CEPHALON FRANCE Patent applications |
Patent application number | Title | Published |
20130123499 | Method for Purifying a Fused Pyrrolocarbazole Derivative - The present invention relates a method for purifying a fused pyrrolocarbazole compound known as 11-isobutyl-2-methyl-8-(2-pyrimidinylamino)-2,5,6,11,12,13-hexahydro-4Hindazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one using an acid complex thereof. The present invention also relates to a crystalline form of the acid complex. | 05-16-2013 |
20130066111 | Process for Enantioselective Synthesis of Single Enantiomers of Modafinil by Asymmetric Oxidation - The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of:
| 03-14-2013 |
20120252795 | ORAL LYSOPHILISATES CONTAINING PVP/VA - The present invention relates to novel oral pharmaceutical compositions in lyophilized form, in which the dissolution and the bioavailability of the active ingredient that they contain are improved. The compositions according to the invention comprise in particular a polyvinyl acetate/polyvinylpyrrolidone copolymer. The oral lyophilisates according to the invention are particularly suitable for the production of medicaments based on active ingredients which have low solubility or very low solubility in water or which are virtually insoluble in water. | 10-04-2012 |
20120245156 | ORAL LYOPHILIZED COMPOSITIONS - The present invention relates to a method for preparing an oral lyophilizate composition comprising:
| 09-27-2012 |
20120238551 | Substituted Phenoxypropylcycloamine Derivatives as Histamine-3 (H3) Receptor Ligands - The present invention provides compounds of formula I: | 09-20-2012 |
20120123161 | Process for Enantioselective Synthesis of Single Enantiomers of Modafinil by Asymmetric Oxidation - The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of:
| 05-17-2012 |
20120035133 | Lyophilization Cakes of Proteasome Inhibitors - Lyophilized cakes of proteasome inhibitors are described, as well as methods for their production and use. | 02-09-2012 |
20110229578 | MODAFINIL ORAL LYOPHILIZATE - The invention concerns an oral lyophilizate comprising modafinil particles having a median diameter of about 10 to about 1000 μm in association with an appropriate amount of at least one excipient selected from the group consisting of fatty acid esters of glycerol, cyclic oligosaccharides, sweeteners or mixtures thereof. | 09-22-2011 |
20110224436 | REGIOSELECTIVE REDUCTION OF FUSED PYRROLOCARBAZOLES-5,7-DIONES - The present invention relates to a method for regioselectively reducing the maleimide compounds of formula (I). The invention also relates to C | 09-15-2011 |
20110098505 | Process for Enantioselective Synthesis of Single Enantiomers of Thio-Substituted Arylmethanesulfinyl Derivatives by Asymmetric Oxidation - The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of:
| 04-28-2011 |
20100080829 | LYOPHILIZED PHARMACEUTICAL COMPOSITIONS AND METHODS OF MAKING AND USING SAME - The present invention relates to a new lyophilized pharmaceutical composition capable of adhering to oral mucosal tissue for an extended period of time for delivering active pharmaceutical ingredient through the oral mucosal tissue using transmucosal absorption. | 04-01-2010 |
20100048720 | Process for the Preparation of and Crystalline Forms of Optical Enantiomers of Modafinil - The invention relates to a polymorphic form of (−)-modafinil that produces a powder X-ray diffraction spectrum comprising intensity peaks corresponding to interplanar spacings of about 14.14, 10.66, 7.80 and 4.02 Å, and a process for the preparation thereof. | 02-25-2010 |
20100048719 | Process for the Preparation of and Crystalline Forms of Optical Enantiomers of Modafinil - The invention relates to a polymorphic form of (−)-modafinil that produces a powder X-ray diffraction spectrum comprising intensity peaks corresponding to interplanar spacings of about 12.31, 8.54, 7.27 and 3.62 Å, and a process for the preparation thereof. | 02-25-2010 |
20100048718 | Process for the Preparation of and Crystalline Forms of Optical Enantiomers of Modafinil - The invention relates to a polymorphic form of (−)-modafinil that produces a powder X-ray diffraction spectrum comprising intensity peaks corresponding to interplanar spacings of about 5.23, 5.03, 4.22 and 4.10 Å, and a process for the preparation thereof. | 02-25-2010 |
20100022653 | Process for the Preparation of and Crystalline Forms of Optical Enantiomers of Modafinil - The invention relates to a polymorphic form of (−)-modafinil that produces a powder X-ray diffraction spectrum comprising intensity peaks corresponding to interplanar spacings of about 8.54, 4.56, and 3.78 Å, and a process for the preparation thereof. | 01-28-2010 |
20090281193 | Process for the Preparation of and Crystalline Forms of Optical Enantiomers of Modafinil - The invention relates to a polymorphic form of (−)-modafinil that produces a powder X-ray diffraction spectrum comprising intensity peaks corresponding to interplanar spacings of about 9.45, 7.15, 5.13, 4.15 and 3.67 Å, and a process for the preparation thereof. | 11-12-2009 |
20090281192 | Process for the Preparation of and Crystalline Forms of Optical Enantiomers of Modafinil - The invention relates to a polymorphic form of (−)-modafinil that produces a powder X-ray diffraction spectrum comprising intensity peaks corresponding to interplanar spacings of about 12.38, 8.58, 7.34, 5.00 and 4.09 Å, and a process for the preparation thereof. | 11-12-2009 |
20090105241 | THIO-SUBSTITUTED TRICYCLIC AND BICYCLIC AROMATIC METHANESULFINYL DERIVATIVES - The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions of compounds of Formula (A): | 04-23-2009 |
20090042907 | Bicyclic aromatic sulfinyl derivatives - The present invention provides compounds of the structure: | 02-12-2009 |
20090018143 | Thio-substituted arylmethanesulfinyl derivatives - The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions of compounds of Formula (A): | 01-15-2009 |
20080214868 | PROCESS FOR ENANTIOSELECTIVE SYNTHESIS OF SINGLE ENANTIOMERS OF MODAFINIL BY ASYMMETRIC OXIDATION - The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of:
| 09-04-2008 |