| PURDUE RESEARCH FOUNDATION Patent applications |
| Patent application number | Title | Published |
|---|
| 20160141133 | CAPACITIVE MICROELECTROMECHANICAL SWITCHES WITH DYNAMIC SOFT-LANDING - A microelectromechanical system (MEMS)-based electrical switch. The electrical switch includes a moveable electrode, a dielectric layer positioned adjacent the moveable electrode on a first side of the dielectric layer and spaced apart from the moveable electrode when the moveable electrode is in an inactivated position and in contact with the moveable electrode when the moveable electrode is in an activated position, and a substrate attached to the dielectric layer on a second side opposite to the first side, the moveable electrode is configured to brake prior to coming in contact with the dielectric layer when the moveable electrode is switched between the inactivated state and the activated state. | 05-19-2016 |
| 20160133990 | SOLID-STATE ELECTROLYTES AND BATTERIES MADE THEREFROM, AND METHODS OF MAKING SOLID-STATE ELECTROLYTES - Method of making solid-state electrolyte with composition formula Li | 05-12-2016 |
| 20160129163 | OSTEOBLAST STIMULATING ORTHOPEDIC IMPLANT - Nanomaterials for neural and orthopedic prostheses are disclosed. Composite carbon nanofibers enhance neuronal growth and minimize glial scar tissue formation. Methods and compositions to promote neuronal growth and minimize scar tissue formation during prolonged monitoring and treatment of neural tissue are disclosed. Composite polyurethane carbon nanofiber is a suitable material for neural implant. Composite carbon nanomaterials decrease adhesion of astrocytes and fibroblasts. | 05-12-2016 |
| 20160116985 | UNIVERSAL TRANSLATOR FOR RECOGNIZING NONSTANDARD GESTURES - A system and method to project gesture patterns of gestural behavior designed for existing gesture systems to those exhibited by persons with limited upper limb mobility, such as quadriplegics due to spinal cord injury (SCI), hemiplegics due to stroke, and persons with other types of disabilities. The system acquires a plurality of gesture instances from a gesture sensor, maps the plurality of gesture instances, determines a union amongst the plurality of gesture instances to thereby acquire a plurality of trajectory points, encodes the plurality of trajectory points into a feature vector, extracts a plurality of features from the feature vector, normalizes the plurality of features, determines at least one transform function from the plurality of features, and generates constrained gestures from the at least one transform function to form at least one gesture set. | 04-28-2016 |
| 20160114142 | SMART CAPSULE WITH GI-TRACT-LOCATION-SPECIFIC PAYLOAD RELEASE - A remotely activatable capsule. The capsule includes a housing that can be swallowed by a subject, an electrical energy reservoir having a first terminal and a second terminal positioned in the housing, a remotely activatable switch positioned in the housing and configured to be remotely activated, and a function-specific mechanism positioned in the housing and electrically coupled to the remotely activatable switch and to the electrical energy reservoir and configured to perform a function when the remotely activatable switch is activated. | 04-28-2016 |
| 20160107948 | MECHANICALLY ACTIVATED METAL FUELS FOR ENERGETIC MATERIAL APPLICATIONS - The invention provides mechanically activated metal fuels for energetic material applications. An exemplary embodiment involves mechanically treating micrometer-sized particles of at least one metal with particles of at least one fluorocarbon to form composite particles containing the at least one metal and the at least one fluorocarbon. | 04-21-2016 |
| 20160105153 | Band-Reconfigurable and Load-Adaptive Power Amplifier - A tunable amplifier includes continuous tunability for both frequency and power levels. The tunable amplifier includes a combination of a tunable series resonator and a multi-stage LC network as the output matching network. The tunable amplifier incorporates a variable diode varactor with high breakdown voltage and high tuning range into a tunable resonator. The tunable resonator is connected to a fixed output matching network to enable a wide range of operating frequencies. The tunable amplifier enables high power, high efficiency, broadband and load-modulated power amplification, which is greatly desired for next-generation wireless communication systems and other high-frequency applications. | 04-14-2016 |
| 20160102392 | METHODS OF MAKING AND TREATING COPPER-BASED ALLOY COMPOSITIONS AND PRODUCTS FORMED THEREFROM - A ternary alloy wherein copper, manganese, and a ternary element are melted together and cast into an article and the article is subjected to an age-hardening treatment. A process for producing an age-hardened copper-manganese-nickel alloy, the process including melting a composition comprising copper, manganese and nickel; pouring the molten composition comprising copper, manganese, and nickel to form a casting with a composition comprising copper, manganese, and nickel, and aging the casting so produced. An article containing copper, manganese, and a ternary element, in a cast form and the cast form has subsequently undergone age-hardening treatment. A ternary alloy comprising copper, manganese, and a ternary element melted together and solidified into a casting, wherein the microstructure of the casting produced shows substantially low microporosity attributable to dendritic solidification. | 04-14-2016 |
| 20160101984 | PREPARATION OF AMINE-BORANES, INCLUDING AMMONIA BORANE - Disclosed herein is a method for preparing amine-boranes. | 04-14-2016 |
| 20160084740 | ENGINEERED DETECTION SWAB - A novel, advanced polymeric swab is disclosed herein. The swabs have a surface texture that allows for independent motion between microscale regions, are reusable with no loss of accuracy or efficiency, and are fabricated from optoelectronically-active elements to minimize static charging during repeated use. | 03-24-2016 |
| 20160077403 | OPTO-ELECTRIC FREQUENCY COMB GENERATOR - An optical comb generator, having a light input port configured to receive a continuous wave light from a laser source and a plurality of phase modulators coupled to the light input port. At least one intensity modulator is coupled to the plurality of the phase modulators, along with a plurality of phase shifters. The phase shifters are coupled to a corresponding phase modulator. A radio frequency (RF) clock is coupled to the phase modulators and the intensity modulator, and configured to provide synchronous clock input to the phase modulators and the intensity modulator. The comb generator may also incorporate an RF switch disposed between the RF clock and the phase shifters associated with a phase modulator, so that the RF switch enables tuning each corresponding phase shifter to thereby provide a tunable optical comb. | 03-17-2016 |
| 20160071412 | METHODS AND SYSTEMS FOR REAL-TIME ADVANCED CONGESTION IDENTIFICATION AND WARNING - The present disclosure relates to a system and method for locating slow or stopped vehicles on a roadway and alerting drivers approaching the back of a queue, and in particular to intelligent transportation systems and traffic management. | 03-10-2016 |
| 20160070093 | Deconvolution By Digital Filtering From Linear Discriminate Analysis - A quantitative optical microscopy arrangement is described. Specifically, a digital filter derived from linear discriminant analysis is described for recovering impulse responses in applications that may include photon counting from a high speed photodetector and applied to remove ringing distortions from impedance mismatch in multiphoton fluorescence microscopy. Training of the digital filter is achieved by defining temporally coincident and non-coincident transients and identifying the projection within filter-space that best separates the two classes. The training allows rapid data analysis by digital filtering. The LDA filter is also capable of recovering deconvolved impulses for single photon counting from highly distorted ringing waveforms from an impedance mismatched photomultiplier tube. The LDA filter is also successful in removing these ringing distortions from two-photon excited fluorescence micrographs and may extend the dynamic range of photon counting by about three orders of magnitude through minimization of detector paralysis. | 03-10-2016 |
| 20160068828 | LIQUEFIED CELLULOSIC BIOMASS FOR ENZYME PRODUCTION - Methods for enhancing production of a cellulose component are disclosed herein. | 03-10-2016 |
| 20160068562 | Raman Tag - The present invention provides novel Raman tags for exploring membrane interactions in cells. The tags comprise a phenyl diyne probe where in the dyine is capped with the phenyl group. Methods for using the tags are also provided. | 03-10-2016 |
| 20160068405 | SOLUTION BASED SYNTHESIS OF COPPER-ARSENIC-CHALCOGEN NANOPARTICLES - Disclosed herein are synthesis methods and uses of nanoparticles containing copper, arsenic, and chalcogen, in particular their use for making thin films useful for electronics, photovoltaics, and solar energy conversion devices. | 03-10-2016 |
| 20160051955 | METHODS FOR SURFACTANT REMOVAL FROM NANOPARTICLE SUSPENSIONS - The present disclosure relates to the cleansing of nanoparticles in aqueous cationic surfactant solutions, including polyalkylammonium salts such as cetyltrimethylammonium bromide, as demonstrated by surfactant exchange, followed by the addition of peptizing agents to stabilize the cleansed nanoparticle solutes. | 02-25-2016 |
| 20160049542 | HOMOGENEOUS PRECURSOR FORMATION METHOD AND DEVICE THEREOF - A direct solution method based on a versatile amine-thiol solvent mixture which dissolves elemental metals, metal salts, organometallic complexes, metal chalcogenides, and metal oxides is described. The metal containing and metal chalcogenide precursors can be prepared by dissolving single or multiple metal sources, chalcogens, and/or metal chalcogenide compounds separately, simultaneously, or stepwise. Multinary metal chalcogenides containing at least one of copper, zinc, tin, indium, gallium, cadmium, germanium, and lead, with at least one of sulfur, selenium, or both are obtained from the above-mentioned metal chalcogenide precursors in the form of thin films, nanoparticles, inks, etc. Furthermore, infiltration of metal containing compounds into a porous structure can be achieved using the amine-thiol based precursors. In addition, due to the appreciable solubility of metal sources, metal chalcogenides, and metal oxides in the mixture of amine(s) and thiol(s), this solvent mixture can be used to remove these materials from a system. | 02-18-2016 |
| 20160049227 | METHOD OF PRODUCING CONDUCTIVE PATTERNS OF NANOPARTICLES AND DEVICES MADE THEREOF - A method of processing a liquid material. The method includes mixing a liquid material with a solvent, wherein the solvent has a constituent capable of coating the particles of the material. The liquid material mixed with the solvent is then particlized, deposited on a substrate and activated to form a pre-defined electrically conductive pattern. Particlization methods include sonication and the deposition methods include ink-jet printing. Activation methods include applying mechanical pressure. The method can be used to produce electronic devices. The electronic devices made by the method include strain gauges. The substrates utilized for making the electronic devices utilizing the method can be wearable or stretchable or both. | 02-18-2016 |
| 20160046924 | COMPOSITES MATERIAL WITH SUSPENDED PARTICLES AND METHOD OF USING THE SAME - An intermediate composite capable of transferring a biological or chemical material to be patterned on a surface. The intermediate composite includes a hydrogel, and particles suspended in the hydrogel, generating a particle-gel composite (composite), the composite is configured to absorb a biological or chemical material (agent), and further configured to deposit the agent when the composite is positioned proximate to a surface on which the agent is to be deposited. | 02-18-2016 |
| 20160023916 | SYNTHESIS OF METAL OXIDE-BASED THERMOELECTRIC MATERIALS FOR HIGH TEMPERATURE APPLICATIONS - Nanowire synthesis and one dimensional nanowire synthesis of titanates and cobaltates. Exemplary titanates and cobaltates that are fabricated and discussed include, without limitation, strontium titanate (SrTiO | 01-28-2016 |
| 20160022517 | MOBILITY-ASSISTANCE APPARATUS AND METHOD OF USING SAME - A mobility-assistance apparatus is disclosed. The apparatus comprises a wheelchair with a seat and frame and a walker coupled to the wheelchair. The walker is configured to be integrated into the wheelchair, such that the walker width is about the same as the wheelchair width. A wheelchair assistant is also disclosed which includes a walker and a seat lift mechanism, the wheelchair assistant being capable of integrated into a wheel chair such that the walker width is about the same as the wheelchair width. A mobility assistant apparatus is disclosed wherein the wheelchair assistant including a walker and seat lift mechanism is integrated into a wheelchair. | 01-28-2016 |
| 20160018811 | METHOD FOR CONTROLLING FLOW LOCALIZATION IN MACHINING PROCESSES - A method for controlling flow localization in machining process is disclosed. By application of a constraint of sufficient level in the deformation zone and modifying the surface boundary conditions, suppression of unsteady flow and flow instabilities is achieved. The method enhances machined component quality by ensuring a uniform deformation state on the machined surface. Machined components are produced by ensuing uniform deformation by adopting constrained-cutting process for suppressing the instabilities and unsteady flow through a pre-determined location of the constraint of the constrained machining process relative to the machining tool. | 01-21-2016 |
| 20160018334 | In-situ Combined Sensing of Uniaxial Nanomechanical and Micromechanical Stress with Simultaneous Measurement of Surface Temperature Profiles by Raman Shift in Nanoscale and Microscale Structures - Embodiments of the present disclosure include separating a measured Raman shift signal into mechanical and thermal components when a uniaxial compressive load is applied in situ. In some embodiments, in situ uniaxial compressive loads are applied on examined specimens from room temperature to 150° C. In alternate embodiments, Raman shift measurements are performed as a function of strain at constant temperature and/or as a function of temperature at constant strain levels. It was realized that the Raman shift measured at a given temperature under a given level of applied stress can be expressed as a summation of stress-induced Raman shift signal and temperature-induced Raman shift signal measured separately. Such a separation of Raman shift signal is utilized by various embodiments to measure localized change in thermal conductivity and/or mechanical stress of structures (e.g., semiconductor structures) under applied stress. | 01-21-2016 |
