HOLOGIC, INC. Patent applications |
Patent application number | Title | Published |
20160120490 | Independently Rotatable Detector Plate for Medical Imaging Device - A real-time fluoroscopic imaging system includes a collimator and a detector which are rotationally movable independent of the support assembly, e.g., c-arm, to which they are mounted. Rotational movement of the collimator and the detector are coordinated such that the orientation of the detector with respect to the collimator does not change. The collimator may include a geared flange member to facilitate rotation, and may be a single molded piece formed of a plastic such as tungsten polymer material. The system may also include a plurality of interchangeable collimators characterized by different shapes. A display is provided to present an image to an operator, and image orientation logic displays a target anatomy in a selected orientation regardless of orientation of the target anatomy relative to the detector, and regardless of rotation of the detector. | 05-05-2016 |
20160106383 | TOMOSYNTHESIS WITH SHIFTING FOCAL SPOT AND OSCILLATIG COLLIMATOR BLADES - In a tomosynthesis system a static focal spot is moved in a direction opposite to and generally synchronized with the directional movement of an x-ray source and X-ray collimator blades are moved during each exposure in synchronization with the shifting of the static focal spot. The synchronized movement of the static focal spot, x-ray tube and collimator blades helps keep the effective focal spot fixed in space relative to the breast, detector or both during the entire duration of the exposure and keeps the x-ray field on the detector and breast static. The shifting collimator blades follow an oscillating pattern over the multiple x-ray exposures of a tomosynthesis scan. | 04-21-2016 |
20160051215 | SYSTEM AND METHOD FOR NAVIGATING A TOMOSYNTHESIS STACK INCLUDING AUTOMATIC FOCUSING - A system and method for reviewing a tomosynthesis image data set comprising volumetric image data of a breast, the method comprising, in one embodiment, causing an image or a series of images from the data set to be displayed on a display monitor operatively associated with the workstation; and selecting or indicating through a user interface comprising or operatively associated with the display monitor and workstation, an object or region of interest in a presently displayed image of the data set, thereby causing to be automatically displayed on the display monitor an image from the data set having a best focus measure of the user selected or indicated object or region of interest. | 02-25-2016 |
20160045214 | SURGICAL SYSTEM WITH EXPANDABLE SHIELD - A tissue removal system includes a morcellator having a cannula comprising a proximal end portion, a distal end portion, a sidewall, and at least one lumen extending between the proximal end portion and the distal end portion. A cutting blade is disposed within a lumen of the cannula. Also included is a tissue shield that has an expandable frame element and a shield element attached to the expandable frame element, wherein the tissue shield serves to isolate non-target tissues from at least the cutting blade of the system so that such tissues remain unaffected by a surgical procedure conducted with the system. | 02-18-2016 |
20160022230 | X-RAY SCATTER REDUCING DEVICE FOR USE WITH 2D AND 3D MAMMOGRAPHY - Systems and methods for reducing X-ray scatter during breast imaging, and more specifically during tomosynthesis imaging. In one embodiment, an anti-scatter grid having a plurality of septa may be configured to be positioned relative to an X-ray imaging device such that each septum of the plurality of septa extends along a direction substantially parallel to a coronal plane of a subject during imaging of the subject using the X-ray imaging device. The X-ray imaging device may be operable in a tomosynthesis mode for imaging of a breast of the subject and may include the anti-scatter grid disposed between a breast platform and the X-ray detector. The anti-scatter grid may be configured to move in a direction substantially parallel to a sagittal plane of the subject during tomosynthesis imaging. | 01-28-2016 |
20150366520 | Patient Support Pads for Use in Detecting Lymphedema Through X-Ray Scans - A system for detecting lymphedema comprising a dual energy x-ray absorptiometry system and one or more spacer pads disposed with a field of view of the dual energy x-ray absorptiometry system. The dual energy x-ray absorptiometry system comprising an x-ray source and a patient support platform, wherein the patient support platform is configured to receive a patient in a supine position with the x-ray source disposed above the patient support platform. The one or more spacer pads configured to be positioned body parts of the patient. | 12-24-2015 |
20150327826 | System and Method for Dual Energy and/or Contrast Enhanced Breast Imaging for Screening, Diagnosis and Biopsy - Systems and methods for x-ray imaging a patient's breast in combinations of dual-energy, single-energy, mammography and tomosynthesis modes that facilitate screening for and diagnosis of breast abnormalities, particularly breast abnormalities characterized by abnormal vascularity. | 11-19-2015 |
20150190101 | MAMMOGRAPHY SYSTEM AND METHOD EMPLOYING OFFSET COMPRESSION PADDLES, AUTOMATIC COLLIMATION, AND RETRACTABLE ANTI-SCATTER GRID - A mammographic imaging system is optimized for use with a single fixed size flat panel digital image receptor. It accommodates compression devices (paddles) of varying sizes, and positions them properly in a field of view of the image receptor. When a compression paddle with size smaller than the field of view of the image receptor is used the compression paddle can be shifted laterally in the direction parallel to the chest wall, so as to facilitate different views of different size breasts, and permit the image receptor to image as much of the desired tissue as possible. An automatic X-ray collimator restricts the X-ray illumination of the breast in accordance with the compression paddle size and location in the field of view. An anti-scatter grid, mounted inside the image receptor enclosure, just below the top cover of the enclosure, can be retracted out of the field of view of the image receptor for use in magnification imaging. | 07-09-2015 |
20150182181 | System and Method for Generating A 2D Image from a Tomosynthesis Data Set - A 2D mammogram image is synthesized from at least one of tomosynthesis projection images and/or the tomosynthesis reconstructed image data. In a simplest form, the mammogram may be synthesized by selecting one of the tomosynthesis projection images for display as a synthesized mammogram. Other methods of synthesizing a mammogram include re-projecting and filtering projection data and/or reconstructed data. The synthesized mammogram is advantageously displayed together with at least a portion of the reconstructed data to aid in review of the reconstructed data. The present invention thus provides a familiar image which may be used to facilitate review of a tomosynthesis data set. | 07-02-2015 |
20150174380 | CUFF-RESISTANT ANCHORING BALLOON FOR MEDICAL DEVICE - A medical device having an elongate support structure and an inflatable balloon including a first-end portion secured to the support structure at a first location, a second-end portion secured to the support structure at a second location distal to the first location, and a middle-body portion. The first-end portion has a wall thickness greater than a wall thickness of the middle-body portion; the balloon defines a sealed interior through which the support structure extends. The balloon being stretch-mounted to the support structure in tension relative to the support structure; the balloon is formed in a diamond-like configuration that transitions to a substantially spherical configuration when the balloon is inflated to a inflation pressure that is at least about ten percent greater than atmospheric pressure, such that when inflated to the inflation pressure and anchored in an anatomical body region, resists movement of the support structure relative to the balloon. | 06-25-2015 |
20150174372 | LOCKING DEVICE - A slidable locking device for fixing a position of a medical device, includes a housing having a passageway therethrough and an actuator coupled to the housing movable between a locked position and an unlocked position. The actuator includes at least two arms extending therefrom that are operatively coupled with at least two engaging members disposed within the housing, each engaging member having a slot configured to receive a respective arm of the actuator, the engaging members being biased towards the housing passageway, wherein the engaging members are disposed toward the housing passageway when the actuator is in the locked position, and the engaging members are disposed away from the housing passageway when the actuator is in the unlocked position. | 06-25-2015 |
20150160848 | IMAGE HANDLING AND DISPLAY IN X-RAY MAMMOGRAPHY AND TOMOSYNTHESIS - A method and system for acquiring, processing, storing, and displaying x-ray mammograms Mp tomosynthesis images Tr representative of breast slices, and x-ray tomosynthesis projection images Tp taken at different angles to a breast, where the Tr images are reconstructed from Tp images | 06-11-2015 |
20150146851 | BONE DENSITOMETER - A method includes moving a radiation source and a radiation detector along a scan path substantially transverse to a longitudinal axis of a patient. A beam of radiation is emitted from the radiation source. The beam of radiation is detected at the radiation detector. The detected beam is processed so as to form a first image of a first area of the patient along the scan path. | 05-28-2015 |
20150084631 | MRI SCANNER - Systems and methods for improving patient comfort and throughput of magnetic resonance imaging by providing at least one patient imaging area outside a bore of a magnet of a magnetic resonance imaging device. An embodiment of an apparatus for providing at least one patient imaging area outside the bore comprises a first shim disposed external to and spaced apart from a first opening of the bore to form a first patient imaging area between the first shim and the first opening, wherein the first shim is configured to direct a magnetic field of the magnet into the first patient imaging area to provide a first magnetic field in the first patient imaging area. Methods of magnetic resonance imaging outside the bore are also disclosed. | 03-26-2015 |
20150044708 | Methods for Detecting Oncofetal Fibronectin - Methods and products for the detection of oncofetal fibronectin indicating molecules in samples are provided. Methods for imaging of oncofetal fibronectin are provided. In some methods provided herein, the sample is treated with a reagent and/or contacted with a non-specific binder. Provided are methods for testing subjects to ascertain health and disease status and to assess the risk of developing a disease or condition. Methods for detecting the presence of oncofetal fibronectin indicating molecules by a variety of methods such as immunoassays and mass spectrometry also are provided. Methods and products for detection of oncofetal fibronectin for selection of concepti are | 02-12-2015 |
20150036910 | MEASURING INTRAMUSCULAR FAT - Dual-energy absorptiometry is used to estimate intramuscular adipose tissue metrics and display results, preferably as related to normative data. The process involves deriving x-ray measurements for respective pixel positions related to a two-dimensional projection image of a body slice containing intramuscular adipose tissue as well as subcutaneous adipose tissue, at least some of the measurements being dual-energy x-ray measurements, processing the measurements to derive estimates of metrics related to the intramuscular adipose tissue in the slice, and using the resulting estimates. Processing the measurements includes an algorithm which places boundaries of regions, e.g., a large region and a smaller region. The regions are combined in an equation that is highly correlated with intramuscular adipose tissue measured by quantitative computed tomography in order to estimate intramuscular adipose tissue. | 02-05-2015 |
