Butamax Advanced Biofuels LLC Patent applications |
Patent application number | Title | Published |
20160138050 | YEAST WITH INCREASED BUTANOL TOLERANCE INVOLVING CELL WALL PROTEINS - Provided herein are recombinant yeast host cells and methods for their use for production of fermentation products from a pyruvate utilizing pathway. The yeast host cells provided herein comprise at least one genetic modification in a pyruvate decarboxylase gene and at least one genetic modification in an endogenous cell wall protein, which confers resistance to butanol and increased glucose utilization. | 05-19-2016 |
20150376096 | METHOD FOR PRODUCING BUTANOL USING EXTRACTIVE FERMENTATION - The invention relates to a method for producing butanol through microbial fermentation, in which the butanol product is removed by extraction into a water immiscible organic extractant composition during the fermentation. The invention also relates to a method for producing butanol through microbial fermentation, in which the butanol product is removed during the fermentation by extraction into a water-immiscible extractant composition comprising a first solvent having a butanol partition coefficient of at least 3, and a second solvent having a butanol partition coefficient, wherein the butanol partition coefficient of the first solvent is higher than the butanol partition coefficient of the second solvent. Optionally, the first solvent has a higher concentration of hydrogen bonding sites than the second solvent. The invention further relates to a composition including butanol in the water immiscible organic extractant composition described above. | 12-31-2015 |
20150291900 | Process for making isooctenes from aqueous isobutanol - The present invention relates to a catalytic process for making isooctenes using a reactant comprising isobutanol and water. The isooctenes so produced are useful for the production of fuel additives. | 10-15-2015 |
20150252389 | FERMENTIVE PRODUCTION OF FOUR CARBON ALCOHOLS - Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth of a recombinant bacterium expressing an isobutanol biosynthetic pathway. | 09-10-2015 |
20150247169 | FERMENTIVE PRODUCTION OF FOUR CARBON ALCOHOLS - Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth of a recombinant bacterium expressing an isobutanol biosynthetic pathway. | 09-03-2015 |
20150218595 | FERMENTATIVE PRODUCTION OF ALCOHOLS - The invention relates to the development of microorganisms capable of producing fermentation products via an engineered pathway in the microorganisms. The invention also relates to microorganisms with improved cell viability and methods to improve cell viability and cell productivity of a microorganism. | 08-06-2015 |
20150007488 | OXYGENATED GASOLINE COMPOSITION HAVING GOOD DRIVEABILITY PERFORMANCE - A method for producing a gasoline blend having a high concentration of a butanol isomer and having good cold start and warm-up driveability performance. | 01-08-2015 |
20140377824 | ALCOHOL DEHYDROGENASES (ADH) USEFUL FOR FERMENTIVE PRODUCTION OF LOWER ALKYL ALCOHOLS - The invention relates to suitable candidate ADH enzymes for production of lower alkyl alcohols including isobutanol. The invention also relates to recombinant host cells that comprise such ADH enzymes and methods for producing lower alkyl alcohols in the same. | 12-25-2014 |
20140363865 | SUPPLEMENTATION OF FATTY ACIDS FOR IMPROVING ALCOHOL PRODUCTIVITY - Fatty acids derived from biomass at a step in a fermentation process can be added to a fermentation medium comprising a recombinant microorganism that produces a product alcohol. At least one of growth rate and fermentable carbon consumption of the microorganism is greater in the presence of the fatty acids than the growth rate and the fermentable carbon consumption of the microorganism in the absence of the fatty acids. The addition of the fatty acids can increase glucose consumption, and can improve microorganism biomass production (cell growth/density) and growth rate, thereby reducing production time and increasing productivity of the fermentation process. | 12-11-2014 |
