ETH ZURICH Patent applications |
Patent application number | Title | Published |
20160130729 | Improved Spinning Process and Novel Gelatin Fibers - The present invention relates to the manufacturing gelatin fibers comprising the steps of: (a) preparing a two-phase composition as defined in the claims, (b) spinning the lower phase of said composition, (c) stretching the obtained fiber and (d) optional finishing steps; to new gelatin fibers and to the use thereof. | 05-12-2016 |
20160093872 | METHOD FOR THE PRODUCTION OF ELECTRODES AND ELECTRODES MADE USING SUCH A METHOD - A method for the manufacturing of electrodes with at least one porous surfacial layer comprising anisotropic electrochemically active particles. It also relates to electrodes made using such a method. The method comprises the following steps: (a) coupling of paramagnetic nanoparticles to said active particles for the generation of composites; (b) preparation of a slurry of said composites, including a solvent mixed with a binder able to release a volatile component; (c) application of said slurry to a substrate to form a film; (d) application of a magnetic field to the film and orienting said active particles leading to a substrate in which said active particles are arranged with their shortest axes aligned along a preferred axis parallel to said substrate; (e) during or after application of said magnetic field evaporation of said solvent with solidification of the binder and release of said volatile component under formation of said surfacial layer. | 03-31-2016 |
20160087196 | Strained Multilayer Resistive-Switching Memory Elements - The resistive-switching memory element of the present invention comprises a first electrode, a resistive-switching element; and a second electrode wherein the resistive-switching element is arranged between the first electrode and the second electrode and the resistive-switching element comprises, or consists of a plurality of metal oxide layers and wherein neighboring metal oxide layers of the resistive-switching element comprise, or consist of, different metal oxides. | 03-24-2016 |
20160086459 | Fibre Optic Based Intrusion Sensing System - A fiber optic based intrusion sensing system includes two or more fiber optic cables buried in a shallow trench in the ground, side by side in a predetermined nonzero distance to each other and at one or more predetermined depths. A dynamic distributed fiber optic interrogator measures a predetermined property related to a change in the length of the cables connected to it. A control unit is connected to all interrogators and analyzes the measurements of the predetermined property and identifies objects on the surface by combining the simultaneous measurements of all cables and correlating the measurements to the type of object on the ground surface, the location of the object on the perimeter, the weight, speed and direction of the object, particularly the direction in or out of the secured perimeter. | 03-24-2016 |
20150367588 | APPARATUS AND METHOD FOR VERTICAL SLIP FORMING OF CONCRETE STRUCTURES - Apparatus ( | 12-24-2015 |
20150320632 | APPARATUS FOR UNLOADING A USER'S BODY WEIGHT DURING A PHYSICAL ACTIVITY OF SAID USER, PARTICULARLY FOR GAIT TRAINING OF SAID USER - The invention relates to an apparatus ( | 11-12-2015 |
20150291760 | METHOD FOR THE PREPARATION OF MACROPOROUS PARTICLES AND MACROPOROUS - A method for producing macro porous micro-clusters is proposed comprising at least the following individual steps in given order: a) synthesis of dispersed cross-linked polymeric latex primary particles starting from at least one monomer or oligomer using emulsion polymerization; b) swelling of the primary particles with a liquid comprising at least an additional charge of monomer and/or oligomer and a cross-linker, optionally further comprising functionalization agents; c) destabilization by increase of ionic strength (by adding a salt and/or acid and/or base) in a combination with application of shear, both being above the gel formation boundary of the phase diagram, until agglomerates composed of primary particles of the desired size are formed; d) polymerization of the agglomerates to form the macro porous micro-clusters. Furthermore the invention to relates to correspondingly produced micro-clusters and uses of such micro-clusters in particular for chromatographic purposes. | 10-15-2015 |
20150290327 | SULFATED ALGINATE HYDROGELS FOR CELL CULTURE AND THERAPY - The present invention relates to a method for providing an embedded mammalian cell, comprising the steps of providing an alginate sulfate in aqueous solution; reacting the alginate sulfate to form a hydrogel in a gelation step, providing a precursor cell, and embedding the precursor cell in the sulfated alginate hydrogel in an embedding step, thus yielding an sulfated alginate hydrogel embedded cell. The invention further relates to sulfated alginate hydrogels, and cellular grafts comprising a mammalian cell embedded in sulfated alginate hydrogel. | 10-15-2015 |
20150231528 | METHOD AND APPARATUS FOR MULTI COLUMN CHROMATOGRAPHIC PURIFICATION - A method for separating a feed mixture comprising at least two solutes by an intermittent multi column chromatography process with a basic step N performed in a predetermined switching time period. Basic step N comprises two sub steps which are carried out sequentially according to a predetermined step ratio. In sub step one inlet ports and outlet ports are open, a desorbent and a feed mixture enters upstream of a first and a third section. A first outlet stream comprising the desorbent and at least one solute is withdrawn downstream of the first section a second outlet stream comprising the desorbent and at least a further solute is withdrawn downstream of a the third section. In sub step two inlet ports and outlet ports are closed, a fluid stream comprising the desorbent part of the feed mixture circulates through three sections in a closed loop. | 08-20-2015 |
