| Monash University Patent applications |
| Patent application number | Title | Published |
|---|
| 20150259212 | GRAPHENE-BASED MATERIALS - The present invention relates to graphene-based foam, the graphene-based foam having a structure defined by a three-dimensional network of interconnected and ordered open cells, the open cells being defined by cell walls, the cell walls (i) being formed of graphene sheets, partially reduced graphene oxide sheets, reduced graphene oxide sheets, or a combination thereof, and (ii) having a thickness defined by the thickness of a plurality of graphene sheets, partially reduced graphene oxide sheets, reduced graphene oxide sheets, or a combination thereof. | 09-17-2015 |
| 20150174423 | OPTIMISING CURRENT DIRECTION AND INTENSITY OF TRANSCRANIAL MAGNETIC STIMULATION - A method of optimising transcranial magnetic stimulation is described. An electrical signal is applied to a coil to generate one or more magnetic field pulses for transcranial magnetic stimulation of a target cortical region of a patient. The transcranial magnetic stimulation has stimulation parameters including orientation of the coil relative to the patient and intensity of the magnetic stimulation. At least the orientation of the coil relative to the patient is varied. At different orientations of the coil relative to the patient, neuron activation at the target cortical region is determined by monitoring changes in blood flow and/or blood oxygenation, e.g. using near infra-red spectroscopy. Based on information obtained during the monitoring, one or more optimal coil orientations for the transcranial magnetic stimulation are determined. Apparatus for carrying out the method is also described. | 06-25-2015 |
| 20150150482 | METHOD AND SYSTEM FOR IMAGING - A method for dynamic investigation of a subject lung, the method comprising the steps of: (i) imparting an oscillation to the lung at one or more forcing frequencies so as to elicit a lung response, (ii) sensing the response of the lung simultaneously with the imparting of the oscillation to elicit a lung response, (iii) choosing at least one parameter used in the sensing to define the lung motion associated with the lung response, (iv) comparing one of the chosen parameters at each forcing frequency with the response at the forcing frequency in at least one region of the lung, and (v) recording the comparison of step (iv). | 06-04-2015 |
| 20150108006 | PROCESS AND CATALYST-ELECTROLYTE COMBINATION FOR ELECTROLYSIS - The invention relates to a process for electrolysis comprising a cathode and an anode comprising a catalyst, both the cathode and anode at least partly immersed in an electrolyte, the process characterised in that the electrolyte at least partly inhibits further oxidation of a product formed at the anode. Typically the catalyst comprises one or more metal-(Group VIb) semiconductors, and one or more metal-(GroupVIb))-phosphorous species. | 04-23-2015 |
| 20150018440 | TEMPERATURE-RESPONSIVE POLYMER PARTICLES IN PROTEIN SEPARATION APPLICATIONS - The present invention relates to a method for isolating proteins from a solution containing the proteins. The invention also relates to a method for the chromatographic separation of proteins. The present invention also relates to crosslinked hydroxylic polymer particles functionalized with temperature-responsive copolymer, and to methods of preparing such particles. | 01-15-2015 |
| 20140334710 | PARTICLE IMAGE VELOCIMETRY SUITABLE FOR X-RAY PROJECTION IMAGING - A 2D or 3D velocity field is reconstructed from cross-correlation analysis of image pairs of a sample, without first reconstructing images of the sample spatial structure. The method can be implemented via computer tomographic X-ray particle image velocimetry, using multiple projection angles, with phase contrast images forming dynamic speckle patterns. Estimated cross-correlations may be generated via convolution of a measured autocorrelation function with a velocity probability density function, and the velocity coefficients iteratively optimised to minimise the error between the estimated cross-correlations and the measured cross-correlations. The method may be applied to measure blood flow, and the motion of tissue and organs such as heart and lungs. | 11-13-2014 |