20150031983 | MRI DISPLAY OUTPUT REFLECTING CONTRAST AGENT CONCENTRATION AS A FUNCTION OF TIME - A magnetic resonant imaging (MRI) review workstation includes a control processor, and a display integrated or otherwise operatively coupled with the control processor, wherein the control processor is configured to receive and analyze magnetic resonant imaging information pertaining to an imaged volume of tissue, and to cause to be displayed on the display output information that reflects or is otherwise indicative of an absorption rate of a contrast agent in the volume of tissue. | 01-29-2015 |
20140341337 | METHODS AND SYSTEMS FOR DYNAMICALLY MODIFYING ACQUISITION PARAMETER DURING IMAGE ACQUISITION - Systems and methods for automatically and dynamically modifying an image acquisition parameter for use in tomosynthesis breast imaging. A selected image acquisition parameter is modified in response to a measured characteristic of an imaged object such as a breast, and thus tailored to provide the highest quality image for the particular object. For example, image quality in a breast tomosynthesis system can be improved by dynamically varying motion and other acquisition parameters of the tomosynthesis system in response to physical characteristics of the breast to be imaged (determined during image acquisition), such as the breast thickness, density or composition. Dynamically varying acquisition or processing methods helps to customize the system for each particular patient, thereby improving image quality and identification and assessment of potential pathologies and abnormalities, and lower radiation dose, and thus a reduced the risk of long-term adverse health effects due to lifetime accumulated radiation dose. | 11-20-2014 |
20140321607 | UPRIGHT X-RAY BREAST IMAGING WITH A CT MODE, MULTIPLE TOMOSYNTHESIS MODES, AND A MAMMOGRAPHY MODE - A multi-mode system and method for imaging a patient's breast with x-rays in one or more of a CT mode, a narrow-angle tomosynthesis mode, a wide angle tomosynthesis mode, and a mammography mode, using essentially the same equipment, on one or more compressions or immobilizations of the breast. | 10-30-2014 |
20140314300 | SYSTEM AND METHOD FOR REVIEWING AND ANALYZING CYTOLOGICAL SPECIMENS - Systems and methods of use to facilitate classification of cytological specimens are discussed. The system acquires or imports image data of a cytological specimen. The imported image data may include, or the system may otherwise perform an image analysis to identify one or more objects of interest in a respective specimen image dataset, including feature attributes for the identified objects. The system analyzes the feature attributes by predetermined criteria and/or optionally with user inputted criteria. The system includes an analysis tool that assists the user in identifying cytologically abnormal objects, if present in a particular specimen, by manipulating and viewing images of objects selected as a function of feature attributes. More generally, the analysis tool aides the user to find, extract, and display abnormal objects from within a large dataset of images and facilitates navigation through large amounts of image data and enables the efficient classification of the entire specimen. | 10-23-2014 |
20140276234 | INTRAUTERINE MEASUREMENT DEVICE - Uterine sounds are provided including an insertion member having a distal end, a proximal end, and a lumen, wherein the insertion member is configured for insertion through an endocervical canal. A measurement member is provided having a distal end and a proximal end, the measurement member configured to move within the lumen of the insertion member, where the distal end can protrude from the distal end of the insertion member and is configured for insertion to approximately the fundus of a uterine cavity. An expansion member is also provided transitionable between an unexpanded and expanded state, wherein the unexpanded position is configured to pass an internal cervical os, and the expanded position is configured to prevent passage. Once the expansion member is positioned, the measurement member is positioned relative to the insertion member to establish a measurement of a depth of the uterine cavity. | 09-18-2014 |
20140257135 | SYSTEM FOR IMPROVED TISSUE HANDLING AND IN LINE ANALYSIS OF THE TISSUE - A system for analysis of biopsy samples includes a tissue sample transport mechanism linking a biopsy sample excision tool to a tissue sample holder disposed in a staging area of an analysis unit. The tissue sample is automatically transported from the excision tool to the specimen holder, where the tissue sample is analyzed in the staging area of the analysis unit. The transport mechanism may include tubing and a vacuum source. The tissue sample holder may be configured to slow or temporarily stop a tissue sample for individual analysis, or collect multiple tissue samples for analysis as a group. A tissue sample sorting mechanism may be employed that allows separation of specimens that can be correlated to the analysis. | 09-11-2014 |
20140255940 | MULTI-WELL PLATE AND METHOD OF USE - A biological sample well plate includes a plate member having a top surface and a plurality of wells therein, each well being defined by an opening in the plate member top surface and an inner well surface that slopes downwardly to a well bottom having an upwardly extending projection, such that each well bottom of the plurality of wells defines a circumferential trough. | 09-11-2014 |
20140232752 | MATCHING GEOMETRY GENERATION AND DISPLAY OF MAMMOGRAMS AND TOMOSYNTHESIS - A method and a system for using tomosynthesis projection images of a patient's breast to reconstruct slice tomosynthesis images such that anatomical structures that appear superimposed in a mammogram are at conforming locations in the reconstructed images. | 08-21-2014 |
20140222391 | System and Method for Generating Enhanced Density Distribution in a three Dimensional Model of a Structure for Use in Skeletal Assessment Using a Limited Number of Two Dimensional Views - A method of generating a density enhanced model of an object is described. The method includes generating a customized a model of an object using a pre-defined set of models in combination with at least one projection image of the object, where the customized model is formed of a plurality of volume elements including density information. A density map is generated by relating a synthesized projection image of the customized model to an actual projection image of the object. Gains from the density map are back-projected into the customized model to provide a density enhanced customized model of the object. Because the density map is calculated using information from the synthesized projection image in combination with actual projection images of the structure, it has been shown to provide spatial geometry and volumetric density results comparable to those of QCT but with reduced patient exposure, equipment cost and examination time. | 08-07-2014 |
20140216467 | FUNDUS BUMPER MECHANICAL REFERENCE FOR EASIER MECHANISM DEPLOYMENT - Intrauterine devices and methods for facilitating deployment thereof using a bumper are disclosed. In one embodiment, an intrauterine device comprises a structure including a first central support member and a deployment mechanism coupled to the first central support member. The intrauterine device further comprises a bumper positioned at a distal end of a second central support member and at a more distal position relative to a distal end of the structure so as to prevent the distal end of the structure from contacting the fundus of the uterus of a patient during deployment of the deployment mechanism. In another embodiment, the intrauterine device comprises a bumper coupled to the deployment mechanism and configured to move from a more distal to a more proximal position relative to a distal end of the structure. | 08-07-2014 |
20140204373 | System and Device for Non-Destructive Raman Analysis - A Raman microspectrometer system extends the optical reach and analysis range of an existing Raman microspectrometer to allow analysis and/or repair of an oversized sample. The Raman microspectrometer system includes an extender for extending the optical reach of the existing microspectrometer and a supplemental stage which extends the analysis range of the existing microspectrometer by providing travel capabilities for non-destructive analysis of an entire oversized sample. Such an arrangement decreases manufacturing costs associated with testing oversized samples such as mammography panels, enabling analysis and/or repair to be performed without destruction. | 07-24-2014 |
20140200591 | CERVICAL SEALING APPARATUS - Aspects and embodiments directed to cervical seals are disclosed. In one embodiment, a cervical seal having adjustable length comprises a first portion and a second portion, each configured to receive an elongated central member, a length of the cervical seal corresponding to a distance between the first portion and the second portion. The cervical seal further comprises a membrane coupled to the first portion and the second portion and extending along the length of the cervical seal, wherein the first portion is movable from a first position along the elongated central member to a second position along the elongated central member, so as to change the length of the cervical seal and the membrane is configured so that a radial profile of the membrane increases in response to increasing the length of the cervical seal, so as to provide a conformable cervical seal. | 07-17-2014 |
20140194777 | SWAB ASSEMBLY FOR SPECIMEN COLLECTION - A swab assembly for collecting a specimen from a patient includes an elongated shaft having a proximal end, a distal end, and a notch between its proximal and distal ends; a sheath having a proximal end, a distal end, and a lumen extending between its proximal and distal ends, wherein a portion of the elongated shaft is disposed within the sheath lumen, and the sheath is slidable relative to the elongated shaft; and a collection tip coupled to the distal end of the elongated shaft and configured for obtaining the specimen. The sheath is slidable between a first position in which the shaft notch is disposed within the sheath lumen and wherein the sheath protects the elongated shaft from breaking at the notch, and a second position in which the shaft notch is exposed out of the sheath lumen. | 07-10-2014 |
20140193848 | SAMPLE VIAL CAP AND SAMPLE VIAL FOR USE IN PREPARING CYTOLOGICAL SPECIMEN AND METHOD OF PREPARING CYTOLOGICAL SPECIMEN - A cap configured for use with a specimen container includes a cap body having a top surface defining an opening therethrough, a torque pattern disposed on the top surface of the cap body, and a pierceable and self-resealing membrane disposed across the opening, where, when the membrane is intact or resealed, the membrane forms a fluid-tight seal across the opening. | 07-10-2014 |
20140185902 | Estimating Risk Of Future Bone Fracture Utilizing Three-Dimensional Bone Density Model - A novel approach for analyzing a patient's body part of interest to assess bone strength and/or risk of future fracture includes obtaining a priori information regarding the body part of interest, performing X-ray absorptiometric scans of the patient's body part of interest and collecting X-ray absorptiometry data from the scans, constructing a three-dimensional model of the patient's body part of interest, by utilizing the a priori information along with the X-ray absorptiometric data, and performing measurements of various geometric parameters on the three-dimensional model for determining geometric and structural properties. | 07-03-2014 |
