036102 | SLOWING MYOPIA PROGRESSION AND/OR THE TREATMENT OR PREVENTION OF MYOPIA OR A DISEASE OR CONDITION ASSOCIATED WITH MYOPIA - The invention provides an ophthalmic lens comprising one or more oblique prismatic component, wherein the lens slows myopia progression and/or treats or prevents myopia or a disease or condition associated with myopia. The one or more oblique prismatic components may be base-down or base-down and base-in or base up and base-in. The one or more oblique prismatic components may be central and/or in a distance and/or near zone of the ophthalmic lens. The invention also provides an ophthalmic lens comprising a central base-down prism in a distance zone wherein the lens slows myopia progression and/or treats or prevents myopia or a disease or condition associated with myopia. Also provided is an optical device comprising one or more ophthalmic lenses and a method of slowing myopia progression and/or treating or preventing myopia or a disease or condition associated with myopia including using one or more ophthalmic lenses. | 02-05-2015 |
20140366220 | Compositions and Methods for Increased Expression in Sugar Cane - A sugar cane plant cell comprising a recombinant nucleic acid molecule is provided, the recombinant nucleic acid molecule comprising a nucleotide sequence of interest, a promoter and the nucleotide sequence of SEQ ID NO:1, wherein the promoter is downstream of and in operative association with the nucleotide sequence of SEQ ID NO:1 and upstream of and in operative association with the nucleotide sequence of interest, and the nucleotide sequence of interest is expressed at a level at least about 6 times greater than the level of expression of said nucleotide sequence of interest in a control. Additionally, a method of increasing the expression of a nucleotide sequence of interest in a sugar cane plant cell using the recombinant nucleic acid molecule of the invention is provided. | 12-11-2014 |
20140093920 | METHODS FOR TREATING LIGNOCELLULOSIC MATERIALS - The present invention provides compositions and methods for the pretreatment of lignocellulosic material. The present invention further provides for pretreated lignocellulosic material that can be used to produce products, such as fermentable sugars. | 04-03-2014 |
20140093918 | METHODS FOR CONVERTING LIGNOCELLULOSIC MATERIALS TO USEFUL PRODUCTS - The present invention provides compositions and methods for the pretreatment of lignocellulosic material. The present invention further provides for pretreated lignocellulosic material that can be used to produce useful products, such as fermentable sugars. | 04-03-2014 |
20140093917 | METHODS FOR CONVERTING LIGNOCELLULOSIC MATERIAL TO USEFUL PRODUCTS - The present invention provides compositions and methods for the pretreatment of lignocellulosic material. The present invention further provides for pretreated lignocellulosic material that can be used to produce useful products, such as fermentable sugars. | 04-03-2014 |
20140045749 | GROWTH FACTOR COMPLEX - A method is provided for treating a disease or condition characterized by aberrant epithelial cell proliferation and/or migration. One step of the method can include administering to a mammal an agent which disrupts an isolated protein complex including: insulin-like growth factor I (IGF-I); an insulin-like growth factor binding protein (IGFBP) selected from IGFBP-3 and IGFBP-5; and vitronectin; or which prevents formation of the isolated protein complex, to thereby treat the disease or condition in the mammal. The agent is selected from the group consisting a polypeptide that is distinguished from IGF-II by substitution of at least one amino acid residue, wherein the polypeptide disrupts the isolated protein complex. | 02-13-2014 |
20140018211 | SWIM TRAINING APPARATUS - A swim training apparatus for training a user during swimming, the apparatus including, an at least semi-rigid body, an attachment mechanism to allow the body to be worn by the user so that at least part of the body contacts the user's torso to thereby provide at least one of resistance training for improving at least one of strength and stability of the user, and posture training for guiding user posture. | 01-16-2014 |
20130291233 | Methods and Compositions for Modified Ethanol Inducible Promoter Systems - The present invention provides nucleic acid molecules comprising one or more nucleotide sequences selected from the group consisting of the nucleotide sequence of SEQ ID NO:1, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, SEQ ID NO:6, SEQ ID NO:7, SEQ ID NO:8, and/or SEQ ID NO:10 that can be operably linked to a promoter, thereby making the promoter inducible by a chemical compound that can induce the expression of the alcohol dehydrogenase system of | 10-31-2013 |
20130243843 | Vitronectin:Keratinocyte Growth Factor Chimeras - Isolated protein complexes are provided comprising keratinocyte growth factor and vitronectin, or at least domains thereof that enable binding to and activation of both a keratinocyte growth factor receptor and an integrin receptor for vitronectin. These protein complexes include synthetic proteins where the keratinocyte growth factor and vitronectin sequences are joined by a linker sequence. In particular forms, vitronectin sequences do not include a C-terminal heparin binding domain. Also provided are uses of these protein complexes for stimulating or inducing cell migration and/or proliferation in wound healing, tissue engineering, cosmetic and therapeutic treatments such as skin replacement, skin replenishment and treatment of burns where epithelial cell migration is required. In other embodiments, the invention provides inhibition of cancer cell metastasis, particularly in relation to breast cancer. | 09-19-2013 |
