Lanzatech New Zealand Limited Patent applications |
Patent application number | Title | Published |
20160040193 | GENETICALLY ENGINEERED BACTERIUM WITH ALTERED CARBON MONOXIDE DEHYDROGENASE (CODH) ACTIVITY - The invention provides genetically engineered microorganisms with altered carbon monoxide dehydrogenase (CODH) activity and methods related thereto. In particular, the invention provides a genetically engineered carboxydotrophic acetogenic bacterium having decreased or eliminated activity of CODH1 and/or CODH2. In certain embodiments, the bacterium may also have increased activity of CODH/ACS. The invention further provides a method for producing a product by culturing the bacterium in the presence of a gaseous substrate comprising one or more of carbon monoxide, carbon dioxide, and hydrogen. | 02-11-2016 |
20150337343 | A FERMENTATION PROCESS - This invention relates generally to method for producing products, particularly alcohols, by microbial fermentation. In particular, the invention relates to methods for increasing the efficiency of the fermentation, by providing a method for treating the used fermentation broth to produce a treated permeate which is then passed back to the bioreactor. The invention provides a method whereby at least one treatment step used to treat the permeated, produces a gaseous product which is then used in one or more stages of the fermentation process. | 11-26-2015 |
20150337341 | FERMENTATION PROCESS FOR THE PRODUCTION AND CONTROL OF PYRUVATE-DERIVED PRODUCTS - A process for producing and controlling pyruvate derived products during the fermentation of a CO containing substrate by an acetogenic carboxydotrophic microorganism has been developed. The process involves increasing the concentration of at least one nutrient selected from the group consisting of vitamin B1, vitamin B5, vitamin B7 and mixtures thereof above the cellular requirement of the microorganism. When the concentration is increased, the production of 2,3-butanediol (2,3-BDO) increases whereas the production of the other metabolites is virtually unchanged. The effect is reversible so that when the concentration is decreased, the production of 2,3-BDO is also decreased. This allows one to control the ratio of ethanol:2,3-BDO to a desired value which can vary from about 4:1 to about 1:2. | 11-26-2015 |
20150247171 | Carbon Capture in Fermentation - The present invention provides methods and systems for improving carbon capture from a gas stream comprising methane. Further, the invention provides a method for the production of at least one alcohol, and at least one acid from a gas stream comprising methane, the method comprising reforming a gas stream comprising methane to provide a syngas, in a first bioreactor fermenting the syngas to produce at least one acid and a tail gas comprising CO | 09-03-2015 |
20140370559 | FERMENTATION OF WASTE GASES - The invention relates to the microbial fermentation of gaseous substrates to produce one or more products. The invention relates to the microbial fermentation of a gaseous substrate derived from the conversion of a biogas stream. The invention relates to the conversion of a biogas stream comprising methane to a gaseous substrate comprising CO or CO plus H2, and the production of one or more products from the microbial fermentation of said gaseous substrate. | 12-18-2014 |
20140273115 | SYSTEM AND METHOD FOR CONTROLLING METABOLITE PRODUCTION IN A MICROBIAL FERMENTATION - A method is provided for controlling a metabolic profile of an anaerobic microbial fermentation culture. In particular, a metabolic profile of a fermentation process is controlled by controlling the amount of dissolved CO2 provided to a culture. Further provided is a method of producing one or more products by microbial fermentation of a gaseous substrate through feeding tail gas CO2 from a reactor to a second reactor, or by recycling tail gas CO2 to the same reactor. | 09-18-2014 |
20140212976 | Recombinant microorganisms comprising NADPH dependent enzymes and methods of production therefor - The invention provides a recombinant carboxydotrophic Clostridia microorganism with increased overall utilization of NADPH relative to a parent microorganism. Further, the invention provides a method of producing a recombinant carboxydotrophic Clostridia microorganism which exhibits increased NADPH utilization relative to a parental microorganism. In particular, the invention relates to increasing the overall utilization of NADPH in a recombinant carboxydotrophic Clostridia microorganism in order to increase the production of at least one fermentation product by the microorganism. | 07-31-2014 |
20140212937 | System and Method for Improved Gas dissolution - The invention provides a microbubble generation system with increased efficiency and flexibility compared to known systems. Further, the invention provides a method of microbubble generation. In particular, invention relates to increasing the efficiency of a fermentation reaction by reducing bubble size and increasing gas absorption into a liquid fermentation broth. | 07-31-2014 |
20140186928 | Recombinant Microorganism and Methods of Production Thereof - The invention relates, inter alia, to novel genetically modified microorganisms capable of using CO to produce 1-butanol and/or a precursor thereof, novel methyltransferases and nucleic acids encoding same, methods for producing genetically modified microorganisms using said novel methyltransferases, and methods of producing 1-butanol and/or a precursor thereof by microbial fermentation. | 07-03-2014 |