20140178976 | IMMUNOASSAY TEST STRIP FOR USE IN A DIAGNOSTIC SYSTEM - An immunoassay test strip includes a sample pad for receiving a liquid patient sample; a conjugate pad fluidly coupled to the sample pad, wherein the conjugate pad contains a substantially uniform application of conjugate reagent; a contact pad fluidly coupled to the conjugate pad; a porous or bibulous member, e.g., made from nitrocellulose, fluidly coupled to the contact pad which is capable or transporting a liquid sample along the test strip, wherein the porous or bibulous member serves as the solid support upon which immunoreactions occur, and an absorbent pad fluidly coupled to the porous or bibulous member, which serves to draw sample fluid introduced onto the sample pad through the respective conjugate pad, contact pad and porous or bibulous member. | 06-26-2014 |
20140154714 | Detection of Intraamniotic Infection - The present invention concerns the identification of biomarkers and groups or combinations of biomarkers that can be used for non-invasive diagnosis of intra-amniotic infection, and diagnostic assays using such biomarkers. | 06-05-2014 |
20140128883 | OPEN ARCHITECTURE IMAGING APPARATUS AND COIL SYSTEM FOR MAGNETIC RESONANCE IMAGING - This invention discloses a method and apparatus to deliver medical devices to targeted locations within human tissues using imaging data. The method enables the target location to be obtained from one imaging system, followed by the use of a second imaging system to verify the final position of the device. In particular, the invention discloses a method based on the initial identification of tissue targets using MR imaging, followed by the use of ultrasound imaging to verify and monitor accurate needle positioning. The invention can be used for acquiring biopsy samples to determine the grade and stage of cancer in various tissues including the brain, breast, abdomen, spine, liver, and kidney. The method is also useful for delivery of markers to a specific site to facilitate surgical removal of diseased tissue, or for the targeted delivery of applicators that destroy diseased tissues in-situ. | 05-08-2014 |
20140112563 | Breast Tomosynthesis with Display of Highlighted Suspected Calcifications - Systems and methods that facilitate the presentation and assessment of selected features in projection and/or reconstructed breast images, such as calcifications that meet selected criteria of size, shape, presence in selected slice images, distribution of pixels that could be indicative of calcification relative to other pixels or of other image features of clinical interest. | 04-24-2014 |
20140107404 | SYSTEMS, METHODS AND DEVICES FOR PERFORMING GYNECOLOGICAL PROCEDURES - Systems, methods, apparatus and devices for performing improved gynecologic and urologic procedures are disclosed. The system and devices provide simplified use and reduced risk of adverse events. Patient benefit is achieved through improved outcomes, reduced pain, especially peri-procedural pain, and reduced recovery times. The various embodiments enable procedures to be performed outside the hospital setting, such as in a doctor's office or clinic. | 04-17-2014 |
20140098935 | Mammography System and Method Employing Offset Compression Paddles, Automatic Collimation, and Retractable Anti-scatter Grid - A mammographic imaging system is optimized for use with a single fixed size flat panel digital image receptor. It accommodates compression devices (paddles) of varying sizes, and positions them properly in a field of view of the image receptor. When a compression paddle with size smaller than the field of view of the image receptor is used, the compression paddle can be shifted laterally in the direction parallel to the chest wall, so as to facilitate different views of different size breasts, and permit the image receptor to image as much of the desired tissue as possible. An automatic X-ray collimator restricts the X-ray illumination of the breast in accordance with the compression paddle size and location in the field of view. An anti-scatter grid, mounted inside the image receptor enclosure, just below the top cover of the enclosure, can be retracted out of the field of view of the image receptor for use in magnification imaging. | 04-10-2014 |
20140089837 | DISPLAYING AND NAVIGATING COMPUTER-AIDED DETECTION RESULTS ON A REVIEW WORKSTATION - Display and navigation for multiple computer-aided detection (CAD) detections is described. A medical image is displayed to a viewer, and a request is received to instantiate CAD-assisted viewing. A timewise presentation sequence for the CAD detections is automatically computed according to a predetermined sequencing criterion. For each CAD detection, an expanded presentation window is displayed for its associated location in the medical image, the expanded presentation windows being displayed according to the timewise presentation sequence. Also described is a navigational tool comprising a plot of an operating curve onto which a computed feature associated with the CAD algorithm can be mapped, the operating curve characterizing an application of the CAD algorithm to a reference database of mammographic cases having known diagnoses. The navigational tool further comprises a plurality of CAD pointer icons spatially distributed therealong according to mappings of the computed feature for the CAD detections onto the operating curve. | 03-27-2014 |
20140086471 | System and Method for Generating A 2D Image from a Tomosynthesis Data Set - A 2D mammogram image is synthesized from at least one of tomosynthesis projection images and/or the tomosynthesis reconstructed image data. In a simplest form, the mammogram may be synthesized by selecting one of the tomosynthesis projection images for display as a synthesized mammogram. Other methods of synthesizing a mammogram include re-projecting and filtering projection data and/or reconstructed data. The synthesized mammogram is advantageously displayed together with at least a portion of the reconstructed data to aid in review of the reconstructed data. The present invention thus provides a familiar image which may be used to facilitate review of a tomosynthesis data set. | 03-27-2014 |
20140073913 | BREAST BIOPSY AND NEEDLE LOCALIZATION USING TOMOSYNTHESIS SYSTEMS - Methods, devices, apparatuses and systems are disclosed for performing mammography, such as utilizing tomosynthesis in combination with breast biopsy. | 03-13-2014 |
20140058286 | Table for Performing Medical Procedures - The table for performing breast biopsies is characterized by features that enhance patient comfort and facilitate performance of the biopsy. An opening in the table allowing the breast to extend below the table top is formed in a removable insert. An area of the insert includes padding. An alternate insert having a different diameter opening may be selected based on patient breast size. Another insert having an asymmetrical opening may accommodate the patient's arm when it is desirable to position both the arm and breast of the patient below the table top. The table top is contoured such that symmetrical distal end sections are elevated relative to a central section to support the patient in multiple positions. A removable pad may be placed over the insert. An end portion for padding the hip of the patient is thicker than an end portion for padding the head/neck of the patient. | 02-27-2014 |
20140057259 | METHODS FOR ANALYSIS OF NUCLEIC ACID MOLECULES DURING AMPLIFICATION REACTIONS - The present invention provides systems, methods and kits for performing a detection assay (e.g., invasive cleavage assay) in combination with an amplification assay (e.g., PCR), where the detection assay employs enzyme footprint probes with relatively short (e.g., 6-12 bases) analyte-specific regions configured to provide a preferred footprint length of duplex for use with a particular nucleic acid modifying enzyme. In some embodiments, such assays are used for target quantification, and in other embodiments, such assays are used for genotyping. In certain embodiments, the use of such short probes allows for assays with increased dynamic range. | 02-27-2014 |
20140044325 | SYSTEM AND METHOD OF OVERLAYING IMAGES OF DIFFERENT MODALITIES - Systems and methods of overlaying a three-dimensional image of a tissue and an image of the tissue from an imaging transducer, having a field of view are disclosed. The method includes determining pixel dimensions of the field of view in the second co-ordinate space, scaling the three-dimensional image in the first co-ordinate space to match the pixel dimensions of the field of view in the second co-ordinate space, and displaying an overlaid image comprising the three-dimensional image and the field of view of the imaging transducer. | 02-13-2014 |
20140044231 | Integrated Multi-Mode Mammography/Tomosynthesis X-Ray System and Method - A system for multi-mode breast x-ray imaging which comprises a compression arm assembly for compressing and immobilizing a breast for x-ray imaging, an x-ray tube assembly, and an x-ray image receptor is provided. The system is configured for a plurality of imaging protocols and modes. | 02-13-2014 |
20140044230 | System and Method for Low Dose Tomosynthesis - A breast imaging system leverages the combined strengths of two-dimensional and three-dimensional imaging to provide a breast cancer screening with improved sensitivity, specificity and patient dosing. A tomosynthesis system supports the acquisition of three-dimensional images at a dosage lower than that used to acquire a two-dimensional image. The low-dose three-dimensional image may be used for mass detection, while the two-dimensional image may be used for calcification detection. Obtaining tomosynthesis data at low dose provides a number of advantages in addition to mass detection including the reduction in scan time and wear and tear on the x-ray tube. Such an arrangement provides a breast cancer screening system with high sensitivity and specificity and reduced patient dosing. | 02-13-2014 |
20140033126 | Displaying Computer-Aided Detection Information With Associated Breast Tomosynthesis Image Information - Methods, systems, and related computer program products for processing and displaying computer-aided detection (CAD) information associated with medical breast x-ray images, such as breast x-ray tomosynthesis volumes, are described. An interactive graphical user interface for displaying a tomosynthesis data volume is described that includes a display of a two-dimensional composited image having slabbed sub-images spatially localized to marked CAD findings. Also described is a graphical navigation tool for optimized CAD-assisted viewing of the data volume, comprising a plurality of CAD indicator icons running near and along a slice ruler, each CAD indicator icon spanning a contiguous segment of the slice ruler and corresponding in depthwise position and extent to a subset of image slices spanned by the associated CAD finding, each CAD indicator icon including at least one single-slice highlighting mark indicating a respective image slice containing viewable image information corresponding to the associated CAD finding. | 01-30-2014 |
20140024965 | LUMEN OCCLUSION DETECTION - Devices and methods are disclosed to detect or verify fallopian tube occlusion. Devices include an elongated body, a continuous open space extending between proximal and distal openings, a first pressure sensor or flow meter configured to measure a pressure or fluid flow within the continuous open space, at least one seal member protruding from the outer wall of the elongated body, and a second pressure sensor or flow meter configured to measure a pressure or flow meter within a space created by the at least one seal member. | 01-23-2014 |