20130004543 | FIBRONECTIN: GROWTH FACTOR CHIMERAS - Isolated protein complexes are provided comprising growth factors such as IGF-I, IGF-II, EGF, bFGF, or KGF and fibronectin, or at least domains thereof that enable binding to and activation of both a growth factor receptor, and an integrin receptor-binding domain of fibronectin. These protein complexes include synthetic proteins where the growth factor and fibronectin sequences are joined by a linker sequence. Also provided are uses of these protein complexes for stimulating or inducing cell migration and/or proliferation in wound healing, tissue engineering, cosmetic and therapeutic treatments such as skin replacement, skin replenishment and treatment of burns where epithelial cell migration is required. In other embodiments, the invention provides inhibition of cancer cell metastasis, particularly in relation to breast cancer. | 01-03-2013 |
20120219536 | PURINE-TARGETED DIAGNOSIS AND THERAPY OF WOUNDS - Methods of treating a wound, an ulcer and/or a burn responsive to inhibition of xanthine oxidoreductase to thereby reduce uric acid in an animal are provided wherein the methods include topical administration of a therapeutic agent effective for treatment of the wound, the ulcer and/or the burn wherein the therapeutic agent inhibits xanthine oxidoreductase to thereby reduce uric acid in the wound, ulcer and/or burn. Also provided are methods and kits for determining the severity of a wound, a burn and/or an ulcer including the step of detecting one or more of (i) a level of uric acid; (ii) a level of one or more uric acid precursors; and (iii) a presence, or absence of or level of xanthine oxidoreductase. | 08-30-2012 |
20110269716 | ANTIOXIDANT COMPOUNDS AND METHODS OF THEIR USE - The invention relates to antioxidant substituted isoindoline nitroxide compounds and their use in methods of treating or preventing diseases or disorders related to oxidative stress, methods of reducing oxidative stress and methods of protecting a subject from oxidative stress upon exposure to ionising radiation. Pharmaceutical compositions comprising the antioxidant compounds are also described. | 11-03-2011 |
20110172163 | Novel Protease Inhibitors - The invention relates to KLK protease inhibitors. In particular, the invention is directed to KLK4 protease inhibitors and their uses in the treatment of a cancer, such as prostate cancer. | 07-14-2011 |
20110119782 | CONSTRUCT CAPABLE OF RELEASE IN CLOSED CIRCULAR FORM FROM A LARGER NUCLEOTIDE SEQUENCE PERMITTING SITE SPECIFIC EXPRESSION AND/OR DEVELOPMENTALLY REGULATED EXPRESSION OF SELECTED GENETIC SEQUENCES - The present invention relates generally to constructs and in particular genetic constructs comprising polynucleotide sequences capable of release in covalently closed, circular form from a larger nucleotide sequence such as, but not limited to, a genome of a eukaryotic cell. Preferably, once released, a polynucleotide sequence is reconstituted in a form which permits expression of the polynucleotide sequence. In one embodiment, the reconstituted polynucleotide sequence comprises a coding sequence with all or part of an extraneous nucleotide such as, but not limited to, an intronic sequence or other splice signal inserted therein. Expression and in particular transcription of the coding sequence involves splicing out the extraneous sequence. The release and circularization is generally in response to a stimulus such as a protein-mediated stimulus. More particularly, the protein is a viral or prokaryotic or eukaryotic derived protein or developmentally and/or tissue specific regulated protein. | 05-19-2011 |
20100281566 | TRANSCRIPTIONAL CONTROL ELEMENT, CHIMERIC CONSRUCTS AND USES THEREFOR - This invention discloses a constitutive promoter for expression of foreign or endogenous coding sequences in plants, including dicotyledonous and monocotyledonous plants. The invention also discloses a chimeric nucleic acid construct comprising the promoter of the invention operably linked to a foreign or endogenous polynucleotide that codes for a protein of interest or a transcript capable of modulating expression of a target gene. The invention further discloses transformed plant cells, as well as differentiated plants and plant parts, containing the construct. Methods for diagnosis and treatment of viral infections, especially badnaviral infections, are also disclosed. | 11-04-2010 |
20100276955 | TREATMENT OF RAILWAY WHEELS - A method of treating a steel railway wheels to form a required distribution of compressive residual stress in the rim. In general terms the wheel heated and then quenched from the plate towards the rim. The wheel is first heated to form austenite throughout the plate and rim portions. The wheel is then cooled to form bainite/martensite in the plate portion. The wheel is cooled to form bainite/martensite in an inner portion of the rim. The wheel is cooled to form bainite/martensite in an outer portion of the rim. | 11-04-2010 |
