JAPAN TOBACCO INC. Patent applications |
Patent application number | Title | Published |
20160107365 | ROD MEMBER EXTRUSION-MOLDING SYSTEM AND EXTRUSION-MOLDING METHOD THEREFOR - A system for executing a rod member extrusion-molding method of the present invention has an extrusion-molding machine of a rod member, a transfer conveyor, a delivery line of the rod member between the extrusion-molding machine and the transfer conveyor, a measurement position defined on the delivery line and dividing the delivery line into an upstream section and a downstream section, a measurement device measuring an outer diameter of the rod member in the measurement position, a first roller conveyor forming a part of the section at least directly upstream of the measurement position, a second roller conveyor forming the downstream section, and a control device performing feedback control of a transfer speed of the transfer conveyor based on the outer diameter obtained in the measurement device. | 04-21-2016 |
20160100626 | TOBACCO RAW MATERIAL, METHOD FOR MANUFACTURING SAME, AND TOBACCO PRODUCT - The present invention provides a tobacco raw material having a good smoking flavor and a method for producing the same. Provided is a tobacco raw material having a ratio, which is expressed as “water-extracted material weight/hexane-extracted material weight,” between the weight of an extracted material obtained by extraction using n-hexane as a solvent and the weight of an extracted material obtained following the extraction by further extraction using water as a solvent, of 0 or more and 1.5 or less. | 04-14-2016 |
20160083737 | AGROBACTERIUM BACTERIUM TO BE USED IN PLANT TRANSFORMATION METHOD - This invention relates to the | 03-24-2016 |
20160073678 | MANUFACTURING METHOD OF COMPOSITION ELEMENT OF FAVORITE ITEM INCLUDING FLAVOR COMPONENT, AND COMPOSITION ELEMENT OF FAVORITE ITEM, INCLUDING FLAVOR COMPONENT - The production process comprises a step (A) in which an alkali-treated tobacco source is heated to make the tobacco source release a flavoring ingredient into a gas phase, a step (B) in which the flavoring ingredient released into the gas phase is brought into contact with a given solvent which is a liquid substance at ordinary temperature, thereby trapping the flavoring ingredient in the given solvent, and a step (C) in which the given solvent is added to a constituent element. | 03-17-2016 |
20160032309 | NUCLEIC ACID IMPARTING HIGH-YIELDING PROPERTY TO PLANT, METHOD FOR PRODUCING TRANSGENIC PLANT WITH INCREASED YIELD, AND METHOD FOR INCREASING PLANT YIELD - An object of the present invention is to provide nucleic acids capable of imparting high-yielding ability to plants. Another object of the present invention is to use such nucleic acids to produce transgenic plants at increased yield, as well as to provide methods for increasing the yield of plants. By introducing into a plant a construct in which a promoter of a pseudo-response regulator gene in | 02-04-2016 |
20150374041 | BURNING TYPE HEAT SOURCE AND FLAVOR INHALER - A burning type heat source ( | 12-31-2015 |
20150374038 | PACKAGE - A package houses a heat source having a columnar shape extending along a predetermined direction and houses a tubular member having a tubular shape. The package includes a bottom surface and a heat source holder holding the heat source so that the predetermined direction is directed toward a direction crossing the bottom surface. | 12-31-2015 |
20150374037 | BURNING TYPE HEAT SOURCE, FLAVOR INHALER, AND MANUFACTURING METHOD OF BURNING TYPE HEAT SOURCE - A burning type heat source ( | 12-31-2015 |
20150374036 | NON-BURNING TYPE FLAVOR INHALER - The non-combustion-type flavor inhaler ( | 12-31-2015 |
20150335062 | FLAVOR SOURCE FOR NON-BURNING INHALATION TYPE TOBACCO PRODUCT, AND NON-BURNING INHALATION TYPE TOBACCO PRODUCT - A flavor source ( | 11-26-2015 |
20150292152 | METHOD FOR PREPARING BLACK LIQUOR AND METHOD FOR PREPARING FLAVOR COMPONENT-CONTAINING LIQUID - A method for preparing a black liquor according to the present invention comprises digesting a tobacco raw material under an alkaline condition to obtain the black liquor. Further, a method for preparing a flavor component-containing liquid according to the present invention comprises digesting a tobacco raw material under an alkaline condition, separating the obtained digesting product into a black liquor and a tobacco fiber, and desalinating the black liquor to obtain the flavor component-containing liquid. | 10-15-2015 |
20150291671 | MODIFIED BIOTIN-BINDING PROTEIN - The present invention provides a modified biotin-binding protein comprising an amino acid sequence represented by SEQ ID NO: 2 or its modified sequence and having a biotin-binding activity and replacement selected from the group consisting of:
| 10-15-2015 |
20150237913 | NON-BURNING TYPE FLAVOR INHALER - A non-combustion-type flavor inhaler is provided with: a heat source which has a plate-like shape having a pair of main surfaces; a flavor generation source having a plate-like shape having a pair of main surfaces; and a holder for receiving both the heat source and the flavor generation source. The heat source and the flavor generation source are stacked on each other within the holder in such a manner that one of the main surfaces of the heat source and one of the main surfaces of the flavor generation source face each other. The flavor generation source has: an introduction region for introducing air into the flavor generation source; and a delivery region for delivering air from the inside of the flavor generation source. The introduction region and the delivery region are provided on the surfaces of the flavor generation source, which are other than the main surface which faces the heat source. | 08-27-2015 |
20150174117 | 4-OXOQUINOLINE COMPOUND AND USE THEREOF AS PHARMACEUTICAL AGENT - An anti-HIV agent containing, as an active ingredient, a 4-oxoquinoline compound represented by the following formula [I] | 06-25-2015 |
20150136161 | BASIS WEIGHT MEASURING APPARATUS AND METHOD FOR SHEET TOBACCO, AND MANUFACTURING SYSTEM AND METHOD FOR SHEET TOBACCO - A measuring apparatus for performing a basis weight measuring method for sheet tobacco according to the present invention includes: a light source ( | 05-21-2015 |
20150025138 | IRON (III) CITRATE, SUBSTANTIALLY FREE OF BETA-IRON HYDROXIDE OXIDE - This invention provides a method for producing high-purity iron(III) citrate substantially free of beta-iron hydroxide oxide, high-purity iron(III) citrate substantially free of beta-iron hydroxide oxide, and medical uses thereof. | 01-22-2015 |
20150013703 | CARBON HEAT SOURCE AND FLAVOR INHALER - A carbon heat source ( | 01-15-2015 |
20140364493 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION - The present invention aims at provision of a method for inhibiting remnant lipoprotein production and a remnant lipoprotein production inhibitor, which includes administering a compound having a CETP inhibitory activity to an administration subject. The remnant lipoprotein production inhibitor of the present invention contains a compound having a CETP inhibitory activity as an active ingredient. | 12-11-2014 |
