Norchip A/S Patent applications |
Patent application number | Title | Published |
20130309658 | METHOD FOR DETECTING HUMAN PAPILLOMAVIRUS mRNA - An in vitro method is provided for screening human female subjects to assess their risk of developing cervical carcinoma which comprises screening the subject for expression of mRNA transcripts from the E6 and optionally the L1 gene of human papillomavirus, wherein subjects positive for expression of L1 and/or E6 mRNA are scored as being at risk of developing cervical carcinoma. Kits for carrying out such methods are also provided. | 11-21-2013 |
20120196280 | MICROFABRICATED DEVICE FOR METERING AN ANALYTE - The present invention relates to a microfabricated device for metering an analyte comprising a nucleic acid sequence into a plurality of parallel reaction chambers for nucleic acid sequence amplification. The present invention further provides a method of metering an analyte into a plurality of parallel reaction units of an integrated microfabricated device. | 08-02-2012 |
20120016593 | METHOD AND APPARATUS FOR WORLDWIDE SREENING FOR HUMAN PAPILLOMA VIRUS - The invention relates to in vitro methods of screening female human subjects for the presence of human papillo mavirus, for example as a marker of cervical epithelial precancer. In particular, the invention provides methods and apparatus which can be used to filter a patient data set of measurements related to multiple HPV types according to the geographical location of the patient under test, so that only those measurements of HPV types which are pre-determined to be relevant for the geographical region in which the patient under test is located are selected for output/display. | 01-19-2012 |
20110275698 | "TEST AND TREAT" STRATEGY FOR TREATING TRANSFORMING HPV INFECTION - The invention is concerned with a “test and treat” method of screening and directly treating female subjects having transforming or abnormal human papillomavirus (HPV) infection. | 11-10-2011 |
20110111386 | CERVICAL CELL COLLECTION METHOD - The present invention relates to sample collection and preservation. More specifically, the invention provides methods for the collection and preservation of at least one nucleic acid molecule in a test sample comprising one or more cells or tissues obtained from the cervix of a subject. | 05-12-2011 |
20100330550 | DETECTION OF HUMAN PAPILLOMAVIRUS - The present invention relates to in vitro methods of screening human subjects for the presence of human papillomavirus (HPV) which exhibits loss of regulation of E6/E7 mRNA expression and loss of replication and/or expression of a stabilized pre-mRNA encoding full length E6 protein. In particular, the invention provides in vitro methods of screening for persistent transforming HPV infection equivalent to persistent cell abnormalities or persistent CIN III lesions, cancer in situ or high-grade squamous intraepithelial lesions (HSIL). The methods are useful in the context of cervical cancer screening. | 12-30-2010 |
20100297754 | DEVICE FOR CARRYING OUT CELL LYSIS AND NUCLEIC ACID EXTRACTION - The present invention provides an integrated lab-on-a-chip device for carrying out a nucleic acid extraction process on a fluid sample containing cells and/or particles, the device comprising: (a) a sample inlet ( | 11-25-2010 |
20090275044 | METHOD FOR DETECTING HUMAN PAPILLOMAVIRUS mRNA - An in vitro method is provided for screening human female subjects to assess their risk of developing cervical carcinoma which comprises screening the subject for expression of mRNA transcripts from the E6 and optionally the L1 gene of human papillomavirus, wherein subjects positive for expression of L1 and/or E6 mRNA are scored as being at risk of developing cervical carcinoma. Kits for carrying out such methods are also provided. | 11-05-2009 |
20090253124 | METHOD FOR DETECTING HUMAN PAPILLOMAVIRUS mRNA - An in vitro method is provided for screening human female subjects to assess their risk of developing cervical carcinoma which comprises screening the subject for expression of mRNA transcripts from the E6 and optionally the L1 gene of human papillomavirus, wherein subjects positive for expression of L1 and/or E6 mRNA are scored as being at risk of developing cervical carcinoma. Kits for carrying out such methods are also provided. | 10-08-2009 |
20080248590 | Device For Carrying Out A Biological Assay - An integrated lab-on-a-chip device for carrying out an assay to detect the presence of a biological molecule in a fluid sample, the device comprising: (a) an inlet for a fluid sample; (b) one or more reaction sites each in fluid communication with the inlet; (c) one or more reagent reservoir systems each containing reagents required for an assay to detect a biological molecule, the reagents being arranged sequentially in each reservoir system in the order in which they are required for the assay and separated from one another by a fluid. | 10-09-2008 |
20080227185 | Diagnostic System for Carrying Out a Nucleic Acid Sequence Amplification and Detection Process - An integrated lab-on-a-chip diagnostic system for carrying out a sample preparation process on a fluid sample containing cells and/or particles, the system comprising: (a) an inlet for a fluid sample; (b) a lysis unit for lysis of cells and/or particles contained in the fluid sample; (c) a nucleic acid extraction unit for extraction of nucleic acids from the cells and/or particles contained in the fluid sample; (d) a reservoir containing a lysis fluid; (e) a reservoir containing an eluent for removing nucleic acids collected in the nucleic acid extraction unit; wherein the sample inlet is in fluid communication with the lysis unit, an optional valve being present to control the flow of fluid therebetween; wherein the lysis unit is in fluid communication with the nucleic acid extraction unit, an optional valve being present to control the flow of fluid therebetween; wherein the reservoir containing the lysis fluid is in fluid communication with the lysis unit, an optional valve being present to control the flow of fluid therebetween; and wherein the reservoir containing the eluent is in fluid communication with the nucleic acid extraction unit, an optional valve being present to control the flow of fluid therebetween. | 09-18-2008 |