20140024926 | OPEN ARCHITECTURE IMAGING APPARATUS AND COIL SYSTEM FOR MAGNETIC RESONANCE IMAGING - Apparatus and method for using radio frequency coil systems for magnetic resonance imaging within an open architecture apparatus is provided. The MRI coil system includes a support structure with an open architecture in which secondary support structures, compression systems and plates containing RF coil systems may be introduced. These structures and RF coils can be moved relative to the patient, or removed entirely from the system. In one embodiment the system consists of a tabletop coil system, while another embodiment consists of a dedicated stretcher design. | 01-23-2014 |
20140018607 | SYSTEM AND METHOD FOR IMAGE-GUIDED THERAPY PLANNING AND PROCEDURE - A method for generating a treatment plan for therapy comprising obtaining image data representing a tissue, determining a therapy dose map comprising dose values for a plurality of dose points based on the image data, forming a desired dose value vector comprising the dose values for the plurality of dose points, determining a one or more potential therapy locations based on the image data, determining a therapy dose map equation for each of the plurality of dose points based on the one or more potential therapy locations, forming a matrix based on the therapy dose map equations for the each dose points, determining an inverse of the matrix and determining the treatment plan by multiplying the desired dose value vector by the inverse of the matrix. | 01-16-2014 |
20140016737 | TOMOSYNTHESIS WITH SHIFTING FOCAL SPOT AND OSCILLATING COLLIMATOR BLADES - In a tomosynthesis system a static focal spot is moved in a direction opposite to and generally synchronized with the directional movement of an x-ray source and X-ray collimator blades are moved during each exposure in synchronization with the shifting of the static focal spot. The synchronized movement of the static focal spot, x-ray tube and collimator blades helps keep the effective focal spot fixed in space relative to the breast, detector or both during the entire duration of the exposure and keeps the x-ray field on the detector and breast static. The shifting collimator blades follow an oscillating pattern over the multiple x-ray exposures of a tomosynthesis scan. | 01-16-2014 |
20130312763 | Methods And Apparatus For Occlusion Of Body Lumens - The invention describes methods and apparatus for creating permanent occlusion of body lumens such as the fallopian tubes. The methods and apparatus use non-surgical approaches to deliver permanent implants which create acute occlusion of desired body lumens which resolve to permanent occlusions of the lumens. | 11-28-2013 |
20130308752 | Apparatus and Method for Detecting Lymphedema Using X-Ray Scans - A system for detecting lymphedema comprising a dual energy x-ray absorptiometry system and one or more spacer pads disposed within a field of view of the dual energy x-ray absorptiometry system. The dual energy x-ray absorptiometry system comprising an x-ray source and a patient support platform, wherein the patient support platform is configured to receive a patient in a supine position with the x-ray source disposed above the patient support platform. The one or more spacer pads configured to be positioned between body parts of the patient. | 11-21-2013 |
20130272494 | X-RAY MAMMOGRAPHY WITH TOMOSYNTHESIS - A method and system for producing tomosynthetic images of a patient's breast. An x-ray source that delivers x-rays through a breast immobilized and compressed between a compression paddle and a breast platform and form an image at a digital x-ray receptor panel. Multiple x-ray images are taken as the x-ray source and the receptor move relative to the immobilized breast. In one preferred embodiment, the x-ray source travels from −15° to +15°. The source can travel in an arc around the breast while the receptor travels linearly while remaining parallel and at the same distance from the breast platform. The sets of x-ray image data taken at different angles are combined to form tomosynthetic images that can be viewed in different formats, alone or as an adjunct to conventional mammograms. | 10-17-2013 |
20130251103 | METHOD FOR BREAST SCREENING IN FUSED MAMMOGRAPHY - A method for use in medical imaging of a patient including, with the patient immobilized with respect to an imaging reference frame, acquiring first digital imaging information including a first region of interest using a first imaging modality; processing the first digital imaging information to identify a feature for analysis; and using a second imaging modality to acquire targeted second imaging information for a second region of interest, the second region of interest corresponding to a subset of the first region of interest, wherein the second region of interest includes the feature for analysis. An apparatus for use in medical imaging comprising structure for immobilizing a patient with respect to an imaging reference frame; a first imaging system for acquiring first digital imaging information including a first region of interest using a first imaging modality; a processor processing the first digital imaging information using a diagnostic tool to identify a feature of interest; and a second imaging system for acquiring second imaging information using a second imaging modality, the second imaging information corresponding to a second region of interest including the feature for analysis. | 09-26-2013 |
20130239975 | IMPLANT DELIVERY DEVICE - Devices and methods are disclosed for the delivery of a compressible implant into a bodily lumen. The delivery device includes an enlarged section that is configured to house the implant during delivery thereof into a patient. In certain embodiments, the implant is kept within the delivery device in a substantially uncompressed configuration prior to the delivery thereof. | 09-19-2013 |
20130231585 | SYSTEM FOR IMPROVED TISSUE-HANDLING AND IN LINE ANALYSIS OF THE TISSUE - A system for analysis of biopsy samples includes a tissue sample transport mechanism linking a biopsy sample excision tool to a tissue sample holder disposed in a staging area of an analysis unit. The tissue sample is automatically transported from the excision tool to the specimen holder, where the tissue sample is analyzed in the staging area of the analysis unit. The transport mechanism may include tubing and a vacuum source. The tissue sample holder may be configured to slow or temporarily stop a tissue sample for individual analysis, or collect multiple tissue samples for analysis as a group. A tissue sample sorting mechanism may be employed that allows separation of specimens that can be correlated to the analysis. | 09-05-2013 |
20130223591 | FULL FIELD MAMMOGRAPHY WITH TISSUE EXPOSURE CONTROL, TOMOSYNTHESIS, AND DYNAMIC FIELD OF VIEW PROCESSING - A mammography system using a tissue exposure control relying on estimates of the thickness of the compressed and immobilized breast and of breast density to automatically derive one or more technic factors. The system further uses a tomosynthesis arrangement that maintains the focus of an anti-scatter grid on the x-ray source and also maintains the field of view of the x-ray receptor. Finally, the system finds an outline that forms a reduced field of view that still encompasses the breast in the image, and uses for further processing, transmission or archival storage the data within said reduced field of view. | 08-29-2013 |
20130178738 | System and Method for Tissue Ablation in a Body Cavity - A tissue ablation system and method of forming same includes an ablation device having a substrate with an outer surface and energy transport elements coupled to the outer surface. The substrate is configured to have a shape that approximates an interior shape of a uterus. The system and method further including an energy source electrically coupled to the energy transport elements and at least one ultrasonic transducer positioned in a lateral region of the uterus. | 07-11-2013 |
20130171672 | Methods for Detecting Oncofetal Fibronectin - Methods and products for the detection of oncofetal fibronectin indicating molecules in samples are provided. Methods for imaging of oncofetal fibronectin are provided. In some methods provided herein, the sample is treated with a reagent and/or contacted with a non-specific binder. Provided are methods for testing subjects to ascertain health and disease status and to assess the risk of developing a disease or condition. Methods for detecting the presence of oncofetal fibronectin indicating molecules by a variety of methods such as immunoassays and mass spectrometry also are provided. Methods and products for detection of oncofetal fibronectin for selection of concepti are | 07-04-2013 |
20130129039 | X-RAY MAMMOGRAPHY AND/OR BREAST TOMOSYNTHESIS USING A COMPRESSION PADDLE WITH AN INFLATABLE JACKET ENHANCING IMAGING AND IMPROVING PATIENT COMFORT - A system and method using an inflatable jacket over the compression paddle of a mammography and/or tomosynthesis system to enhance imaging and improve patient comfort in x-ray breast imaging. | 05-23-2013 |
20130072816 | Breast Biopsy Lateral Arm System - A biopsy device includes a lateral member; a gun mount configured to support a biopsy gun, the gun mount being connected to the lateral member and movable along a first axis with respect to the lateral member, and a sensor which detects a position of the gun mount along the first axis with respect to the lateral member and generates positional data which is provided to an interface module. The gun mount can also be reconfigured in orientations which are offset in a dimension which is orthogonal to the first axis, orientations rotationally offset about the first axis or an axis parallel to the first axis. The lateral member can be in right hand and left hand orientations. Various sensors detect these reconfigurations and provide corresponding data to the interface module for additional calculations and display. | 03-21-2013 |
20130058462 | INDEPENDENTLY ROTATABLE DETECTOR PLATE FOR MEDICAL IMAGING DEVICE - A real-time fluoroscopic imaging system includes a collimator and a detector which are rotationally movable independent of the support assembly, e.g., c-arm, to which they are mounted. Rotational movement of the collimator and the detector are coordinated such that the orientation of the detector with respect to the collimator does not change. The collimator may include a geared flange member to facilitate rotation, and may be a single molded piece formed of a plastic such as tungsten polymer material. The system may also include a plurality of interchangeable collimators characterized by different shapes. A display is provided to present an image to an operator, and image orientation logic displays a target anatomy in a selected orientation regardless of orientation of the target anatomy relative to the detector, and regardless of rotation of the detector. | 03-07-2013 |
20130053684 | OPEN ARCHITECTURE TABLETOP PATIENT SUPPORT AND COIL SYSTEM - An assembly for magnetic resonance imaging (MRI) of a patient and a method of magnetic resonance imaging (MRI) of a patient using different MRI scanners is disclosed. In one example, the assembly includes a plurality of RF coils, wherein the RF coils are configured to be positioned adjacent to an anatomy of interest, a patient support structure configured to support of the patient, a base removably coupled to the patient support structure, the base and the patient support being configured for receipt in the bore of an MRI scanner, and an interface coupled to the plurality of RF coils and to the MRI scanner and configured to connect the plurality of RF coils and the MRI scanner and to selectively control a first RF coil and a second RF coil included in the plurality of RF coils. | 02-28-2013 |