20140364389 | Combination Therapy - The present invention relates to a combination therapy for treating an HIV infection or inhibiting integrase comprising (S)-6-(3-Chloro-2-fluorobenzyl)-1-(1-hydroxymethyl-2-methylpropyl)-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (“Compound A”) or a pharmaceutically acceptable solvate or salt thereof in combination with at least one other anti-HIV agent. In some embodiments of the present invention, the other anti-HIV agents are chosen from reverse transcriptase inhibitors and protease inhibitors. In certain embodiments of the present invention, the other anti-HIV agents are chosen from AZT, 3TC, PMPA, efavirenz, indinavir, nelfinavir, a combination of AZT/3TC, and a combination of PMPA/3TC. Since Compound A has a high inhibitory activity specific for integrases, when used in combinations with other anti-HIV agents it can provide a combination therapy with fewer side effects for humans. | 12-11-2014 |
20140356429 | TABLET CONTAINING FERRIC CITRATE - The present invention provides a new preparation which is a tablet containing (1) ferric citrate, (2) a polyvinyl alcohol-polyethylene glycol graft copolymer, and (3) a polyvinyl alcohol-acrylic acid-methyl methacrylate copolymer | 12-04-2014 |
20140343034 | Skin barrier function improving agent - [PROBLEM] The problem to be solved by the invention is to provide a novel pharmaceutical use of a JAK inhibitor. | 11-20-2014 |
20140296316 | HYDRATE AND CRYSTAL OF FLUORENE COMPOUNDS - A compound represented by the formula (J): | 10-02-2014 |
20140296315 | PYRAZOLE-AMIDE COMPOUNDS AND PHARMACEUTICAL USE THEREOF - A compound represented by the following formula: | 10-02-2014 |
20140296306 | AMIDE COMPOUND AND MEDICINAL USE THEREOF - A compound of formula [I-W]: | 10-02-2014 |
20140243414 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS - The invention provides pharmaceutical compositions comprising a cholesteryl ester transfer protein (CETP) inhibitor and a water-insoluble concentration-enhancing additive, which exhibit improved bioavailability. The invention also provides methods of treating cardiovascular disorders comprising the administration of the pharmaceutical compositions comprising a CETP inhibitor. | 08-28-2014 |
20140242620 | METHOD OF INHIBITING NON-SPECIFIC BINDING IN STEP OF DETECTING SUBSTANCE IN BIOLOGICAL SAMPLE, AND AGENT FOR USE IN THE METHOD - The present invention provides a method of inhibiting non-specific binding in a step of detecting a substance in a biological sample. The invention provides a method of inhibiting non-specific binding in a step of detecting a substance in a biological sample, the method comprising:
| 08-28-2014 |
20140238877 | PACKAGE OF SMOKING ARTICLES WITH A SLIDING OPENING AND A HINGED LID - A package ( | 08-28-2014 |
20140221380 | SUBSTITUTED SPIROPYRIDO[1,2-a]PYRAZINE DERIVATIVE AND PHARMACEUTICAL USE OF SAME AS HIV INTEGRASE INHIBITOR | 08-07-2014 |
20140221378 | SUBSTITUTED SPIROPYRIDO[1,2-a]PYRAZINE DERIVATIVE AND PHARMACEUTICAL USE OF SAME AS HIV INTEGRASE INHIBITOR - Provided is a substituted spiropyrido[1,2-a]pyrazine derivative or a pharmaceutically acceptable salt thereof, which is useful as an anti-HIV agent. The present invention relates to a compound represented by the following formula [I] or [II] or a pharmaceutically acceptable salt thereof: | 08-07-2014 |
20140216486 | CIGARETTE MAINSTREAM SMOKE COMPONENT ADSORBENT AND CIGARETTE FILTER - The present invention provides a cigarette mainstream smoke component adsorbent including particulate activated carbon, and a glucan film supported by the particulate activated carbon. Also, the present invention provides a cigarette filter including the cigarette mainstream smoke component adsorbent. | 08-07-2014 |
20140187534 | NITROGEN-CONTAINING SPIROCYCLIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF - A compound of the following general formula [I]: | 07-03-2014 |
20140168653 | BAND DETECTION SENSOR AND DETECTION METHOD THEREFOR - A band detection sensor includes LEDs configured to radiate detection light onto one side of a web, photodiodes configured to receive the detection light reflected by the web and output a detection signal corresponding to the detection light, and a discrimination section configured to discriminate bands on the web on the basis of the detection signal from the photodiodes, wherein the discrimination section includes a rise discriminating criterion indicating a rate of rise of the detection signal and generates a band signal indicative of the presence of a band when change of the detection signal fulfills the rise discriminating criterion. | 06-19-2014 |
20140123991 | FLAVORANT-CARRYING ADSORBENT PARTICLE, CIGARETTE FILTER, FILTER-TIPPED CIGARETTE, AND METHOD FOR PRODUCING FLAVORANT-CARRYING ADSORBENT PARTICLE - A flavorant-carrying adsorbent particle comprising an adsorbent core particle having a BET specific surface area of 700 m | 05-08-2014 |
20140121229 | COMBINATION COMPRISING S-[2-([[1-(2-ETHYLBUTYL)CYCLOHEXYL] CARBONYL]AMINO)PHENYL] 2-METHYLPROPANETHIOATE AND AN HMG COA REDUCTASE INHIBITOR - The invention provides a combination comprising (a) S-[2-([[1-(2-ethylbutyl)cyclohexyl]carbonyl]amino)phenyl]2-methylpropanethioate or prodrug of the active form thereof, and (b) at least one HMG CoA reductase inhibitor. Also provided are a pharmaceutical composition, package, and a kit comprising the aforementioned active ingredients, as well as a method for treatment and prophylaxis of a cardiovascular disorder involving the use of the aforementioned active ingredients. | 05-01-2014 |
20140109905 | AEROSOL INHALATOR - An aerosol inhalator of the invention has an inner tube ( | 04-24-2014 |
20140101960 | DRYING DEVICE AND CIGARETTE WRAPPING PAPER MANUFACTURING MACHINE USING THE DRYING DEVICE - A drying device has a travel path ( | 04-17-2014 |
20140034571 | FILTER MANUFACTURING MACHINE, FILTER MANUFACTURING METHOD USING THE MACHINE, AND HOLLOW FILTER - A filter manufacturing machine includes a forming device for forming filter tow into a hollow rod-shaped continuous filter body, a forming tube included in the forming device and having a tubular forming path through which the filter tow is passed while being brought together, a mandrel arranged in the forming tube and forming the tubular forming path in cooperation with the forming tube, and a heat treating section included in the forming tube and configured to heat the filter tow while the filter tow passes through the tubular forming path. The mandrel has a small-diameter portion located at the inlet of the forming tube, a large-diameter portion located at the outlet of the forming tube, and a diameter expansion portion located between the small- and large-diameter portions. The diameter expansion portion is located downstream of the heat treating section as viewed in the moving direction of the filter tow. | 02-06-2014 |
20140027325 | PACKAGE FOR ORAL TOBACCO PRODUCT AND THE ORAL TOBACCO PRODUCT - A package for an oral tobacco product is a package that houses a pouch P including tobacco microparticles made of a tobacco raw material and a packaging material for packaging the tobacco microparticles and configured to cause, when being put in an oral cavity of a user, the user to absorb a tobacco component of the tobacco microparticles, the package including, in the inside thereof, a liquid storing section | 01-30-2014 |
20140026908 | CIGARETTE - A cigarette includes a tobacco rod, and a filter comprising a first filter plug on a tobacco rod side connected to an end of the tobacco rod, a second filter plug on a cigarette end side, and a flavor capsule arranged between the first and second filter plugs or in the second filter plug. The first filter plug has a ventilation hole, and ventilation resistance of the second filter plug is lower than that of the first filter plug. | 01-30-2014 |