20150218337 | COMPOSITE MATERIALS AND THEIR USES AS WELL AS METHODS FOR THE PREPARATION THEREOF - A reinforced composite material based on a polymer matrix with reinforcement particles embedded therein. The polymer matrix is based on a polymer with soft and hard domains, and the reinforcement particles comprise inorganic nano-platelets in the polymer matrix in a volume fraction in the range of 0.01%-50%, the inorganic nano-platelets have a thickness in the range of 0.3-50 nm, with the proviso that the largest length and width is at least twice as large as the thickness; as well as inorganic micro-platelets in a volume fraction in the range of 1%-90%, wherein the inorganic micro-platelets have a thickness in the range of 10 nm-100 μm, with the proviso that the largest length and width is at least twice as large as the thickness. Also disclosed are multilayer structures based on such layers, methods for making such multilayer structures and uses thereof. | 08-06-2015 |
20150203828 | N-GLYCAN CORE BETA-GALACTOSYLTRANSFERASE AND USES THEREOF - The present invention relates to new galactosyltransferases, nucleic acids encoding them, as well as recombinant vectors, host cells, antibodies, uses and methods relating thereto. | 07-23-2015 |
20150078620 | Aircraft, Methods for Providing Optical Information, Method for Transmission of Acoustic Information and Method for Observing or Tracking an Object - Provided is an aircraft having a spherical body which generates buoyancy or which may generate buoyancy when filled with gas, wherein the aircraft further comprises four actuation units arranged on the surface of the body for movement of the aircraft in a translation and/or rotation through air, and at least one camera arranged on or in the surface of the body. Further provided is a method for providing optical information to a person in the environment of a flying aircraft, a method for providing optical information about an object and/or surveying of an object, a method for transmission of acoustic information and a method for observing or tracking an object. | 03-19-2015 |
20150057676 | MAGNETIC NAVIGATION SYSTEM WITH SOFT MAGNETIC CORE ELECTROMAGNETS FOR OPERATION IN THE NON-LINEAR REGIME - The present invention relates to a magnetic manipulation and navigation system for moving a magnetic element through a body comprising at least six electromagnets ( | 02-26-2015 |
20150038892 | PATCH STRUCTURES FOR CONTROLLED WOUND HEALING - The invention relates to an active surface element ( | 02-05-2015 |
20150030545 | MOLECULAR CODE SYSTEMS - The present invention relates to a method for protecting and. recovering nucleic acids. This method may be applied in a verification method of products using molecular code systems or it may be applied in a storage method for nucleic acids. The invention further provides specific particles, their use in secure marking; products suitable for such verification method, to processes for manufacturing such products and methods for reading the information. | 01-29-2015 |
20150009277 | METHOD AND SYSTEM FOR IMAGE PROCESSING IN VIDEO CONFERENCING - A method for image processing in video conferencing, for correcting the gaze of an interlocutor in an image or a sequence of images captured by at least one real camera, comprises the steps of
| 01-08-2015 |
20140335127 | SYSTEM AND METHOD FOR THE PRODUCTION OF RECOMBINANT GLYCOSYLATED PROTEINS IN A PROKARYOTIC HOST - A system and a method for the production of recombinant N-glycosylated target proteins. The system comprises a prokaryotic organism (e.g. | 11-13-2014 |
20140323700 | RECOMBINANT N-GLYCOSYLATED PROTEINS FROM PROCARYOTIC CELLS - The present invention relates to recombinant N-glycosylated proteins, comprising one or more introduced N-glycosylated optimized amino acid sequence(s), nucleic acids encoding these proteins as well as corresponding vectors and host cells. In addition, the present invention is directed to the use of said proteins, nucleic acids, vectors and host cells for preparing medicaments. Furthermore, the present invention provides methods for producing said proteins. | 10-30-2014 |
20140322732 | METHOD FOR BIOMARKER AND DRUG-TARGET DISCOVERY FOR PROSTATE CANCER DIAGNOSIS AND TREATMENT AS WELL AS BIOMARKER ASSAYS DETERMINED THEREWITH - The invention relates to a method for the determination of a cancer diagnostic/therapeutic biomarker assay and drug-targets including the following steps: (a) identification of potential candidate protein/peptide biomarkers and drug-targets based on the measurement of protein/peptide constituent concentrations in tissue sample proteomes as well as serum, plasma or any other derivatives of blood, or blood itself sample proteomes derived from healthy non-human mammalian individuals as well as from cancerous non-human mammalian individuals and qualitatively selecting as potential candidate protein/peptide biomarkers those which show a pronounced differential behaviour between healthy and cancerous sample proteomes; (b) optional verification of the potential candidate protein/peptide biomarkers as identified in step (a) by quantitative mass spectrometric measurement of the potential candidate protein biomarkers in serum, plasma or any other derivatives of blood, or blood itself sample proteomes derived from healthy non-human mammalian individuals as well as from cancerous non-human mammalian individuals and selecting as candidate protein/peptide biomarkers those which show a mass-spectrometrically measurable quantitative differential behaviour between healthy and cancerous sample proteomes; (c) validation of the candidate protein/peptide biomarkers as identified in step (a), or as optionally verified in step (b), by mass spectrometric measurement and/or antibody-based assays such as an Enzyme-Linked Immunosorbent Assay (ELISA) determination of the candidate protein biomarkers in serum, plasma or any other derivatives of blood, or blood itself sample proteomes derived from healthy human individuals as well as from cancerous human individuals and selecting as protein/peptide biomarkers those which show a mass-spectrometrically measurable and/or antibody-based assay detectable differential behaviour between healthy and cancerous sample proteomes; (d) application of statistical methods to uncover single or groups of protein/peptide biomarkers as validated in step (c) as signatures for the detection of patients with cancer. The invention furthermore relates to specific biomarker assays for the highly reliable diagnosis of cancer, specifically of localized or non-localized prostate cancer, using human serum, plasma or any other derivatives of blood, or blood itself. | 10-30-2014 |