| 20140294969 | Method and formulation for inhalation - This invention relates to drug delivery and in particular to the delivery of biologically active agents in the form of dry powders for inhalation. The invention also relates to methods for preparing such dry powder formulations and methods for their use. | 10-02-2014 |
| 20140286556 | HEART IMAGING METHOD - The present invention relates to imaging of a human or animal heart, particularly imaging of movement of the heart and can be used for imaging function and form in a wide range of research, medical, veterinary and industrial applications. In particular, the present invention provides a method and apparatus for imaging a subject heart, the method including the steps of (1) recording at least one in vivo image of a lung of the subject in one or more regions; (2) applying said at least one in vivo image to a 2D or 3D heart model; and (3) reconstructing a 2D or 3D image field of the subject heart. | 09-25-2014 |
| 20140125292 | LITHIUM ENERGY STORAGE DEVICE - The present invention generally relates to lithium based energy storage devices. According to the present invention there is provided a lithium energy storage device comprising: at least one positive electrode; at least one negative electrode; and an ionic liquid electrolyte comprising an anion, a cation counterion and lithium mobile ions, wherein the anion comprises a nitrogen, boron, phosphorous, arsenic or carbon anionic group having at least one nitrile group coordinated to the nitrogen, boron, phosphorous, arsenic or carbon atom of the anionic group. | 05-08-2014 |
| 20140050795 | BINDER POWDERS - The present disclosure relates generally to binder powders for use in powder material processing and processes for their preparation. The disclosure further relates to binder powders for use in making solid powder compact forms, solid powder compact forms containing said binder powders and methods for making solid powder compact forms. | 02-20-2014 |
| 20140034510 | CATALYSTS AND METHODS OF USE - The present invention relates to a catalyst comprising (i) a semiconductor preferably comprising one or more metal-(Group VIb) semiconductors, and (ii) a semiconductor material having elevated phosphorous content preferably comprising one or more metal-(Group VIb))-phosphorous species | 02-06-2014 |
| 20130202973 | IONIC LIQUIDS FOR BATTERIES - An organic cation for a battery, including a heteroatom-containing cyclic compound having at least (2) ring structures formed from rings that share at least one common atom, the cyclic compound having both a formal positive charge of at least +1 and a partial negative charge. | 08-08-2013 |
| 20130202577 | DIAGNOSTIC AND PROGNOSTIC ASSAY FOR BREAST CANCER - The invention relates to the finding that T cell protein tyrosine phosphatase (TCPTP) has a tumour suppressor function. In one particular application, the invention provides a method of diagnosis and/or prognosis of cancer in a subject involving the assessment, in a suitable body sample, of any lack or reduction of TCPTP protein and/or Ptpn2 gene expression. The invention also provides a method of treating or preventing cancer in a subject involving administering to a subject an agent for modulating the activity of TCPTP. | 08-08-2013 |
| 20130180912 | MATERIAL AND APPLICATIONS THEREFOR - A gel film or an isolated gel film comprising sheets of graphene or chemically converted graphene at least partially separated by a dispersion medium, such as water, and arranged in a substantially planar manner to form an electrically conductive matrix. | 07-18-2013 |
| 20130137859 | METHODS OF CRYSTALLISING PERFORIN - A method for isolating crystals of perforin including the step of: crystallising perforin from solution at pH 6.4 to 8.0 and 20±5° C. | 05-30-2013 |
| 20130070062 | PARTICAL IMAGE VELOCIMETRY SUITABLE FOR X-RAY PROJECTION IMAGING - A 2D or 3D velocity field is reconstructed from a cross-correlation analysis of image pairs of a sample, without first reconstructing images of the sample spatial structure. The method can be implemented via computer tomographic x-ray particle image velocimetry, using multiple projection angles, with phase contrast images forming dynamic speckle patterns. Estimated cross-correlations may be generated via convolution of a measured autocorrelation function with a velocity probability density function, and the velocity coefficients iteratively optimised to minimise the error between the estimated cross-correlations and the measured cross-correlations. The method may be applied to measure blood flow, and the motion of tissue and organs such as heart and lungs. | 03-21-2013 |
