CHRISTIAN-ALBRECHTS-UNIVERSITAT ZU KIEL Patent applications |
Patent application number | Title | Published |
20140171620 | CILIARY NEUROTROPHIC FACTOR VARIANTS - Nucleic acid molecule selected from the group consisting of (a) a nucleic acid molecule having a nucleotide sequence shown in SEQ ID: NO 1, (b) a nucleic acid molecule which encodes a peptide having an amino acid sequence shown in SEQ ID: NO 2, (c) a nucleic acid molecule whose complementary strand hybridizes to a nucleic acid molecule according to (a) or (b) and which codes for a peptide which binds to ciliary neurotrophic factor receptor (CNTFR), the peptide binding with lower affinity than ciliary neurotrophic factor to the interleukin-6 receptor (IL-6R), (d) a nucleic acid molecule whose nucleotide sequence differs from the nucleotide sequence of a nucleic acid molecule according to (c) due to the degenerated genetic code, the codon at positions 82-84 of the nucleic acid molecule according to (a) coding for a non-positively charged amino acid, and the peptide at position 28 shown in SEQ ID: NO 2 having a non-positively charged amino acid residue. | 06-19-2014 |
20140140949 | TREATMENT OF OBESITY - The present invention relates generally to a method of increasing lipid oxidation in a mammal and to agents useful for same. More particularly, the present invention relates to a method of increasing lipid oxidation in a mammal by administering a ligand which interacts with the IL-6 receptor and signals via interaction with a gp130/LIF receptor heterodimer. In a related aspect, the present invention provides a method of increasing insulin sensitivity in a mammal. The method of present invention is useful, inter alia, in the treatment and/or prophylaxis of conditions characterised by unwanted lipid accumulation (such as obesity, obesity induced-metabolic disorders, type II diabetes, dyslipidemia, glucose intolerance, insulin resistance, obstructive sleep apnea, cardiovascular disease or non-alcoholic fatty liver disease) or inadequate insulin sensitivity. | 05-22-2014 |
20140125332 | MAGNETOSTRICTIVE LAYER SYSTEM - A magnetostrictive layer system is suggested comprising at least one layer sequence comprising an anti-ferromagnetic, (AFM), layer and a magnetostrictive, ferromagnetic, FM, layer arranged directly thereon, wherein the layer sequence has an associated exchange bias, EB, field, the EB-induced degree of magnetization of the FM layer in the absence of an external magnetic field being within a range between 85% and 100%, and the angle α | 05-08-2014 |
20140056947 | VIRUS TRAPS - Specific applications of particles and particle agglomerates with semiconductor surfaces are provided. The particles and particle agglomerates display a high affinity for viral particles, and may be used therapeutically and/or prophylactically to treat or prevent viral infections. The particles and particle agglomerates may also be used to remove viral particles from a surface or fluid, e.g., as an absorbent in a filter, applied to surfaces to render them virostatic, and as tool to handle viral particles, e.g., for research, diagnostic, or decontamination purposes. | 02-27-2014 |
20130028939 | CHIMERIC HUMAN BETA DEFENSINS - The invention relates to a nucleic acid molecule selected from the group comprising a) a nucleic acid molecule having one of the nucleotide sequences presented in SEQ ID:NO 4 to SEQ ID:NO 8, b) a nucleic acid molecule that codes for a peptide having one of the amino acid sequences presented in SEQ ID:NO 12 to SEQ ID:NO 16, c) a nucleic acid molecule, the complementary strand of which hybridizes to a nucleic acid molecule according to a) or b) and which codes for a peptide having antimicrobial activity, and d) a nucleic acid molecule, the nucleotide sequence of which deviates from the nucleotide sequence of a nucleic acid molecule according to c) because of the degenerated genetic code. | 01-31-2013 |
20120116725 | Method and Arrangement for Reconstructing the Source of an Electromagnetic Field - The disclosure relates to a method for reconstructing the source of an electromagnetic field. Firstly, a measurement space separate from the source is selected so that the measurement space is connected to the source via a magnetically homogeneous spatial region. Measured values of the electromagnetic field emitted by the source are recorded on the surface of the measurement space so that the electromagnetic field in the measurement space can be uniquely determined in the context of an error bound determined by the discreteness of the measured values. A mathematical model of the electromagnetic source is developed which has a multiplicity of unknowns, and a system of equations is set up that relates the unknowns of the model to the measured values. The system of equations is solved in order to determine the characteristics of the electromagnetic source. The disclosure also relates to an arrangement for carrying out the method. | 05-10-2012 |
20110012636 | MEASURING METHOD AND DEVICE FOR CHARACTERIZING A SEMICONDUCTOR COMPONENT - A measuring method for characterizing a semiconductor component ( | 01-20-2011 |
20100285229 | Method for Generating Oxidic Nanoparticles from a Material Forming Oxide Particles - A method for generating oxidic nanoparticles from a material forming oxide particles, comprising the steps of: preparation of an aqueous solution containing ions of the material forming the oxide particles, film evaporation of the solution at a temperature above 200° C., and skimming off the nanoparticles floating on the surface of the aqueous solution generated in the vicinity of the vapour film on film evaporation. A device for performing the method is also provided. | 11-11-2010 |