NIPPON CHEMIPHAR CO., LTD. Patent applications |
Patent application number | Title | Published |
20160122349 | MORPHINAN DERIVATIVE - The present invention relates to a morphinan derivative represented by the following general formula (I), wherein R | 05-05-2016 |
20150045396 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR GIANT CELL TUMORS OCCURRING IN BONE AND SOFT TISSUE OR FOR CHONDROSARCOMA - The present invention provides a prophylactic or therapeutic agent for giant cell tumors occurring in a bone and soft tissue or for chondrosarcoma, which comprises a non-steroidal anti-inflammatory agent or thiazolidine derivative as an active ingredient, and the like | 02-12-2015 |
20140343015 | MORPHINAN DERIVATIVE - A morphinan derivative represented by the following general formula (I) | 11-20-2014 |
20140148599 | PREVENTIVE OR THERAPEUTIC AGENT FOR PAIN ASSOCIATED WITH HERPES ZOSTER IN ACUTE PHASE | 05-29-2014 |
20140018537 | GPR119 AGONIST - A cyclic amine derivative represented by the formula (II) is a GPR119 agonist, and is used as an agent for treating diabetes. | 01-16-2014 |
20130217734 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA - A compound represented by the following general formula (II) or a salt thereof is used as an activator of PPARĪ“. | 08-22-2013 |
20130184459 | P2X4 RECEPTOR ANTAGONIST - A compound having the following formula (II) or a pharmacologically acceptable salt thereof is used as a P2X | 07-18-2013 |
20130178625 | P 2 X 4 RECEPTOR ANTAGONIST - A compound having the following formula (II) or a pharmacologically acceptable salt thereof is used as a P2X | 07-11-2013 |
20130172550 | P2X4 RECEPTOR ANTAGONIST - A diazepine derivative having the following formula (III) or a pharmacologically acceptable salt thereof is used as A P2X | 07-04-2013 |
20130149715 | G-PROTEIN-CONJUGATED RECEPTOR HAVING ALTERED LIGAND AFFINITY, AND USE THEREOF - A modified G-protein-coupled receptor (GPCR), having modified ligand affinity is provided by binding a G-protein-coupled receptor to a polypeptide consisting of an amino acid sequence of SEQ ID NO: 1. Furthermore, agonists for or antagonists against the modified GPCR are screened using a transformant in which the modified GPCR has been expressed. This makes it possible to provide a technique for analyzing the function of many putative GPCRs whose entities have not been clarified. | 06-13-2013 |
20120270910 | PHARMACEUTICAL CONTAINING PPAR-DELTA AGONIST - Provision of an agent for promoting proliferation of meibomian gland epithelial cells or corneal epithelial cells, and a therapeutic agent for ocular diseases such as meibomian gland dysfunction, dry eye and the like. A preparation containing [3-[2-[4-isopropyl-2-(4-trifluoroethyl)phenyl-5-thiazolyl]ethyl]-5-methyl-1,2-benzisoxazol-6-yl]oxyacetic acid, [4-[3-[2-(4-trifluoromethyl)phenyl-4-isopropyl-5-thiazolyl]propionyl]-2-methylphenoxy]acetic acid or [4-[3-[2-(2-hydroxy-4-chlorophenyl)-5-isopropyl-4-oxazolyl]propionyl]-2-methylphenoxy]acetic acid, or a pharmacologically acceptable salt thereof as an active ingredient is used as an agent for promoting proliferation of meibomian gland epithelial cells or corneal epithelial cells, as well as a therapeutic agent for ocular diseases such as meibomian gland dysfunction, dry eye and the like. | 10-25-2012 |
20120245344 | GPR119 AGONIST - A compound represented by the formula (II) is a GPR119 agonist, and is used as an agent for treating diabetes: | 09-27-2012 |
20110319610 | DIAZEPINEDIONE DERIVATIVE - A diazepinedione derivative represented by the formula (I) or a pharmacologically acceptable salt thereof is used as a P2X | 12-29-2011 |