20140026906 | METHOD AND APPARATUS FOR EXPANDING TOBACCO MATERIAL - A tobacco material expansion method includes the steps of wetting and swelling a tobacco material by bringing the tobacco material into contact with a water vapor stream at 100 to 160° C., and drying the tobacco material by bringing the wetted swelled tobacco material into contact with a superheated water vapor stream at a temperature higher than that of the water vapor. | 01-30-2014 |
20140020695 | METHOD OF MANUFACTURING CUT STEM, CUT STEM MANUFACTURING APPARATUS, AND CUT STEM - Method of manufacturing a cut stem with increased filling capacity comprises tearing a rod-like stem material having a water content of 20 to 50% by weight, shredding the torn rod-like stem material, and subjecting the rod-like cut stem material to expansion treatment. | 01-23-2014 |
20140020692 | ORAL TOBACCO AND METHOD FOR MANUFACTURING THE SAME - An oral tobacco raw material is easily handled during the manufacturing of oral tobacco, does not stain a packaging material when packaged as a pouch, and does not cause a feeling of a lump to a user and rapidly emits flavor when the user uses the pouch by placing it in the oral cavity. A method for manufacturing such an oral tobacco raw material, and a method for stably obtaining oral tobacco at low cost using the oral tobacco raw material are disclosed. A raw material chip for oral tobacco, includes a tobacco raw material composition including tobacco particles, water, and an additive, and a water-soluble edible film, the tobacco raw material composition and the water-soluble edible film being laminated, wherein outer surfaces of the raw material chip for oral tobacco are composed of a surface composed of the tobacco raw material composition, and a surface composed of the film. | 01-23-2014 |
20140014123 | METHOD OF MANUFACTURING RECONSTITUTED TOBACCO MATERIAL AND APPARATUS - A reconstituted tobacco material is manufactured by extracting a natural tobacco material with an extracting solvent to obtain an extraction residue and a tobacco extracted liquid containing desired components and undesired components including tobacco-specific nitrosamines, subjecting the tobacco extracted liquid to a fractionating treatment by means of a reverse osmosis membrane to obtain a membrane impermeable fraction containing the desired components and depleted in the undesired components and a membrane permeable fraction depleted in the desired components and enriched in the undesired components, controlling the tobacco extracted liquid during the fractionating treatment to have a temperature suitable for the fractionating treatment, removing precipitates, which are precipitated in the tobacco extracted liquid during the fractionating treatment, from the tobacco extracted liquid, preparing a reconstituted tobacco web containing the extraction residue, and adding the membrane impermeable fraction to the reconstituted tobacco web. | 01-16-2014 |
20130345462 | PROCESS FOR PRODUCTION OF 4-OXOQUINOLINE COMPOUND - The present invention provides a compound useful as a synthetic intermediate for an anti-HIV agent having an integrase inhibitory activity, a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate. Specifically, the present invention provides, for example, compounds represented by the formulas (6), (7-1), (7-2) and (8): | 12-26-2013 |
20130341380 | METHOD OF FORMING SCORE LINES ON BLANK, METHOD OF MANUFACTURING PACKAGE USING SAME, AND PACKAGE - A blank forming step for forming a sheet-shaped resin blank able to be formed into a box by folding and bending, and a score line forming step of forming score lines in score line forming areas of the blank which are to be bent to form outer edges of the box, to extend in the direction in which the outer edges should extend. In the score line forming step, the score lines are formed in a manner causing grooves to be produced on the back side of each score line forming area, along the score lines, through plastic deformation. The blank therefore does not undergo tensile stress pulling on the blank to either side of each groove, and thus, does not undergo warping as a whole. The blank thus retains its sheet shape and can be steadily supplied to a packaging machine. | 12-26-2013 |
20130337987 | CIGARETTE FILTER MANUFACTURING APPARATUS AND CIGARETTE FILTER MANUFACTURING METHOD - A cigarette filter manufacturing apparatus, includes, a stuffer jet which sends a tow together with air, a tongue which molds the tow into a bar, a convergence guide which is provided in a position between the stuffer jet and the tongue, and converges the tow while guiding the tow toward the tongue, and a plurality of thread introducing tubes, intervals between which are reduced toward downstream in a position between an outlet of the stuffer jet and an introducing part of the tongue, the thread introducing tubes supplying respective threads into the tow from respective downstream distal ends. | 12-19-2013 |
20130327347 | METHOD FOR PREPARING FLAVOR-CONTAINING SHEET FOR SMOKING ARTICLE, FLAVOR-CONTAINING SHEET FOR SMOKING ARTICLE PREPARED BY THE METHOD, AND SMOKING ARTICLE COMPRISING THE SAME - A method for preparing a flavor-containing sheet for a smoking article, characterized by comprising a step of extending a raw material slurry on a substrate, wherein the slurry contains polysaccharide consisting of gellan gum and tamarind gum, a flavor, an emulsifier and 70 to 95 wt % of water, has a weight ratio of gellan gum to tamarind gum of 1:1 to 3:1, and has a temperature of 60 to 90° C. in a sol state, a step of cooling the extended raw material slurry to a sample temperature of 0 to 40° C. to form a gel, and a heat-drying step comprising heating the gelled raw material and drying it at a sample temperature of 70 to 100° C. | 12-12-2013 |
20130327346 | METHOD FOR PREPARING FLAVOR-CONTAINING SHEET FOR SMOKING ARTICLE, FLAVOR-CONTAINING SHEET FOR SMOKING ARTICLE PREPARED BY THE METHOD, AND SMOKING ARTICLE COMPRISING THE SAME - A method for preparing a flavor-containing sheet for a smoking article, characterized by includes a step of extending a raw material slurry on a substrate, wherein the slurry contains polysaccharide including at least one of carrageenan and gellan gum, a flavor, an emulsifier and 70 to 95 wt % of water, has the flavor content of 100 to 1000 wt % based on the polysaccharide, and has a temperature of 60 to 90° C. in a sol state, a step of cooling the extended raw material slurry to a sample temperature of 0 to 40° C. to form a gel, and a heat-drying step includes heating the gelled raw material and drying it at a sample temperature of 70 to 100° C. | 12-12-2013 |
20130319430 | METHOD FOR PREPARING FLAVOR-CONTAINING SHEET FOR SMOKING ARTICLE, FLAVOR-CONTAINING SHEET FOR SMOKING ARTICLE PREPARED BY THE METHOD, AND SMOKING ARTICLE COMPRISING THE SAME - A method for preparing a flavor-containing sheet for a smoking article, characterized by includes a step of extending a raw material slurry on a substrate, wherein the slurry contains polysaccharide and a flavor, has a moisture content of 70 to 95 wt %, and has a temperature of 60 to 90° C. in a sol state, a step of cooling the extended raw material slurry to a sample temperature of 0 to 40° C. to form a gel, and a heat-drying step includes heating the gelled raw material and drying it at a sample temperature of 70 to 100° C. | 12-05-2013 |
20130317034 | COMBINATION THERAPY FOR TREATING DIABETES - Provided is a method of treating or preventing diabetes in a subject comprising administering a therapeutically effective amount of (a) a compound of formula (I) | 11-28-2013 |