20140308735 | INCREASED PRODUCTION OF ISOBUTANOL IN YEAST WITH REDUCED MITOCHONDRIAL AMINO ACID BIOSYNTHESIS - Yeast cells with reduced activity of certain enzymes involved in branched chain amino acid biosynthesis in yeast mitochondria are described. Target enzymes include threonine deaminase, isopropylmalate synthase, and optionally branched chain amino acid transaminase. | 10-16-2014 |
20140303408 | METHOD FOR PRODUCTION OF BUTANOL USING EXTRACTIVE FERMENTATION - Provided herein are methods for recovering butanol from a fermentation medium. The methods comprise providing a fermentation medium comprising butanol, water, and a recombinant microorganism comprising a butanol biosynthetic pathway, wherein the recombinant microorganism produces butanol; contacting the fermentation medium with a water immiscible organic extractant composition comprising a dry solvent to form a butanol-containing organic phase and an aqueous phase; and recovering the butanol from the butanol-containing organic phase. | 10-09-2014 |
20140273130 | COMPETITIVE GROWTH AND/OR PRODUCTION ADVANTAGE FOR BUTANOLOGEN MICROORGANISM - Provided herein are recombinant yeast host cells and methods for their use for production of fermentation products. Host cells provided herein comprise a pyruvate-utilizing pathway and a competitive growth advantage over other microorganisms in solution. | 09-18-2014 |
20140273129 | GLYCEROL 3- PHOSPHATE DEHYDROGENASE FOR BUTANOL PRODUCTION - Provided herein are glycerol-3-phosphate dehydrogenase (GPD) enzymes with increased K | 09-18-2014 |
20140273127 | PROCESSES AND SYSTEMS FOR THE PRODUCTION OF ALCOHOLS - The present invention relates to processes and systems for the production of fermentative products such as ethanol and butanol. The present invention also provides methods for separating feed stream components for improved biomass processing productivity. | 09-18-2014 |
20140273116 | DHAD VARIANTS AND METHODS OF SCREENING - Methods of screening for dihydroxy-acid dehydratase (DHAD) variants that display increased DHAD activity are disclosed, along with DHAD variants identified by these methods. Such enzymes can result in increased production of compounds from DHAD requiring biosynthetic pathways. Also disclosed are isolated nucleic acids encoding the DHAD variants, recombinant host cells comprising the isolated nucleic acid molecules, and methods of producing butanol. | 09-18-2014 |
20140256020 | IN SITU EXPRESSION OF LIPASE FOR ENZYMATIC PRODUCTION OF ALCOHOL ESTERS DURING FERMENTATION - Disclosed herein are methods of producing alcohol esters during a fermentation by providing alcohol-producing microorganisms which further comprise an engineered polynucleotide encoding a polypeptide having lipase activity. | 09-11-2014 |
20140234929 | PROCESSES AND SYSTEMS FOR ALCOHOL PRODUCTION AND RECOVERY - The present invention relates to processes for recovering butanol produced in a fermentative process using, for example, an ethanol production plant which has been reversibly-retrofitted for butanol production, that is, the ethanol production plant may be converted for butanol production, but can also revert to an ethanol production. The present invention also relates to processes for recovering butanol produced in a fermentative process in a butanol production plant that may be converted to ethanol production plant. | 08-21-2014 |
20140186911 | RECOMBINANT HOST CELLS AND METHODS FOR PRODUCING BUTANOL - Provided herein are recombinant yeast cells comprising a deletion or disruption in an endogenous gene encoding Amn1 and a heterologous gene encoding Amn1. Also provided are recombinant yeast cells comprising a heterologous gene encoding Amn1 and an engineered butanol biosynthetic pathway. Further provided are methods of producing isobutanol comprising providing the recombinant yeast cells described herein and culturing the recombinant yeast cells under conditions wherein isobutanol is produced. | 07-03-2014 |
20140178529 | ENZYMATIC PRODUCTION OF ALCOHOL ESTERS FOR RECOVERY OF DIOLS PRODUCED BY FERMENTATION - Diols produced in fermentation are processed in broth by esterification of the product diol with a carboxylic acid (e.g., fatty acid) and a catalyst (e.g., lipase) capable of esterifying the product diol, such as 1,3-propanediol, with the carboxylic acid to form the diol esters. The diol esters can be extracted from the broth, and the product diol recovered from the diol esters. The carboxylic acid can also serve as an extractant for removal of the diol esters from the fermentation medium. | 06-26-2014 |
