Board of Supervisors of Louisiana State University and Agricultural and Mechanical College Patent applications |
Patent application number | Title | Published |
20160128363 | Palatable Foods for a Methionine-Restricted Diet - A method is disclosed for making palatable methionine-restricted foods, to deliver a methionine-restricted diet to human or veterinary patients. A protein or a food product containing protein is partially oxidized, preferably with ozone, to oxidize nearly all of the methionine and cysteine. After oxidation, tryptophan and lysine are optionally added back since they tend to be oxidized also. Optionally, a small amount of methionine is also added back so that the final methionine is within a preferred range of about 0.85 to about 1.8 gram methionine per 100 gram total protein, preferably about 1.2 gram per 100 gram total protein. | 05-12-2016 |
20160125104 | APPARATUSES, SYSTEMS AND METHODS FOR PERFORMING REMOTE REAL-TIME EXPERIMENTS - Embodiments of the present invention include apparatuses and methods for performing remote experiments in real-time. The method includes sending requests to perform remote experiments for a desired configuration to a first and second facility. The desired configuration may include a first and second configuration. The method includes running a first remote experiment in real-time at the first facility to obtain a first output variable. The first facility may include the first configuration with a first input variable. The method includes simultaneously running a second remote experiment in real-time at a second facility to obtain a second output variable. The second facility may include the second configuration with a second input variable. The first output variable may be set as the second input variable to mimic the desired configuration. The method includes obtaining experimental results of the desired configuration via the first and second input and output variables. | 05-05-2016 |
20160102126 | Novel Peptides Involved in Energy Homeostasis - The expression of a mRNA encoding a putative 76 amino acid, secreted protein (“Enho1”) was found to negatively correlate with fasting triglyceride and cholesterol levels. A recombinant adenovirus was used to increase the expression of Enho1 mRNA in two mouse models of obesity, KK-A | 04-14-2016 |
20160097075 | HIGH THROUGHPUT ASSAY FOR MONITORING AMP PRODUCTION AND AMINOACYL-tRNA SYNTHETASE ACTIVITY - A method of conducting an enzymatic reaction assay involving adenosine 5′-monophosphate (AMP) comprising the steps of reacting one or more compounds and producing AMP, deaminating the AMP to produce IMP, and oxidating the IMP by NAD+ to produce XMP and NADH. | 04-07-2016 |
20160089673 | HYBRID LINEAR ACTUATOR CONTROLLED HYDRAULIC CELL STRETCHING - A hydraulic cell stretching device comprising a source of variable pressured hydraulic fluid hydraulically coupled to a flexing chamber. The flexing chamber has at least one cell well. The cell well has a membrane subjected to the variable pressured hydraulic fluid. | 03-31-2016 |
20160068536 | Antimicrobial Monomers and Polymers, and Their Use in Dental Devices - Antimicrobial compounds are provided that are polymerizable. The compounds include monomers with antimicrobial properties. The compounds have cross-linking properties and are hydrolytically stable. The compounds may be utilized in dental and/or medical applications, including dental composites, dentures, bonding agents, sealants, resins and medical devices. | 03-10-2016 |
20160067316 | Selective Sensitization of Cancer Cells to, and Selective Protection of Non-Cancer Cells from Genotoxic Therapies - Compositions and methods are disclosed that employ Tousled-like kinase to selectively protect normal tissues from the adverse effects of radiation therapy, genotoxic chemotherapy and the like without protecting cancer tissues; or to sensitize cancer cells to such cancer therapies without similarly sensitizing normal tissues; or both protect normal cells and sensitize cancer cells. The compositions and methods may be used as a complementary therapy to selectively reduce adverse effects of the principal therapy (radiation therapy or chemotherapy) in normal tissues, with minimal impact on the antitumor effects of the principal therapy. | 03-10-2016 |
20160051492 | CONTINUOUS LOCAL SLOW-RELEASE OF THERAPEUTICS FOR HEAD AND NECK PROBLEMS AND UPPER AERODIGESTIVE DISORDERS - The invention features formulations for the local delivery of therapeutically effective doses of curcumin to treat head and neck disorders and upper aerodigestive disorders. Also disclosed are use of the formulations for delivery of other phytochemicals, or the combination of phytochemicals for the treatment of said disorders. Furthermore, these formulations can be used to deliver the recommended daily allowance of vitamins and/or minerals to children or adults. | 02-25-2016 |