20130312778 | FILTER FOR CIGARETTE AND FILTER-TIPPED CIGARETTE - A filter for a cigarette including a filter body and an flavor-releasing member which includes a flavorant carrier constituted of one or more discrete yarns and a plurality of flavor-releasing components carried by the flavorant carrier, wherein the flavor-releasing member is incorporated in the filter body, extending along a central axis of the filter body, one flavor-releasing component releases flavor different from other one or more flavor-releasing components, flavor-releasing behavior of one flavor-releasing component is different from that of other one or more flavor-releasing components, and the flavor-releasing component is a pure flavorant, a pure flavorant combined with cyclodextrin, or a pure flavorant combined with dextrin. | 11-28-2013 |
20130310595 | Method for Producing 4-Oxoquinoline Compound - The present invention provides a compound useful as a synthetic intermediate for an anti-HIV agent having an integrase inhibitory activity, and a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate. Specifically, for example, a compound represented by the formula (2′): | 11-21-2013 |
20130309765 | MODIFIED TAMAVIDIN - The present invention provides modified tamabidin 2, which is a modified biotin-binding protein comprising an amino acid sequence represented by SEQ ID NO: 2, an amino acid sequence having one or more amino acid mutations in the amino acid sequence of SEQ ID NO: 2, or an amino acid sequence having an identity of not less than 80% to the amino acid sequence of SEQ ID NO: 2 and having biotin-binding activity, wherein an asparagine residue at position 115 of SEQ ID NO: 2 is replaced with cysteine. The modified biotin-binding protein has remarkable heat resistance. | 11-21-2013 |
20130309691 | USE OF HEAT-RESISTANT BIOTIN-BINDING PROTEIN, AND SOLID SUPPORT HAVING THE PROTEIN ATTACHED THERETO - The present invention relates to a solid support having a heat-resistant biotin-binding protein attached thereto. The present invention also relates to the use of the solid support of the present invention having a heat-resistant biotin-binding protein attached thereto. The present invention further relates to technical fields such as purification, concentration, detection and/or capture of a biotin-linked substance by means of a heat-resistant biotin-binding protein. Such a biotin-binding protein used in the solid support of the present invention is heat-resistant and is therefore useful for use in assay systems involving exposure to a temperature of 70° C. or more. | 11-21-2013 |
20130247925 | CIGARETTE PAPER AND CIGARETTE REDUCING VISIBLE SIDESTREAM SMOKE AMOUNT AND CARBON MONOXIDE AMOUNT IN MAINSTREAM SMOKE - This invention is intended to provide a cigarette paper capable of reducing both a visible sidestream smoke amount and a carbon monoxide amount in a mainstream smoke. The invention provides a cigarette paper having a grammage of 40 to 55 g/m | 09-26-2013 |
20130242292 | INSPECTION SYSTEM FOR COATED PAPER - An inspection system for coated paper includes a traveling web of paper, a coating device for forming bands on the web by applying a coating liquid in the width direction of the web such that the bands are spaced from each other in the longitudinal direction of the web at regular intervals, a drying device for drying the web having the bands, a detection unit which is arranged downstream of the coating device for detecting at least either defect in the bands or defect in the web that is caused due to application of the coating liquid. A control device is inputted with the detection result from the detection unit and includes a determination section for determining the type of defect from the detection result. A quality control unit is inputted with the determination result from the determination section and configured to manage the determination result. | 09-19-2013 |
20130228188 | MENTHOL-SORBED ACTIVATED CHARCOAL, CIGARETTE FILTER, AND FILTER-TIPPED CIGARETTE - Menthol-sorbed activated charcoal stably holding menthol during storage, and smoothly releasing menthol only during passage of tobacco smoke therethrough is provided. The menthol-sorbed activated charcoal is featured in that to activated charcoal having a specific surface area of 1500 m | 09-05-2013 |
20130220353 | METHOD OF PRODUCING FLAVOR-RELEASING GRANULES, FLAVOR-RELEASING GRANULES, AND CIGARETTE FILTER CONTAINING FLAVOR-RELEASING GRANULES - A method of producing flavor-releasing granules, includes adding ethanol, together with a plurality of flavorant compounds, to an aqueous solution containing a plurality of cyclodextrin compounds and conducting stirring to include the flavorant compounds within the cyclodextrin compounds, intermittently spraying the obtained aqueous solution onto hygroscopic core particles in a state of planetary motion to adhere the flavorant inclusion cyclodextrin compounds to the respective surfaces of the core particles. | 08-29-2013 |
20130217044 | FACTOR INVOLVED IN LATENT INFECTION WITH HERPESVIRUS, AND USE THEREOF - Disclosed are a protein and a gene each of which is a factor involved in latent infection with a herpesvirus. An antibody against the factor was detected in approximately 50% of patients suffering from mental disorders, whereas the antibody was hardly detected in healthy persons. Further, a mouse having SITH-1 introduced therein developed a mental disorder such as a manic-depressive illness or depression-like disorder. Based on these findings, it is possible to provide a method for objectively determining a mental disorder and an animal model of a mental disorder. | 08-22-2013 |
20130215259 | CIGARETTE INSPECTION APPARATUS - To analyze an inspection image obtained by taking an image of filter end faces of filter cigarettes horizontally arranged, from an axial direction, and thus inspect an excess cigarette feeding error, there are provided a first judging device that the number of cigarettes according to shape information of the filter end faces obtained from the inspection image, and a second judging device that obtains the centroid positions of the filter end faces from the inspection image, and detects that there is an excess feeding error when difference between a maximum value and a minimum value of the centroid-to-centroid distance of adjacent filter end faces is substantially equal to a previously-known diameter of the filter end face. | 08-22-2013 |
20130199550 | CIGARETTE AND PRODUCTION METHOD THEREOF - A cigarette comprising a tobacco rod comprising a tobacco filler and a cigarette paper which is wrapped around the tobacco filler, a filter comprising a filter member and a filter wrapping paper which is integrally wrapped around the filter member, and a tipping member which is bonded onto the tobacco rod and the filter with a pressure-sensitive adhesive to connect the tobacco rod and the filter. | 08-08-2013 |
20130172344 | 4-OXOQUINOLINE COMPOUND AND USE THEREOF AS HIV INTEGRASE INHIBITOR - An anti-HIV agent containing, as an active ingredient, a 4-oxoquinoline compound represented by the following formula [I] | 07-04-2013 |
20130160780 | NON-HEATING TYPE FLAVOR INHALATOR AND METHOD OF MANUFACTURING FLAVOR CARTRIDGE - A non-heating type flavor inhalator of the invention includes a hollow cylindrical holder ( | 06-27-2013 |
20130160779 | TOBACCO-FLAVOR-RELEASING MATERIAL AND NON-HEATING TYPE TOBACCO FLAVOR INHALATOR CONTAINING SAME - A tobacco-flavor-releasing material includes granules which contain (a) a ground tobacco material, (b) water, (c) a moisturizing agent includes a polyhydric alcohol, (d) at least one pH-adjusting agent selected from the group consisting of potassium carbonate and sodium hydrogencarbonate, and (e) at least one binder selected from the group consisting of pullulan and hydroxypropyl cellulose. | 06-27-2013 |