20110257201 | AGENT FOR OVERCOMING RESISTANCE TO ANTI-CANCER AGENT - An agent comprising, as an active ingredient, a xanthine oxidase inhibitor such as 2-[3-cyano-4-(4-fluorophenoxy)phenyl]-4-hydroxythiazolo[5,4-d]pyrimidine potassium salt, 2-[3-cyano-4-(4-fluorophenoxy)phenyl]thiazolo[5,4-d]pyrimidine, 2-(3-cyano-4-phenoxyphenyl)-4-hydroxythiazolo[5,4-d]pyrimidine, 2-(3-cyano-4-phenoxyphenyl)-4-hydroxythiazolo[5,4-d]pyrimidine potassium salt, 2-(3-cyano-4-phenoxyphenyl)thiazolo[5,4-d]pyrimidine, TMX-67, and FYX-051, which can be used as an agent for overcoming anti-cancer agent resistance. | 10-20-2011 |
20110137032 | GPR119 AGONIST - A cyclic amine derivative represented by the formula (II) is a GPR119 agonist, and is used as an agent for treating diabetes. | 06-09-2011 |
20110092703 | P2X4 RECEPTOR ANTAGONIST | 04-21-2011 |
20110092484 | THERAPEUTIC OR PROPHYLACTIC AGENT FOR CEREBRAL ANEURYSM - [Problems] To provide a medicament which is effective for treatment and prophylaxis of cerebral aneurysms | 04-21-2011 |
20110003993 | SALT OF (2S, 3S) -3- [ [ (1S) -1- ISOBUTOXYMETHYL-3-METHYLBUTYL] CARBAMYL] OXIRANE-2-CARBOXYLIC ACID - The invention relates to purification of (2S,3S)-3-[[(1S)-1-isobutoxymethyl-3-methylbutyl]carbamoyl]oxirane-2-carboxylic acid [hereinafter, referred to as the carboxylic acid] using the salt of the carboxylic acid with an organic amine selected from the group consisting of piperazine, adamantane amines and others. The invention also relates to providing crystalline sodium salt of the carboxylic acid. The sodium salt is usable as a material for preparing medicaments and improved in storage stability, and has the following characteristics:
| 01-06-2011 |
20100331545 | REGULATOR FOR SIGNALING TOLL-LIKE RECEPTOR, WHICH COMPRISES CATHEPSIN INHIBITOR AS ACTIVE INGREDIENT - [Problems] To provide a modulator for signaling of TLR | 12-30-2010 |
20100234399 | AGENT FOR OVERCOMING RESISTANCE TO ANTI-CANCER AGENT - An agent comprising, as an active ingredient, a xanthine oxidase inhibitor such as 2-[3-cyano-4-(4-fluorophenoxy)phenyl]-4-hydroxythiazolo[5,4-d]pyrimidine potassium salt, 2-[3-cyano-4-(4-fluorophenoxy)phenyl]thiazolo[5,4-d]pyrimidine, 2-(3-cyano-4-phenoxyphenyl)-4-hydroxythiazolo[5,4-d]pyrimidine, 2-(3-cyano-4-phenoxyphenyl)-4-hydroxythiazolo[5,4-d]pyrimidine potassium salt, 2-(3-cyano-4-phenoxyphenyl)thiazolo[5,4-d]pyrimidine, TMX-67, and FYX-051, which can be used as an agent for overcoming anti-cancer agent resistance. | 09-16-2010 |
20090312563 | SALT OF (2S, 3S)-3-[[ (1S)-1-ISOBUTOXYMETHYL-3-METHYLBUTYL] CARBAMOYL] OXIRANE-2-CARBOXYLIC ACID - The invention relates to purification of (2S,3S)-3-[[(1S)-1-isobutoxymethyl-3-methylbutyl]carbamoyl]oxirane-2-carboxylic acid [hereinafter, referred to as the carboxylic acid] using the salt of the carboxylic acid with an organic amine selected from the group consisting of piperazine, adamantane amines and others. The invention also relates to providing crystalline sodium salt of the carboxylic acid. The sodium salt is usable as a material for preparing medicaments and improved in storage stability, and has the following characteristics:
| 12-17-2009 |
20090203908 | Activator for Peroxisome Proliferator-Activated Receptor - A compound having the following formula or its salt is used as an activator for PPAR: | 08-13-2009 |
20090149452 | XANTHINE OXIDASE INHIBITOR - A compound represented by the following formula (I) is used as a xanthine oxidase inhibitor: in which R | 06-11-2009 |