20130046316 | TISSUE REMOVAL SYSTEM - A tissue removal device includes an outer tubular member coupled to a housing and a having a tissue resection window, an inner tubular member slidably disposed within the outer tubular member, a tissue trap having a sealed interior in fluid communication with a vacuum chamber, an open proximal end of the inner tubular member being disposed within the tissue trap interior, and an actuator moveably coupled to the housing and operatively connected to a movable piston in the vacuum chamber, such that movement of the actuator relative to the housing generates a vacuum in the tissue trap. | 02-21-2013 |
20130028374 | IMAGE HANDLING AND DISPLAY IN X-RAY MAMMOGRAPHY AND TOMOSYNTHESIS - A method and system for acquiring, processing, storing, and displaying x-ray mammograms Mp tomosynthesis images Tr representative of breast slices, and x-ray tomosynthesis projection images Tp taken at different angles to a breast, where the Tr images are reconstructed from Tp images | 01-31-2013 |
20120328176 | MULTI-MODE TOMOSYNTHESIS/MAMMOGRAPHY GAIN CALIBRATION AND IMAGE CORRECTION USING GAIN MAP INFORMATION FROM SELECTED PROJECTION ANGLES - A multi-mode tomosynthesis/mammography system and method in which a mammography gain map is used to gain correct mammographic images of a patient's breast but enhanced gain maps for respective projection angled are used to correct tomosynthesis images acquired with the same system. | 12-27-2012 |
20120288057 | DEDICATED BREAST RADIATION IMAGING/THERAPY SYSTEM - System, apparatus and methods specialized for breast and related tissue radiation therapy and imaging of a prone patient but also usable for supine patient if desired or needed. A special treatment radiation source such as a LINAC unit generates radiation of types and energy ranges specifically matched to breast tissue. Any one or more of several imaging technologies may be used to localize the tissue to be irradiated and to generate information for therapy planning, adjustment, and verification. | 11-15-2012 |
20120268737 | System and Device for Non-Destructive Raman Analysis - An improved Raman microspectrometer system extends the optical reach and analysis range of an existing Raman microspectrometer to allow analysis and/or repair of an oversized sample. The improved Raman microspectrometer system includes an extender for extending the optical reach of the existing microspectrometer and a supplemental stage which extends the analysis range of the existing microspectrometer by providing travel capabilities for non-destructive analysis of an entire oversized sample. Such an arrangement decreases manufacturing costs associated with testing oversized samples such as mammography panels, enabling analysis and/or repair to be performed without destruction. | 10-25-2012 |
20120266892 | TETHERED IMPLANT AND RELATED METHOD OF USE - An implant configured for insertion and placement within a fallopian tube of a female during a sterilization procedure. The implant includes an implant body having proximal and distal ends and a tether. The tether is attached to the implant body and extends a distance away from the implant body. The tether may be bioabsorbable and/or detachably coupled to the implant body so that the tether can be separated from the implant body without dislodging the implant body from the fallopian tube. | 10-25-2012 |
20120250969 | Integrated Breast X-Ray and Molecular Imaging System and Method - An integrated tomosynthesis/molecular breast imaging device having improved sensitivity includes tomosynthesis imaging components and molecular breast imaging components. The imaging components may be used individually or in combination to provide a system with improved sensitivity and specificity. Molecular imaging components may be smoothly advanced or withdrawn depending upon the desired imaging mode. The system supports both PET and SPECT imaging and enables SPECT collimation to be modified in accordance with image capture requirements. | 10-04-2012 |
20120243755 | METHOD FOR AUTOMATICALLY SEEDING PREVIOUSLY-CLASSIFIED IMAGES AMONG IMAGES OF OBJECTS OF INTEREST FROM A SPECIMEN - A computer-assisted method of classifying cytological samples, includes using a processor to analyze images of cytological samples and identify cytological objects of interest within the sample images, wherein the processor (i) displays images of identified cytological objects of interest from the sample images to a reviewer, (ii) accesses a database of images of previously classified cytological objects, and (iii) displays to the reviewer, interspersed with the displayed images of the identified objects of interest from the sample images, one or more images obtained from the database of images of previously-classified objects. | 09-27-2012 |
20120238870 | SYSTEM AND METHOD FOR DUAL ENERGY AND/OR CONTRAST ENHANCED BREAST IMAGING FOR SCREENING, DIAGNOSIS AND BIOPSY - Systems and methods for x-ray imaging a patient's breast in combinations of dual-energy, single-energy, mammography and tomosynthesis modes that facilitate screening for and diagnosis of breast abnormalities, particularly breast abnormalities characterized by abnormal vascularity. | 09-20-2012 |
20120219111 | INTEGRATED MULTI-MODE MAMMOGRAPHY/TOMOSYNTHESIS X-RAY SYSTEM AND METHOD - A system for multi-mode breast x-ray imaging which comprises a compression arm assembly for compressing and immobilizing a breast for x-ray imaging, an x-ray tube assembly, and an x-ray image receptor is provided. The system is configured for a plurality of imaging protocols and modes. | 08-30-2012 |
20120216815 | CONSTANT RATE DELIVERY DEVICE - Medical devices and related methods are disclosed for delivering an implant into the body of a patient. The devices include a damping assembly having an internal chamber with a varying inner diameter, and a piston slideably disposed therein. The piston is operably connected with a catheter portion such that movement of the piston is associated with concurrent movement of the catheter for implant delivery. The varying inner diameter of the damping assembly results in a decrease in damping force during implant delivery, thus providing a substantially constant velocity of implant delivery. | 08-30-2012 |
20120214227 | APPARATUS FOR PREPARING CYTOLOGICAL SPECIMENS - A handheld apparatus for preparing a specimen slide includes a handle, a filter holder assembly coupled to and extending from the handle; and a slide holder assembly coupled to and extending from the handle spaced apart from the filter holder assembly, wherein the slide holder assembly comprises a plurality of positioning members movably coupled to one another, and a slide holder movably coupled to one of the positioning members to allow a slide mounted on the slide holder to make rolling contact with an outward facing surface of a filter mounted on the filter holder assembly. | 08-23-2012 |
20120210272 | Displaying And Navigating Computer-Aided Detection Results On A Review Workstation - Display and navigation for multiple computer-aided detection (CAD) detections is described. A medical image is displayed to a viewer, and a request is received to instantiate CAD-assisted viewing. A timewise presentation sequence for the CAD detections is automatically computed according to a predetermined sequencing criterion. For each CAD detection, an expanded presentation window is displayed for its associated location in the medical image, the expanded presentation windows being displayed according to the timewise presentation sequence. Also described is a navigational tool comprising a plot of an operating curve onto which a computed feature associated with the CAD algorithm can be mapped, the operating curve characterizing an application of the CAD algorithm to a reference database of mammographic cases having known diagnoses. The navigational tool further comprises a plurality of CAD pointer icons spatially distributed therealong according to mappings of the computed feature for the CAD detections onto the operating curve. | 08-16-2012 |
20120203095 | Systems and Methods for Trans-Orifice and Transperineal Intervention - An intervention apparatus is described having a probe with an orifice insertion portion, the insertion portion being configured for insertion into an orifice of a patient. The apparatus also having an intervention tool securement and adjustment mechanism removably attached to the probe. The probe providing support to hold the mechanism in a position relative to the patient, and the adjustment mechanism providing adjustment of an entry point and an angle of entry for an intervention tool to the patient. In embodiments, magnetic resonance imaging, trans-orifice intervention and transperineal intervention are described. Methods for imaging and/or intervention are also described. | 08-09-2012 |
20120201444 | Reducing False Positives In Computer-Aided Detection - Methods, systems, and related computer program products for computer-aided detection (CAD) of anatomical abnormalities in digital (or digitized) x-ray mammograms are described. The inventive techniques are based on using a foundational CAD processing algorithm that is characterized by at least one of non-shift-invariance, non-rotational-invariance, and non-inversional-invariance. According to one preferred embodiment, a first x-ray mammogram image of a breast is received, and at least one altered version thereof is generated that differs therefrom by at least one of image shift, image rotation, and image inversion. The first x-ray mammogram image and each of the at least one altered versions thereof are individually processed using the foundational CAD algorithm to generate a respective plurality of individual CAD detection sets. The plurality of CAD detection sets are then compared to generate an overall CAD detection set. | 08-09-2012 |
20120195484 | MATCHING GEOMETRY GENERATION AND DISPLAY OF MAMMOGRAMS AND TOMOSYNTHESIS IMAGES - A method and a system for using tomosynthesis projection images of a patient's breast to reconstruct slice tomosynthesis images such that anatomical structures that appear superimposed in a mammogram are at conforming locations in the reconstructed images. | 08-02-2012 |
20120172889 | TISSUE REMOVAL SYSTEM - A tissue removal system includes an inner tubular member configured to rotate and oscillate axially relative to an outer tubular member, and a reversible motor comprising a rotatable output shaft operatively coupled to the inner tubular member. A proximal end of the inner tubular member is disposed within, and configured to rotate and oscillate axially relative to, a housing. A first control switch disposed within the housing is actuated when the inner tubular member is in a distal position relative to the housing, and a second control switch disposed external to the housing is actuated by a user. The system further includes motor control circuitry configured such that when the second control switch is actuated, actuation of the first control switch causes the motor output shaft to change direction, and when the second control switch is not actuated, actuation of the first control switch causes the motor to turn off. | 07-05-2012 |