20130137088 | FACTOR INVOLVED IN LATENT INFECTION WITH HERPESVIRUS, AND USE THEREOF - Disclosed are a protein and a gene each of which is a factor involved in latent infection with a herpesvirus. An antibody against the factor was detected in approximately 50% of patients suffering from mental disorders, whereas the antibody was hardly detected in healthy persons. Further, a mouse having SITH-1 introduced therein developed a mental disorder such as a manic-depressive illness or depression-like disorder. Based on these findings, it is possible to provide a method for objectively determining a mental disorder and an animal model of a mental disorder. | 05-30-2013 |
20130133675 | SMOKELESS FLAVOR INHALATOR - A smokeless flavor inhalator includes a tobacco material as a flavor generator, and a heater for heating the tobacco material to allow flavor components to be released from the tobacco material while preventing smoke from being generated from the tobacco material. The heater has a carbon heat source and a cooling element. The carbon heat source and the cooling element cooperatively keep the heating temperature of the tobacco material at a temperature of 50 to 200° C. | 05-30-2013 |
20130133673 | TOBACCO PRODUCT - A tobacco product produced by wrapping cut tobacco with a pouch or a cigarette paper, wherein the pouch or the cigarette paper has an inner layer and an outer layer, and a paper of the outer layer has an air permeability higher than that of a paper of the inner layer. | 05-30-2013 |
20130125265 | AGROBACTERIUM-MEDIATED METHOD FOR PRODUCING TRANSFORMED PLANT - The present invention aims to provide a novel | 05-16-2013 |
20130122566 | NOVEL ENZYME PROTEIN, PROCESS FOR PRODUCTION OF THE ENZYME PROTEIN THE SAME, AND GENE ENCODING THE ENZYME PROTEIN THE SAME - The present invention relates to a protein having a β-galactoside-α2,3-sialyltransferase activity but substantially not having any neuraminidase activity, a nucleic acid encoding the enzyme protein, and a method of producing the enzyme using a microorganism transformed with a gene encoding the protein. The protein of the present invention is a modified-type enzyme protein produced by mutating a specific amino acid residue in a β-galactoside-α2,3-sialyltransferase protein derived from a microorganism belonging to the genus | 05-16-2013 |
20130116240 | INDOLE COMPOUNDS AND PHARMACEUTICAL USE THEREOF - Provided is an agent for the treatment or prophylaxis of inflammatory diseases, allergic diseases, autoimmune diseases, transplant rejection or the like. | 05-09-2013 |
20130113917 | CIGARETTE INSPECTION APPARATUS - An image of the filter end faces of a bundle of cigarettes arranged side by side with axes thereof paralleled is acquired as an inspection image, and the diameters of the individual cigarettes of the bundle in the inspection image are obtained and compared with normal diameters associated with the respective cigarettes in the inspection image, to determine axial displacement of cigarettes from the bundle (first determination section). Also, the centers of gravity of the end faces of the individual cigarettes are obtained, and based on the difference between an inter-center-of-gravity distance which is the distance between an outermost cigarette in the bundle and its adjacent cigarette, and an inter-center-of-gravity distance which is the distance between adjacent cigarettes located in the central part of the bundle and belonging to the same tier as the outermost cigarette, axial displacement of the outermost cigarettes is determined (second determination section). | 05-09-2013 |
20130109710 | SPIRO COMPOUNDS AND PHARMACEUTICAL USE THEREOF | 05-02-2013 |
20130096155 | TRIAZOLOPYRIDINE COMPOUND, AND ACTION THEREOF AS PROLYL HYDROXYLASE INHIBITOR OR ERYTHROPOIETIN PRODUCTION-INDUCING AGENT - The present invention provides a triazolopyridine compound having a prolyl hydroxylase inhibitory action and an erythropoietin production-inducing ability. The present invention relates to a compound represented by the following formula [I]: | 04-18-2013 |
20130091599 | Cosmid Vector for Transforming Plant and Use Thereof - The present invention provides novel cosmid vectors for plant transformation. The cosmid vectors have a full length of 15 kb or less and contain: 1) an origin of replication of an IncP plasmid, but not any origin of replication of other plasmid groups; 2) the trfA1 gene of an IncP plasmid; 3) an oriT of an IncP plasmid; 4) the incC1 gene of an IncP plasmid; 5) a cos site of lambda phage, which is located outside the T-DNA; 6) a drug resistance gene expressed in | 04-11-2013 |
20130085132 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF - The present invention provides a pyrazole compound of the following general Formula [Ib] having SGLT1 inhibitory activity, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the same, and its pharmaceutical use: | 04-04-2013 |
20130081644 | CIGARETTE FILTER AND CIGARETTE - A cigarette filter includes filter plugs separated from each other and arranged through a cavity, a flavor capsule encapsulating a content liquid including a flavor in a shell and provided in the cavity between the filter plugs, and a liquid-impermeable tipping paper and/or filter wrapper wrapped around the filter plugs and the flavor capsule, wherein the content liquid comprises the flavor and a thickener and has a viscosity of 30 mPa·s or more. | 04-04-2013 |
20130053417 | CETP ACTIVITY INHIBITORS - The invention provides a compound that is a CETP activity inhibitor. The compound can increase HDL and at the same time decrease LDL through selective inhibition of CETP activity, the invention also provides for the use of the compound to prevent or treat atherosclerosis or hyperlipidemia. | 02-28-2013 |
20130019888 | SMOKING ARTICLE - A smoking article comprises a multilayered tube member ( | 01-24-2013 |
20130019884 | CIGARETTE WITH INCREASED VOLATILE FLAVOR DELIVERY - A cigarette includes a tobacco rod in which a tobacco filler containing cut tobacco is wrapped with a cigarette paper, the tobacco rod being constituted by a distal end portion, a proximal end portion and a center portion, and a filter, the proximal end portion being connected to the filter. The distal end portion includes a volatile flavor-containing material incorporated in a gel of a polysaccharide, the center portion includes or does not include the volatile flavor-containing material, the proximal end portion includes or does not include the volatile flavor-containing material, and there is no case where both the center portion and the proximal end portion include the volatile flavor-containing material. | 01-24-2013 |
20120322837 | AMIDE COMPOUND AND MEDICINAL USE THEREOF - A compound of formula [I-W]: | 12-20-2012 |
20120301552 | CaSR Antagonist - A compound represented by the following formula (1), a pharmaceutically acceptable salt thereof or an optically active form thereof: | 11-29-2012 |
20120238622 | IRON (III) CITRATE, SUBSTANTIALLY FREE OF BETA-IRON HYDROXIDE OXIDE - This invention provides a method for producing high-purity iron(III) citrate substantially free of beta-iron hydroxide oxide, high-purity iron(III) citrate substantially free of beta-iron hydroxide oxide, and medical uses thereof. | 09-20-2012 |
20120121703 | TABLET CONTAINING FERRIC CITRATE - The present invention provides a new preparation which is a tablet containing (1) ferric citrate, (2) a polyvinyl alcohol-polyethylene glycol graft copolymer, and (3) a polyvinyl alcohol-acrylic acid-methyl methacrylate copolymer. | 05-17-2012 |