20140154755 | FERMENTATION PROCESS - The invention provides methods and systems for the production of lipid products from a gaseous substrate using a two stage fermentation process. The method comprises providing a gaseous substrate comprising CO or CO | 06-05-2014 |
20140141477 | FERMENTATION PROCESS - The invention provides methods and systems for the production of lipid products from a gaseous substrate using a two stage fermentation process. The method comprises providing a gaseous substrate comprising CO, CO | 05-22-2014 |
20140065698 | Recombinant microorganisms and uses therefor - A stereospecific enzyme in | 03-06-2014 |
20130330809 | Recombinant microorganisms and uses therefor - Carboxydotrophic acetogenic microorganisms do not produce MEK and/or 2-butanol. They lack the biosynthesis pathways to make these products. In addition, they produce the intermediate (R,R)-2,3-butanediol whereas the production of MEK and 2-butanol requires production of the intermediate (R,S)-2,3-butanediol. Nonetheless, the production of MEK and/or 2-butanol can be accomplished using recombinant microorganisms adapted to express or overexpress key enzymes in the MEK and/or 2-butanol biosynthesis pathways. Such microorganisms, such as the carboxydotrophic acetogen | 12-12-2013 |
20130323820 | Recombinant microorganisms and uses therefor - Terpenes are valuable commercial products used in a diverse number of industries. Terpenes may be produced from petrochemical sources and from terpene feed-stocks, such as turpentine. However, these production methods are expensive, unsustainable and often cause environmental problems including contributing to climate change. Microbial fermentation provides an alternative option for the production of terpenes. One or more terpenes and/or precursors can be produced by microbial fermentation of a substrate comprising CO. Recombinant microorganisms may be used in such methods. Carboxydotrophic, acetogenic, recombinant microorganisms can be used in such methods. The recombinant microorgnsims may contain exogenous mevalonate (MVA) pathway enzymes and/or DXS pathway enzymes, for example. | 12-05-2013 |
20130323806 | Recombinant microorganisms and uses therefor - Bacteria are genetically engineered to produce 3-hydroxypropionate (3-HP). The bacteria are carboxydotrophic acetogens. The bacteria produce acetyl-coA using the Wood-Ljungdahl pathway for fixing CO/CO | 12-05-2013 |
20130316424 | Carbon capture in fermentation - The invention relates to methods of capturing carbon by microbial fermentation of a gaseous substrate comprising CO. The methods of the invention include converting CO to one or more products including alcohols and/or acids and optionally capturing CO2 to improve overall carbon capture. In certain aspects, the invention relates to processes for producing alcohols, particularly ethanol, from industrial waste streams, particularly steel mill off-gas. | 11-28-2013 |
20130316412 | FERMENTATION AND SIMULATED MOVING BED PROCESS - The invention provides an improved method for the production, separation and recovery of one or more fermentation products from a fermentation broth. Further, the invention provides a method for increasing efficiency of a fermentation reaction. In particular, the invention relates to a fermentation system which incorporates a simulated moving bed for separation of fermentation products from a fermentation broth, and a corresponding method | 11-28-2013 |
20130316364 | Selection Method and Recombinant Microorganisms and uses Therefor - One or more genes in a biosynthesis pathway for a vitamin or other essential nutrient which is needed for the survival of a microorganism can be used as an effective selective marker to identify cells transformed with an exogenous nucleic acid. The microorganism does not naturally contain or express the one or more gene. This permits genetic manipulations to be performed. It permits lower cost fermentations to be performed. It permits production of the essential nutrient for subsequent commodity use. | 11-28-2013 |
20130267006 | Enzyme-Altered Metabolite Activity - The present invention relates to mutant alcohol dehydrogenase enzymes, microorganisms comprising same, and methods for the production of one or more products by microbial fermentation using said microorganisms. | 10-10-2013 |
20130260429 | Fermentation Process - This invention relates generally to methods for increasing the efficiency of microbial growth and production of products, such as alcohols and acids by microbial fermentation of substrates containing carbon monoxide. More particularly the invention relates to the provision of an alternative sulphur source to a liquid nutrient medium, such that sulphur is available to one or more microorganisms of the fermentation. | 10-03-2013 |
20130252230 | Alcohol Production Process - The invention relates to a process for optimising the production of ethanol by microbial fermentation, particularly microbial fermentation of substrates comprising CO. The process involves monitoring the hydrogen production by the microorganism, determining an optimum hydrogen production and adjusting the substrate supply rate in response to a change in the hydrogen production thereby keeping the hydrogen production within a desired range. | 09-26-2013 |