| 20130068294 | DYE-SENSITISED SOLAR CELL WITH NICKEL CATHODE - The present invention relates to a cathode for use in a dye-sensitised solar cell which comprises a redox couple, wherein the cathode comprises: (a) metallic nickel; and (b) intrinsically conducting polymer that, during operation of the cell, reduces an oxidised species of the redox couple. | 03-21-2013 |
| 20120322086 | TESTING DEVICE FOR IDENTIFYING ANTIGENS AND ANTIBODIES IN BIOFLUIDS - A testing device for identifying an antigen or antibody within a biofluid sample including: a substrate having a hydrophilic surface thereon; the surface including a collection zone, and at least one detection zone extending therefrom; wherein the biofluid sample can be mixed with a specific antigen or antibody, and deposited on the collection zone and transferred by capillary action to the detection zone; the antigen or antibody in the biofluid sample reacting with an appropriate said antibody or antigen thereby resulting in a visual indication within the detection zone. | 12-20-2012 |
| 20120316146 | ANAESTHETIC FORMULATION - The present invention relates generally to the field of drug delivery systems for neuroactive steroid anaesthetic agents. More particularly, anaesthetic and sedative formulations are provided in the form of host/guest preparations comprising one or more neuroactive steroid anaesthetics and a cyclodextrin. Particular cyclodextrins contemplated include sulfoalkyl ether cyclodextrins and modified forms thereof. | 12-13-2012 |
| 20120309677 | METHODS FOR REGULATING BLOOD GLUCOSE LEVELS - The invention relates to methods and compositions for reducing blood glucose levels in hyperglycaemic subjects. The methods and compositions may therefore be suitable for treating a disease or condition associated with hyperglycaemia such as, for example, obesity (particularly diet induced obesity (DIO)), weight gain, Type II diabetes mellitus, insulin sensitivity, impaired glucose tolerance and inflammation. In some embodiments, the methods comprise administering a melanocortin-5 receptor (MC5R) agonist to one or more skeletal muscle cells of the subject. Preferred MC5R agonists are those that specifically activate MC5R and/or enhance expression of MC5R, such as the melanocortin analogue, Ac-Nle-c[Asp-Pro-D-Nal(2′)-Arg-Trp-Lys]-NH | 12-06-2012 |
| 20120289897 | NAVIGABLE SYSTEM FOR CATHETER BASED ENDOVASCULAR NEUROSURGERY - A navigable system for catheter based endovascular neurosurgery including: a micro-motor ( | 11-15-2012 |
| 20120238693 | CROSSLINKING METHOD - The invention provides a method of preparing a crosslinked polymer, which method comprises polymerising branched polyunsaturated monomers by a metathesis polymerisation reaction, wherein the branched polyunsaturated monomers contain acyclic ethylenically unsaturated groups that are capable of undergoing polymerization by a metathesis reaction such that the metathesis polymerisation produces a crosslinked polymer and substantially no non-volatile ethylenically unsaturated by-products. | 09-20-2012 |
| 20120237104 | PARTICLE IMAGE VELOCIMETRY SUITABLE FOR X-RAY PROJECTION IMAGING - A 2D or 3D velocity field is reconstructed from a cross-correlation analysis of image pairs of a sample, without first reconstructing images of the sample spatial structure. The method can be implemented via computer tomographic X-ray particle image velocimetry, using multiple projection angles, with phase contrast images forming dynamic speckle patterns. Estimated cross-correlations may be generated via convolution of a measured autocorrelation function with a velocity probability density function, and the velocity coefficients iteratively optimised to minimise the error between the estimated cross-correlations and the measured cross-correlations. The method may be applied to measure blood flow, and the motion of tissue and organs such as heart and lungs. | 09-20-2012 |
| 20120226043 | METHOD FOR THE N-DEMETHYLATION OF N-METHYL HETEROCYCLES - The present invention provides methods of N-demethylating, N-methylated heterocycles and N-methyl, N-oxide heterocycles using a transition metal with an oxidation state of zero, ferrocene or substituted derivatives thereof, or Cr | 09-06-2012 |