20140316748 | Posture Guided Design Of Deformable Objects - There is provided a posture guided design system and a method for use in producing a posture guided design of a deformable object. In one implementation, such a method includes identifying a target posture for the deformable object, and determining locations of actuators for producing the target posture. The method also includes modeling the deformable object using at least one material so as to enable the deformable object to substantially reproduce the target posture. In some implementations, the method includes modeling the deformable object using at least two materials, wherein a distribution of the at least two materials is determined so as to enable the deformable object to substantially reproduce the target posture. | 10-23-2014 |
20140287433 | MEANS AND METHODS FOR DETERMINING CLOSTRIDIAL NEUROTOXINS - This invention relates to a method of determining presence, amount and/or activity of a clostridial neurotoxin in a sample, the method comprising or consisting of the following steps: (a) bringing said sample into contact with a liposome, said liposome comprising (aa) at least one receptor on its outer surface, said receptor being capable of binding said neurotoxin and comprising or consisting of (i) a glycolipid and (ii) a peptide or protein; and (ab) a substrate in its interior, said substrate (i) being cleavable by the peptidase comprised in said neurotoxin and (ii) generating a detectable signal upon cleavage, said detectable signal preferably being generated by (1) the donor of a FRET pair, said donor exhibiting increased fluorescence upon cleavage by said peptidase, (2) a luminescent compound formed upon said cleavage, or (3) an enzyme formed upon said cleavage; and (b) determining whether an increase in signal occurs as compared to the absence of said sample, wherein such increase is indicative of the presence of said neurotoxin and/or the degree of such increase is indicative of the amount and/or activity of said neurotoxin in said sample. | 09-25-2014 |
20140252899 | ROTATING ELECTRICAL MACHINE AND METHOD FOR MEASURING A DISPLACEMENT OF A ROTOR OF A ROTATING ELECTRICAL MACHINE - A rotating electrical machine includes a stator, a rotor and at least one active magnetic bearing including a bearing winding, which is an air-gap winding, and includes at least a first phase winding and a second phase winding. A measurement arrangement measures the radial displacement of the rotor by injecting a displacement measurement injected signal into at least one section of at least one of the bearing windings of one of the magnetic bearings, and capturing at least one displacement measurement signal wherein this displacement measurement signal depends on the rotor displacement in a radial direction relative to the stator, this dependency being due to eddy currents in the rotor induced by the displacement measurement injected signal. | 09-11-2014 |
20140235590 | PHARMACEUTICAL COMPOUNDS FOR USE IN THE THERAPY OF CLOSTRIDIUM DIFFICILE INFECTION - The invention relates to a compound described by a general formula (1), wherein each X independently can be OPO | 08-21-2014 |
20140234903 | BIOSYNTHETIC GENE CLUSTER FOR THE PRODUCTION OF PEPTIDE/PROTEIN ANALOGUES - A novel gene cluster encoding polypeptides involved in the generation of bio synthetically unique peptide-based compounds is described. In addition, new methods for biosynthetic engineering and production of modified peptides and proteins are disclosed. Furthermore, new tools for identification of homologue polypeptides and precursor peptides in other species are provided. In addition, peptide-based compounds and fusions of these compounds with functional moieties for treatment of disorders such as tumors are disclosed. | 08-21-2014 |
20140205761 | METHOD FOR NANO-DRIPPING 1D, 2D OR 3D STRUCTURES ON A SUBSTRATE - A method for the production of nano- or microscaled ID, 2D and/or 3D depositions from an solution ( | 07-24-2014 |
20140194346 | PASTEURELLACEAE VACCINES - The present invention relates to an N-glycosylated protein for treating and/or preventing bacterial Pasteurellaceae infection in a mammal or bird, wherein the protein is a Pasteurellaceae protein, a functional fragment or derivative thereof having at least one glycosylated N-X-S/T consensus sequence. In addition, the present invention is directed to corresponding pharmaceutical compositions for treating and/or protecting mammals or birds having or being prone to develop a bacterial Pasteurellaceae infection. Furthermore, the invention describes methods for producing said N-glycosylated proteins. | 07-10-2014 |
20140186445 | METHOD FOR MAKING CUSTOMISED NANOPARTICLES, NANOPARTICLES AND USES THEREOF - A method for the production of biodegradable nanoparticles with an average particle size of less than 400 nm. In a first step, a macromonomer is prepared in a ring opening polymerization process between a hydrophilic acrylate compound (A) as an initiator and hydrophobic cyclic monomers (B), wherein the macromonomer comprises at least two repetitive units based on the cyclic monomer. In a second step, this macromonomer or a mixture of macromonomers and/or commercial biocompatible monomers is polymerized, e.g. in a starved, miniemulsion or emulsion radical polymerization in water in the presence of a surfactant to the nanoparticle without necessitating additional subsequent steps for the actual production of the nanoparticles. The correspondingly made nanoparticles and uses thereof also are disclosed. | 07-03-2014 |
20140178498 | METHOD FOR GENERATION OF NANOPARTICLES COMPOSITE FILMS AND FILMS MADE USING SUCH A METHOD - Proposed is a method for the production of at least one composite layer ( | 06-26-2014 |
20140151582 | Droplet Dispensing Device and Light Source Comprising Such a Droplet Dispensing Device - A droplet dispensing device includes a reservoir for receiving a liquid material, an outlet nozzle in fluid communication with the reservoir and a piezoelectric actuating means acting on the liquid material at the outlet nozzle to exit the outlet nozzle in a sequence of droplets. A piezoelectric actuating means that includes a piston, which is actuated by a piezoelectric actuator at one end and dips the other, free end into the liquid material is provided just upstream of the outlet nozzle. | 06-05-2014 |