20160025711 | FLUORESCENT MARKERS AND METHODS FOR IMAGING DISEASES - Methods and fluorescent probes that detect the presence of diseased cells such as cancer. The fluorescent probes are cloaked, turn-on probes having the fluorescence reporter released only in the presence of enzymes typically over-expressed in diseased and cancerous tissue. Probes include a fluorescent napthalimide reporter with a quinoidal moiety cloak. | 01-28-2016 |
20160017462 | MULTICALORIC MnNiSi ALLOYS - A multicaloric alloy material combines two isostructural compounds, the first compound being MnNiSi and the second compound being either MnFeGe or CoFeGe, each such compound having extremely different magnetic and thermo-structural properties. The resulting alloy material (MnNiSi) | 01-21-2016 |
20150363345 | APPARATUSES AND METHODS OF INCREASING OFF-CHIP BANDWIDTH - Embodiments of the present invention include methods for increasing off-chip bandwidth. The method includes designing a circuit of switchable pins, replacing a portion of allocated pins of a processor with switchable pins, connecting the processor to a memory interface configured to switch the switchable pins between a power mode and a signal mode, providing a metric configured to identify which of the power mode and the signal mode is most beneficial during 1 millisecond intervals, and switching the switchable pins to signal mode during intervals where the signal mode provides more benefit than the power mode. | 12-17-2015 |
20150344902 | Resistance to Acetohydroxyacid Synthase-Inhibiting Herbicides - Nucleotide sequences are disclosed that may be used to impart herbicide resistance to green plants. The sources of novel herbicide resistance were originally isolated in mutant rice plants. The sequences impart pre-emergence resistance, post-emergence resistance, or both pre-emergence resistance and post-emergence resistance to multiple herbicides. To date, resistance has been demonstrated against at least the following herbicides: imazethapyr, imazapic, imazapyr, imazamox, sulfometuron methyl, imazaquin, chlorimuron ethyl, metsulfuron methyl, rimsulfuron, thifensulfuron methyl, pyrithiobac sodium, tribenuron methyl, and nicosulfuron. Green plants transformed with these sequences are resistant to these herbicides and to derivatives of these herbicides, and to at least some of the other herbicides that normally inhibit acetohydroxyacid synthase (AHAS), particularly imidazolinone and sulfonylurea herbicides. | 12-03-2015 |
20150335249 | CONTACT-TYPE ENDOSCOPE SERS PROBE, AND RELATED METHODS - A contact-type endoscope surface enhanced Raman scattering (SERS) probe includes a gradient-index (GRIN) lens, a transparent substrate adhered to the GRIN lens, and a rough metallic layer adhered to an opposite side of the transparent substrate from the GRIN lens. The GRIN lens focuses light from a Raman spectrometer onto the rough metallic layer, and the rough metallic layer is positioned at the distal end of the contact-type endoscope SERS probe. | 11-26-2015 |
20150300019 | Sandwich Panel with a Ductile Hybrid Core Comprising Tubular Reinforcements - A hybrid core comprising a matrix and tubular structural reinforcements, such as a ductile matrix core reinforced with ductile hollow tubes, as well as panels which comprise such hybrid core. Embodiments of the invention manifest resistance to both interfacial debonding and ballistic penetration. | 10-22-2015 |
20150299954 | Nano-sized Bagasse Fiber - A new composition of nanosized bagasse fibers has been made by a method which reduces the sugarcane bagasse fibers to nano-sized particles while retaining the natural components of the bagasse. The resulting bagasse particles were shown to be effective as a nutritional supplement in a mouse model to aid in glucose control and body weight. Using the bagasse nanofibers, the addition of 5 to 10% fiber did not change the color or texture of food products. Moreover, the bagasse powder has a natural color and absorbs color evenly so that it could be used as a natural foundation material for cosmetic products. | 10-22-2015 |
20150299412 | Thiol Acrylate Nanocomposite Foams - Thiol-acrylate copolymers are disclosed that are useful, for example, as injectable biomaterials to provide both mechanical support and biological cues to stimulate bone regrowth. Composites can be formed, for example incorporating hydroxyapatite crystal inclusions into the copolymer. In one embodiment, the composite is gas-foamed with a blowing agent during or before cure to form a porous, interconnected scaffold. The synthesis employs an amine-catalyzed Michael addition co-polymerization of a poly-thiol with a poly-acrylate. The catalyst is an in situ catalyst, such as a tertiary amine moiety that is covalently bonded to one of the reactants, preferably to the poly-acrylate. The materials can rapidly co-polymerize in vivo or in vitro via catalysis by the “attached” in situ tertiary amine groups. | 10-22-2015 |