| 20160004060 | HIGH FRAME-RATE MULTICHANNEL BEAM-SCANNING MICROSCOPY - A beam-scanning optical design is described for achieving up to kHz frame-rate optical imaging on multiple simultaneous data acquisition channels. In one embodiment, two fast-scan resonant mirrors direct the optical beam on a circuitous trajectory through the field of view, with the trajectory repeat-time given by the least common multiplier of the mirror periods. Dicing the raw time-domain data into sub-trajectories combined with model-based image reconstruction (MBIR) 3D in-painting algorithms allows for effective frame-rates much higher than the repeat time of the Lissajous trajectory. Because sub-trajectory and full-trajectory imaging are different methods of analyzing the same data, both high-frame rate images with relatively low resolution and low frame rate images with high resolution are simultaneously acquired. | 01-07-2016 |
| 20150380988 | MAGNETIC RESONANCE COUPLING ARRANGEMENT - A wireless power transfer system is disclosed. The system includes a first resonator having a first resonant frequency ω | 12-31-2015 |
| 20150374451 | MESOSCOPIC TUMOR MICROENVIRONMENT IMAGING WITH IMPROVED CONTRAST - A mesoscopic imaging and surgical guidance apparatus. The apparatus includes an image capturing path, including a telecentric lens which receives backscattered light from a light which illuminates tissue in vivo with diffused light or collimated light and transforms the received light into an orthographic view, an image capturing device which captures the orthographic view, a processing unit configured to process the captured orthographic view to thereby generate a guidance image, and a projection path, including a light source configured to project the generated guidance image through the telecentric lens on to the tissue to guide surgical operations. | 12-31-2015 |
| 20150371695 | ELECTRONIC MEMORY INCLUDING ROM AND RAM - An electronic data-storage apparatus having ROM embedded in an STT-MRAM. The apparatus comprises at least two bit lines, a plurality of bit cells, each including, connected to a source line (SL), a series connection (in any order) of a selection element (e.g., transistor gated by word line WL), a resistive storage element (e.g., MTJ), and a permanent connection to one of the bit lines (e.g., BL | 12-24-2015 |
| 20150364898 | LASER WITH SUB-WAVELENGTH HOLE ARRAY IN METAL FILM - A sub-wavelength scale optical lasing device, for the controlled transfer of a signal in nano- and other small-scale technologies. An array of sub-wavelength size holes is first milled, or otherwise embedded, into a thin metal film. This film is combined with optically active media to compensate for losses of the metal. Optical signals are emitted in the active media, and then transferred to the metal so that surface plasmon polaritons are excited. Lasing occurs as a result of the compensation of plasmonic losses by the available optical gain. | 12-17-2015 |
| 20150351177 | SOLAR ENERGY HARVESTING WITH LIGHT EMITTING DIODES - An apparatus having a plurality of photonic devices electrically coupled to each other, each photonic device selectively configured to operate in a first mode as a light generating device when an electrical current is provided to the device by converting electrical energy to light. The device is further configured to operate in a second mode as a photovoltaic cell when no electrical current is provided to the device by converting light to electrical energy. A switching network coupled to the plurality of photonic devices. Each switch in the switching network may be configured to allow selection of the first or second mode for a respective photonic device of the plurality of photonic devices. The switching network may be coupled to a bi-direction DC-DC converter. | 12-03-2015 |
| 20150349026 | ELECTRONIC MEMORY USING MEMRISTORS AND CROSSBARS - A memory system comprising a plurality of layers of spaced-apart row electrodes, each having a dorsal and a ventral side, a plurality of layers of spaced-apart column electrodes, each having a dorsal and a ventral side is, and a plurality of layers of spaced-apart memristors arranged so that each of the row electrodes and each of the column electrodes is in contact with at least one memristor on the dorsal side thereof and with at least one memristor on the ventral side thereof. | 12-03-2015 |
| 20150323687 | LINEAR FITTING OF MULTI-THRESHOLD COUNTING DATA - The present disclosure provides a system and method for efficiently mining multi-threshold measurements acquired using photon counting pixel-array detectors for spectral imaging and diffraction analyses. Images of X-ray intensity as a function of X-ray energy were recorded on a 6 megapixel X-ray photon counting array detector through linear fitting of the measured counts recorded as a function of counting threshold. An analytical model is disclosed for describing the probability density of detected voltage, utilizing fractional photon counting to account for edge/corner effects from voltage plumes that spread across multiple pixels. Three-parameter fits to the model were independently performed for each pixel in the array for X-ray scattering images acquired for 13.5 keV and 15.0 keV X-ray energies. From the established pixel responses, multi-threshold composite images produced from the sum of 13.5 keV and 15.0 keV data can be analytically separated to recover the monochromatic images through simple linear fitting. | 11-12-2015 |
| 20150320799 | CHIMERIC ANTIGEN RECEPTOR-EXPRESSING T CELLS AS ANTI-CANCER THERAPEUTICS - Cytotoxic lymphocytes expressing chimeric antigen receptors (CAR) that target and bind small conjugate molecules (SCM) are disclosed, as well as methods of using the cells and the SCMs in the treatment of cancer. | 11-12-2015 |
| 20150309218 | ULTRA-THIN, PLANAR, PLASMONIC METADEVICES - An ultra-thin planar device is used for arbitrary waveform formation on a micrometer scale, regardless of the incident light's polarization. Patterned perforations are made in a 30 nm-thick metal film, creating discrete phase shifts and forming a desired wavefront of cross-polarized, scattered light. The signal-to-noise ratio of these devices is at least one order of magnitude higher than current metallic nano-antenna designs. The focal length of a lens built on such principle can also be adjusted by changing the wavelength of the incident light. All proposed embodiments can be embedded, for example, on a chip or at the end of an optical fiber. | 10-29-2015 |
| 20150309126 | WIRELESS POSITION SENSING USING MAGNETIC FIELD OF SINGLE TRANSMITTER - A positioning system for determining the location of a receiver relative to a transmitter. The system includes a transmitting coil having a known orientation with respect to the earth's coordinate system and configured to transmit a periodic signal during a positioning event, at least one receiver including a sensing unit for measuring the magnetic field vector produced by the transmitting coil and the orientation of the receiver with respect to the earth's coordinate system, and at least one computing unit configured to estimate a position and orientation of the receiver with respect to the transmitter's coordinate system using the measured magnetic field vector, the measured orientation with respect to the earth's coordinate system, and the known orientation of the transmitting coil with respect to the earth's coordinate system. | 10-29-2015 |
| 20150309001 | METHODS OF ANALYZING CRUDE OIL - The invention generally relates to methods of analyzing crude oil. In certain embodiments, methods of the invention involve obtaining a crude oil sample, and subjecting the crude oil sample to mass spectrometry analysis. In certain embodiments, the method is performed without any sample pre-purification steps. | 10-29-2015 |
| 20150308861 | WIRELESS POSITION SENSING USING MAGNETIC FIELD OF TWO TRANSMITTERS - A positioning system for determining the location of a receiver relative to a transmitter. The system includes two transmitting coils configured to transmit a periodic signal with a respective selected frequency during a positioning event, wherein the frequencies of the two signals transmitted by the two transmitting coils during the positioning event are different. A receiver includes a sensing unit for measuring the magnetic field vectors produced by the two simultaneously transmitting coils. A computing unit is configured to use the measured magnetic field vectors to calculate the position and orientation of the receiver with respect to the transmitter's coordinate frame. | 10-29-2015 |
| 20150299246 | N-SUBSTITUTED INDENOISOQUINOLINES AND SYNTHESES THEREOF - N-Substituted indenoisoquinoline compounds, and pharmaceutical formulations of N-substituted indenoisoquinoline compounds are described. Also described are processes for preparing N-substituted indenoisoquinoline compounds. Also described are methods for treating cancer in mammals using the described N-substituted indenoisoquinoline compounds or pharmaceutical formulations thereof. | 10-22-2015 |
| 20150292077 | Methods For Directed Irradiation Synthesis With Ion and Thermal Beams - A method for fabricating structures on substrate having a substrate surface includes providing a set of control parameters to an ion beam source and thermal source corresponding to a desired nanostructure topology. The method also includes forming a plurality of nanostructures in a first surface area of the substrate by exposing the substrate surface to an ion beam from the ion beam source and thermal energy from the thermal source. The ion beam has a first area of effect on the substrate surface, and the thermal energy has an second area of effect on the substrate surface Each of the first area and the second area includes the first surface area. In other words, the coincident beams under the set of control parameters produces a plurality of nano structures. | 10-15-2015 |
| 20150287544 | SUPER-CAPACITOR AND ARRANGEMENT FOR MINIATURE IMPLANTABLE MEDICAL DEVICES - An energy storage device includes first and second electrodes and a solid state electrolyte. The first electrode includes carbon nanotubes, a conductive polymer, and a metallization on said carbon nanotubes. The second electrode similarly includes carbon nanotubes, a conductive polymer, and a metallization on said carbon nanotubes. The solid state electrolyte is disposed at least in part between the first electrode and the second electrode. In at least some embodiments, the conductive polymer of the first electrode includes polyaniline, and the metallization of the first electrode is a gold metallization. | 10-08-2015 |
| 20150285953 | TITANIUM NITRIDE BASED METAMATERIAL - A titanium nitride-based metamaterial, and method for producing the same, is disclosed, consisting of ultrathin, smooth, and alternating layers of a plasmonic titanium nitride (TiN) material and a dielectric material, grown on a substrate to form a superlattice. The dielectric material is made of A | 10-08-2015 |
| 20150279648 | LASER DESORPTION IONIZATION MASS SPECTROMETRY USING A PARTICULATE SEPARATION BED - A self-assembled engineered lattice of nanometer-scale silica particles, or other suitable particles generally resembling regularly-sized spheres, is configured in a separation bed for electrophoresis, isoelectric focusing, chromatography, or other voltage-induced separation of analytes. After separation, the analytes are immobilized on the separation bed and then ionized using matrix-assisted laser desorption/ionization (MALDI) for use with a mass spectrometer. The nanoparticles can be coated with polymers that activate to immobilize the analytes or assist with MALDI. The separation can occur in two dimensions. | 10-01-2015 |
| 20150276674 | IMMUNOASSAYS USING COLLOIDAL CRYSTALS - The present invention provides systems, methods and kits which enable or utilize an immunologically-based assay, such as a Western immunoassay, to separate, detect or to monitor an analyte or a mixture of analytes such as biomolecules. | 10-01-2015 |
| 20150275254 | ENZYME LOADING, CELLULOSE HYDROLYSIS, AND INHIBITION OF CELLOBIOHYDROLASES USING LIQUID HOT WATER PRETREATMENT - Disclosed herein are methods for extracting sugars from cellulose-containing sources to achieve high glucose yields while greatly reducing the amount of cellulase enzyme needed. | 10-01-2015 |
| 20150273094 | GENERATION OF MICROBIOCIDE INSIDE A PACKAGE UTILIZING A CONTROLLED GAS COMPOSITION - An apparatus and method of producing an atmospheric non-equilibrium plasma (ANEP) in a sealed container having a selected working gas and an object to be treated is described. A variety of working gas mixtures including air, O | 10-01-2015 |
| 20150269959 | NEAR FIELD TRANSDUCER FOR HEAT ASSISTED MAGNETIC RECORDING - An antenna for heat assisted magnetic recording is disclosed. The antenna includes an optically opaque material and an optically transparent material positioned on the optically opaque material, the optically transparent material includes a half bowtie shape which includes a first half-wing substantially shaped in form of a right angle trapezoid, having a height substantially equal to the overall height of the half bowtie, a second half-wing substantially shaped in form of a mirror image of the first half-wing and formed proximate and coupled to the first half-wing by a substantially rectangular aperture having an aperture width and an aperture height. The aperture height is as small as 1 nm. | 09-24-2015 |
| 20150269478 | COMPACT IMPLEMENTATION OF NEURON AND SYNAPSE WITH SPIN SWITCHES - A neuron and synapse implementation is disclosed which incorporates a circuit element that includes first and second nanomagnets and first and second fixed magnets. The first nanomagnet is inductively coupled to a first current carrying element, and is configured to change polarity responsive to current in the first current carrying element. In one example, the first current carrying element includes a spin Hall effect substrate. The second nanomagnet is magnetically coupled to the first nanomagnet, and is inductively coupled to a second current carrying element. The first fixed magnet is disposed on the second nanomagnet and has a first fixed polarity, and second fixed magnet disposed on the second nanomagnet and has a second fixed polarity. | 09-24-2015 |
| 20150269434 | DISPLAYING PERSONALIZED IMAGERY FOR IMPROVING VISUAL ACUITY - A method to generate an output image that improves observation of a target image viewed on a medium by an optical system is disclosed. The method includes receiving at least one target image by a processing system, receiving at least one parameter by the processing system, defining an error signal associated with the difference between calculated optical system observation of intermediate images and the at least one target image, minimizing the error signal, and generating an output image associated with the intermediate image having the minimized error. | 09-24-2015 |
| 20150261702 | COMPUTING ARCHITECTURE WITH CONCURRENT PROGRAMMABLE DATA CO-PROCESSOR - A coprocessor (PL) is disclosed. The PL includes a memory router, at least one collection block that is configured to transfer data to/from the memory router, each collection block includes a collection router that is configured to i) transfer data to/from the memory router, ii) transfer data to/from at least one collection router of a neighboring collection block, and iii) transfer data to/from blocks within the collection block, and at least one programmable operator that is configured to i) transfer data to/from the collection router, and ii) perform a programmable operation on data received from the collection router. | 09-17-2015 |