20140113953 | Targeting MicroRNAs for Metabolic Disorders - Provided herein are methods and compositions for the treatment of metabolic disorders. Also provided herein are methods and compositions for the reduction of blood glucose level, the reduction of gluceoneogenesis, the improvement of insulin resistance and the reduction of plasma cholesterol level. In certain embodiments, the methods comprise inhibiting the activity of miR-103. In certain embodiments, the methods comprise inhibiting the activity of miR-107. In certain embodiments, the activity of both miR-103 and miR-107 is inhibited. In certain embodiments, such methods comprise administering a compound comprising an oligonucleotide targeted to a microRNA. | 04-24-2014 |
20140100836 | RATIONAL DESIGN OF COMPONENTS OF THE OLIGO-SACCHARYLTRANSFERASE-CATALYSED ASPARAGINE-LINKED GLYCOSYLATION - The present invention is directed to methods for identifying or designing (a) a potential oligosaccharide donor, (b) a potential oligosaccharyltransferase (OST), (c) a potential consensus sequence motif polypeptide, and/or (d) a potential glycosylation inhibitor for use in the oligosaccharyltransferase (OST)-catalysed asparagine-linked (“N-linked”) glycosylation, comprising the steps of generating a three-dimensional model of the catalytic domain and/or the polypeptide binding site of the oligosaccharyltransferase (OST) of | 04-10-2014 |
20140100278 | Injectable Formulation for Treatment and Protection of Patients Having an Inflammatory Reaction or an Ischemia-Reperfusion Event - The present invention relates to compounds according to formula (I) for medical use. The compounds are particularly suitable for the treatment and/or prevention of a medical condition involving hypoxic, anoxic and/or inflamed mammalian tissue. Furthermore, the invention relates to the use of said compounds for preparing a medicament and to pharmaceutical preparations comprising such compounds. The invention also relates to methods of treating or protecting patients having or being prone to develop a medical condition involving hypoxic, anoxic and/or inflamed mammalian tissue, the methods comprising administration of a therapeutically effective amount of such compounds. | 04-10-2014 |
20140082696 | DISTANCE BOUNDING PROTOCOL WITH MINIMAL VARIANCE PROCESSING - The method for communicating between a first device and a second device, the first and second devices being structured and configured for communicating via a communication channel by exchanging messages, comprises the steps of
| 03-20-2014 |
20140059709 | CONTROL OF URIC ACID HOMEOSTASIS - The invention relates to vectors and mammalian cells in a system useful for switching on or switching off gene expression in response to uric acid. In a particular embodiment the invention relates to a mammalian cell useful in detecting and/or degrading a harmful excess of uric acid comprising (a) a vector comprising a genetic code for the uricase sensor-regulator HucR from | 02-27-2014 |
20130302832 | METHOD FOR ELECTRICAL DETECTION OF BIOMOLECULES BY METAL DISSOLUTION AND ASSAY KIT THEREFORE - The present invention relates to a method for detecting a target molecule in a sample by metal dissolution as described in the specification, said method using an electrical readout; to kits adapted for this method and to electrodes suitable for such kits and methods. | 11-14-2013 |
20130207000 | Laser-Ablation Ion Source with Ion Funnel - A laser-ablation ion source for generating a low energy ion beam having low longitudinal and transverse emittance, including a supersonic nozzle, followed by an RF ion funnel. A laser source generates a laser beam which is focused by a lens to an ablation site. The ablation site is located upstream of the nozzle, at a distance of less than 10 mm from the nozzle aperture. The laser irradiates the ablation site through the nozzle aperture to generate the ions. | 08-15-2013 |
20130197882 | EVALUATING AND OPTIMIZING A TRAJECTORY FUNCTION - A method for evaluating a trajectory function to be followed by a physical system includes providing the trajectory function; determining a set of sampling points by sampling a trajectory based on the trajectory function in the time domain; associating a cell to each of the sampling points; assessing at least one cell metric for each of the cells; aggregating the at least one cell metric of the cells to obtain an aggregated metric measure; and evaluating the trajectory as determined by the provided trajectory function depending on the one or more aggregated metric measures. | 08-01-2013 |
20130165397 | TREATMENT OF BACTERIAL INFECTIOUS DISEASES - The present invention relates to a novel pharmacological treatment of bacterial infectious diseases in humans. Specifically the invention relates to the use of apramycin of formula (I) or apramycin derivatives to treat bacterial infectious diseases in humans. It is demonstrated that apramycin surprisingly does not have the expected high level of toxicity observed with related aminoglycoside antibiotics but actually is even significantly less toxic than compounds already used in human medicine such as gentamicin. | 06-27-2013 |
20130123756 | Prevention of Bacterial Adherence and Growth in an Urological Implant - A medical device is disclosed, which comprises a functional unit (C) for permanent or temporary placement in the urogenital tract of a human or animal body. The functional unit has at least one electrically conducting portion. A power source (G) supplies a current to the electrically conducting portion after placement of the functional unit in the urogenital tract. In this manner, the growth of bacteria on the functional unit can be reduced. | 05-16-2013 |
20130105034 | METHOD FOR SPATIALLY MANIPULATING A MICROSCOPIC OBJECT AND DEVICE FOR CONDUCTING SAID METHOD | 05-02-2013 |
20130102252 | METHOD FOR COMMUNICATING AND DISTANCE BOUNDING SYSTEM - The method for communicating between a first device and a second device includes the steps of: the first and second device communicating by exchanging messages that are based on signals that are transmitted through a plurality of communication channels; the first device sending a challenge message to the second device over one communication channel; the second device sending, upon reception of the challenge message, a response message to the first device through at least two communication channels that have essentially identical signal propagation velocities; the first device measuring the time elapsed between the sending of the challenge message to the reception of the response message; and the first device computing its distance to the second device based on this time, knowledge about travelling speed of the challenge and the response message and the processing delay that the second device adds to generate and send the response message. | 04-25-2013 |