| 20120225962 | MOLECULARLY IMPRINTED POLYMERS, METHODS FOR THEIR PRODUCTION AND USES THEREOF - The present invention relates to methods of preparing molecularly imprinted polymers (MIPs) which facilitate chemical hydrolysis and more particularly the hydrolysis of chemical substrates which possess hydrolytically labile bonds such as peptides and proteins. The present invention is thus directed to MIPs designed to possess hydrolytic activity, methods for preparing such MIPs and uses of the MIPs. | 09-06-2012 |
| 20120225811 | INSULIN ANALOGUES - A dicarba analogue of insulin comprising an A-chain and a B-chain or fragments, salts, solvates, derivatives, isomers or tautomers of the A-chain, the B-chain or both, provided that the dicarba analogue is not [A7,B7-(2,7-diaminosuberoyl]-des-(B26-B30)-insulin B25-amide. | 09-06-2012 |
| 20120192952 | THREE-DIMENSIONAL MICROFLUIDIC SYSTEMS - A three-dimensional microfluidic system including: at least one hydrophilic thread along which fluid can be transported through capillary wicking; and at least one hydrophobic substrate for supporting the hydrophilic thread. A method of transporting and mixing a plurality of fluids within a microfluidic system including at least two hydrophilic threads and a hydrophobic substrate having at least two zones, each of the hydrophilic threads supported on a different hydrophobic substrate zone, including: delivering each said fluid to a different hydrophilic thread; and bringing the at least two hydrophilic threads into contact to cause mixing of the fluids. | 08-02-2012 |
| 20120191002 | NEURAL ANALYSIS SYSTEM - A neural analysis system, including: | 07-26-2012 |
| 20120187209 | MICROFLUIDIC APPARATUS FOR THE ATOMISATION OF A LIQUID - An apparatus ( | 07-26-2012 |
| 20120171702 | QUANTITATIVE AND SELF-CALIBRATING CHEMICAL ANALYSIS USING PAPER-BASED MICROFLUIDIC SYSTEMS - A method of determining the concentration of a test fluid sample using a paper-based microfluidic system having a plurality of hydrophilic testing zones, including: a) depositing said test fluid sample on at least one said testing zone; b) depositing a plurality of standard fluid samples or reactives of differing known concentrations on other said testing zones; c) introducing an indicator solution to each said test zone to thereby react with the deposited fluid sample and result in a colour intensity change which is a function of the fluid sample concentration; and d) comparing the differences in colour intensity between the test fluid sample and the standard fluid samples or reactives to thereby determine the concentration of said test fluid sample. | 07-05-2012 |
| 20120161931 | RADIO FREQUENCY TRANSPONDER SYSTEM - A radio frequency transponder is disclosed. In one embodiment, the transponder includes: a substrate and at least one planar antenna on the substrate, the antenna having a shape determining a corresponding resonant frequency of the antenna, wherein the antenna is configured to cause a phase difference between backscattered signals generated in response to excitation of the antenna by orthogonally polarized interrogation signals at the resonant frequency, and the phase difference represents a code of the antenna. | 06-28-2012 |
| 20120142892 | CONTOXIN ANALOGUES AND METHODS FOR SYNTHESIS OF INTRAMOLECULAR DICARBA BRIDGE-CONTAINING PEPTIDES - According to the present invention, there is provided a range of new conotoxin derivatives and methods for synthesizing these analogues and other intramolecular dicarba bridge-containing peptides, including dicarba-disulfide bridge-containing peptides. | 06-07-2012 |
| 20120058500 | PLATELET AGGREGATION USING A MICROFLUIDICS DEVICE - A microfluidics device to provide real time monitoring of platelet aggregation of a biological sample obtained from a subject. The device comprises a channel configured for passage of the biological sample, the channel comprising a protrusion configured to induce an upstream region of shear acceleration coupled to a downstream region of shear deceleration and defining there-between a region of peak rate of shear, the downstream region of shear deceleration defining a zone of platelet aggregation. The device further comprises a platelet detection means for detecting aggregation of platelets in the zone of aggregation as a result of passage of the biological sample through the channel. Methods to assess real time platelet aggregation of a biological sample obtained from a subject are further described. | 03-08-2012 |