20130230894 | Optimised Fermentation Media - The invention relates to improvements in the production of alcohols by microbial fermentation, particularly to production of alcohols by microbial fermentation of a substrate comprising CO. It more particularly relates to the addition of an inorganic sulfur source to a fermentation system such that one or more micro-organisms convert a substrate comprising CO to alcohols. In a particular embodiment, a microbial culture is provided with sodium polysulfide, wherein a substrate comprising CO is converted to products including ethanol and 2,3-butanediol. | 09-05-2013 |
20130217096 | NOVEL BACTERIA AND METHODS OF USE THEREOF - This invention relates generally to the field of microbial fermentation of gases. It more particularly relates to a novel strain of | 08-22-2013 |
20130210096 | Methods and Systems for the Production of Hydrocarbon Products - Methods and systems for the production of hydrocarbon products, including providing a substrate comprising CO to a bioreactor containing a culture of one or more micro-organisms; and fermenting the culture in the bioreactor to produce one or more hydrocarbon products. The substrate comprising CO is derived from an industrial process selected from the group comprising steam reforming processes, refinery processes, steam cracking processes, and reverse water gas shift processes. | 08-15-2013 |
20130177955 | PROCESS FOR PRODUCTION OF ALCOHOLS BY MICROBIAL FERMENTATION - The invention provides method for producing butanediol and specifically 2,3-butanediol by anaerobic fermentation of a gaseous substrate comprising CO by a culture of at least one micro-organism. In accordance with particular methods of the invention, 2,3-butanediol is produced by anaerobic fermentation of substrates including carbohydrates and carbon monoxide. The invention further provides for the up-regulation of a native 2,3-butanediol dehydrogenase gene in the at least one micro-organism. The 2,3-butanediol can be further converted to compounds such as butene(s), butadiene and methyl ethyl ketone. These compounds can be further converted to chemical products such as 2-butanol. | 07-11-2013 |
20130157322 | PROCESS FOR PRODUCING ETHANOL AND ETHYLENE VIA FERMENTATION - A process for converting a substrate such as carbon monoxide to useful chemicals has been developed. The process involves providing a substrate comprising CO to a bioreactor which contains a culture of one or more micro-organisms and anaerobically fermenting the substrate to produce ethanol. The ethanol is next converted to one or more chemical products via the compound ethylene. The source of the CO can be an industrial process such as the ferrous metal products manufacturing. The microorganism can be | 06-20-2013 |
20130109066 | Acid Production by Fermentation | 05-02-2013 |
20130084559 | Methods of Sustaining Culture Viability - The present invention relates to methods for sustaining a microbial culture during periods of limited substrate supply. In accordance with the methods of the invention, a microbial culture comprising carboxydotrophic bacteria can be sustained during periods of limited substrate supply by maintaining the temperature of the microbial culture at a temperature below an optimum operating temperature. Examples of periods of limited substrate supply include when the microbial culture is transported to a remote location or during time when it is stored. | 04-04-2013 |
20130065282 | Fermentation Process - Methods and systems for the production of one or more lipid products from a gaseous substrate using a two stage fermentation process are provided. The method comprises providing a gaseous substrate comprising CO | 03-14-2013 |
20130059352 | Alcohol Production Process - The invention relates generally to methods for improving the microbial fermentation of gaseous substrates to produce one or more products. The invention relates to the capture of one or more components of a gaseous stream in a liquid. The invention relates to the deoxygenation of a liquid by contacting the liquid with a gaseous stream. The invention relates to methods of increasing efficiency of fermentation by using gas streams exiting a bioreactor to deoxygenate liquid streams entering a bioreactor. | 03-07-2013 |
20130045517 | FERMENTATION OF WASTE GASES - The invention relates to the microbial fermentation of gaseous substrates to produce one or more products. The invention relates to the microbial fermentation of a gaseous substrate derived from the conversion of a biogas stream. The invention relates to the conversion of a biogas stream comprising methane to a gaseous substrate comprising CO and/or H2, and the production of one or more products from the microbial fermentation of said gaseous substrate. | 02-21-2013 |
20120309075 | Novel Bacteria and Methods of Use thereof - A biologically pure isolate of a selected bacterium derived from | 12-06-2012 |
20120309066 | Carbon Capture in Fermentation - The invention relates to processes for converting CO by microbial fermentation to one or more products including alcohols and/or acids and optionally capturing CO | 12-06-2012 |
20120301934 | Process for the Production of Esters - Methods for producing an ester from a gas comprising carbon monoxide. More specifically the invention provides for methods for producing one or more products by the anaerobic fermentation of a gaseous substrate comprising CO and the subsequent conversion of the one or more products to an ester in a down-stream reaction. The invention further provides methods for improving the efficiency of the production of esters from gaseous substrates. | 11-29-2012 |