20130058870 | 3D NANOCRYSTALS AND MANUFACTURING METHODS - The invention relates to nanocrystals, containing one or more metals as defined in the specification; having a size of 2 to 200 nm; having a defined, three-dimensional polyhedral structure, optionally functionalized by ligands and/or embedded crystals. The invention further relates to monodisperse assemblies of such nanocrystals, to formulations and devices comprising such nanocrystals as well as to the manufacture and use thereof. | 03-07-2013 |
20130057332 | SWITCHING DEVICE HAVING A JFET SERIES CIRCUIT - A switching device for switching a current between a first connection and a second connection including a series circuit of at least two JFETs (J | 03-07-2013 |
20130053471 | METHOD FOR THE PRODUCTION OF REINFORCED MATERIALS AND REINFORCED MATERIALS OBTAINED USING THIS METHOD - A method for making a composite material with non-spherical reinforcing particles embedded in a matrix, is disclosed. In this method, in a first step magnetic and/or superparamagnetic nanoparticles are attached to the non-spherical reinforcing particles, in a second step the resulting reinforcing particles are introduced into a liquid matrix material and/or a liquid matrix-precursor material, and in a third step the material of the matrix is solidified and/or polymerized and/or cross-linked. In accordance with the proposed invention prior to and/or during solidification and/or polymerization and/or cross-linking of the matrix material or the matrix precursor material, respectively, a magnetic field is applied so as to align the reinforcing particles in the matrix and this alignment is fixed in the matrix during and after the third step, wherein the non-spherical reinforcing particles preferably have a length (l) in one dimension of at least 0.5 μm and wherein the weight ratio of the nano-particles to the non-spherical reinforcing particles is below 0.25. | 02-28-2013 |
20130040350 | Process for the Direct Production of Fermentation Products from Biomasses in a Biofilm Reactor - A dense but oxygen permeable membrane separates the oxygen supply compartment from the fermentation compartment, which contains all microorganisms, a nutrient medium and the pretreated lignocellulose. The oxygen, necessary for the growth and the activity of the aerobic cellulolytic enzymes producing microorganisms is solely transported from the oxygen supply compartment through the membrane, which leads to an oxygen gradient within the biofilm growing on the membrane. The oxygen rich zone of the biofilm lies on the membrane whereas the biofilm further away from the membrane as well as the surrounding nutrient medium are oxygen depleted. In the aerobic biofilm the extra-cellular enzymes are produced in situ and are released into the nutrient medium where they hydrolyse the cellulose and hemicellulose into soluble monosugars, which are then converted to the desired fermentation product by suitable microorganisms in the anaerobic zones of the reactor. | 02-14-2013 |
20120321686 | Antifungal Material - The present invention relates to antifungal materials, particularly to nanoparticles comprising or consisting of a non-persistent inorganic support material such as Tricalciumphosphate (TCP) and copper as a dopant in the form of Cu | 12-20-2012 |
20120219596 | INJECTABLE FORMULATION FOR TREATMENT AND PROTECTION OF PATIENTS HAVING AN INFLAMMATORY REACTION OR AN ISCHEMIA-REPERFUSION EVENT - Compounds according to formula (I) are particularly suitable for the treatment and/or prevention of a medical condition involving hypoxic, anoxic and/or inflamed mammalian tissue. Furthermore, the invention relates to the use of said compounds for preparing a medicament and to pharmaceutical preparations comprising such compounds. The invention also relates to methods of treating or protecting patients having or being prone to develop a medical condition involving hypoxic, anoxic and/or inflamed mammalian tissue, the methods comprising administration of a therapeutically effective amount of such compounds | 08-30-2012 |
20120207737 | MEDICAL UTILITY OF GLYCAN-BINDING PROTEINS AND GLYCANS - The present invention relates to the use of glycan-binding polypeptides and glycans as a medicament, in particular for treating and/or preventing helminthic infections or an immune disease. Moreover, the present invention is directed to corresponding pharmaceutical compositions, food products and animal feed comprising isolated glycans and/or glycan-binding polypeptides. In addition, the present invention teaches methods for identifying anti-helminthic carbohydrate-binding polypeptides, for identifying helminthic glycan and gene targets involved in glycan-mediated toxicity, for identifying helminths susceptible to glycan-mediated toxicity, and for identifying anti-helminthic and anti-allergic substances. | 08-16-2012 |
20120164716 | BIOCHIP SENSOR - Small and extremely small molecules and ions or atoms may be detected with the novel device with exceptional sensitivity. The detection is implemented in a simple manner by the known acoustic resonator FBAR or by means of other technologies that measure the physical properties of the filled layer. The permeability of substances (e.g. active ingredients) through membranes such as cell membranes, lipid bilayers, and cell walls can be examined by combining a sensor with the reservoir and the membrane. | 06-28-2012 |