20120172888 | HYSTEROSCOPIC TISSUE REMOVAL SYSTEM WITH IMPROVED FLUID MANAGEMENT AND/OR MONITORING CAPABILITIES - A hysteroscopic tissue removal system having improved fluid management and/or monitoring capabilities. According to one embodiment, the system includes a hysteroscope and a tissue removal device, the tissue removal device being selectively operable and being removably mounted in an operating channel of the hysteroscope. The system also includes a fluid source and a fluid pump, the fluid pump being coupled to the fluid source and to a fluid input channel of the hysteroscope so as to pump fluid from the fluid source to the fluid input channel, the fluid pump being selectively operable. The system further includes a selectively operable switch, coupled to both the tissue removal device and the fluid pump, for actuating both the tissue removal device and the pump. If desired, a delay mechanism may be interposed between the switch and the tissue removal device to delay operation of the tissue removal device relative to the pump. | 07-05-2012 |
20120172704 | Open Architecture Imaging Apparatus and Coil System for Magnetic Resonance Imaging - Apparatus and method for using radio frequency coil systems for magnetic resonance imaging within an open architecture apparatus is provided. The MRI coil system includes a support structure with an open architecture in which secondary support structures, compression systems and plates containing RF coil systems may be introduced. These structures and RF coils can be moved relative to the patient, or removed entirely from the system. In one embodiment the system consists of a tabletop coil system, while another embodiment consists of a dedicated stretcher design. | 07-05-2012 |
20120133601 | USER INTERFACE FOR MEDICAL IMAGE REVIEW WORKSTATION - Methods, systems and computer program products for controlling display of different types of medical images and providing touchscreen interfaces for display on a mobile communication device and associated with different image types, e.g., different imaging modalities or different view modes. Detection of a multi-finger tap on the screen of the mobile communication device while viewing a first touchscreen interface for an image type invokes a second or auxiliary touchscreen interface for that image type having a subset of interface elements of the first touchscreen interface. | 05-31-2012 |
20120133600 | USER INTERFACE FOR MEDICAL IMAGE REVIEW WORKSTATION - Methods, systems and computer program products for controlling display of different types of medical images and providing touchscreen interfaces for display on a mobile communication device and associated with different image types, e.g., different imaging modalities or different view modes. Detection of a multi-finger tap on the screen of the mobile communication device while viewing a first touchscreen interface for an image type invokes a second or auxiliary touchscreen interface for that image type having a subset of interface elements of the first touchscreen interface. | 05-31-2012 |
20120130272 | LUMEN OCCLUSION DETECTION - Devices and methods are disclosed to detect or verify fallopian tube occlusion. Devices include an elongated body a continuous open space extending between proximal and distal openings, a first pressure sensor or flow meter configured to measure a pressure or fluid flow within the continuous open space, at least one seal member protruding from the outer wall of the elongated body, and a second pressure sensor or flow meter configured to measure a pressure or flow meter within a space created by the at least one seal member. | 05-24-2012 |
20120121155 | BREAST TOMOSYNTHESIS WITH DISPLAY OF HIGHLIGHTED SUSPECTED CALCIFICATIONS - Systems and methods that facilitate the presentation and assessment of selected features in projection and/or reconstructed breast images, such as calcifications that meet selected criteria of size, shape, presence in selected slice images, distribution of pixels that could be indicative of calcification relative to other pixels or of other image features of clinical interest. | 05-17-2012 |
20120114095 | Upright x-ray breast imaging with a CT mode, multiple tomosynthesis modes, and a mammography mode - A multi-mode system and method for imaging a patient's breast with x-rays in one or more of a CT mode, a narrow-angle tomosynthesis mode, a wide angle tomosynthesis mode, and a mammography mode, using essentially the same equipment, on one or more compressions or immobilizations of the breast. | 05-10-2012 |
20120111336 | IMPLANT DELIVERY DEVICE WITH EXPANDING TIP - Devices and methods are disclosed for the delivery of an implant into small bodily spaces. The delivery devices include an expandable portion configured for placement within such bodily spaces and subsequent expansion to facilitate the delivery of the implant. | 05-10-2012 |
20120082598 | Immunoassay Test Strip For Use in a Diagnostic System - An immunoassay test strip includes a sample pad for receiving a liquid patient sample; a conjugate pad fluidly coupled to the sample pad, wherein the conjugate pad contains a substantially uniform application of conjugate reagent; a contact pad fluidly coupled to the conjugate pad; a porous or bibulous member, e.g., made from nitrocellulose, fluidly coupled to the contact pad which is capable or transporting a liquid sample along the test strip, wherein the porous or bibulous member serves as the solid support upon which immunoreactions occur, and an absorbent pad fluidly coupled to the porous or bibulous member, which serves to draw sample fluid introduced onto the sample pad through the respective conjugate pad, contact pad and porous or bibulous member. | 04-05-2012 |
20120067352 | METHODS, SYSTEMS AND DEVICES FOR PERFORMING GYNECOLOGICAL PROCEDURES - Methods, systems and devices for performing gynecological procedures. According to one embodiment, there is provided a device for occluding a fallopian tube, the device including an outer member and an inner member. The outer member may be a hollow, frusto-conical structure shaped to include an open proximal end, an open distal end, and a side wall. The outer member may be self-expandable such that the distal end is biased radially outwardly. In addition, the side wall may have a porous structure to permit the ingrowth of tissue therethrough. Tines may be provided on the outer surface of the side wall to promote the anchoring of the outer member in a fallopian tube. The inner member, which may be structured to induce scarring, may comprise an elongated fibrous body fixed at its proximal end to the proximal end of the outer member. A bore may extend distally from the proximal end of the inner member to receive a delivery rod. The inner member, which may have pores or interstices to permit the ingrowth of tissue thereinto, is coated or impregnated with a sclerosing agent. | 03-22-2012 |
20120063567 | METHODS AND SYSTEMS FOR DETECTING POSSIBLE ERROR IN PATIENT POSITION - Systems and methods for automatically and dynamically modifying an image acquisition parameter for use in tomosynthesis breast imaging. A selected image acquisition parameter is modified in response to a measured characteristic of an imaged object such as a breast, and thus tailored to provide the highest quality image for the particular object. For example, image quality in a breast tomosynthesis system can be improved by dynamically varying motion and other acquisition parameters of the tomosynthesis system in response to physical characteristics of the breast to be imaged (determined during image acquisition), such as the breast thickness, density or composition. Dynamically varying acquisition or processing methods helps to customize the system for each particular patient, thereby improving image quality and identification and assessment of potential pathologies and abnormalities, and lower radiation dose, and thus a reduced the risk of long-term adverse health effects due to lifetime accumulated radiation dose. | 03-15-2012 |
20120063566 | METHODS AND SYSTEMS FOR DYNAMICALLY MODIFYING ACQUISITION PARAMETER DURING IMAGE ACQUISITION - Systems and methods for automatically and dynamically modifying an image acquisition parameter for use in tomosynthesis breast imaging. A selected image acquisition parameter is modified in response to a measured characteristic of an imaged object such as a breast, and thus tailored to provide the highest quality image for the particular object. For example, image quality in a breast tomosynthesis system can be improved by dynamically varying motion and other acquisition parameters of the tomosynthesis system in response to physical characteristics of the breast to be imaged (determined during image acquisition), such as the breast thickness, density or composition. Dynamically varying acquisition or processing methods helps to customize the system for each particular patient, thereby improving image quality and identification and assessment of potential pathologies and abnormalities, and lower radiation dose, and thus a reduced the risk of long-term adverse health effects due to lifetime accumulated radiation dose. | 03-15-2012 |
20120039437 | MULTI-MODE TOMOSYNTHESIS/MAMMOGRAPHY GAIN CALIBRATION AND IMAGE CORRECTION USING GAIN MAP INFORMATION FROM SELECTED PROJECTION ANGLES - A multi-mode tomosynthesis/mammography system and method in which a mammography gain map is used to gain correct mammographic images of a patient's breast but enhanced gain maps for respective projection angled are used to correct tomosynthesis images acquired with the same system. | 02-16-2012 |
20120020456 | MAMMOGRAPHY SYSTEM AND METHOD EMPLOYING OFFSET COMPRESSION PADDLES AUTOMATIC COLLIMATION AND RETRACTABLE ANTI-SCATTER GRID - A mammographic imaging system is optimized for use with a single fixed size flat panel digital image receptor. It accommodates compression devices (paddles) of varying sizes, and positions them properly in the field of view of the image receptor. When a compression paddle with size smaller than the field of view of the image receptor is used, the compression paddle can be shifted laterally in the direction parallel to the chest wall, so as to facilitate different views of different size breasts, and permit the image receptor to image as much of the desired tissue as possible. An automatic x-ray collimator restricts the x-ray illumination of the breast in accordance with compression paddle size and location in the field of view. An anti-scatter grid, mounted inside the image receptor enclosure, just below the top cover of the enclosure, can be retracted out of the field of view of the image receptor for use in magnification imaging. | 01-26-2012 |
20120010464 | ACCESS SYSTEM WITH REMOVABLE OUTFLOW CHANNEL - A surgical access device can comprise a working channel providing a first lumen having an axial opening for insertion of a surgical instrument having an outflow channel, the first lumen having a fluid inlet for allowing fluid flow through the working channel and into the body, wherein fluid flows out of the body through the outflow channel of the surgical instrument; and a optical channel providing a second lumen for a visualization element and a light source, wherein the working channel comprises a larger cross-sectional area than the cross-sectional area of the optical channel. The surgical access device can further comprise a seal apparatus coupled to the working channel and configured to receive the surgical instrument, the seal apparatus comprising a first seal portion and a second seal portion, the first seal portion configured to close the fluid path into the seal apparatus, and the second seal portion configured to form a seal with the surgical instrument. | 01-12-2012 |
20110276070 | RADIOPAQUE IMPLANT - Implants for placement in the fallopian tube are provided that comprise radiopaque material. Implants include an inner core of silicone, a radiopaque material, an outer porous portion surrounding the inner core, and, optionally, a sound-reflecting air pocket. The implant may be detected in a fluoroscopic image and/or via ultrasound after placement of the implant in the fallopian tube. | 11-10-2011 |