20150216126 | Herbicide Resistant Rice - Rice plants are disclosed with multiple sources of resistance to herbicides that normally inhibit a plant's acetohydroxyacid synthase (AHAS) enzyme. Besides controlling red rice, many AHAS-inhibiting herbicides also effectively control other weeds that are common in rice fields. Several of these herbicides have residual activity, so that one treatment can control both existing weeds and weeds that sprout later. With effective residual activity against red rice and other weeds, rice producers now have a weed control system superior to those that are currently available commercially. | 08-06-2015 |
20150210998 | METHODS OF MODULATING UBIQUITIN LIGASE ACTIVITY - Methods are provided for modulating the activity of multimeric ubiquitin-protein E3 ligases including, but not limited to, E6AP ligase activities. The methods reduce the level of oligomer formation such as homotrimeric E6AP ligase to reduce the enzyme activity. Alternatively, agents are provided that can promote the association of the ligase monomers, thereby increasing the ligase activity. Accordingly, novel therapeutic strategies are provided that are useful for the treatment of pathologies resulting from mutations in the genes encoding the ligases and which adversely increase or decrease a ubiquitination reaction. | 07-30-2015 |
20150174507 | Device for Degassing Liquids - A degassing chamber is disclosed, adapted for the efficient removal of entrained gases from liquids. In a preferred embodiment the degassing chamber is combined with and works in conjunction with a sedimentation tank to provide an efficient clarification station. The combined clarification station can have a “footprint” the same size as, or only slightly larger than, the footprint of the sedimentation tank alone. The degassing chamber is well-suited for retrofitting, and can easily be combined with most types of solid-liquid sedimentation tanks that are currently used in the industry. | 06-25-2015 |
20150126712 | METHODS OF EXTRACTING CHEMICAL COMPOUNDS FROM ORGANISMS WITH RESISTANT CELL WALLS - A method is provided for extraction of chemical compounds from an organism having a cell wall that includes adding nanomaterials, which may be at least one of metallic nanofibers, silica nanofibers, carbon nanofibers and metal doped silica and carbon nanofibers, wherein the nanofibers are generally doped with silver but may also include non-metallic nanofibers doped with metals other than silver, to the organism. | 05-07-2015 |
20150110862 | Sweet Gum Fruit Extract as a Therapeutic Agent - Sweet gum ( | 04-23-2015 |
20150099642 | METHODS AND DEVICES FOR DNA SEQUENCING AND MOLECULAR DIAGNOSTICS - The present invention is directed to methods for capturing, amplifying and identifying one or more of a plurality of target nucleotide sequences in a sample. The present invention is further directed to a device comprising a solid support having a plurality of wells or pillars and a plurality of oligonucleotides attached to the wells or pillars. Other aspects of the invention are directed to methods of making such devices. | 04-09-2015 |
20150096074 | Rice Cultivar Designated 'CL151' - A novel rice cultivar, designated ‘CL151,’ is disclosed. The invention relates to the seeds of rice cultivar ‘CL151,’ to the plants of rice ‘CL151,’ and to methods for producing a rice plant produced by crossing the cultivar ‘CL151’ with itself or another rice variety, and to single gene conversions of such plants. The invention further relates to hybrid rice seeds and plants produced by crossing the cultivar ‘CL151’ with another rice cultivar. The invention further relates to other derivatives of the cultivar ‘CL151.’ | 04-02-2015 |
20150080327 | Targeted Osmotic Lysis of Cancer Cells - A targeted osmotic lysis (TOL) of tumor cells that over-express voltage-gated sodium channels (VGSCs) has been developed that uses a combined therapy of a drug that blocks sodium, potassium-adenosine triphosphatase (Na | 03-19-2015 |
20140370422 | Nanoparticles, Nanosponges, Methods of Synthesis, and Methods of Use - We disclose novel metallic nanoparticles coated with a thin protective carbon shell, and three-dimensional nano-metallic sponges; methods of preparation of the nanoparticles; and uses for these novel materials, including wood preservation, strengthening of polymer and fiber/polymer building materials, and catalysis. | 12-18-2014 |