20120158380 | System And Method For Simulating Fluid Flow In A Fractured Reservoir - A method, system and computer program product are disclosed for simulating fluid flow in a fractured subterranean reservoir. A reservoir model representative of a fractured subterranean reservoir is provided. The reservoir model includes porous matrix control volumes and a network of fractures, which define fracture control volumes, overlying the porous matrix control volumes. A system of equations based on scale separation is constructed for fluid flow in the porous matrix control volumes and the fracture control volumes. The system of equations can include fracture equations having a pressure vector for each network of fractures that is split into an average pressure value and remainder pressure value. The system of equations based on scale separation is sequentially solved, such as by using an iterative Multi-Scale Finite Volume (MSFV) method. | 06-21-2012 |
20120148646 | RADIO-OPAQUE BIOACTIVE GLASS MATERIALS - Nanoparticulate material containing a matrix and embedded therein a radiopacifier are bioactive, show a high alkaline capacity and are radio-opaque. Compositions and formulations including such material are particularly useful in advanced dental applications, such as dental fillings and/or disinfection. | 06-14-2012 |
20120122959 | Targeting MicroRNAs for Metabolic Disorders - Provided herein are methods and compositions for the treatment of metabolic disorders. Also provided herein are methods and compositions for the reduction of blood glucose level, the reduction of gluceoneogenesis, the improvement of insulin resistance and the reduction of plasma cholesterol level. In certain embodiments, the methods comprise inhibiting the activity of miR-103. In certain embodiments, the methods comprise inhibiting the activity of miR-107. In certain embodiments, the activity of both miR-103 and miR-107 is inhibited. In certain embodiments, such methods comprise administering a compound comprising an oligonucleotide targeted to a microRNA. | 05-17-2012 |
20120076711 | AMINE CONTAINING FIBROUS STRUCTURE FOR ADSORPTION OF CO2 FROM ATMOSPHERIC AIR - A structure is disclosed containing a sorbent with amine groups that is capable of a reversible adsorption and desorption cycle for capturing CO | 03-29-2012 |
20120076164 | MICROWAVE CIRCUIT - A microwave circuit includes at least one inductive portion and at least one capacitive portion and having a resonance frequency, the microwave circuit including a material which acts as a dielectric for the capacitive portion, characterized in that the material acting as a dielectric includes an active region that is an electrically pumped semiconductor heterostructure having at least two energy levels whose energy separation is close to the resonance frequency of the microwave circuit. | 03-29-2012 |
20120043124 | ELECTRICAL DEVICE - The present invention relates to an electrical device comprising a substrate, a pair of electrodes arranged on the substrate and a functional layer arranged between the pair of electrodes, said functional layer comprising a functional domain being capable of transforming an external stimulus into an electrical signal or vice versa. The electrical device is characterized in that at least two conductive domains are dispersed in the functional layer. Said at least two conductive domains are separated from each other and are formed in each case by a particle or an agglomerate of particles of a conducting or semiconducting material having a higher electrical conductivity than the material of the functional domain. Each of the conductive domains form an electrically conductive path on the functional domain. | 02-23-2012 |
20110303460 | ROCK DRILLING IN GREAT DEPTHS BY THERMAL FRAGMENTATION USING HIGHLY EXOTHERMIC REACTIONS EVOLVING IN THE ENVIRONMENT OF A WATER-BASED DRILLING FLUID - A method and a device to thermally fragment rock for excavation of vertical and directional boreholes in rock formations, preferentially hard rock, using highly exothermic reactions. Exothermic reactions are initiated directly in the pressurized, aqueous environment of a water-based drilling fluid preferably above the critical pressure of water (221 bar). After reaction onset temperatures within the reaction zone exceed the critical temperature for water (374° C.) providing supercritical conditions, which favor the stabilization of the reaction, e.g. a supercritical hydrothermal flame. Since reactions can be run directly in a water-based drilling fluid, the method proposed here allows high density drilling action as in conventional rotary drilling. A part from the hot reaction zone of the proposed reaction can be brought directly to the rock surface in case of hard polycrystalline rock, where high temperatures are required. | 12-15-2011 |
20110297748 | METHOD AND PORTABLE APPARATUS FOR RECOGNIZING BAR CODES - A method for optical recording of a linear barcode pattern and determination of a symbol sequence as defined by the barcode pattern from a blurred raw image and includes the following steps: taking a raw image of the barcode pattern, preprocessing the raw image to generate a series of output patterns, comparing the output pattern with stored reference patterns, wherein the reference patterns correspond to blurred images of sharp nominal patterns and each reference pattern is provided with at least one symbol, determining for each of the output patterns the reference pattern which most closely resembles the output pattern outputting, transmitting or storing the symbols corresponding to the determined reference pattern and following the sequence of output patterns, as a symbol sequence. | 12-08-2011 |
20110291738 | JFET Series Connection - The invention relates to a switching device for switching a current between a first connection ( | 12-01-2011 |
20110144920 | METHOD, SYSTEM AND DEVICE FOR ENHANCING FLOW FIELD DATA - A method, system and device are described for generating high-resolution flow-field data from sparse measurement data by interpolating from a reference database of pre-computed, highly-resolved fluid dynamic simulation results, to generate a highly-resolved set of flow field data which correspond to the sparse measurements. In one embodiment, the method, system and device use Principal Component Analysis techniques to interpolate the multidimensional fluid flow data. Applications of the invention are, amongst others, in the field of biomedical diagnosis involving fluid dynamic modeling of biological fluid systems such as blood flow in an artery. | 06-16-2011 |
20110123183 | SPATIALLY ADAPTIVE PHOTOGRAPHIC FLASH UNIT - Using photographic flash for candid shots often results in an unevenly lit scene, in which objects in the back appear dark. A spatially adaptive photographic flash ( | 05-26-2011 |