20120252083 | FERMENTATION PROCESS FOR PRODUCING ISOPROPANOL USING A RECOMBINANT MICROORGANISM - The invention provides, inter alia, methods for the production of acetone, isopropanol and/or precursors of acetone and/or isopropanol by microbial fermentation of substrates comprising CO, genetically modified microorganisms of use in such methods, nucleic acids suitable for preparation of genetically modified microorganisms, a novel alcohol dehydrogenase and nucleic acids encoding same. | 10-04-2012 |
20120252082 | Fermentation Process For Controlling Butanediol Production - Methods for improving the efficiency of 2,3-butanediol fermentations are disclosed. More specifically methods of increasing the butanediol productivity from the anaerobic fermentation of a substrate comprising carbon monoxide or carbon monoxide and hydrogen by one or more caboxydotrophic acetogenic bacteria are disclosed. The method includes supplying a hydrogen depleted substrate to increase butanediol productivity. The method includes producing butanediol at a volumetric productivity rate of at least 15 g/L/day. | 10-04-2012 |
20120156739 | FERMENTATION METHOD - This invention relates to the integration of an ammonia production process with a fermentation process to produce products such as alcohols and/or acids in addition to ammonia. In a specific embodiment, a natural gas stream comprising methane is passed to a reforming zone to produce a substrate comprising CO and H | 06-21-2012 |
20120045807 | PROCESS FOR PRODUCING CHEMICALS USING MICROBIAL FERMENTATION OF SUBSTRATES COMPRISING CARBON MONOXIDE - A process for converting a substrate such as carbon monoxide to useful chemicals has been developed. The process involves providing a substrate comprising CO to a bioreactor which contains a culture of one or more micro-organisms and anaerobically fermenting the substrate to produce 2,3-butanediol (BDO). The BDO is next converted to one or more of butane, butadiene and/or methyl ethyl ketone which in turn can be converted to other compounds. The source of the CO can be an industrial process such as the ferrous metal products manufacturing. The microorganism can be | 02-23-2012 |
20110300593 | OPTIMISED FERMENTATION MEDIA - The invention relates to improvements in the production of alcohols by microbial fermentation, particularly to production of alcohols by microbial fermentation of a substrate comprising CO. It more particularly relates to the provision of an inorganic organic sulfur source to a fermentation system such that one or more micro-organisms convert a substrate comprising CO to alcohols. In a particular embodiment, a microbial culture is provided with sodium polysulfide, wherein a substrate comprising CO is converted to products including ethanol and 2,3-butanediol. | 12-08-2011 |
20110281336 | METHODS OF SUSTAINING CULTURE VIABILITY - The present invention relates to methods for sustaining a microbial culture during periods of limited substrate supply. In accordance with the methods of the invention a microbial culture comprising carboxydotrophic bacteria can be sustained during periods of limited substrate supply by maintaining the temperature of the microbial culture at a temperature below an optimum operating temperature. | 11-17-2011 |
20110256600 | Recombinant Microorganisms and Methods of Use Thereof - The invention provides a recombinant microorganism capable of producing one or more products by fermentation of a substrate comprising CO, wherein the microorganisms has an increased tolerance to ethanol. The invention also provides, inter alia, methods for the production of ethanol and one or more other products from a substrate comprising CO. | 10-20-2011 |
20110236941 | RECOMBINANT MICROORGANISM AND METHODS OF PRODUCTION THEREOF - A novel genetically modified microorganisms capable of using CO to produce 1-butanol and/or a precursor thereof, novel methyltransferases and nucleic acids encoding same, methods for producing genetically modified microorganisms using said novel methyltransferases, and methods of producing 1-butanol and/or a precursor thereof by microbial fermentation. | 09-29-2011 |
20100323417 | CARBON CAPTURE IN FERMENTATION - The invention relates to methods of capturing carbon by microbial fermentation of a gaseous substrate comprising CO. The methods of the invention include converting CO to one or more products including alcohols and/or acids and optionally capturing CO2 to improve overall carbon capture. In certain aspects, the invention relates to processes for producing alcohols, particularly ethanol, from industrial waste streams, particularly steel mill off-gas. | 12-23-2010 |
20100317074 | CARBON CAPTURE IN FERMENTATION - The invention relates to methods of capturing carbon by microbial fermentation of a gaseous substrate comprising CO. The methods of the invention include converting CO to one or more products including alcohols and/or acids and optionally capturing CO2 to improve overall carbon capture. In certain aspects, the invention relates to processes for producing alcohols, particularly ethanol, from industrial waste streams, particularly steel mill off-gas. | 12-16-2010 |
20090275787 | Alcohol Production Process - The invention relates to methods for the production of alcohols by microbial fermentation, particularly microbial fermentation of substrates comprising glycerol and/or acetate, to butanol. | 11-05-2009 |