| 20150260655 | METHODS FOR MEASURING CONCENTRATIONS OF CHLORINATED SOLVENTS THROUGH RAMAN SPECTROSCOPIC OBSERVATION OF THE VIBRATIONAL MODES OF WATER - Method for determining concentration of a chlorinated solvent in a non-turbid aqueous solution sample containing the chlorinated solvent is disclosed. The method includes developing a calibration profile relating intensities of Raman returns at a predetermined Raman shift associated with O—H stretching region of water for non-turbid aqueous chlorinated solvent calibration solutions of known concentrations. Intensity of Raman return at the predetermined Raman shift associated with O—H stretching region of the non-turbid aqueous solution sample is measured and compared to the calibration profile to determine the concentration of the chlorinated solvent in the non-turbid aqueous solution sample. For turbid solution samples, a method using turbidity-corrected intensity for the solution sample is disclosed. Alternatively, for turbid solution samples, a method employing a calibration profile utilizing turbid calibration solutions is disclosed. | 09-17-2015 |
| 20150247960 | HOLEY OPTICAL DEVICE - A planar optical device, comprised of sets of nanometer-scale holes milled into a thin metal or ceramic film of subwavelength thickness serves to form arbitrary waveform of light. The holes form a pattern, preferrably rings, of various sizes in order to achieve a given phase front of light due to photonic effect. When designed as a lens, the device focuses incident light into a tight focal spot. In symmetric design, the focusing property of the device does not depend on the incident polarization angle. The lens can be manufactured based on high-throughput fabrication methods and easily integrated with a chip or placed at the end of an optical fiber. | 09-03-2015 |
| 20150247815 | CORROSION SENSOR AND METHOD OF USING SAME - A corrosion sensor to automatically monitor the extent of corrosion in various structures is disclosed. The corrosion sensor includes a first part made substantially similar in material construction to a structure, corrosion on which is to be sensed by the corrosion sensor, and a second part made of a corrosion-resistant material, the first and second parts being separated by a medium, thereby forming a capacitor. The capacitor configured such that change in the capacitance provides a measure of corrosion occurring in the structure. | 09-03-2015 |
| 20150236841 | COMMUNICATING DATA USING BACKSCATTER MODULATION - A system and method for full duplex wireless communication is disclosed. The system utilizes backscatter modulation of a first signal received by a guest device from a basestation to transmit a guest device message to a host basestation. The guest device utilizes the same antenna to both receive and transmit message signals. | 08-20-2015 |
| 20150236247 | NON-VOLATILE SPIN SWITCH - A circuit element includes first and second nanomagnets and first and second fixed magnets. The first nanomagnet is inductively coupled to a first current carrying element, and is configured to change polarity responsive to current in the first current carrying element. In one example, the first current carrying element includes a spin Hall effect substrate. The second nanomagnet is magnetically coupled to the first nanomagnet, and is inductively coupled to a second current carrying element. The first fixed magnet is disposed on the second nanomagnet and has a first fixed polarity, and second fixed magnet disposed on the second nanomagnet and has a second fixed polarity. | 08-20-2015 |
| 20150218951 | INTERWOVEN CHANNELS FOR INTERNAL COOLING OF AIRFOIL - An apparatus and method for passing fluid flow through at least a portion of a blade of turbomachinery such as a gas turbine or the like. The fluid flow is directed through a plurality of flow channels which are interwoven with each other. Each flow channel is non-intersecting with any other flow channel and thus does not contact fluid flowing within any other flow channel. The method and apparatus of this invention can be used to reduce heat transfer and thus reduce thermal stresses, particularly in the blade. | 08-06-2015 |
| 20150203924 | DIAGNOSTIC TOOLS FOR HERBICIDE RESISTANCE IN PLANTS - Embodiments of the present disclosure relate generally to kits for identifying herbicide resistant plants and methods for determining whether a plant is herbicide resistant. The methods are based on the discovery that some genes are over-expressed or under-expressed in herbicide resistant plants when compared to herbicide-sensitive plants prior to application of the herbicide. The methods include determining the expression level of the one or more genes of interest in a biological sample, such as via qRT PCR, and determining whether the biological sample is from an herbicide-resistant plant based on the expression level. In an embodiment, the kit and methods are used to identify glyphosate-resistant | 07-23-2015 |
| 20150202399 | PLATFORM FOR OXYGEN GENERATION AND DELIVERY - A platform for oxygen generation and delivery is disclosed. The platform includes a hydrophobic substrate with at least one hydrophilic region permeable to gas flow formed thereon having an oxygen generating compound embedded in the at least one hydrophilic region. The platform further includes a microfluidic network with an inlet and an outlet bonded to the hydrophobic substrate with at least one fluid exchange region fluidly coupled to the inlet and the outlet and substantially matching the least one hydrophilic region. The microfluidic network is configured to receive an oxygen rich fluid at the inlet, communicate the oxygen rich fluid to the at least one fluid exchange region to mix with the oxygen generating compound, causing a chemical reaction resulting in formation of oxygen and a chemical byproduct, and communicate the chemical byproduct to the outlet, where the oxygen is permeated out of the at least one hydrophilic region. | 07-23-2015 |
| 20150198534 | METHODS FOR MEASURING CONCENTRATIONS OF ANALYTES IN TURBID SOLUTIONS BY APPLYING TURBIDITY CORRECTIONS TO RAMAN OBSERVATIONS - A method of measuring the concentration of an analyte in a turbid solution containing the analyte and a solvent is disclosed. The method includes determining a turbidity value for the turbid solution based on a Raman line intensity calibration data set for the solvent. The method further includes determining turbidity correction factor based on the turbidity value and a Raman line calibration data set for the analyte and applying the turbidity correction factor to the Raman line intensity of the analyte in the turbid solution and calculating a turbidity-corrected Raman line intensity for the analyte in the turbid solution. The turbidity-corrected Raman line intensity of the analyte in the turbid solution is then used to determine the concentration of the analyte in the turbid solution utilizing previously developed calibration data sets relating Raman line intensity to analyte concentration in solutions of negligible turbidity. | 07-16-2015 |
| 20150196231 | GAIT PATTERN ANALYSIS FOR PREDICTING FALLS - A method for acquiring gait parameters of an individual is disclosed. The method includes capturing calibration images from foot marker placed on feet or shoes of an individual while an individual is standing still, the calibration images are obtained from a camera worn by the individual, capturing subsequent time-varying images from the foot markers while the individual is walking, and comparing the calibration images to the subsequent time-varying images by a processing unit that is coupled to the camera to determine changes between the initial relative image size of the foot markers and the time-varying images of the foot markers as a function of time to analyze gait of the individual. | 07-16-2015 |
| 20150177226 | Disease-on-a-Chip - The invention generally relates to a cell culture system for coculturing non-neoplastic and neoplastic cells on a planar member which more faithfully mimics the in vivo geometry of a lumen or a cavity. | 06-25-2015 |
| 20150155534 | IMPACT RESISTANT BATTERY ENCLOSURE SYSTEMS - Battery enclosure arrangements for a vehicular battery system. The arrangements, capable of impact resistance include plurality of battery cells and a plurality of kinetic energy absorbing elements. The arrangements further include a frame configured to encase the plurality of the kinetic energy absorbing elements and the battery cells. In some arrangements the frame and/or the kinetic energy absorbing elements can be made of topologically interlocked materials. | 06-04-2015 |
| 20150148370 | ALCOHOL-, DIOL-, AND CARBOHYDRATE-SUBSTITUTED INDENOISOQUINOLINES AS TOPOISOMERASE I INHIBITORS - The invention described herein pertains to substituted indenoisoquinoline compounds as described herein, wherein R | 05-28-2015 |
| 20150143913 | MULTI-MODAL SENSING FOR VEHICLE - Apparatuses and methods for detecting hidden or modified objects in a vehicle are disclosed. Embodiments include detection of vehicle irregularities, such as irregularities in the acoustical response of a vehicle tire as the tire rolls over a surface, irregularities in the orientation of the vehicle body, the response of a vehicle component (such as an axle, wheel, tire, etc.) to the vehicle moving over a surface, and the response of a vehicle component to vehicle generated vibrations. In alternate embodiments subsystems detecting different irregularities communicate with one another. | 05-28-2015 |
| 20150137039 | Homogeneous Mixtures for Nanoparticle Synthesis - Presented herein is a method for obtaining a dissolved selenium liquid mixture from solid selenium. The method involves mixing an amine solvent and a thiol solvent with the solid selenium to produce a liquid intermediate solution and removing a sulfur containing compound from the liquid intermediate solution to produce a dissolved selenium liquid mixture. A method for obtaining dissolved sulfur liquid mixture by mixing an amine with a thiol to produce a liquid solution that dissolves sulfur to produce a dissolved sulfur liquid mixture is also presented. In addition, a method for obtaining a dissolved sulfur and selenium liquid mixture from solid selenium and solid sulfur by mixing an amine solvent with a thiol solvent is presented. | 05-21-2015 |
| 20150133331 | METABOLITE BIOMARKERS FOR THE DETECTION OF LIVER CANCER - Methods for the detection and screening of hepatocellular carcinoma (HCC) patients and for the monitoring of HCC treatment using a panel or panels of small molecule metabolite biomarkers are disclosed. In other aspects, methods for detection and screening for the progression of high-risk conditions, such as HCV infections, to HCC and to monitoring treatment using a panel or panels of small molecule metabolite biomarkers are disclosed. The biomarkers are sensitive and specific for the detection of HCC, and can also be used to classify HCV infections that are regarded as precursors of HCC. | 05-14-2015 |
| 20150124514 | Lifetime of Ferroelectric Devices - A method and apparatus for increasing the lifetime of ferroelectric devices is presented. The method includes applying a waveform to the input pulse to increase the rise or fall time of the pulse. The waveform may comprise a ramp, a step, or combinations of both. The waveform may be symmetrical with respect to the rising and falling edges of the pulses. A temperature control device may also be operatively connected to increase the temperature of the device to increase lifetime. In other embodiments, a resistance may be operatively connected in series with the ferroelectric device to increase lifetime. | 05-07-2015 |
| 20150119612 | Multicomponent Dividing Wall Columns - For an n-component mixture (n≧3), an array of new distillation columns is disclosed with vertical partitions that allow independent control of the vapor flowrates in each partitioned zone, while operating the columns to produce constituent product streams. Specifically, all such more operable columns with vertical partitions for ternary and quaternary feed mixtures are illustrated. For a ternary feed, through extensive computation, the minimum heat duty for each of the new columns is same as for the FTC configuration. The new columns with vertical partitions become even more attractive when the vapor split between column sections must be controlled within a narrow range. Finally, it is disclosed how a new column with vertical partition(s) drawn for an n-component mixture can be adapted to distil feed mixtures that contain more than n-components. | 04-30-2015 |
| 20150083597 | Perforated MOS Structure for Single Biomolecule Detection - A perforated metal oxide semiconductor (MOS) structure for single biomolecule, virus, or single cell detection is disclosed. The structure includes a nanochannel formed through a sensing region configured to allow a solution containing particles to pass through the perforated MOS sensor. First and second terminals are configured to measure electrical parameters representative of change of electrical characteristics of the solution as the particle passes through the perforated MOS structure. | 03-26-2015 |
| 20150081238 | RF Signal Meter - A radio frequency (RF) meter configured to measure both scalar power and phase information is disclosed. The meter performs a calibration to account for properties of an external coupler connected to the meter inputs. Internal couplers are optionally provided which direct the input signals to a phase detector. The meter is optionally connected to a display and network connections for transmitting the scalar power and phase information. | 03-19-2015 |
| 20150079621 | Motility-Contrast Imaging for Oocyte and Embryo Viability Assessment - A method and system is provided for evaluating viability of oocytes and embryos comprising imaging an oocyte or embryo using motility contrast imaging; generating temporal contrast and spatial contrast data for the cells; generating a cell viability value as a function of the temporal and spatial contrast data; and comparing the cell viability value to a predetermined value indicative of a cell suitable for use in an in vitro fertilization program. | 03-19-2015 |
| 20150072624 | PHASE COMPENSATION FILTERING FOR MULTIPATH WIRELESS SYSTEMS - A wireless communication system is disclosed. The system includes a transmitter which includes a data source configured to provide data to be transmitted, a modulator configured to modulate the data, a pre-filter configured to apply a filter to the modulated data generating pre-filtered data, and a transmitter antenna configured to receive the pre-filtered data and to transmit the pre-filtered data, the pre-filter based on a phase compensation topology that is based on channel characteristics between the transmitter and a receiver, the frequency response of the pre-filter based on spectral phase information of the channel such that the frequency response at the receiver is proportional to the magnitude of the channel frequency response. | 03-12-2015 |