20110123120 | METHOD AND SYSTEM FOR GENERATING A PICTORIAL REFERENCE DATABASE USING GEOGRAPHICAL INFORMATION - For generating a pictorial reference database from a plurality of digital images, distributed geographical sub-areas are defined (S | 05-26-2011 |
20110065605 | METHOD FOR BIOMARKER AND DRUG-TARGET DISCOVERY FOR PROSTATE CANCER DIAGNOSIS AND TREATMENT AS WELL AS BIOMARKER ASSAYS DETERMINED THEREWITH - The invention relates to a method for the determination of a cancer diagnostic/therapeutic biomarker assay and drug-targets including the following steps: (a) identification of potential candidate protein/peptide biomarkers and drug-targets based on the measurement of protein/peptide constituent concentrations in tissue sample proteomes as well as serum, plasma or any other derivatives of blood, or blood itself sample proteomes derived from healthy non-human mammalian individuals as well as from cancerous non-human mammalian individuals and qualitatively selecting as potential candidate protein/peptide biomarkers those which show a pronounced differential behaviour between healthy and cancerous sample proteomes; (b) optional verification of the potential candidate protein/peptide biomarkers as identified in step (a) by quantitative mass spectrometric measurement of the potential candidate protein biomarkers in serum, plasma or any other derivatives of blood, or blood itself sample proteomes derived from healthy non-human mammalian individuals as well as from cancerous non-human mammalian individuals and selecting as candidate protein/peptide biomarkers those which show a mass-spectrometrically measurable quantitative differential behaviour between healthy and cancerous sample proteomes; (c) validation of the candidate protein/peptide biomarkers as identified in step (a), or as optionally verified in step (b), by mass spectrometric measurement and/or antibody-based assays such as an Enzyme-Linked Immunosorbent Assay (ELISA) determination of the candidate protein biomarkers in serum, plasma or any other derivatives of blood, or blood itself sample proteomes derived from healthy human individuals as well as from cancerous human individuals and selecting as protein/peptide biomarkers those which show a mass-spectrometrically measurable and/or antibody-based assay detectable differential behaviour between healthy and cancerous sample proteomes; (d) application of statistical methods to uncover single or groups of protein/peptide biomarkers as validated in step (c) as signatures for the detection of patients with cancer. The invention furthermore relates to specific biomarker assays for the highly reliable diagnosis of cancer, specifically of localized or non-localized prostate cancer, using human serum, plasma or any other derivatives of blood, or blood itself. | 03-17-2011 |
20100264776 | WIRELESS RESONANT MAGNETIC ACUTATION FOR UNTETHERED MICROROBOTS - The invention concerns a novel magnetic actuator mechanism suitable for use on untethered microrobots. It relies on the interaction of magnetic bodies in an external magnetic field. By an oscillating field, the bodies are driven to oscillatory motion, and the energy stored in the oscillation is harnessed. The untethered wireless microactuator according to the invention comprises a mechanical system with at least two magnetic bodies resiliently connected to one another, wherein the mechanical system is capable of being oscillated, in particular driven to resonance, by an oscillating external magnetic field. The actuation system according to the invention comprises such a microrobot as well as a magnetic field generator with adjustable field direction and oscillation frequency. The actuation method comprises exciting two or more magnetic bodies with an oscillating magnetic field such that they perform mechanical oscillations, and harnessing this energy for propulsion of the device or to fulfill other tasks. | 10-21-2010 |
20100250737 | DETECTING AND CONTROLLING PEER-TO-PEER TRAFFIC - A method for communication management includes detecting addresses of peer nodes ( | 09-30-2010 |
20100214291 | COMPUTER SYSTEM AND METHOD FOR GENERATING A 3D GEOMETRIC MODEL - For generating a 3D geometric model ( | 08-26-2010 |
20100196440 | Implant Material - The present relates to the field of dental and bone surgery. In particular, the invention relates to fibrous pharmaceutical compositions; fibrous webs, yarns and woven fabrics of such pharmaceutical compositions; to implant material essentially consisting of fibrous pharmaceutical compositions; to the manufacturing and use of such fibers/webs/implant materials. | 08-05-2010 |
20100150980 | ANTIMICROBIAL MATERIAL - The present invention relates to nanoparticles containing a non-persistent support material and metallic silver particles on the surface of said support material as further specified in the description; to composites containing said nanoparticles; to the manufacture of said nanoparticles and composites and to the use of said nanoparticles and composites. | 06-17-2010 |
20100121110 | METHOD FOR THE BREAKDOWN OF LIGNIN - The invention describes a method for the direct production of molecules with a minimum molecular weight of 78 g/mol by the breakdown of lignin, lignin derivatives, lignin fragments, and/or lignin-containing substances or mixtures in the presence of at least one polyoxometallate and preferably in the presence of a radical scavenger in a liquid medium. | 05-13-2010 |
20100094605 | ITERATIVE MULTI-SCALE METHOD FOR FLOW IN POROUS MEDIA - Computer-implemented iterative multi-scale methods and systems are provided for handling simulation of complex, highly anisotropic, heterogeneous domains. A system and method can be configured to achieve simulation of structures where accurate localization assumptions do not exist. The iterative system and method smoothes the solution field by applying line relaxation in all spatial directions. The smoother is unconditionally stable and leads to sets of tri-diagonal linear systems that can be solved efficiently, such as by the Thomas algorithm. Furthermore, the iterative smoothing procedure, for the improvement of the localization assumptions, does not need to be applied in every time step of the computation. | 04-15-2010 |