| 20120046244 | DUAL FUNCTIONING IONIC LIQUIDS AND SALTS THEREOF - Disclosed herein are ionic liquid compositions comprising active pharmaceutical, biological, and nutritional compounds, and methods of use. Further disclosed are compositions of matter including liquid ion pairs alone or in solution and their use; compositions of ionic liquids that are ‘solvated,’ for example, ‘hydrated’ and their uses. | 02-23-2012 |
| 20120009662 | METHOD OF FABRICATING MICROFLUIDIC SYSTEMS - A method of fabricating a microfluidic system having microfluidic channels on a surface of a hydrophilic substrate, the method including the steps of: hydrophobizing the substrate surface; locating a mask defining the substrate surface, the mask having open areas defining the periphery of the microfluidic channels; and applying an irradiation treatment to areas of the substrate surface exposed by the open areas of the mask, said exposed areas becoming hydrophilic to therefore form said microfluidic channels. | 01-12-2012 |
| 20110303271 | PHOTOVOLTAIC DEVICES - A photovoltaic device including cathode and anode electrodes ( | 12-15-2011 |
| 20110230571 | DIAGNOSTIC AND THERAPEUTIC PROTOCOLS - The present invention relates to methods for determining co-receptor usage of an HIV in a subject including the steps of: culturing a viral preparation derived from the subject's plasma with one or more cell lines which express surface CD4 and CCR5, surface CD4 and CXCR4, or surface CD4, CCR5 and CXCR4, wherein an anticoagulant is added to the viral preparation or to the culture; and screening for infection, wherein the presence or absence of infected cells is indicative of the co-receptors used by the HIV. | 09-22-2011 |
| 20110194120 | METHOD AND DEVICE FOR PHASE MEASUREMENT - The present invention relates to the field of phase measurement, particularly optical phase measurement. In one form, the invention relates to a method and device for measuring the phase between distinct signals by converting phase variations between the signals into amplitude variations. In one embodiment the invention provides a method of arranging the structure of a two-dimensional or three-dimensional crystal to measure the phase between signals, comprising the steps of (i) providing a respective waveguide for each signal and (ii) providing a micro-cavity array arranged to provide a resonance output in response to the phase of the signals. The invention has application to a wide range of apparatus and devices across many industries including communications, food technology, pharmacology, medicine and biology. | 08-11-2011 |
| 20110190270 | METHODS OF TREATING THROMBOEMBOLIC DISORDERS - The field of the invention relates to methods for dissolving a thrombus using inhibitors of platelet contractility. More particularly, the present invention relates to the use of an inhibitor of platelet contractility in combination with one or more thrombolytic agents and optionally one or more anticoagulants for inhibiting platelet contraction and consolidation in the developing thrombus. | 08-04-2011 |
| 20110148253 | PIEZOELECTRIC ACTUATOR FOR USE IN MICRO ENGINEERING APPLICATIONS - A piezoelectric actuator including a piezoelectric element and an elongate transducer mounted on the piezoelectric element. The transducer is formed from an elongate cylindrical member, and at least one helical slot is provided around the outer surface of the cylindrical member to enable coupling of resonance modes of the transducer when actuated by the piezoelectric element. | 06-23-2011 |
| 20110142790 | Polyol Based - Bioceramic Composites - Polyol-bioceramic composites are prepared by the reaction of a polyol and polycarboxylic acid in the presence of a bioceramic. Implantable medical devices fabricated at least in part with the crosslinked polyol-bioceramic composite materials are useful in a wide variety of applications. | 06-16-2011 |
| 20110117454 | ELECTRODE FOR ELECTROCHEMICAL CELLS - The invention relates to an electrode for oxygen reduction comprising a porous organic material and at least one inherently conducting polymer such as a charge transfer complex or a conductive polymer, optionally combined with a non-conducting polymer. A current conductor may be located intermediate the porous organic material and the inherently conductive polymer. The electrode is suitable for use with an ion-conducting membrane and fuel such as hydrogen, an alcohol or borohydride to form a fuel-cell. The electrode is also suitable for use with an anode, such as a reactive metal and an electrolyte to form a battery. | 05-19-2011 |