20140342402 | Stabilizing RNA by Incorporating Chain-Terminating Nucleosides at the 3'-Terminus - A method is disclosed for stabilizing histone stem-loop-containing mRNA by the addition of a chain-terminating nucleoside. The novel, synthetic mRNA contains a 3′ histone stem-loop sequence. At the 3′ end of the mRNA a chain-terminating nucleoside is incorporated, for example 3′-deoxyadenosine (cordycepin). The chain-terminating nucleoside blocks the addition of a 3′-terminal oligo(U) sequence to the mRNA containing the histone stem-loop. When the 3′-terminal oligo(U) sequence cannot be added, degradation of the mRNA is retarded. The mRNA then remains available to the translational machinery for a longer time, resulting in higher levels of protein synthesis. | 11-20-2014 |
20140331897 | Wet Process for Recycling Asphalt Shingle in Asphalt Binder - A new method is disclosed for recycling waste asphalt shingles in hot mix asphalt, i.e. asphalt pavement construction. Ground asphalt shingles are treated as a binder component instead of as an aggregate component. The recycled asphalt shingles that are blended with virgin binder in a wet process act both as a partial binder replacement and as a binder extender due to the presence of fillers, rubber, and fibers in the processed material. | 11-13-2014 |
20140327211 | COOLED SEAL - Seals having incorporated heat pipes are disclosed relating to pumps and other comparable sealing equipment that may include a seal face, a cavity, a wicking material within the cavity, and a working fluid within the cavity. The seals may be used as a pump seal rings and in other applications having comparable heat transfer requirements. | 11-06-2014 |
20140303287 | Self-Healing Composite of Thermoset Polymer and Programmed Super Contraction Fibers - A composition comprising thermoset polymer, shape memory polymer to facilitate macro scale damage closure, and a means for molecular scale healing is disclosed; the composition has the ability to resolve structural defects by a bio-mimetic close-then heal process. In use, the shape memory polymer serves to bring surfaces of a structural defect into approximation, whereafter use of the means for molecular scale healing allowed for movement of the healing means into the defect and thus obtain molecular scale healing. The means for molecular scale healing can be a thermoplastic such as fibers, particles or spheres which are used by heating to a level at or above the thermoplastic's melting point, then cooling of the composition below the melting temperature of the thermoplastic. Compositions of the invention have the ability to not only close macroscopic defects, but also to do so repeatedly even if another wound/damage occurs in a previously healed/repaired area. | 10-09-2014 |
20140299018 | Wet Process for Recycling Asphalt Shingle in Asphalt Binder for Asphalt Paving Applications - A method is disclosed for recycling asphalt roofing shingles and incorporating them into hot mix asphalt for use in applications such as asphalt pavement construction. Unlike previous methods, the asphalt from ground shingles is mixed with and becomes an integral component of the asphalt binder, instead of acting primarily as part of the aggregate. The asphalt content of the shingles mixes with heated asphalt binder to produce a single asphalt phase, and the asphalt from the shingles acts as asphalt in the final composite. | 10-09-2014 |
20140242194 | USE OF NITRITE SALTS IN TREATING TISSUE DAMAGE - Methods of treating a subject who has an tissue damage or who is at risk for tissue necrosis are disclosed. Also disclosed are methods of treating a subject who has an inflammatory disorder. The methods can include administering to the subject a pharmaceutical composition comprising inorganic nitrite or a pharmaceutically acceptable salt thereof, for a time and in an amount sufficient to reduce the tissue damage. The subject can be diagnosed as having a medical condition that results tissue damage, for example, diabetes, peripheral artery disease, cardiovascular disease, defective wound healing, arthritis, inflammatory bowel disease, ischemia, or a bacterial infection, e.g., Group A staphylococcal infection. The methods can include the step of monitoring the course of treatment. | 08-28-2014 |
20140236195 | Soft Tissue Fixation Device - A soft tissue fixation device for use in ACL or CrCL reconstruction has a base member provided with a passageway extending perpendicularly from its top surface through its bottom surface. The passageway is sized to allow soft tissue to be inserted through the passageway. The fixation device also includes an affixing member attachable to the base member. The base member has a notched section in the top surface extending from the passageway to a first perimeter section of the base member sized to accommodate at least a portion of the graft. Either surgical grade tissue glue or at least one perpendicularly extending spike is used to secure the base member to the bone. The base member is also provided with a sleeve whose interior wall surfaces form a part of the passageway and is sized to be inserted into the bone opening. The affixing member is provided with a series of teeth members extending downward from its lower surface. The teeth members are positioned so that when the affixing member is attached to the base member the teeth members will extend across and into the notched section of the top surface of the base member. The opposite ends of the affixing member is shaped to fit into aligned notches positioned along perimeter sections of the base member bottom surface for attaching the clip member to the base member. | 08-21-2014 |
