PROTEUS DIGITAL HEALTH, INC. Patent applications |
Patent application number | Title | Published |
20150112243 | Integrated Ingestible Event Marker System with Pharmaceutical Product - A system and method are provided for securing an ingestible electronic device to a pharmaceutical product without damaging the ingestible electronic device. The product includes the ingestible electronic device being placed on the product in accordance with one aspect of the present invention. In accordance with another aspect of the present invention, the ingestible electronic device is placed inside the product. Various embodiments are disclosed in accordance with the present invention for protecting and/or coating of the electronic marker as well as securing the ingestible electronic device onto the product. | 04-23-2015 |
20140334575 | Active Signal Processing Personal Health Signal Receivers - The invention provides a receiver associated with a body, e.g., located inside or within close proximity to a body, configured to receive and decode a signal from an in vivo transmitter which located inside the body. Signal receivers of the invention provide for accurate signal decoding of a low-level signal, even in the presence of significant noise, using a small-scale chip, e.g., where the chip consumes very low power. Also provided are systems that include the receivers, as well as methods of using the same. | 11-13-2014 |
20140309504 | In-Body Device with Virtual Dipole Signal Amplification - Virtual dipole signal amplification for in-body devices, such as implantable and ingestible devices, is provided. Aspects of the in-body deployable antennas of the invention include antennas configured to go from a first configuration to a second configuration following placement in a living body, e.g., via ingestion or implantation. Embodiments of the in-body devices are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention. | 10-16-2014 |
20140236077 | Body-Associated Receiver and Method - Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems. | 08-21-2014 |
20140206976 | Wearable Personal Body Associated Device with Various Physical Configurations - A body associated device comprises a housing, an adhesive layer configured to be applied to a body of a living subject, and at least one standoff located between the housing and the adhesive layer. An electronic module may be located within the housing of the body associated device. A personal communication system comprises a body associated device including an electronic module and further comprises a feedback portion coupled to the housing and to the electronic module. The feedback portion is configured to communicate information between the living subject and the body associated device. An external local node is operative to provide at least one of transmit communications to and receive communications from the body associated device. | 07-24-2014 |
20140180202 | Ingestible Therapy Activator System and Method - An ingestible therapy activator system and method are provided. In one aspect, the ingestible therapy activator includes an ingestible device having an effector module to send an effector instruction and a responder module associated with a therapeutic device. The responder module may receive and process the effector instruction, resulting in a response by the therapeutic device. Examples of responses by therapeutic device include activating a therapy, deactivating a therapy, modulating a therapy, and discontinuing a therapy. | 06-26-2014 |
20140066734 | Apparatus and Method for Measuring Biochemical Parameters - In a first embodiment, electrodes are coupled to a surface at first, second, and third locations, the first location being further from the third location than from the second location. Impedance is measured at distinct frequencies between pairs of the electrodes. As a result, impedance is measured at differing regions below the surface, one region being deeper below the surface than the other region. In a second embodiment, a microfluidic device carries out an analysis. The analysis may be within a flexible patch adhered to a surface, or may be in a solid device implanted in a body of liquid surrounded by tissue. The analysis may involve pumping a fluid or may involve drawing an analyte electrophoretically through a microfluidic channel. | 03-06-2014 |
20140066726 | Biological Sample Collection Device and System - A biological sample collection device includes a top cover plate, a bottom portion attached to the top cover plate, the bottom portion comprising a remotely-analyzable biological sample collection portion to collect a biological sample from a body of a subject. The biological sample is to be analyzed at a remote processing facility at a later time. A fastening portion is provided on the bottom portion to affix the remotely-analyzable biological sample collection device to the body of the subject. A real time clock is coupled to the top cover plate and a memory is coupled to the top cover plate and electrically coupled to the real time clock. The remotely-analyzable biological sample collection device may further include a processing unit, at least two electrodes coupled to the processing unit, and a transbody conductive communication module. Additionally, a remotely-analyzable biological sample collection device communication system includes a wireless communication device configured to communicate with a communication device external to the patient. | 03-06-2014 |
20140051965 | Implantable Zero-Wire Communications System - The present invention provides implantable systems that communicate wirelessly with each other using a unique format that enables devices configurations and applications heretofore not possible. Embodiments of the present invention provide communication apparatuses and methods for exchanging information with implantable medical devices. In some embodiments, two implantable devices communicate with each other using quasi-electrostatic signal transmission in a long wavelength/low frequency electromagnetic band, with the patient's body acting as a conductive medium. | 02-20-2014 |