| 20150068392 | FLEXIBLE PRINTED CIRCUIT BOARD PICKUP FOR STRINGED INSTRUMENTS AND METHOD OF USING THE SAME - A retrofit pickup assembly for stringed instruments is disclosed. The retrofit pickup assembly includes an existing coil and existing or new magnets and a flexible circuit having a plurality of wires and two connectors. A pickup assembly for new stringed instruments is also disclosed utilizing the same principles. A method of retrofitting an existing pickup assembly for stringed instruments is also disclosed. | 03-12-2015 |
| 20150068309 | SYSTEM FOR WEIGHING INDIVIDUAL MICRO- AND NANO- SIZED PARTICLES - A device for weighing micro- and nano-sized particles. The device includes a base portion, an oscillator coupled to the base portion and configured to vibrate the base portion, a first cantilevered beam coupled to the base portion, a second cantilevered beam coupled to the base portion, a first plurality of fingers coupled to the first cantilevered beam near the tip inwardly pointing toward the second cantilevered beam, and a second plurality of fingers coupled to the second cantilevered beam near the tip inwardly pointing toward the first cantilevered beam. | 03-12-2015 |
| 20150056605 | IDENTIFICATION OF BLOOD BASED METABOLITE BIOMARKERS OF PANCREATIC CANCER - The present disclosure relates to a panel of a plurality of metabolite species that is useful for the identification or detection of subjects having pancreatic cancer, including methods for identifying such metabolic biomarkers within biological samples. The disclosure also includes a statistical model for predicting the presence of pancreatic cancer in a subject's biofluid by quantifying and comparing positive and negative fold changes in metabolite species' concentration; comparing the subject's metabolite species' concentrations to a predetermined value. | 02-26-2015 |
| 20150049982 | Passive Optical Diode on Semiconductor Substrate - An optical device includes a first optical cavity, a second optical cavity, a first light guide and a second light guide. Each of the first and second optical cavities is formed on a semiconductor substrate, and is configured to store light. The first light guide has an input, and is optically coupled to the first optical cavity by a first coupling strength. In addition, the first light guide is optically coupled to the second optical cavity by a second coupling strength. The second light guide has an output, and is coupled to the second optical cavity by a third coupling strength. The first coupling strength is greater than the second coupling strength, and the third coupling strength is greater than the second coupling strength. | 02-19-2015 |
| 20150040978 | SOLAR-CELL EFFICIENCY ENHANCEMENT USING METASURFACES - A solar-energy module is disclosed. The module includes a first electrode configured to receive incident visible light with a different refractive index than the medium through which light travels prior to becoming incident on the first electrode, the first electrode having a first metasurface arrangement formed through the first electrode, and configured to selectively i) match the optical impedances of the first electrode and the medium, and ii) cause light to be refracted substantially away from normal refraction angle, a photon-absorbing material coupled to the first electrode on a first surface of the photon-absorbing material and configured to receive refracted light through the first electrode and adapted to produce an electrical current in response to the refracted light, length of the photon absorbing material substantially larger than thickness of the photon-absorbing material, and a second electrode coupled to the photon-absorbing material on a second surface of the photon-absorbing material. | 02-12-2015 |
| 20150023987 | IMMUNOGENIC COMPOSITIONS AND REAGENTS FOR PREPARING - The invention described herein pertains to compounds and conjugates, to compositions, complexes and formulations comprising the compounds and/or conjugates, and to methods of use of the compounds, conjugates and their compositions, complexes and formulations in vaccines and vaccinations and generating immune responses. | 01-22-2015 |
| 20150010835 | HIGH AND RAPID HYDROGEN RELEASE FROM THERMOLYSIS OF AMMONIA BORANE NEAR PEM FUEL CELL OPERATING TEMPERATURES AND AMMONIA REMOVAL FOR HYDROGEN PEM FUEL CELLS - A system for generating and purifying hydrogen. To generate hydrogen, the system includes inlets configured to receive a hydrogen carrier and an inert insulator, a mixing chamber configured to combine the hydrogen carrier and the inert insulator, a heat exchanger configured to apply heat to the mixture of hydrogen carrier and the inert insulator, wherein the applied heat results in the generation of hydrogen from the hydrogen carrier, and an outlet configured to release the generated hydrogen. To purify hydrogen, the system includes a primary inlet to receive a starting material and an ammonia filtration subassembly, which may include an absorption column configured to absorb the ammonia into water for providing purified hydrogen at a first purity level. The ammonia filtration subassembly may also include an adsorbent member configured to adsorb ammonia from the starting material into an adsorbent for providing purified hydrogen at a second purity level. | 01-08-2015 |
| 20150010672 | Slowly Fermentable Soluble Dietary Fiber - The embodiments described herein provide a method for improving bowel health by increasing short chain fatty acid concentration in the colon of a mammal including administering to the mammal a composition having from about 0.1 grams to about 50 grams of a treated bran product. After administration, the treated bran product results in an increased short chain fatty acid production during fermentation in the colon as compared to untreated bran fermented in the colon. | 01-08-2015 |
| 20140376926 | SYSTEM AND METHOD FOR REMOVING FAR FIELD LIMITATIONS IN MICROWAVE PHOTONIC ARBITRARY WAVEFORM GENERATORS - A photonic waveform generator and a method of generating an electrical waveform based on a photonic signal are disclosed. The generator includes an input port for receiving an optical signal, a pulse shaper coupled to the input port and configured to Fourier transform the optical signal and apply a pre-distort waveform onto optical spectrum of the optical signal, a dispersive pulse stretcher coupled to the pulse shaper, an optical-to-electrical converter coupled to the dispersive pulse stretcher, and an output port coupled to the optical-to-electrical converter, the pre-distortion removes distortion of the electrical signal that exists in the absence of the pre-distortion caused by violation of far field limitation between the optical signal and the electrical signal. | 12-25-2014 |
| 20140371624 | WIRELESS INTERSTITIAL FLUID PRESSURE SENSOR - An implantable pressure sensor arrangement is disclosed. The arrangement includes a substrate, a coil positioned on the substrate, a flexible membrane positioned proximate to the coil and configured to be moveable with respect to the coil, thereby forming a fluid chamber, fluidly sealed from outside of the implantable pressure sensor arrangement, a porous membrane positioned on the flexible membrane and configured to transfer pressure from outside of the implantable pressure sensor arrangement onto the flexible membrane wherein a differential pressure is generated on the two sides of the flexible membrane thereby causing the flexible membrane to deflect towards and away from the coil, and an electrode coupled to the flexible membrane. | 12-18-2014 |
| 20140369596 | CORRELATING VIDEOS AND SENTENCES - A method of testing a video against an aggregate query includes automatically receiving an aggregate query defining participant(s) and condition(s) on the participant(s). Candidate object(s) are detected in the frames of the video. A first lattice is constructed for each participant, the first-lattice nodes corresponding to the candidate object(s). A second lattice is constructed for each condition. An aggregate lattice is constructed using the respective first lattice(s) and the respective second lattice(s). Each aggregate-lattice node includes a scoring factor combining a first-lattice node factor and a second-lattice node factor. respective aggregate score(s) are determined of one or more path(s) through the aggregate lattice, each path including a respective plurality of the nodes in the aggregate lattice, to determine whether the video corresponds to the aggregate query. A method of providing a description of a video is also described and includes generating a candidate description with participant(s) and condition(s) selected from a linguistic model; constructing component lattices for the participant(s) or condition(s), producing an aggregate lattice having nodes combining component-lattice factors, and determining a score for the video with respect to the candidate description by determining an aggregate score for a path through the aggregate lattice. If the aggregate score does not satisfy a termination condition, participant(s) or condition(s) from the linguistic model are added to the condition, and the process is repeated. A method of testing a video against an aggregate query by mathematically optimizing a unified cost function is also described. | 12-18-2014 |
| 20140361188 | Detection of Neutrinos - A flux detection apparatus can include a radioactive sample having a decay rate capable of changing in response to interaction with a first particle or a field, and a detector associated with the radioactive sample. The detector is responsive to a second particle or radiation formed by decay of the radioactive sample. The rate of decay of the radioactive sample can be correlated to flux of the first particle or the field. Detection of the first particle or the field can provide an early warning for an impending solar event. | 12-11-2014 |
| 20140360550 | NANOCRYSTAL COATED FLEXIBLE SUBSTRATES WITH IMPROVED THERMOELECTRIC EFFICIENCY - This disclosure examines using lead telluride nanocrystals as well as other materials suitable for thermoelectric conversion, particularly materials with high Figure of Merit values, as coatings on flexible substrates. | 12-11-2014 |
| 20140355644 | Wireless Sensor for Rotating Elements - A system for measuring a physical characteristic of a bearing includes a permanent magnet and a magnetic sensor. The permanent magnetic is coupled to at least a portion of a bearing, and has a magnetic field that changes as a function of the physical characteristic. For example, the permanent magnet has a magnetic characteristic that changes as a function of temperature. The magnetic sensor is operably disposed in a magnetic field sensing relationship with the permanent magnet, and is configured to generate a voltage signal and/or current signal corresponding to a sensed magnetic field. | 12-04-2014 |
| 20140353920 | Wireless Sensor for Rotating Elements - A system for measuring a physical characteristic of mechanical face seal includes a permanent magnet and a magnetic sensor. The permanent magnet is affixed to a structure proximate to a bearing surface of the mechanical face seal. The permanent magnet has a magnetic field that decreases as a function of temperature. The magnetic sensor is mounted on the mechanical face seal in a magnetic field sensing relationship with the permanent magnet. The magnetic sensor is configured to generate a voltage signal corresponding to a sensed magnetic field. | 12-04-2014 |
| 20140342993 | KINASE INHIBITORS AND USES THEREOF - The present invention relates to kinase inhibiting compositions and uses thereof. The invention further provides isolated kinase inhibiting peptides and uses thereof for inhibiting hyperplasia, for inhibiting the growth of neoplasms, and for inducing programmed cell death in a cell population. | 11-20-2014 |
| 20140342321 | GENERATIVE LANGUAGE TRAINING USING ELECTRONIC DISPLAY - Methods of conducting generative language training using a training corpus having a plurality of words and a plurality of stimuli are described. A stimulus is presented via an electronic display. A selection is received from visual representations of a plurality of the words represented on the display. It is determined whether the selected words correspond to the represented words in the stimulus. A mastery level can be determined based on correspondence of the responses and stimuli and the training corpus or sequence modified based on the mastery level. Another method includes receiving mastery-level data for multiple learners and determining a training sequence using relative difficulties determined from the mastery-level data. Another method includes determining a proficiency level using the correspondence of responses and, if the determined proficiency level corresponds to an intervention criterion, performing an intervention sequence including detecting word selections and unlocking inputs. | 11-20-2014 |
| 20140339014 | SOUND BARRIER SYSTEMS - A cellular material barrier system for reducing sound transmission. The cellular material system includes a planar cellular metamaterial arrangement which includes at least one unit cell, the unit cell includes a sound normalizing arrangement, and a planar metamaterial arrangement coupled to the sound normalizing arrangement on a first side, the planar metamaterial arrangement includes a plate, and a frame affixed to the plate, the sound normalizing arrangement configured to normalize incident sound received at non-normal angle to thereby convey sound at normal angles to the planar metamaterial arrangement, the unit cell further comprising a back layer that is coupled to the sound normalizing arrangement on a second side, opposite the first side, the back layer is made from a porous material, including at least one of a fibrous layer, polymeric foams, ceramic foams, and metallic foams. | 11-20-2014 |
| 20140336188 | N-SUBSTITUTED INDENOISOQUINOLINES AND SYNTHESES THEREOF - N-Substituted indenoisoquinoline compounds, and pharmaceutical formulations of N-substituted indenoisoquinoline compounds are described. Also described are processes for preparing N-substituted indenoisoquinoline compounds. Also described are methods for treating cancer in mammals using the described N-substituted indenoisoquinoline compounds or pharmaceutical formulations thereof. | 11-13-2014 |
| 20140322608 | MODIFIED GRAPHITIC ELECTRODES FOR ELECTROCHEMICAL ENERGY STORAGE ENHANCEMENT - A method of graphitic petal synthesis includes a step of providing a flexible carbon substrate, such as that including carbon microfibers. The method further includes the step of subjecting flexible carbon substrate to microwave plasma enhanced chemical vapor deposition. The resulting synthesized graphitic petal structure may optionally be coated with PANI. | 10-30-2014 |
| 20140315946 | NONPEPTIDE HIV-1 PROTEASE INHIBITORS - Novel compounds and compositions for treating patients in need of relief from HIV, AIDS and AIDS-related diseases are described. Methods for treating HIV, AIDS, and AIDS-related diseases using the compounds described herein are also described. | 10-23-2014 |