| 20110110933 | ECTOPIC PREGNANCY TREATMENT - The invention pertains to methods for treating ectopic pregnancy. More particularly, the present invention relates to methods for treating unruptured ectopic pregnancy using a non-surgical method comprising the administration of an EGFR inhibitor alone or in combination with an anti-metabolite e.g. methotrexate (MTX). The methodology is potentially applicable to treatment of unruptured ectopic pregnancies of all sizes. | 05-12-2011 |
| 20110086911 | NOVEL BISMUTH(III) NSAID COMPOUNDS AND METHODS FOR THEIR USE - The present invention relates to the field of non-specific anti inflammatory drugs (NSAIDs). In particular, the invention relates to bismuth(III) tris-carboxylate complexes having the formula [Bi(III)L | 04-14-2011 |
| 20110042225 | ELECTROCHEMICAL NANOCOMPOSITE BIOSENSOR SYSTEM - The present invention relates to an electrode useful in electrochemical nanobiosensors for determining the presence or concentration of analytes in aqueous samples. In particular, the electrode comprises a biocatalyst or other bioreceptor entrapped in a conducting polymeric film deposited on a conducting material and a non-conducting or conducting coating. In particular embodiments, the conducting polymeric layer also comprises metallic nanoparticles. Electrochemical nanobiosensors containing the electrode, methods of making the electrode or sensor and methods of detecting analytes are other aspects of the invention. | 02-24-2011 |
| 20110039915 | IMMUNOSTIMULATORY siRNA MOLECULES - The present invention relates to a double-stranded siRNA molecule that is capable of silencing gene expression as well as inducing an immune response. The molecule comprises a sense strand and an antisense strand, wherein the antisense strand comprises a first nucleotide sequence that is specifically complementary to mRNA transcribed from a target gene, and the sense strand comprises a second nucleotide sequence that is substantially or perfectly complementary to the antisense strand with the exception that the second nucleotide sequence comprises at least one immunostimulatory motif comprising two or more non-complementary nucleotides. Such a molecule may be utilized in a method of treating or preventing a disease or condition (such as a viral infection, a bacterial infection, or cancer) in a subject. | 02-17-2011 |
| 20100331521 | Controlled Polymerisation Process - The present invention relates to a controlled metathesis-driven polymerisation process which is particularly useful for the synthesis of biological polymers such as peptides and polymers. The invention also provides metathesisable supports, groups and linkers for use in the process. | 12-30-2010 |
| 20100276955 | TREATMENT OF RAILWAY WHEELS - A method of treating a steel railway wheels to form a required distribution of compressive residual stress in the rim. In general terms the wheel heated and then quenched from the plate towards the rim. The wheel is first heated to form austenite throughout the plate and rim portions. The wheel is then cooled to form bainite/martensite in the plate portion. The wheel is cooled to form bainite/martensite in an inner portion of the rim. The wheel is cooled to form bainite/martensite in an outer portion of the rim. | 11-04-2010 |
| 20100274554 | SPEECH ANALYSIS SYSTEM - A speech analysis system, including a kurtosis module for processing a coded sound signal to generate kurtosis measure data; a wavelet module for processing the coded sound signal to generate wavelet coefficients; and a classification module for processing the wavelet coefficients and the kurtosis measure data to generate label data representing a classification for the coded sound signal. The sound signal is classified as environmental noise, silence, speech from a single speaker, speech from multiple speakers, speech from a single speaker plus environmental noise, or speech from multiple speakers plus environmental noise. Speech is further classified as voiced or unvoiced. | 10-28-2010 |
| 20100266552 | TREATMENT OF CHRONIC LUNG DISEASE - A method of cellular therapy for a lung disease or condition in a subject is disclosed, wherein the method involves the administration of multipotent epithelial stem cells derived from amnion tissue (AECs). In a particular application, the method is used for the treatment of lung diseases and conditions such as chronic lung diseases including chronic obstructive pulmonary disease (COPD), acute lung conditions such as acute respiratory distress syndrome (ARDS), and ventilator associated lung injury (VALI). | 10-21-2010 |