20120115827 | 3-AMINOBENZAMIDE COMPOUNDS AND VANILLOID RECEPTOR SUBTYPE 1 (VR1) INHIBITORS - The present invention relates to a novel 3-aminobenzamide, compound represented by the following formula which effectively inhibits vanilloid receptor subtype 1 (VR1) activity (wherein, for example, R | 05-10-2012 |
20120107273 | NEW PIPERAZINE COMPOUND AND USE THEREOF AS A HCV POLYMERASE INHIBITOR - The present invention relates to a compound represented by the following formula [I] | 05-03-2012 |
20120090799 | METHOD AND APPARATUS FOR MANUFACTURING CIGARETTE WRAPPING PAPER - Web to be formed into wrapping paper is applied with combustion inhibitor and then dried. Water is applied onto the entire surface of the opposite side to the combustion-inhibitor applied side of the web. The web applied with water is dried while pinched between drying and pressing rollers and stretched in a width direction. In this way, unwrinkled high-quality cigarette wrapping paper having a low ignition propensity can be stably and inexpensively manufactured. As the pressing roller, a heat-resistant rubber roller provided in its surface with a soft portion in a helical way is utilized. | 04-19-2012 |
20120070409 | TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR - The present invention relates to a tetracyclic fused heterocyclic compound represented by the following formula [I] | 03-22-2012 |
20120064543 | METHOD FOR DETECTING SUBSTANCE IN BIOLOGICAL SAMPLE - The present invention provides a method for detecting a substance in a biological sample, a carrier for using in the method, and a kit. The method of the present invention according to an embodiment includes:
| 03-15-2012 |
20120039874 | HUMAN MONOCLONAL ANTIBODY AGAINST A COSTIMULATORY SIGNAL TRANSDUCTION MOLECULE AILIM AND PHARMACEUTICAL USE THEREOF - Immunization of human antibody-producing transgenic mice, which have been created using genetic engineering techniques, with AILIM molecule as an antigen resulted in various human monoclonal antibodies capable of binding to AILIM and capable of controlling a variety of biological reactions (for example, cell proliferation, cytokine production, immune cytolysis, cell death, induction of ADCC, etc.) associated with AILIM-mediated costimulatory signal (secondary signal) transduction. Furthermore, it has been revealed that the human monoclonal antibody is effective to treat and prevent various diseases associated with AILIM-mediated costimulatory signal transduction, being capable of inhibiting the onset and/or advancement of the diseases. | 02-16-2012 |
20120020920 | 5-5-MEMBERED FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR - The present invention relates to a fused ring compound represented by the following formula [I] | 01-26-2012 |
20120003231 | CELL SURFACE MOLECULE MEDIATING CELL ADHESION AND SIGNAL TRANSMISSION - Novel cell surface molecules recognized by monoclonal antibodies against a cell surface molecule of lymphocytic cells that play an important role in autoimmune diseases and allergic diseases have been isolated, identified, and analyzed for their functions. The cell surface molecules are expressed specifically in thymocytes, lymphocytes activated by ConA-stimulation, and peripheral blood lymphocytes, and induce cell adhesion. Antibodies against the cell surface molecules significantly ameliorate pathological conditions of autoimmune diseases and allergic diseases. | 01-05-2012 |
20110306599 | INDOLE COMPOUNDS AND PHARMACEUTICAL USE THEREOF - Provided is an agent for the treatment or prophylaxis of inflammatory diseases, allergic diseases, autoimmune diseases, transplant rejection or the like. | 12-15-2011 |
20110277181 | DROUGHT TOLERANT PLANTS AND RELATED CONSTRUCTS AND METHODS INVOLVING GENES ENCODING DTP21 POLYPEPTIDES - Isolated polynucleotides and polypeptides and recombinant DNA constructs useful for conferring drought tolerance, compositions (such as plants or seeds) comprising these recombinant DNA constructs, and methods utilizing these recombinant DNA constructs. The recombinant DNA construct comprises a polynucleotide operably linked to a promoter that is functional in a plant, wherein said polynucleotide encodes a DTP21 polypeptide. | 11-10-2011 |
20110245223 | HETEROCYCLIC COMPOUNDS - The present invention provides a compound represented by the following formula [1′] or a salt thereof: | 10-06-2011 |
20110212952 | 3,4-DIHYDROBENZOXAZINE COMPOUNDS AND INHIBITORS OF VANILLOID RECEPTOR SUBTYPE 1 (VRI) ACTIVITY - A 3,4-dihydrobenzoxazine compound of the present invention is represented by the following formula [1] (wherein X is a nitrogen atom or CR | 09-01-2011 |
20110192408 | NON-COMBUSTION FLAVOR INHALATION ARTICLE - A non-combustion flavor inhalation article includes a heating device including a heater to be heated to a temperature between 80 and 140° C., and a roll including a tobacco sheet to be disposed in contact with the heater. | 08-11-2011 |
20110189210 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION - The present invention aims at provision of a method for inhibiting remnant lipoprotein production and a remnant lipoprotein production inhibitor, which includes administering a compound having a CETP inhibitory activity to an administration subject. The remnant lipoprotein production inhibitor of the present invention contains a compound having a CETP inhibitory activity as an active ingredient. | 08-04-2011 |
20110178944 | SYSTEM FOR CALCULATING THE NUMBER OF DELIVERY ROUTES, AND METHOD FOR CALCULATING THE NUMBER OF DELIVERY ROUTES - The necessary number of delivery routes is accurately calculated corresponding to properties of an area. A system | 07-21-2011 |
20110136778 | NITROGEN-CONTAINING SPIROCYCLIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF - A compound of the following general formula [I]: | 06-09-2011 |
20110107469 | NOVEL PROTEIN, A GENE ENCODING THEREFOR AND A METHOD OF USING THE SAME - An object of the present invention is to search and identify novel antifungal proteins capable of inhibiting the growth of plant pathogenic microorganisms including | 05-05-2011 |
20110077267 | TRIAZOLOPYRIDINE COMPOUND, AND ACTION THEREOF AS PROLYL HYDROXYLASE INHIBITOR OR ERYTHROPOIETIN PRODUCTION-INDUCING AGENT - The present invention provides a triazolopyridine compound having a prolyl hydroxylase inhibitory action and an erythropoietin production-inducing ability. The present invention relates to a compound represented by the following formula [I]: | 03-31-2011 |
20110053250 | ENRICHMENT METHOD OF VIRUS - The present invention provides a novel method that can increase readily a virus or viral vector concentration in a solution having a low concentration and a kit for performing the method. Conventional methods require complicated operations, expensive equipment, or highly trained experts for efficiently concentrating viruses from low-concentration virus solutions. The method of the present invention can concentrate viral vectors readily while maintaining infection abilities of the viral vectors, and thus it can be used as a safe and simple technique for concentrating a vector useful in the field of a genetic therapy or a vaccine therapy using a viral vector. | 03-03-2011 |
20110053145 | QUANTITATION METHOD OF VIRUS - The present invention relates to a method of quantitatively determining the number of human herpesvirus (HHV) collected from a body fluid and a kit for performing the method. Conventionally, a trained technician has been required to accurately quantitatively determine a number of HHV collected from a body fluid. The method of the present invention is a novel method of quantitative determination that enables measurement of a number of HHV in a body fluid to be simply, accurately, and efficiently determined. The method of the present invention can enable continuous evaluation of the number of HHV in body fluids and, therefore, can be applied to quantitative evaluation of the accumulation of fatigue. | 03-03-2011 |