| 20140311708 | REFRIGERATION FROM GRAPHENE-BASED NANOEMITTERS - This disclosure presents the use of electrons as the ‘working fluid’ in conjunction with a solid nanomaterial that hinders electron coupling to the atomic lattice of the nanomaterial, i.e., they are out of equilibrium. The electrons can achieve very high effective temperatures with minimal heating of the solid lattice. These ‘hot’ electrons emit from the absorbing material, carrying both the light energy and energy acquired from the atomic lattice. Thus, the operation of this disclosure includes shining light on an object to make the object cool instead of heat. It is envisioned that one of ordinary skill in the art would find the operation quite counter-intuitive. | 10-23-2014 |
| 20140305804 | SENSORS AND METHODS OF MANUFACTURE THEREOF - The invention generally relates to sensors, methods of manufacture thereof, methods of use thereof for sensing analytes, such as small molecules and biomolecules, and methods of immobilization. In certain embodiments, the invention provides a multi-analyte sensor. The multi-analyte sensor includes a plurality of sensing electrodes. Each sensing electrode is functionalized with a different molecule (e.g., biomolecule), at least two of the sensing electrodes are spaced apart prior to and after functionalization by 100 μm or less, and there is no cross-talk between the plurality of sensing electrodes. | 10-16-2014 |
| 20140301983 | HYALURONIC ACID-BINDING SYNTHETIC PEPTIDOGLYCANS, PREPARATION, AND METHODS OF USE - This invention pertains to the field of hyaluronic acid-binding synthetic peptidoglycans and methods of forming and using the same. | 10-09-2014 |
| 20140299764 | LOW TEMPERATURE PLASMA PROBE AND METHODS OF USE THEREOF - The present invention generally relates to a low temperature plasma probe for desorbing and ionizing at least one analyte in a sample material and methods of use thereof. In one embodiment, the invention generally relates to a low temperature plasma probe including: a housing having a discharge gas inlet port, a probe tip, two electrodes, and a dielectric barrier, in which the two electrodes are separated by the dielectric barrier, in which application of voltage from a power supply generates a low temperature plasma, and in which the low temperature plasma is propelled out of the discharge region by the electric field and/or the discharge gas flow. | 10-09-2014 |
| 20140294036 | THERMOGRAPHY FOR BATTERY COMPONENT QUALITY ASSURANCE - Methods and apparatus for the detection of irregularities in a thin film by measurement of transient thermal response. | 10-02-2014 |
| 20140292381 | GRAPHENE-BASED FREQUENCY TRIPLER - A frequency tripler device is disclosed. The frequency tripler device includes a first graphene based field effect transistor (FET) of a first dopant type, having a gate, a drain, and a source, and a second graphene based FET of a second dopant type, having a gate, a drain, and a source, the gate of the first FET coupled to the gate of the second FET and coupled to an input signal having an alternating current (AC) signal of a first frequency, the combination of the first and second FETs generates an output signal with a dominant AC signal of a frequency of about three times the first frequency. | 10-02-2014 |
| 20140271484 | Methods of Imaging Inflammatory Diseases by Ligands Conjugated to Fluorescent Compounds - The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid or derivative thereof. The disclosure further describes methods of imaging of inflammatory diseases using the compounds. | 09-18-2014 |
| 20140271482 | SYNTHESIS AND COMPOSITION OF AMINO ACID LINKING GROUPS CONJUGATED TO COMPOUNDS USED FOR THE TARGETED IMAGING OF TUMORS - The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid or derivative thereof. The disclosure further describes methods and compositions for making and using the compounds, methods incorporating the compounds, and kits incorporating the compounds. | 09-18-2014 |
| 20140271476 | SYNTHESIS AND COMPOSITION OF AMINO ACID LINKING GROUPS CONJUGATED TO COMPOUNDS USED FOR THE TARGETED IMAGING OF TUMORS - The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid or derivative thereof. The disclosure further describes methods and compositions for making and using the compounds, methods incorporating the compounds, and kits incorporating the compounds. | 09-18-2014 |
| 20140271468 | ASTHMA IMAGING - The invention relates to methods of imaging asthma using ligand conjugates. More particularly, the invention relates to the use of ligands that bind to cells associated with asthma conjugated to a chromophore, or to a chemical moiety capable of emitting radiation, for administration to a diseased host for imaging asthma. | 09-18-2014 |
| 20140268560 | MOTORIZED MOUNT FOR SEATING SYSTEM - The present disclosure illustrates a motorized mount with a plurality of degrees of freedom coupled to a seating system. | 09-18-2014 |
| 20140264004 | SYSTEMS AND METHODS FOR ANALYZING A SAMPLE USING A MASS SPECTROMETRY PROBE CONFIGURED TO CONTACT THE SAMPLE - The invention generally relates to systems and methods for analyzing a sample using a mass spectrometry probe having a tip that is configured to contact a sample and retain a portion of the sample once the probe has been removed from the sample. | 09-18-2014 |
| 20140261609 | ULTRATHIN NANOWIRE-BASED AND NANOSCALE HETEROSTRUCTURE BASED THERMOELECTRONIC CONVERSION STRUCTURES AND METHOD OF MAKING THE SAME - A nano scale hetero structure tellurium-based nanowire structure is disclosed including a dumbbell-like crystalline heterostructure having a center rod-like portion and one octahedral structure connected to each end of each of the center rod-like portions, wherein the center rod-like portion is a bismuth-telluride nanowire structure and the octahedral structures are lead telluride. | 09-18-2014 |
| 20140256735 | METHOD FOR ASSESSING A LIVER OF A PATIENT HAVING A CHRONIC HEPATITIS B VIRUS INFECTION - The invention generally relates to method for assessing a liver of a patient having a chronic hepatitis B virus infection. In certain aspects, methods of the invention involve obtaining a sample from a patient having a chronic hepatitis B virus infection. An assay is conducted on the sample to determine a level of at least one biomarker regulated by Suz12/Znf198. The liver of the patient is then assessed based on the level of the at least one biomarker. Other aspects of the invention generally relate to reducing or eliminating replication of a hepatitis B virus, and preventing a chronic hepatitis B infection in a patient from progressing to a liver cancer. | 09-11-2014 |
| 20140255738 | BATTERY AND BATTERY-SENSING APPARATUSES AND METHODS - Apparatuses and methods for determining one or more performance related characteristics (such as state of charge and/or health) of one or more electrochemical cells that store and release electrical energy are disclosed. Embodiments include pressure and/or temperature sensors that sense a change in pressure resulting from the tendency of the electrochemical cell to change volume and/or the temperature of the one or more electrochemical cells as the electrochemical cell(s) are charged or discharged. Alternate embodiments include one or more calculating members that receive pressure and/or temperature information from the pressure and/or temperature sensing members and calculate a performance related characteristic of the electrochemical cell. Still further embodiments include determining one or more performance related characteristics of an electrochemical cell by sensing the tendency of an electrochemical cell to change volume (such as by sensing pressure) and/or by sensing the temperature as the electrochemical cell is charged or discharged. | 09-11-2014 |
| 20140242140 | FABRICATION METHOD FOR STRATIFIED AND LAYERED TISSUE TO REPAIR OSTEOCHONDRAL DEFECTS - Fabrication method for stratified and layered tissue to repair osteochondral defects. In a method of the present disclosure, the method comprises the step of applying a first direction magnetic field to a first quantity of a first collagen solution to align collagen within the first collagen solution in a first direction relative to the first direction magnetic field, forming a first layer of collagen. In a method of generating an aligned collagen layer of the present disclosure, the method comprises applying a first magnetic field at or greater than 0.1 Tesla to a layer of a first collagen solution defining a horizontal plane, within a temperature at or between 2° C. and 45° C., to generate an aligned collagen layer. | 08-28-2014 |
| 20140238306 | NESTING MATERIAL BALING AND DISPENSING SYSTEM FOR MOUSE ENVIRONMENTAL ENRICHMENT - A standardized nesting material for use in laboratory environments for rodents includes a latrining substrate, and at least one bale unit formed to include a fibrous scaffolding material, and an insulating material. The bale units are of standardized size and can be packaged and sterilized to provide improved wellbeing of the animals; reduced feed and labor costs; and improved scientific quality of the studies conducted on the animals. | 08-28-2014 |
| 20140237690 | AFM-COUPLED MICROSCALE RADIOFREQUENCY PROBE FOR MAGNETIC RESONANCE IMAGING AND SPECTROSCOPY - The present disclosure is discloses the development of a new device, system, and method that combines advantages of magnetic resonance and atomic force microscopy technologies, and the utility of the new device, system, and method for a wide range of biomedical and clinical researchers. According to one aspect of the present disclosure, a device for micro-scale spectroscopy is disclosed. The micro-scale spectroscopy device includes a beam having a distal end, a proximal end, a top surface and a bottom surface, where the beam is attached to an anchor at the proximal end and further includes a tip extending substantially perpendicular from the bottom surface at or near the distal end, and a coil having at least one turn mounted to the top surface of the beam at or near the distal end opposite the tip, where the coil is capable of both transmitting and sensing electromagnetic radiation. | 08-21-2014 |
| 20140234866 | EX VIVO FLOW CYTOMETRY METHOD AND DEVICE - The invention relates to a method for diagnosing a disease state mediated by pathogenic cells. The method comprises the steps of combining with an ex vivo patient sample a composition comprising a conjugate or complex of the general formula | 08-21-2014 |
| 20140231643 | DISCONTINUOUS ATMOSPHERIC PRESSURE INTERFACE - A method of interfacing atmospheric pressure ion sources, including electrospray and desorption electrospray ionization sources, to mass spectrometers, for example miniature mass spectrometers, in which the ionized sample is discontinuously introduced into the mass spectrometer. Discontinuous introduction improves the match between the pumping capacity of the instrument and the volume of atmospheric pressure gas that contains the ionized sample. The reduced duty cycle of sample introduction is offset by operation of the mass spectrometer under higher performance conditions and by ion accumulation at atmospheric pressure. | 08-21-2014 |
| 20140221420 | CCR5 ANTAGONISTS FOR TREATING HIV - Compounds that modulate the CCR5 chemokine receptor, pharmaceutical compositions containing them, and uses therefor in the treatment of HIV and related diseases are described. | 08-07-2014 |
| 20140219861 | METHOD OF PRODUCING PARTICULATE-REINFORCED COMPOSITES AND COMPOSITES PRODUCED THEREBY - A process for producing particle-reinforced composite materials through utilization of an in situ reaction to produce a uniform dispersion of a fine particulate reinforcement phase. The process includes forming a melt of a first material, and then introducing particles of a second material into the melt and subjecting the melt to high-intensity acoustic vibration. A chemical reaction initiates between the first and second materials to produce reaction products in the melt. The reaction products comprise a solid particulate phase, and the high-intensity acoustic vibration fragments and/or separates the reaction products into solid particles that are dispersed in the melt and are smaller than the particles of the second material. Also encompassed are particle-reinforced composite materials produced by such a process. | 08-07-2014 |
| 20140217535 | THIN FILM PHOTOVOLTAIC PANELS AND REPAIR METHODS - Conductive layer(s) in a thin film photovoltaic (TFPV) panel are divided by first scribe curves into photovoltaic cells connected in series. At least one of the layers is scribed to isolate a shunt defect in a cell from parts of that cell away from the defect. The isolation scribes can substantially follow or parallel current-flow lines established by the design of the panel. A TFPV panel can be altered by, using a controller, automatically locating a shunt defect and scribing at least one of the conductive layers along two spaced-apart second scribe curves. Each second scribe curve can intersect the two first scribe curves that bound the cell with the defect. The two second scribe curves can be on opposite sides of the defect. | 08-07-2014 |
| 20140213760 | Folate Receptor Binding Conjugates of Antifolates - Conjugates of antifolates, releasable linkers, and drugs, and pharmaceutical compositions containing them are described. The conjugates are useful for treating diseases arising from pathogenic cell populations. Methods for treating such diseases are also described. | 07-31-2014 |
| 20140203896 | Tunable Cavity Resonator Including A Plurality of MEMS Beams - A tunable cavity resonator includes a substrate, a cap structure, and a tuning assembly. The cap structure extends from the substrate, and at least one of the substrate and the cap structure defines a resonator cavity. The tuning assembly is positioned at least partially within the resonator cavity. The tuning assembly includes a plurality of fixed-fixed MEMS beams configured for controllable movement relative to the substrate between an activated position and a deactivated position in order to tune a resonant frequency of the tunable cavity resonator. | 07-24-2014 |
| 20140203796 | NANOELECTROMECHANICAL RESONATORS - A silicon device, e.g., a nanoelectromechanical resonator, has a silicon substrate; an oxide layer having a trench therein; a silicon device layer over the oxide layer; and a nanowire disposed at least partly over the trench. Substantially no oxide or polysilicon is over the nanowire in the trench. A polyimide layer over the silicon device layer includes an opening over the trench. A silicon device can include silicon-on-insulator layers and at least one complementary metal-oxide semiconductor transistor in addition to a nanowire substantially suspended over a trench. A system for measurement of a nanoresonator includes an AC source in series with the nanoresonator to provide an electrical signal thereto at a selected first frequency. Electrode(s) adjacent to and spaced apart from the nanoresonator are driven by voltage source. A detector detects a current through the nanoresonator. | 07-24-2014 |
| 20140202837 | LOW-COST PROCESS-INDEPENDENT RF MEMS SWITCH - A MEMS switch includes a semiconductor substrate, a movable cantilever and a cantilever anchor. The semiconductor substrate includes a device layer and a handle. The movable cantilever is formed in the semiconductor substrate, and is disposed over a void in the handle. The cantilever anchor is formed in the semiconductor substrate and defines a side wall of the void. A metal portion is formed on at least a portion of the movable cantilever. A metal contact is formed proximate an end of the movable cantilever. A biasing metal contact is formed adjacent the cantilever. The biasing metal contact is electrically disconnected from the metal contact. | 07-24-2014 |