| 20100261978 | NEURAL RESPONSE SYSTEM - A neural response system, including a plurality of filters for each receiving and filtering a plurality of tilt response signals obtained from a person; a segmenter for segmenting the filtered response signals into time segments; and a neural event extractor for performing a neural event extraction process on each of the time segments to obtain and generate biomarker data representing a plurality of biomarkers for each segment. | 10-14-2010 |
| 20100221746 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASE - The present invention relates to pharmaceutical compositions for the treatment and/or prophylaxis of disease associated with fibrosis in a vertebrate, said composition comprising at least one activin antagonist, and optionally a pharmaceutically acceptable carrier, adjuvant and/or diluent. The invention also relates to methods of treatment of disease associated with fibrosis in a vertebrate, as well as methods for diagnosing such conditions, and kits therefor. | 09-02-2010 |
| 20100201228 | METHOD OF COATING - The present invention provides a method of depositing a metallic layer on to a surface of a piezoelectric substrate, which method comprises the application of cold spraying to deposit the metallic layer or layers. | 08-12-2010 |
| 20100191665 | SERVICE VALUE CALCULATION METHOD, SYSTEM, AND PROGRAM - A service value calculation system includes: crisis problem inspection means which detects a crisis or a problem of a service object; and virtual damage amount calculation means which calculates a virtual damage amount generated if a detected crisis or problem is not solved when a service is not applied and calculates the service value. | 07-29-2010 |
| 20100068214 | Identification of Candidate Vaccine Antigens from Dichelobacter Nodosus - This invention relates to a prophylactic and/or therapeutic treatment of footrot, and in particular to a vaccine effective in prophylactic and/or therapeutic treatment of footrot. Specific polypeptides of | 03-18-2010 |
| 20100063788 | METHOD OF MODELLING THE INTERACTION BETWEEN DEFORMABLE OBJECTS - The present invention provides methods for determining a collision between a first deformable object and a second deformable object in a virtual reality simulation, the method including the steps of providing a first test capable of determining the proximity of the first object to the second object, providing a second test capable of determining the proximity of the first object to the second object, wherein the second test is more comprehensive than the first test, and wherein the second test is capable of being implemented once the first test returns a positive result. Since the more comprehensive test is implemented only when a collision is likely or imminent (as determined by the first test), the processor executing the simulation is not unduly burdened, and can devote resources to other tasks required by the simulation program. | 03-11-2010 |
| 20100036089 | Methods for the Synthesis of Dicarba Bridges in Organic Compounds - The present invention relates to methods for forming dicarba bridges in organic compounds. This involves the use of a pair of complementary metathesisable groups on the organic compound, and subjecting the compound to cross-metathesis under microwave radiation conditions. In an alternative, the compounds contain a turn-inducing group between the pair of cross-metathesisable groups to facilitate the cross-metathesis. | 02-11-2010 |
| 20100022749 | Contoxin Analogues and Methods for Synthesizing Same - According to the present invention, there is provided a range of new conotoxin derivatives and methods for synthesizing these analogues and other intramolecular dicarba bridge-containing peptides, including dicarba-disulfide bridge-containing peptides. | 01-28-2010 |
| 20090220239 | METHODS AND APPARATUS FOR OPTICAL TRANSMISSION OF DIGITAL SIGNALS - A method of communicating digital information over a dispersive optical channel includes encoding the digital information into a plurality of data blocks, each of which includes a number of bits of the information. A time-varying electrical signal is generated which corresponds with each of said data blocks. The time-varying electrical signal is applied to an optical transmitter ( | 09-03-2009 |