20140127329 | USE OF NITRITES FOR THE TREATMENT OF CEREBRAL AMYLOID ANGIOPATHY, AGE ASSOCIATED DEMENTIA, AND COGNITIVE DECLINE - The present invention relates to the medical use of nitrites, such as inorganic nitrites, or any pharmaceutically acceptable salts, solvates, compositions, or prodrugs thereof, in the treatment of conditions that benefit from increased cerebral vascular flow. The pharmaceutical compositions used in these methods, which can be formulated for oral administration, can provide immediate release or extended release of the nitrite ion (NO | 05-08-2014 |
20140112902 | METHODS FOR TREATMENT OF INFLAMMATORY AND INFECTIOUS DISEASES - Methods and therapeutic treatments of diseases such as viral infections are provided including applying peg-Arginase I. Methods are provided that treat inflammation mediated diseases with peg-Arginase I. | 04-24-2014 |
20140105906 | Peptide for Protection of Allergic Respiratory Disorders - A peptide (Peptide-1) based on the C-terminal of Equine CC10 has been discovered that can be used as a vaccine to protect horses from respiratory airway obstruction (RAO). Antibodies to Peptide-1 may also be administered for short-term passive immunotherapy to RAO-affected horses, and can be used to measure the level of CC10 protein in serum to identify potential RAO horses (horses with reduced CC10). Due to similarities between equine RAO and human asthma, this peptide or its antibodies may also be useful in treatment or prevention of human asthma. | 04-17-2014 |
20140094381 | Predictive Biomarkers for Response to Exercise - A set of biomarkers have been identified that allows one to predict subjects who will respond to an exercise regime in term of cardiorespiratory fitness as assessed by maximal oxygen uptake. These predictions may be used, for example, to predict risk of cardiovascular disease, to design a more effective program for cardiac rehabilitation, to predict capacity for athletic performance or physically demanding occupation, and to predict ability to maintain functional capacity with aging using exercise. | 04-03-2014 |
20140088308 | Fluoride-Releasing Compositions - Chelating monomers and fluoride-releasing compositions are disclosed that may be incorporated into dental composite restorative materials, dental bonding agents or other dental materials, to produce materials with high fluoride release rates, and high fluoride recharge capability. Such dental restorative materials may help reduce the level of dental caries in patients, particularly the level of caries occurring on the margins of the restorative materials. | 03-27-2014 |
20140082803 | Smooth cordgrass name "LA11-101" - A new variety of smooth cordgrass identified as ‘LA11-101’ is disclosed as being genetically different from ‘Vermilion’, the only other smooth cordgrass variety for the northern Gulf of Mexico, and as having rapid establishment and growth in natural brackish and saline marsh environments, and excellent seed set and germination. | 03-20-2014 |
20140082802 | Smooth cordgrass named 'LA11-103' - A new variety of smooth cordgrass identified as ‘LA11-103’ is disclosed as being genetically different from ‘Vermilion’, ‘LA11-101’, and ‘LA11-102’, as having rapid establishment and growth in natural brackish and saline marsh environments, and excellent seed set and germination. | 03-20-2014 |
20140082801 | Smooth cordgrass named 'LA11-102' - A new variety of smooth cordgrass identified as ‘LA11-102’ is disclosed as being genetically different from ‘Vermilion’ and ‘LA11-101’ and as having rapid establishment and growth in natural brackish and saline marsh environments, and excellent seed set and germination. | 03-20-2014 |
20140073565 | CXCR4 AND ROBO1 EXPRESSION AS MARKERS FOR AUTOIMMUNE DIABETES - CXCR4 and ROBO-1 are biomarkers associated with type 1 diabetes. Expression of CXCR4 and ROBO-1 in peripheral CD3 T cells is substantially higher in patients with autoimmune diabetes (type 1 diabetes) than in non-diabetic patients. Therapies are disclosed for reducing the progression of type 1 diabetes, and to reduce the risk of developing type 1 diabetes in patients who are at risk of developing type 1 diabetes. | 03-13-2014 |