20140170732 | Butanol Dehydrogenase Enzyme from the Bacterium Achromobacter xylosoxidans - From a bacterial strain isolated from an environmental sample, after enrichment in medium containing 1-butanol as the carbon source, a new enzyme with butanol dehydrogenase activity was identified. The enzyme can convert butyraldehyde to 1-butanol, isobutyraldehyde to isobutanol, as well as 2-butanone to 2-butanol and thus is useful for biosynthesis of butanol in recombinant microbial hosts producing these substrates. The encoding gene, named sadB, was isolated from the strain identified as an isolate of | 06-19-2014 |
20140162344 | IN SITU EXPRESSION OF LIPASE FOR ENZYMATIC PRODUCTION OF ALCOHOL ESTERS DURING FERMENTATION - Disclosed herein are methods of producing alcohol esters during a fermentation by providing alcohol-producing microorganisms which further comprise an engineered polynucleotide encoding a polypeptide having lipase activity. | 06-12-2014 |
20140162333 | Enhanced Pyruvate to Acetolactate Conversion in Yeast - A high flux in conversion of pyruvate to acetolactate was achieved in yeast through expression of acetolactate synthase in the cytosol in conjunction with reduction in pyruvate decarboxylase activity. Additional manipulations to improve flux to acetolactate are reduced pyruvate dehydrogenase activity and reduced glycerol-3-phosphate dehydrogenase activity. Production of compounds having acetolactate as an upstream intermediate benefit from the increased conversion of pruvate to acetolactate in the described strains. | 06-12-2014 |
20140142352 | BUTANOL PURIFICATION - Provided herein are processes for adjusting a fermentation medium to reduce the activity of one or more carboxylic acids. The processes comprise (a) providing a recombinant microorganism comprising an engineered butanol biosynthetic pathway, (b) contacting the recombinant microorganism with a fermentation medium whereby butanol is produced and wherein the fermentation medium comprises one or more carboxylic acids, and (c) adjusting the fermentation medium to reduce the activity of the one or more carboxylic acids. Also provided are processes for reducing the activity of one or more carboxylic acids in a feed. The processes comprise (a) providing a feed from a fermentation vessel, wherein the feed comprises a composition produced by a recombinant microorganism comprising an engineered butanol biosynthetic pathway, wherein the composition comprises butanol, water, and one or more carboxylic acids; and (b) adjusting the feed, wherein adjusting the feed reduces the activity of the one or more carboxylic acids. | 05-22-2014 |
20140109467 | Reduced RVP Oxygenated Gasoline Composition and Method - Compositions of oxygenated gasolines are disclosed that have reduced vapor pressure compared to those containing a single oxygenate and no RVP reducing compound. Such compositions can be formed at a refinery or at a terminal. Methods of reducing vapor pressure of an oxygenated gasoline are disclosed and methods of reducing vapor pressure constraints upon a refinery in the production of oxygenated gasoline are disclosed. Fundamental properties of RVP reducing compounds are disclosed including IR spectrum analysis. Processes and methods for blending and distributing these fuels are also disclosed. | 04-24-2014 |
20140106419 | PROCESSES AND SYSTEMS FOR THE PRODUCTION OF FERMENTATION PRODUCTS - The present invention relates to processes and systems for the production of fermentation products such as alcohols. The present invention also provides methods for separating feed stream components for improved biomass processing and productivity. | 04-17-2014 |
20140099688 | PROCESS TO REMOVE PRODUCT ALCOHOL FROM A FERMENTATION BY VAPORIZATION UNDER VACUUM - A fermentation liquid feed including water and a product alcohol and optionally CO | 04-10-2014 |
20140093931 | PRODUCTION OF FERMENTATION PRODUCTS - The invention relates to processes for the production of fermentation products such as alcohols including ethanol and butanol, and the development of microorganisms capable of producing fermentation products via an engineered pathway in the microorganisms. | 04-03-2014 |