20100078034 | IMMOBILIZING DEVICE FOR A PART OF A BODY - An immobilizing device for immobilizing a body part includes a bag which is filled with a granular material and is placed over the body part, an outer shell in which the bag is mounted and a hollow space formed between the outer shell and the bag for receiving pressured air in order to produce a force on the bag for immobilizing the body part. The device provides combined advantages over conventional devices, such as almost no absorption of x-rays, a perfect fit for every kind of body part, comfort for a patient, reusability, low cost, neutral smell, very light weight and easy application. | 04-01-2010 |
20100059449 | Carbon Coated Magnetic Nanoparticles and Their Use in Separation Processes - The invention relates to a process for separating a dispersed phase from a continuous phase comprising the steps of i) contacting said phases with an effective amount of nanoparticles; ii) applying a magnetic field gradient to the obtained system; iii) separating the obtained phases wherein said nanoparticles are of the core shell type, said core consists of a metal or alloy having soft magnetic properties and said shell contains a graphene layers which are optionally functionalized; to new nanoparticles and method of manufacturing such nanoparticles. | 03-11-2010 |
20100022857 | MAGNETICALLY CONTROLLED WIRELESS OPTICAL OXYGEN SENSOR FOR INTRAOCULAR MEASUREMENTS - A sensor for intraocular measurements moveable within at least one of an vitreous humor of an eye, an aqueous humor of an eye and an intraocular replacement medium. The sensor includes a magnetic body susceptible to magnetic fields and at least one sensor film. | 01-28-2010 |
20090306443 | Production of Saturated C2 to C5 Hydrocarbons - Catalytic methods for the production of saturated hydrocarbons with 2 to 5 carbon atoms per molecule by conversion of small hydrocarbon halides and/or hydrogenation of carbonaceous material are disclosed that result in high yield of saturated C2 to C5 hydrocarbons at reduced corrosion of the reactors and in good lifetime of the catalyst. The methods are performed in the presence of a Lewis acid comprising catalyst and in the absence of oxygen or oxygen containing compounds, whereby an upper limit of at most 50 parts per million mass of oxygen or oxygen containing compounds can be tolerated. | 12-10-2009 |
20090304114 | METHOD FOR DECODING DIGITAL INFORMATION ENCODED WITH A CHANNEL CODE - The performance of multiple-input multiple-output (MIMO) systems, employing coding with multiple antennas depends heavily on the demapper algorithm which is used for MIMO detection. Soft-output demappers lead to better bit error rate (BER) performance compared to hard-decision demappers, but have a higher implementation complexity. The algorithm, proposed in this paper, relies on low-complexity harddecision MIMO detection. The reliability information for the received bits used to compute log-likelihood ratios is based on an estimate of the average bit error rate which is for example derived from the corresponding channel state information only. The algorithm is applicable to any hard-decision MIMO detector. As an example, we describe the application of the scheme to a linear MMSE detector and to sphere decoding with early termination. | 12-10-2009 |
20090303574 | BROADBAND TERAHERTZ RADIATION GENERATION AND DETECTION SYSTEM AND METHOD - The invention relates to a broadband Terahertz (THz) radiation generation and detection system and method. THz radiation is generated by optical rectification of an ultrashort pump pulse of a first wavelength having a duration in the picosecond- or sub-picosecond range in a first nonlinear optical crystal. The THz radiation is detected by electro-optic sampling or another appropriate method of a probe beam having a second wavelength in a second nonlinear optical crystal. According to the invention, at least one of the following conditions is fulfilled: a) the first wavelength is different from the second wavelength; b) the material of the first nonlinear optical crystal is different from the material of the second nonlinear optical crystal. This makes it possible to choose for the generation and for the detection process—independent of one another—the combination of wavelengths and nonlinear material and possibly other features of the pump/probe pulses like polarization with the highest efficiency for generation and detection of Terahertz pulses, respectively. | 12-10-2009 |
20090261845 | ENANTIOSELECTIVE CAPACITIVE SENSOR - The present invention relates to an enantioselective capacitive sensor, its manufacture and use and to devices comprising such sensors. | 10-22-2009 |
20090184892 | DISPLAY DEVICE - A display device is formed from a plurality of modules ( | 07-23-2009 |
20090074798 | System and method for the production of recombinant glycosylated proteins in a prokaryotic host - A system and a method for the production of recombinant N-glycosylated target proteins. The system comprises a prokaryotic organism (e.g. | 03-19-2009 |
20090063106 | METHOD AND DEVICE FOR DECODING A SIGNAL OF MULTIPLE INPUT/MULTIPLE OUTPUT SYSTEM - The method for decoding a received signal in a multiple input/multiple output system uses QR-decomposition of the linear channel matrix, but then applies a non-Euclidean norm during tree traversal. Two separate hardware units, namely an MCU and a MEU, art provided for concurrent operation. The MCU determines a next child node, while the MEU determines next best parent nodes on the previously processed tree levels, which makes it possible to retrace the path to a next starting node without investing dedicated processing steps (e.g., cycles). On each tree level, the possible coordinates are grouped into several circular sets in the complex plane, and a series of decision boundaries is calculated for each set that allows a quick evaluation of the optimum coordinate in each set. | 03-05-2009 |
20080268246 | Methods and Devices for Flame Spray Pyrolysis - The present invention relates the manufacture of metal powders, non-oxidic ceramic powders and reduced metal oxide powders using an improved flame spray pyrolysis (“FSP”) process. The invention further relates to an apparatus specifically adapted to said process, to powders/naoncomposites obtained by said process and to the use of said powders/nanocompsites. | 10-30-2008 |