20140068802 | Rice Cultivar Designated 'CL131' - A novel rice cultivar, designated ‘CL131,’ is disclosed. The invention relates to the seeds of rice cultivar ‘CL131,’ to the plants of rice ‘CL131,’ and to methods for producing a rice plant produced by crossing the cultivar ‘CL131’ with itself or another rice variety, and to single gene conversions of such plants. The invention further relates to hybrid rice seeds and plants produced by crossing the cultivar ‘CL131’ with another rice cultivar. The invention further relates to other derivatives of the cultivar ‘CL131.’ | 03-06-2014 |
20140067285 | Fatigue Monitoring for Composite Materials - Fatigue failure in composite materials can be successfully modeled and predicted by monitoring irreversible gains in entropy. Permanent degradations in composites are marked by irreversible processes that are characterized by increases in entropy. By measuring changes in entropy, one can model and predict the deterioration and failure of composites. The technique may be used to predict the deterioration and failure of composites under essentially any type of loading—constant, variable, bending, torsion, tension, compression, or other. | 03-06-2014 |
20140026468 | Control of Subterranean Termites - A biological control is disclosed for termites, including subterranean termites such as | 01-30-2014 |
20140017783 | Non-Enzymatic Method for Isolating Human Adipose-Derived Stromal Stem Cells - A simple method was developed to extract adipose-derived stromal stem cells (ASCs) without using enzymatic digestion of the collagen in adipose tissue. The resulting ASCs isolated by the simple wash method have lower levels of CD34 expression, a hematopoietic stem cell marker, as compared to ASCs isolated using conventional enzymatic digestion using collagenase. This characteristic is consistent with non-enzymatically treated stem cells obtained from bone marrow aspirates, which are negative for CD34. Additionally, the washed ASCs have higher levels of CD44 expression, a hyaluronate receptor, and lower levels of contaminating hematopoietic cells, as evidenced by low CD45 expression, as compared to enzymatically digested cells. The cells produced by this simple method can be used therapeutically for allogenic or autologous tissue regeneration, and can be administered using any pharmaceutically acceptable carrier. In addition, the cells can be administered in a matrix, lattice, scaffold, or other biologically compatible materials. | 01-16-2014 |
20130344049 | METHODS FOR TREATMENT OF OCULAR DISEASES - Methods and therapeutic treatments of ocular diseases are provided including applying peg-Arginase I to affected eyes. Methods are provided that simultaneously treat inflammation and neovascularization of eyes while promoting healing. Methods are provided to treat lesions or infections of an eye. | 12-26-2013 |
20130315857 | Kexin-Derived Vaccines to Prevent or Treat Fungal Infections - A vaccine is disclosed that promotes CD4+ T cell-independent host defense mechanisms to defend against infection by fungi such as | 11-28-2013 |
20130295670 | Enrichment of Stem Cells from Adult Tissues - Subjecting a heterogeneous cell population (one with both stem cells and non-stem cells) to extreme stress selectively eliminated the non-stem cells and resulted in the enrichment of stem cells in the population. The stress can take many forms, including without limitation, cell toxins, high temperature, high salt, and low oxygen (hypoxic) conditions. The number of stem cells remaining after stress were increased, and showed increased expression of traditional stem cell markers. The stem cells were shown to be capable of proliferation and differentiation into multiple types of cells. This method allows purification of stem cells from adult heterogeneous cell populations on a large scale basis without requirement of expensive equipment, and without requiring the presence of cell surface markers. Stem cells produced by the above method can be used for clinical applications, including tissue engineering. | 11-07-2013 |
20130283670 | Floating Pitfall Trap - A floating aquatic pitfall trap system is disclosed for long-term monitoring of hydro- and hygrophilous insects, including for example biological control agents associated with aquatic vegetation. | 10-31-2013 |
20130231280 | Novel Peptide Involved in Energy Homeostasis - The expression of a mRNA encoding a putative 76 amino acid, secreted protein (“Enho1”) was found to negatively correlate with fasting triglyceride and cholesterol levels. A recombinant adenovirus was used to increase the expression of Enho1 mRNA in two mouse models of obesity, KK-A | 09-05-2013 |
