FONDAZIONE CARIPLO Patent applications |
Patent application number | Title | Published |
20150119342 | New Homo- and Heterodimeric SMAC Mimetic Compounds as Apoptosis Inducers - The present invention relates to conformationally constrained homo- and heterodimeric mimetics of Smac with function as inhibitors of Inhibitor of Apoptosis Proteins (IAPs), the invention also relates to the use of these compounds in therapy, wherein the induction of apoptotic cell death is beneficial, especially in the treatment of cancer, alone or in combination with other active ingredients. | 04-30-2015 |
20140179893 | BRANCHED LACTIC ACID POLYMERS WITH HIGH VISCOSITY IN THE MOLTEN STATE AND HIGH SHEAR SENSITIVITY, AND NANOCOMPOSITES THEREOF - Disclosed is a polymer obtainable by bulk polymerization of lactide or lactic acid or a lactic acid copolymer obtainable by copolymerization of lactide or lactic acid with glycolide, glycolic acid and/or hydroxyacids in open or closed (cyclic) form in the presence of at least two organic and/or organic/inorganic chain regulators or a functionalized nanoparticle (nanosilica, montmorillonite). | 06-26-2014 |
20140128343 | COMPLEX OF AMORPHOUS TOMOXIPROLE AND CYCLODEXTRIN WITH FAST DISSOLUTION RATE AND PROCESS FOR THE PREPARATION THEREOF - A stable complex of tomoxiprole with 2-hydroxypropyl-beta-cyclodextrin with fast dissolution rate and rapid absorption wherein amorphous tomoxiprole forms a complex with 2-hydroxypropyl-beta-cyclodextrin in about equimolecular ratio. The complex shows a remarkably faster dissolution rate and absorption with respect to crystalline tomoxiprole and is particularly suitable for the production of pharmaceutical oral dosage forms, such as tablets and capsules, where rapid onset of therapeutical action is required. A method of manufacture of the complex is also described and claimed. | 05-08-2014 |