20110237927 | DEDICATED BREAST RADIATION IMAGING/THERAPY SYSTEM - System, apparatus and methods specialized for breast and related tissue radiation therapy and imaging of a prone patient but also usable for supine patient if desired or needed. A special treatment radiation source such as a LINAC unit generates radiation of types and energy ranges specifically matched to breast tissue. Any one or more of several imaging technologies may be used to localize the tissue to be irradiated and to generate information for therapy planning, adjustment, and verification. | 09-29-2011 |
20110216879 | Full Field Mammography With Tissue Exposure Control, Tomosynthesis, And Dynamic Field Of View Processing - A mammography system using a tissue exposure control relying on estimates of the thickness of the compressed and immobilized breast and of breast density to automatically derive one or more technic factors. The system further uses a tomosynthesis arrangement that maintains the focus of an anti-scatter grid on the x-ray source and also maintains the field of view of the x-ray receptor. Finally, the system finds an outline that forms a reduced field of view that still encompasses the breast in the image, and uses for further processing, transmission or archival storage the data within said reduced field of view. | 09-08-2011 |
20110194740 | Displaying Computer-Aided Detection Results Associated With A Medical Image Volume - Methods, systems, and related computer program products for processing and displaying computer-aided detection (CAD) results in conjunction with breast x-ray tomosynthesis data are described. For one preferred embodiment, as a user pages through a notional stack of tomosynthesis reconstructed slice images (Tr images), including a detection-containing Tr image on which a CAD marker is to be displayed at an identified coordinate location, one or more CAD proximity markers is displayed at that coordinate location on one or more neighboring Tr images. While not themselves indicative of CAD findings on their respective Tr images, the CAD proximity markers encourage user attention toward the coordinate location of the CAD detection marker of the detection-containing Tr image. Preferably, the CAD proximity markers are of noticeably different size from each other and from the CAD detection marker to promote their perception in the peripheral vision of the user during the paging process. | 08-11-2011 |
20110194157 | User Selectable and User Definable Scanning Protocols In Mammographic Film Scanning System With Stack Film Feeder - A system and method for processing mammographic data are described. The system includes a user input/output system adapted and configured to receive from a user a user-defined scanning protocol that identifies the laterality and view type for each mammographic film in a film case to be scanned. A storage system stores the user-defined scanning protocol for subsequent use in scanning film cases. A scanning system scans film cases and generates digitized versions of each mammographic film. A processor then assigns laterality and view types to the digitized versions of the mammographic film according to the user-defined scanning protocol. The system also receives user alterations to stored scanning protocols. The system can also re-assign a case scanned according to one scanning protocol to another scanning protocol in response to a user's instruction to do so. The system processes the digitized versions according to at least one computer aided detection (CAD) algorithm for detecting anatomical abnormalities therein. | 08-11-2011 |
20110146692 | Implant Delivery Device - Devices and methods are disclosed for the delivery of a compressible implant into a bodily lumen. The delivery device includes an enlarged section that is configured to house the implant during delivery thereof into a patient. In certain embodiments, the implant is kept within the delivery device in a substantially uncompressed configuration prior to the delivery thereof. | 06-23-2011 |
20110135185 | IMAGE HANDLING AND DISPLAY IN X-RAY MAMMOGRAPHY AND TOMOSYNTHESIS - A method and system for acquiring, processing, storing, and displaying x-ray mammograms Mp tomosynthesis images Tr representative of breast slices, and x-ray tomosynthesis projection images Tp taken at different angles to a breast, where the Tr images are reconstructed from Tp images | 06-09-2011 |
20110128289 | Facilitating Temporal Comparison of Medical Images - Methods, systems, and computer program products for facilitating temporal comparison of medical images is provided, with one exemplary application being for breast mammograms. In one embodiment, prior and subsequent mammographic images of a breast acquired using at least partially different mammogram acquisition systems are displayed for simultaneous viewing on a same mammogram display at an identical tissue distance per unit display distance without requiring a scale-adjusting viewer input. Also described are other embodiments for optimally scaling, windowing and/or otherwise advantageously processing and/or displaying prior and subsequent mammographic image sets in manners that facilitate temporal comparison therebetween. | 06-02-2011 |
20110110576 | Selective Display Of Computer-Aided Detection Findings With Associated Breast X-Ray Mammogram and/or Tomosynthesis Image Information - Methods, systems, and related computer program products for processing and displaying computer-aided detection (CAD) information associated with medical breast x-ray images, such as breast x-ray tomosynthesis volumes and conventional x-ray mammograms, are described. For one preferred embodiment, CAD findings for several cases (or several individual data volumes) are selectively designated for marking such that a predetermined number of CAD findings per case (or per data volume) are marked for display across all of the cases (or data volumes). In another preferred embodiment, localized breast fibroglandular tissue density information is used together with certainty-of-finding information as a basis for selecting which candidate CAD findings to designate as marked CAD findings, with increased certainty-of-finding being required to mark CAD findings in regions of higher fibroglandular tissue density. In another preferred embodiment, CAD findings located within regions of excessively dense fibroglandular tissue are withheld altogether, and associated warnings are displayed. | 05-12-2011 |
20110109650 | Displaying Computer-Aided Detection Information With Associated Breast Tomosynthesis Image Information - Methods, systems, and related computer program products for processing and displaying computer-aided detection (CAD) information associated with medical breast x-ray images, such as breast x-ray tomosynthesis volumes, are described. An interactive graphical user interface for displaying a tomosynthesis data volume is described that includes a display of a two-dimensional composited image having slabbed sub-images spatially localized to marked CAD findings. Also described is a graphical navigation tool for optimized CAD-assisted viewing of the data volume, comprising a plurality of CAD indicator icons running near and along a slice ruler, each CAD indicator icon spanning a contiguous segment of the slice ruler and corresponding in depthwise position and extent to a subset of image slices spanned by the associated CAD finding, each CAD indicator icon including at least one single-slice highlighting mark indicating a respective image slice containing viewable image information corresponding to the associated CAD finding. | 05-12-2011 |
20110103675 | Integrating Auxiliary Detection And Voting Algorithms Into Clinical CAD Workflow - Methods, systems, and related computer program products for computer-aided detection (CAD) of anatomical abnormalities in medical images are described. A preexisting CAD environment includes a review workstation and a primary CAD processor programmed with a primary CAD algorithm. Installed into the preexisting CAD environment is an auxiliary processing system programmed to receive a first CAD report from the primary CAD processor, apply an auxiliary CAD algorithm that is independent of the primary CAD algorithm to the underlying medical image, apply a voting algorithm to the primary and auxiliary CAD findings, and generate a second CAD report that includes the voting results. The second CAD report is configured to result in a rendering by the review workstation that is highly similar to a rendering that would result from the first CAD report except that the voted CAD findings are substituted in place of the primary CAD findings. | 05-05-2011 |
20110087132 | Needle Breast Biopsy System and Method for Use - A tilted needle biopsy assembly is provided for mounting on an x-ray system. Because the biopsy needle is angled relative to at least one of the detector and the x-ray source, x-ray imaging may be performed during the biopsy procedure without interference by the biopsy device. The angled biopsy needle additionally allows improved access to the axilla and chest wall of the patient. The stereotactic biopsy device of the present invention may be coupled to any x-ray system, whether upright or prone, including but not limited to mammography systems, tomosynthesis systems, and combination mammography/tomosynthesis systems. The system flexibly supports the use of any mode of image capture (i.e., scout, two dimensional mammogram, three-dimensional reconstructed volume) for either or both target visualization and target localization. With such an arrangement, a needle biopsy assembly having improved patient coverage is provided for use with a variety of different x-ray imaging platforms. | 04-14-2011 |
20110069809 | INTEGRATED MULTI-MODE MAMMOGRAPHY/TOMOSYNTHESIS X-RAY SYSTEM AND METHOD - A system for multi-mode breast x-ray imaging which comprises a compression arm assembly for compressing and immobilizing a breast for x-ray imaging, an x-ray tube assembly, and an x-ray image receptor is provided. The system is configured for a plurality of imaging protocols and modes. | 03-24-2011 |
20110069808 | X-RAY MAMMOGRAPHY WITH TOMOSYNTHESIS - A method and system for producing tomosynthetic images of a patient's breast. An x-ray source that delivers x-rays through a breast immobilized and compressed between a compression paddle and a breast platform and form an image at a digital x-ray receptor panel. Multiple x-ray images are taken as the x-ray source and the receptor move relative to the immobilized breast. In one preferred embodiment, the x-ray source travels from −15° to +15°. The source can travel in an arc around the breast while the receptor travels linearly while remaining parallel and at the same distance from the breast platform. The sets of x-ray image data taken at different angles are combined to form tomosynthetic images that can be viewed in different formats, alone or as an adjunct to conventional mammograms. | 03-24-2011 |
20110019887 | Displaying And Navigating Computer-Aided Detection Results On A Review Workstation - Display and navigation for multiple computer-aided detection (CAD) detections is described. A medical image is displayed to a viewer, and a request is received to instantiate CAD-assisted viewing. A timewise presentation sequence for the CAD detections is automatically computed according to a predetermined sequencing criterion. For each CAD detection, an expanded presentation window is displayed for its associated location in the medical image, the expanded presentation windows being displayed according to the timewise presentation sequence. Also described is a navigational tool comprising a plot of an operating curve onto which a computed feature associated with the CAD algorithm can be mapped, the operating curve characterizing an application of the CAD algorithm to a reference database of mammographic cases having known diagnoses. The navigational tool further comprises a plurality of CAD pointer icons spatially distributed therealong according to mappings of the computed feature for the CAD detections onto the operating curve. | 01-27-2011 |