20140051946 | RE-WEARABLE WIRELESS DEVICE - A re-wearable wireless device includes a reusable component to be secured to a disposable component. The reusable component includes a sensor interface to receive signals from an electrode secured to a living subject and monitors physiological and physical parameters associated with the living subject and a cellular wireless communication circuit. An adhesive base the device includes a first adhesive layer and a second adhesive layer partially covering the first adhesive layer around a perimeter thereof, where the first and second adhesive layers include different adhesives. A method of establishing a link between two wireless devices is also disclosed, where a first wireless device with an insignia representing a communication channel address identification is provided. An image of the insignia is captured with a mobile telephone computing device comprising an image sensor. The captured image is processed to extract the communication channel address identification represented by the insignia. | 02-20-2014 |
20140046147 | Pharmaceutical Dosages Delivery System - Pharmaceutical delivery systems for delivering dosages according to the present invention include a carrier component and a cap configured to seal an internal volume of the carrier component, wherein the cap includes a device that produces a unique current signature. Dosages prepared to be delivered according to embodiments of the invention find use in a variety of different applications, including clinical trials. | 02-13-2014 |
20140017995 | Multi-Mode Communication Ingestible Event Markers and Systems, and Methods of Using the Same - Aspects of the invention include multi-mode communication ingestible event marker devices. Ingestible event marker devices of the invention include an ingestible component comprising a conductive communication module and at least one additional non-conductive communication module. The non-conductive communication module may be integrated with the ingestible component or at least a portion or all of the non-conductive communication module may be associated with a packaging component of the ingestible event marker device. Additional aspects of the invention include systems that include the devices and one or more receivers, as well as methods of using the same. | 01-16-2014 |
20140009262 | PERSONAL AUTHENTICATION APPARATUS SYSTEM AND METHOD - A target authentication device includes an electrode to detect an electrical signal associated with a user of the device. The electrical signal represents an authentication code for the device. An authentication receiver module is coupled to the electrode. The module receives the electrical signal from the electrode and determines whether the electrical signal matches a predetermined criterion to authenticate the identity of the user based on the electrical signal. An authentication module is also disclosed. The authentication module includes one electrode to couple an electrical signal associated with a user to a user of a target authentication device, the electrical signal represents an authentication code for the device. An authentication transmission module is coupled to the electrode. The authentication transmission module transmits the electrical signal from the electrode. A method of authenticating the identity of a user of a target authentication device also is disclosed. | 01-09-2014 |
20140004492 | System, Method, and Article to Prompt Behavior Change | 01-02-2014 |
20130338628 | Probablistic Pharmacokinetic and Pharmacodynamic Modeling - The subject matter disclosed herein provides a response to a dose of a substance and/or controls the administration of the dose. In one aspect, there is provided a system. The system may include a processor and at least one memory configured to provide a response determinator. The response determinator may receive therapeutic and wellness data. Moreover, the response determinator may determine a response based on the received therapeutic and wellness data. The response may represent a reaction to a substance integrated with an ingestible event marker. The determined response may be provided to, for example, a therapy controller. Related systems, methods, and articles of manufacture are also described. | 12-19-2013 |
20130338452 | Low Profile Antenna for in Body Device - Low profile antennas for ingestible devices, such as ingestible event markers, are provided. Aspects of the ingestible devices of the invention include low profile signal transmission antennas configured such that they are flexible or degrade after use, allowing the antenna and attached components to pass easily through the body. Embodiments of the low profile antennas are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention. | 12-19-2013 |
20130328416 | Wireless Energy Sources for Integrated Circuits - A system comprising a control device and a wireless energy source electrically coupled to the control device is disclosed. The wireless energy source comprises an energy harvester to receive energy at an input thereof in one form and to convert the energy into a voltage potential difference to energize the control device. Also disclosed, is the system further comprising a partial power source. Also disclosed, is the system further comprising a power source. | 12-12-2013 |
20130238647 | Diagnostic System and Method - Disclosed are an apparatus and system for providing diagnosis information to a requestor. A request module receives information related to a request from the requestor for diagnosis and to facilitate communication to at least one expert resource. A receive module receives at least one response to the request for diagnoses from the at least one expert resource. A select module in communication with the receive module analyzes the at least one response and, based on the analysis, communicates information to at least one predetermined destination. A method is disclosed where a request module receives a request, a receive module receives a plurality of responses to the request and from the plurality of responses, a select module selects a subset of responses and communicates the subset of responses to a predetermined destination. | 09-12-2013 |
20130231188 | Networked Application with a Physiological Detector - The present invention provides receiving devices and method for use with gaming pursuits, including, in one aspect, a plurality of receivers to communicate physiologic data, at least one hub to receive the physiologic data, and a gaming module to receive, directly or indirectly, the physiologic data from the hub. | 09-05-2013 |
