Japan Science & Technology Agency Patent applications |
Patent application number | Title | Published |
20110250612 | NOVEL CENTROMERIC PROTEIN SHUGOSHIN - The present invention is to provide meiosis-specific novel kinetochore protein Sgo1 (shugoshin) derived from fission yeast | 10-13-2011 |
20100004327 | Novel Use of Ansamycin Antibiotics And Method of Screening Novel Angiogenesis Inhibitor - The present invention provides novel angiogenesis inhibitors effective, safe and highly practical for inhibition of angiogenesis in various diseases, and a method for screening the same. The active ingredients of the angiogenesis inhibitors of the present invention comprise ansamycin antibiotics such as rifampicin, rifamycin SV and 3-formyl rifamycin, which have long been used extensively as antibacterial agents for treating tuberculosis or Gram-positive bacterial infections. The active ingredients of the present invention have excellent angiogenesis-inhibiting activity. The angiogenesis inhibitor of the present invention is effective for inhibition of angiogenesis in malignant tumors, diabetic retinopathy, retinal angiogenesis, inflammatory diseases, and angiogenesis accompanying cardiovascular remodeling, etc., and can be used as therapeutic agents against each disease, etc. Further, the screening method of the present invention makes it possible to perform an effective screening of angiogenesis-inhibiting substances by detecting angiogenesis-inhibiting signals based on gene expression levels. | 01-07-2010 |
20100003194 | INHIBITOR SCREENING METHOD AND ATOPIC DERMATITIS LIKE SYMPTOM INDUCING METHOD WHICH UTILIZES INDUCTION OF PRODUCTION OF INTERLEUKIN 18 BY KERATINOCYTE AND UTILIZATION OF SAME - The present invention provides methods which use induction phenomenon of production of interleukin 18 (IL-18) from keratinocyte (KC), and their usages. The methods are preferably applicable for understanding of pathogenic mechanisms of atopic dermatitis (AD) and AD-like symptoms, and for development of therapeutic drugs for AD and AD-like symptoms. For example, by applying, on skin of mice or the like, protein A (SpA) derived from | 01-07-2010 |
20090215994 | Novel Centromeric Protein Shugoshin - The present invention is to provide meiosis-specific novel kinetochore protein Sgo1 (shugoshin) derived from fission yeast | 08-27-2009 |
20090203887 | Novel Centromeric Protein Shugoshin - The present invention is to provide meiosis-specific novel kinetochore protein Sgo1 (shugoshin) derived from fission yeast | 08-13-2009 |