| 20140198630 | FAILURE REPAIR SEQUENCE GENERATION FOR NODAL NETWORK - Failure repair sequence generation systems and methods may generate a repair sequence for nodes experiencing failure in a nodal-network-based system that meets acceptable performance metrics, such as acceptable total network damage, acceptable node-failure preventability rate, or a combination thereof. | 07-17-2014 |
| 20140196998 | DYNAMIC LOAD-ABSORBING MATERIAL AND ARTICLES - Dynamic load-absorbing materials suitable for use as cushion-type and armor-type materials, for example, of types that can be incorporated into protective gear, equipment, armor, vehicles, and various other structures, or used for the isolation and dissipation of vibratory loads, such as vibration isolators used to support avionic equipment. The impact-absorbing materials include a matrix material ( | 07-17-2014 |
| 20140196833 | METHOD AND SYSTEM OF VACUUM ASSISTED RESIN TRANSFER MOLDINGS FOR REPAIR OF COMPOSITE MATERIALS AND STRUCTURE - The present disclosure provides a method of repairing a damaged portion of a panel formed of composite material. The method includes preparing the damaged portion for repair and applying a pressure responsive adhesive layer to substantially cover the damaged portion. The method also includes disposing a vacuum-assisted resin transfer molding repair patch assembly to substantially cover the damaged portion and substantially covering the repair patch assembly with a vacuum bag assembly. Resin is introduced into and impregnates the repair patch assembly. The repair patch assembly is cured after being impregnated. | 07-17-2014 |
| 20140194383 | MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME - Described herein are monomers capable of forming a biologically useful multimer when in contact with one, two, three or more other monomers in an aqueous media. In one aspect, such monomers may be capable of binding to another monomer in an aqueous media (e.g. in vivo) to form a multimer, (e.g. a dimer). Contemplated monomers may include a ligand moiety, a linker element, and a connector element that joins the ligand moiety and the linker element. In an aqueous media, such contemplated monomers may join together via each linker element and may thus be capable of modulating one or more biomolecules substantially simultaneously, e.g., modulate two or more binding domains on a protein or on different proteins. | 07-10-2014 |
| 20140192485 | VEHICLES, POWER ELECTRONICS MODULES AND COOLING APPARATUSES WITH SINGLE-PHASE AND TWO-PHASE SURFACE ENHANCEMENT FEATURES - Jet-impingement, two-phase cooling apparatuses and power electronics modules having a target surface with single- and two-phase surface enhancement features are disclosed. In one embodiment, a cooling apparatus includes a jet plate surface and a target layer. The jet plate surface includes a jet orifice having a jet orifice geometry, wherein the jet orifice is configured to generate an impingement jet of a coolant fluid. The target layer has a target surface, single-phase surface enhancement features, and two-phase surface enhancement features. The target surface is configured to receive the impingement jet, and the single-phase surface enhancement features and the two-phase enhancement features are arranged on the target surface according to the jet orifice geometry. The single-phase surface enhancement features are positioned on the target surface at regions associated with high fluid velocity, and the two-phase surface enhancement features are positioned on the target surface at regions associated with low fluid velocity. | 07-10-2014 |
| 20140187547 | AZAINDENOISOQUINOLINE TOPOISOMERASE I INHIBITORS - The invention described herein pertains to substituted azaindenoisoquinoline compounds, in particular 7-, 8-, 9-, and 10-azaindenoisoquinoline compounds, which are inhibitors of topoisomerase I, processes and intermediates for their syntheses, pharmaceutical compositions of the compounds, and methods of using them in the treatment of cancer. | 07-03-2014 |
| 20140183351 | ION GENERATION USING MODIFIED WETTED POROUS MATERIALS - The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a wetted porous substrate that substantially prevents diffusion of sample into the substrate. In other aspects, the invention generally relate to ion generation using a wetted porous material and a drying agent. In other aspects, the invention generally relates to ion generation using a modified wetted porous substrate in which at least a portion of the porous substrate includes a material that modifies an interaction between a sample and the substrate. | 07-03-2014 |
| 20140179754 | FUSED TRICYCLIC ETHER CARBAMATES AND THEIR USE - Tricylic ether carbamates that inhibit HIV proteolytic enzymes and processes for preparing the compounds are describes. Methods of using the disclosed compounds for treating patients infected with HIV are also described. | 06-26-2014 |
| 20140179629 | SLOWLY DIGESTING STARCH AND FERMENTABLE FIBER - Compositions which provide slowly digestible starch and a source of fermentable dietary fiber. Microparticles in which starch is entrapped in a crosslinked matrix to provide dietary benefit. Such microparticles are used to deliver glucose to targeted regions in the small intestine for beneficial physiological effects, and fermentable dietary fiber to the colon to improve colon health and to treat diseases of the colon. Microparticles can be employed to selectively deliver fermentable dietary fiber to targeted portions of the colon. | 06-26-2014 |
| 20140165738 | Feedback System and Method for Assessing Fixation and Stability of Implantable Leads - A lead fixation and stability feedback assembly for testing stability and anchoring of a fixation tip of a distal end of an implantable lead to a tissue is disclosed. The assembly includes a first member including a first coupling arrangement configured to couple to a proximal end of an implantable lead, wherein the proximal end of the implantable lead is coupled to a distal end of the implantable lead configured to be anchored to a tissue, and a second member including a second coupling arrangement configured to couple the first member to the second member, the second coupling arrangement configured to decouple the second member from the first member when a predetermined force is applied to pull the second member away from the first member to thereby test the anchoring of the distal end of the implantable lead to the tissue. | 06-19-2014 |
| 20140162903 | Metabolite Biomarkers For Forecasting The Outcome of Preoperative Chemotherapy For Breast Cancer Treatment - The present disclosure relates to a panel of metabolite species that is useful for forecasting the outcome of preoperative chemotherapy for the treatment of breast cancer, including methods for identifying and using such metabolite species that can be measured in biological samples taken before treatment. In preferred embodiments, a method of forecasting a treatment outcome before subjecting a breast cancer patient to preoperative chemotherapy is disclosed that includes measuring the concentration of at least one metabolite species in a sample of a biofluid taken from the breast cancer patient before preoperative chemotherapy treatment. | 06-12-2014 |
| 20140161340 | ITERATIVE RECONSTRUCTION - An improved iterative reconstruction method to reconstruct a first image includes generating an imaging beam, receiving said imaging beam on a detector array, generating projection data based on said imaging beams received by said detector array, providing said projection data to an image reconstructor, enlarging one of a plurality of voxels and a plurality of detectors of the provided projection data, reconstructing portions of the first image with the plurality of enlarged voxels or detectors, and iteratively reconstructing the portions of the first image to create a reconstructed image. | 06-12-2014 |
| 20140160266 | SINGLE IMAGE SUPER-RESOLUTION MICROSCOPY AND TELESCOPE SYSTEMS - Image resolution enhancement techniques are implemented using a single image an unstructured broadband illumination. By placing an axicon and a convex lens pair in an optical path of a microscope, telescope, or the object system, between the system and an image capture pickup device (e.g., a camera) the maximum resolution of the system may be increased through the formation of an interference pattern at the image capture device. | 06-12-2014 |
| 20140158882 | SYSTEMS AND METHODS FOR TRANSFER OF IONS FOR ANALYSIS - The invention generally relates to systems and methods for transferring ions for analysis. In certain embodiments, the invention provides a system for analyzing a sample including an ionizing source for converting molecules of a sample into gas phase ions in a region at about atmospheric pressure, an ion analysis device, and an ion transfer member operably coupled to a gas flow generating device, in which the gas flow generating device produces a laminar gas flow that transfers the gas phase ions through the ion transfer member to an inlet of the ion analysis device. | 06-12-2014 |
| 20140157777 | PRODUCTION OF HYDROGEN USING AN ANAEROBIC BIOLOGICAL PROCESS - Various embodiments of the present invention pertain to methods for biological production of hydrogen. More specifically, embodiments of the present invention pertain to a modular energy system and related methods for producing hydrogen using organic waste as a feed stock. | 06-12-2014 |
| 20140151542 | DETECTION OF BURIED EXPLOSIVES - A system and method are described for capturing and analyzing gamma rays from neutron excitation of a region in 3-space being analyzed for explosives. A processor analyzes the results, determining whether underground explosives are present in a particular region of the ground. In one embodiment, one gamma ray energy band is used to infer an amount of silicon in the region, while another indicates the combined amount of silicon and nitrogen. The concentration of nitrogen in the region is inferred and used to trigger an “explosive found” or a “no explosive found” signal. In other embodiments, the system or method uses inferences about other elemental constituents of the ground being examined, sometimes taking as input analyses from prior scans, and providing output indicating the likelihood of the presence of explosives in the region. | 06-05-2014 |
| 20140149435 | BUG LOCALIZATION USING VERSION HISTORY - A method of searching a corpus including a plurality of files includes automatically determining, using a processor, a historical ranking for each file using respective changeset information. Search term(s) of a query are received. A textual ranking is determined for each file using the search term(s) and contents of that file. The historical and textual rankings are combined to provide a result ranking. A data processing system includes a storage system storing the corpus including the plurality of files, a processor configured to determine the result rankings, and a user interface system configured to receive query results from the processor and present them to a user. | 05-29-2014 |
| 20140148508 | C-3 SUBSTITUTED BICYCLOOCTANE BASED HIV PROTEASE INHIBITORS - C3-functionalized-cyclopentanyltetrahydrofuranyl carbamates that inhibit HIV proteolytic enzymes and processes for preparing the compounds are described. Compositions comprising the disclosed compound and methods of using the compounds and/or compositions for treating patients infected with HIV are also described. | 05-29-2014 |
| 20140148349 | Metabolite Biomarkers for the Detection of Esophageal Cancer Using NMR - Methods for the detection and screening of esophageal adenocarcinoma (EAC) patients and for the monitoring of EAC treatment using a panel or panels of small molecule metabolite biomarkers are disclosed. In other aspects, methods for detection and screening for the progression of high-risk conditions (BE and HGD) to EAC and to monitoring treatment using a panel or panels of small molecule metabolite biomarkers are disclosed. The biomarkers are sensitive and specific for the detection of EAC, and can also be used to classify Barrett's esophagus (BE) and high-grade dysplasia (HGD), which are widely regarded as precursors of EAC. | 05-29-2014 |
| 20140144477 | THERMOELECTRIC NANOCRYSTAL COATED GLASS FIBER SENSORS - This disclosure examines using lead telluride nanocrystals as well as other materials suitable for thermoelectric conversion, particularly materials with high Figure of Merit values, as coatings on flexible substrates. This disclosure also examines using flexible substrates with lead telluride nanocrystal coatings as sensors. | 05-29-2014 |
| 20140141480 | METHODS AND SYSTEMS USEFUL FOR DRYING ETHANOL - Mixtures of ethanol and water are dehydrated using starch pearls to adsorb and remove water. Vapor-phase adsorption equilibrium capacities of cassava starch pellets (tapioca pearls) having different particle sizes are disclosed, and tapioca pearl particles are shown to be surprisingly more effective for dehydrating 88 to 97% w/w feed ethanol than corn grits. The adsorption equilibrium curve and BET surface area measurement show that the adsorption capacity of tapioca pearls is a function of surface area available to water molecules. SEM images demonstrate that the particle architecture required for the adsorption and dehydration properties is that of a core-shell configuration with pre-gel starch acting as a central scaffold holding together other particles to the outer layer of the particle. The outer surface area of the pearls, populated with dry starch granules, is the main factor determining the adsorption capacity of the pearls. Tapioca pearls are shown to possess a surprisingly higher adsorption capacity than corn grits of the same particle size. Pearls of 2 mm size in diameter gave 34% higher linear adsorption equilibrium constant (K) than grits of 1.7 mm. | 05-22-2014 |
| 20140141466 | ION GENERATION USING WETTED POROUS MATERIAL - The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples. | 05-22-2014 |
| 20140138540 | SYSTEMS AND METHODS FOR ANALYZING A SAMPLE - The invention generally relates to systems and methods for sample analysis. In certain embodiments, the invention provides systems for analyzing a sample that include an electric source, a vacuum chamber including a conducting member, in which the conducting member is coupled to the electric source, a sample introduction member coupled to the vacuum chamber, and a mass analyzer. The system is configured such that a distal end of the sample introduction member resides within the vacuum chamber and proximate the conducting member, such that an electrical discharge may be produced between the sample introduction member and the conducting member. A neutral gas that has been introduced into the vacuum chamber interacts with the generated discharge, producing ions within the vacuum chamber that are subsequently transferred into the mass analyzer in the vacuum chamber. | 05-22-2014 |
