GLYCOTOPE GmbH Patent applications |
Patent application number | Title | Published |
20150118354 | MICROORGANISMS OF THE SPECIES BACTEROIDES XYLANISOLVENS - The present invention pertains to food products comprising microorganisms of the species | 04-30-2015 |
20150010495 | METHOD FOR THE PRODUCTION OF AN IMMUNOSTIMULATING MUCIN (MUC1) - The present invention relates to a method for producing or identifying a MUC1 molecule which is able to generate an immune response in humans. The invention also relates to a method for producing or identifying a cell, cell lines or cell lysates containing a MUC1 molecule that is able to generate an immune response in humans. The invention further relates to methods for producing medicaments and diagnostic agents. Also disclosed is the use of the MUC1 molecules, cells or cell lysates obtained by means of the methods according to the invention for producing a medicament used for treating or preventing tumours. Further disclosed is a purified MUC1 molecule that can be obtained by means of the methods according to the invention and has an immunostimulating effect on humans. The invention additionally relates to the use of a MUC1 antibody for the production of a medicament used for treating or preventing tumours. | 01-08-2015 |
20140302093 | MICROORGANISMS CARRYING A TUMOR ANTIGEN - The present invention pertains to microorganisms of the species | 10-09-2014 |
20140099259 | TUMOR-SPECIFIC RECOGNITION MOLECULES - The invention relates to recognition molecules which are directed towards tumors and can be used in the diagnosis and therapy of tumor diseases. | 04-10-2014 |
20130330768 | METHODS FOR CULTURING HUMAN MYELOID LEUKAEMIA CELLS AND CELLS DERIVED THEREFROM - The present invention pertains to a method for culturing a suspension of immortalized human blood cells, preferably cells of myeloid leukaemia origin or cells derived therefrom, wherein said method provides a high productivity, a high cell viability and growth rate and a high batch-to-batch consistency, and can be scaled up without altering these parameters. | 12-12-2013 |
20130273033 | HUMANIZED EGFR ANTIBODIES - The present invention pertains to humanized anti-EGFR antibodies having antigen binding properties similar to those of the murine or chimeric anti-EGFR antibody from which they are derived. In particular, the present invention is directed to humanized anti-EGFR antibodies which are useful in the treatment of cancer. | 10-17-2013 |
20130209458 | FAB-GLYCOSYLATED ANTIBODIES - The present invention pertains to a method for controlling the circulation half-life of antibodies by adjusting the amount of sialic acid in the carbohydrates attached to the Fab part of the antibodies. Furthermore, the present invention provides antibodies having an increased circulation half-life. | 08-15-2013 |
20130137636 | RECOMBINANT HUMAN FOLLICLE-STIMULATING HORMONE - The present invention pertains to improved FSH preparations which are capable of stimulating sex steroid release at much lower concentration than the commonly used urinary FSH or recombinant FSH obtained from CHO cells and which act independent of cAMP signaling These improved FSH preparations can be used in infertility treatment. | 05-30-2013 |
20120329092 | PROCESS FOR THE PURIFICATION OF GLYCOPROTEINS - The present invention relates to a process for the purification of a glycoprotein comprising subjecting a liquid containing said glycoprotein to the steps of:
| 12-27-2012 |
20120308607 | PRODUCTION AND USE OF HUMAN CD124- AND CD-116-POSITIVE TUMOR CELL LINES IN THE PRODUCTION OF ALLOGENIC OR SEMI-ALLOGENIC IMMUNOTHERAPY AGENTS - The invention is related to the production and use of CD124+ and CD116+ cell lines for the production of effective dendritic cells (DC) using stimulatory molecules, their use in the production of allogenic or semi-allogenic immunotherapeutic agents and the use thereof in the treatment or prophylaxis of immune diseases. Furthermore, the invention is related to the use of CD124+ and CD116+ tumor cell lines, preferably also being CD34+, as model and yeast systems for testing the DC biology and for testing substances having an impact on the immune system and on the conditioning thereof. | 12-06-2012 |
20120294859 | CANCER STEM CELL MARKERS AND USES THEREOF - The present invention inter alia pertains to therapeutic methods which are based on the use of an agent specifically binding a tumor-associated carbohydrate antigen for the treatment of cancer stem cells and related diseases. Also provided are diagnostic and prognostic methods using a tumor-associated carbohydrate antigen as marker for cancer stem cells. | 11-22-2012 |
20120252069 | PROCESS FOR THE PURIFICATION OF GLYCOPROTEINS - The present invention relates to a process for the purification of a glycoprotein comprising subjecting a liquid containing said glycoprotein to the steps of: a) reverse phase chromatography, b) size exclusion chromatography, and c) hydrophobic interaction chromatography. Also provided is a manufacturing process for producing a glycoprotein of interest. | 10-04-2012 |
20120149877 | TUMOR-SPECIFIC RECOGNITION MOLECULES - The invention relates to recognition molecules which are directed towards tumors and can be used in the diagnosis and therapy of tumor diseases. | 06-14-2012 |
20120128676 | MUC1 ANTIBODIES - The present invention pertains to anti-mucin antibodies having improved antigen binding and/or recognition properties as well as a method for improving the antigen binding and/or recognition of an anti-mucin antibody. In particular, the present invention is directed to anti-MUC1 antibodies which are useful in the treatment of cancer. | 05-24-2012 |
20120100576 | PERFUSION BIOREACTOR - The present invention pertains to a system for culturing cells comprising a culturing bag and a continuous flow centrifuge wherein the cells are continuously separated from the supernatant and are recycled into the culturing bag. Further provided are methods for culturing cells and for producing a biological substance using the device for culturing cells, and the use of a bag for culturing cells in said device or said methods. In particular, a perfusion system for culturing cells is provided wherein the wave technology for culturing cells is combined with continuous flow centrifugation for separating the medium from the cells. | 04-26-2012 |
20110319590 | Tumour Cell Lines and Uses Thereof - The present invention relates to a cell line selected from the group consisting of (a) a cell line denominated NM-F9 having the DSMZ accession number DSM ACC2606; (b) a cell line denominated NM-D4 having the DSMZ accession number DSM ACC2605; and subclones of (a) or (b). Additionally, the present invention provides a lysate of the cell lines or a molecule or mixture of molecules obtained from these cell lines as well as dendritic cells loaded with said lysate, co-cultivated or fused with cells from the cell lines, or a molecule or mixture of molecules obtained from these cell lines of the present invention. Moreover compositions, preferably pharmaceutical or vaccine compositions are provided which comprise the cell lines, lysate, molecules, mixture of molecules or dendritic cells of the present invention. In another aspect the present invention relates to methods for producing the aforementioned compositions. Furthermore, methods and uses for vaccination against or treatment or prevention of cancers and/or tumourous diseases are provided. | 12-29-2011 |