| 20090206171 | CONCENTRATION AND DISPERSION OF SMALL PARTICLES IN SMALL FLUID VOLUMES USING ACOUSTIC ENERGY - A method of manipulating particles suspended within a fluid droplet using a microfluidic system including a piezo-electric substrate ( | 08-20-2009 |
| 20090169213 | METHODS AND APPARATUS FOR OPTICAL TRANSMISSION OF DIGITAL SIGNALS | 07-02-2009 |
| 20090076742 | ESTIMATION OF WHEEL RAIL INTERACTION FORCES - A method of estimating contact forces between the wheels of a railway wagon and a rail track, for use in determining information such as the likelihood of derailment. Accelerations of the body of the wagon are measured using motion sensors located at suitable points on the body. Forces on the side frames of the wagon are calculated based on the accelerations of the body and predetermined parameters of the body. Forces on the wheels of the wagon are calculated based on the accelerations of the body and predetermined parameters of the body. The contact forces between the wheels and the rails are then calculated based on the forces calculated for the side frames and the wheels. The calculations are carried out using an inverse model of the wagon system. Equipment which implements the method is also described. | 03-19-2009 |
| 20080317763 | Regulation of Metalloprotease Cleavage of Cell Surface Proteins - Elucidation of the crystal structure of an ADAM10 substrate-recognition and proteinase-positioning module comprising the protein cysteine-rich and disintegrin domains, and detailed functional analysis revealed that an acidic pocket within the cysteine-rich domain forms a substrate-recognition site. The binding of this pocket to receptor/ligand complexes facilitates effective ligand cleavage, which is prevented when critical residues within the pocket are changed. This provides use of the surface pocket within the extracellular domain of ADAM10, and the corresponding structure in related proteases such as ADAM17, as a target for structure-based computational and high-throughput screens for small-molecule substrate-specific inhibitors or monoclonal antibodies that inhibit ADAM protease cleavage of ephrins and other ADAM10 or ADAM17 substrates. These inhibitors will be useful in therapeutic intervention of tumour development, invasion and metastasis and other diseases which involve the activity of the ADAM10 and ADAM17 proteases, such as inflammation, cardio-vascular disease, arthritis and other auto-immune diseases. | 12-25-2008 |
| 20080293917 | Peptide Purification By Means Of Metal Ion Affinity Chromatography - A polymer substrate functionalized with a functionality comprising at least one cyclic, metal ion coordinating ligand group, the cyclic ligand group comprising at least 3 metal ion coordinating donor atoms independently selected from the group consisting of N, O and S. | 11-27-2008 |
| 20080286272 | EphA3 Antibodies for the Treatment of Solid Tumors - The invention provides methods and compositions comprising anti-EphA3 antibodies for the treatment of solid tumors. | 11-20-2008 |
| 20080279812 | Disease Prevention and Vaccination Prior to Thymic Reactivation - The present disclosure provides methods for preventing or treating illness, improving responsiveness to immunization, and improving the efficacy of gene therapy in a patient by disrupting sex steroid signalling in the patient, wherein the bone marrow and other immune cell functionality is improved without, prior to, or concurrently with, thymic regeneration. In some embodiments, sex steroid signalling is interrupted or ablated in the patient by the administration of LHRH agonists, LHRH antagonists, anti-LHRH receptor antibodies, anti-LHRH vaccines, anti-androgens, anti-estrogens, selective estrogen receptor modulators (SERMs), selective androgen receptor modulators (SARMs), selective progesterone response modulators (SPRMs), ERDs, aromatase inhibitors, or various combinations thereof. | 11-13-2008 |
| 20080199495 | Stimulation of thymus for vaccination development - The present disclosure provides methods for enhancing the response of a patient's immune system to vaccination. This is accomplished by reactivating the thymus. Optionally, hematopoietic stem cells, autologous, syngeneic, allogeneic or xenogeneic, are delivered to increase the speed of regeneration of the patient's immune system. In one embodiment the hematopoietic stem cells are CD34 | 08-21-2008 |