20130223028 | HYBRID HOUSING FOR IMPLANTABLE MEDICAL DEVICE - Apparatuses and methods for hybrid housings as well as hybrid housing based implantable medical devices are provided. A hybrid housing comprises a ceramic substrate, a bonding structure formed on the periphery of the ceramic substrate, and a biocompatible metal cap coupled to the ceramic substrate using the bonding structure to form a hermetically sealed enclosure. One or more electronic elements may be formed within the hermetically sealed enclosure, and the electronic elements may be stably associated with the ceramic substrate. | 08-29-2013 |
20130217982 | State Characterization Based on Multi-variate Data Fusion Techniques - The ingestible event marker data framework provides a uniform, comprehensive framework to enable various functions and utilities related to ingestible event marker data (IEM data). Included are a receiver adapted to be associated with a body of an individual, the receiver configured to receive IEM data; a hub to receive the IEM data; and at least one IEM data system to receive the data from the hub. Among other information, behavioral data and predictive inferences may be provided. | 08-22-2013 |
20130193950 | Ingestible Circuitry - The present invention provides for safe and reliable electronic circuitry that can be employed in ingestible compositions. The ingestible circuitry of the invention includes a solid support; a conductive element; and an electronic component. Each of the support, conductive element and electronic component are fabricated from an ingestible material. The ingestible circuitry finds use in a variety of different applications, including as components of ingestible identifiers, such as may be found in ingestible event markers, e.g., pharma-informatics enabled pharmaceutical compositions. | 08-01-2013 |
20130172690 | APPARATUS, SYSTEM AND METHOD FOR DETECTION AND DELIVERY OF A MEDICINAL DOSE - An apparatus is disclosed as part of a system for tracking and confirming delivery of a medicinal dose to a user. The apparatus includes a detector. The detector is secured to and communicatively coupled to the user and is capable of detecting a current flow through the user's body. The current flow is produced when the user makes contact with the apparatus. The apparatus includes at least two contact areas connected to a power source where a circuit and, hence, a current path is completed through the user's body as the user makes contact with the apparatus. The current flow is detected by the detector, which is coupled to the user. Also disclosed is an apparatus for tracking and confirming delivery of a medicinal dose to a user where the apparatus includes an acoustic detector. Upon loading the dose into a chamber an acoustic vibration is generated. The vibration is detected and correlated with a current flow that is produced when the user makes contact with the apparatus. The combined event of vibration detection and current flow detection confirms that the dose is loaded and the user is in contact with the apparatus and ready to receive the dose. | 07-04-2013 |
20130144132 | Highly Reliable Ingestible Event Markers and Methods for Using the Same - Ingestible event markers having high reliability are provided. Aspects of the ingestible event markers include a support, a control circuit, a first electrochemical material, a second electrochemical material and a membrane. In addition, the ingestible event markers may include one or more components that impart high reliability to the ingestible event marker. Further, the ingestible event markers may include an active agent. In some aspects, the active agent, such as a pharmaceutically active agent or a diagnostic agent may be associated with the membrane. | 06-06-2013 |
20130096501 | System and Method for Patient Access Port Reporting - A method is disclosed for detecting, by a sensing and data acquisition circuit module, at least one parameter associated with an access port. The method includes wiping at least a portion of an access port, allowing the access port to dry for a predetermined amount of time, accessing the access port with an access device, such as a syringe, and detecting at least one parameter associated with the access port by the sensor and acquisition module. An access port is disclosed that includes a sensor and a data acquisition module for sensing, recording, and providing an alert associated with the detection of the at least one parameter associated with the access port. | 04-18-2013 |
20130073312 | Tracking and Delivery Confirmation of Pharmaceutical Products - A system and method are disclosed that track a deliverable to a user. The system includes an identifier or tag secured to the deliverable, a computer system for interrogating the identifier, and a personal device in communication with the computer system, wherein the personal device is held by the user at the time the user is administered the deliverable to detect the unique identity associated with the identifier device and confirms delivery of the deliverable to the user. The method includes attaching an identifiable tag that produces a unique signature to the deliverable, interrogating the tag at about the time of delivery to the user, and confirming that the user has been administered the deliverable through detecting the identifiable tag. | 03-21-2013 |
20130060102 | Two-Wrist Data Gathering System - Sensing is carried out from locations at considerable remove from the stomach. Cooperating sensor electronics are placed at each of two wrists of the patient. The potential discomfort and inconvenience of an abdominal patch are reduced or eliminated. And alternative power sources become available. | 03-07-2013 |
20130030366 | Miniature Ingestible Device - The present invention discloses multiple approaches to preventing the capsule walls and other material from interfering with the performance of an electronic device once the device is activated by surrounding fluid. In accordance with the teachings of the present invention, a miniature ingestible device (MID) may be created using excipients and films. The MID, in accordance with various aspects of the present invention, will have a coating or laminating surrounding an electronic device and separating and isolating the device from the pharmaceutical product or drug within the capsule once the capsule is ingested as well as from the capsule itself as the capsule walls begin to collapse during the disintegration process. | 01-31-2013 |