20100172860 | WOUND REPAIR COMPOSITION AND METHOD - The invention provides a dressing composition comprising a bisphosphonate matrix metalloproteinase (MMP) inhibitor covalently bound to a polymer wherein, when the dressing is contacted with a wound, substantially all of the bisphosphonate remains with the dressing composition and is unable to enter the wound tissue. The invention also provides for a method of treatment of a wound by contacting a dressing composition comprising a covalently bound MMP inhibitor with the wound fluid to thereby selectively inhibit one or more MMP's in the wound fluid without inhibiting those in the wound tissue. | 07-08-2010 |
20090311303 | BIODEGRADABLE IMPLANTS FOR BONE FUSION AND COMPOSITIONS THEREFOR - A biodegradable copolymer network, which is particularly suited for use in applications such as interbody implants for bone fusion, is provided. The biodegradable copolymer network of the present invention is biodegradable yet provides sufficient mechanical strength for use in procedures such as spinal fusion. Also provided are methods of producing said biodegradable copolymer network, methods of delivery of biologically active substances, implants comprising said biodegradable copolymer network and methods of administering bioactive and in particular, osteoinductive, substances. | 12-17-2009 |
20090291432 | Genetic profiles associated with the 957C>T polymorphism in the DRD2 gene - The present invention relates to a method for profiling an individual or group of individuals with respect to a neurological, psychiatric or psychological condition, phenotype or state, including a sub-threshold neurological, psychiatric or psychological condition, phenotype or state. More particularly, the present invention identifies a genetic profile associated with the 957C>T polymorphysm within the dopamine receptor D2 (DRD2), indicating a predisposition to schizophrenia and other neurological diseases. | 11-26-2009 |
20090141235 | Control of Myopia Using Contact Lenses - Devices and methods for controlling myopia are provided. The devices and methods relate to the inventors discovery of the relationship between near work, the forces applied to the eye by the eyelids and myopia. The devices include a contact lens comprising a region that disperses force applied to the eye by an eyelid. The devices also include a device designed by measuring first wavefront aberrations of an eye before pre-near work and measuring second measured wavefront aberrations of the eye post-near work. The methods include a method for controlling myopia including identifying optical changes associated with near work and correcting the optical changes with an optical device. | 06-04-2009 |
20090076742 | ESTIMATION OF WHEEL RAIL INTERACTION FORCES - A method of estimating contact forces between the wheels of a railway wagon and a rail track, for use in determining information such as the likelihood of derailment. Accelerations of the body of the wagon are measured using motion sensors located at suitable points on the body. Forces on the side frames of the wagon are calculated based on the accelerations of the body and predetermined parameters of the body. Forces on the wheels of the wagon are calculated based on the accelerations of the body and predetermined parameters of the body. The contact forces between the wheels and the rails are then calculated based on the forces calculated for the side frames and the wheels. The calculations are carried out using an inverse model of the wagon system. Equipment which implements the method is also described. | 03-19-2009 |
20090075827 | DIAGNOSTIC METHODS AND AGENTS - The present invention relates generally to a method and agents for profiling or stratifying an individual or group of individuals with respect to a neurological, psychiatric or psychological condition, phenotype or state, including a sub-threshold neurological, psychiatric or psychological condition, phenotype or state. More particularly, the present invention utilizes genetic means to profile or stratify individuals with respect to a neurological, psychiatric or psychological condition, phenotype or state. The present invention enables the identification of individuals at risk of these disorders thus affording the opportunity for early intervention. In addition, the subject invention allows the prediction of drug or other treatment response and adverse reactions. | 03-19-2009 |
20090028891 | Chlamydia Antigens and Uses Thereof - The invention provides protein and nucleic acid sequences of | 01-29-2009 |
20080299067 | Functionalised Siloxanes for Scar Tissue Treatment - A novel composition for use in treating a wound, burn or other skin condition comprises one or more compounds of formula (I), wherein: m = 0-6, n = 6-100, Q, R and R′ may be independently selected from, C1-5 alkyl, OU, UOCH2CH3, CH2CH3, UOCH3, OH, O(CH2)y(OU)yCH3, (OCH2CH2)yOU, (OCH2CH2)yOH, UOH, UOU′, UCO2U′, CO2U, UCO2COU, CO2H, UCO2H, COX, UCOX, UCO2 R′, CO2COU, Aryl, ArylU, ArylUU, ArylUU′U″, NH2, UNH2, NHU, NUU′, NO2, UNO2, UCONH2, CONH2, UCONHU′, CONHU, UCONU′U″, CONU′U″, halogen, PO4H3, PO4H3-z, PO4H3-zU (z = 0, 1, 2 or 3), PU3, P U′U″U′″SH, SO2 and SO3H; wherein U, U′, U″ and U′″ may be independently selected from any alkyl, alkenyl or alkynyl group where the number of carbon atoms is between 1 and 31; wherein X=halogen; wherein y=1-100; provided that Q, R and R′ can not all be C1 alkyl; and wherein the compound of formula (I) is present in an amount of at least 1% of the composition. | 12-04-2008 |