20100246913 | COMPUTER-AIDED DETECTION OF ANATOMICAL ABNORMALITIES IN X-RAY TOMOSYNTHESIS IMAGES - Methods, systems, and related computer program products for computer-aided detection (CAD) of anatomical abnormalities in a breast volume based on a plurality of two-dimensional x-ray tomosynthesis projection images thereof is described. Each projection image is processed according to at least one predetermined feature extraction algorithm to generate at least one projection feature array corresponding thereto. For each of the at least one predetermined features extracted, the plurality of corresponding projection feature arrays is backprojected according to a predetermined tomosynthesis reconstruction algorithm to form a plurality of two-dimensional tomosynthesis reconstructed feature arrays. Each pixel in the three-dimensional breast geometry is then individually classified as being either a pixel of interest, or not a pixel of interest, based upon the at least one tomosynthesis reconstructed feature array value corresponding to that pixel. CAD detections for the breast volume are then generated based on the identified pixels of interest. | 09-30-2010 |
20100234719 | Estimating Visceral Fat By Dual-Energy X-Ray Absorptiometry - A system and a method of using dual-energy absoptiometry to estimate visceral fat metrics and display results, preferably as related to normative data. The process involves deriving x-ray measurements for respective pixel positions related to a two-dimensional projection image of a body slice containing visceral fat as well as subcutaneous fat; at least some of the measurements being dual-energy x-ray measurements, processing the measurements to derive estimates of metrics related to the visceral fat in the slice; and using the resulting estimates. | 09-16-2010 |
20100226475 | MAMMOGRAPHY/TOMOSYNTHESIS SYSTEMS AND METHODS AUTOMATICALLY DERIVING BREAST CHARACTERISTICS FROM BREAST X-RAY IMAGES AND AUTOMATICALLY ADJUSTING IMAGE PROCESSING PARAMETERS ACCORDINGLY - Methods and systems that automatically identify breast characteristics such as x-ray density and breast texture from initial x-ray images of the breast and automatically adjust process parameter setting of image processing algorithms that operate on the initial images to derive processing images suitable for display or further processing. | 09-09-2010 |
20100195882 | Matching Geometry Generation And Display Of Mammograms And Tomosynthesis Images - A method and a system for using tomosynthesis projection images of a patient's breast to reconstruct slice tomosynthesis images such that anatomical structures that appear superimposed in a mammogram are at conforming locations in the reconstructed images. | 08-05-2010 |
20100178711 | VIAL SYSTEM AND METHOD FOR PROCESSING LIQUID-BASED SPECIMENS - A vial-based system and method for handling and processing specimens of particulate matter-containing liquid directly in the vial. A processing assembly, which includes a stirrer and a particulate matter separation chamber, is releasably coupled to the inside of the vial cover. The processing assembly remains with the cover when the vial is opened to insert a specimen therein. Application of a particular external force to the closed vial detaches the processing assembly from the cover so that it remains in the vial, for access by automated or manual laboratory equipment, when the cover is subsequently removed. | 07-15-2010 |
20100150417 | PROCESSING MEDICAL IMAGES OF THE BREAST TO DETECT ANATOMICAL ABNORMALITIES THEREIN - Methods, systems and related computer program products are provided for processing a medical image of a breast to detect anatomical abnormalities therein, including anatomical abnormalities that may be associated with breast cancer. The medical image of the breast, which includes a background region bordering a breast tissue region along a skinline thereof, is processed to detect an inward-facing retraction along the skinline, which can be potentially indicative of an anatomical abnormality in the breast tissue. In one preferred embodiment, a display monitor displays first information representative of the medical image of the breast and second information identifying a location of the detected inward-facing retraction on the medical image of the breast. In another preferred embodiment, one or more metrics characterizing the detected inward-facing retraction are used as features in the classification of potential CAD detections in the breast tissue region. | 06-17-2010 |
20100150306 | Mammography System And Method Employing Offset Compression Paddles, Automatic Collimation, And Retractable Anti-scatter Grid - A mammographic imaging system is optimized for use with a single fixed size flat panel digital image receptor. It accommodates compression devices (paddles) of varying sizes, and positions them properly in the field of view of the image receptor. When a compression paddle with size smaller than the field of view of the image receptor is used, the compression paddle can be shifted laterally in the direction parallel to the chest wall, so as to facilitate different views of different size breasts, and permit the image receptor to image as much of the desired tissue as possible. An automatic x-ray collimator restricts the x-ray illumination of the breast in accordance with compression paddle size and location in the field of view. An anti-scatter grid, mounted inside the image receptor enclosure, just below the top cover of the enclosure, can be retracted out of the field of view of the image receptor for use in magnification imaging. | 06-17-2010 |
20100135456 | Full Field Mammography With Tissue Exposure Control, Tomosynthesis, and Dynamic Field of View Processing - A mammography system using a tissue exposure control relying on estimates of the thickness of the compressed and immobilized breast and of breast density to automatically derive one or more technic factors. The system further uses a tomosynthesis arrangement that maintains the focus of an anti-scatter grid on the x-ray source and also maintains the field of view of the x-ray receptor. Finally, the system finds an outline that forms a reduced field of view that still encompasses the breast in the image, and uses for further processing, transmission or archival storage the data within said reduced field of view. | 06-03-2010 |
20100086188 | Breast Tomosynthesis With Display Of Highlighted Suspected Calcifications - Systems and methods that facilitate the presentation and assessment of selected features in projection and/or reconstructed breast images, such as calcifications that meet selected criteria of size, shape, presence in selected slice images, distribution of pixels that could be indicative of calcification relative to other pixels or of other image features of clinical interest. | 04-08-2010 |
20100054400 | MULTI-MODE TOMOSYNTHESIS/MAMMOGRAPHY GAIN CALIBRATION AND IMAGE CORRECTION USING GAIN MAP INFORMATION FROM SELECTED PROJECTION ANGLES - A multi-mode tomosynthesis/mammography system and method in which a mammography gain map is used to gain correct mammographic images of a patient's breast but enhanced gain maps for respective projection angled are used to correct tomosynthesis images acquired with the same system. | 03-04-2010 |
20100020393 | System and Device for Non-Destructive Raman Analysis - An improved Raman microspectrometer system extends the optical reach and analysis range of an existing Raman microspectrometer to allow analysis and/or repair of an oversized sample. The improved Raman microspectrometer system includes an extender for extending the optical reach of the existing microspectrometer and a supplemental stage which extends the analysis range of the existing microspectrometer by providing travel capabilities for non-destructive analysis of an entire oversized sample. Such an arrangement decreases manufacturing costs associated with testing oversized samples such as mammography panels, enabling analysis and/or repair to be performed without destruction. | 01-28-2010 |
20090304147 | X-RAY MAMMOGRAPHY/TOMOSYNTHESIS OF PATIENT'S BREAST - A breast x-ray system and method using tomosynthesis imaging in which the x-ray source generally moves away from the patient's head. The system may include an operation mode in which it additionally takes mammogram image data. | 12-10-2009 |
20090296882 | Image Handling And Display In X-Ray Mammography And Tomosynthess - A method and system for acquiring, processing, storing, and displaying x-ray mammograms Mp tomosynthesis images Tr representative of breast slices, and x-ray tomosynthesis projection images Tp taken at different angles to a breast, where the Tr images are reconstructed from Tp images | 12-03-2009 |
20090253142 | COMPOSITIONS AND METHODS FOR ANALYSIS OF NUCLEIC ACID MOLECULES DURING AMPLIFICATION REACTIONS - The present invention provides systems, methods and kits for performing a detection assay (e.g., invasive cleavage assay) in combination with an amplification assay (e.g., PCR), where the detection assay employs enzyme footprint probes with relatively short (e.g., 6-12 bases) analyte-specific regions configured to provide a preferred footprint length of duplex for use with a particular nucleic acid modifying enzyme. In some embodiments, such assays are used for target quantification, and in other embodiments, such assays are used for genotyping. In certain embodiments, the use of such short probes allows for assays with increased dynamic range. | 10-08-2009 |
20090245460 | Mammography System And Method Employing Offset Compression Paddles, Automatic Collimation, And Retractable Anti-scatter Grid - A mammographic imaging system is optimized for use with a single fixed size flat panel digital image receptor. It accommodates compression devices (paddles) of varying sizes, and positions them properly in the field of view of the image receptor. When a compression paddle with size smaller than the field of view of the image receptor is used, the compression paddle can be shifted laterally in the direction parallel to the chest wall, so as to facilitate different views of different size breasts, and permit the image receptor to image as much of the desired tissue as possible. An automatic x-ray collimator restricts the x-ray illumination of the breast in accordance with compression paddle size and location in the field of view. An anti-scatter grid, mounted inside the image receptor enclosure, just below the top cover of the enclosure, can be retracted out of the field of view of the image receptor for use in magnification imaging. | 10-01-2009 |
20090141859 | Image Handling and Display in X-Ray Mammography and Tomosynthesis - A method and system for acquiring, processing, storing, and displaying x-ray mammograms Mp tomosynthesis images Tr representative of breast slices, and x-ray tomosynthesis projection images Tp taken at different angles to a breast, where the Tr images are reconstructed from Tp images | 06-04-2009 |
20090010384 | FULL FIELD MAMMOGRAPHY WITH TISSUE EXPOSURE CONTROL, TOMOSYNTHESIS, AND DYNAMIC FIELD OF VIEW PROCESSING - A mammography system using a tissue exposure control relying on estimates of the thickness of the compressed and immobilized breast and of breast density to automatically derive one or more technic factors. The system further uses a tomosynthesis arrangement that maintains the focus of an anti-scatter grid on the x-ray source and also maintains the field of view of the x-ray receptor. Finally, the system finds an outline that forms a reduced field of view that still encompasses the breast in the image, and uses for further processing, transmission or archival storage the data within said reduced field of view. | 01-08-2009 |