20100331301 | AZETIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF - Compounds of formula [I]: | 12-30-2010 |
20100330701 | USE OF HEAT-RESISTANT BIOTIN-BINDING PROTEIN, AND SOLID SUPPORT HAVING THE PROTEIN ATTACHED THERETO - The present invention relates to a solid support having a heat-resistant biotin-binding protein attached thereto. The present invention also relates to the use of the solid support of the present invention having a heat-resistant biotin-binding protein attached thereto. The present invention further relates to technical fields such as purification, concentration, detection and/or capture of a biotin-linked substance by means of a heat-resistant biotin-binding protein. Such a biotin-binding protein used in the solid support of the present invention is heat-resistant and is therefore useful for use in assay systems involving exposure to a temperature of 70° C. or more. | 12-30-2010 |
20100305958 | DATA PROCESSING SYSTEM, COMPUTER PROGRAM USED THEREFOR, AND DATA PROCESSING METHOD - A temperature sensing unit senses a plurality of specific temperatures caused by a specific consumable commodity consumed by an ordinary consumer at a specific space, while allowing a behavior storage unit to store q plurality of combinations of the plurality of specific temperatures as a plurality of consumption behaviors of the specific consumable commodity by ordinary consumers. A behavior specifying unit specifies consumption behaviors which match a combination of the plurality of specific temperatures sensed for each piece of the specific consumable commodity, and a data collection unit compiles the specified consumption behavior. Accordingly, data regarding the consumption behaviors of the ordinary consumers, which are uncollectible at the points of time of order intake, production, shipping and selling and so forth of the specific consumable commodity, can be collected. A data processing system capable of efficiently collecting data regarding the consumption behaviors of the specific consumable commodity, such as a cigarette, may be provided. | 12-02-2010 |
20100291631 | Novel Beta-Galactoside-Alpha 2,3-Sialyltransferase, a Gene Encoding Thereof, and a Method for Producing Thereof - The present invention provides a novel β-galactoside-α2,3-sialyltransferase and a nucleic acid encoding the sialyltransferase. The present invention also provides a microorganism producing the sialyltransferase, as well as a method for producing the sialyltransferase using such a microorganism. The present invention further provides a vector carrying a nucleic acid encoding the sialyltransferase, and a host cell transformed with the vector, as well as a method for producing a recombinant β-galactoside-α2,3-sialyltransferase. The present invention further provides a method for preparing a sialylsugar chain, which uses the sialyltransferase of the present invention. | 11-18-2010 |
20100286416 | PRODUCTION METHOD OF CARBOXYLIC ACID COMPOUND - The present invention provides the production method of carboxylic acid compound, as shown in Scheme I. | 11-11-2010 |
20100240634 | Fluorene Compound and Pharmaceutical Use Thereof - The present invention provides an agent for the prophylactic or treatment of diabetes, diabetic complications, insulin resistance syndrome, metabolic syndrome, hyperglycemia, dyslipidemia, atherosclerosis, cardiac failure, cardiomyopathy, myocardial ischemia, brain ischemia, cerebral apoplexy, pulmonary hypertension, hyperlactacidemia, mitochondrial disease, mitochondrial encephalomyopathy or cancer, namely, a PDHK inhibitor and the like. A compound represented by the following formula [I] or a pharmaceutically acceptable salt thereof, or a solvate thereof: | 09-23-2010 |
20100240613 | PYRIMIDINE COMPOUND AND MEDICAL USE THEREOF - The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] | 09-23-2010 |
20100197736 | CETP ACTIVITY INHIBITORS - The present invention provides a CETP activity inhibitor comprising as an active ingredient a compound represented by the formula (I): | 08-05-2010 |
20100132068 | Cosmid Vector For Plant Transformation And Use Thereof - The present invention aims to provide novel vectors for plant transformation. | 05-27-2010 |
20100132066 | AGROBACTERIUM-MEDIATED METHOD FOR PRODUCING TRANSFORMED PLANT WITHOUT SELECTION STEP - The present invention aims to provide a novel | 05-27-2010 |
20100112616 | NOVEL BETA-GALACTOSIDE-a2,6-SIALYLTRANSFERASE, A GENE ENCODING THEREOF, AND A METHOD FOR ENHANCING ENZYME ACTIVITY - The present invention provides an extremely useful and novel β-galactoside-α2,6-sialyltransferase having an optimum reaction pH in a neutral to alkaline range, and a nucleic acid encoding the sialyltransferase. The present invention further provides a vector carrying a nucleic acid encoding the sialyltransferase, and a host cell transformed with the vector, as well as a method for producing a recombinant β-galactoside-α2,6-sialyltransferase. | 05-06-2010 |
20100072150 | CIGARETTE DISPLAY SYSTEM, FRAME UNIT, TRAY UNIT, MAGAZINE UNIT, AND SLIDER UNIT - An apparatus main body of a frame structure and an apparatus main body of a wall structure are formed separately, tray units | 03-25-2010 |
20100068812 | METHOD FOR INCREASING TRANSFORMATION EFFICIENCY IN PLANTS, COMPRISING COCULTURE STEP FOR CULTURING PLANT TISSUE WITH COCULTURE MEDIUM CONTAINING 3, 6-DICHLORO-O-ANISIC ACID - The present invention aims to provide a method for increasing transformation efficiency in plants when compared to conventionally known | 03-18-2010 |
20100025345 | CIGARETTE DISPLAY SYSTEM - A cigarette display system | 02-04-2010 |
20100022523 | 3-AMINOBENZAMIDE COMPOUNDS AND VANILLOID RECEPTOR SUBTYPE 1 (VR1) INHIBITORS - The present invention relates to a novel 3-aminobenzamide compound represented by the following formula which effectively inhibits vanilloid receptor subtype 1 (VR1) activity (wherein, for example, R | 01-28-2010 |
20100012603 | CIGARETTE DISPLAY SYSTEM - In a cigarette display system | 01-21-2010 |
20100010219 | METHOD FOR PRODUCING PYRROLIDINE COMPOUND - Provided is a method capable of efficiently producing a compound having a superior HSD1 inhibitory action and a compound useful as a synthetic intermediate therefor, with superior achievability of asymmetric synthesis (i.e., superior selectivity), superior yield, superior safety and superior industrial workability at a low cost. | 01-14-2010 |
20090326058 | CaSR Antagonist - A compound represented by the following formula (1), a pharmaceutically acceptable salt thereof or an optically active form thereof: | 12-31-2009 |
20090301506 | LOW IGNITION PROPENSITY CIGARETTE, WRAPPING PAPER THEREFOR, AND METHOD OF PRODUCING WRAPPING PAPER - A low ignition propensity cigarette has wrapping paper ( | 12-10-2009 |
20090291471 | Novel Beta-Galactoside Alpha 2,6-Sialyltransferase, Gene Coding For The Transferase And Process For Producing The Same - The present invention provides a novel β-galactoside-α2,6-sialyltransferase having high productivity and/or high activity, and a nucleic acid encoding the sialyltransferase. The present invention also provides a microorganism producing the sialyltransferase. The present invention further provides a vector carrying a nucleic acid encoding the sialyltransferase, and a host cell transformed with the vector, as well as a method for producing a recombinant β-galactoside-α2,6-sialyltransferase. | 11-26-2009 |