| 20140112866 | POSITRON EMISSION TOMOGRAPHY IMAGING METHOD - Described herein are compositions and methods for diagnosing and/or monitoring pathogenic disease states using positron emission tomography, wherein the pathogenic cells uniquely express, preferentially express, or overexpress vitamin receptors. Also described herein are | 04-24-2014 |
| 20140112413 | DIFFERENTIAL CODEBOOK FOR TEMPORALLY-CORRELATED MISO DUAL-POLARIZATION ANTENNA - A code word selection method performed by a User Equipment (UE) in a wireless communication system is provided. The method includes generating a rotation matrix using previously selected codeword; generating a new differential code book using the rotation matrix and a differential code book; selecting a code word from the new differential code book; and performing data transmission using the selected code word. | 04-24-2014 |
| 20140112272 | METHOD AND APPARATUS FOR USING CHANNEL OUTPUT FEEDBACK IN MULTI USER WIRELESS SYSTEMS AND HYBRID-ARQ - A method and apparatus for transmitting and receiving a signal using a channel output feedback in a wireless communication system and Hybrid-Automatic Repeat Request (ARQ) are provided. The method and apparatus include a transmitter configured to transmit to a base station and a first packet on a precoder received from the base station. A receiver configured to receive, from the base station, a Channel Output Feedback (COF) of the transmitted first packet and information for transmitting a second packet. A controller configured to prepare a variant of the second packet using the COF and the received information for transmitting the second packet, and to control to transmit the prepared variant to the base station. | 04-24-2014 |
| 20140107944 | OPTICAL CHEMICAL CLASSIFICATION - A method for measuring a sample to identify a chemical includes receiving respective spectra for each of a plurality of chemicals. Using a processor, a plurality of binary mathematical filters are computed using the received spectra. A spatial light modulator is adjusted according to a selected mathematical filter. Light that has interacted with the sample is dispersed over the surface of the spatial light modulator, so that the spatial light modulator provides light at wavelengths corresponding to the selected mathematical filter. The light provided by the spatial light modulator is measured to provide a score corresponding to the selected mathematical filter. Filter scores are combined to determine a chemical amount. The processor can operate detection apparatus having a light source, an objective for focusing source light onto the sample, a spatial light modulator, and a detector for detecting the modulator output. | 04-17-2014 |
| 20140099170 | Integrated Laser Material Processing Cell - An integrated laser material processing cell allowing laser-assisted machining to be used in conjunction with directed material deposition in a single setup, achieving greater geometric accuracy and better surface finish than currently possible in existing laser freeform fabrication techniques. The integration of these two processes takes advantage of their common use of laser beam heat to process materials. The cell involves a multi-axis laser-assisted milling machine having a work spindle, a laser emitter, and means for positioning the emitter with respect to the spindle so as to direct a laser beam onto a localized area of a work piece in proximity to a cutting tool mounted in the spindle. A powder delivery nozzle mounted on the machine and positioned adjacent to the emitter delivers powder to a deposition zone in the path of the beam, such that material deposition and laser-assisted milling may be performed substantially simultaneously in a single workspace. | 04-10-2014 |
| 20140088379 | WIRELESSLY-POWERED IMPLANTABLE EMG RECORDING SYSTEM - Apparatus and methods for the measurement and transmission of data pertaining to the tissue of an animal. In one embodiment, there is an implantable device that is wirelessly powered and also wirelessly transmits data. Preferably, the implant measures neuromuscular activity. | 03-27-2014 |
| 20140080977 | HYDROPHILIZED ANTIMICROBIAL POLYMERS - A bactericidal or antimicrobial polymeric composition includes a hydrophilic first comonomer copolymerized to a second comonomer to produce a polymeric composition that is more hydrophilic or more bactericidal or antimicrobial in an aqueous solution than either of the comonomers alone. Methods for identifying bactericidal or antimicrobial polymers, methods for rendering materials bactericidal or antimicrobial, and methods for using bactericidal or antimicrobial compositions to kill or reduce bacterial or microbial growth are also described. Applications for the inventive compositions include their use in catheters, stents, medical devices, contact lenses; root canal fillers; fibers; paper; and/or wound dressing. | 03-20-2014 |
| 20140076194 | ANTIFOULING BY ADHESION SUPPRESSION - The disclosure described herein includes antifouling compositions, methods of antifouling by adhesion suppression and methods of selecting an antifouling composition which suppresses marine animal adhesion or reduces the strength of marine animal adhesion by reducing or quenching the oxidative adhesion chemistry of the marine animal. | 03-20-2014 |
| 20140073763 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING - Described herein are prostate specific membrane antigen (PSMA) binding conjugates that are useful for delivering therapeutic, diagnostic and imaging agents. Also described herein are pharmaceutical composition containing them and methods of using the conjugates and compositions. Also described are processes for manufacture of the conjugates and the compositions containing them. | 03-13-2014 |
| 20140073734 | DYNAMIC LOAD-ABSORBING MATERIALS AND ARTICLES - A compound for protection of an object from a blast or shock wave. The compound include a matrix material and at least a first and second sets of inclusions in the matrix material that differ in size, quantity, shape and/or composition in a direction through the impact-absorbing material, the combination of which contributes to the ability of the material to exhibit at least one property that changes as the inclusions are deformed in response to a blast or shock wave. | 03-13-2014 |
| 20140066488 | Inhibitors of Memapsin 2 Cleavage for the Treatment of Alzheimer's Disease - Proteases such as memapsin 2 are important enzymes, playing roles in a variety of diseases including Alzheimer's Disease. The inventors have developed inhibitors of memapsin 2 and methods of use therefore in the treatment of disease. | 03-06-2014 |
| 20140065066 | IMAGING AND THERAPEUTIC METHOD USING MONOCYTES - The invention relates to a method of treating or diagnosing a disease state mediated by monocytes. The method utilizes a composition comprising a conjugate or complex of the general formula | 03-06-2014 |
| 20140060607 | FLEXIBLE POLYMER-BASED THERMOELECTRIC MATERIALS AND FABRICS INCORPORATING THE SAME - Thermoelectric materials and flexible polymer-based thermoelectric materials that may be applied to fabrics for use as personal cooling/heating clothes and portable power source. | 03-06-2014 |
| 20140060506 | OXYGEN FRACTION ESTIMATION FOR DIESEL ENGINES UTILIZING VARIABLE INTAKE VALVE ACTUATION - A physically-based, generalizable method to estimate the in-cylinder oxygen fraction from production viable measurements or estimates of exhaust oxygen fraction, fresh air flow, charge flow, fuel flow, turbine flow and EGR flow. The oxygen fraction estimates can be sensitive to errors in the EGR and turbine flow, and in other embodiments, a high-gain observer is implemented to improve the estimate of EGR flow. The observer is applicable to engines utilizing high pressure cooled exhaust gas recirculation, variable geometry turbocharging and flexible intake valve actuation as well as other engines. | 03-06-2014 |
| 20140057289 | Micro-Fluidic System Using Micro-Apertures for High Throughput Detection of Cells - A microfluidic detection system for micrometer-sized entities, such as biological cells, includes a detector component incorporating a plate with a plurality of opening, the plate separating two chambers, one in communication with a fluid source containing target entities bound to magnetic beads. The openings are sized to always permit passage of the magnetic beads therethrough into a lower one of the chambers and are further sized to always prevent passage of the target entities from the upper one of the chambers. The detector component further includes a magnet positioned to pull unbound magnetic beads through the openings and to capture target entities bound to magnetic beads on the surface of the plate. In a further feature, the microfluidic detection system is configured to pass target molecules through the plate to be bound to a functionalized surface of the lower chamber. | 02-27-2014 |
| 20140056809 | TREATMENT AND DIAGNOSIS OF MACROPHAGE MEDIATED DISEASE - The invention relates to a method of treating or monitoring/diagnosing a disease state mediated by activated macrophages. The method comprises the step of administering to a patient suffering from a macrophage mediated disease state an effective amount of a composition comprising a conjugate or complex of the general formula | 02-27-2014 |
| 20140051180 | SYNCHRONIZATION OF ION GENERATION WITH CYCLING OF A DISCONTINUOUS ATMOSPHERIC INTERFACE - The invention generally relates to methods and devices for synchronization of ion generation with cycling of a discontinuous atmospheric interface. In certain embodiments, the invention provides a system for analyzing a sample that includes a mass spectrometry probe that generates sample ions, a discontinuous atmospheric interface, and a mass analyzer, in which the system is configured such that ion formation is synchronized with cycling of the discontinuous atmospheric interface. | 02-20-2014 |
| 20140050655 | SYNTHESIS OF METAL OXIDE-BASED THERMOELECTRIC MATERIALS FOR HIGH TEMPERATURE APPLICATIONS - Nanowire synthesis and one dimensional nanowire synthesis of titanates and cobaltates. Exemplary titanates and cobaltates that are fabricated and discussed include, without limitation, strontium titanate (SrTiO | 02-20-2014 |
| 20140049613 | FIGURE-GROUND ORGANIZATION OF 3-D SCENES - Systems and methods for processing a pair of 2-D images are described. In one example, a stereoscopic set of images is converted into a collection of regions that represent individual 3-D objects in the pair of images. In one embodiment, the system recovers the 3-D point P for each point p that appears in both images. It estimates the 3-D orientation of the floor plane, and the image capture planes and their height from the floor. The system then identifies the collection B of points P that do not represent points on the floor and generates a projection C of B onto a plane parallel to the floor. It blurs the projection C and identifies peaks in the blurred image, then fits symmetric figures to the points in C around the identified peaks. The system projects the 3-D figures associated with the symmetric figures back onto the 2-D images. | 02-20-2014 |
| 20140048697 | ION GENERATION USING WETTED POROUS MATERIAL - The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples. | 02-20-2014 |
| 20140047922 | WEAK BOND DETECTION - Apparatuses and methods are disclosed for determining whether a structure of bonded layers includes locations where the layers are weakly bonded. Embodiments include evaluating the frequency response of the structure in response to vibrational inputs. Alternate embodiments include evaluating the non-linear response of the structure using a modal analysis. Further embodiments include obtaining the vibrational information with an accelerometer contacting the structure, while additional embodiments include exciting the structure with an impact force, which may be applied at multiple locations on the structure's surface. Still further embodiments include performing a MAC, COMAC, and/or FRF analysis. Still other embodiments include varying the amplitude of the input vibration. Additional embodiments locate the areas of weakened bonding. Still other embodiments include methods and apparatuses for simulating a laminated structure with defective bonding, such as kiss bonding. | 02-20-2014 |
| 20140046196 | MESOSCOPIC TUMOR MICROENVIRONMENT IMAGING WITH IMPROVED CONTRAST - An apparatus and method of mesoscopic imaging which provide improved contrast to changes in tumor microenvironments are disclosed. The apparatus includes a light which illuminates tissue in vivo, a spectrometer which varies at least one parameter of the light, and optics which transmit light backscattered from the tissue. The optics comprise any one of (i) a small aperture 4-focal length (4-f) lens system within an angular cone of 2°-5°, (ii) a telecentric lens, and (iii) an anti-scatter grid and a camera lens. | 02-13-2014 |
| 20140044595 | GENERATION OF MICROBIOCIDE INSIDE A PACKAGE UTILIZING A CONTROLLED GAS COMPOSITION - An apparatus and method of producing an atmospheric non-equilibrium plasma (ANEP) in a sealed container having a selected working gas and an object to be treated is described. A variety of working gas mixtures including air, O | 02-13-2014 |
| 20140018999 | EXTENDED SMART DIAGNOSTIC CLEAT - Methods and apparatus for diagnosing the condition of a vehicle. Some embodiments include providing an input to a vehicle suspension similar to an impact, and then measuring the response of the vehicle as it drives over an instrumented member. The motion of the instrumented member is recorded and corrected, and in some embodiments a fault index is calculated. The fault index can be displayed to a user to indicate a maintenance condition of the vehicles, such as a worn or broken component. | 01-16-2014 |
| 20140017113 | LARGE STRAIN EXTRUSION MACHINING PROCESSES AND BULK FORMS PRODUCED THEREFROM - Processes by which bulk forms can be produced in a single continuous operation, as opposed to multi-stage deformation processes that involve a series of separate and discrete deformation operations or stages. Such processes generally entail deforming a solid body using a large-strain extrusion machining technique and deformation conditions that obtain a predetermined crystallographic texture in the continuous bulk form that differs from the crystallographic texture of the solid body. | 01-16-2014 |
| 20140014171 | HIGH OPTICAL TRANSPARENT TWO-DIMENSIONAL ELECTRONIC CONDUCTING SYSTEM AND PROCESS FOR GENERATING SAME - Hybrid transparent conducting materials are disclosed with combine a polycrystalline film and conductive nanostructures, in which the polycrystalline film is “percolation doped” with the conductive nanostructures. The polycrystalline film preferably is a single atomic layer thickness of polycrystalline graphene, and conductive nanostructures preferably are silver nanowires. | 01-16-2014 |
| 20140008532 | ION GENERATION USING WETTED POROUS MATERIAL - The invention generally relates to systems and methods for mass spectrometry analysis of samples. In certain embodiments, the invention provides a mass spectrometry probe including at least one porous material connected to a high voltage source, in which the porous material is discrete from a flow of solvent. | 01-09-2014 |
