InfraReDx, Inc. Patent applications |
Patent application number | Title | Published |
20140276065 | High Resolution Intravascular Ultrasound Imaging Systems and Methods - Disclosed is a high resolution intravascular ultrasound imaging system including a catheter with a rotatable imaging assembly and an image processor. The image processor in turn features a pulser configured to energize the ultrasound transducer of the rotatable imaging assembly with a multi-frequency ultrasound waveform signal. The image processor further contains a receiver configured to decompose received ultrasound energy as reflected by the target vessel into a plurality of individual subband signals, individually process these signals and reconstitute these signals into a high resolution image of the blood vessel. The IVUS system of the invention may be useful in characterizing cap thickness of vulnerable plaques or other detailed studies of blood vessels. | 09-18-2014 |
20130053698 | DETECTION OF LIPID CORE PLAQUE CAP THICKNESS - Described are methods, systems, and apparatus, including computer program products for examining a blood vessel wall. The blood vessel wall is illuminated with near-infrared light. Reflected near-infrared light from the blood vessel wall is received. A reflectance spectrum based on the reflected near-infrared light from the blood vessel wall is determined. Whether the reflectance spectrum is indicative of a presence of a lipid core plaque (LCP) by applying an LCP classifier to the reflectance spectrum is determined. A thickness of an LCP cap is determined by applying an LCP cap thickness classifier to the reflectance spectrum if the reflectance spectrum is indicative of the presence of the LCP. Indicia of the thickness of the LCP cap are displayed. | 02-28-2013 |
20110046490 | ARTERIAL PROBE FOR OCT - An apparatus for detecting vulnerable plaque within a lumen defined by an intraluminal wall is described. The apparatus includes a probe having a distal portion and a proximal portion. The apparatus includes an optical waveguide extending along the probe. The optical waveguide is configured to carry optical radiation between the distal and proximal portions, and has a distal end in communication with the intraluminal wall. The apparatus includes an interferometer coupled to the optical waveguide and configured to provide an interference signal for sub-surface imaging of the intraluminal wall, and a processing module configured to provide spectroscopic information from detected intensity of light collected from the intraluminal wall. | 02-24-2011 |
20100217131 | MULTI-CHANNEL CATHETER TIP - A tip assembly for a catheter includes a housing having a recess that receives an optical bench. The optical bench accommodates adjacent fibers, one of which is in optical communication with a first beam re-director. The first beam re-director is oriented to cause a beam incident thereon to travel in a direction away from the optical bench. An engaging structure coupled to the optical bench provides torque coupling between the housing and an end of a torque cable extending axially along the catheter. | 08-26-2010 |
20100165353 | ARTERIAL PROBE FOR OCT - An apparatus for detecting vulnerable plaque within a lumen defined by an intraluminal wall is described. The apparatus includes a probe having a distal portion and a proximal portion. The apparatus includes an optical waveguide extending along the probe. The optical waveguide is configured to carry optical radiation between the distal and proximal portions, and has a distal end in communication with the intraluminal wall. The apparatus includes an interferometer coupled to the optical waveguide and configured to provide an interference signal for sub-surface imaging of the intraluminal wall, and a processing module configured to provide spectroscopic information from detected intensity of light collected from the intraluminal wall. | 07-01-2010 |
20100160792 | Spectroscope With Modified Field-of-View - A spectroscope for detecting vulnerable plaques includes an optical fiber extending through a catheter. The optical fiber has a field-of-view that is modified to preferentially collect light scattered from deep within the wall of a blood vessel. Obstructions or curved optical surfaces can be used to modify the field of view. | 06-24-2010 |
20100022891 | INTRALUMINAL SPECTROSCOPE WITH WALL CONTACTING PROBE - A spectroscope for detecting vulnerable plaque within a lumen defined by an intraluminal wall includes a probe through which an optical fiber extends. An coupler in optical communication with the fiber is configured to atraumatically contact the intraluminal wall. A light source provides light to the fiber for illuminating the wall and a detector coupled to the fiber receives light from within the wall. | 01-28-2010 |
20090281430 | CATHETER WITH SPINNING ULTRASOUND TRANSCEIVER BOARD - An apparatus for detecting vulnerable plaque in a blood vessel includes an intravascular probe, and a slip ring at a proximal end of the probe. The slip ring has a stationary portion and a spinning portion. An ultrasound transceiver board is mechanically coupled to the slip ring's spinning portion for communication with an ultrasound transducer, also within the probe. A transmission line extends between the ultrasound transducer and the ultrasound transceiver board. | 11-12-2009 |
20090270815 | Catheter Priming System - A catheter includes a longitudinally extending catheter body having proximal and distal ends. The catheter body defines a lumen extending longitudinally from a first port defined at the proximal end, through the body, to a second port defined at the distal end. The catheter includes a valve for controlling fluid flow through the second port. | 10-29-2009 |
20090253989 | System and Method for Intravascular Structural Analysis Compensation of Chemical Analysis Modality - A multimodal intravascular analysis uses a structural intravascular analysis modality to compensate for a chemical analysis modality. Examples of structural analysis are IVUS, OCT, including optical coherence domain Reflectometry (OCDR) and optical frequency domain imaging (OFDI), and/or sonar range finding. Examples of chemical or functional analysis are optical, NIR, Raman, fluorescence and spectroscopy, thermography and reflectometry. In one example, the structural analysis is used to characterize the environment structurally, such as catheter head-vessel wall distance. This information is then used to select from two or more algorithms which are depth specific (e.g. shallow vs. deep), to achieve improved accuracy in the chemical or functional analysis. | 10-08-2009 |
20090051923 | ARTERIAL PROBE FOR OCT - An apparatus and associated method for detecting vulnerable plaque within a lumen defined by an intraluminal wall is described. The apparatus includes a probe having a distal portion and a proximal portion. The apparatus includes an optical waveguide extending along the probe. The optical waveguide is configured to carry optical radiation between the distal and proximal portions, and has a distal end in communication with the intraluminal wall. The apparatus includes an interferometer coupled to the optical waveguide and configured to provide an interference signal for sub-surface imaging of the intraluminal wall, and a processing module configured to provide spectroscopic information from detected intensity of light collected from the intraluminal wall. | 02-26-2009 |
20090012407 | Spectroscopy of Deeply-Scattered Light - A spectroscope includes first and second beam redirectors in optical communication with first and second fibers respectively. The first and second beam redirectors are oriented to illuminate respective first and second areas. The second area is separated from the first area by a separation distance that exceeds the separation distance between the first and second beam redirectors. | 01-08-2009 |
20080221455 | NEAR-INFRARED SPECTROSCOPIC ANALYSIS OF BLOOD VESSEL WALLS - The invention relates to methods and devices for characterizing tissue in vivo, e.g., in walls of blood vessels, to determine whether the tissue is healthy or diseased, and include methods of displaying results with or without thresholds. | 09-11-2008 |