Board of Trustees of the Leland Stanford Junior University Patent applications |
Patent application number | Title | Published |
20150174150 | Compositions and Methods for Treating Alzheimer's Disease and Other Tauopathies - Compounds, pharmaceutical compositions, and methods of using such compounds and compositions to treat or prevent Alzheimer's disease and related tauopathies through the inhibition of USP-9X and/or enhancement of SCF(β-TrCP). | 06-25-2015 |
20140231620 | IMAGE SENSOR AND IMAGING METHOD WITH SINGLE SHOT COMPRESSED SENSING - A CMOS image sensor includes a plurality of pixel elements arranged in a two-dimensional array, analog signal multiplexers, over-sampling A/D converters and an activation code generator. The sensor is configured to construct an image by using less number of A/D conversions, thereby reducing the power consumption of the sensor. The activation code generator generates a bit stream of random binary sequences which determine which A/D converter is activated. The image sensor offers digitally compressed data, the number of which is significantly less than the total number of pixels. Further, the image sensor not only reduces the power consumption of the A/D converters (by reducing the number of A/D conversions) but also reduces the I/O power consumption. An original image focused on the sensor is recovered from the compressed data by using principles of compressed sensing. | 08-21-2014 |
20140161843 | Dynamic Macropore Formation Using Multiple Porogens - Macroporous 3-D tissue engineering scaffold are manufactured by contacting an article comprising multiple distinct macroparticulate porogens distributed within a polymer scaffold, wherein the porogens are selectively and sequentially dissolvable by corresponding biocompatible stimuli. | 06-12-2014 |
20140088479 | FOOT PLATFORM - The therapeutic system of the preferred embodiments includes a foot platform having a lateral segment and a medial segment. The foot platform is coupled to the foot of the patient and supports the body force of the patient. The foot platform functions to move the foot from an equilibrium position to an activated position. The transition of the foot between equilibrium position and activated position, preferably occurs substantially instantaneously once the foot platform supports greater than substantially half of the body force. | 03-27-2014 |
20140046026 | SUPERAGONISTS AND ANTAGONISTS OF INTERLEUKIN-2 - Novel human interleukin-2 (IL-2) muteins or variants thereof, and nucleic acid molecules and variants thereof are provided. Methods for producing these muteins as well as methods for stimulating the immune system of an animal are also disclosed. In addition, the invention provides recombinant expression vectors comprising the nucleic acid molecules of this invention and host cells into which expression vectors have been introduced. Pharmaceutical compositions are included comprising a therapeutically effective amount of a human IL-2 mutein of the invention and a pharmaceutically acceptable carrier. The IL-2 muteins can be used in pharmaceutical compositions for use in treatment of cancer and in stimulating the immune response. | 02-13-2014 |
20130195358 | METHOD AND APPARATUS FOR ENHANCING VISUAL SEARCH - Various methods are described for improving the compression of location information during a visual search. One example method may comprise identifying one or more features of a source query image for a visual search. The method may further comprise generating a histogram map comprising one or more histogram bins, wherein the histogram map represents the location of the one or more features of the source query image. Additionally, the method may comprise generating a context for at least one of the one or more histogram bins, wherein the context comprises a first context value based on information related to one or more neighboring bins located a first distance from the respective histogram bin and a second context value based on information related to one or more neighboring bins located a second distance from the respective histogram bin. Similar and related methods, apparatuses, and computer program products are also provided. | 08-01-2013 |
20120277159 | METHODS FOR TREATING DEPRESSION USING NCAM PEPTIDE MIMETICS - The present application relates to the treatment and diagnosis of mood disorders, including bipolar disorder, major depression disorder and schizophrenia. The invention provides novel diagnostic markers and assays, as well as research tools for the development and discovery of agents and compounds which are useful for treating patients who suffer from mental illness. | 11-01-2012 |
20120077708 | BETA-2 MICROGLOBULIN AS A BIOMARKER FOR PERIPHERAL ARTERY DISEASE - The present invention provides β2 microglobulin as a biomarker for qualifying or assessing peripheral artery disease in a subject. | 03-29-2012 |
20110313681 | BIOMARKERS FOR PERIPHERAL ARTERY DISEASE - This invention provides biomarkers whose concentrations in blood plasma are associated with the presence or absence of PAD in the patient from whom the plasma sample is taken. The invention also provides biomarkers for distinguishing between PAD patients who are long claudicators and PAD patients who are not. In addition, the invention provides methods for identifying additional biomarkers, methods for detecting the biomarkers in patients, and methods for identifying agents, including pharmaceutical agents, which interact with the biomarkers and are useful for preventing or treating PAD in patients. | 12-22-2011 |
20110275575 | PEPTIDE INHIBITORS OF PROTEIN KINASE C - PKC V5 isozyme-specific peptides are described. The sequences and compositions comprising the sequences are useful for treating disease states associated with the PKC isozyme from which they are respectively derived. Methods of treatment, pharmaceutical formulations and methods of identifying compounds that mimic the activity of the peptides are also described. | 11-10-2011 |
20110014610 | COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING NEUROPSYCHIATRIC DISORDERS - The present invention provides methods for diagnosing mental disorders (e.g., psychotic disorders such as schizophrenia and mood disorders such as major depression disorder and bipolar disorder). The invention also provides methods of identifying modulators of such mental disorders as well as methods of using these modulators to treat patients suffering from such mental disorders. | 01-20-2011 |
20100152249 | COMPOSITONS AND METHOD FOR TREATMENT OF MOOD AND COGNITIVE IMPAIRMENTS - Compositions, manufacture, and methods for diagnosis and treatment of subjects exhibiting mood disorders and/or being at risk of cognitive impairment. | 06-17-2010 |
20100069464 | COMPOSITIONS AND METHODS FOR MODULATING ACTIVITY OF CAPPED SMALL RNAS - Compositions and methods for modulating transcription by RNA polymerases are described. | 03-18-2010 |
20100048482 | COMPOSITIONS AND METHODS FOR MODULATING EPSILON PROTEIN KINASE C-MEDIATED CYTOPROTECTION - Compositions and methods for reducing ischemic cell damage and treating mitochondrial disorders using therapeutic agents derived from the V2 domain of epsilon protein kinase C (PKC) are described. | 02-25-2010 |