20130187672 | Electrical Resonance Detection of Particles and Analytes in Microfluidic Channels - A conductivity counter and method of determining conductivity of a fluid sample are disclosed. The counter is suitable for high-speed, accurate counting of discrete events or items, such as cancer cells, passing through a fluid sample cell. A variable frequency current source is used to supply an excitation current to a sample cell connected in parallel with an inductance or the electrical equivalence of an inductance. This configuration can be accurately modeled as a parallel RLC circuit when the system is operated at a stable frequency. The current source frequency is tuned to the resonance frequency of the equivalent RLC circuit, which effectively eliminates the capacitive and inductive components of the impedance, leaving only purely resistive components. The output signal is due to perturbations in the fluid sample, such as passing cancer cells. | 07-25-2013 |
20130167154 | ENERGY EFFICIENT JOB SCHEDULING IN HETEROGENEOUS CHIP MULTIPROCESSORS BASED ON DYNAMIC PROGRAM BEHAVIOR - Methods for efficient job scheduling in a heterogeneous chip multiprocessor that include logic comparisons of performance metrics to determine if programs should be moved from an advanced core to a simple core or vice versa. | 06-27-2013 |
20130133119 | SWEETPOTATO PLANT NAMED '07-146' - A new variety of sweetpotato identified as ‘07-146’ is disclosed having disease resistance to | 05-23-2013 |
20130133118 | Sweetpotato plant named '05-111' - A new variety of sweetpotato identified as ‘05-111’ is disclosed having disease resistance to both | 05-23-2013 |
20130130934 | EFFICIENT HIGH-THROUGHPUT SCREEN FOR IDENTIFYING NOVEL CHEMICAL COMPOUNDS WHICH DISRUPT THE FUNGAL VACUOLE - A high-throughput screening method for identifying new anti-fungal compounds, including: growing an adenine-requiring mutant fungus under conditions to induce bioaccumulation of P-ribosylaminoimidazole; treating the mutant fungus with chemical compounds; and determining if the chemical compounds cause white discoloration of the mutant fungus. A method to determine the effective concentration of an anti-fungal. A method to detect chemical disruption of the fungal vacuole of a fungus. | 05-23-2013 |
20130116414 | METHODS OF EXTRACTING CHEMICAL COMPOUNDS FROM ORGANISMS WITH RESISTANT CELL WALLS - A method is provided for extraction of chemical compounds from an organism having a cell wall that includes adding nanomaterials, which may be metallic nanofibers such as silver nanofibers, to the organism. | 05-09-2013 |
20130109011 | METHODS OF AND DEVICES FOR CAPTURING CIRCULATING TUMOR CELLS | 05-02-2013 |
20130108595 | Use of Adipose Tissue-Derived Stromal Cells in Spinal Fusion | 05-02-2013 |
20120312243 | AUTOMATED CONTINUOUS ZOOPLANKTON CULTURE SYSTEM - A system and method are disclosed for determining the concentration of zooplankton in a continuous zooplankton culture system. The system may include a transmissiometer, a sample tube, a first sample containing water and microalgae, and a second sample containing water, microalgae, and zooplankton. The concentration of zooplankton in the system may be calculated by comparing the transmissiometer output from the first sample and the second sample, wherein each of said outputs are obtained by moving each sample into the sample tube such that the transmissionmeter is positioned to take a reading across the tube. | 12-13-2012 |
20120274029 | MECHANICAL SEAL WITH TEXTURED SIDEWALL - The present invention discloses a mating ring, a primary ring, and associated mechanical seal having superior heat transfer and wear characteristics. According to an exemplary embodiment of the present invention, one or more dimples are formed onto the cylindrical outer surface of a mating ring sidewall and/or a primary ring sidewall. A stationary mating ring for a mechanical seal assembly is disclosed. Such a mating ring comprises an annular body having a central axis and a sealing face, wherein a plurality of dimples are formed into the outer circumferential surface of the annular body such that the exposed circumferential surface area of the annular body is increased. The texture added to the sidewall of the mating ring yields superior heat transfer and wear characteristics. | 11-01-2012 |
20110152836 | Method and Apparatus for Arterial and Venous Cannulation - A method and apparatus for cannulating vessels and cavities are provided. Such an apparatus includes a y-adaptor having a front leg configured to hold a needle, a guide-wire leg configured to receive a guide-wire, and a syringe leg configured to hold a syringe for aspiration. Once the needle is inserted into the desired vessel or cavity, the syringe may be aspirated to determine if the insertion was successful. Then, a guide-wire may be pushed into the guide-wire leg and into the needle via the front leg of the apparatus. Once the guide-wire has reached the targeted vessel or cavity, a catheter or cannula may be positioned over the guide wire and advanced to the desired location. | 06-23-2011 |