20140080189 | Method for Producing Butanol using Extractive Fermentation with Electrolyte Addition - A method for producing butanol through microbial fermentation, in which the butanol product is removed during the fermentation by extraction into a water-immiscible organic extractant in the presence of at least one electrolyte at a concentration at least sufficient to increase the butanol partition coefficient relative to that in the presence of the salt concentration of the basal fermentation medium, is provided. The electrolyte may comprise a salt which dissociates in the fermentation medium, or in the aqueous phase of a biphasic fermentation medium, to form free ions. Also provided is a method and composition for recovering butanol from a fermentation medium. | 03-20-2014 |
20140073021 | PROCESSES AND SYSTEMS FOR THE PRODUCTION OF FERMENTATION PRODUCTS - The present invention relates to the production of fermentation products such as alcohols including ethanol and butanol, and processes employing in situ product removal methods. | 03-13-2014 |
20140051133 | KETOL-ACID REDUCTOISOMERASE ENZYMES AND METHODS OF USE - Provided herein are polypeptides having ketol-aid reductoisomerase activity as well as microbial host cells comprising such polypeptides. Polypeptides provided herein may be used in biosynthetic pathways, including, but not limited to, isobutanol biosynthetic pathways. | 02-20-2014 |
20140024094 | INCREASED PRODUCTION OF ISOBUTANOL IN YEAST WITH REDUCED MITOCHONDRIAL AMINO ACID BIOSYNTHESIS - Yeast cells with reduced activity of certain enzymes involved in branched chain amino acid biosynthesis in yeast mitochondria are described. Target enzymes include threonine deaminase, isopropylmalate synthase, and optionally branched chain amino acid transaminase. | 01-23-2014 |
20140018581 | Process to Remove Product Alcohol from a Fermentation by Vaporization under Vacuum - A fermentation liquid feed including water and a product alcohol and optionally CO | 01-16-2014 |
20130316414 | ENHANCED PYRUVATE TO 2,3-BUTANEDIOL CONVERSION IN LACTIC ACID BACTERIA - A high flux of metabolites from pyruvate to 2,3-butanediol in | 11-28-2013 |
20130309738 | Processes and Systems for Alcohol Production and Recovery - The present invention relates to processes for recovering butanol produced in a fermentative process using, for example, an ethanol production plant which has been reversibly-retrofitted for butanol production, that is, the ethanol production plant may be converted for butanol production, but can also revert to an ethanol production. The present invention also relates to processes for recovering butanol produced in a fermentative process in a butanol production plant that may be converted to ethanol production plant. | 11-21-2013 |
20130247450 | Gasoline Deposit Control Additive Compositions - A gasoline deposit control additive composition for use in a fuel comprising from about 70 to about 95 volume percent of hydrocarbons in the gasoline boiling range and from about 5 to about 30 volume percent of at least one alcohol, comprising the imine or tertiary amine product of the reaction between (a) at least one aldehyde or ketone or mixture thereof having the formula R | 09-26-2013 |
20130171706 | Fermentive Production of Four Carbon Alcohols - Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth of a recombinant bacterium expressing an isobutanol biosynthetic pathway. | 07-04-2013 |
20110162953 | RECOVERY OF BUTANOL FROM A MIXTURE OF BUTANOL, WATER, AND AN ORGANIC EXTRACTANT - A process for recovering butanol from a mixture comprising a water-immiscible organic extractant, water, butanol, and optionally a non-condensable gas, is provided. The butanol is selected from 1-butanol, isobutanol, and mixtures thereof. An overhead stream from a first distillation column is decanted into two liquid phases. The wet butanol phase is returned to the first distillation column as reflux. A bottom stream from the first distillation column is refined in a second distillation column to obtain a second overhead stream comprising butanol and a second bottoms stream comprising the extractant. The extractant comprises at least one solvent selected from the group consisting of C | 07-07-2011 |