| 20140008529 | ION GENERATION USING WETTED POROUS MATERIAL - The invention generally relates to systems and methods for mass spectrometry analysis of samples. In certain embodiments, the invention provides a mass spectrometry probe including at least one porous material connected to a high voltage source, in which the porous material is discrete from a flow of solvent. | 01-09-2014 |
| 20140003939 | LOAD SHAPE CONTROL OF WIND TURBINES | 01-02-2014 |
| 20130345424 | COMPOSITIONS AND USES THEREOF TO AMELIORATE PAIN - Hydrazinopyridazines, fused hydrazinopyridazines, phenylethylhydrazines, or combinations thereof, compositions comprising hydrazinopyridazines, fused hydrazinopyridazines, phenylethylhydrazines, or combinations thereof, and methods for using them for the treatment of pain are described. | 12-26-2013 |
| 20130344610 | SYSTEMS AND METHODS FOR SAMPLE ANALYSIS - The invention generally relates to systems and methods for sample analysis. In certain embodiments, the invention provides a system for analyzing a sample that includes a probe including a material connected to a high voltage source, a device for generating a heated gas, and a mass analyzer. | 12-26-2013 |
| 20130338380 | PROCESSES AND INTERMEDIATES FOR PREPARING SUBSTITUTED HEXAHYDROFURO [2,3-b] FURANS - The invention described herein pertains to processes and compounds useful in the preparation of bis-tetrahydrofurans. The invention described herein also pertains to compounds useful for treating HIV infections. | 12-19-2013 |
| 20130337075 | NANOMEDICINES FOR EARLY NERVE REPAIR - The present disclosure describes hydrophobically modified nanoparticles and polymeric nanostructures that can be utilized to for the treatment of neuronal injury or neuronal disease in an affected patient, along with methods of forming and using the nanoparticles and nanostructures. Furthermore, the nanoparticles and nanostructures are designed as “dual action” compositions to treat neuronal injury and neuronal disease via repair of damaged membrane and suppression of intracellular inflammation. | 12-19-2013 |
| 20130336899 | ANTIMICROBIAL FORMULATIONS THAT AID IN WOUND HEALING - The invention discloses compositions and formulations for the treatment of clean or infected wounds, some of the inventive formulations can be used to reduce or eliminate microbial contamination from surfaces such as skin, and inanimate objects such as countertops, cooking utensils, medical devices, cookware, food, grooming aids and agricultural biocides, and the like. Some of these compositions and formulations are well suited for use in wound dressings. Some of the formulation can kill and/or inhibit the growth of pathogenic bacteria, fungi, spores and viruses. The formulations comprise a compound such as an osmoticum in high enough concentration to create an osmotic gradient and at least one compound that acts to comprise the integrity of a microorganism's membrane or cell wall. These formulations may optimally include at least one agent that thickens the formulations. In some aspects the formulation is in the form of an emulsion. | 12-19-2013 |
| 20130335173 | TUNABLE CAVITY RESONATOR - A tunable cavity resonator includes a housing, a post, and a controllably variable capacitive coupling. The housing defines an interior and has at least one side wall, a first end, and a second end. The post is located within the interior and extends from the first end to the second end. The post and the housing define a resonating cavity. The controllably variable capacitive coupling is disposed in the housing. | 12-19-2013 |
| 20130335094 | VIBRATORY ANALYSIS OF BATTERIES - Methods and apparatuses for determining the charge of a battery are disclosed. Embodiments include determining the charge in batteries that exhibit mass diffusion during charging or discharging, such as by evaluating the response of the battery to vibration. Alternate embodiments include evaluating the amplitude response of the battery and the phase shift response of the battery. Still other embodiment include evaluating the H | 12-19-2013 |
| 20130331450 | CLASS II HMG-COA REDUCTASE INHIBITORS AND METHODS OF USE - Disclosed are compositions and methods for treating bacterial infections. | 12-12-2013 |
| 20130330782 | LIQUEFACTION BIOMASS PROCESSING WITH HEAT RECOVERY - Described are processes that include the non-enzymatic, hydrolytic liquefaction of lignocellulosic biomass to form digest slurries and heat recovery from such digest slurries. Due to enhanced flow properties of the digest slurries such heat recovery can be efficiently conducted in spiral, plate and frame or other heat exchanger designs, with the recovered heat going to unit operations of the process such as heating incoming pretreatment media for the liquefaction. Processes can also involve additional hydrolytic digestion of some or all of the initial slurry components with enzyme and/or additional heat recovery from the initial slurry by direct contact heat exchange in which a portion of the digest slurry liquids is flashed to vapor and that vapor is condensed onto incoming lignocellulosic biomass to the process. Processes as described can be integrated into ethanol manufacture by fermentation of sugars from the digested compositions. | 12-12-2013 |
| 20130323311 | COLLAGEN-TARGETED NANOPARTICLES - This invention relates to compositions comprising collagen binding peptides coupled to nanoparticles. The invention also relates to a method of imaging a collagenous matrix using a composition comprising collagen binding peptides coupled to nanoparticles. | 12-05-2013 |
| 20130312127 | EFFICIENT STERILIZATION OF FISH BY DISRUPTION OF GERM CELL DEVELOPMENT - Methods of disrupting germ cell migration and development in a fish embryo by inducing targeted expression of Sdf-1 a or Lif and disruption of the Sdf-1 a gradient or a Lif signaling pathway in the fish embryo have been developed. Plasmid constructs containing a gene encoding Sdf-1 a or Lif and a gene encoding a signaling sequence for targeted expression of Sdf-1 a or Lif have been generated. The plasmids will be administered to a fish or a population of fish to reproductively sterilize the population with efficacy of up to 100%. Transgenic fish of this invention are reproductively incompetent of genetically contaminating a wild fish population. | 11-21-2013 |
| 20130295601 | Systems and Methods for Testing Drugs and Drug Delivery Systems - A system is provided that simulates the in vivo micro-environment of three-dimensional cellular structures or bodies, such as tumors. The system simulates the pressure gradients and fluid flows of the vascular and lymphatic systems as well as the interstitial and capillary transport mechanisms between the 3D cellular structure and the vascular and lymphatic systems. The system can be used to introduce drugs or drug delivery carriers to a tumor, for example, to assess the uptake capability and effect on the tumor. The system maintains the viability of the tumor cells for a sufficiently long period of time to permit testing of several different drugs and/or delivery carriers. | 11-07-2013 |
| 20130275054 | SYSTEM AND METHOD OF EXTENDING THE LINEAR DYNAMIC RANGE OF EVENT COUNTING - A method and apparatus for photon, ion or particle counting described that provides seven orders of magnitude of linear dynamic range (LDR) for a single detector. By explicitly considering the log-normal probability distribution in voltage transients as a function of the number of photons, ions or particles present, the binomial distribution of observed counts for a given threshold, the mean number of photons, ions or particles can be determined well beyond the conventional limit. | 10-17-2013 |
| 20130267766 | METHOD AND SYSTEM FOR TRAINING VOICE PATTERNS - One example embodiment of the present disclosure includes method and system to improve communication comprising an assembly fixedly positioned during use in close proximity to a user's ear. The assembly includes an accelerometer to detect the initiation and duration of the user's speech and an output presentation system. The output presentation system comprises a non-occlusive ear fitting that presents unintelligible noise that is unrelated to the sound-frequency or intonation of the user's current speech. The unintelligible noise is presented to the patient at a level less than 85 dB. The system further comprises a control arrangement to maintain presentation of the noise substantially throughout the detected duration of the user's speech, but substantially not at other times. | 10-10-2013 |
| 20130267522 | METHODS FOR TREATING CANCER - The invention relates to methods and uses for the treatment of a cancer. In particular, the invention relates to the use of a folate-vinca conjugate to treat urinary bladder cancer (e.g., invasive transitional cell carcinoma (InvTCC)). | 10-10-2013 |
| 20130261710 | BLOCK COPOLYMER (BCP) ENCAPSULATED NANOPARTICLES AND METHODS OF USE THEREOF - This invention provides block copolymer (BCP) encapsulated nanoparticles. The BCP-encapsulated nanoparticles are used in methods for targeting a tumor, in methods of imaging a tumor and in methods of treating cancer including hyperthermia of tumors. This invention further provides processes for preparation of BCP-encapsulated nanoparticles. | 10-03-2013 |
| 20130259235 | KEY AGREEMENT IN WIRELESS NETWORKS WITH ACTIVE ADVERSARIES - A network and related methods for transmitting processes in a network secretly and securely is described. The network use keys, through path-key establishment and a key pool bootstrapping, to ensure that packets are transmitted and received properly and secretly in the presence of one or more adversarial nodes. | 10-03-2013 |
| 20130254636 | SYSTEM ON CHIP AND METHOD FOR CRYPTOGRAPHY USING A PHYSICALLY UNCLONABLE FUNCTION - A system and method for performing cryptographic functions in hardware using read-N keys comprising a cryptographic core, seed register, physically unclonable function (PUF), an error-correction core, a decryption register, and an encryption register. The PUF configured to receive a seed value as an input to generate a key as an output. The error-correction core configured to transmit the key to the cryptographic core. The encryption register and decryption register configured to receive the seed value and the output. The system, a PUF ROK, configured to generate keys that are used N times to perform cryptographic functions. | 09-26-2013 |
| 20130253037 | AURORA A KINASE EFFECTORS - Two proteins (PHLDA1 and LIMK2) have been identified as direct targets of Aurora A kinase activity. PHLDA1 downregulation and Aurora A upregulation are strong predictors of poor prognosis for breast cancer patients. In accordance with one embodiment a method of detecting, prognosing and monitoring the presence/progression of cancer, and more specifically breast or prostate cancer, is provided. In one embodiment the method comprises the step of analyzing a biological sample from a patient to detect and/or quantitate the presence of Aurora A, PHLDA1 or LIMK2 amino acid sequences. In one embodiment a method of treating cancer is provided comprising the administration of therapies that enhance the activity of PHLDA1 and/or decrease the activity of LIMK2. | 09-26-2013 |
| 20130231343 | COMPOUNDS AND METHODS FOR TREATING MULTIPLE SCLEROSIS - The invention described herein pertains to the treatment of multiple sclerosis. In particular, the invention described herein pertains to the treatment of multiple sclerosis using compounds that modulate the action of acrolein. | 09-05-2013 |
| 20130230584 | TREATING BLADDER TUMOR CELLS USING FIBRONECTIN ATTACHMENT PROTEIN AS A TARGET - Composition and methods are disclosed for utilizing micro-aggregation of FAP-containing complexes to promote their fast internalization. This approach allows the uptake of cytotoxic cargo coupled to either FAP-Antibodies or FAP-liposome complexes by tumor bladder cells. Importantly, this approach is efficient even under serum-free conditions such as the ones found in the lumen of the bladder. | 09-05-2013 |
| 20130227746 | METHODS AND COMPOSITIONS TO REGULATE PLANT TRANSFORMATION SUSCEPTIBILITY - A genetic screen for | 08-29-2013 |
| 20130226469 | GATE-FREE FLOW CYTOMETRY DATA ANALYSIS - Systems, methods, and computer-readable media for determining parameters are provided, as are methods for determining differences in one or more biological response(s) by cell(s) to factor(s). Distances or difference scores are automatically calculated between test data and reference data from a flow cytometer. | 08-29-2013 |
| 20130225863 | Procedures for the Synthesis of Ethylenediamine Bisborane and Ammonia Borane - A method for synthesizing ammonia borane includes (a) preparing a reaction mixture in one or more solvents, the reaction mixture containing sodium borohydride, at least one ammonium salt, and ammonia; and (b) incubating the reaction mixture at temperatures between about 0° C. to about room temperature in an ambient air environment under conditions sufficient to form ammonia borane. Methods for synthesizing ethylenediamine bisborane, and methods for dehydrogenation of ethylenediamine bisborane are also described. | 08-29-2013 |
| 20130224881 | POLYROTAXANES AND USES THEREOF - A polyrotaxane containing an affinity binding group has been designed and prepared. The polyrotaxane of the invention can be used for characterization and determination of the three-dimensional structures of biological molecules, such as proteins. | 08-29-2013 |
| 20130210671 | IMMUNOREACTIVE ANTIGENS OF MYCOPLASMA HEAMOFELIS AND DIAGNOSTIC IMMUNOASSAY - Compositions for use in diagnostic screens for | 08-15-2013 |
| 20130204591 | Method of Modeling Cloud Point of a Mixture of Fatty Acid Methyl Esters using a Modified UNIFAC Model and a System Therefor - A method for predicting onset of liquid phase to solid phase transition of a mixture including a plurality of fatty acid methyl esters components. The method includes identifying chemical and molecular structure of each component of the mixture, calculating activity coefficients for each component in a liquid phase and a solid phase, calculating chemical potential for each component in the liquid phase and in the solid phase at a predetermined temperature and a predetermined pressure, and calculating the cloud point of the mixture. A system for carrying out the method is also disclosed. | 08-08-2013 |
| 20130204581 | AUTOMATIC MONITORING OF INSECT POPULATIONS - Illustrative embodiments of integrated pest management (IPM) systems and electronic insect monitoring devices (EIMDs) are disclosed. In some embodiments, the EIMDs may each comprise a lure for attracting at least one target insect species, one or more sensors that generate one or more output signals in response to an insect approaching the lure, and an electronic controller configured to determine if the insect approaching the lure belongs to the at least one target insect species using the one or more output signals. In some embodiments, the IPM system may comprise a plurality of EIMDs configured to communicate over a wireless network shared by the plurality of EIMDs. | 08-08-2013 |
| 20130203071 | PEPTIDE APTAMERS FOR MANIPULATING PROTEIN FUNCTION - Peptide aptamers and the methods to produce cassettes including the aptamers and manipulating them, are described. The peptide aptamer cassettes are useful to, e.g., inhibit protein function such as proteins necessary for the transformation of plants, or to replicate cells. | 08-08-2013 |