20090221635 | QUINOLINYL AND BENZOTHIAZOLYL MODULATORS - Compounds, compositions and methods are provided that are useful in the treatment or prevention of a condition or disorder mediated by PPARγ. In particular, the compounds of the invention modulate the function of PPARγ. The subject methods are particularly useful in the treatment and/or prevention of diabetes, obesity, hypercholesterolemia, rheumatoid arthritis and atherosclerosis. | 09-03-2009 |
20090170908 | SPIRO COMPOUNDS AND PHARMACEUTICAL USE THEREOF - The Spiro compound represented by the following general formula [Ia], its pharmaceutically acceptable salt or a solvate thereof | 07-02-2009 |
20090155273 | REMEDIES FOR INFLAMMATORY BOWEL DISEASES - Antibodies against AILIM (also called ICOS and 8F4) were found to significantly suppress the onset of inflammatory bowel diseases (especially Crohn's disease and colitis (ulcerative colitis and such)), and exhibit a significant therapeutic effect against inflammatory bowel diseases. | 06-18-2009 |
20090148444 | PHARMACEUTICAL COMPOSITION FOR TREATING IMMUNE DISEASES - An antibody against AILIM (alternatively called JTT-1 antigen, JTT-2 antigen, ICOS and 8F4) was found to have a significant therapeutic effect on arthrosis, for example, rheumatoid arthritis and osteoarthritis, graft versus host disease, graft immune rejection, inflammation (hepatitis and inflammatory bowel diseases), diseased condition accompanied by the excessive production of an antibody against a foreign antigen triggered by immunological sensitization by the antigen. | 06-11-2009 |
20090087894 | Method for improving enzymatic activity of glycosyltransferases - The present invention provides an inexpensive and simple method which allows efficient glycosylation with glycosyltransferases derived from microorganisms of the Vibrionaceae family when compared to conventional enzymatic reaction systems. | 04-02-2009 |
20090064575 | Method for Evaluating Deep Rooting Property of Plant - The present invention relates to a method of evaluating multiple plant individuals or plant lines for deep rooting property under the same culture medium moisture conditions. A method of the present invention is a method of evaluating multiple plant individuals for deep rooting property under the same culture medium moisture conditions, by planting multiple plant individuals together in a sufficiently deep culture vessel and lowering the culture medium moisture content gradually. The present invention also provides a method for evaluating plants for deep rooting property, wherein a culture vessel is installed in a water tank so that the culture medium moisture content can be readily adjusted, and thus management of cultivation conditions is facile and efficient. It is possible to select a plant which can grow in dry and low-groundwater level environment efficiently, by using the method of the present invention. Thus, the method of the present invention can find application in breeding a crop suitable for dry land cultivation and trees usable in desert greening. | 03-12-2009 |
20090047292 | GRAFT REJECTION SUPPRESSORS - Graft rejection is a serious problem associated with tissue or organ transplantation (e.g., allotransplantation or xenotransplantation), performed to treat various organ failures (e.g., liver, heart, lung, kidney, or pancreas). Described are pharmaceutical compositions for suppressing, treating, or preventing graft rejection comprising a substance having an activity to modulate signal transduction mediated by AILIM, and a pharmaceutically acceptable carrier. | 02-19-2009 |
20090038965 | Cigarette package and method of producing same - A cigarette package is provided with a box body ( | 02-12-2009 |
20090036450 | PYRAZOLE COMPOUNDS AND USE THEREOF - The pyrazole compound of the present invention is represented by the following general formula (I). The pyrazole compound of the present invention or a salt thereof or a solvate thereof potently inhibits liver glycogen phosphorylase, and, therefore, is useful as a therapeutic or prophylactic agent for diabetes. | 02-05-2009 |
20090036444 | 5-5-Membered fused heterocyclic compound and use thereof as HCV polymerase inhibitor - The present invention relates to a fused ring compound represented by the following formula [I] | 02-05-2009 |
20080316483 | Mixture indentification system - A mixture identification system for detecting foreign matter admixed in a tobacco material (T) includes a conveyor ( | 12-25-2008 |
20080312228 | PYRIMIDINE COMPOUND AND MEDICAL USE THEREOF - The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] | 12-18-2008 |
20080305169 | Pharmaceutical Compositions Comprising Nitrogen-Containing Fused Ring Coumpounds - [Problems] The present invention provides pharmaceutical composition which is effective for the prophylaxis or treatment of pathology showing involvement of uric acid (hyperuricemia, gouty tophus, acute gout arthritis, chronic gout arthritis, gouty kidney, urolithiasis, renal function disorder, coronary arterial disease, ischemic heart disease and the like) and the like, and is superior in the time-course stability and dissolution property (disintegration property).
| 12-11-2008 |
20080301832 | Method for Screening Genomic Dna Fragments - The present invention provides a method for selecting genomic DNA fragments which are useful for providing a plant with an agriculturally advantageous improvement. | 12-04-2008 |
20080300957 | Simulation Apparatus, Effect Measurement Apparatus, and Sales Promotion Support System - There is provided a simulation apparatus that predicts an effect of sending out a direct mail for a product of a specific brand, including a planned budget acceptance unit | 12-04-2008 |
20080255042 | CaSR Antagonist - A compound represented by the following formula (1), a pharmaceutically acceptable salt thereof or an optically active form thereof: | 10-16-2008 |
20080248031 | CELL SURFACE MOLECULE MEDIATING CELL ADHESION AND SIGNAL TRANSMISSION - Novel cell surface molecules recognized by monoclonal antibodies against a cell surface molecule of lymphocytic cells that play an important role in autoimmune diseases and allergic diseases have been isolated, identified, and analyzed for their functions. The cell surface molecules are expressed specifically in thymocytes, lymphocytes activated by ConA-stimulation, and peripheral blood lymphocytes, and induce cell adhesion. Antibodies against the cell surface molecules significantly ameliorate pathological conditions of autoimmune diseases and allergic diseases. | 10-09-2008 |
20080199466 | HUMAN MONOCLONAL ANTIBODY AGAINST A COSTIMULATORY SIGNAL TRANSDUCTION MOLECULE AILIM AND PHARMACEUTICAL USE THEREOF - Immunization of human antibody-producing transgenic mice, which have been created using genetic engineering techniques, with AILIM molecule as an antigen resulted in various human monoclonal antibodies capable of binding to AILIM and capable of controlling a variety of biological reactions (for example, cell proliferation, cytokine production, immune cytolysis, cell death, induction of ADCC, etc.) associated with AILIM-mediated costimulatory signal (secondary signal) transduction. Furthermore, it has been revealed that the human monoclonal antibody is effective to treat and prevent various diseases associated with AILIM-mediated costimulatory signal transduction, being capable of inhibiting the onset and/or advancement of the diseases. | 08-21-2008 |