20110086828 | TREATMENT OF ALCOHOL ABUSE AND ALCOHOLISM USING MODULATORS OF NEUROSTEROID BINDING SITES ON GABAA RECEPTORS - The present invention provides methods for reducing alcohol drinking behavior in humans and treating acute alcohol poisoning through the use of neutral or negative modulating agents of the neurosteroid sites on GABA | 04-14-2011 |
20110076330 | USE OF ADIPOSE TISSUE-DERIVED STROMAL CELLS IN SPINAL FUSION - The present invention encompasses methods and compositions for treating a bone condition. The isolated adipose tissue-derived stromal cell of the invention and products related thereto have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications such as in spinal fusion procedures. | 03-31-2011 |
20100267629 | Enterostatin as Therapeutic Agent for Hypoglycemia - It has been discovered that enterostatin injections into mice caused an increase in blood glucose levels within 15 minutes of injection, and the glucose levels remained high for up to an hour after injection. In addition, mice injected with enterostatin showed less of an initial decrease in blood glucose following an insulin injection. Enterostatin was also shown to decrease AMPK activity in both mice and human tissues, which is additional support that glucose production is increased after enterostatin injection. This ability to enhance glucose production indicates that enterostatin could be used to treat hypoglycemia. | 10-21-2010 |
20100240933 | Lutein Extraction from Ozone-Treated Plant Sources - The use of ozonation has been discovered to increase the lutein extraction from aflatoxin-free corn and for some batches of alfalfa. In addition, the ozonation will substantially decrease any aflatoxin in the plant source. The structure of lutein as indicated by HPLC elution profile and the function of lutein using an antimutagenic activity was shown not to be affected by the ozonation. | 09-23-2010 |
20100168831 | Implantable clip-on micro-cuff electrode for functional stimulation and bio-potential recording - A nerve cuff electrode with a clip-on design feature is provided for the stimulation of nerves and nerve fibers and the recording of bio-potentials from nerves and nerve fibers. The nerve cuff includes an aperture having a longitudinal slit, a pinch hinge having a first arm and a second arm spaced apart from each other and at least one electrode embedded in the inner circumference of the aperture. The longitudinal slit is configured to open when a compressive force is applied to the outer surfaces of the first arm and the second arm whereby the first and second arm are squeezed together. When the compressive force is removed, the spring tension of the cuff returns the longitudinal slit to its normally closed position. | 07-01-2010 |
20100006437 | DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING COUPLED LIGASE DETECTION AND POLYMERASE CHAIN REACTIONS - The present invention relates to a method for identifying a target nucleotide sequence. This method involves forming a ligation product on a target nucleotide sequence in a ligase detection reaction mixture, amplifying the ligation product to form an amplified ligation product in a polymerase chain reaction (PCR) mixture, detecting the amplified ligation product, and identifying the target nucleotide sequence. Such coupling of the ligase detection reaction and the polymerase chain reaction permits multiplex detection of nucleic acid sequence differences. | 01-14-2010 |
20090148546 | Methods and compounds fo rthe treatment of obesity and obesity-related disorders - In certain embodiments, the invention comprises the use of plant-derived substances to reduce body fat and/or to increase insulin sensitivity in mammals. In certain embodiments, the invention comprises a composition for reducing the amount of fat in the body of a mammal, the composition comprising at least one plant-derived substance which inhibits adipogenesis in the body of the mammal and at least one plant-derived substance which promotes lipolysis in the body of the mammal. In certain embodiments, the invention comprises a composition for reducing the amount of fat in the body of a mammal, the composition comprising at least one plant-derived substance which inhibits adipogenesis in the body of the mammal, at least one plant-derived substance which promotes lipolysis in the body of the mammal, and at least one plant-derived substance which inhibits lipogenesis in the body of the mammal. In certain embodiments, capsaicin may be used in combination with other plant-derived substances to reduce the body fat in a mammalian subject. In one embodiment, an effective amount of a composition comprising capsaicin in combination with grape seed extract and/or genistein and/or caffeine may be administered to a subject to reduce the body fat of the subject. In one embodiment, a composition comprising grape seed extract is administered to a mammalian subject to increase insulin sensitivity. | 06-11-2009 |